psnGPCR

Show

PDB

Class

SubFamily

Type

SubType

Species

Orthosteric Ligand

Other Ligand(s)

Protein Partners

Resolution

Date

DOI

8ZJE

Peptide

Kisspeptin

Kiss1

Homo Sapiens

TAK-448

chim(NtGi1-Gq)/Beta1/Gamma1

3.07

2024-07-03

To be published

A 2D representation of the interactions of ACY in 8ZJE
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:T5	R:R:L102	7.37	0	No	Yes	0	5	1	2
L:L:?3	R:R:Y190	24.58	1	Yes	No	0	4	1	2
R:R:Y299	R:R:Y302	7.94	0	No	No	4	5	2	2
L:L:?2	R:R:Y299	5.61	1	No	No	0	4	1	2
L:L:T5	R:R:Y302	7.49	0	No	No	0	5	1	2
L:L:?1	L:L:?2	24.1	1	No	No	0	0	0	1
L:L:?1	L:L:?3	3.24	1	No	Yes	0	0	0	1
L:L:?1	L:L:T5	5.67	1	No	No	0	0	0	1
L:L:?2	L:L:?3	24.17	1	No	Yes	0	0	1	1
L:L:?3	L:L:F6	3.33	1	Yes	Yes	0	0	1	2
L:L:?3	L:L:?7	3.25	1	Yes	No	0	0	1	2

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	11.00
Average Nodes In Shell	10.00
Average Hubs In Shell	3.00
Average Links In Shell	11.00
Average Links Mediated by Hubs In Shell	6.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	11.00
Average Nodes In Shell	10.00
Average Hubs In Shell	3.00
Average Links In Shell	11.00
Average Links Mediated by Hubs In Shell	6.00

Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

Location of the nodes interacting with this ligand

(Click to enlarge 🔍)