CodeSWO
Name6-nonylpyridine-2,4-diol
Synonyms
Identifier6-nonylpyridine-2,4-diol
FormulaC14 H23 N O2
Molecular Weight237.338
SMILESCCCCCCCCCc1cc(cc(n1)O)O
PubChem127045422
Formal Charge0
Total Atoms40
Total Chiral Atoms0
Total Bonds40
Total Aromatic Bonds6
Networks1
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This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8J19 A Orphan A orphans GPR84 Homo sapiens PubChem 127045422 - Gi1/Beta1/Gamma2 3.23 2023-06-21 10.1038/s41467-023-38985-6

A 2D representation of the interactions of SWO in 8J19
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:V30 R:R:W26 8.58 2 Yes Yes 6 5 2 2
R:R:N357 R:R:W26 7.91 2 Yes Yes 8 5 2 2
R:R:W26 R:R:W360 4.69 2 Yes Yes 5 8 2 1
R:R:G27 R:R:V30 1.84 2 No Yes 5 6 2 2
R:R:G27 R:R:Q74 3.29 2 No Yes 5 8 2 2
R:R:G27 R:R:W360 2.81 2 No Yes 5 8 2 1
R:R:V30 R:R:W360 2.45 2 Yes Yes 6 8 2 1
R:R:L73 R:R:Y69 5.86 2 Yes Yes 8 8 2 2
R:R:Q74 R:R:Y69 4.51 2 Yes Yes 8 8 2 2
R:R:L100 R:R:Y69 5.86 2 Yes Yes 8 8 1 2
R:R:W360 R:R:Y69 6.75 2 Yes Yes 8 8 1 2
R:R:F96 R:R:L73 13.4 2 Yes Yes 6 8 2 2
R:R:L100 R:R:L73 6.92 2 Yes Yes 8 8 1 2
R:R:Q74 R:R:W360 9.86 2 Yes Yes 8 8 2 1
R:R:F96 R:R:S77 3.96 2 Yes No 6 7 2 2
R:R:S77 R:R:T167 6.4 2 No Yes 7 4 2 1
R:R:W360 R:R:Y81 8.68 2 Yes Yes 8 5 1 2
R:R:F96 R:R:L100 2.44 2 Yes Yes 6 8 2 1
R:R:F96 R:R:T167 2.59 2 Yes Yes 6 4 2 1
R:R:F101 R:R:L100 4.87 2 Yes Yes 7 8 1 1
R:R:L100 R:R:N104 2.75 2 Yes Yes 8 7 1 1
L:L:?1 R:R:L100 8.98 2 Yes Yes 0 8 0 1
R:R:F101 R:R:F152 15 2 Yes Yes 7 8 1 1
R:R:F101 R:R:Y159 2.06 2 Yes Yes 7 5 1 2
R:R:F101 R:R:S169 7.93 2 Yes No 7 4 1 1
R:R:F101 R:R:F170 8.57 2 Yes Yes 7 6 1 2
L:L:?1 R:R:F101 7.9 2 Yes Yes 0 7 0 1
R:R:N104 R:R:Y332 4.65 2 Yes Yes 7 8 1 2
R:R:N104 R:R:T359 2.92 2 Yes Yes 7 8 1 1
L:L:?1 R:R:N104 18.81 2 Yes Yes 0 7 0 1
R:R:L109 R:R:S105 4.5 2 No Yes 6 7 2 2
R:R:F152 R:R:S105 5.28 2 Yes Yes 8 7 1 2
R:R:S105 R:R:Y186 7.63 2 Yes Yes 7 8 2 1
R:R:I108 R:R:Y186 4.84 2 Yes Yes 8 8 1 1
R:R:F328 R:R:I108 3.77 2 Yes Yes 9 8 2 1
R:R:I108 R:R:Y332 15.71 2 Yes Yes 8 8 1 2
L:L:?1 R:R:I108 2.06 2 Yes Yes 0 8 0 1
R:R:L109 R:R:Y186 3.52 2 No Yes 6 8 2 1
R:R:F152 R:R:S151 7.93 2 Yes Yes 8 7 1 2
