CodePHA
NamePHENYLALANINAL
Synonyms
Identifier
FormulaC9 H11 N O
Molecular Weight149.19
SMILES
PubChem446207
Formal Charge0
Total Atoms22
Total Chiral Atoms1
Total Bonds22
Total Aromatic Bonds6
Networks4
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This ligand is also present in the following 4 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8ZCJ A Peptide Somatostatin SST5 Homo Sapiens Pasireotide - Gi1/Beta1/Gamma1 3.09 2024-07-10 doi.org/10.1038/s41401-024-01314-8

A 2D representation of the interactions of PHA in 8ZCJ
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?1 L:L:?6 20.99 1 Yes No 0 0 2 1
L:L:?1 R:R:N268 7.61 1 Yes Yes 0 5 2 2
L:L:?1 R:R:N271 6.53 1 Yes No 0 4 2 2
L:L:?5 L:L:Y4 3.65 1 Yes No 0 0 0 1
L:L:Y4 R:R:Q99 10.15 1 No No 0 4 1 2
L:L:Y4 R:R:T185 16.23 1 No Yes 0 4 1 2
L:L:?5 L:L:?6 31.44 1 Yes No 0 0 0 1
L:L:?5 R:R:L276 5.39 1 Yes Yes 0 1 0 1
L:L:?5 R:R:S282 5.85 1 Yes No 0 5 0 1
L:L:?5 R:R:Y286 13.69 1 Yes No 0 4 0 1
L:L:?6 R:R:N271 8.76 1 No No 0 4 1 2
R:R:Q99 R:R:T185 4.25 1 No Yes 4 4 2 2
R:R:N268 R:R:V267 4.43 1 Yes No 5 5 2 2
R:R:V267 R:R:Y286 11.36 1 No No 5 4 2 1
R:R:N268 R:R:Y286 4.65 1 Yes No 5 4 2 1
R:R:L276 R:R:N271 6.87 1 Yes No 1 4 1 2
R:R:L276 R:R:S282 7.51 1 Yes No 1 5 1 1
R:R:A283 R:R:F287 4.16 0 No No 4 3 1 2
L:L:?5 R:R:A283 2.45 1 Yes No 0 4 0 1
L:L:?5 R:R:Q278 2.07 1 Yes No 0 1 0 1
R:R:L276 R:R:P277 1.64 1 Yes No 1 3 1 2
StatisticsValue
Average Number Of Links7.00
Average Number Of Links With An Hub1.00
Average Interaction Strength9.22
Average Nodes In Shell16.00
Average Hubs In Shell5.00
Average Links In Shell21.00
Average Links Mediated by Hubs In Shell17.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
9IK8 A Peptide Somatostatin SST1 Homo Sapiens SST analogue - Gi1/Beta1/Gamma2 2.82 2025-04-30 doi.org/10.1016/j.apsb.2025.03.043

A 2D representation of the interactions of PHA in 9IK8
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?1 L:L:K2 26.86 2 Yes Yes 0 0 2 2
L:L:?1 L:L:?6 16.88 2 Yes Yes 0 0 2 1
L:L:?3 L:L:K2 19.67 2 Yes Yes 0 0 1 2
L:L:K2 R:R:L114 4.23 2 Yes Yes 0 6 2 2
L:L:?3 L:L:?4 16.98 2 Yes Yes 0 0 1 0
L:L:?3 R:R:L114 28.39 2 Yes Yes 0 6 1 2
L:L:?3 R:R:S117 8.62 2 Yes No 0 6 1 2
L:L:?3 R:R:L134 4.54 2 Yes No 0 5 1 2
L:L:?3 R:R:D137 13.36 2 Yes No 0 6 1 2
L:L:?3 R:R:N209 3.38 2 Yes No 0 5 1 2
L:L:?3 R:R:Y313 3.85 2 Yes Yes 0 7 1 2
L:L:?4 L:L:?5 57.37 2 Yes No 0 0 0 1
L:L:?4 L:L:?6 10.57 2 Yes Yes 0 0 0 1
L:L:?4 R:R:A302 7.44 2 Yes No 0 4 0 1
L:L:?4 R:R:S305 10.63 2 Yes No 0 4 0 1
L:L:?5 L:L:?6 24.21 2 No Yes 0 0 1 1
L:L:?5 R:R:E298 28.67 2 No No 0 1 1 2
L:L:?6 R:R:L220 15.67 2 Yes No 0 5 1 2
L:L:?6 R:R:V224 12.04 2 Yes No 0 5 1 2
L:L:?6 R:R:V295 9.63 2 Yes No 0 4 1 2
R:R:D137 R:R:Y313 4.6 2 No Yes 6 7 2 2
StatisticsValue
Average Number Of Links5.00
Average Number Of Links With An Hub2.00
Average Interaction Strength20.60
Average Nodes In Shell18.00
Average Hubs In Shell7.00
Average Links In Shell21.00
Average Links Mediated by Hubs In Shell20.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links6.00
Average Number Of Links With An Hub1.50
Average Interaction Strength14.62
Average Nodes In Shell17.00
Average Hubs In Shell6.00
Average Links In Shell21.00
Average Links Mediated by Hubs In Shell18.50

missing image


Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

missing image


Location of the nodes interacting with this ligand

(Click to enlarge 🔍)