Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7EUO | A | Peptide | Formylpeptide | FPR1-ALX | Homo sapiens | fMLF | - | Gi1/Beta1/Gamma2 | 2.9 | 2022-05-25 | 10.1038/s41467-022-32822-y |
![](/psngpcr/ligands/FME/FME_7EUO_L_L_1.png)
A 2D representation of the interactions of FME in 7EUO colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:F74 | R:R:V105 | 7.87 | 3 | Yes | Yes | 7 | 6 | 2 | 2 | R:R:F74 | R:R:L109 | 12.18 | 3 | Yes | Yes | 7 | 8 | 2 | 1 | R:R:L109 | R:R:V105 | 2.98 | 3 | Yes | Yes | 8 | 6 | 1 | 2 | L:L:L2 | R:R:V105 | 2.98 | 0 | No | Yes | 0 | 6 | 1 | 2 | R:R:D106 | R:R:F110 | 7.17 | 3 | Yes | Yes | 5 | 7 | 1 | 1 | R:R:D106 | R:R:T157 | 8.67 | 3 | Yes | No | 5 | 7 | 1 | 2 | R:R:D106 | R:R:V160 | 5.84 | 3 | Yes | Yes | 5 | 4 | 1 | 2 | R:R:D106 | R:R:R201 | 3.57 | 3 | Yes | Yes | 5 | 5 | 1 | 1 | L:L:?1 | R:R:D106 | 13.68 | 3 | Yes | Yes | 0 | 5 | 0 | 1 | R:R:L109 | R:R:W254 | 3.42 | 3 | Yes | Yes | 8 | 9 | 1 | 1 | L:L:?1 | R:R:L109 | 5.07 | 3 | Yes | Yes | 0 | 8 | 0 | 1 | R:R:F110 | R:R:F114 | 6.43 | 3 | Yes | No | 7 | 6 | 1 | 2 | R:R:F110 | R:R:L156 | 6.09 | 3 | Yes | No | 7 | 5 | 1 | 2 | L:L:?1 | R:R:F110 | 18.98 | 3 | Yes | Yes | 0 | 7 | 0 | 1 | R:R:V113 | R:R:W254 | 3.68 | 0 | No | Yes | 8 | 9 | 2 | 1 | R:R:T157 | R:R:V160 | 3.17 | 3 | No | Yes | 7 | 4 | 2 | 2 | R:R:F178 | R:R:R201 | 10.69 | 0 | Yes | Yes | 4 | 5 | 2 | 1 | R:R:L198 | R:R:R201 | 3.64 | 0 | No | Yes | 4 | 5 | 2 | 1 | L:L:F3 | R:R:L198 | 4.87 | 0 | Yes | No | 0 | 4 | 2 | 2 | L:L:?1 | R:R:R201 | 12.25 | 3 | Yes | Yes | 0 | 5 | 0 | 1 | R:R:R205 | R:R:Y257 | 4.12 | 3 | Yes | Yes | 6 | 7 | 1 | 1 | R:R:Q258 | R:R:R205 | 7.01 | 3 | Yes | Yes | 8 | 6 | 2 | 1 | R:R:A261 | R:R:R205 | 4.15 | 0 | No | Yes | 6 | 6 | 2 | 1 | L:L:?1 | R:R:R205 | 11.13 | 3 | Yes | Yes | 0 | 6 | 0 | 1 | L:L:F3 | R:R:R205 | 6.41 | 0 | Yes | Yes | 0 | 6 | 2 | 1 | R:R:F250 | R:R:W254 | 3.01 | 0 | No | Yes | 9 | 9 | 2 | 1 | R:R:W254 | R:R:Y257 | 2.89 | 3 | Yes | Yes | 9 | 7 | 1 | 1 | R:R:Q258 | R:R:W254 | 3.29 | 3 | Yes | Yes | 8 | 9 | 2 | 1 | R:R:A290 | R:R:W254 | 5.19 | 3 | No | Yes | 8 | 9 | 2 | 1 | R:R:N293 | R:R:W254 | 9.04 | 0 | No | Yes | 9 | 9 | 2 | 1 | L:L:?1 | R:R:W254 | 3.13 | 3 | Yes | Yes | 0 | 9 | 0 | 1 | R:R:T286 | R:R:Y257 | 7.49 | 0 | No | Yes | 7 | 7 | 2 | 1 | R:R:A290 | R:R:Y257 | 2.67 | 3 | No | Yes | 8 | 7 | 2 | 1 | L:L:?1 | R:R:Y257 | 4.3 | 3 | Yes | Yes | 0 | 7 | 0 | 1 | L:L:?1 | L:L:L2 | 3.81 | 3 | Yes | No | 0 | 0 | 0 | 1 | L:L:?1 | R:R:G209 | 1.57 | 3 | Yes | No | 0 | 6 | 0 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 9.00 | Average Number Of Links With An Hub | 7.00 | Average Interaction Strength | 8.21 | Average Nodes In Shell | 26.00 | Average Hubs In Shell | 14.00 | Average Links In Shell | 36.00 | Average Links Mediated by Hubs In Shell | 36.00 |
