CodeQD7
Name(R)-(3-aminopropyl)methylphosphinic acid
Synonyms
Identifier
FormulaC4 H12 N O2 P
Molecular Weight137.117
SMILES
PubChem5230
Formal Charge0
Total Atoms20
Total Chiral Atoms0
Total Bonds19
Total Aromatic Bonds0
Networks2
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This ligand is also present in the following 2 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
6UO8 C Aminoacid GABAB GABAB1; GABAB2 Homo Sapiens SKF97541 GS39783 - 3.63 2020-06-10 doi.org/10.1038/s41586-020-2408-4

A 2D representation of the interactions of QD7 in 6UO8
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?1001 R:R:W182 14.58 1 Yes Yes 0 6 0 1
L:L:?1001 R:R:S247 4.8 1 Yes No 0 9 0 1
L:L:?1001 R:R:S270 6.41 1 Yes No 0 7 0 1
L:L:?1001 R:R:H287 5.49 1 Yes Yes 0 7 0 1
L:L:?1001 R:R:V318 3.18 1 Yes No 0 5 0 1
L:L:?1001 R:R:Y367 5 1 Yes Yes 0 7 0 1
L:L:?1001 R:R:W395 4.86 1 Yes Yes 0 5 0 1
L:L:?1001 R:R:E466 5.65 1 Yes Yes 0 5 0 1
R:R:P177 R:R:W182 2.7 0 No Yes 7 6 2 1
R:R:G181 R:R:Y367 4.35 0 No Yes 5 7 2 1
R:R:G184 R:R:W182 5.63 0 No Yes 5 6 2 1
R:R:W182 R:R:W395 4.69 1 Yes Yes 6 5 1 1
R:R:E466 R:R:W182 6.54 1 Yes Yes 5 6 1 1
R:R:C246 R:R:Y367 2.69 0 No Yes 7 7 2 1
R:R:S247 R:R:S271 4.89 1 No No 9 9 1 2
R:R:S247 R:R:V318 8.08 1 No No 9 5 1 1
R:R:G268 R:R:H287 3.18 0 No Yes 7 7 2 1
R:R:H287 R:R:S270 6.97 1 Yes No 7 7 1 1
R:R:A290 R:R:S270 3.42 0 No No 8 7 2 1
R:R:S271 R:R:V318 4.85 1 No No 9 5 2 1
R:R:H287 R:R:P288 12.2 1 Yes No 7 6 1 2
R:R:H287 R:R:M429 3.94 1 Yes No 7 4 1 2
R:R:E466 R:R:H287 2.46 1 Yes Yes 5 7 1 1
R:R:H287 R:R:L469 3.86 1 Yes Yes 7 6 1 2
R:R:M429 R:R:P288 6.71 1 No No 4 6 2 2
R:R:F319 R:R:Y367 5.16 0 No Yes 7 7 2 1
R:R:I393 R:R:W395 5.87 1 No Yes 5 5 2 1
R:R:I393 R:R:Y396 2.42 1 No Yes 5 5 2 2
R:R:W395 R:R:Y396 3.86 1 Yes Yes 5 5 1 2
R:R:L469 R:R:M429 5.65 1 Yes No 6 4 2 2
R:R:E466 R:R:Q465 2.55 1 Yes No 5 4 1 2
R:R:E466 R:R:L469 2.65 1 Yes Yes 5 6 1 2
StatisticsValue
Average Number Of Links8.00
Average Number Of Links With An Hub5.00
Average Interaction Strength6.25
Average Nodes In Shell23.00
Average Hubs In Shell8.00
Average Links In Shell32.00
Average Links Mediated by Hubs In Shell27.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
6UO9 C Aminoacid GABAB GABAB1; GABAB2 Homo Sapiens SKF97541 - - 4.8 2020-06-10 doi.org/10.1038/s41586-020-2408-4

A 2D representation of the interactions of QD7 in 6UO9
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?1001 R:R:W182 12.15 8 Yes Yes 0 6 0 1
L:L:?1001 R:R:S247 11.21 8 Yes No 0 9 0 1
L:L:?1001 R:R:H287 4.11 8 Yes Yes 0 7 0 1
L:L:?1001 R:R:W395 29.16 8 Yes Yes 0 5 0 1
L:L:?1001 R:R:E466 4.24 8 Yes Yes 0 5 0 1
R:R:G184 R:R:W182 5.63 0 No Yes 5 6 2 1
R:R:W182 R:R:W395 6.56 8 Yes Yes 6 5 1 1
R:R:E466 R:R:W182 3.27 8 Yes Yes 5 6 1 1
R:R:G268 R:R:H287 4.77 0 No Yes 7 7 2 1
R:R:H287 R:R:S270 5.58 8 Yes No 7 7 1 2
R:R:H287 R:R:P288 7.63 8 Yes No 7 6 1 2
R:R:H287 R:R:M429 2.63 8 Yes Yes 7 4 1 2
R:R:H287 R:R:L469 3.86 8 Yes Yes 7 6 1 2
R:R:M429 R:R:P288 6.71 8 Yes No 4 6 2 2
R:R:I393 R:R:W395 4.7 0 No Yes 5 5 2 1
R:R:W395 R:R:Y396 4.82 8 Yes No 5 5 1 2
R:R:E426 R:R:W395 2.18 0 No Yes 6 5 2 1
R:R:L469 R:R:M429 5.65 8 Yes Yes 6 4 2 2
R:R:E466 R:R:Q465 2.55 8 Yes No 5 4 1 2
R:R:E466 R:R:L469 2.65 8 Yes Yes 5 6 1 2
StatisticsValue
Average Number Of Links5.00
Average Number Of Links With An Hub4.00
Average Interaction Strength12.17
Average Nodes In Shell16.00
Average Hubs In Shell7.00
Average Links In Shell20.00
Average Links Mediated by Hubs In Shell20.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links6.50
Average Number Of Links With An Hub4.50
Average Interaction Strength9.21
Average Nodes In Shell19.50
Average Hubs In Shell7.50
Average Links In Shell26.00
Average Links Mediated by Hubs In Shell23.50

missing image


Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

missing image


Location of the nodes interacting with this ligand

(Click to enlarge 🔍)