CodeHXD
Name(3R)-3-HYDROXYDODECANOIC ACID
Synonyms3-OH-DODECANOATE
Identifier(3R)-3-hydroxydodecanoic acid
FormulaC12 H24 O3
Molecular Weight216.317
SMILESCCCCCCCCC[C@H](CC(=O)O)O
PubChem5312804
Formal Charge0
Total Atoms39
Total Chiral Atoms1
Total Bonds38
Total Aromatic Bonds0
Networks1
 missing image

This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8J18 A Orphan A orphans GPR84 Homo sapiens (3R)-3-hydroxydodecanoic acid - Gi1/Beta1/Gamma2 2.89 2023-06-21 10.1038/s41467-023-38985-6

A 2D representation of the interactions of HXD in 8J18
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:L100 R:R:Y69 3.52 1 No Yes 8 8 1 2
R:R:S103 R:R:Y69 5.09 0 No Yes 6 8 2 2
R:R:F101 R:R:L100 6.09 1 Yes No 7 8 1 1
L:L:?1 R:R:L100 8.61 1 Yes No 0 8 0 1
R:R:F101 R:R:F152 13.93 1 Yes Yes 7 8 1 1
R:R:F101 R:R:F170 7.5 1 Yes No 7 6 1 2
L:L:?1 R:R:F101 9.47 1 Yes Yes 0 7 0 1
R:R:N104 R:R:S103 4.47 1 No No 7 6 1 2
R:R:N104 R:R:Y332 8.14 1 No Yes 7 8 1 1
L:L:?1 R:R:N104 14.95 1 Yes No 0 7 0 1
R:R:F152 R:R:S105 5.28 1 Yes Yes 8 7 1 2
R:R:S105 R:R:Y186 6.36 0 Yes Yes 7 8 2 1
R:R:I108 R:R:Y186 6.04 1 No Yes 8 8 1 1
R:R:I108 R:R:Y332 15.71 1 No Yes 8 8 1 1
L:L:?1 R:R:I108 4.44 1 Yes No 0 8 0 1
R:R:L109 R:R:Y186 10.55 0 No Yes 6 8 2 1
R:R:F152 R:R:S151 3.96 1 Yes No 8 7 1 2
R:R:L182 R:R:S151 9.01 1 No No 8 7 2 2
R:R:F152 R:R:L155 3.65 1 Yes Yes 8 8 1 2
R:R:F152 R:R:Y159 3.09 1 Yes Yes 8 5 1 2
R:R:F152 R:R:L182 4.87 1 Yes No 8 8 1 2
L:L:?1 R:R:F152 6.63 1 Yes Yes 0 8 0 1
R:R:L155 R:R:Y159 8.21 1 Yes Yes 8 5 2 2
R:R:V162 R:R:V165 3.21 0 No Yes 3 4 2 1
R:R:T167 R:R:V165 3.17 13 No Yes 4 4 2 1
R:R:R172 R:R:V165 3.92 1 Yes Yes 5 4 2 1
L:L:?1 R:R:V165 3.48 1 Yes Yes 0 4 0 1
R:R:F170 R:R:R172 16.03 0 No Yes 6 5 2 2
R:R:F335 R:R:R172 3.21 1 Yes Yes 8 5 1 2
R:R:N339 R:R:R172 4.82 1 No Yes 7 5 2 2
L:L:?1 R:R:Y186 10.03 1 Yes Yes 0 8 0 1
R:R:T359 R:R:Y332 4.99 1 No Yes 8 8 1 1
R:R:N362 R:R:Y332 9.3 1 Yes Yes 9 8 2 1
L:L:?1 R:R:Y332 3.65 1 Yes Yes 0 8 0 1
R:R:F335 R:R:N339 16.92 1 Yes No 8 7 1 2
R:R:F335 R:R:T359 5.19 1 Yes No 8 8 1 1
L:L:?1 R:R:F335 19.89 1 Yes Yes 0 8 0 1
L:L:?1 R:R:L336 5.38 1 Yes No 0 7 0 1
L:L:?1 R:R:A356 3.68 1 Yes No 0 6 0 1
L:L:?1 R:R:T359 11.46 1 Yes No 0 8 0 1
R:R:A355 R:R:F335 2.77 0 No Yes 6 8 2 1
StatisticsValue
Average Number Of Links12.00
Average Number Of Links With An Hub6.00
Average Interaction Strength8.47
Average Nodes In Shell28.00
Average Hubs In Shell13.00
Average Links In Shell41.00
Average Links Mediated by Hubs In Shell39.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links12.00
Average Number Of Links With An Hub6.00
Average Interaction Strength8.47
Average Nodes In Shell28.00
Average Hubs In Shell13.00
Average Links In Shell41.00
Average Links Mediated by Hubs In Shell39.00

missing image


Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

missing image


Location of the nodes interacting with this ligand

(Click to enlarge 🔍)