| ![](/psngpcr/ligands/FME/FME_7EUO_L_L_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/FME/FME_7EUO_L_L_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7T6T | A | Peptide | Formylpeptide | FPR1-ALX | Homo sapiens | fMLFII | - | Gi1/Beta1/Gamma2 | 3.2 | 2022-03-30 | 10.1038/s41467-022-28586-0 |
![](/psngpcr/ligands/FME/FME_7T6T_L_L_1.png)
A 2D representation of the interactions of FME in 7T6T colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | L:L:?1 | R:R:D106 | 17.41 | 2 | Yes | Yes | 0 | 5 | 0 | 1 | L:L:?1 | R:R:L109 | 5.07 | 2 | Yes | Yes | 0 | 8 | 0 | 1 | L:L:?1 | R:R:F110 | 22.33 | 2 | Yes | Yes | 0 | 7 | 0 | 1 | L:L:?1 | R:R:V113 | 4.1 | 2 | Yes | Yes | 0 | 8 | 0 | 1 | L:L:?1 | R:R:R201 | 13.36 | 2 | Yes | Yes | 0 | 5 | 0 | 1 | L:L:?1 | R:R:R205 | 24.5 | 2 | Yes | Yes | 0 | 6 | 0 | 1 | L:L:?1 | R:R:W254 | 4.18 | 2 | Yes | Yes | 0 | 9 | 0 | 1 | L:L:?1 | R:R:Y257 | 6.45 | 2 | Yes | Yes | 0 | 7 | 0 | 1 | L:L:L2 | R:R:V105 | 4.47 | 2 | Yes | Yes | 0 | 6 | 2 | 2 | L:L:L2 | R:R:D106 | 4.07 | 2 | Yes | Yes | 0 | 5 | 2 | 1 | L:L:L2 | R:R:F291 | 3.65 | 2 | Yes | Yes | 0 | 7 | 2 | 2 | L:L:F3 | R:R:R205 | 8.55 | 2 | Yes | Yes | 0 | 6 | 2 | 1 | L:L:F3 | R:R:Y257 | 5.16 | 2 | Yes | Yes | 0 | 7 | 2 | 1 | L:L:F3 | R:R:A261 | 2.77 | 2 | Yes | No | 0 | 6 | 2 | 2 | R:R:F74 | R:R:V105 | 3.93 | 2 | Yes | Yes | 7 | 6 | 2 | 2 | R:R:F74 | R:R:L109 | 12.18 | 2 | Yes | Yes | 7 | 8 | 2 | 1 | R:R:F291 | R:R:F74 | 16.08 | 2 | Yes | Yes | 7 | 7 | 2 | 2 | R:R:L109 | R:R:V105 | 2.98 | 2 | Yes | Yes | 8 | 6 | 1 | 2 | R:R:D106 | R:R:T157 | 4.34 | 2 | Yes | Yes | 5 | 7 | 1 | 2 | R:R:D106 | R:R:V160 | 4.38 | 2 | Yes | Yes | 5 | 4 | 1 | 2 | R:R:D106 | R:R:R201 | 4.76 | 2 | Yes | Yes | 5 | 5 | 1 | 1 | R:R:L109 | R:R:W254 | 5.69 | 2 | Yes | Yes | 8 | 9 | 1 | 1 | R:R:F291 | R:R:L109 | 7.31 | 2 | Yes | Yes | 7 | 8 | 2 | 1 | R:R:F110 | R:R:F114 | 7.5 | 0 | Yes | Yes | 7 | 6 | 1 | 2 | R:R:F110 | R:R:L156 | 7.31 | 0 | Yes | No | 7 | 5 | 1 | 2 | R:R:F110 | R:R:G209 | 3.01 | 0 | Yes | No | 7 | 6 | 1 | 2 | R:R:P213 | R:R:V113 | 3.53 | 0 | Yes | Yes | 9 | 8 | 2 | 1 | R:R:F250 | R:R:V113 | 3.93 | 2 | Yes | Yes | 9 | 8 | 2 | 1 | R:R:V113 | R:R:W254 | 6.13 | 2 | Yes | Yes | 8 | 9 | 1 | 1 | R:R:F114 | R:R:P213 | 2.89 | 0 | Yes | Yes | 6 | 9 | 2 | 2 | R:R:T157 | R:R:V160 | 3.17 | 2 | Yes | Yes | 7 | 4 | 2 | 2 | R:R:F178 | R:R:P159 | 2.89 | 2 | Yes | No | 4 | 8 | 2 | 2 | R:R:P159 | R:R:R201 | 2.88 | 2 | No | Yes | 8 | 5 | 2 | 1 | R:R:R201 | R:R:V160 | 3.92 | 2 | Yes | Yes | 5 | 4 | 1 | 2 | R:R:F178 | R:R:R201 | 9.62 | 2 | Yes | Yes | 4 | 5 | 2 | 1 | R:R:R201 | R:R:R205 | 3.2 | 2 | Yes | Yes | 5 | 6 | 1 | 1 | R:R:G202 | R:R:R205 | 4.5 | 0 | No | Yes | 5 | 6 | 2 | 1 | R:R:R205 | R:R:Y257 | 8.23 | 2 | Yes | Yes | 6 | 7 | 1 | 1 | R:R:Q258 | R:R:R205 | 9.35 | 2 | Yes | Yes | 8 | 6 | 2 | 1 | R:R:A261 | R:R:R205 | 5.53 | 2 | No | Yes | 6 | 6 | 2 | 1 | R:R:G209 | R:R:P213 | 4.06 | 0 | No | Yes | 6 | 9 | 2 | 2 | R:R:F250 | R:R:W254 | 6.01 | 2 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:F250 | R:R:N293 | 4.83 | 2 | Yes | Yes | 9 | 9 | 2 | 2 | R:R:W254 | R:R:Y257 | 2.89 | 2 | Yes | Yes | 9 | 7 | 1 | 1 | R:R:Q258 | R:R:W254 | 3.29 | 2 | Yes | Yes | 8 | 9 | 2 | 1 | R:R:A290 | R:R:W254 | 7.78 | 2 | No | Yes | 8 | 9 | 2 | 1 | R:R:N293 | R:R:W254 | 9.04 | 2 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:Q258 | R:R:Y257 | 3.38 | 2 | Yes | Yes | 8 | 7 | 2 | 1 | R:R:A261 | R:R:Y257 | 2.67 | 2 | No | Yes | 6 | 7 | 2 | 1 | R:R:T286 | R:R:Y257 | 3.75 | 0 | No | Yes | 7 | 7 | 2 | 1 | R:R:S287 | R:R:Y257 | 3.82 | 0 | No | Yes | 6 | 7 | 2 | 1 | R:R:A290 | R:R:Y257 | 4 | 2 | No | Yes | 8 | 7 | 2 | 1 | R:R:F291 | R:R:S287 | 5.28 | 2 | Yes | No | 7 | 6 | 2 | 2 | |
Statistics | Value |
---|
Average Number Of Links | 8.00 | Average Number Of Links With An Hub | 8.00 | Average Interaction Strength | 12.18 | Average Nodes In Shell | 30.00 | Average Hubs In Shell | 22.00 | Average Links In Shell | 53.00 | Average Links Mediated by Hubs In Shell | 53.00 |
| ![](/psngpcr/ligands/FME/FME_7T6T_L_L_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/FME/FME_7T6T_L_L_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7T6V | A | Peptide | Formylpeptide | FPR2-ALX | Homo sapiens | fMLFII | - | Gi1/Beta1/Gamma2 | 3.1 | 2022-03-30 | 10.1038/s41467-022-28586-0 |
![](/psngpcr/ligands/FME/FME_7T6V_L_L_1.png)
A 2D representation of the interactions of FME in 7T6V colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:F74 | R:R:V105 | 7.87 | 0 | Yes | Yes | 7 | 6 | 2 | 2 | R:R:F74 | R:R:L109 | 10.96 | 0 | Yes | No | 7 | 8 | 2 | 1 | R:R:D106 | R:R:V105 | 4.38 | 6 | Yes | Yes | 5 | 6 | 1 | 2 | L:L:L2 | R:R:V105 | 4.47 | 6 | No | Yes | 0 | 6 | 2 | 2 | R:R:D106 | R:R:R201 | 4.76 | 6 | Yes | Yes | 5 | 5 | 1 | 1 | L:L:?1 | R:R:D106 | 18.66 | 6 | Yes | Yes | 0 | 5 | 0 | 1 | L:L:L2 | R:R:D106 | 5.43 | 6 | No | Yes | 0 | 5 | 2 | 1 | L:L:?1 | R:R:L109 | 6.34 | 6 | Yes | No | 0 | 8 | 0 | 1 | R:R:F110 | R:R:F114 | 6.43 | 0 | No | Yes | 7 | 6 | 1 | 2 | L:L:?1 | R:R:F110 | 23.44 | 6 | Yes | No | 0 | 7 | 0 | 1 | R:R:F178 | R:R:R201 | 9.62 | 6 | Yes | Yes | 4 | 5 | 2 | 1 | R:R:R201 | R:R:R205 | 8.53 | 6 | Yes | Yes | 5 | 5 | 1 | 1 | L:L:?1 | R:R:R201 | 12.25 | 6 | Yes | Yes | 0 | 5 | 0 | 1 | R:R:G202 | R:R:R205 | 6 | 0 | No | Yes | 4 | 5 | 2 | 1 | R:R:Q258 | R:R:R205 | 5.84 | 0 | No | Yes | 8 | 5 | 2 | 1 | L:L:?1 | R:R:R205 | 16.7 | 6 | Yes | Yes | 0 | 5 | 0 | 1 | L:L:F3 | R:R:R205 | 4.28 | 0 | No | Yes | 0 | 5 | 2 | 1 | R:R:F257 | R:R:T287 | 5.19 | 0 | No | No | 7 | 7 | 1 | 2 | L:L:?1 | R:R:F257 | 5.58 | 6 | Yes | No | 0 | 7 | 0 | 1 | R:R:A261 | R:R:R205 | 2.77 | 0 | No | Yes | 5 | 5 | 2 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 6.00 | Average Number Of Links With An Hub | 3.00 | Average Interaction Strength | 13.83 | Average Nodes In Shell | 17.00 | Average Hubs In Shell | 8.00 | Average Links In Shell | 20.00 | Average Links Mediated by Hubs In Shell | 19.00 |
