CodeFO9
Namefamotidine
Synonyms
Identifier
FormulaC8 H17 N7 O2 S3
Molecular Weight339.461
SMILES
PubChem
Formal Charge0
Total Atoms37
Total Chiral Atoms0
Total Bonds37
Total Aromatic Bonds0
Networks1
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This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7UL3 A Amine Histamine H2 Homo sapiens Famotidine - - 3 2022-06-29 doi.org/10.1038/s41594-022-00859-8

A 2D representation of the interactions of FO9 in 7UL3
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?1 R:R:D98 12.07 2 Yes No 0 5 0 1
L:L:?1 R:R:V99 6.63 2 Yes No 0 4 0 1
L:L:?1 R:R:C102 4.71 2 Yes No 0 7 0 1
L:L:?1 R:R:T103 4.37 2 Yes No 0 6 0 1
L:L:?1 R:R:V176 8.83 2 Yes No 0 5 0 1
L:L:?1 R:R:D186 10.06 2 Yes No 0 4 0 1
L:L:?1 R:R:T190 8.74 2 Yes No 0 5 0 1
L:L:?1 R:R:Y250 15.64 2 Yes Yes 0 6 0 1
L:L:?1 R:R:L274 5.13 2 Yes No 0 5 0 1
R:R:D98 R:R:V71 7.3 0 No No 5 6 1 2
R:R:D98 R:R:Y278 6.9 0 No Yes 5 6 1 2
R:R:C102 R:R:I106 3.27 0 No No 7 7 1 2
R:R:S146 R:R:T103 6.4 0 No No 8 6 2 1
R:R:F254 R:R:V176 3.93 0 Yes No 4 5 2 1
R:R:D186 R:R:Y182 6.9 2 No Yes 4 5 1 2
R:R:D186 R:R:T190 4.34 2 No No 4 5 1 1
R:R:W247 R:R:Y250 6.75 2 Yes Yes 8 6 2 1
R:R:F251 R:R:W247 6.01 2 No Yes 7 8 2 2
R:R:F251 R:R:Y250 4.13 2 No Yes 7 6 2 1
R:R:F254 R:R:Y250 5.16 0 Yes Yes 4 6 2 1
R:R:R257 R:R:Y250 3.09 0 No Yes 4 6 2 1
R:R:V273 R:R:Y250 3.79 0 No Yes 5 6 2 1
R:R:L274 R:R:Y278 9.38 0 No Yes 5 6 1 2
L:L:?1 R:R:K175 1.05 2 Yes No 0 4 0 1
StatisticsValue
Average Number Of Links10.00
Average Number Of Links With An Hub1.00
Average Interaction Strength7.72
Average Nodes In Shell21.00
Average Hubs In Shell6.00
Average Links In Shell24.00
Average Links Mediated by Hubs In Shell20.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links10.00
Average Number Of Links With An Hub1.00
Average Interaction Strength7.72
Average Nodes In Shell21.00
Average Hubs In Shell6.00
Average Links In Shell24.00
Average Links Mediated by Hubs In Shell20.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)