CodeACT
NameAcetate
SynonymsAcetate ion (1-)
Identifierethanoate
FormulaC2 H3 O2
Molecular Weight59.044
SMILESCC(=O)[O-]
PubChem175
Formal Charge-1
Total Atoms7
Total Chiral Atoms0
Total Bonds6
Total Aromatic Bonds0
Networks1
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This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8J24 A Lipid Free fatty acid FFA2 Homo Sapiens Acetic acid - Gi1/Beta1/Gamma2 2.6 2024-01-24 10.1038/s41422-023-00914-z

A 2D representation of the interactions of ACT in 8J24
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:G86 R:R:Y90 2.9 0 No Yes 5 5 2 1
R:R:F89 R:R:Y90 5.16 2 Yes Yes 6 5 2 1
R:R:Y165 R:R:Y90 7.94 2 Yes Yes 4 5 1 1
R:R:Y238 R:R:Y90 8.94 2 Yes Yes 7 5 1 1
R:R:R255 R:R:Y90 5.14 2 Yes Yes 4 5 1 1
L:L:?1 R:R:Y90 15.34 2 Yes Yes 0 5 0 1
R:R:L183 R:R:Y94 7.03 0 No Yes 5 7 1 2
R:R:Y238 R:R:Y94 8.94 2 Yes Yes 7 7 1 2
R:R:N239 R:R:Y94 5.81 2 Yes Yes 8 7 2 2
R:R:H242 R:R:Y94 4.36 2 Yes Yes 6 7 1 2
R:R:H140 R:R:L183 3.86 0 No No 5 5 2 1
R:R:V144 R:R:Y165 10.09 0 No Yes 4 4 2 1
R:R:Q148 R:R:Y165 3.38 0 No Yes 5 4 2 1
L:L:?1 R:R:Y165 13.81 2 Yes Yes 0 4 0 1
R:R:R180 R:R:V176 3.92 2 Yes Yes 4 4 1 2
R:R:H242 R:R:R180 12.41 2 Yes Yes 6 4 1 1
R:R:R180 R:R:R255 10.66 2 Yes Yes 4 4 1 1
L:L:?1 R:R:R180 7.95 2 Yes Yes 0 4 0 1
L:L:?1 R:R:L183 7.24 2 Yes No 0 5 0 1
R:R:C184 R:R:N239 4.72 0 Yes Yes 5 8 2 2
R:R:C184 R:R:H242 4.42 0 Yes Yes 5 6 2 1
R:R:N239 R:R:Y238 4.65 2 Yes Yes 8 7 2 1
R:R:H242 R:R:Y238 10.89 2 Yes Yes 6 7 1 1
R:R:R255 R:R:Y238 6.17 2 Yes Yes 4 7 1 1
R:R:S262 R:R:Y238 3.82 0 No Yes 7 7 2 1
L:L:?1 R:R:Y238 7.67 2 Yes Yes 0 7 0 1
R:R:H242 R:R:S241 4.18 2 Yes Yes 6 4 1 2
R:R:P252 R:R:S241 5.34 2 Yes Yes 3 4 2 2
R:R:R255 R:R:S241 3.95 2 Yes Yes 4 4 1 2
L:L:?1 R:R:H242 3.36 2 Yes Yes 0 6 0 1
R:R:P252 R:R:R255 7.21 2 Yes Yes 3 4 2 1
L:L:?1 R:R:R255 4.77 2 Yes Yes 0 4 0 1
StatisticsValue
Average Number Of Links7.00
Average Number Of Links With An Hub6.00
Average Interaction Strength8.59
Average Nodes In Shell20.00
Average Hubs In Shell14.00
Average Links In Shell32.00
Average Links Mediated by Hubs In Shell31.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links7.00
Average Number Of Links With An Hub6.00
Average Interaction Strength8.59
Average Nodes In Shell20.00
Average Hubs In Shell14.00
Average Links In Shell32.00
Average Links Mediated by Hubs In Shell31.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)