Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7EO4 | A | Lipid | Lysophospholipid (S1P) | S1P1 | Homo sapiens | BAF312 | - | Gi1/Beta1/Gamma2 | 2.86 | 2022-01-05 | 10.1038/s41589-021-00930-3 |
![](/psngpcr/ligands/J8C/J8C_7EO4_L_L_1.png)
A 2D representation of the interactions of J8C in 7EO4 colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:M124 | R:R:Y98 | 4.79 | 3 | No | Yes | 6 | 6 | 1 | 2 | R:R:L297 | R:R:Y98 | 5.86 | 0 | No | Yes | 5 | 6 | 1 | 2 | R:R:N101 | R:R:S105 | 2.98 | 3 | Yes | Yes | 5 | 4 | 1 | 1 | R:R:N101 | R:R:R120 | 7.23 | 3 | Yes | Yes | 5 | 6 | 1 | 2 | R:R:M124 | R:R:N101 | 5.61 | 3 | No | Yes | 6 | 5 | 1 | 1 | L:L:?1 | R:R:N101 | 9.09 | 3 | Yes | Yes | 0 | 5 | 0 | 1 | R:R:G106 | R:R:S105 | 3.71 | 0 | No | Yes | 4 | 4 | 2 | 1 | R:R:R120 | R:R:S105 | 6.59 | 3 | Yes | Yes | 6 | 4 | 2 | 1 | L:L:?1 | R:R:S105 | 9.94 | 3 | Yes | Yes | 0 | 4 | 0 | 1 | R:R:R120 | R:R:W117 | 3 | 3 | Yes | Yes | 6 | 9 | 2 | 2 | R:R:E121 | R:R:W117 | 8.72 | 3 | Yes | Yes | 5 | 9 | 1 | 2 | R:R:E121 | R:R:L195 | 9.28 | 3 | Yes | Yes | 5 | 3 | 1 | 1 | R:R:E121 | R:R:Y198 | 8.98 | 3 | Yes | Yes | 5 | 4 | 1 | 2 | L:L:?1 | R:R:E121 | 4.39 | 3 | Yes | Yes | 0 | 5 | 0 | 1 | L:L:?1 | R:R:M124 | 6.55 | 3 | Yes | No | 0 | 6 | 0 | 1 | R:R:F125 | R:R:Y202 | 6.19 | 3 | No | Yes | 5 | 7 | 1 | 2 | R:R:C206 | R:R:F125 | 2.79 | 3 | No | No | 6 | 5 | 1 | 1 | L:L:?1 | R:R:F125 | 17.74 | 3 | Yes | No | 0 | 5 | 0 | 1 | R:R:L128 | R:R:W269 | 5.69 | 0 | No | Yes | 6 | 8 | 1 | 2 | L:L:?1 | R:R:L128 | 6.42 | 3 | Yes | No | 0 | 6 | 0 | 1 | R:R:S129 | R:R:S171 | 4.89 | 0 | No | No | 6 | 8 | 1 | 2 | L:L:?1 | R:R:S129 | 7.95 | 3 | Yes | No | 0 | 6 | 0 | 1 | R:R:L213 | R:R:V132 | 4.47 | 0 | No | No | 8 | 7 | 2 | 1 | R:R:V132 | R:R:W269 | 3.68 | 0 | No | Yes | 7 | 8 | 1 | 2 | L:L:?1 | R:R:V132 | 3.95 | 3 | Yes | No | 0 | 7 | 0 | 1 | R:R:L195 | R:R:V194 | 4.47 | 3 | Yes | No | 3 | 4 | 1 | 2 | R:R:L195 | R:R:Y198 | 5.86 | 3 | Yes | Yes | 3 | 4 | 1 | 2 | L:L:?1 | R:R:L195 | 3.67 | 3 | Yes | Yes | 0 | 3 | 0 | 1 | R:R:Y198 | R:R:Y202 | 12.91 | 3 | Yes | Yes | 4 | 7 | 2 | 2 | R:R:C206 | R:R:Y202 | 2.69 | 3 | No | Yes | 6 | 7 | 1 | 2 | L:L:?1 | R:R:C206 | 7.36 | 3 | Yes | No | 0 | 6 | 0 | 1 | L:L:?1 | R:R:V209 | 2.96 | 3 | Yes | No | 0 | 5 | 0 | 1 | R:R:F210 | R:R:L214 | 2.44 | 0 | Yes | No | 7 | 5 | 1 | 2 | R:R:F210 | R:R:W269 | 12.03 | 0 | Yes | Yes | 7 | 8 | 1 | 2 | R:R:F210 | R:R:F273 | 10.72 | 0 | Yes | No | 7 | 6 | 1 | 2 | L:L:?1 | R:R:F210 | 5.65 | 3 | Yes | Yes | 0 | 7 | 0 | 1 | R:R:L272 | R:R:L276 | 2.77 | 0 | No | No | 6 | 6 | 2 | 1 | L:L:?1 | R:R:L276 | 4.58 | 3 | Yes | No | 0 | 6 | 0 | 1 | L:L:?1 | R:R:L297 | 4.58 | 3 | Yes | No | 0 | 5 | 0 | 1 | R:R:E121 | R:R:G122 | 1.64 | 3 | Yes | No | 5 | 6 | 1 | 2 | R:R:T208 | R:R:V209 | 1.59 | 0 | No | No | 4 | 5 | 2 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 14.00 | Average Number Of Links With An Hub | 5.00 | Average Interaction Strength | 6.77 | Average Nodes In Shell | 30.00 | Average Hubs In Shell | 12.00 | Average Links In Shell | 41.00 | Average Links Mediated by Hubs In Shell | 36.00 |
| ![](/psngpcr/ligands/J8C/J8C_7EO4_L_L_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/J8C/J8C_7EO4_L_L_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7EVY | A | Lipid | Lysophospholipid (S1P) | S1P1 | Homo sapiens | Siponimod | - | Gi1/Beta1/Gamma2 | 2.98 | 2021-09-29 | 10.1038/s41422-021-00566-x |
![](/psngpcr/ligands/J8C/J8C_7EVY_L_L_1.png)
A 2D representation of the interactions of J8C in 7EVY colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:K34 | R:R:Y29 | 4.78 | 1 | No | Yes | 6 | 7 | 1 | 1 | R:R:T109 | R:R:Y29 | 3.75 | 1 | No | Yes | 5 | 7 | 2 | 1 | R:R:W117 | R:R:Y29 | 2.89 | 1 | Yes | Yes | 9 | 7 | 2 | 1 | R:R:P196 | R:R:Y29 | 5.56 | 0 | No | Yes | 3 | 7 | 2 | 1 | L:L:?1 | R:R:Y29 | 6.21 | 1 | Yes | Yes | 0 | 7 | 0 | 1 | L:L:?1 | R:R:K34 | 8.4 | 1 | Yes | No | 0 | 6 | 0 | 1 | R:R:M124 | R:R:Y98 | 3.59 | 1 | Yes | Yes | 6 | 6 | 1 | 2 | R:R:L297 | R:R:Y98 | 3.52 | 1 | No | Yes | 5 | 6 | 1 | 2 | R:R:M124 | R:R:N101 | 7.01 | 1 | Yes | No | 6 | 5 | 1 | 2 | R:R:T109 | R:R:W117 | 2.43 | 1 | No | Yes | 5 | 9 | 2 | 2 | R:R:E121 | R:R:W117 | 16.36 | 1 | Yes | Yes | 5 | 9 | 1 | 2 | R:R:L195 | R:R:W117 | 4.56 | 1 | Yes | Yes | 3 | 9 | 1 | 2 | R:R:W117 | R:R:Y198 | 3.86 | 1 | Yes | Yes | 9 | 4 | 2 | 2 | R:R:E121 | R:R:L195 | 2.65 | 1 | Yes | Yes | 5 | 3 | 1 | 1 | R:R:E121 | R:R:Y198 | 5.61 | 1 | Yes | Yes | 5 | 4 | 1 | 2 | L:L:?1 | R:R:E121 | 8.77 | 1 | Yes | Yes | 0 | 5 | 0 | 1 | R:R:L297 | R:R:M124 | 2.83 | 1 | No | Yes | 5 | 6 | 1 | 1 | L:L:?1 | R:R:M124 | 3.74 | 1 | Yes | Yes | 0 | 6 | 0 | 1 | R:R:F125 | R:R:Y202 | 5.16 | 0 | No | Yes | 5 | 7 | 1 | 2 | L:L:?1 | R:R:F125 | 16.94 | 1 | Yes | No | 0 | 5 | 0 | 1 | R:R:L128 | R:R:W269 | 4.56 | 1 | No | Yes | 6 | 8 | 1 | 1 | L:L:?1 | R:R:L128 | 5.5 | 1 | Yes | No | 0 | 6 | 0 | 1 | L:L:?1 | R:R:S129 | 7.95 | 1 | Yes | No | 0 | 6 | 0 | 1 | R:R:L213 | R:R:V132 | 2.98 | 0 | No | No | 8 | 7 | 2 | 1 | R:R:V132 | R:R:W269 | 2.45 | 1 | No | Yes | 7 | 8 | 1 | 1 | L:L:?1 | R:R:V132 | 3.95 | 1 | Yes | No | 0 | 7 | 0 | 1 | R:R:L195 | R:R:V194 | 4.47 | 1 | Yes | Yes | 3 | 4 | 1 | 2 | R:R:D279 | R:R:V194 | 4.38 | 1 | Yes | Yes | 4 | 4 | 2 | 2 | R:R:L195 | R:R:Y198 | 5.86 | 1 | Yes | Yes | 3 | 4 | 1 | 2 | L:L:?1 | R:R:L195 | 8.25 | 1 | Yes | Yes | 0 | 3 | 0 | 1 | R:R:Y198 | R:R:Y202 | 4.96 | 1 | Yes | Yes | 4 | 7 | 2 | 2 | R:R:I203 | R:R:L276 | 4.28 | 1 | Yes | Yes | 6 | 6 | 2 | 1 | R:R:D279 | R:R:I203 | 2.8 | 1 | Yes | Yes | 4 | 6 | 2 | 2 | R:R:F273 | R:R:T207 | 5.19 | 0 | Yes | Yes | 6 | 5 | 2 | 2 | R:R:L276 | R:R:T207 | 4.42 | 1 | Yes | Yes | 6 | 5 | 1 | 2 | L:L:?1 | R:R:V209 | 2.96 | 1 | Yes | No | 0 | 5 | 0 | 1 | R:R:F210 | R:R:L214 | 2.44 | 1 | Yes | No | 7 | 5 | 1 | 2 | R:R:F210 | R:R:W269 | 9.02 | 1 | Yes | Yes | 7 | 8 | 1 | 1 | R:R:F210 | R:R:F273 | 6.43 | 1 | Yes | Yes | 7 | 6 | 1 | 2 | L:L:?1 | R:R:F210 | 12.1 | 1 | Yes | Yes | 0 | 7 | 0 | 1 | R:R:F265 | R:R:L214 | 3.65 | 0 | No | No | 9 | 5 | 2 | 2 | R:R:F265 | R:R:W269 | 5.01 | 0 | No | Yes | 9 | 8 | 2 | 1 | R:R:N303 | R:R:W269 | 7.91 | 0 | No | Yes | 9 | 8 | 2 | 1 | L:L:?1 | R:R:W269 | 4.53 | 1 | Yes | Yes | 0 | 8 | 0 | 1 | R:R:L272 | R:R:L276 | 2.77 | 1 | No | Yes | 6 | 6 | 1 | 1 | L:L:?1 | R:R:L272 | 6.42 | 1 | Yes | No | 0 | 6 | 0 | 1 | R:R:D279 | R:R:L276 | 4.07 | 1 | Yes | Yes | 4 | 6 | 2 | 1 | L:L:?1 | R:R:L276 | 9.17 | 1 | Yes | Yes | 0 | 6 | 0 | 1 | L:L:?1 | R:R:L297 | 8.25 | 1 | Yes | No | 0 | 5 | 0 | 1 | R:R:A300 | R:R:L272 | 1.58 | 0 | No | No | 7 | 6 | 2 | 1 | R:R:L35 | R:R:Y29 | 1.17 | 0 | No | Yes | 6 | 7 | 2 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 15.00 | Average Number Of Links With An Hub | 7.00 | Average Interaction Strength | 7.54 | Average Nodes In Shell | 34.00 | Average Hubs In Shell | 17.00 | Average Links In Shell | 51.00 | Average Links Mediated by Hubs In Shell | 48.00 |
| ![](/psngpcr/ligands/J8C/J8C_7EVY_L_L_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/J8C/J8C_7EVY_L_L_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7EW1 | A | Lipid | Lysophospholipid (S1P) | S1P5 | Homo sapiens | Siponimod | - | Gi1/Beta1/Gamma2 | 3.4 | 2021-09-29 | 10.1038/s41422-021-00566-x |
![](/psngpcr/ligands/J8C/J8C_7EW1_L_L_1.png)
A 2D representation of the interactions of J8C in 7EW1 colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:K24 | R:R:T22 | 3 | 0 | No | No | 6 | 8 | 1 | 2 | L:L:?1 | R:R:K24 | 4.67 | 0 | Yes | No | 0 | 6 | 0 | 1 | R:R:A88 | R:R:V115 | 3.39 | 0 | No | No | 5 | 5 | 2 | 1 | R:R:L292 | R:R:Y89 | 15.24 | 0 | No | Yes | 5 | 7 | 1 | 2 | R:R:N92 | R:R:R111 | 3.62 | 0 | No | Yes | 5 | 5 | 1 | 2 | L:L:?1 | R:R:N92 | 11.82 | 0 | Yes | No | 0 | 5 | 0 | 1 | R:R:R111 | R:R:W108 | 8 | 6 | Yes | Yes | 5 | 9 | 2 | 2 | R:R:E112 | R:R:W108 | 3.27 | 6 | Yes | Yes | 5 | 9 | 1 | 2 | R:R:L186 | R:R:W108 | 4.56 | 6 | No | Yes | 7 | 9 | 2 | 2 | R:R:W108 | R:R:Y189 | 5.79 | 6 | Yes | Yes | 9 | 5 | 2 | 2 | R:R:E112 | R:R:L186 | 5.3 | 6 | Yes | No | 5 | 7 | 1 | 2 | R:R:E112 | R:R:Y189 | 12.35 | 6 | Yes | Yes | 5 | 5 | 1 | 2 | L:L:?1 | R:R:E112 | 9.65 | 0 | Yes | Yes | 0 | 5 | 0 | 1 | R:R:F116 | R:R:Y189 | 4.13 | 6 | Yes | Yes | 5 | 5 | 1 | 2 | R:R:F116 | R:R:Y193 | 9.28 | 6 | Yes | Yes | 5 | 7 | 1 | 2 | L:L:?1 | R:R:F116 | 7.26 | 0 | Yes | Yes | 0 | 5 | 0 | 1 | R:R:L119 | R:R:W264 | 6.83 | 0 | No | Yes | 7 | 9 | 1 | 2 | L:L:?1 | R:R:L119 | 7.33 | 0 | Yes | No | 0 | 7 | 0 | 1 | R:R:S162 | R:R:T120 | 3.2 | 21 | Yes | No | 7 | 6 | 2 | 1 | L:L:?1 | R:R:T120 | 10.74 | 0 | Yes | No | 0 | 6 | 0 | 1 | R:R:I204 | R:R:V123 | 3.07 | 0 | No | No | 8 | 8 | 2 | 1 | R:R:V123 | R:R:W264 | 2.45 | 0 | No | Yes | 8 | 9 | 1 | 2 | L:L:?1 | R:R:V123 | 7.89 | 0 | Yes | No | 0 | 8 | 0 | 1 | R:R:L186 | R:R:Y189 | 8.21 | 6 | No | Yes | 7 | 5 | 2 | 2 | R:R:Y189 | R:R:Y193 | 5.96 | 6 | Yes | Yes | 5 | 7 | 2 | 2 | L:L:?1 | R:R:C197 | 11.56 | 0 | Yes | No | 0 | 5 | 0 | 1 | R:R:F201 | R:R:V202 | 2.62 | 32 | No | No | 8 | 4 | 1 | 2 | R:R:F201 | R:R:F268 | 9.65 | 32 | No | Yes | 8 | 7 | 1 | 2 | L:L:?1 | R:R:F201 | 4.84 | 0 | Yes | No | 0 | 8 | 0 | 1 | R:R:F268 | R:R:V202 | 3.93 | 32 | Yes | No | 7 | 4 | 2 | 2 | R:R:L267 | R:R:L271 | 5.54 | 0 | No | No | 7 | 6 | 1 | 2 | L:L:?1 | R:R:L267 | 6.42 | 0 | Yes | No | 0 | 7 | 0 | 1 | R:R:L292 | R:R:M296 | 2.83 | 0 | No | No | 5 | 7 | 1 | 2 | L:L:?1 | R:R:L292 | 7.33 | 0 | Yes | No | 0 | 5 | 0 | 1 | L:L:?1 | R:R:A288 | 2.09 | 0 | Yes | No | 0 | 4 | 0 | 1 | R:R:A295 | R:R:L267 | 1.58 | 0 | No | No | 7 | 7 | 2 | 1 | R:R:F116 | R:R:G166 | 1.51 | 6 | Yes | No | 5 | 8 | 1 | 2 | R:R:L124 | R:R:T120 | 1.47 | 0 | No | No | 5 | 6 | 2 | 1 | L:L:?1 | R:R:V115 | 0.99 | 0 | Yes | No | 0 | 5 | 0 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 13.00 | Average Number Of Links With An Hub | 2.00 | Average Interaction Strength | 7.12 | Average Nodes In Shell | 32.00 | Average Hubs In Shell | 11.00 | Average Links In Shell | 39.00 | Average Links Mediated by Hubs In Shell | 31.00 |
| ![](/psngpcr/ligands/J8C/J8C_7EW1_L_L_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/J8C/J8C_7EW1_L_L_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7TD4 | A | Lipid | Lysophospholipid (S1P) | S1P1 | Homo sapiens | Siponimod | - | Gi1/Beta1/Gamma2 | 2.6 | 2022-02-09 | 10.1038/s41467-022-28417-2 |
![](/psngpcr/ligands/J8C/J8C_7TD4_L_L_1.png)
A 2D representation of the interactions of J8C in 7TD4 colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:K34 | R:R:Y29 | 8.36 | 1 | Yes | Yes | 6 | 7 | 1 | 1 | R:R:T109 | R:R:Y29 | 6.24 | 1 | No | Yes | 5 | 7 | 1 | 1 | R:R:Y110 | R:R:Y29 | 6.95 | 0 | No | Yes | 5 | 7 | 2 | 1 | R:R:W117 | R:R:Y29 | 8.68 | 1 | Yes | Yes | 9 | 7 | 2 | 1 | R:R:P196 | R:R:Y29 | 18.08 | 1 | No | Yes | 3 | 7 | 2 | 1 | L:L:?1 | R:R:Y29 | 6.21 | 1 | Yes | Yes | 0 | 7 | 0 | 1 | R:R:K34 | R:R:T32 | 4.5 | 1 | Yes | No | 6 | 8 | 1 | 2 | R:R:P196 | R:R:T32 | 8.74 | 1 | No | No | 3 | 8 | 2 | 2 | R:R:K34 | R:R:P196 | 5.02 | 1 | Yes | No | 6 | 3 | 1 | 2 | L:L:?1 | R:R:K34 | 4.67 | 1 | Yes | Yes | 0 | 6 | 0 | 1 | R:R:M124 | R:R:Y98 | 8.38 | 1 | Yes | Yes | 6 | 6 | 2 | 2 | R:R:E294 | R:R:Y98 | 11.22 | 1 | Yes | Yes | 3 | 6 | 2 | 2 | R:R:L297 | R:R:Y98 | 10.55 | 1 | Yes | Yes | 5 | 6 | 1 | 2 | R:R:N101 | R:R:R120 | 7.23 | 1 | Yes | Yes | 5 | 6 | 1 | 1 | R:R:E121 | R:R:N101 | 3.94 | 1 | Yes | Yes | 5 | 5 | 1 | 1 | R:R:M124 | R:R:N101 | 4.21 | 1 | Yes | Yes | 6 | 5 | 2 | 1 | L:L:?1 | R:R:N101 | 13.64 | 1 | Yes | Yes | 0 | 5 | 0 | 1 | R:R:G106 | R:R:S105 | 3.71 | 0 | No | No | 4 | 4 | 2 | 1 | L:L:?1 | R:R:S105 | 4.97 | 1 | Yes | No | 0 | 4 | 0 | 1 | R:R:R120 | R:R:T109 | 6.47 | 1 | Yes | No | 6 | 5 | 1 | 1 | L:L:?1 | R:R:T109 | 3.9 | 1 | Yes | No | 0 | 5 | 0 | 1 | R:R:L112 | R:R:R120 | 3.64 | 0 | No | Yes | 5 | 6 | 2 | 1 | R:R:R120 | R:R:W117 | 7 | 1 | Yes | Yes | 6 | 9 | 1 | 2 | R:R:E121 | R:R:W117 | 15.27 | 1 | Yes | Yes | 5 | 9 | 1 | 2 | R:R:W117 | R:R:Y198 | 4.82 | 1 | Yes | Yes | 9 | 4 | 2 | 2 | R:R:E121 | R:R:R120 | 13.96 | 1 | Yes | Yes | 5 | 6 | 1 | 1 | L:L:?1 | R:R:R120 | 5.63 | 1 | Yes | Yes | 0 | 6 | 0 | 1 | R:R:E121 | R:R:L195 | 9.28 | 1 | Yes | Yes | 5 | 3 | 1 | 1 | R:R:E121 | R:R:Y198 | 5.61 | 1 | Yes | Yes | 5 | 4 | 1 | 2 | L:L:?1 | R:R:E121 | 11.41 | 1 | Yes | Yes | 0 | 5 | 0 | 1 | R:R:L297 | R:R:M124 | 4.24 | 1 | Yes | Yes | 5 | 6 | 1 | 2 | R:R:F125 | R:R:L195 | 3.65 | 1 | Yes | Yes | 5 | 3 | 1 | 1 | R:R:F125 | R:R:Y198 | 11.35 | 1 | Yes | Yes | 5 | 4 | 1 | 2 | R:R:F125 | R:R:Y202 | 7.22 | 1 | Yes | Yes | 5 | 7 | 1 | 2 | R:R:C206 | R:R:F125 | 4.19 | 1 | No | Yes | 6 | 5 | 1 | 1 | L:L:?1 | R:R:F125 | 26.62 | 1 | Yes | Yes | 0 | 5 | 0 | 1 | R:R:L128 | R:R:W269 | 9.11 | 1 | No | Yes | 6 | 8 | 1 | 1 | L:L:?1 | R:R:L128 | 6.42 | 1 | Yes | No | 0 | 6 | 0 | 1 | R:R:S129 | R:R:S171 | 6.52 | 0 | No | No | 6 | 8 | 1 | 2 | L:L:?1 | R:R:S129 | 8.95 | 1 | Yes | No | 0 | 6 | 0 | 1 | R:R:L213 | R:R:V132 | 5.96 | 0 | No | Yes | 8 | 7 | 2 | 1 | R:R:F265 | R:R:V132 | 3.93 | 1 | Yes | Yes | 9 | 7 | 2 | 1 | R:R:V132 | R:R:W269 | 4.9 | 1 | Yes | Yes | 7 | 8 | 1 | 1 | L:L:?1 | R:R:V132 | 3.95 | 1 | Yes | Yes | 0 | 7 | 0 | 1 | R:R:L195 | R:R:V194 | 4.47 | 1 | Yes | Yes | 3 | 4 | 1 | 1 | R:R:L276 | R:R:V194 | 4.47 | 1 | No | Yes | 6 | 4 | 1 | 1 | R:R:D279 | R:R:V194 | 7.3 | 1 | Yes | Yes | 4 | 4 | 2 | 1 | L:L:?1 | R:R:V194 | 4.93 | 1 | Yes | Yes | 0 | 4 | 0 | 1 | R:R:L195 | R:R:Y198 | 12.89 | 1 | Yes | Yes | 3 | 4 | 1 | 2 | L:L:?1 | R:R:L195 | 9.17 | 1 | Yes | Yes | 0 | 3 | 0 | 1 | R:R:Y198 | R:R:Y202 | 4.96 | 1 | Yes | Yes | 4 | 7 | 2 | 2 | R:R:C206 | R:R:Y202 | 9.41 | 1 | No | Yes | 6 | 7 | 1 | 2 | R:R:F205 | R:R:V209 | 3.93 | 0 | No | No | 5 | 5 | 2 | 1 | L:L:?1 | R:R:C206 | 5.25 | 1 | Yes | No | 0 | 6 | 0 | 1 | L:L:?1 | R:R:V209 | 3.95 | 1 | Yes | No | 0 | 5 | 0 | 1 | R:R:F210 | R:R:F265 | 4.29 | 1 | Yes | Yes | 7 | 9 | 1 | 2 | R:R:F210 | R:R:W269 | 14.03 | 1 | Yes | Yes | 7 | 8 | 1 | 1 | R:R:F210 | R:R:F273 | 7.5 | 1 | Yes | Yes | 7 | 6 | 1 | 2 | L:L:?1 | R:R:F210 | 8.07 | 1 | Yes | Yes | 0 | 7 | 0 | 1 | R:R:F265 | R:R:W269 | 7.02 | 1 | Yes | Yes | 9 | 8 | 2 | 1 | R:R:F265 | R:R:N303 | 8.46 | 1 | Yes | Yes | 9 | 9 | 2 | 2 | R:R:A300 | R:R:W269 | 7.78 | 0 | No | Yes | 7 | 8 | 2 | 1 | R:R:N303 | R:R:W269 | 9.04 | 1 | Yes | Yes | 9 | 8 | 2 | 1 | L:L:?1 | R:R:W269 | 5.28 | 1 | Yes | Yes | 0 | 8 | 0 | 1 | R:R:L272 | R:R:L276 | 6.92 | 0 | No | No | 6 | 6 | 2 | 1 | L:L:?1 | R:R:L276 | 6.42 | 1 | Yes | No | 0 | 6 | 0 | 1 | R:R:E294 | R:R:L297 | 5.3 | 1 | Yes | Yes | 3 | 5 | 2 | 1 | L:L:?1 | R:R:L297 | 12.83 | 1 | Yes | Yes | 0 | 5 | 0 | 1 | R:R:A293 | R:R:V194 | 3.39 | 0 | No | Yes | 4 | 4 | 2 | 1 | R:R:F291 | R:R:K34 | 2.48 | 0 | No | Yes | 1 | 6 | 2 | 1 | R:R:L104 | R:R:R120 | 2.43 | 0 | No | Yes | 4 | 6 | 2 | 1 | R:R:E121 | R:R:G122 | 1.64 | 1 | Yes | No | 5 | 6 | 1 | 2 | R:R:T208 | R:R:V209 | 1.59 | 0 | No | No | 4 | 5 | 2 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 19.00 | Average Number Of Links With An Hub | 12.00 | Average Interaction Strength | 8.01 | Average Nodes In Shell | 45.00 | Average Hubs In Shell | 23.00 | Average Links In Shell | 73.00 | Average Links Mediated by Hubs In Shell | 67.00 |
| ![](/psngpcr/ligands/J8C/J8C_7TD4_L_L_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/J8C/J8C_7TD4_L_L_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
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