| ![](/psngpcr/ligands/FME/FME_7T6V_L_L_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/FME/FME_7T6V_L_L_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7VFX | A | Peptide | Formylpeptide | FPR1-ALX | Homo sapiens | fMLF | - | Gi1/Beta1/Gamma2 | 2.8 | 2022-09-21 | 10.1038/s41467-022-32822-y |
![](/psngpcr/ligands/FME/FME_7VFX_L_L_1.png)
A 2D representation of the interactions of FME in 7VFX colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:F74 | R:R:L109 | 8.53 | 0 | Yes | No | 7 | 8 | 2 | 1 | R:R:D106 | R:R:F110 | 7.17 | 5 | No | Yes | 5 | 7 | 1 | 1 | R:R:D106 | R:R:T157 | 8.67 | 5 | No | Yes | 5 | 7 | 1 | 2 | L:L:?1 | R:R:D106 | 12.44 | 5 | Yes | No | 0 | 5 | 0 | 1 | L:L:?1 | R:R:L109 | 5.07 | 5 | Yes | No | 0 | 8 | 0 | 1 | R:R:F110 | R:R:F114 | 4.29 | 5 | Yes | Yes | 7 | 6 | 1 | 2 | R:R:F110 | R:R:L156 | 10.96 | 5 | Yes | No | 7 | 5 | 1 | 2 | L:L:?1 | R:R:F110 | 12.28 | 5 | Yes | Yes | 0 | 7 | 0 | 1 | R:R:F178 | R:R:R201 | 10.69 | 5 | Yes | Yes | 4 | 5 | 2 | 1 | R:R:R201 | R:R:R205 | 7.46 | 5 | Yes | Yes | 5 | 6 | 1 | 1 | L:L:?1 | R:R:R201 | 12.25 | 5 | Yes | Yes | 0 | 5 | 0 | 1 | R:R:G202 | R:R:R205 | 3 | 0 | No | Yes | 5 | 6 | 2 | 1 | L:L:?1 | R:R:R205 | 17.82 | 5 | Yes | Yes | 0 | 6 | 0 | 1 | L:L:F3 | R:R:R205 | 5.34 | 0 | No | Yes | 0 | 6 | 2 | 1 | R:R:T286 | R:R:Y257 | 7.49 | 0 | No | Yes | 7 | 7 | 2 | 1 | R:R:S287 | R:R:Y257 | 6.36 | 0 | No | Yes | 6 | 7 | 2 | 1 | R:R:A290 | R:R:Y257 | 4 | 0 | No | Yes | 8 | 7 | 2 | 1 | L:L:?1 | R:R:Y257 | 4.3 | 5 | Yes | Yes | 0 | 7 | 0 | 1 | L:L:?1 | L:L:I2 | 3.92 | 5 | Yes | No | 0 | 0 | 0 | 1 | R:R:P159 | R:R:R201 | 1.44 | 0 | No | Yes | 8 | 5 | 2 | 1 | R:R:A261 | R:R:R205 | 1.38 | 0 | No | Yes | 6 | 6 | 2 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 7.00 | Average Number Of Links With An Hub | 4.00 | Average Interaction Strength | 9.73 | Average Nodes In Shell | 20.00 | Average Hubs In Shell | 9.00 | Average Links In Shell | 21.00 | Average Links Mediated by Hubs In Shell | 21.00 |
| ![](/psngpcr/ligands/FME/FME_7VFX_L_L_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/FME/FME_7VFX_L_L_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7WVU | A | Peptide | Formylpeptide | FPR1-ALX | Homo sapiens | fMLF | - | Gi1/Beta1/Gamma2 | 3.3 | 2022-04-13 | 10.1038/s41467-022-29361-x |
![](/psngpcr/ligands/FME/FME_7WVU_L_L_1.png)
