CodeSRO
NameSerotonin
Synonymssérotonine
Identifier3-(2-aminoethyl)-1H-indol-5-ol
FormulaC10 H12 N2 O
Molecular Weight176.215
SMILESc1cc2c(cc1O)c(c[nH]2)CCN
PubChem5202
Formal Charge0
Total Atoms25
Total Chiral Atoms0
Total Bonds26
Total Aromatic Bonds10
Networks8
 missing image

This ligand is also present in the following 8 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7E2Y A Amine 5-Hydroxytryptamine 5-HT1A Homo sapiens Serotonin - Gi1/Beta1/Gamma2 3 2021-04-14 10.1038/s41586-021-03376-8

A 2D representation of the interactions of SRO in 7E2Y
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:D116 R:R:V89 10.22 2 Yes No 8 8 1 2
R:R:L90 R:R:Y390 5.86 0 Yes Yes 8 8 2 1
R:R:A93 R:R:Y390 4 0 No Yes 7 8 2 1
R:R:C120 R:R:D116 4.67 2 No Yes 7 8 1 1
R:R:D116 R:R:Y390 10.34 2 Yes Yes 8 8 1 1
L:L:?1 R:R:D116 7.87 2 Yes Yes 0 8 0 1
L:L:?1 R:R:C120 10.52 2 Yes No 0 7 0 1
R:R:I167 R:R:T121 6.08 0 Yes Yes 8 8 2 2
R:R:A203 R:R:T121 3.36 2 No Yes 8 8 1 2
R:R:I167 R:R:S199 3.1 0 Yes No 8 8 2 1
R:R:S199 R:R:Y195 2.54 0 No Yes 8 8 1 2
L:L:?1 R:R:S199 7.46 2 Yes No 0 8 0 1
R:R:F362 R:R:T200 2.59 2 Yes No 7 7 1 2
R:R:A203 R:R:F362 2.77 2 No Yes 8 7 1 1
L:L:?1 R:R:A203 2.61 2 Yes No 0 8 0 1
R:R:F204 R:R:W358 4.01 2 Yes Yes 8 8 2 2
R:R:F204 R:R:F362 20.36 2 Yes Yes 8 7 2 1
R:R:F362 R:R:W358 3.01 2 Yes Yes 7 8 1 2
R:R:F361 R:R:F362 3.22 2 No Yes 8 7 1 1
R:R:F361 R:R:N386 7.25 2 No No 8 7 1 2
L:L:?1 R:R:F361 10.09 2 Yes No 0 8 0 1
L:L:?1 R:R:F362 8.07 2 Yes Yes 0 7 0 1
R:R:N386 R:R:Y390 5.81 0 No Yes 7 8 2 1
R:R:W387 R:R:Y390 9.65 2 Yes Yes 8 8 2 1
L:L:?1 R:R:Y390 3.89 2 Yes Yes 0 8 0 1
L:L:?1 R:R:A365 1.31 2 Yes No 0 8 0 1
StatisticsValue
Average Number Of Links8.00
Average Number Of Links With An Hub3.00
Average Interaction Strength6.48
Average Nodes In Shell20.00
Average Hubs In Shell11.00
Average Links In Shell26.00
Average Links Mediated by Hubs In Shell25.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7E32 A Amine 5-Hydroxytryptamine 5-HT1D Homo sapiens Serotonin - Gi1/Beta1/Gamma2 2.9 2021-04-21 10.1038/s41586-021-03376-8

