CodeHF2
Name(2R)-2-hydroxy-3-phenylpropanoic acid
Synonyms
Identifier
FormulaC9 H10 O3
Molecular Weight166.174
SMILES
PubChem643327
Formal Charge0
Total Atoms22
Total Chiral Atoms1
Total Bonds22
Total Aromatic Bonds6
Networks2
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This ligand is also present in the following 2 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
9JKT A Alicarboxylic acid Hydroxycarboxylic Acid HCA3 Homo Sapiens (2R)-2-hydroxy-3-phenylpropanoic acid - Gi1/Beta1/Gamma2 3.05 2025-10-29 To be published

A 2D representation of the interactions of HF2 in 9JKT
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?1 R:R:V83 12.95 1 Yes No 0 6 0 1
L:L:?1 R:R:Y86 3.06 1 Yes No 0 5 0 1
L:L:?1 R:R:Y87 9.17 1 Yes No 0 5 0 1
L:L:?1 R:R:L104 6.02 1 Yes Yes 0 5 0 1
L:L:?1 R:R:F107 28.59 1 Yes No 0 6 0 1
L:L:?1 R:R:R111 9.5 1 Yes No 0 7 0 1
L:L:?1 R:R:Y284 18.34 1 Yes No 0 7 0 1
R:R:I26 R:R:Y87 3.63 0 No No 4 5 2 1
R:R:V83 R:R:Y87 5.05 1 No No 6 5 1 1
R:R:F107 R:R:V83 5.24 1 No No 6 6 1 1
R:R:W93 R:R:Y86 2.89 1 Yes No 9 5 2 1
R:R:C100 R:R:W93 5.22 1 No Yes 9 9 2 2
R:R:V103 R:R:W93 3.68 0 No Yes 5 9 2 2
R:R:C177 R:R:W93 13.06 1 No Yes 9 9 2 2
R:R:C100 R:R:L104 3.17 1 No Yes 9 5 2 1
R:R:C100 R:R:C177 7.28 1 No No 9 9 2 2
R:R:L104 R:R:V103 2.98 1 Yes No 5 5 1 2
R:R:C177 R:R:L104 4.76 1 No Yes 9 5 2 1
R:R:L104 R:R:S179 3 1 Yes No 5 5 1 2
R:R:F107 R:R:Y284 7.22 1 No No 6 7 1 1
R:R:E196 R:R:R111 11.63 0 Yes No 6 7 2 1
R:R:F244 R:R:R111 3.21 18 Yes No 9 7 2 1
R:R:S91 R:R:Y86 2.54 0 No No 4 5 2 1
R:R:E37 R:R:Y284 2.24 0 No No 7 7 2 1
StatisticsValue
Average Number Of Links7.00
Average Number Of Links With An Hub1.00
Average Interaction Strength12.52
Average Nodes In Shell18.00
Average Hubs In Shell5.00
Average Links In Shell24.00
Average Links Mediated by Hubs In Shell17.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links7.00
Average Number Of Links With An Hub1.00
Average Interaction Strength12.52
Average Nodes In Shell18.00
Average Hubs In Shell5.00
Average Links In Shell24.00
Average Links Mediated by Hubs In Shell17.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)