CodeADP
NameAdenosine disphosphate
Synonyms
  • ADP
  • Adenosine disphosphate
Identifier
FormulaC10 H15 N5 O10 P2
Molecular Weight427.201
SMILES
PubChem6022
Formal Charge0
Total Atoms42
Total Chiral Atoms5
Total Bonds44
Total Aromatic Bonds10
Networks2
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This ligand is also present in the following 2 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8WJX A Nucleotide P2Y P2Y1 Homo sapiens ADP - chim(Gs-CtGq)/Beta1/Gamma2 3.2 2024-10-02 To be published

A 2D representation of the interactions of ADP in 8WJX
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?1 R:R:L44 13.71 2 Yes No 0 2 0 1
L:L:?1 R:R:Q50 8.53 2 Yes Yes 0 4 0 1
L:L:?1 R:R:Y110 6.83 2 Yes Yes 0 5 0 1
L:L:?1 R:R:Y111 4.78 2 Yes Yes 0 5 0 1
L:L:?1 R:R:T115 4.29 2 Yes Yes 0 4 0 1
L:L:?1 R:R:R128 3.54 2 Yes Yes 0 5 0 1
L:L:?1 R:R:R195 4.25 2 Yes No 0 1 0 1
L:L:?1 R:R:T201 4.29 2 Yes No 0 3 0 1
L:L:?1 R:R:D204 3.95 2 Yes Yes 0 6 0 1
L:L:?1 R:R:T205 4.29 2 Yes Yes 0 5 0 1
L:L:?1 R:R:N283 8.8 2 Yes No 0 4 0 1
L:L:?1 R:R:R287 10.62 2 Yes Yes 0 5 0 1
L:L:?1 R:R:N299 4.8 2 Yes No 0 2 0 1
L:L:?1 R:R:Y303 12.29 2 Yes Yes 0 4 0 1
L:L:?1 R:R:R310 8.49 2 Yes Yes 0 5 0 1
R:R:C42 R:R:N299 7.87 2 No No 8 2 2 1
R:R:C42 R:R:D300 3.11 2 No No 8 2 2 2
R:R:L44 R:R:Y303 11.72 2 No Yes 2 4 1 1
R:R:Q50 R:R:Y111 5.64 2 Yes Yes 4 5 1 1
R:R:Q50 R:R:T115 5.67 2 Yes Yes 4 4 1 1
R:R:Q50 R:R:Y303 13.53 2 Yes Yes 4 4 1 1
R:R:Q307 R:R:Q50 14.08 2 Yes Yes 5 4 2 1
R:R:Q50 R:R:R310 4.67 2 Yes Yes 4 5 1 1
R:R:F51 R:R:T115 7.78 0 Yes Yes 3 4 2 1
R:R:L54 R:R:Y58 4.69 2 Yes Yes 6 7 2 2
R:R:L54 R:R:Y111 5.86 2 Yes Yes 6 5 2 1
R:R:L54 R:R:Q307 7.99 2 Yes Yes 6 5 2 2
R:R:L54 R:R:R310 4.86 2 Yes Yes 6 5 2 1
R:R:L107 R:R:Y58 3.52 2 Yes Yes 7 7 2 2
R:R:Y111 R:R:Y58 4.96 2 Yes Yes 5 7 1 2
R:R:L107 R:R:Y111 4.69 2 Yes Yes 7 5 2 1
R:R:L107 R:R:R128 10.93 2 Yes Yes 7 5 2 1
R:R:Y110 R:R:Y111 12.91 2 Yes Yes 5 5 1 1
R:R:T115 R:R:Y110 7.49 2 Yes Yes 4 5 1 1
R:R:W117 R:R:Y110 5.79 2 Yes Yes 8 5 2 1
R:R:R128 R:R:Y110 5.14 2 Yes Yes 5 5 1 1
R:R:R128 R:R:Y111 4.12 2 Yes Yes 5 5 1 1
R:R:R310 R:R:Y111 8.23 2 Yes Yes 5 5 1 1
R:R:C202 R:R:W117 7.84 2 No Yes 9 8 2 2
R:R:R128 R:R:S190 5.27 2 Yes No 5 5 1 2
R:R:C202 R:R:R128 8.36 2 No Yes 9 5 2 1
R:R:D204 R:R:R128 19.06 2 Yes Yes 6 5 1 1
R:R:D204 R:R:H132 8.82 2 Yes Yes 6 5 1 2
R:R:R195 R:R:T199 5.17 2 No No 1 4 1 2
R:R:R195 R:R:T201 6.47 2 No No 1 3 1 1
R:R:T201 R:R:Y203 9.99 2 No No 3 4 1 2
R:R:D204 R:R:R310 3.57 2 Yes Yes 6 5 1 1
R:R:T205 R:R:T206 3.14 2 Yes Yes 5 5 1 2
R:R:T205 R:R:Y214 11.24 2 Yes Yes 5 4 1 2
R:R:L284 R:R:T205 5.9 2 No Yes 4 5 2 1
R:R:R287 R:R:T205 3.88 2 Yes Yes 5 5 1 1
R:R:T206 R:R:Y214 8.74 2 Yes Yes 5 4 2 2
R:R:D208 R:R:R287 4.76 0 No Yes 3 5 2 1
R:R:L211 R:R:R287 7.29 0 No Yes 4 5 2 1
R:R:L284 R:R:Y214 4.69 2 No Yes 4 4 2 2
R:R:F276 R:R:Y306 4.13 2 Yes Yes 7 4 2 2
R:R:F276 R:R:R310 5.34 2 Yes Yes 7 5 2 1
R:R:N283 R:R:R287 4.82 2 No Yes 4 5 1 1
R:R:N283 R:R:Y306 10.47 2 No Yes 4 4 1 2
R:R:D300 R:R:N299 6.73 2 No No 2 2 2 1
R:R:Q307 R:R:Y303 13.53 2 Yes Yes 5 4 2 1
R:R:Q307 R:R:Y306 5.64 2 Yes Yes 5 4 2 2
R:R:R310 R:R:Y306 19.55 2 Yes Yes 5 4 1 2
R:R:Q307 R:R:R310 8.18 2 Yes Yes 5 5 2 1
R:R:P55 R:R:Y111 2.78 0 No Yes 6 5 2 1
StatisticsValue
Average Number Of Links15.00
Average Number Of Links With An Hub10.00
Average Interaction Strength6.90
Average Nodes In Shell37.00
Average Hubs In Shell22.00
Average Links In Shell65.00
Average Links Mediated by Hubs In Shell59.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links12.00
Average Number Of Links With An Hub8.00
Average Interaction Strength7.83
Average Nodes In Shell30.50
Average Hubs In Shell18.00
Average Links In Shell52.00
Average Links Mediated by Hubs In Shell48.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)