CodeQXV
NameD-methioninamide
Synonyms
Identifier(2~{R})-2-azanyl-4-methylsulfanyl-butanamide
FormulaC5 H12 N2 O S
Molecular Weight148.227
SMILESCSCC[C@H](C(=O)N)N
PubChem11571827
Formal Charge0
Total Atoms21
Total Chiral Atoms1
Total Bonds20
Total Aromatic Bonds0
Networks3
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This ligand is also present in the following 3 networks:

Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
6LW5 A Peptide Formylpeptide FPR2-ALX Homo sapiens WKYMVm - - 2.8 2020-03-25 10.1038/s41467-020-15009-1

A 2D representation of the interactions of QXV in 6LW5
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:F74 R:R:L109 15.83 0 Yes No 7 8 2 1
R:R:F292 R:R:F74 11.79 0 Yes Yes 7 7 2 2
R:R:D106 R:R:T157 4.34 1 Yes No 5 7 1 2
R:R:D106 R:R:V160 4.38 1 Yes Yes 5 4 1 2
R:R:D106 R:R:R201 5.96 1 Yes Yes 5 5 1 1
L:L:Y3 R:R:D106 4.6 1 Yes Yes 0 5 2 1
L:L:?6 R:R:D106 10.71 1 Yes Yes 0 5 0 1
R:R:L109 R:R:W254 3.42 1 No Yes 8 9 1 1
L:L:?6 R:R:L109 4.85 1 Yes No 0 8 0 1
R:R:F110 R:R:F114 7.5 0 Yes No 7 6 1 2
R:R:F110 R:R:L156 10.96 0 Yes No 7 5 1 2
L:L:?6 R:R:F110 19.22 1 Yes Yes 0 7 0 1
R:R:F250 R:R:V113 5.24 1 Yes No 9 7 2 2
R:R:V113 R:R:W254 7.36 1 No Yes 7 9 2 1
R:R:R201 R:R:V160 3.92 1 Yes Yes 5 4 1 2
L:L:Y3 R:R:V160 3.79 1 Yes Yes 0 4 2 2
R:R:F178 R:R:R201 7.48 1 Yes Yes 4 5 2 1
L:L:Y3 R:R:F178 5.16 1 Yes Yes 0 4 2 2
R:R:R201 R:R:R205 7.46 1 Yes Yes 5 5 1 1
L:L:Y3 R:R:R201 8.23 1 Yes Yes 0 5 2 1
L:L:?6 R:R:R201 8.52 1 Yes Yes 0 5 0 1
R:R:F257 R:R:R205 4.28 0 No Yes 7 5 2 1
R:R:Q258 R:R:R205 8.18 0 No Yes 8 5 2 1
R:R:A261 R:R:R205 5.53 0 No Yes 5 5 2 1
L:L:M4 R:R:R205 6.2 0 No Yes 0 5 2 1
L:L:?6 R:R:R205 17.04 1 Yes Yes 0 5 0 1
R:R:F250 R:R:W254 11.02 1 Yes Yes 9 9 2 1
R:R:A291 R:R:W254 7.78 0 No Yes 8 9 2 1
R:R:N294 R:R:W254 3.39 0 No Yes 9 9 2 1
L:L:?6 R:R:W254 3.99 1 Yes Yes 0 9 0 1
L:L:V5 R:R:F292 3.93 0 No Yes 0 7 1 2
L:L:?6 L:L:V5 6.53 1 Yes No 0 0 0 1
R:R:F110 R:R:G209 3.01 0 Yes No 7 6 1 2
R:R:G202 R:R:R205 3 0 No Yes 4 5 2 1
R:R:P159 R:R:R201 1.44 0 No Yes 8 5 2 1
StatisticsValue
Average Number Of Links7.00
Average Number Of Links With An Hub5.00
Average Interaction Strength10.12
Average Nodes In Shell27.00
Average Hubs In Shell12.00
Average Links In Shell35.00
Average Links Mediated by Hubs In Shell35.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
6OMM A Peptide Formylpeptide FPR2-ALX Homo sapiens WKYMVX - Gi1/Beta1/Gamma2 3.17 2020-02-26 10.1038/s41467-020-14728-9