A 2D representation of the interactions of SRO in 7E32
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:D118 R:R:V91 5.84 1 No Yes 8 8 1 2
R:R:V91 R:R:Y346 5.05 1 Yes Yes 8 8 2 1
R:R:S95 R:R:W343 6.18 1 No Yes 7 7 2 2
R:R:S95 R:R:Y346 6.36 1 No Yes 7 8 2 1
R:R:D118 R:R:Y346 9.2 1 No Yes 8 8 1 1
L:L:?1 R:R:D118 11.24 1 Yes No 0 8 0 1
R:R:I119 R:R:S170 6.19 0 No No 7 8 1 2
L:L:?1 R:R:I119 7.1 1 Yes No 0 7 0 1
R:R:C122 R:R:W314 6.53 1 No Yes 7 8 1 1
L:L:?1 R:R:C122 13.15 1 Yes No 0 7 0 1
R:R:F310 R:R:I126 5.02 1 Yes Yes 9 8 2 2
R:R:I126 R:R:W314 5.87 1 Yes Yes 8 8 2 1
L:L:?1 R:R:V190 4.94 1 Yes No 0 6 0 1
R:R:S201 R:R:Y197 10.17 0 No No 7 8 1 2
L:L:?1 R:R:S201 7.46 1 Yes No 0 7 0 1
L:L:?1 R:R:A205 3.92 1 Yes No 0 7 0 1
R:R:F206 R:R:F310 10.72 1 Yes Yes 8 9 2 2
R:R:F206 R:R:F318 20.36 1 Yes Yes 8 7 2 1
R:R:F310 R:R:W314 7.02 1 Yes Yes 9 8 2 1
R:R:F317 R:R:W314 11.02 1 Yes Yes 8 8 1 1
R:R:F318 R:R:W314 10.02 1 Yes Yes 7 8 1 1
R:R:G345 R:R:W314 8.44 0 No Yes 7 8 2 1
R:R:N348 R:R:W314 12.43 0 No Yes 9 8 2 1
L:L:?1 R:R:W314 3.77 1 Yes Yes 0 8 0 1
R:R:F317 R:R:F318 3.22 1 Yes Yes 8 7 1 1
R:R:F317 R:R:F338 3.22 1 Yes No 8 5 1 2
L:L:?1 R:R:F317 11.1 1 Yes Yes 0 8 0 1
L:L:?1 R:R:F318 9.08 1 Yes Yes 0 7 0 1
L:L:?1 R:R:S321 4.98 1 Yes No 0 7 0 1
R:R:T342 R:R:Y346 3.75 0 No Yes 6 8 2 1
R:R:W343 R:R:Y346 6.75 1 Yes Yes 7 8 2 1
L:L:?1 R:R:Y346 4.86 1 Yes Yes 0 8 0 1
StatisticsValue
Average Number Of Links11.00
Average Number Of Links With An Hub4.00
Average Interaction Strength7.42
Average Nodes In Shell24.00
Average Hubs In Shell10.00
Average Links In Shell32.00
Average Links Mediated by Hubs In Shell30.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7WC4 A Amine 5-Hydroxytryptamine 5-HT2A Homo sapiens Serotonin - - 3.2 2022-01-26 10.1126/science.abl8615

A 2D representation of the interactions of SRO in 7WC4
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:V127 R:R:W151 3.68 1 Yes Yes 8 5 2 1
R:R:D155 R:R:V127 7.3 1 No Yes 8 8 1 2
R:R:V127 R:R:Y370 3.79 1 Yes Yes 8 7 2 2
R:R:V130 R:R:W151 13.48 0 No Yes 4 5 2 1
R:R:W141 R:R:W151 6.56 1 Yes Yes 7 5 2 1
R:R:C227 R:R:W141 14.37 1 Yes Yes 9 7 2 2
R:R:C227 R:R:W151 3.92 1 Yes Yes 9 5 2 1
L:L:?1 R:R:W151 6.61 0 Yes Yes 0 5 0 1
R:R:D155 R:R:Y370 10.34 1 No Yes 8 7 1 2
L:L:?1 R:R:D155 12.37 0 Yes No 0 8 0 1
R:R:I210 R:R:V156 4.61 0 No No 6 6 2 1
L:L:?1 R:R:V156 3.7 0 Yes No 0 6 0 1
R:R:K223 R:R:L228 7.05 0 No No 3 4 2 1
L:L:?1 R:R:L228 6.88 0 Yes No 0 4 0 1
R:R:F339 R:R:W336 7.02 1 Yes Yes 7 8 1 2
R:R:W336 R:R:Y370 3.86 0 Yes Yes 8 7 2 2
R:R:F339 R:R:N343 4.83 1 Yes No 7 7 1 2
R:R:F339 R:R:L362 7.31 1 Yes No 7 3 1 2
R:R:F339 R:R:V366 5.24 1 Yes No 7 6 1 2
L:L:?1 R:R:F339 6.05 0 Yes Yes 0 7 0 1
R:R:L362 R:R:N343 6.87 1 No No 3 7 2 2
R:R:V366 R:R:Y370 6.31 1 No Yes 6 7 2 2
StatisticsValue
Average Number Of Links5.00
Average Number Of Links With An Hub2.00
Average Interaction Strength7.12
Average Nodes In Shell17.00
Average Hubs In Shell8.00
Average Links In Shell22.00
Average Links Mediated by Hubs In Shell19.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7XT8 A Amine 5-Hydroxytryptamine 5-HT4 Homo sapiens Serotonin - Gs/Beta1/Gamma2 3.1 2022-07-27 10.1016/j.molcel.2022.05.031

