CodeWPT
Name3-(4-{[(3-phenoxyphenyl)methyl]amino}phenyl)propanoic acid
Synonyms
Identifier3-[4-[(3-phenoxyphenyl)methylamino]phenyl]propanoic acid
FormulaC22 H21 N O3
Molecular Weight347.407
SMILESc1ccc(cc1)Oc2cccc(c2)CNc3ccc(cc3)CCC(=O)O
PubChem11595431
Formal Charge0
Total Atoms47
Total Chiral Atoms0
Total Bonds49
Total Aromatic Bonds18
Networks1
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This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8H4K A Lipid Free fatty acid FFA4 Homo sapiens GW9508 - chim(NtGi1-Gs-CtGq)/Beta1/Gamma2 3.1 2023-06-21 10.1038/s41422-023-00835-x

A 2D representation of the interactions of WPT in 8H4K
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:F25 R:R:F27 7.5 0 Yes Yes 5 5 2 1
R:R:F25 R:R:I287 5.02 0 Yes Yes 5 5 2 1
R:R:F177 R:R:F27 6.43 1 Yes Yes 5 5 1 1
R:R:F27 R:R:T195 2.59 1 Yes Yes 5 4 1 2
R:R:F27 R:R:F303 2.14 1 Yes Yes 5 4 1 1
L:L:?1 R:R:F27 3.09 1 Yes Yes 0 5 0 1
R:R:F115 R:R:F28 3.22 1 Yes Yes 5 8 1 2
R:R:F28 R:R:F303 3.22 1 Yes Yes 8 4 2 1
R:R:F28 R:R:V307 2.62 1 Yes Yes 8 5 2 1
R:R:F88 R:R:M118 3.73 1 Yes Yes 7 7 1 1
R:R:F88 R:R:S121 5.28 1 Yes Yes 7 8 1 2
R:R:F88 R:R:T310 2.59 1 Yes No 7 8 1 2
R:R:F311 R:R:F88 9.65 1 Yes Yes 7 7 2 1
L:L:?1 R:R:F88 2.06 1 Yes Yes 0 7 0 1
R:R:A91 R:R:M118 3.22 0 No Yes 6 7 2 1
R:R:F115 R:R:L114 2.44 1 Yes No 5 6 1 2
R:R:F115 R:R:M118 2.49 1 Yes Yes 5 7 1 1
R:R:F115 R:R:L173 3.65 1 Yes Yes 5 5 1 1
R:R:F115 R:R:F177 20.36 1 Yes Yes 5 5 1 1
R:R:C194 R:R:F115 2.79 1 Yes Yes 9 5 2 1
L:L:?1 R:R:F115 2.06 1 Yes Yes 0 5 0 1
R:R:F311 R:R:M118 2.49 1 Yes Yes 7 7 2 1
L:L:?1 R:R:M118 9.57 1 Yes Yes 0 7 0 1
R:R:A170 R:R:T119 3.36 0 No Yes 7 5 2 1
R:R:L173 R:R:T119 4.42 1 Yes Yes 5 5 1 1
R:R:F211 R:R:T119 2.59 1 Yes Yes 5 5 1 1
L:L:?1 R:R:T119 3.74 1 Yes Yes 0 5 0 1
R:R:G122 R:R:S121 1.86 0 No Yes 7 8 1 2
R:R:G122 R:R:T125 1.82 0 No No 7 9 1 2
L:L:?1 R:R:G122 5.79 1 Yes No 0 7 0 1
R:R:F211 R:R:S123 2.64 1 Yes No 5 6 1 2
R:R:N215 R:R:S123 2.98 1 No No 6 6 2 2
R:R:I126 R:R:P219 3.39 1 Yes No 8 9 1 2
R:R:F273 R:R:I126 2.51 1 Yes Yes 9 8 2 1
R:R:I126 R:R:W277 5.87 1 Yes Yes 8 9 1 1
L:L:?1 R:R:I126 3.62 1 Yes Yes 0 8 0 1
