psnGPCR

Show

PDB

Class

SubFamily

Type

SubType

Species

Orthosteric Ligand

Other Ligand(s)

Protein Partners

Resolution

Date

DOI

7F9Z

Peptide

Ghrelin

Homo Sapiens

GHRP-6

chim(NtGi1-Gs-CtGq)/Beta1/Gamma2

3.2

2021-08-18

doi.org/10.1038/s41467-021-25364-2

A 2D representation of the interactions of DHI in 7F9Z
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	L:L:?2	16.07	0	No	Yes	0	0	0	1
L:L:?1	R:R:Y106	10.12	0	No	No	0	3	0	1
L:L:?1	R:R:R199	5.24	0	No	No	0	3	0	1
L:L:?2	L:L:?3	30.01	3	Yes	Yes	0	0	1	2
L:L:?2	L:L:?6	9.47	3	Yes	Yes	0	0	1	2
L:L:?2	R:R:D99	5.37	3	Yes	No	0	6	1	2
L:L:?2	R:R:L103	8.76	3	Yes	No	0	4	1	2
L:L:?2	R:R:Q302	11.59	3	Yes	No	0	3	1	2
L:L:?2	R:R:F309	9.64	3	Yes	Yes	0	5	1	2
L:L:?6	R:R:D99	4.69	3	Yes	No	0	6	2	2
R:R:D99	R:R:F309	9.55	3	No	Yes	6	5	2	2
R:R:E197	R:R:Y106	8.98	0	No	No	4	3	2	1
R:R:E185	R:R:R199	20.93	0	No	No	1	3	2	1
R:R:E197	R:R:R199	5.82	0	No	No	4	3	2	1

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	10.48
Average Nodes In Shell	12.00
Average Hubs In Shell	4.00
Average Links In Shell	14.00
Average Links Mediated by Hubs In Shell	9.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

Statistics	Value
Average Number Of Links	3.50
Average Number Of Links With An Hub	1.50
Average Interaction Strength	9.60
Average Nodes In Shell	13.50
Average Hubs In Shell	5.50
Average Links In Shell	16.50
Average Links Mediated by Hubs In Shell	12.50

Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

Location of the nodes interacting with this ligand

(Click to enlarge 🔍)