A 2D representation of the interactions of SRO in 7XT8
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:D100 R:R:V73 7.3 3 Yes No 7 7 1 2
R:R:V73 R:R:Y302 3.79 3 No Yes 7 7 2 2
R:R:F186 R:R:T97 9.08 3 Yes No 4 4 1 2
R:R:D100 R:R:T104 4.34 3 Yes No 7 7 1 1
R:R:D100 R:R:Y302 10.34 3 Yes Yes 7 7 1 2
L:L:?1 R:R:D100 9 3 Yes Yes 0 7 0 1
L:L:?1 R:R:V101 13.58 3 Yes No 0 5 0 1
R:R:T104 R:R:W272 10.92 3 No Yes 7 8 1 2
L:L:?1 R:R:T104 17.1 3 Yes No 0 7 0 1
R:R:A200 R:R:T105 5.03 0 No Yes 5 6 1 2
R:R:F186 R:R:N162 3.62 3 Yes Yes 4 5 1 2
R:R:N162 R:R:Y192 8.14 3 Yes Yes 5 7 2 2
R:R:F186 R:R:V188 5.24 3 Yes Yes 4 4 1 1
R:R:F186 R:R:Y192 5.16 3 Yes Yes 4 7 1 2
L:L:?1 R:R:F186 6.05 3 Yes Yes 0 4 0 1
R:R:V188 R:R:Y192 5.05 3 Yes Yes 4 7 1 2
R:R:A193 R:R:V188 3.39 0 No Yes 5 4 2 1
R:R:N279 R:R:V188 5.91 3 Yes Yes 5 4 1 1
L:L:?1 R:R:V188 3.7 3 Yes Yes 0 4 0 1
R:R:F276 R:R:S197 5.28 0 Yes No 7 6 1 2
R:R:N279 R:R:S197 5.96 3 Yes No 5 6 1 2
L:L:?1 R:R:A200 3.92 3 Yes No 0 5 0 1
R:R:F201 R:R:F276 19.29 18 Yes Yes 8 7 2 1
R:R:F276 R:R:W272 5.01 0 Yes Yes 7 8 1 2
R:R:F275 R:R:W294 9.02 0 No Yes 6 4 1 2
R:R:F275 R:R:L298 7.31 0 No No 6 5 1 2
L:L:?1 R:R:F275 6.05 3 Yes No 0 6 0 1
L:L:?1 R:R:F276 8.07 3 Yes Yes 0 7 0 1
R:R:N279 R:R:W294 5.65 3 Yes Yes 5 4 1 2
L:L:?1 R:R:N279 10.24 3 Yes Yes 0 5 0 1
R:R:L298 R:R:Y302 14.07 0 No Yes 5 7 2 2
StatisticsValue
Average Number Of Links9.00
Average Number Of Links With An Hub5.00
Average Interaction Strength8.63
Average Nodes In Shell22.00
Average Hubs In Shell13.00
Average Links In Shell31.00
Average Links Mediated by Hubs In Shell30.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7XT9 A Amine 5-Hydroxytryptamine 5-HT4 Homo sapiens Serotonin - Gs/Beta1/Gamma2 3.2 2022-07-27 10.1016/j.molcel.2022.05.031