R:R:P172 R:R:W198 4.05 1 Yes Yes 8 7 2 1
R:R:P172 R:R:W207 4.05 1 Yes Yes 8 6 2 2
R:R:F177 R:R:L173 6.09 1 Yes Yes 5 5 1 1
R:R:L173 R:R:W207 4.56 1 Yes Yes 5 6 1 2
L:L:?1 R:R:L173 5.85 1 Yes Yes 0 5 0 1
R:R:C194 R:R:F177 2.79 1 Yes Yes 9 5 2 1
R:R:F177 R:R:L196 20.7 1 Yes No 5 5 1 1
L:L:?1 R:R:F177 3.09 1 Yes Yes 0 5 0 1
R:R:L196 R:R:W198 9.11 1 No Yes 5 7 1 1
L:L:?1 R:R:L196 2.34 1 Yes No 0 5 0 1
R:R:P199 R:R:W198 5.4 0 No Yes 6 7 2 1
R:R:E204 R:R:W198 32.71 1 No Yes 5 7 1 1
R:R:W198 R:R:W207 5.62 1 Yes Yes 7 6 1 2
L:L:?1 R:R:W198 4.82 1 Yes Yes 0 7 0 1
R:R:E204 R:R:L288 2.65 1 No No 5 4 1 2
L:L:?1 R:R:E204 5.6 1 Yes No 0 5 0 1
R:R:D208 R:R:W207 4.47 0 No Yes 5 6 1 2
R:R:F211 R:R:W207 5.01 1 Yes Yes 5 6 1 2
R:R:D208 R:R:L288 6.79 0 No No 5 4 1 2
L:L:?1 R:R:D208 10.33 1 Yes No 0 5 0 1
R:R:F211 R:R:N215 8.46 1 Yes No 5 6 1 2
L:L:?1 R:R:F211 6.18 1 Yes Yes 0 5 0 1
R:R:I281 R:R:V212 3.07 0 Yes No 7 6 1 2
R:R:F216 R:R:F273 3.22 1 Yes Yes 8 9 2 2
R:R:F216 R:R:W277 2 1 Yes Yes 8 9 2 1
R:R:F216 R:R:I281 8.79 1 Yes Yes 8 7 2 1
R:R:N313 R:R:W277 23.73 0 No Yes 9 9 2 1
L:L:?1 R:R:W277 5.78 1 Yes Yes 0 9 0 1
R:R:I280 R:R:I281 2.94 0 No Yes 6 7 2 1
R:R:I280 R:R:T310 3.04 0 No No 6 8 2 2
L:L:?1 R:R:I281 2.41 1 Yes Yes 0 7 0 1
R:R:F303 R:R:T283 2.59 1 Yes No 4 5 1 2
L:L:?1 R:R:I284 7.24 1 Yes No 0 5 0 1
R:R:F303 R:R:I287 2.51 1 Yes Yes 4 5 1 1
L:L:?1 R:R:I287 6.04 1 Yes Yes 0 5 0 1
R:R:F303 R:R:V307 3.93 1 Yes Yes 4 5 1 1
L:L:?1 R:R:F303 3.09 1 Yes Yes 0 4 0 1
R:R:F311 R:R:V307 5.24 1 Yes Yes 7 5 2 1
L:L:?1 R:R:V307 2.52 1 Yes Yes 0 5 0 1
R:R:I287 R:R:N291 1.42 1 Yes No 5 2 1 2
StatisticsValue
Average Number Of Links20.00
Average Number Of Links With An Hub15.00
Average Interaction Strength4.76
Average Nodes In Shell46.00
Average Hubs In Shell26.00
Average Links In Shell76.00
Average Links Mediated by Hubs In Shell71.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links20.00
Average Number Of Links With An Hub15.00
Average Interaction Strength4.76
Average Nodes In Shell46.00
Average Hubs In Shell26.00
Average Links In Shell76.00
Average Links Mediated by Hubs In Shell71.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)