CodeETA
NameEthanolamine
Synonyms
  • Ethanolamine acetate
  • Ethanolamine hydrochloride
  • Ethanolamine
Identifier2-azanylethanol
FormulaC2 H7 N O
Molecular Weight61.083
SMILESC(CO)N
PubChem700
Formal Charge0
Total Atoms11
Total Chiral Atoms0
Total Bonds10
Total Aromatic Bonds0
Networks3
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This ligand is also present in the following 3 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
6DDE A Peptide Opioid MOP Mus musculus Damgo - Gi1/Beta1/Gamma2 3.5 2018-06-13 10.1038/s41586-018-0219-7

A 2D representation of the interactions of ETA in 6DDE
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?4 R:R:Q124 9.1 0 Yes No 0 6 1 2
L:L:?4 R:R:W133 3.89 0 Yes Yes 0 8 1 2
L:L:?4 R:R:I144 13.41 0 Yes Yes 0 5 1 2
R:R:W318 R:R:Y299 12.54 2 Yes No 5 4 1 2
R:R:K303 R:R:W318 3.48 2 No Yes 4 5 1 1
L:L:?5 R:R:K303 5.76 2 No No 0 4 0 1
L:L:?2 R:R:W318 9.27 2 Yes Yes 0 5 2 1
L:L:?5 R:R:W318 6.21 2 No Yes 0 5 0 1
L:L:?2 L:L:G3 6.96 2 Yes No 0 0 2 2
L:L:?4 L:L:G3 8.77 0 Yes No 0 0 1 2
L:L:?4 L:L:?5 20.94 0 Yes No 0 0 1 0
StatisticsValue
Average Number Of Links3.00
Average Number Of Links With An Hub2.00
Average Interaction Strength10.97
Average Nodes In Shell10.00
Average Hubs In Shell5.00
Average Links In Shell11.00
Average Links Mediated by Hubs In Shell10.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
6DDF A Peptide Opioid MOP Mus musculus Damgo - Gi1/Beta1/Gamma2 3.5 2018-06-13 10.1038/s41586-018-0219-7

A 2D representation of the interactions of ETA in 6DDF
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:D147 R:R:Q124 2.61 1 Yes Yes 6 6 2 2
L:L:?4 R:R:Q124 6.82 1 Yes Yes 0 6 1 2
R:R:V143 R:R:W133 7.36 1 No Yes 5 8 2 2
R:R:C217 R:R:W133 20.89 1 Yes Yes 9 8 2 2
L:L:?4 R:R:W133 4.86 1 Yes Yes 0 8 1 2
L:L:?4 R:R:V143 3.82 1 Yes No 0 5 1 2
R:R:C217 R:R:I144 3.27 1 Yes Yes 9 5 2 2
L:L:?4 R:R:I144 10.97 1 Yes Yes 0 5 1 2
L:L:?4 R:R:D147 3.48 1 Yes Yes 0 6 1 2
L:L:?4 R:R:C217 4.07 1 Yes Yes 0 9 1 2
R:R:C321 R:R:I296 4.91 0 No Yes 6 6 2 2
R:R:I296 R:R:I322 2.94 1 Yes Yes 6 5 2 2
L:L:Y1 R:R:I296 3.63 1 Yes Yes 0 6 2 2
L:L:?2 R:R:I296 2.9 1 Yes Yes 0 6 1 2
R:R:K303 R:R:Y299 11.94 1 No No 4 4 1 2
R:R:W318 R:R:Y299 13.5 1 Yes No 5 4 1 2
R:R:K303 R:R:W318 3.48 1 No Yes 4 5 1 1
L:L:?5 R:R:K303 5.76 1 Yes No 0 4 0 1
R:R:C321 R:R:W318 2.61 0 No Yes 6 5 2 1
L:L:?2 R:R:W318 10.43 1 Yes Yes 0 5 1 1
L:L:?5 R:R:W318 7.76 1 Yes Yes 0 5 0 1
L:L:?2 R:R:I322 5.81 1 Yes Yes 0 5 1 2
L:L:?2 L:L:Y1 11.93 1 Yes Yes 0 0 1 2
L:L:?2 L:L:G3 6.96 1 Yes No 0 0 1 2
L:L:?2 L:L:?4 4.81 1 Yes Yes 0 0 1 1
L:L:?2 L:L:?5 7.67 1 Yes Yes 0 0 1 0
L:L:?4 L:L:G3 5.84 1 Yes No 0 0 1 2
L:L:?4 L:L:?5 20.94 1 Yes Yes 0 0 1 0
StatisticsValue
Average Number Of Links4.00
Average Number Of Links With An Hub3.00
Average Interaction Strength10.53
Average Nodes In Shell17.00
Average Hubs In Shell12.00
Average Links In Shell28.00
Average Links Mediated by Hubs In Shell27.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8EFQ A Peptide Opioid MOP Homo sapiens Damgo - Gi1/Beta1/Gamma2 3.3  2022-11-09 10.1016/j.cell.2022.09.041

A 2D representation of the interactions of ETA in 8EFQ
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?2 L:L:G3 6.96 2 Yes No 0 0 2 2
L:L:?2 L:L:?4 2.41 2 Yes Yes 0 0 2 1
L:L:?4 L:L:G3 10.23 2 Yes No 0 0 1 2
L:L:G3 R:R:Q126 3.29 2 No Yes 0 6 2 2
L:L:?4 R:R:Q126 9.1 2 Yes Yes 0 6 1 2
L:L:?4 R:R:N129 3.52 2 Yes No 0 4 1 2
L:L:?4 R:R:V145 3.82 2 Yes Yes 0 5 1 2
L:L:?4 L:L:?5 27.39 2 Yes No 0 0 1 0
R:R:K211 R:R:T220 3 24 No No 1 4 2 1
L:L:?5 R:R:T220 2.01 0 No No 0 4 0 1
StatisticsValue
Average Number Of Links2.00
Average Number Of Links With An Hub1.00
Average Interaction Strength14.70
Average Nodes In Shell9.00
Average Hubs In Shell4.00
Average Links In Shell10.00
Average Links Mediated by Hubs In Shell8.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links3.00
Average Number Of Links With An Hub2.00
Average Interaction Strength12.07
Average Nodes In Shell12.00
Average Hubs In Shell7.00
Average Links In Shell16.33
Average Links Mediated by Hubs In Shell15.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

missing image


Location of the nodes interacting with this ligand

(Click to enlarge 🔍)