A 2D representation of the interactions of SRO in 7XT9
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:D100 R:R:V73 8.76 1 Yes No 7 7 1 2
R:R:V73 R:R:Y302 5.05 1 No Yes 7 7 2 2
R:R:D100 R:R:R96 9.53 1 Yes No 7 5 1 2
R:R:F186 R:R:T97 10.38 1 Yes No 4 4 1 2
R:R:D100 R:R:T104 4.34 1 Yes No 7 7 1 1
R:R:D100 R:R:Y302 10.34 1 Yes Yes 7 7 1 2
L:L:?1 R:R:D100 6.75 1 Yes Yes 0 7 0 1
L:L:?1 R:R:V101 14.81 1 Yes No 0 5 0 1
R:R:T104 R:R:W272 8.49 1 No Yes 7 8 1 2
L:L:?1 R:R:T104 14.66 1 Yes No 0 7 0 1
R:R:F186 R:R:N162 3.62 1 Yes Yes 4 5 1 2
R:R:N162 R:R:Y192 8.14 0 Yes Yes 5 7 2 2
R:R:F186 R:R:V188 5.24 1 Yes Yes 4 4 1 1
L:L:?1 R:R:F186 6.05 1 Yes Yes 0 4 0 1
R:R:V188 R:R:Y192 6.31 1 Yes Yes 4 7 1 2
R:R:A193 R:R:V188 3.39 0 No Yes 5 4 2 1
R:R:N279 R:R:V188 5.91 1 Yes Yes 5 4 1 1
L:L:?1 R:R:V188 3.7 1 Yes Yes 0 4 0 1
R:R:F276 R:R:S197 3.96 0 Yes No 7 6 1 2
R:R:N279 R:R:S197 5.96 1 Yes No 5 6 1 2
R:R:F201 R:R:F276 20.36 0 Yes Yes 8 7 2 1
R:R:F276 R:R:W272 6.01 0 Yes Yes 7 8 1 2
R:R:F275 R:R:W294 11.02 0 No Yes 6 4 1 2
R:R:F275 R:R:L298 6.09 0 No No 6 5 1 2
L:L:?1 R:R:F275 8.07 1 Yes No 0 6 0 1
L:L:?1 R:R:F276 7.06 1 Yes Yes 0 7 0 1
R:R:N279 R:R:W294 4.52 1 Yes Yes 5 4 1 2
L:L:?1 R:R:N279 9.1 1 Yes Yes 0 5 0 1
R:R:L298 R:R:Y302 12.89 0 No Yes 5 7 2 2
R:R:S153 R:R:V101 3.23 10 No No 7 5 2 1
StatisticsValue
Average Number Of Links8.00
Average Number Of Links With An Hub5.00
Average Interaction Strength8.78
Average Nodes In Shell22.00
Average Hubs In Shell12.00
Average Links In Shell30.00
Average Links Mediated by Hubs In Shell28.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7XTA A Amine 5-Hydroxytryptamine 5-HT4 Homo sapiens Serotonin - Gi1/Beta1/Gamma2 3.2 2022-07-27 10.1016/j.molcel.2022.05.031

