| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 8X0B | C | Aminoacid | Metabotropic Glutamate | mGlu5; mGlu5 | Homo Sapiens | Quisqualate | VU0424465 | - | 3.1 | 2024-11-06 | doi.org/10.1038/s41467-024-55439-9 |
|
A 2D representation of the interactions of XQT in 8X0B
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | R:R:L627 | R:R:S654 | 4.5 | 0 | Yes | Yes | 5 | 7 | 2 | 1 | | R:R:G628 | R:R:S654 | 3.71 | 5 | No | Yes | 6 | 7 | 1 | 1 | | R:R:G628 | W:W:?1 | 2.96 | 5 | No | Yes | 6 | 0 | 1 | 0 | | R:R:A810 | R:R:Y629 | 8.01 | 0 | No | No | 7 | 8 | 1 | 2 | | R:R:I651 | R:R:M802 | 5.83 | 0 | No | Yes | 7 | 8 | 2 | 1 | | R:R:P655 | R:R:S654 | 3.56 | 5 | No | Yes | 8 | 7 | 1 | 1 | | R:R:S654 | W:W:?1 | 6.92 | 5 | Yes | Yes | 7 | 0 | 1 | 0 | | R:R:N747 | R:R:P655 | 11.4 | 0 | No | No | 7 | 8 | 2 | 1 | | R:R:P655 | W:W:?1 | 9.46 | 5 | No | Yes | 8 | 0 | 1 | 0 | | R:R:S658 | R:R:Y659 | 3.82 | 0 | No | Yes | 6 | 7 | 2 | 1 | | R:R:I751 | R:R:Y659 | 4.84 | 0 | Yes | Yes | 8 | 7 | 2 | 1 | | R:R:T781 | R:R:Y659 | 6.24 | 0 | No | Yes | 9 | 7 | 2 | 1 | | R:R:L813 | R:R:Y659 | 4.69 | 0 | No | Yes | 7 | 7 | 2 | 1 | | R:R:Y659 | W:W:?1 | 5.4 | 0 | Yes | Yes | 7 | 0 | 1 | 0 | | R:R:V740 | R:R:Y792 | 3.79 | 0 | No | Yes | 8 | 8 | 2 | 1 | | R:R:L744 | R:R:W785 | 3.42 | 5 | No | Yes | 8 | 8 | 1 | 1 | | R:R:L744 | W:W:?1 | 7.97 | 5 | No | Yes | 8 | 0 | 1 | 0 | | R:R:N747 | R:R:W785 | 4.52 | 0 | No | Yes | 7 | 8 | 2 | 1 | | R:R:I751 | R:R:W785 | 7.05 | 0 | Yes | Yes | 8 | 8 | 2 | 1 | | R:R:S809 | R:R:W785 | 7.41 | 5 | No | Yes | 9 | 8 | 1 | 1 | | R:R:W785 | W:W:?1 | 18.37 | 5 | Yes | Yes | 8 | 0 | 1 | 0 | | R:R:F788 | R:R:T801 | 5.19 | 5 | No | No | 9 | 8 | 2 | 2 | | R:R:F788 | R:R:S805 | 3.96 | 5 | No | No | 9 | 8 | 2 | 1 | | R:R:F793 | R:R:Y792 | 11.35 | 0 | No | Yes | 6 | 8 | 2 | 1 | | R:R:K798 | R:R:Y792 | 11.94 | 0 | No | Yes | 6 | 8 | 2 | 1 | | R:R:T801 | R:R:Y792 | 4.99 | 5 | No | Yes | 8 | 8 | 2 | 1 | | R:R:M802 | R:R:Y792 | 4.79 | 5 | Yes | Yes | 8 | 8 | 1 | 1 | | R:R:Y792 | W:W:?1 | 8.78 | 5 | Yes | Yes | 8 | 0 | 1 | 0 | | R:R:M802 | R:R:V806 | 3.04 | 5 | Yes | No | 8 | 8 | 1 | 1 | | R:R:M802 | W:W:?1 | 9.77 | 5 | Yes | Yes | 8 | 0 | 1 | 0 | | R:R:S805 | W:W:?1 | 12.11 | 0 | No | Yes | 8 | 0 | 1 | 0 | | R:R:V806 | W:W:?1 | 11.16 | 5 | No | Yes | 8 | 0 | 1 | 0 | | R:R:S809 | W:W:?1 | 7.79 | 5 | No | Yes | 9 | 0 | 1 | 0 | | R:R:A810 | W:W:?1 | 4.54 | 0 | No | Yes | 7 | 0 | 1 | 0 | | R:R:L635 | R:R:M802 | 2.83 | 0 | No | Yes | 7 | 8 | 2 | 1 | | R:R:C631 | R:R:G628 | 1.96 | 0 | No | No | 7 | 6 | 2 | 1 | | R:R:G745 | R:R:L744 | 1.71 | 0 | No | No | 5 | 8 | 2 | 1 | |
