CodeRGI
NameMETHYLCARBAMIC ACID
Synonyms
Identifiermethylcarbamic acid
FormulaC2 H5 N O2
Molecular Weight75.067
SMILESCNC(=O)O
PubChem30536
Formal Charge0
Total Atoms10
Total Chiral Atoms0
Total Bonds9
Total Aromatic Bonds0
Networks1
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This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7X1T A Peptide Thyrotropin-releasing hormone TRH Homo sapiens Taltirelin - chim(NtGi2L-Gs-CtGq)/Beta1/Gamma2 3.26 2022-08-31 10.1038/s41422-022-00646-6

A 2D representation of the interactions of RGI in 7X1T
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:R185 R:R:Y181 13.38 1 Yes Yes 2 4 1 1
R:R:Y181 R:R:Y188 3.97 1 Yes Yes 4 5 1 2
R:R:Y181 R:R:Y192 6.95 1 Yes Yes 4 5 1 2
L:L:?1 R:R:Y181 6.3 1 Yes Yes 0 4 0 1
L:L:D2 R:R:Y181 10.34 1 Yes Yes 0 4 1 1
L:L:H3 R:R:Y181 7.62 1 Yes Yes 0 4 2 1
R:R:R185 R:R:Y192 8.23 1 Yes Yes 2 5 1 2
R:R:R185 R:R:V286 2.62 1 Yes Yes 2 6 1 2
R:R:N289 R:R:R185 8.44 1 Yes Yes 4 2 1 1
R:R:P295 R:R:R185 2.88 1 No Yes 1 2 2 1
L:L:?1 R:R:R185 6.53 1 Yes Yes 0 2 0 1
L:L:D2 R:R:R185 5.96 1 Yes Yes 0 2 1 1
R:R:Y188 R:R:Y192 37.73 1 Yes Yes 5 5 2 2
R:R:V286 R:R:Y192 10.09 1 Yes Yes 6 5 2 2
R:R:L285 R:R:N289 2.75 1 Yes Yes 4 4 2 1
L:L:D2 R:R:V286 7.3 1 Yes Yes 0 6 1 2
R:R:N289 R:R:P295 4.89 1 Yes No 4 1 1 2
L:L:?1 R:R:N289 5.54 1 Yes Yes 0 4 0 1
R:R:L302 R:R:Q297 3.99 1 No No 4 3 1 1
L:L:?1 R:R:Q297 8.94 1 Yes No 0 3 0 1
L:L:?1 R:R:L302 5.58 1 Yes No 0 4 0 1
L:L:?1 L:L:D2 27.36 1 Yes Yes 0 0 0 1
R:R:R185 R:R:S290 1.32 1 Yes Yes 2 4 1 2
StatisticsValue
Average Number Of Links6.00
Average Number Of Links With An Hub4.00
Average Interaction Strength10.04
Average Nodes In Shell14.00
Average Hubs In Shell11.00
Average Links In Shell23.00
Average Links Mediated by Hubs In Shell22.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links6.00
Average Number Of Links With An Hub4.00
Average Interaction Strength10.04
Average Nodes In Shell14.00
Average Hubs In Shell11.00
Average Links In Shell23.00
Average Links Mediated by Hubs In Shell22.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)