CodeWA6
Name(2S)-2-azanyl-2-cyclopropyl-2-(4-phosphonophenyl)ethanoic acid
Synonyms
Identifier
FormulaC11 H14 N O5 P
Molecular Weight271.206
SMILES
PubChem11459929
Formal Charge0
Total Atoms32
Total Chiral Atoms1
Total Bonds33
Total Aromatic Bonds6
Networks1
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This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8WGD C Aminoacid Metabotropic Glutamate mGlu4; mGlu2 Homo Sapiens WAG; WA6 - - 4.45 2024-11-27 doi.org/10.1038/s41467-024-54744-7

A 2D representation of the interactions of WA6 in 8WGD
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?1 R:R:T182 31.4 43 Yes No 0 8 0 1
R:R:F284 R:R:Q205 4.68 0 Yes No 8 9 1 2
R:R:D312 R:R:Q205 13.05 43 No No 8 9 1 2
L:L:?1 R:R:Y230 53.07 43 Yes No 0 7 0 1
R:R:F284 R:R:G234 7.53 0 Yes No 8 7 1 2
R:R:F284 R:R:S311 17.18 0 Yes No 8 8 1 2
L:L:?1 R:R:F284 6.49 43 Yes Yes 0 8 0 1
R:R:D312 R:R:S313 5.89 43 No No 8 6 1 1
L:L:?1 R:R:D312 3.61 43 Yes No 0 8 0 1
L:L:?1 R:R:S313 5 43 Yes No 0 6 0 1
R:R:F284 R:R:G231 3.01 0 Yes No 8 8 1 2
L:L:?1 R:R:S159 2 43 Yes No 0 9 0 1
StatisticsValue
Average Number Of Links6.00
Average Number Of Links With An Hub1.00
Average Interaction Strength16.93
Average Nodes In Shell11.00
Average Hubs In Shell2.00
Average Links In Shell12.00
Average Links Mediated by Hubs In Shell10.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links6.00
Average Number Of Links With An Hub1.00
Average Interaction Strength16.93
Average Nodes In Shell11.00
Average Hubs In Shell2.00
Average Links In Shell12.00
Average Links Mediated by Hubs In Shell10.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)