CodeE7P
Name(2S)-2-amino-4-phosphonobutanoic acid
Synonyms
Identifier
FormulaC4 H10 N O5 P
Molecular Weight183.1
SMILES
PubChem57689795
Formal Charge0
Total Atoms21
Total Chiral Atoms1
Total Bonds20
Total Aromatic Bonds0
Networks1
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This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8WG9 C Aminoacid Metabotropic Glutamate mGlu4; mGlu2 Homo Sapiens (2S)-2-amino-4-phosphonobutanoic acid - - 4.46 2024-11-27 doi.org/10.1038/s41467-024-54744-7

A 2D representation of the interactions of E7P in 8WG9
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?1 R:R:K74 39.1 7 Yes Yes 0 5 0 1
L:L:?1 R:R:R78 33.68 7 Yes Yes 0 4 0 1
L:L:?1 R:R:E403 6.95 7 Yes Yes 0 5 0 1
L:L:?1 R:R:K405 8.45 7 Yes No 0 4 0 1
R:R:F55 R:R:R78 9.62 7 No Yes 9 4 2 1
R:R:F55 R:R:Y179 17.54 7 No Yes 9 8 2 2
R:R:K74 R:R:P56 5.02 7 Yes No 5 5 1 2
R:R:K74 R:R:R78 3.71 7 Yes Yes 5 4 1 1
R:R:E403 R:R:H77 16 0 Yes No 5 6 1 2
R:R:R78 R:R:Y179 21.61 7 Yes Yes 4 8 1 2
R:R:R78 R:R:V409 15.69 7 Yes No 4 7 1 2
R:R:V409 R:R:Y179 10.09 7 No Yes 7 8 2 2
R:R:D312 R:R:K405 4.15 0 No No 8 4 2 1
R:R:E403 R:R:K317 8.1 0 Yes No 5 6 1 2
R:R:E403 R:R:V406 4.28 0 Yes No 5 6 1 2
R:R:F408 R:R:K405 7.44 0 No No 7 4 2 1
R:R:E403 R:R:G404 3.27 0 Yes No 5 5 1 2
R:R:G75 R:R:K74 1.74 0 No Yes 5 5 2 1
StatisticsValue
Average Number Of Links4.00
Average Number Of Links With An Hub3.00
Average Interaction Strength22.05
Average Nodes In Shell16.00
Average Hubs In Shell5.00
Average Links In Shell18.00
Average Links Mediated by Hubs In Shell16.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links4.00
Average Number Of Links With An Hub3.00
Average Interaction Strength22.05
Average Nodes In Shell16.00
Average Hubs In Shell5.00
Average Links In Shell18.00
Average Links Mediated by Hubs In Shell16.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)