CodeD7W
NameFenobam
Synonyms
  • Fenobam anhydrous
  • Fenobam
  • Fenobam hydrochloride
  • Fenobamum
  • Fenobam monohydrate
Identifier1-(3-chlorophenyl)-3-(3-methyl-5-oxidanylidene-4~{H}-imidazol-2-yl)urea
FormulaC11 H11 Cl N4 O2
Molecular Weight266.684
SMILESCN1CC(=O)N=C1NC(=O)Nc2cccc(c2)Cl
PubChem135659063
Formal Charge0
Total Atoms29
Total Chiral Atoms0
Total Bonds30
Total Aromatic Bonds6
Networks1
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This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
6FFH C Aminoacid Metabotropic glutamate mGlu5 Homo sapiens - Fenobam - 2.65 2018-03-07 10.1021/acs.jmedchem.7b01722

A 2D representation of the interactions of D7W in 6FFH
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:I625 R:R:Y629 4.84 1 Yes Yes 8 8 1 2
R:R:A810 R:R:I625 3.25 1 No Yes 7 8 1 1
R:R:I625 R:R:L814 5.71 1 Yes Yes 8 8 1 2
R:R:I625 W:W:?3006 3.37 1 Yes Yes 8 0 1 0
R:R:G628 R:R:S654 3.71 0 No No 6 7 2 1
R:R:A810 R:R:Y629 5.34 1 No Yes 7 8 1 2
R:R:C631 R:R:V806 3.42 0 No No 7 8 2 1
R:R:G652 R:R:P655 4.06 0 No Yes 5 8 2 1
R:R:P655 R:R:S654 5.34 1 Yes No 8 7 1 1
R:R:S654 W:W:?3006 5.32 1 No Yes 7 0 1 0
R:R:N747 R:R:P655 9.77 1 No Yes 7 8 2 1
R:R:P655 R:R:W785 4.05 1 Yes Yes 8 8 1 1
R:R:P655 W:W:?3006 14.55 1 Yes Yes 8 0 1 0
R:R:S658 W:W:?3006 6.21 0 No Yes 6 0 1 0
R:R:I751 R:R:Y659 12.09 1 Yes Yes 8 7 2 1
R:R:T781 R:R:Y659 6.24 1 No Yes 9 7 2 1
R:R:W785 R:R:Y659 11.58 1 Yes Yes 8 7 1 1
R:R:S809 R:R:Y659 3.82 1 No Yes 9 7 1 1
R:R:Y659 W:W:?3006 4.85 1 Yes Yes 7 0 1 0
R:R:L744 R:R:W785 4.56 0 No Yes 8 8 2 1
R:R:F788 R:R:L744 4.87 1 Yes No 9 8 1 2
R:R:N747 R:R:W785 5.65 1 No Yes 7 8 2 1
R:R:I751 R:R:T781 4.56 1 Yes No 8 9 2 2
R:R:I751 R:R:W785 11.74 1 Yes Yes 8 8 2 1
R:R:T781 R:R:W785 3.64 1 No Yes 9 8 2 1
R:R:S809 R:R:W785 6.18 1 No Yes 9 8 1 1
R:R:W785 W:W:?3006 24.22 1 Yes Yes 8 0 1 0
R:R:F788 R:R:Y792 14.44 1 Yes Yes 9 8 1 2
R:R:F788 R:R:M802 4.98 1 Yes No 9 8 1 2
R:R:F788 R:R:S805 6.61 1 Yes No 9 8 1 1
R:R:F788 W:W:?3006 15.11 1 Yes Yes 9 0 1 0
R:R:M802 R:R:Y792 7.18 1 No Yes 8 8 2 2
R:R:S805 W:W:?3006 4.44 1 No Yes 8 0 1 0
R:R:V806 W:W:?3006 10.56 0 No Yes 8 0 1 0
R:R:S809 W:W:?3006 8.87 1 No Yes 9 0 1 0
R:R:A810 W:W:?3006 3.72 1 No Yes 7 0 1 0
StatisticsValue
Average Number Of Links11.00
Average Number Of Links With An Hub5.00
Average Interaction Strength9.20
Average Nodes In Shell23.00
Average Hubs In Shell10.00
Average Links In Shell36.00
Average Links Mediated by Hubs In Shell34.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links11.00
Average Number Of Links With An Hub5.00
Average Interaction Strength9.20
Average Nodes In Shell23.00
Average Hubs In Shell10.00
Average Links In Shell36.00
Average Links Mediated by Hubs In Shell34.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)