CodeT4G
Name6-(2,6-dimethylpyridin-4-yl)-5-phenyl-1,2,4-triazin-3-amine
Synonyms
Identifier6-(2,6-dimethylpyridin-4-yl)-5-phenyl-1,2,4-triazin-3-amine
FormulaC16 H15 N5
Molecular Weight277.324
SMILESCc1cc(cc(n1)C)c2c(nc(nn2)N)c3ccccc3
PubChem56844240
Formal Charge0
Total Atoms36
Total Chiral Atoms0
Total Bonds38
Total Aromatic Bonds18
Networks1
 missing image

This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
3UZA A Nucleotide Adenosine A2A Homo sapiens GTPL9236 - - 3.27 2012-03-21 10.1021/jm201376w

A 2D representation of the interactions of T4G in 3UZA
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:E13 R:R:I60 8.2 1 Yes Yes 6 6 2 2
R:R:E13 R:R:H278 11.08 1 Yes Yes 6 6 2 1
R:R:H278 R:R:I60 5.3 1 Yes Yes 6 6 1 2
R:R:F168 R:R:I66 3.77 0 Yes No 4 4 1 2
R:R:L85 R:R:M177 4.24 1 No Yes 4 6 2 1
R:R:L85 R:R:N181 8.24 1 No No 4 5 2 2
R:R:F168 R:R:V172 11.8 0 Yes No 4 3 1 2
L:L:?1 R:R:F168 25.93 1 Yes Yes 0 4 0 1
R:R:M177 R:R:Y176 3.59 1 Yes Yes 6 6 1 2
R:R:N181 R:R:Y176 8.14 1 No Yes 5 6 2 2
R:R:M177 R:R:N181 4.21 1 Yes No 6 5 1 2
L:L:?1 R:R:M177 6.45 1 Yes Yes 0 6 0 1
R:R:F182 R:R:V186 3.93 1 Yes No 5 7 2 2
R:R:F182 R:R:H250 23.76 1 Yes No 5 6 2 1
R:R:H250 R:R:V186 4.15 1 No No 6 7 1 2
L:L:?1 R:R:L249 22.1 1 Yes No 0 5 0 1
L:L:?1 R:R:H250 8.8 1 Yes No 0 6 0 1
L:L:?1 R:R:N253 17.75 1 Yes No 0 5 0 1
R:R:I274 R:R:M270 5.83 1 No No 4 4 1 2
R:R:H278 R:R:I274 3.98 1 Yes No 6 4 1 1
L:L:?1 R:R:I274 19.53 1 Yes No 0 4 0 1
L:L:?1 R:R:H278 5.86 1 Yes Yes 0 6 0 1
R:R:A63 R:R:H278 2.93 0 No Yes 5 6 2 1
R:R:A81 R:R:F168 2.77 0 No Yes 5 4 2 1
StatisticsValue
Average Number Of Links7.00
Average Number Of Links With An Hub3.00
Average Interaction Strength15.20
Average Nodes In Shell20.00
Average Hubs In Shell8.00
Average Links In Shell24.00
Average Links Mediated by Hubs In Shell21.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links7.00
Average Number Of Links With An Hub3.00
Average Interaction Strength15.20
Average Nodes In Shell20.00
Average Hubs In Shell8.00
Average Links In Shell24.00
Average Links Mediated by Hubs In Shell21.00

missing image


Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

missing image


Location of the nodes interacting with this ligand

(Click to enlarge 🔍)