CodeLSC
Name(4R,7R,18E)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide
Synonyms
Identifiertrimethyl-[2-[[(2R)-3-[(E)-octadec-9-enoyl]oxy-2-oxidanyl-propoxy]-oxidanyl-phosphoryl]oxyethyl]azanium
FormulaC26 H53 N O7 P
Molecular Weight522.675
SMILESCCCCCCCC/C=C/CCCCCCCC(=O)OC[C@H](CO[P@](=O)(O)OCC[N+](C)(C)C)O
PubChem5313986
Formal Charge1
Total Atoms88
Total Chiral Atoms1
Total Bonds87
Total Aromatic Bonds0
Networks1
 missing image

This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7XZ5 A Lipid GPR119 GPR119 Homo sapiens Lysophosphatidylcholine - Gs/Beta1/Gamma2 3.1 2022-08-24 10.1038/s41594-022-00816-5

A 2D representation of the interactions of LSC in 7XZ5
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:R262 R:R:S3 3.95 0 Yes No 3 6 1 2
R:R:F7 R:R:L11 8.53 4 Yes Yes 5 6 2 2
R:R:F7 R:R:Q65 9.37 4 Yes Yes 5 4 2 1
R:R:F7 R:R:R262 11.76 4 Yes Yes 5 3 2 1
R:R:F7 R:R:W265 5.01 4 Yes Yes 5 3 2 1
R:R:F7 R:R:L266 4.87 4 Yes No 5 5 2 2
R:R:G8 R:R:L11 3.42 0 No Yes 4 6 2 2
R:R:G8 R:R:Q65 3.29 0 No Yes 4 4 2 1
R:R:L11 R:R:W265 4.56 4 Yes Yes 6 3 2 1
R:R:I58 R:R:W265 3.52 4 No Yes 7 3 2 1
R:R:I58 R:R:V269 3.07 4 No No 7 6 2 2
R:R:D64 R:R:Q65 3.92 0 No Yes 4 4 2 1
L:L:?1 R:R:Q65 7.28 4 Yes Yes 0 4 0 1
R:R:A89 R:R:W238 5.19 4 No Yes 6 8 1 1
L:L:?1 R:R:A89 4.31 4 Yes No 0 6 0 1
R:R:A90 R:R:S133 3.42 0 No Yes 7 8 1 2
L:L:?1 R:R:A90 3.23 4 Yes No 0 7 0 1
R:R:F174 R:R:V93 3.93 0 Yes No 8 7 2 1
L:L:?1 R:R:V93 5.09 4 Yes No 0 7 0 1
R:R:L94 R:R:S133 3 0 No Yes 5 8 1 2
L:L:?1 R:R:L94 4.73 4 Yes No 0 5 0 1
R:R:A159 R:R:S156 3.42 0 No No 4 4 2 1
R:R:E261 R:R:S156 10.06 4 No No 4 4 1 1
L:L:?1 R:R:S156 14.37 4 Yes No 0 4 0 1
R:R:F157 R:R:F158 10.72 4 Yes Yes 4 3 1 2
R:R:F157 R:R:F161 6.43 4 Yes Yes 4 4 1 2
R:R:F157 R:R:F165 5.36 4 Yes Yes 4 6 1 2
L:L:?1 R:R:F157 9.99 4 Yes Yes 0 4 0 1
R:R:F158 R:R:F241 4.29 4 Yes No 3 6 2 1
R:R:F158 R:R:L260 9.74 4 Yes No 3 4 2 2
R:R:E261 R:R:F158 15.16 4 No Yes 4 3 1 2
R:R:F161 R:R:F165 4.29 4 Yes Yes 4 6 2 2
L:L:?1 R:R:L169 6.62 4 Yes No 0 6 0 1
R:R:F174 R:R:W238 5.01 0 Yes Yes 8 8 2 1
R:R:S237 R:R:W238 6.18 0 No Yes 7 8 2 1
R:R:G268 R:R:W238 9.85 0 No Yes 7 8 2 1
L:L:?1 R:R:W238 14.79 4 Yes Yes 0 8 0 1
R:R:F241 R:R:L260 9.74 4 No No 6 4 1 2
L:L:?1 R:R:F241 4.99 4 Yes No 0 6 0 1
L:L:?1 R:R:E261 14.49 4 Yes No 0 4 0 1
R:R:R262 R:R:Y263 3.09 0 Yes No 3 4 1 2
L:L:?1 R:R:R262 9.13 4 Yes Yes 0 3 0 1
R:R:L266 R:R:W265 5.69 4 No Yes 5 3 2 1
R:R:V269 R:R:W265 3.68 4 No Yes 6 3 2 1
L:L:?1 R:R:W265 31.92 4 Yes Yes 0 3 0 1
R:R:L94 R:R:V132 2.98 0 No No 5 3 1 2
L:L:?1 R:R:G173 2.34 4 Yes No 0 6 0 1
StatisticsValue
Average Number Of Links14.00
Average Number Of Links With An Hub5.00
Average Interaction Strength9.52
Average Nodes In Shell34.00
Average Hubs In Shell13.00
Average Links In Shell47.00
Average Links Mediated by Hubs In Shell42.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links14.00
Average Number Of Links With An Hub5.00
Average Interaction Strength9.52
Average Nodes In Shell34.00
Average Hubs In Shell13.00
Average Links In Shell47.00
Average Links Mediated by Hubs In Shell42.00

missing image


Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

missing image


Location of the nodes interacting with this ligand

(Click to enlarge 🔍)