CodeQD7
Name(R)-(3-aminopropyl)methylphosphinic acid
Synonyms
Identifier3-azanylpropyl(methyl)phosphinic acid
FormulaC4 H12 N O2 P
Molecular Weight137.117
SMILESCP(=O)(CCCN)O
PubChem28559746
Formal Charge0
Total Atoms20
Total Chiral Atoms0
Total Bonds19
Total Aromatic Bonds0
Networks2
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This ligand is also present in the following 2 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
6UO8 C Aminoacid GABAB GABAB1; GABAB2 Homo sapiens SKF97541 GS39783 - 3.63 2020-06-10 10.1038/s41586-020-2408-4

A 2D representation of the interactions of QD7 in 6UO8
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:P177 R:R:W182 2.7 0 No Yes 7 6 2 1
R:R:G181 R:R:Y367 4.35 0 No Yes 5 7 2 1
R:R:G184 R:R:W182 5.63 0 No Yes 5 6 2 1
R:R:W182 R:R:W395 4.69 1 Yes Yes 6 5 1 1
R:R:E466 R:R:W182 6.54 1 Yes Yes 5 6 1 1
L:L:?1001 R:R:W182 14.58 1 Yes Yes 0 6 0 1
R:R:C246 R:R:Y367 2.69 0 No Yes 7 7 2 1
R:R:S247 R:R:S271 4.89 1 No No 9 9 1 2
R:R:S247 R:R:V318 8.08 1 No No 9 5 1 1
L:L:?1001 R:R:S247 4.8 1 Yes No 0 9 0 1
R:R:G268 R:R:H287 3.18 0 No Yes 7 7 2 1
R:R:H287 R:R:S270 6.97 1 Yes No 7 7 1 1
R:R:A290 R:R:S270 3.42 0 No No 8 7 2 1
L:L:?1001 R:R:S270 6.41 1 Yes No 0 7 0 1
R:R:S271 R:R:V318 4.85 1 No No 9 5 2 1
R:R:H287 R:R:P288 12.2 1 Yes No 7 6 1 2
R:R:H287 R:R:M429 3.94 1 Yes No 7 4 1 2
R:R:E466 R:R:H287 2.46 1 Yes Yes 5 7 1 1
R:R:H287 R:R:L469 3.86 1 Yes Yes 7 6 1 2
L:L:?1001 R:R:H287 5.49 1 Yes Yes 0 7 0 1
R:R:M429 R:R:P288 6.71 1 No No 4 6 2 2
L:L:?1001 R:R:V318 3.18 1 Yes No 0 5 0 1
R:R:F319 R:R:Y367 5.16 0 No Yes 7 7 2 1
L:L:?1001 R:R:Y367 5 1 Yes Yes 0 7 0 1
R:R:I393 R:R:W395 5.87 1 No Yes 5 5 2 1
R:R:I393 R:R:Y396 2.42 1 No Yes 5 5 2 2
R:R:W395 R:R:Y396 3.86 1 Yes Yes 5 5 1 2
L:L:?1001 R:R:W395 4.86 1 Yes Yes 0 5 0 1
R:R:L469 R:R:M429 5.65 1 Yes No 6 4 2 2
R:R:E466 R:R:Q465 2.55 1 Yes No 5 4 1 2
R:R:E466 R:R:L469 2.65 1 Yes Yes 5 6 1 2
L:L:?1001 R:R:E466 5.65 1 Yes Yes 0 5 0 1
StatisticsValue
Average Number Of Links8.00
Average Number Of Links With An Hub5.00
Average Interaction Strength6.25
Average Nodes In Shell23.00
Average Hubs In Shell8.00
Average Links In Shell32.00
Average Links Mediated by Hubs In Shell27.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
6UO9 C Aminoacid GABAB GABAB1; GABAB2 Homo sapiens SKF97541 - - 4.8 2020-06-10 10.1038/s41586-020-2408-4

