CodeUYA
Name(4R)-4-hydroxy-D-proline
Synonyms
Identifier
FormulaC5 H9 N O3
Molecular Weight131.13
SMILES
PubChem440014
Formal Charge0
Total Atoms18
Total Chiral Atoms2
Total Bonds18
Total Aromatic Bonds0
Networks2
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This ligand is also present in the following 2 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8XGO A Peptide Kisspeptin Kiss1 Homo Sapiens TAK448 - chim(NtGi1-Gq)/Beta1/Gamma2 2.68 2024-10-30 doi.org/10.1126/sciadv.adn7771

A 2D representation of the interactions of UYA in 8XGO
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:N4 R:R:L102 6.87 3 Yes No 0 5 1 2
L:L:?5 R:R:L102 5.11 3 Yes No 0 5 1 2
R:R:Y103 R:R:Y302 7.94 3 Yes Yes 5 5 2 2
L:L:?5 R:R:Y103 8.66 3 Yes Yes 0 5 1 2
L:L:N4 R:R:G107 5.09 3 Yes No 0 5 1 2
R:R:S184 R:R:Y190 5.09 0 No Yes 3 4 2 1
R:R:R188 R:R:Y190 14.4 0 No Yes 2 4 2 1
L:L:?3 R:R:Y190 8.05 3 Yes Yes 0 4 0 1
L:L:N4 R:R:Y190 4.65 3 Yes Yes 0 4 1 1
R:R:F282 R:R:K305 12.41 0 No No 5 4 2 2
L:L:F6 R:R:F282 4.29 3 Yes No 0 5 1 2
L:L:F6 R:R:R297 17.1 3 Yes No 0 2 1 2
L:L:Y2 R:R:Y302 3.97 0 No Yes 0 5 1 2
L:L:?5 R:R:K305 9.11 3 Yes No 0 4 1 2
L:L:?3 L:L:Y2 11.07 3 Yes No 0 0 0 1
L:L:?3 L:L:N4 8.25 3 Yes Yes 0 0 0 1
L:L:?3 L:L:?5 15.36 3 Yes Yes 0 0 0 1
L:L:?3 L:L:F6 4.18 3 Yes Yes 0 0 0 1
L:L:?5 L:L:N4 8.87 3 Yes Yes 0 0 1 1
L:L:?5 L:L:F6 15.74 3 Yes Yes 0 0 1 1
StatisticsValue
Average Number Of Links5.00
Average Number Of Links With An Hub4.00
Average Interaction Strength9.38
Average Nodes In Shell15.00
Average Hubs In Shell7.00
Average Links In Shell20.00
Average Links Mediated by Hubs In Shell19.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links5.00
Average Number Of Links With An Hub4.00
Average Interaction Strength9.38
Average Nodes In Shell15.50
Average Hubs In Shell7.00
Average Links In Shell21.00
Average Links Mediated by Hubs In Shell19.50

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)