Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 6LW5 | A | Peptide | Formylpeptide | FPR2-ALX | Homo sapiens | WKYMVm | - | - | 2.8 | 2020-03-25 | 10.1038/s41467-020-15009-1 |
A 2D representation of the interactions of QXV in 6LW5 colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:F74 | R:R:L109 | 15.83 | 0 | Yes | No | 7 | 8 | 2 | 1 | R:R:F292 | R:R:F74 | 11.79 | 0 | Yes | Yes | 7 | 7 | 2 | 2 | R:R:D106 | R:R:T157 | 4.34 | 1 | Yes | No | 5 | 7 | 1 | 2 | R:R:D106 | R:R:V160 | 4.38 | 1 | Yes | Yes | 5 | 4 | 1 | 2 | R:R:D106 | R:R:R201 | 5.96 | 1 | Yes | Yes | 5 | 5 | 1 | 1 | L:L:Y3 | R:R:D106 | 4.6 | 1 | Yes | Yes | 0 | 5 | 2 | 1 | L:L:?6 | R:R:D106 | 10.71 | 1 | Yes | Yes | 0 | 5 | 0 | 1 | R:R:L109 | R:R:W254 | 3.42 | 1 | No | Yes | 8 | 9 | 1 | 1 | L:L:?6 | R:R:L109 | 4.85 | 1 | Yes | No | 0 | 8 | 0 | 1 | R:R:F110 | R:R:F114 | 7.5 | 0 | Yes | No | 7 | 6 | 1 | 2 | R:R:F110 | R:R:L156 | 10.96 | 0 | Yes | No | 7 | 5 | 1 | 2 | L:L:?6 | R:R:F110 | 19.22 | 1 | Yes | Yes | 0 | 7 | 0 | 1 | R:R:F250 | R:R:V113 | 5.24 | 1 | Yes | No | 9 | 7 | 2 | 2 | R:R:V113 | R:R:W254 | 7.36 | 1 | No | Yes | 7 | 9 | 2 | 1 | R:R:R201 | R:R:V160 | 3.92 | 1 | Yes | Yes | 5 | 4 | 1 | 2 | L:L:Y3 | R:R:V160 | 3.79 | 1 | Yes | Yes | 0 | 4 | 2 | 2 | R:R:F178 | R:R:R201 | 7.48 | 1 | Yes | Yes | 4 | 5 | 2 | 1 | L:L:Y3 | R:R:F178 | 5.16 | 1 | Yes | Yes | 0 | 4 | 2 | 2 | R:R:R201 | R:R:R205 | 7.46 | 1 | Yes | Yes | 5 | 5 | 1 | 1 | L:L:Y3 | R:R:R201 | 8.23 | 1 | Yes | Yes | 0 | 5 | 2 | 1 | L:L:?6 | R:R:R201 | 8.52 | 1 | Yes | Yes | 0 | 5 | 0 | 1 | R:R:F257 | R:R:R205 | 4.28 | 0 | No | Yes | 7 | 5 | 2 | 1 | R:R:Q258 | R:R:R205 | 8.18 | 0 | No | Yes | 8 | 5 | 2 | 1 | R:R:A261 | R:R:R205 | 5.53 | 0 | No | Yes | 5 | 5 | 2 | 1 | L:L:M4 | R:R:R205 | 6.2 | 0 | No | Yes | 0 | 5 | 2 | 1 | L:L:?6 | R:R:R205 | 17.04 | 1 | Yes | Yes | 0 | 5 | 0 | 1 | R:R:F250 | R:R:W254 | 11.02 | 1 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:A291 | R:R:W254 | 7.78 | 0 | No | Yes | 8 | 9 | 2 | 1 | R:R:N294 | R:R:W254 | 3.39 | 0 | No | Yes | 9 | 9 | 2 | 1 | L:L:?6 | R:R:W254 | 3.99 | 1 | Yes | Yes | 0 | 9 | 0 | 1 | L:L:V5 | R:R:F292 | 3.93 | 0 | No | Yes | 0 | 7 | 1 | 2 | L:L:?6 | L:L:V5 | 6.53 | 1 | Yes | No | 0 | 0 | 0 | 1 | R:R:F110 | R:R:G209 | 3.01 | 0 | Yes | No | 7 | 6 | 1 | 2 | R:R:G202 | R:R:R205 | 3 | 0 | No | Yes | 4 | 5 | 2 | 1 | R:R:P159 | R:R:R201 | 1.44 | 0 | No | Yes | 8 | 5 | 2 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 7.00 | Average Number Of Links With An Hub | 5.00 | Average Interaction Strength | 10.12 | Average Nodes In Shell | 27.00 | Average Hubs In Shell | 12.00 | Average Links In Shell | 35.00 | Average Links Mediated by Hubs In Shell | 35.00 |
| Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 6OMM | A | Peptide | Formylpeptide | FPR2-ALX | Homo sapiens | WKYMVX | - | Gi1/Beta1/Gamma2 | 3.17 | 2020-02-26 | 10.1038/s41467-020-14728-9 |
A 2D representation of the interactions of QXV in 6OMM colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:F74 | R:R:L109 | 6.09 | 1 | Yes | Yes | 7 | 8 | 2 | 1 | R:R:F292 | R:R:F74 | 10.72 | 1 | Yes | Yes | 7 | 7 | 2 | 2 | R:R:D106 | R:R:V105 | 2.92 | 1 | Yes | No | 5 | 6 | 1 | 2 | R:R:L109 | R:R:V105 | 2.98 | 1 | Yes | No | 8 | 6 | 1 | 2 | R:R:D106 | R:R:V160 | 7.3 | 1 | Yes | No | 5 | 4 | 1 | 2 | L:L:V8 | R:R:D106 | 2.92 | 1 | No | Yes | 0 | 5 | 1 | 1 | L:L:?9 | R:R:D106 | 10.71 | 1 | Yes | Yes | 0 | 5 | 0 | 1 | R:R:L109 | R:R:W254 | 5.69 | 1 | Yes | Yes | 8 | 9 | 1 | 1 | R:R:F292 | R:R:L109 | 7.31 | 1 | Yes | Yes | 7 | 8 | 2 | 1 | L:L:?9 | R:R:L109 | 3.64 | 1 | Yes | Yes | 0 | 8 | 0 | 1 | R:R:F110 | R:R:F114 | 4.29 | 0 | Yes | No | 7 | 6 | 1 | 2 | R:R:F110 | R:R:L156 | 15.83 | 0 | Yes | No | 7 | 5 | 1 | 2 | L:L:?9 | R:R:F110 | 18.15 | 1 | Yes | Yes | 0 | 7 | 0 | 1 | R:R:F250 | R:R:V113 | 3.93 | 1 | Yes | No | 9 | 7 | 2 | 2 | R:R:V113 | R:R:W254 | 6.13 | 1 | No | Yes | 7 | 9 | 2 | 1 | R:R:R201 | R:R:V160 | 3.92 | 1 | Yes | No | 5 | 4 | 1 | 2 | R:R:F178 | R:R:R201 | 4.28 | 1 | Yes | Yes | 4 | 5 | 2 | 1 | L:L:Y6 | R:R:F178 | 5.16 | 1 | Yes | Yes | 0 | 4 | 2 | 2 | R:R:R201 | R:R:R205 | 6.4 | 1 | Yes | Yes | 5 | 5 | 1 | 1 | L:L:Y6 | R:R:R201 | 5.14 | 1 | Yes | Yes | 0 | 5 | 2 | 1 | L:L:?9 | R:R:R201 | 9.59 | 1 | Yes | Yes | 0 | 5 | 0 | 1 | R:R:Q258 | R:R:R205 | 7.01 | 1 | No | Yes | 8 | 5 | 2 | 1 | L:L:M7 | R:R:R205 | 7.44 | 0 | No | Yes | 0 | 5 | 2 | 1 | L:L:?9 | R:R:R205 | 23.43 | 1 | Yes | Yes | 0 | 5 | 0 | 1 | R:R:F250 | R:R:W254 | 7.02 | 1 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:F250 | R:R:N294 | 6.04 | 1 | Yes | Yes | 9 | 9 | 2 | 2 | R:R:A291 | R:R:W254 | 5.19 | 0 | No | Yes | 8 | 9 | 2 | 1 | R:R:N294 | R:R:W254 | 9.04 | 1 | Yes | Yes | 9 | 9 | 2 | 1 | L:L:?9 | R:R:W254 | 3 | 1 | Yes | Yes | 0 | 9 | 0 | 1 | L:L:?9 | L:L:V8 | 5.22 | 1 | Yes | No | 0 | 0 | 0 | 1 | R:R:P159 | R:R:R201 | 2.88 | 0 | No | Yes | 8 | 5 | 2 | 1 | R:R:A261 | R:R:R205 | 2.77 | 0 | No | Yes | 5 | 5 | 2 | 1 | R:R:G202 | R:R:R201 | 1.5 | 1 | No | Yes | 4 | 5 | 2 | 1 | R:R:G202 | R:R:R205 | 1.5 | 1 | No | Yes | 4 | 5 | 2 | 1 | R:R:A153 | R:R:F110 | 1.39 | 0 | No | Yes | 8 | 7 | 2 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 7.00 | Average Number Of Links With An Hub | 6.00 | Average Interaction Strength | 10.53 | Average Nodes In Shell | 26.00 | Average Hubs In Shell | 13.00 | Average Links In Shell | 35.00 | Average Links Mediated by Hubs In Shell | 35.00 |
| Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7T6U | A | Peptide | Formylpeptide | FPR2-ALX | Homo sapiens | CGEN-855A | - | Gi1/Beta1/Gamma2 | 2.9 | 2022-03-30 | 10.1038/s41467-022-28586-0 |
A 2D representation of the interactions of QXV in 7T6U colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | L:L:W19 | R:R:R205 | 4 | 0 | Yes | Yes | 0 | 5 | 2 | 1 | L:L:?21 | R:R:D106 | 16.66 | 5 | Yes | Yes | 0 | 5 | 0 | 1 | L:L:?21 | R:R:L109 | 6.07 | 5 | Yes | No | 0 | 8 | 0 | 1 | L:L:?21 | R:R:F110 | 14.95 | 5 | Yes | Yes | 0 | 7 | 0 | 1 | L:L:?21 | R:R:R201 | 14.91 | 5 | Yes | Yes | 0 | 5 | 0 | 1 | L:L:?21 | R:R:R205 | 14.91 | 5 | Yes | Yes | 0 | 5 | 0 | 1 | L:L:?21 | R:R:W254 | 5.99 | 5 | Yes | Yes | 0 | 9 | 0 | 1 | R:R:F74 | R:R:L109 | 9.74 | 5 | Yes | No | 7 | 8 | 2 | 1 | R:R:F292 | R:R:F74 | 12.86 | 5 | Yes | Yes | 7 | 7 | 2 | 2 | R:R:D106 | R:R:V160 | 4.38 | 5 | Yes | No | 5 | 4 | 1 | 2 | R:R:D106 | R:R:R201 | 5.96 | 5 | Yes | Yes | 5 | 5 | 1 | 1 | R:R:F292 | R:R:L109 | 7.31 | 5 | Yes | No | 7 | 8 | 2 | 1 | R:R:F110 | R:R:F114 | 7.5 | 0 | Yes | No | 7 | 6 | 1 | 2 | R:R:F110 | R:R:L156 | 7.31 | 0 | Yes | Yes | 7 | 5 | 1 | 2 | R:R:F250 | R:R:V113 | 3.93 | 5 | Yes | No | 9 | 7 | 2 | 2 | R:R:V113 | R:R:W254 | 4.9 | 5 | No | Yes | 7 | 9 | 2 | 1 | R:R:R201 | R:R:V160 | 3.92 | 5 | Yes | No | 5 | 4 | 1 | 2 | R:R:F178 | R:R:R201 | 4.28 | 0 | Yes | Yes | 4 | 5 | 2 | 1 | R:R:G202 | R:R:R205 | 6 | 0 | No | Yes | 4 | 5 | 2 | 1 | R:R:Q258 | R:R:R205 | 8.18 | 31 | Yes | Yes | 8 | 5 | 2 | 1 | R:R:A261 | R:R:R205 | 5.53 | 0 | No | Yes | 5 | 5 | 2 | 1 | R:R:F250 | R:R:W254 | 6.01 | 5 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:A291 | R:R:W254 | 5.19 | 0 | No | Yes | 8 | 9 | 2 | 1 | R:R:N294 | R:R:W254 | 6.78 | 0 | No | Yes | 9 | 9 | 2 | 1 | R:R:F110 | R:R:G209 | 3.01 | 0 | Yes | No | 7 | 6 | 1 | 2 | R:R:D106 | R:R:T157 | 2.89 | 5 | Yes | No | 5 | 7 | 1 | 2 | |
Statistics | Value |
---|
Average Number Of Links | 6.00 | Average Number Of Links With An Hub | 5.00 | Average Interaction Strength | 12.25 | Average Nodes In Shell | 23.00 | Average Hubs In Shell | 13.00 | Average Links In Shell | 26.00 | Average Links Mediated by Hubs In Shell | 26.00 |
| Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|