CodeDSN
NameD-Serine
SynonymsD-Serine
Identifier(2R)-2-amino-3-hydroxy-propanoic acid
FormulaC3 H7 N O3
Molecular Weight105.093
SMILESC([C@H](C(=O)O)N)O
PubChem71077
Formal Charge0
Total Atoms14
Total Chiral Atoms1
Total Bonds13
Total Aromatic Bonds0
Networks1
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This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8JIU B1 Peptide Glucagon Glucagon Homo Sapiens SAR425899 - Gs/Beta1/Gamma2 2.76  2023-09-13 10.1073/pnas.2303696120

A 2D representation of the interactions of DSN in 8JIU
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?2 L:L:H1 3.54 0 Yes Yes 0 0 0 1
L:L:H1 R:R:Q232 7.42 0 Yes Yes 0 7 1 2
L:L:H1 R:R:I235 14.58 0 Yes No 0 5 1 2
L:L:H1 R:R:W304 9.52 0 Yes Yes 0 6 1 2
L:L:?2 L:L:T5 14.9 0 Yes No 0 0 0 1
L:L:?2 R:R:K381 3.89 0 Yes No 0 7 0 1
L:L:?2 R:R:L382 5.09 0 Yes No 0 5 0 1
L:L:T5 R:R:W304 8.49 5 No Yes 0 6 1 2
L:L:T5 R:R:D370 7.23 5 No Yes 0 4 1 2
R:R:D370 R:R:W304 5.58 5 Yes Yes 4 6 2 2
R:R:K381 R:R:V364 4.55 0 No No 7 6 1 2
R:R:K381 R:R:V368 9.11 0 No No 7 5 1 2
L:L:G4 L:L:H1 3.18 0 No Yes 0 0 2 1
StatisticsValue
Average Number Of Links4.00
Average Number Of Links With An Hub1.00
Average Interaction Strength6.86
Average Nodes In Shell12.00
Average Hubs In Shell5.00
Average Links In Shell13.00
Average Links Mediated by Hubs In Shell11.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links4.00
Average Number Of Links With An Hub1.00
Average Interaction Strength6.86
Average Nodes In Shell12.00
Average Hubs In Shell5.00
Average Links In Shell13.00
Average Links Mediated by Hubs In Shell11.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)