CodeORN
NameOrnithine
SynonymsOrnithinum
Identifier(2S)-2,5-bis(azanyl)pentanoic acid
FormulaC5 H12 N2 O2
Molecular Weight132.161
SMILESC(C[C@@H](C(=O)O)N)CN
PubChem88747248
Formal Charge0
Total Atoms21
Total Chiral Atoms1
Total Bonds20
Total Aromatic Bonds0
Networks2
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This ligand is also present in the following 2 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
6C1Q A Peptide Complement peptide C5a1 Homo sapiens PMX53 NDT9513727 - 2.9 2018-05-30 10.1038/s41594-018-0067-z

A 2D representation of the interactions of ORN in 6C1Q
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:S95 R:R:W102 4.94 1 No Yes 4 8 2 2
L:L:?4 R:R:S95 6.97 1 Yes No 0 4 1 2
L:L:?4 R:R:H100 3.58 1 Yes No 0 4 1 2
L:L:?4 R:R:W102 3.17 1 Yes Yes 0 8 1 2
R:R:G189 R:R:R175 3 1 Yes Yes 4 5 1 2
L:L:?4 R:R:R175 10.15 1 Yes Yes 0 5 1 2
L:L:F1 R:R:R178 28.86 1 Yes No 0 2 1 2
L:L:F1 R:R:L187 3.65 1 Yes No 0 4 1 2
L:L:F1 R:R:G189 3.01 1 Yes Yes 0 4 1 1
L:L:?2 R:R:G189 3.18 1 Yes Yes 0 4 0 1
L:L:?4 R:R:G189 3.18 1 Yes Yes 0 4 1 1
R:R:V190 R:R:Y192 6.31 0 No Yes 5 5 1 2
L:L:?2 R:R:V190 4.16 1 Yes No 0 5 0 1
L:L:?2 L:L:F1 13.59 1 Yes Yes 0 0 0 1
L:L:?2 L:L:P3 15.27 1 Yes No 0 0 0 1
L:L:?2 L:L:?4 3.59 1 Yes Yes 0 0 0 1
L:L:?4 L:L:P3 4.57 1 Yes No 0 0 1 1
L:L:?4 L:L:W5 17.98 1 Yes Yes 0 0 1 2
R:R:K279 R:R:L276 2.82 0 No No 4 3 1 2
L:L:?4 R:R:I96 2.65 1 Yes Yes 0 5 1 2
L:L:?2 R:R:K279 2.62 1 Yes No 0 4 0 1
StatisticsValue
Average Number Of Links6.00
Average Number Of Links With An Hub3.00
Average Interaction Strength7.07
Average Nodes In Shell17.00
Average Hubs In Shell9.00
Average Links In Shell21.00
Average Links Mediated by Hubs In Shell20.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
6C1R A Peptide Complement peptide C5a1 Homo sapiens PMX53 Avacopan; Na - 2.2 2018-05-30 10.1038/s41594-018-0067-z

A 2D representation of the interactions of ORN in 6C1R
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?4 R:R:S95 5.58 0 Yes No 0 4 1 2
L:L:?4 R:R:I96 3.98 0 Yes Yes 0 5 1 2
L:L:?4 R:R:R175 10.15 0 Yes Yes 0 5 1 2
L:L:F1 R:R:R178 24.59 3 Yes No 0 2 1 2
L:L:F1 R:R:L187 3.65 3 Yes No 0 4 1 2
L:L:?4 R:R:G189 6.35 0 Yes No 0 4 1 2
R:R:V190 R:R:Y192 5.05 0 No Yes 5 5 1 2
L:L:?2 R:R:V190 6.93 3 Yes No 0 5 0 1
R:R:F275 R:R:K279 7.44 9 Yes No 3 4 2 1
L:L:?2 R:R:K279 6.56 3 Yes No 0 4 0 1
L:L:?2 L:L:F1 19.26 3 Yes Yes 0 0 0 1
L:L:F1 L:L:P3 4.33 3 Yes No 0 0 1 1
L:L:?2 L:L:P3 15.27 3 Yes No 0 0 0 1
L:L:?2 L:L:?4 4.78 3 Yes Yes 0 0 0 1
L:L:?4 L:L:W5 21.15 0 Yes Yes 0 0 1 2
L:L:?4 R:R:H100 3.58 0 Yes No 0 4 1 2
StatisticsValue
Average Number Of Links5.00
Average Number Of Links With An Hub2.00
Average Interaction Strength10.56
Average Nodes In Shell16.00
Average Hubs In Shell8.00
Average Links In Shell16.00
Average Links Mediated by Hubs In Shell16.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links5.50
Average Number Of Links With An Hub2.50
Average Interaction Strength8.81
Average Nodes In Shell16.50
Average Hubs In Shell8.50
Average Links In Shell18.50
Average Links Mediated by Hubs In Shell18.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

missing image


Location of the nodes interacting with this ligand

(Click to enlarge 🔍)