A 2D representation of the interactions of QD7 in 6UO9
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:G184 R:R:W182 5.63 0 No Yes 5 6 2 1
R:R:W182 R:R:W395 6.56 1 Yes Yes 6 5 1 1
R:R:E466 R:R:W182 3.27 1 Yes Yes 5 6 1 1
L:L:?1001 R:R:W182 12.15 1 Yes Yes 0 6 0 1
R:R:G184 R:R:G463 2.11 0 No No 5 4 2 2
R:R:S247 R:R:S250 1.63 1 No No 9 8 1 2
R:R:S247 R:R:S269 1.63 1 No Yes 9 8 1 1
L:L:?1001 R:R:S247 11.21 1 Yes No 0 9 0 1
R:R:S250 R:R:S269 6.52 1 No Yes 8 8 2 1
R:R:G268 R:R:S266 1.86 0 No Yes 7 8 2 2
R:R:S266 R:R:S269 6.52 1 Yes Yes 8 8 2 1
R:R:R285 R:R:S266 2.64 1 Yes Yes 9 8 2 2
R:R:G268 R:R:H287 4.77 0 No Yes 7 7 2 1
R:R:R285 R:R:S269 2.64 1 Yes Yes 9 8 2 1
L:L:?1001 R:R:S269 1.6 1 Yes Yes 0 8 0 1
R:R:H287 R:R:S270 5.58 1 Yes No 7 7 1 1
R:R:A290 R:R:S270 3.42 0 No No 8 7 2 1
L:L:?1001 R:R:S270 1.6 1 Yes No 0 7 0 1
R:R:S271 R:R:V318 3.23 0 Yes Yes 9 5 2 1
R:R:H287 R:R:P288 7.63 1 Yes Yes 7 6 1 2
R:R:H287 R:R:M429 2.63 1 Yes Yes 7 4 1 2
R:R:H287 R:R:L469 3.86 1 Yes Yes 7 6 1 2
L:L:?1001 R:R:H287 4.11 1 Yes Yes 0 7 0 1
R:R:M429 R:R:P288 6.71 1 Yes Yes 4 6 2 2
R:R:L469 R:R:P288 1.64 1 Yes Yes 6 6 2 2
R:R:T316 R:R:V318 3.17 1 No Yes 5 5 2 1
R:R:F319 R:R:T316 2.59 1 No No 7 5 2 2
R:R:F319 R:R:V318 7.87 1 No Yes 7 5 2 1
L:L:?1001 R:R:V318 1.59 1 Yes Yes 0 5 0 1
R:R:I393 R:R:W395 4.7 0 No Yes 5 5 2 1
R:R:W395 R:R:Y396 4.82 1 Yes No 5 5 1 2
R:R:E426 R:R:W395 2.18 0 No Yes 6 5 2 1
L:L:?1001 R:R:W395 29.16 1 Yes Yes 0 5 0 1
R:R:L469 R:R:M429 5.65 1 Yes Yes 6 4 2 2
R:R:E466 R:R:G463 1.64 1 Yes No 5 4 1 2
R:R:E466 R:R:Q465 2.55 1 Yes No 5 4 1 2
R:R:E466 R:R:L469 2.65 1 Yes Yes 5 6 1 2
L:L:?1001 R:R:E466 4.24 1 Yes Yes 0 5 0 1
StatisticsValue
Average Number Of Links8.00
Average Number Of Links With An Hub6.00
Average Interaction Strength8.21
Average Nodes In Shell26.00
Average Hubs In Shell13.00
Average Links In Shell38.00
Average Links Mediated by Hubs In Shell34.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links8.00
Average Number Of Links With An Hub5.50
Average Interaction Strength7.23
Average Nodes In Shell24.50
Average Hubs In Shell10.50
Average Links In Shell35.00
Average Links Mediated by Hubs In Shell30.50

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

missing image


Location of the nodes interacting with this ligand

(Click to enlarge 🔍)