R:R:L182 R:R:S151 6.01 2 Yes Yes 8 7 1 2
R:R:S151 R:R:Y186 2.54 2 Yes Yes 7 8 2 1
R:R:F152 R:R:Y159 4.13 2 Yes Yes 8 5 1 2
R:R:F152 R:R:L182 3.65 2 Yes Yes 8 8 1 1
L:L:?1 R:R:F152 6.15 2 Yes Yes 0 8 0 1
R:R:F170 R:R:Y159 2.06 2 Yes Yes 6 5 2 2
R:R:V162 R:R:V165 3.21 2 No Yes 3 4 2 1
R:R:R172 R:R:V162 3.92 2 Yes No 5 3 1 2
R:R:T167 R:R:V165 3.17 2 Yes Yes 4 4 1 1
R:R:R172 R:R:V165 3.92 2 Yes Yes 5 4 1 1
L:L:?1 R:R:V165 8.59 2 Yes Yes 0 4 0 1
L:L:?1 R:R:T167 5.31 2 Yes Yes 0 4 0 1
L:L:?1 R:R:S169 8.66 2 Yes No 0 4 0 1
R:R:F170 R:R:R172 10.69 2 Yes Yes 6 5 2 1
R:R:F170 R:R:T179 15.56 2 Yes No 6 6 2 2
R:R:F170 R:R:M183 3.73 2 Yes Yes 6 8 2 1
R:R:F335 R:R:R172 3.21 2 Yes Yes 8 5 1 1
R:R:N339 R:R:R172 6.03 2 Yes Yes 7 5 2 1
R:R:R172 R:R:V345 2.62 2 Yes No 5 4 1 2
L:L:?1 R:R:R172 4.38 2 Yes Yes 0 5 0 1
R:R:L182 R:R:Y178 4.69 2 Yes No 8 8 1 2
R:R:M183 R:R:T179 3.01 2 Yes No 8 6 1 2
R:R:L182 R:R:Y186 3.52 2 Yes Yes 8 8 1 1
L:L:?1 R:R:L182 2 2 Yes Yes 0 8 0 1
R:R:L336 R:R:M183 4.24 2 No Yes 7 8 1 1
R:R:M183 R:R:N339 2.8 2 Yes Yes 8 7 1 2
R:R:I340 R:R:M183 4.37 0 No Yes 6 8 2 1
L:L:?1 R:R:M183 2.04 2 Yes Yes 0 8 0 1
L:L:?1 R:R:Y186 9.3 2 Yes Yes 0 8 0 1
R:R:F328 R:R:Y332 6.19 2 Yes Yes 9 8 2 2
R:R:T359 R:R:Y332 2.5 2 Yes Yes 8 8 1 2
R:R:F335 R:R:N339 10.87 2 Yes Yes 8 7 1 2
R:R:A355 R:R:F335 4.16 0 No Yes 6 8 2 1
L:L:?1 R:R:F335 14.05 2 Yes Yes 0 8 0 1
L:L:?1 R:R:L336 2 2 Yes No 0 7 0 1
R:R:A356 R:R:W360 3.89 2 No Yes 6 8 1 1
L:L:?1 R:R:A356 3.41 2 Yes No 0 6 0 1
R:R:N357 R:R:W360 9.04 2 Yes Yes 8 8 2 1
R:R:T359 R:R:W360 2.43 2 Yes Yes 8 8 1 1
L:L:?1 R:R:T359 11.69 2 Yes Yes 0 8 0 1
L:L:?1 R:R:W360 5.75 2 Yes Yes 0 8 0 1
StatisticsValue
Average Number Of Links17.00
Average Number Of Links With An Hub14.00
Average Interaction Strength7.12
Average Nodes In Shell42.00
Average Hubs In Shell30.00
Average Links In Shell80.00
Average Links Mediated by Hubs In Shell80.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links17.00
Average Number Of Links With An Hub14.00
Average Interaction Strength7.12
Average Nodes In Shell42.00
Average Hubs In Shell30.00
Average Links In Shell80.00
Average Links Mediated by Hubs In Shell80.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)