A 2D representation of the interactions of FME in 7WVU colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | L:L:L2 | R:R:F102 | 6.09 | 0 | No | Yes | 0 | 6 | 1 | 2 | R:R:L109 | R:R:V105 | 2.98 | 0 | No | Yes | 8 | 6 | 1 | 2 | R:R:D106 | R:R:F110 | 9.55 | 2 | No | Yes | 5 | 7 | 1 | 1 | R:R:D106 | R:R:T157 | 13.01 | 2 | No | Yes | 5 | 7 | 1 | 2 | L:L:?1 | R:R:D106 | 8.71 | 2 | Yes | No | 0 | 5 | 0 | 1 | R:R:F291 | R:R:L109 | 6.09 | 0 | Yes | No | 7 | 8 | 2 | 1 | L:L:?1 | R:R:L109 | 10.15 | 2 | Yes | No | 0 | 8 | 0 | 1 | R:R:A153 | R:R:F110 | 2.77 | 0 | No | Yes | 8 | 7 | 2 | 1 | R:R:F110 | R:R:L156 | 6.09 | 2 | Yes | No | 7 | 5 | 1 | 2 | L:L:?1 | R:R:F110 | 17.86 | 2 | Yes | Yes | 0 | 7 | 0 | 1 | R:R:V113 | R:R:W254 | 6.13 | 0 | No | Yes | 8 | 9 | 2 | 1 | R:R:T157 | R:R:V160 | 4.76 | 0 | Yes | Yes | 7 | 4 | 2 | 2 | R:R:F178 | R:R:V160 | 5.24 | 2 | Yes | Yes | 4 | 4 | 2 | 2 | R:R:R201 | R:R:V160 | 3.92 | 2 | Yes | Yes | 5 | 4 | 1 | 2 | R:R:F178 | R:R:R201 | 10.69 | 2 | Yes | Yes | 4 | 5 | 2 | 1 | R:R:R201 | R:R:R205 | 3.2 | 2 | Yes | Yes | 5 | 6 | 1 | 1 | L:L:?1 | R:R:R201 | 8.91 | 2 | Yes | Yes | 0 | 5 | 0 | 1 | R:R:G202 | R:R:R205 | 6 | 0 | No | Yes | 5 | 6 | 2 | 1 | R:R:A261 | R:R:R205 | 2.77 | 0 | No | Yes | 6 | 6 | 2 | 1 | L:L:?1 | R:R:R205 | 16.7 | 2 | Yes | Yes | 0 | 6 | 0 | 1 | L:L:F3 | R:R:R205 | 5.34 | 0 | No | Yes | 0 | 6 | 2 | 1 | R:R:F250 | R:R:W254 | 9.02 | 0 | No | Yes | 9 | 9 | 2 | 1 | R:R:W254 | R:R:Y257 | 2.89 | 2 | Yes | Yes | 9 | 7 | 1 | 1 | R:R:Q258 | R:R:W254 | 3.29 | 2 | Yes | Yes | 8 | 9 | 2 | 1 | R:R:A290 | R:R:W254 | 7.78 | 2 | No | Yes | 8 | 9 | 2 | 1 | R:R:N293 | R:R:W254 | 9.04 | 0 | Yes | Yes | 9 | 9 | 2 | 1 | L:L:?1 | R:R:W254 | 6.26 | 2 | Yes | Yes | 0 | 9 | 0 | 1 | R:R:Q258 | R:R:Y257 | 3.38 | 2 | Yes | Yes | 8 | 7 | 2 | 1 | R:R:T286 | R:R:Y257 | 7.49 | 0 | No | Yes | 7 | 7 | 2 | 1 | R:R:A290 | R:R:Y257 | 4 | 2 | No | Yes | 8 | 7 | 2 | 1 | L:L:?1 | R:R:Y257 | 9.67 | 2 | Yes | Yes | 0 | 7 | 0 | 1 | L:L:?1 | L:L:L2 | 6.34 | 2 | Yes | No | 0 | 0 | 0 | 1 | R:R:F110 | R:R:G111 | 1.51 | 2 | Yes | No | 7 | 7 | 1 | 2 | |
Statistics | Value |
---|
Average Number Of Links | 8.00 | Average Number Of Links With An Hub | 5.00 | Average Interaction Strength | 10.58 | Average Nodes In Shell | 27.00 | Average Hubs In Shell | 14.00 | Average Links In Shell | 33.00 | Average Links Mediated by Hubs In Shell | 33.00 |
| ![](/psngpcr/ligands/FME/FME_7WVU_L_L_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/FME/FME_7WVU_L_L_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7WVV | A | Peptide | Formylpeptide | FPR2-ALX | Homo sapiens | fMLFII | - | Gi2/Beta1/Gamma2 | 2.9 | 2022-04-13 | 10.1038/s41467-022-29361-x |
![](/psngpcr/ligands/FME/FME_7WVV_L_L_1.png)