| Statistics | Value |
|---|
| Average Number Of Links | 12.00 | | Average Number Of Links With An Hub | 5.00 | | Average Interaction Strength | 8.77 | | Average Nodes In Shell | 29.00 | | Average Hubs In Shell | 8.00 | | Average Links In Shell | 37.00 | | Average Links Mediated by Hubs In Shell | 31.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of XQT in 8X0B
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | S:S:I625 | S:S:T594 | 3.04 | 0 | No | Yes | 8 | 7 | 1 | 2 | | S:S:I625 | S:S:L814 | 7.14 | 0 | No | No | 8 | 8 | 1 | 2 | | S:S:I625 | X:X:?1 | 4.11 | 0 | No | Yes | 8 | 0 | 1 | 0 | | S:S:I651 | S:S:M802 | 4.37 | 0 | No | No | 7 | 8 | 2 | 1 | | S:S:P655 | S:S:S654 | 3.56 | 0 | No | No | 8 | 7 | 1 | 2 | | S:S:N747 | S:S:P655 | 9.77 | 3 | Yes | No | 7 | 8 | 2 | 1 | | S:S:P655 | X:X:?1 | 12.3 | 0 | No | Yes | 8 | 0 | 1 | 0 | | S:S:L813 | S:S:S658 | 3 | 3 | Yes | No | 7 | 6 | 1 | 1 | | S:S:S658 | X:X:?1 | 6.06 | 3 | No | Yes | 6 | 0 | 1 | 0 | | S:S:N747 | S:S:Y659 | 4.65 | 3 | Yes | Yes | 7 | 7 | 2 | 1 | | S:S:I751 | S:S:Y659 | 10.88 | 3 | No | Yes | 8 | 7 | 2 | 1 | | S:S:M778 | S:S:Y659 | 3.59 | 3 | Yes | Yes | 9 | 7 | 2 | 1 | | S:S:T781 | S:S:Y659 | 4.99 | 0 | No | Yes | 9 | 7 | 2 | 1 | | S:S:W785 | S:S:Y659 | 2.89 | 3 | Yes | Yes | 8 | 7 | 1 | 1 | | S:S:L813 | S:S:Y659 | 5.86 | 3 | Yes | Yes | 7 | 7 | 1 | 1 | | S:S:Y659 | X:X:?1 | 6.08 | 3 | Yes | Yes | 7 | 0 | 1 | 0 | | S:S:L744 | S:S:W785 | 3.42 | 3 | Yes | Yes | 8 | 8 | 1 | 1 | | S:S:L744 | X:X:?1 | 7.18 | 3 | Yes | Yes | 8 | 0 | 1 | 0 | | S:S:N747 | S:S:W785 | 9.04 | 3 | Yes | Yes | 7 | 8 | 2 | 1 | | S:S:I751 | S:S:M778 | 5.83 | 3 | No | Yes | 8 | 9 | 2 | 2 | | S:S:S809 | S:S:W785 | 4.94 | 3 | No | Yes | 9 | 8 | 1 | 1 | | S:S:W785 | X:X:?1 | 20.34 | 3 | Yes | Yes | 8 | 0 | 1 | 0 | | S:S:P790 | S:S:V789 | 3.53 | 0 | No | Yes | 9 | 7 | 2 | 1 | | S:S:F793 | S:S:V789 | 10.49 | 0 | No | Yes | 6 | 7 | 2 | 1 | | S:S:V789 | X:X:?1 | 4.29 | 0 | Yes | Yes | 7 | 0 | 1 | 0 | | S:S:F793 | S:S:Y792 | 4.13 | 0 | No | Yes | 6 | 8 | 2 | 1 | | S:S:K798 | S:S:Y792 | 10.75 | 0 | No | Yes | 6 | 8 | 2 | 1 | | S:S:T801 | S:S:Y792 | 3.75 | 3 | Yes | Yes | 8 | 8 | 2 | 1 | | S:S:M802 | S:S:Y792 | 9.58 | 3 | No | Yes | 8 | 8 | 1 | 1 | | S:S:Y792 | X:X:?1 | 5.4 | 3 | Yes | Yes | 8 | 0 | 1 | 0 | | S:S:M802 | X:X:?1 | 11.4 | 3 | No | Yes | 8 | 0 | 1 | 0 | | S:S:S805 | X:X:?1 | 12.11 | 0 | No | Yes | 8 | 0 | 1 | 0 | | S:S:V806 | X:X:?1 | 4.29 | 0 | No | Yes | 8 | 0 | 1 | 0 | | S:S:S809 | X:X:?1 | 8.65 | 3 | No | Yes | 9 | 0 | 1 | 0 | | S:S:L813 | S:S:M817 | 4.24 | 3 | Yes | Yes | 7 | 8 | 1 | 2 | | S:S:L813 | X:X:?1 | 3.19 | 3 | Yes | Yes | 7 | 0 | 1 | 0 | | S:S:G745 | S:S:L744 | 1.71 | 0 | No | Yes | 5 | 8 | 2 | 1 | | S:S:L744 | S:S:V740 | 1.49 | 3 | Yes | No | 8 | 8 | 1 | 2 | | S:S:L786 | S:S:V789 | 1.49 | 0 | No | Yes | 6 | 7 | 2 | 1 | |
| Statistics | Value |
|---|
| Average Number Of Links | 13.00 | | Average Number Of Links With An Hub | 6.00 | | Average Interaction Strength | 8.11 | | Average Nodes In Shell | 30.00 | | Average Hubs In Shell | 12.00 | | Average Links In Shell | 39.00 | | Average Links Mediated by Hubs In Shell | 36.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 8X0C | C | Aminoacid | Metabotropic Glutamate | mGlu5; mGlu5 | Homo Sapiens | Quisqualate | VU0424465 | - | 3.2 | 2024-11-06 | doi.org/10.1038/s41467-024-55439-9 |
|
A 2D representation of the interactions of XQT in 8X0C
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | R:R:L627 | R:R:S654 | 6.01 | 0 | No | Yes | 5 | 7 | 2 | 1 | | R:R:G628 | R:R:S654 | 3.71 | 0 | No | Yes | 6 | 7 | 2 | 1 | | R:R:A810 | R:R:Y629 | 6.67 | 0 | No | No | 7 | 8 | 1 | 2 | | R:R:I651 | R:R:M802 | 5.83 | 0 | No | Yes | 7 | 8 | 2 | 1 | | R:R:P655 | R:R:S654 | 5.34 | 4 | No | Yes | 8 | 7 | 1 | 1 | | R:R:S654 | W:W:?1 | 6.92 | 4 | Yes | Yes | 7 | 0 | 1 | 0 | | R:R:N747 | R:R:P655 | 4.89 | 4 | Yes | No | 7 | 8 | 2 | 1 | | R:R:P655 | W:W:?1 | 12.3 | 4 | No | Yes | 8 | 0 | 1 | 0 | | R:R:L813 | R:R:S658 | 3 | 0 | No | No | 7 | 6 | 2 | 1 | | R:R:S658 | W:W:?1 | 7.79 | 0 | No | Yes | 6 | 0 | 1 | 0 | | R:R:I751 | R:R:Y659 | 8.46 | 0 | No | No | 8 | 7 | 2 | 1 | | R:R:T781 | R:R:Y659 | 6.24 | 0 | No | No | 9 | 7 | 2 | 1 | | R:R:Y659 | W:W:?1 | 7.43 | 0 | No | Yes | 7 | 0 | 1 | 0 | | R:R:L744 | R:R:W785 | 3.42 | 4 | No | Yes | 8 | 8 | 1 | 1 | | R:R:L744 | W:W:?1 | 7.18 | 4 | No | Yes | 8 | 0 | 1 | 0 | | R:R:N747 | R:R:W785 | 3.39 | 4 | Yes | Yes | 7 | 8 | 2 | 1 | | R:R:S809 | R:R:W785 | 7.41 | 4 | No | Yes | 9 | 8 | 1 | 1 | | R:R:W785 | W:W:?1 | 18.37 | 4 | Yes | Yes | 8 | 0 | 1 | 0 | | R:R:F788 | R:R:I791 | 