A 2D representation of the interactions of SRO in 7XTA
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:D100 R:R:V73 7.3 1 Yes Yes 7 7 1 2
R:R:V73 R:R:Y302 5.05 1 Yes Yes 7 7 2 2
R:R:D100 R:R:T104 4.34 1 Yes No 7 7 1 1
R:R:D100 R:R:Y302 11.49 1 Yes Yes 7 7 1 2
L:L:?1 R:R:D100 6.75 1 Yes Yes 0 7 0 1
R:R:S153 R:R:V101 3.23 16 No No 7 5 2 1
R:R:I157 R:R:V101 4.61 1 Yes No 5 5 2 1
L:L:?1 R:R:V101 12.34 1 Yes No 0 5 0 1
R:R:T104 R:R:W272 7.28 1 No Yes 7 8 1 2
L:L:?1 R:R:T104 8.55 1 Yes No 0 7 0 1
R:R:C196 R:R:I152 4.91 0 No No 5 5 1 2
R:R:F186 R:R:I157 5.02 1 Yes Yes 4 5 2 2
R:R:I157 R:R:Y192 6.04 1 Yes Yes 5 7 2 2
R:R:F186 R:R:V188 3.93 1 Yes Yes 4 4 2 1
R:R:F186 R:R:Y192 3.09 1 Yes Yes 4 7 2 2
R:R:V188 R:R:Y192 5.05 1 Yes Yes 4 7 1 2
R:R:A193 R:R:V188 3.39 0 No Yes 5 4 2 1
R:R:N279 R:R:V188 4.43 1 Yes Yes 5 4 1 1
L:L:?1 R:R:V188 3.7 1 Yes Yes 0 4 0 1
R:R:C196 R:R:Y192 9.41 0 No Yes 5 7 1 2
L:L:?1 R:R:C196 6.57 1 Yes No 0 5 0 1
R:R:N279 R:R:S197 5.96 1 Yes No 5 6 1 2
R:R:A200 R:R:F276 2.77 0 No Yes 5 7 2 1
R:R:F201 R:R:F276 21.43 1 Yes Yes 8 7 2 1
R:R:F276 R:R:W272 4.01 0 Yes Yes 7 8 1 2
R:R:F275 R:R:W294 5.01 0 No Yes 6 4 1 2
R:R:F275 R:R:L298 4.87 0 No No 6 5 1 2
L:L:?1 R:R:F275 13.12 1 Yes No 0 6 0 1
L:L:?1 R:R:F276 9.08 1 Yes Yes 0 7 0 1
R:R:N279 R:R:W294 4.52 1 Yes Yes 5 4 1 2
L:L:?1 R:R:N279 12.51 1 Yes Yes 0 5 0 1
R:R:L298 R:R:Y302 15.24 0 No Yes 5 7 2 2
StatisticsValue
Average Number Of Links8.00
Average Number Of Links With An Hub4.00
Average Interaction Strength9.08
Average Nodes In Shell23.00
Average Hubs In Shell13.00
Average Links In Shell32.00
Average Links Mediated by Hubs In Shell29.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7XTB A Amine 5-Hydroxytryptamine 5-HT6 Homo sapiens Serotonin - Gs/Beta1/Gamma2 3.3 2022-07-27 10.1016/j.molcel.2022.05.031

A 2D representation of the interactions of SRO in 7XTB
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:D106 R:R:V79 7.3 26 No Yes 7 7 1 2
R:R:V79 R:R:Y310 3.79 26 Yes Yes 7 7 2 2
R:R:D106 R:R:Y310 9.2 26 No Yes 7 7 1 2
L:L:?1 R:R:D106 6.75 0 Yes No 0 7 0 1
R:R:S158 R:R:V107 6.46 0 No No 7 6 2 1
L:L:?1 R:R:V107 13.58 0 Yes No 0 6 0 1
R:R:C110 R:R:W281 5.22 0 No Yes 6 8 1 2
L:L:?1 R:R:C110 11.83 0 Yes No 0 6 0 1
R:R:S111 R:R:T196 7.99 0 No No 7 6 2 1
R:R:A192 R:R:F188 4.16 0 No No 6 7 1 2
R:R:N288 R:R:V189 4.43 0 No No 6 5 1 2
L:L:?1 R:R:T196 4.89 0 Yes No 0 6 0 1
R:R:F197 R:R:W281 3.01 10 Yes Yes 8 8 2 2
R:R:F197 R:R:F285 27.86 10 Yes No 8 6 2 1
R:R:F285 R:R:W281 6.01 10 No Yes 6 8 1 2
R:R:F284 R:R:F302 4.29 0 No No 7 4 1 2
R:R:F284 R:R:T306 7.78 0 No No 7 4 1 2
L:L:?1 R:R:F284 6.05 0 Yes No 0 7 0 1
L:L:?1 R:R:F285 5.05 0 Yes No 0 6 0 1
L:L:?1 R:R:N288 6.83 0 Yes No 0 6 0 1
R:R:T306 R:R:Y310 6.24 0 No Yes 4 7 2 2
L:L:?1 R:R:A192 2.61 0 Yes No 0 6 0 1
R:R:L195 R:R:T196 1.47 0 No No 3 6 2 1
StatisticsValue
Average Number Of Links8.00
Average Number Of Links With An Hub0.00
Average Interaction Strength7.20
Average Nodes In Shell20.00
Average Hubs In Shell5.00
Average Links In Shell23.00
Average Links Mediated by Hubs In Shell16.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7YS6 A Amine 5-Hydroxytryptamine 5-HT6 Homo sapiens Serotonin - chim(NtGi1-Gs)/Beta1/Gamma2 3 2023-03-29  10.1073/pnas.2209917120

