CodePPI
NamePropanoic acid
Synonyms
  • Propionic acid
  • Sodium propionate
  • Propanoic acid
Identifier
FormulaC3 H6 O2
Molecular Weight74.079
SMILES
PubChem1032
Formal Charge0
Total Atoms11
Total Chiral Atoms0
Total Bonds10
Total Aromatic Bonds0
Networks2
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This ligand is also present in the following 2 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8F76 O1 Odorant receptors Odorant family 51 OR51E2 Homo Sapiens Propanoic acid - Gs/Beta1/Gamma2 3.1 2023-03-22 doi.org/10.1038/s41586-023-05798-y

A 2D representation of the interactions of PPI in 8F76
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?1 R:R:H104 16.9 4 Yes Yes 0 4 0 1
L:L:?1 R:R:L158 6.62 4 Yes Yes 0 4 0 1
L:L:?1 R:R:H180 18.44 4 Yes Yes 0 6 0 1
L:L:?1 R:R:Q181 14.32 4 Yes Yes 0 4 0 1
L:L:?1 R:R:G198 8.18 4 Yes No 0 4 0 1
L:L:?1 R:R:I202 10.24 4 Yes No 0 4 0 1
L:L:?1 R:R:R262 11.62 4 Yes Yes 0 4 0 1
R:R:I162 R:R:M100 5.83 4 No No 4 4 2 2
R:R:H180 R:R:M100 5.25 4 Yes No 6 4 1 2
R:R:H104 R:R:L158 5.14 4 Yes Yes 4 4 1 1
R:R:H104 R:R:V179 5.54 4 Yes Yes 4 8 1 2
R:R:H104 R:R:Q181 7.42 4 Yes Yes 4 4 1 1
R:R:F155 R:R:L158 8.53 4 Yes Yes 5 4 2 1
R:R:F155 R:R:M206 3.73 4 Yes Yes 5 3 2 2
R:R:H180 R:R:L158 16.71 4 Yes Yes 6 4 1 1
R:R:L158 R:R:Y197 3.52 4 Yes No 4 4 1 2
R:R:H180 R:R:I162 7.95 4 Yes No 6 4 1 2
R:R:I162 R:R:N194 4.25 4 No Yes 4 6 2 2
R:R:Q181 R:R:V179 10.03 4 Yes Yes 4 8 1 2
R:R:H180 R:R:N194 8.93 4 Yes Yes 6 6 1 2
R:R:H180 R:R:R262 3.39 4 Yes Yes 6 4 1 1
R:R:L257 R:R:Q181 3.99 4 Yes Yes 5 4 2 1
R:R:Q181 R:R:S258 4.33 4 Yes No 4 7 1 2
R:R:H261 R:R:Q181 12.36 4 Yes Yes 7 4 2 1
R:R:M184 R:R:R262 7.44 0 No Yes 4 4 2 1
R:R:R262 R:R:V195 6.54 4 Yes No 4 5 1 2
R:R:L199 R:R:R262 6.07 0 No Yes 4 4 2 1
R:R:I202 R:R:M206 4.37 0 No Yes 4 3 1 2
R:R:I202 R:R:S258 9.29 0 No No 4 7 1 2
R:R:H261 R:R:L257 5.14 4 Yes Yes 7 5 2 2
R:R:F263 R:R:R262 7.48 0 No Yes 5 4 2 1
R:R:L158 R:R:P159 1.64 4 Yes No 4 4 1 2
StatisticsValue
Average Number Of Links7.00
Average Number Of Links With An Hub5.00
Average Interaction Strength12.33
Average Nodes In Shell23.00
Average Hubs In Shell12.00
Average Links In Shell32.00
Average Links Mediated by Hubs In Shell30.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links7.00
Average Number Of Links With An Hub5.00
Average Interaction Strength12.33
Average Nodes In Shell23.00
Average Hubs In Shell12.00
Average Links In Shell32.50
Average Links Mediated by Hubs In Shell30.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)