5.02 | 4 | No | Yes | 9 | 7 | 1 | 2 | | R:R:F788 | R:R:S805 | 3.96 | 4 | No | No | 9 | 8 | 1 | 1 | | R:R:F788 | W:W:?1 | 4.91 | 4 | No | Yes | 9 | 0 | 1 | 0 | | R:R:M802 | R:R:Y792 | 5.99 | 4 | Yes | Yes | 8 | 8 | 1 | 2 | | R:R:M802 | R:R:V806 | 3.04 | 4 | Yes | No | 8 | 8 | 1 | 1 | | R:R:M802 | W:W:?1 | 8.96 | 4 | Yes | Yes | 8 | 0 | 1 | 0 | | R:R:S805 | R:R:V806 | 3.23 | 4 | No | No | 8 | 8 | 1 | 1 | | R:R:S805 | W:W:?1 | 15.57 | 4 | No | Yes | 8 | 0 | 1 | 0 | | R:R:V806 | W:W:?1 | 6.87 | 4 | No | Yes | 8 | 0 | 1 | 0 | | R:R:S809 | W:W:?1 | 8.65 | 4 | No | Yes | 9 | 0 | 1 | 0 | | R:R:L635 | R:R:M802 | 2.83 | 0 | Yes | Yes | 7 | 8 | 2 | 1 | | R:R:A810 | W:W:?1 | 2.72 | 0 | No | Yes | 7 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 12.00 | | Average Number Of Links With An Hub | 3.00 | | Average Interaction Strength | 8.97 | | Average Nodes In Shell | 24.00 | | Average Hubs In Shell | 8.00 | | Average Links In Shell | 30.00 | | Average Links Mediated by Hubs In Shell | 24.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of XQT in 8X0C
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | S:S:I621 | S:S:S658 | 4.64 | 0 | No | Yes | 8 | 6 | 2 | 1 | | S:S:L627 | S:S:S654 | 9.01 | 0 | No | Yes | 5 | 7 | 2 | 1 | | S:S:G628 | S:S:S654 | 3.71 | 0 | No | Yes | 6 | 7 | 2 | 1 | | S:S:T632 | S:S:Y629 | 3.75 | 34 | Yes | Yes | 7 | 8 | 2 | 2 | | S:S:A810 | S:S:Y629 | 6.67 | 0 | No | Yes | 7 | 8 | 1 | 2 | | S:S:T632 | S:S:V806 | 3.17 | 34 | Yes | No | 7 | 8 | 2 | 1 | | S:S:I651 | S:S:M802 | 2.92 | 0 | No | No | 7 | 8 | 2 | 1 | | S:S:P655 | S:S:S654 | 3.56 | 7 | No | Yes | 8 | 7 | 1 | 1 | | S:S:S654 | X:X:?1 | 3.46 | 7 | Yes | Yes | 7 | 0 | 1 | 0 | | S:S:N747 | S:S:P655 | 4.89 | 0 | No | No | 7 | 8 | 2 | 1 | | S:S:P655 | X:X:?1 | 10.41 | 7 | No | Yes | 8 | 0 | 1 | 0 | | S:S:L813 | S:S:S658 | 3 | 0 | No | Yes | 7 | 6 | 2 | 1 | | S:S:S658 | X:X:?1 | 3.46 | 0 | Yes | Yes | 6 | 0 | 1 | 0 | | S:S:L750 | S:S:Y659 | 3.52 | 0 | No | Yes | 9 | 7 | 2 | 1 | | S:S:I751 | S:S:Y659 | 3.63 | 7 | Yes | Yes | 8 | 7 | 2 | 1 | | S:S:M778 | S:S:Y659 | 3.59 | 7 | Yes | Yes | 9 | 7 | 2 | 1 | | S:S:T781 | S:S:Y659 | 4.99 | 7 | No | Yes | 9 | 7 | 2 | 1 | | S:S:L813 | S:S:Y659 | 5.86 | 0 | No | Yes | 7 | 7 | 2 | 1 | | S:S:Y659 | X:X:?1 | 5.4 | 7 | Yes | Yes | 7 | 0 | 1 | 0 | | S:S:L744 | X:X:?1 | 4.78 | 0 | No | Yes | 8 | 0 | 1 | 0 | | S:S:N747 | S:S:W785 | 5.65 | 0 | No | No | 7 | 8 | 2 | 1 | | S:S:I751 | S:S:M778 | 2.92 | 7 | Yes | Yes | 8 | 9 | 2 | 2 | | S:S:M778 | S:S:T781 | 3.01 | 7 | Yes | No | 9 | 9 | 2 | 2 | | S:S:S809 | S:S:W785 | 3.71 | 7 | No | No | 9 | 8 | 1 | 1 | | S:S:W785 | X:X:?1 | 22.97 | 7 | No | Yes | 8 | 0 | 1 | 0 | | S:S:L786 | S:S:V789 | 2.98 | 0 | No | Yes | 6 | 7 | 2 | 1 | | S:S:P790 | S:S:V789 | 3.53 | 0 | No | Yes | 9 | 7 | 2 | 1 | | S:S:F793 | S:S:V789 | 3.93 | 0 | No | Yes | 6 | 7 | 2 | 1 | | S:S:V789 | X:X:?1 | 4.29 | 0 | Yes | Yes | 7 | 0 | 1 | 0 | | S:S:F793 | S:S:Y792 | 7.22 | 0 | No | Yes | 6 | 8 | 2 | 2 | | S:S:M802 | S:S:Y792 | 5.99 | 0 | No | Yes | 8 | 8 | 1 | 2 | | S:S:M802 | X:X:?1 | 8.96 | 0 | No | Yes | 8 | 0 | 1 | 0 | | S:S:S805 | X:X:?1 | 12.11 | 0 | No | Yes | 8 | 0 | 1 | 0 | | S:S:V806 | X:X:?1 | 5.15 | 0 | No | Yes | 8 | 0 | 1 | 0 | | S:S:S809 | X:X:?1 | 9.52 | 7 | No | Yes | 9 | 0 | 1 | 0 | | S:S:A810 | X:X:?1 | 3.63 | 0 | No | Yes | 7 | 0 | 1 | 0 | | S:S:G624 | S:S:S654 | 1.86 | 0 | No | Yes | 8 | 7 | 2 | 1 | | S:S:G624 | S:S:S658 | 1.86 | 0 | No | Yes | 8 | 6 | 2 | 1 | |
| Statistics | Value |
|---|
| Average Number Of Links | 12.00 | | Average Number Of Links With An Hub | 4.00 | | Average Interaction Strength | 7.84 | | Average Nodes In Shell | 30.00 | | Average Hubs In Shell | 10.00 | | Average Links In Shell | 38.00 | | Average Links Mediated by Hubs In Shell | 34.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 8X0D | C | Aminoacid | Metabotropic Glutamate | mGlu5; mGlu5 | Homo Sapiens | Quisqualate | VU0424465 | - | 3.5 | 2024-11-06 | doi.org/10.1038/s41467-024-55439-9 |
|
A 2D representation of the interactions of XQT in 8X0D
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | R:R:A810 | R:R:Y629 | 6.67 | 0 | No | Yes | 7 | 8 | 1 | 2 | | R:R:I651 | R:R:L635 | 2.85 | 4 | No | Yes | 7 | 7 | 2 | 2 | | R:R:L635 | R:R:M802 | 2.83 | 4 | Yes | Yes | 7 | 8 | 2 | 1 | | R:R:I651 | R:R:M802 | 5.83 | 4 | No | Yes | 7 | 8 | 2 | 1 | | R:R:P655 | R:R:S654 | 3.56 | 4 | Yes | Yes | 8 | 7 | 1 | 2 | | R:R:P655 | R:R:Y659 | 4.17 | 4 | Yes | Yes | 8 | 7 | 1 | 1 | | R:R:N747 | R:R:P655 | 8.15 | 0 | No | Yes | 7 | 8 | 2 | 1 | | R:R:P655 | W:W:?1 | 11.35 | 4 | Yes | Yes | 8 | 0 | 1 | 0 | | R:R:S658 | W:W:?1 | 6.92 | 0 | No | Yes | 6 | 0 | 1 | 0 | | R:R:I751 | R:R:Y659 | 3.63 | 4 | No | Yes | 8 | 7 | 2 | 1 | | R:R:W785 | R:R:Y659 | 2.89 | 4 | Yes | Yes | 8 | 7 | 1 | 1 | | R:R:Y659 | W:W:?1 | 