A 2D representation of the interactions of FME in 7WVV colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | L:L:?1 | L:L:L2 | 3.81 | 4 | Yes | No | 0 | 0 | 0 | 1 | L:L:?1 | R:R:D106 | 14.93 | 4 | Yes | Yes | 0 | 5 | 0 | 1 | L:L:?1 | R:R:L109 | 8.88 | 4 | Yes | No | 0 | 8 | 0 | 1 | L:L:?1 | R:R:F110 | 16.75 | 4 | Yes | Yes | 0 | 7 | 0 | 1 | L:L:?1 | R:R:R201 | 11.13 | 4 | Yes | Yes | 0 | 5 | 0 | 1 | L:L:?1 | R:R:R205 | 22.27 | 4 | Yes | Yes | 0 | 5 | 0 | 1 | L:L:?1 | R:R:W254 | 6.26 | 4 | Yes | Yes | 0 | 9 | 0 | 1 | L:L:?1 | R:R:F257 | 6.7 | 4 | Yes | Yes | 0 | 7 | 0 | 1 | L:L:I4 | L:L:L2 | 4.28 | 0 | Yes | No | 0 | 0 | 2 | 1 | L:L:L2 | R:R:V105 | 5.96 | 0 | No | Yes | 0 | 6 | 1 | 2 | L:L:F3 | R:R:R205 | 3.21 | 4 | Yes | Yes | 0 | 5 | 2 | 1 | L:L:F3 | R:R:A261 | 2.77 | 4 | Yes | No | 0 | 5 | 2 | 2 | L:L:I4 | R:R:F178 | 5.02 | 0 | Yes | No | 0 | 4 | 2 | 2 | R:R:F74 | R:R:V105 | 5.24 | 4 | Yes | Yes | 7 | 6 | 2 | 2 | R:R:F74 | R:R:L109 | 8.53 | 4 | Yes | No | 7 | 8 | 2 | 1 | R:R:L109 | R:R:V105 | 2.98 | 4 | No | Yes | 8 | 6 | 1 | 2 | R:R:D106 | R:R:F110 | 8.36 | 4 | Yes | Yes | 5 | 7 | 1 | 1 | R:R:D106 | R:R:T157 | 10.12 | 4 | Yes | Yes | 5 | 7 | 1 | 2 | R:R:D106 | R:R:V160 | 5.84 | 4 | Yes | No | 5 | 4 | 1 | 2 | R:R:D106 | R:R:R201 | 3.57 | 4 | Yes | Yes | 5 | 5 | 1 | 1 | R:R:F110 | R:R:F114 | 3.22 | 4 | Yes | Yes | 7 | 6 | 1 | 2 | R:R:F110 | R:R:L156 | 10.96 | 4 | Yes | No | 7 | 5 | 1 | 2 | R:R:V113 | R:R:W254 | 4.9 | 0 | No | Yes | 7 | 9 | 2 | 1 | R:R:T157 | R:R:V160 | 3.17 | 4 | Yes | No | 7 | 4 | 2 | 2 | R:R:R201 | R:R:V160 | 3.92 | 4 | Yes | No | 5 | 4 | 1 | 2 | R:R:F178 | R:R:R201 | 8.55 | 0 | No | Yes | 4 | 5 | 2 | 1 | R:R:R201 | R:R:R205 | 4.26 | 4 | Yes | Yes | 5 | 5 | 1 | 1 | R:R:G202 | R:R:R205 | 4.5 | 0 | No | Yes | 4 | 5 | 2 | 1 | R:R:Q258 | R:R:R205 | 8.18 | 4 | Yes | Yes | 8 | 5 | 2 | 1 | R:R:A261 | R:R:R205 | 5.53 | 4 | No | Yes | 5 | 5 | 2 | 1 | R:R:F250 | R:R:W254 | 10.02 | 0 | No | Yes | 9 | 9 | 2 | 1 | R:R:F257 | R:R:W254 | 3.01 | 4 | Yes | Yes | 7 | 9 | 1 | 1 | R:R:Q258 | R:R:W254 | 3.29 | 4 | Yes | Yes | 8 | 9 | 2 | 1 | R:R:A291 | R:R:W254 | 7.78 | 4 | No | Yes | 8 | 9 | 2 | 1 | R:R:N294 | R:R:W254 | 6.78 | 0 | No | Yes | 9 | 9 | 2 | 1 | R:R:F257 | R:R:T287 | 9.08 | 4 | Yes | No | 7 | 7 | 1 | 2 | R:R:A291 | R:R:F257 | 5.55 | 4 | No | Yes | 8 | 7 | 2 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 8.00 | Average Number Of Links With An Hub | 6.00 | Average Interaction Strength | 11.34 | Average Nodes In Shell | 26.00 | Average Hubs In Shell | 14.00 | Average Links In Shell | 37.00 | Average Links Mediated by Hubs In Shell | 37.00 |
| ![](/psngpcr/ligands/FME/FME_7WVV_L_L_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/FME/FME_7WVV_L_L_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