A 2D representation of the interactions of QXV in 6OMM
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:F74 R:R:L109 6.09 1 Yes Yes 7 8 2 1
R:R:F292 R:R:F74 10.72 1 Yes Yes 7 7 2 2
R:R:D106 R:R:V105 2.92 1 Yes No 5 6 1 2
R:R:L109 R:R:V105 2.98 1 Yes No 8 6 1 2
R:R:D106 R:R:V160 7.3 1 Yes No 5 4 1 2
L:L:V8 R:R:D106 2.92 1 No Yes 0 5 1 1
L:L:?9 R:R:D106 10.71 1 Yes Yes 0 5 0 1
R:R:L109 R:R:W254 5.69 1 Yes Yes 8 9 1 1
R:R:F292 R:R:L109 7.31 1 Yes Yes 7 8 2 1
L:L:?9 R:R:L109 3.64 1 Yes Yes 0 8 0 1
R:R:F110 R:R:F114 4.29 0 Yes No 7 6 1 2
R:R:F110 R:R:L156 15.83 0 Yes No 7 5 1 2
L:L:?9 R:R:F110 18.15 1 Yes Yes 0 7 0 1
R:R:F250 R:R:V113 3.93 1 Yes No 9 7 2 2
R:R:V113 R:R:W254 6.13 1 No Yes 7 9 2 1
R:R:R201 R:R:V160 3.92 1 Yes No 5 4 1 2
R:R:F178 R:R:R201 4.28 1 Yes Yes 4 5 2 1
L:L:Y6 R:R:F178 5.16 1 Yes Yes 0 4 2 2
R:R:R201 R:R:R205 6.4 1 Yes Yes 5 5 1 1
L:L:Y6 R:R:R201 5.14 1 Yes Yes 0 5 2 1
L:L:?9 R:R:R201 9.59 1 Yes Yes 0 5 0 1
R:R:Q258 R:R:R205 7.01 1 No Yes 8 5 2 1
L:L:M7 R:R:R205 7.44 0 No Yes 0 5 2 1
L:L:?9 R:R:R205 23.43 1 Yes Yes 0 5 0 1
R:R:F250 R:R:W254 7.02 1 Yes Yes 9 9 2 1
R:R:F250 R:R:N294 6.04 1 Yes Yes 9 9 2 2
R:R:A291 R:R:W254 5.19 0 No Yes 8 9 2 1
R:R:N294 R:R:W254 9.04 1 Yes Yes 9 9 2 1
L:L:?9 R:R:W254 3 1 Yes Yes 0 9 0 1
L:L:?9 L:L:V8 5.22 1 Yes No 0 0 0 1
R:R:P159 R:R:R201 2.88 0 No Yes 8 5 2 1
R:R:A261 R:R:R205 2.77 0 No Yes 5 5 2 1
R:R:G202 R:R:R201 1.5 1 No Yes 4 5 2 1
R:R:G202 R:R:R205 1.5 1 No Yes 4 5 2 1
R:R:A153 R:R:F110 1.39 0 No Yes 8 7 2 1
StatisticsValue
Average Number Of Links7.00
Average Number Of Links With An Hub6.00
Average Interaction Strength10.53
Average Nodes In Shell26.00
Average Hubs In Shell13.00
Average Links In Shell35.00
Average Links Mediated by Hubs In Shell35.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7T6U A Peptide Formylpeptide FPR2-ALX Homo sapiens CGEN-855A - Gi1/Beta1/Gamma2 2.9 2022-03-30 10.1038/s41467-022-28586-0

A 2D representation of the interactions of QXV in 7T6U
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:W19 R:R:R205 4 0 Yes Yes 0 5 2 1
L:L:?21 R:R:D106 16.66 5 Yes Yes 0 5 0 1
L:L:?21 R:R:L109 6.07 5 Yes No 0 8 0 1
L:L:?21 R:R:F110 14.95 5 Yes Yes 0 7 0 1
L:L:?21 R:R:R201 14.91 5 Yes Yes 0 5 0 1
L:L:?21 R:R:R205 14.91 5 Yes Yes 0 5 0 1
L:L:?21 R:R:W254 5.99 5 Yes Yes 0 9 0 1
R:R:F74 R:R:L109 9.74 5 Yes No 7 8 2 1
R:R:F292 R:R:F74 12.86 5 Yes Yes 7 7 2 2
R:R:D106 R:R:V160 4.38 5 Yes No 5 4 1 2
R:R:D106 R:R:R201 5.96 5 Yes Yes 5 5 1 1
R:R:F292 R:R:L109 7.31 5 Yes No 7 8 2 1
R:R:F110 R:R:F114 7.5 0 Yes No 7 6 1 2
R:R:F110 R:R:L156 7.31 0 Yes Yes 7 5 1 2
R:R:F250 R:R:V113 3.93 5 Yes No 9 7 2 2
R:R:V113 R:R:W254 4.9 5 No Yes 7 9 2 1
R:R:R201 R:R:V160 3.92 5 Yes No 5 4 1 2
R:R:F178 R:R:R201 4.28 0 Yes Yes 4 5 2 1
R:R:G202 R:R:R205 6 0 No Yes 4 5 2 1
R:R:Q258 R:R:R205 8.18 31 Yes Yes 8 5 2 1
R:R:A261 R:R:R205 5.53 0 No Yes 5 5 2 1
R:R:F250 R:R:W254 6.01 5 Yes Yes 9 9 2 1
R:R:A291 R:R:W254 5.19 0 No Yes 8 9 2 1
R:R:N294 R:R:W254 6.78 0 No Yes 9 9 2 1
R:R:F110 R:R:G209 3.01 0 Yes No 7 6 1 2
R:R:D106 R:R:T157 2.89 5 Yes No 5 7 1 2
StatisticsValue
Average Number Of Links6.00
Average Number Of Links With An Hub5.00
Average Interaction Strength12.25
Average Nodes In Shell23.00
Average Hubs In Shell13.00
Average Links In Shell26.00
Average Links Mediated by Hubs In Shell26.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links6.67
Average Number Of Links With An Hub5.33
Average Interaction Strength10.97
Average Nodes In Shell25.33
Average Hubs In Shell12.67
Average Links In Shell32.00
Average Links Mediated by Hubs In Shell32.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

missing image


Location of the nodes interacting with this ligand

(Click to enlarge 🔍)