6.75 | 4 | Yes | Yes | 7 | 0 | 1 | 0 | | R:R:L744 | R:R:V740 | 2.98 | 0 | No | No | 8 | 8 | 1 | 2 | | R:R:L744 | W:W:?1 | 4.78 | 0 | No | Yes | 8 | 0 | 1 | 0 | | R:R:N747 | R:R:W785 | 4.52 | 0 | No | Yes | 7 | 8 | 2 | 1 | | R:R:I751 | R:R:W785 | 7.05 | 4 | No | Yes | 8 | 8 | 2 | 1 | | R:R:S809 | R:R:T781 | 3.2 | 4 | No | No | 9 | 9 | 1 | 2 | | R:R:S809 | R:R:W785 | 4.94 | 4 | No | Yes | 9 | 8 | 1 | 1 | | R:R:W785 | W:W:?1 | 20.34 | 4 | Yes | Yes | 8 | 0 | 1 | 0 | | R:R:F788 | W:W:?1 | 5.61 | 0 | No | Yes | 9 | 0 | 1 | 0 | | R:R:K798 | R:R:Y792 | 13.14 | 0 | No | Yes | 6 | 8 | 2 | 1 | | R:R:T801 | R:R:Y792 | 6.24 | 0 | No | Yes | 8 | 8 | 2 | 1 | | R:R:M802 | R:R:Y792 | 9.58 | 4 | Yes | Yes | 8 | 8 | 1 | 1 | | R:R:Y792 | W:W:?1 | 5.4 | 4 | Yes | Yes | 8 | 0 | 1 | 0 | | R:R:M802 | R:R:V806 | 3.04 | 4 | Yes | No | 8 | 8 | 1 | 1 | | R:R:M802 | W:W:?1 | 9.77 | 4 | Yes | Yes | 8 | 0 | 1 | 0 | | R:R:S805 | W:W:?1 | 12.98 | 0 | No | Yes | 8 | 0 | 1 | 0 | | R:R:V806 | W:W:?1 | 10.3 | 4 | No | Yes | 8 | 0 | 1 | 0 | | R:R:S809 | W:W:?1 | 8.65 | 4 | No | Yes | 9 | 0 | 1 | 0 | | R:R:A810 | W:W:?1 | 2.72 | 0 | No | Yes | 7 | 0 | 1 | 0 | | R:R:F788 | R:R:I791 | 2.51 | 0 | No | No | 9 | 7 | 1 | 2 | | R:R:F788 | R:R:F804 | 2.14 | 0 | No | No | 9 | 7 | 1 | 2 | | R:R:G745 | R:R:L744 | 1.71 | 0 | No | No | 5 | 8 | 2 | 1 | |
| Statistics | Value |
|---|
| Average Number Of Links | 12.00 | | Average Number Of Links With An Hub | 5.00 | | Average Interaction Strength | 8.80 | | Average Nodes In Shell | 26.00 | | Average Hubs In Shell | 9.00 | | Average Links In Shell | 33.00 | | Average Links Mediated by Hubs In Shell | 28.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of XQT in 8X0D
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | S:S:L627 | S:S:S654 | 4.5 | 3 | Yes | Yes | 5 | 7 | 2 | 1 | | S:S:G628 | S:S:S654 | 3.71 | 0 | No | Yes | 6 | 7 | 2 | 1 | | S:S:I651 | S:S:L635 | 5.71 | 3 | Yes | Yes | 7 | 7 | 2 | 2 | | S:S:L635 | S:S:M802 | 2.83 | 3 | Yes | Yes | 7 | 8 | 2 | 1 | | S:S:I651 | S:S:M802 | 7.29 | 3 | Yes | Yes | 7 | 8 | 2 | 1 | | S:S:P655 | S:S:S654 | 5.34 | 3 | Yes | Yes | 8 | 7 | 1 | 1 | | S:S:S654 | X:X:?1 | 5.19 | 3 | Yes | Yes | 7 | 0 | 1 | 0 | | S:S:P655 | S:S:Y659 | 2.78 | 3 | Yes | Yes | 8 | 7 | 1 | 1 | | S:S:N747 | S:S:P655 | 8.15 | 0 | No | Yes | 7 | 8 | 2 | 1 | | S:S:P655 | X:X:?1 | 13.24 | 3 | Yes | Yes | 8 | 0 | 1 | 0 | | S:S:S658 | X:X:?1 | 7.79 | 0 | No | Yes | 6 | 0 | 1 | 0 | | S:S:I751 | S:S:Y659 | 7.25 | 3 | Yes | Yes | 8 | 7 | 2 | 1 | | S:S:T781 | S:S:Y659 | 7.49 | 3 | Yes | Yes | 9 | 7 | 2 | 1 | | S:S:L813 | S:S:Y659 | 4.69 | 3 | Yes | Yes | 7 | 7 | 2 | 1 | | S:S:Y659 | X:X:?1 | 4.73 | 3 | Yes | Yes | 7 | 0 | 1 | 0 | | S:S:V740 | S:S:Y792 | 3.79 | 0 | No | Yes | 8 | 8 | 2 | 1 | | S:S:L744 | X:X:?1 | 7.18 | 0 | No | Yes | 8 | 0 | 1 | 0 | | S:S:N747 | S:S:W785 | 4.52 | 0 | No | No | 7 | 8 | 2 | 1 | | S:S:I751 | S:S:T781 | 3.04 | 3 | Yes | Yes | 8 | 9 | 2 | 2 | | S:S:I784 | S:S:T781 | 3.04 | 0 | Yes | Yes | 8 | 9 | 2 | 2 | | S:S:S809 | S:S:T781 | 3.2 | 3 | Yes | Yes | 9 | 9 | 1 | 2 | | S:S:L813 | S:S:T781 | 2.95 | 3 | Yes | Yes | 7 | 9 | 2 | 2 | | S:S:F788 | S:S:I784 | 5.02 | 0 | No | Yes | 9 | 8 | 1 | 2 | | S:S:I784 | S:S:L808 | 9.99 | 0 | Yes | No | 8 | 6 | 2 | 2 | | S:S:S809 | S:S:W785 | 3.71 | 3 | Yes | No | 9 | 8 | 1 | 1 | | S:S:W785 | X:X:?1 | 20.34 | 3 | No | Yes | 8 | 0 | 1 | 0 | | S:S:F788 | S:S:I791 | 5.02 | 0 | No | No | 9 | 7 | 1 | 2 | | S:S:F788 | X:X:?1 | 2.81 | 0 | No | Yes | 9 | 0 | 1 | 0 | | S:S:I791 | S:S:T801 | 4.56 | 0 | No | No | 7 | 8 | 2 | 2 | | S:S:F793 | S:S:Y792 | 9.28 | 0 | No | Yes | 6 | 8 | 2 | 1 | | S:S:K798 | S:S:Y792 | 17.91 | 0 | No | Yes | 6 | 8 | 2 | 1 | | S:S:T801 | S:S:Y792 | 3.75 | 0 | No | Yes | 8 | 8 | 2 | 1 | | S:S:M802 | S:S:Y792 | 4.79 | 3 | Yes | Yes | 8 | 8 | 1 | 1 | | S:S:Y792 | X:X:?1 | 5.4 | 3 | Yes | Yes | 8 | 0 | 1 | 0 | | S:S:M802 | S:S:V806 | 3.04 | 3 | Yes | No | 8 | 8 | 1 | 1 | | S:S:M802 | X:X:?1 | 5.7 | 3 | Yes | Yes | 8 | 0 | 1 | 0 | | S:S:S805 | X:X:?1 | 11.25 | 0 | No | Yes | 8 | 0 | 1 | 0 | | S:S:V806 | X:X:?1 | 7.72 | 3 | No | Yes | 8 | 0 | 1 | 0 | | S:S:L808 | S:S:S809 | 3 | 0 | No | Yes | 6 | 9 | 2 | 1 | | S:S:S809 | X:X:?1 | 6.92 | 3 | Yes | Yes | 9 | 0 | 1 | 0 | | S:S:G745 | S:S:L744 | 1.71 | 0 | No | No | 5 | 8 | 2 | 1 | |
| Statistics | Value |
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| Average Number Of Links | 12.00 | | Average Number Of Links With An Hub | 6.00 | | Average Interaction Strength | 8.19 | | Average Nodes In Shell | 29.00 | | Average Hubs In Shell | 14.00 | | Average Links In Shell | 41.00 | | Average Links Mediated by Hubs In Shell | 37.00 |
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Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
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