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Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7WVW | A | Peptide | Formylpeptide | FPR2-ALX | Homo sapiens | fMYFINILTL | - | Gi2/Beta1/Gamma2 | 3.1 | 2022-04-13 | 10.1038/s41467-022-29361-x |
![](/psngpcr/ligands/FME/FME_7WVW_L_L_1.png)
A 2D representation of the interactions of FME in 7WVW colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | L:L:?1 | R:R:D106 | 7.46 | 3 | Yes | No | 0 | 5 | 0 | 1 | L:L:?1 | R:R:L109 | 6.34 | 3 | Yes | No | 0 | 8 | 0 | 1 | L:L:?1 | R:R:F110 | 16.75 | 3 | Yes | Yes | 0 | 7 | 0 | 1 | L:L:?1 | R:R:R201 | 13.36 | 3 | Yes | Yes | 0 | 5 | 0 | 1 | L:L:?1 | R:R:R205 | 24.5 | 3 | Yes | Yes | 0 | 5 | 0 | 1 | L:L:?1 | R:R:W254 | 5.22 | 3 | Yes | Yes | 0 | 9 | 0 | 1 | L:L:?1 | R:R:F257 | 6.7 | 3 | Yes | Yes | 0 | 7 | 0 | 1 | L:L:?1 | R:R:Q258 | 3.66 | 3 | Yes | Yes | 0 | 8 | 0 | 1 | R:R:F74 | R:R:L109 | 9.74 | 0 | Yes | No | 7 | 8 | 2 | 1 | R:R:D106 | R:R:F110 | 8.36 | 3 | No | Yes | 5 | 7 | 1 | 1 | R:R:D106 | R:R:T157 | 11.56 | 3 | No | Yes | 5 | 7 | 1 | 2 | R:R:F110 | R:R:F114 | 7.5 | 3 | Yes | Yes | 7 | 6 | 1 | 2 | R:R:F110 | R:R:L156 | 4.87 | 3 | Yes | No | 7 | 5 | 1 | 2 | R:R:V113 | R:R:W254 | 3.68 | 0 | No | Yes | 7 | 9 | 2 | 1 | R:R:T157 | R:R:V160 | 4.76 | 3 | Yes | No | 7 | 4 | 2 | 2 | R:R:R201 | R:R:V160 | 3.92 | 3 | Yes | No | 5 | 4 | 1 | 2 | R:R:F178 | R:R:R201 | 4.28 | 0 | Yes | Yes | 4 | 5 | 2 | 1 | R:R:R201 | R:R:R205 | 3.2 | 3 | Yes | Yes | 5 | 5 | 1 | 1 | R:R:Q258 | R:R:R205 | 7.01 | 3 | Yes | Yes | 8 | 5 | 1 | 1 | R:R:A261 | R:R:R205 | 5.53 | 0 | No | Yes | 5 | 5 | 2 | 1 | R:R:F210 | R:R:Q258 | 17.57 | 0 | Yes | Yes | 9 | 8 | 2 | 1 | R:R:F250 | R:R:W254 | 14.03 | 3 | No | Yes | 9 | 9 | 2 | 1 | R:R:F250 | R:R:N294 | 4.83 | 3 | No | Yes | 9 | 9 | 2 | 2 | R:R:C253 | R:R:W254 | 5.22 | 3 | No | Yes | 8 | 9 | 2 | 1 | R:R:C253 | R:R:N294 | 11.02 | 3 | No | Yes | 8 | 9 | 2 | 2 | R:R:Q258 | R:R:W254 | 5.48 | 3 | Yes | Yes | 8 | 9 | 1 | 1 | R:R:A291 | R:R:W254 | 5.19 | 0 | No | Yes | 8 | 9 | 2 | 1 | R:R:N294 | R:R:W254 | 7.91 | 3 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:F257 | R:R:T287 | 9.08 | 0 | Yes | No | 7 | 7 | 1 | 2 | R:R:F257 | R:R:S288 | 5.28 | 0 | Yes | No | 7 | 6 | 1 | 2 | L:L:F3 | R:R:F257 | 2.14 | 0 | No | Yes | 0 | 7 | 2 | 1 | R:R:F110 | R:R:G111 | 1.51 | 3 | Yes | No | 7 | 7 | 1 | 2 | R:R:F114 | R:R:G111 | 1.51 | 3 | Yes | No | 6 | 7 | 2 | 2 | R:R:A153 | R:R:F110 | 1.39 | 3 | No | Yes | 8 | 7 | 2 | 1 | R:R:A153 | R:R:F114 | 1.39 | 3 | No | Yes | 8 | 6 | 2 | 2 | |
Statistics | Value |
---|
Average Number Of Links | 8.00 | Average Number Of Links With An Hub | 6.00 | Average Interaction Strength | 10.50 | Average Nodes In Shell | 27.00 | Average Hubs In Shell | 13.00 | Average Links In Shell | 35.00 | Average Links Mediated by Hubs In Shell | 35.00 |