A 2D representation of the interactions of SRO in 7YS6
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:D106 R:R:V79 4.38 5 No Yes 7 7 1 2
R:R:V79 R:R:Y310 3.79 5 Yes Yes 7 7 2 2
R:R:L162 R:R:T103 4.42 0 Yes No 5 4 2 2
R:R:L182 R:R:T103 8.84 0 No No 4 4 1 2
R:R:D106 R:R:Y310 11.49 5 No Yes 7 7 1 2
L:L:?1 R:R:D106 7.87 0 Yes No 0 7 0 1
R:R:S158 R:R:V107 3.23 23 No No 7 6 2 1
R:R:L162 R:R:V107 2.98 0 Yes No 5 6 2 1
L:L:?1 R:R:V107 7.41 0 Yes No 0 6 0 1
R:R:C110 R:R:W281 3.92 0 No Yes 6 8 1 2
L:L:?1 R:R:C110 10.52 0 Yes No 0 6 0 1
R:R:S111 R:R:T196 7.99 0 No No 7 6 2 1
L:L:?1 R:R:L182 4.59 0 Yes No 0 4 0 1
L:L:?1 R:R:T196 4.89 0 Yes No 0 6 0 1
R:R:F197 R:R:W281 3.01 5 Yes Yes 8 8 2 2
R:R:F197 R:R:F285 11.79 5 Yes No 8 6 2 1
R:R:F284 R:R:W281 3.01 5 Yes Yes 7 8 1 2
R:R:F285 R:R:W281 3.01 5 No Yes 6 8 1 2
R:R:F284 R:R:F302 7.5 5 Yes Yes 7 4 1 2
R:R:F284 R:R:T306 9.08 5 Yes No 7 4 1 2
L:L:?1 R:R:F284 4.04 0 Yes Yes 0 7 0 1
L:L:?1 R:R:F285 8.07 0 Yes No 0 6 0 1
R:R:F302 R:R:N288 4.83 5 Yes No 4 6 2 1
L:L:?1 R:R:N288 9.1 0 Yes No 0 6 0 1
R:R:F302 R:R:T306 5.19 5 Yes No 4 4 2 2
R:R:T306 R:R:Y310 4.99 5 No Yes 4 7 2 2
R:R:F284 R:R:L305 2.44 5 Yes No 7 4 1 2
StatisticsValue
Average Number Of Links8.00
Average Number Of Links With An Hub1.00
Average Interaction Strength7.06
Average Nodes In Shell20.00
Average Hubs In Shell8.00
Average Links In Shell27.00
Average Links Mediated by Hubs In Shell24.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links8.12
Average Number Of Links With An Hub3.00
Average Interaction Strength7.72
Average Nodes In Shell21.00
Average Hubs In Shell10.00
Average Links In Shell27.88
Average Links Mediated by Hubs In Shell25.12

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

missing image


Location of the nodes interacting with this ligand

(Click to enlarge 🔍)