| ![](/psngpcr/ligands/FME/FME_7WVW_L_L_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/FME/FME_7WVW_L_L_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
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Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7WVX | A | Peptide | Formylpeptide | FPR2-ALX | Homo sapiens | Humanin | - | Gi2/Beta1/Gamma2 | 2.8 | 2022-04-13 | 10.1038/s41467-022-29361-x |
![](/psngpcr/ligands/FME/FME_7WVX_L_L_1.png)
A 2D representation of the interactions of FME in 7WVX colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | L:L:?1 | R:R:D106 | 9.95 | 4 | Yes | Yes | 0 | 5 | 0 | 1 | L:L:?1 | R:R:L109 | 6.34 | 4 | Yes | No | 0 | 8 | 0 | 1 | L:L:?1 | R:R:F110 | 20.09 | 4 | Yes | Yes | 0 | 7 | 0 | 1 | L:L:?1 | R:R:R201 | 14.48 | 4 | Yes | No | 0 | 5 | 0 | 1 | L:L:?1 | R:R:R205 | 25.61 | 4 | Yes | Yes | 0 | 5 | 0 | 1 | L:L:?1 | R:R:W254 | 6.26 | 4 | Yes | Yes | 0 | 9 | 0 | 1 | L:L:?1 | R:R:F257 | 4.47 | 4 | Yes | Yes | 0 | 7 | 0 | 1 | L:L:?1 | R:R:Q258 | 3.66 | 4 | Yes | Yes | 0 | 8 | 0 | 1 | L:L:P3 | R:R:F257 | 8.67 | 0 | No | Yes | 0 | 7 | 2 | 1 | R:R:D106 | R:R:F110 | 8.36 | 4 | Yes | Yes | 5 | 7 | 1 | 1 | R:R:D106 | R:R:T157 | 11.56 | 4 | Yes | Yes | 5 | 7 | 1 | 2 | R:R:D106 | R:R:V160 | 5.84 | 4 | Yes | No | 5 | 4 | 1 | 2 | R:R:F110 | R:R:F114 | 8.57 | 4 | Yes | Yes | 7 | 6 | 1 | 2 | R:R:F110 | R:R:L156 | 9.74 | 4 | Yes | No | 7 | 5 | 1 | 2 | R:R:T157 | R:R:V160 | 4.76 | 4 | Yes | No | 7 | 4 | 2 | 2 | R:R:F178 | R:R:R201 | 8.55 | 0 | No | No | 4 | 5 | 2 | 1 | R:R:R201 | R:R:R205 | 5.33 | 4 | No | Yes | 5 | 5 | 1 | 1 | R:R:Q258 | R:R:R205 | 8.18 | 4 | Yes | Yes | 8 | 5 | 1 | 1 | R:R:A261 | R:R:R205 | 5.53 | 0 | No | Yes | 5 | 5 | 2 | 1 | R:R:F210 | R:R:Q258 | 18.74 | 0 | Yes | Yes | 9 | 8 | 2 | 1 | R:R:F250 | R:R:W254 | 11.02 | 0 | No | Yes | 9 | 9 | 2 | 1 | R:R:Q258 | R:R:W254 | 5.48 | 4 | Yes | Yes | 8 | 9 | 1 | 1 | R:R:A291 | R:R:W254 | 7.78 | 0 | No | Yes | 8 | 9 | 2 | 1 | R:R:N294 | R:R:W254 | 7.91 | 0 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:F257 | R:R:T287 | 7.78 | 0 | Yes | No | 7 | 7 | 1 | 2 | R:R:A291 | R:R:F257 | 4.16 | 0 | No | Yes | 8 | 7 | 2 | 1 | L:L:?1 | L:L:A2 | 2.89 | 4 | Yes | No | 0 | 0 | 0 | 1 | R:R:F110 | R:R:G111 | 1.51 | 4 | Yes | No | 7 | 7 | 1 | 2 | R:R:F114 | R:R:G111 | 1.51 | 4 | Yes | No | 6 | 7 | 2 | 2 | |
Statistics | Value |
---|
Average Number Of Links | 9.00 | Average Number Of Links With An Hub | 6.00 | Average Interaction Strength | 10.42 | Average Nodes In Shell | 23.00 | Average Hubs In Shell | 11.00 | Average Links In Shell | 29.00 | Average Links Mediated by Hubs In Shell | 28.00 |
| ![](/psngpcr/ligands/FME/FME_7WVX_L_L_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/FME/FME_7WVX_L_L_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
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