CodeZ2C
Name4-({2-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(3S)-3-hydroxy-4-[3-(methoxymethyl)phenyl]butyl}cyclopentyl]ethyl}sulfanyl)butanoic acid
Synonyms
Identifier
FormulaC23 H36 O6 S
Molecular Weight440.593
SMILES
PubChem169501697
Formal Charge0
Total Atoms66
Total Chiral Atoms5
Total Bonds67
Total Aromatic Bonds6
Networks2
 missing image

This ligand is also present in the following 2 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8GD9 A Lipid Prostanoid EP4 Homo Sapiens Rivenprost - Gs/Beta1/Gamma2 3.2 2024-01-03 doi.org/10.1073/pnas.2216329120

A 2D representation of the interactions of Z2C in 8GD9
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?1 R:R:T69 7.73 4 Yes No 0 8 0 1
L:L:?1 R:R:S73 7.88 4 Yes Yes 0 8 0 1
L:L:?1 R:R:T76 8.7 4 Yes No 0 8 0 1
L:L:?1 R:R:L99 2.72 4 Yes No 0 8 0 1
L:L:?1 R:R:F102 23.96 4 Yes Yes 0 7 0 1
L:L:?1 R:R:S103 12.8 4 Yes No 0 7 0 1
L:L:?1 R:R:T168 4.83 4 Yes Yes 0 6 0 1
L:L:?1 R:R:W169 8.96 4 Yes Yes 0 5 0 1
L:L:?1 R:R:L312 5.45 4 Yes Yes 0 6 0 1
L:L:?1 R:R:I315 6.55 4 Yes Yes 0 6 0 1
L:L:?1 R:R:R316 12.75 4 Yes No 0 7 0 1
L:L:?1 R:R:S319 20.68 4 Yes No 0 8 0 1
L:L:?1 R:R:P322 9.69 4 Yes Yes 0 9 0 1
R:R:F28 R:R:S73 10.57 0 No Yes 6 8 2 1
R:R:D65 R:R:F102 9.55 0 Yes Yes 9 7 2 1
R:R:F102 R:R:G68 7.53 4 Yes No 7 8 1 2
R:R:L99 R:R:V72 5.96 0 No No 8 7 1 2
R:R:P74 R:R:S73 3.56 0 No Yes 9 8 2 1
R:R:T76 R:R:Y80 2.5 0 No Yes 8 6 1 2
R:R:T79 R:R:Y80 4.99 4 No Yes 7 6 2 2
R:R:T168 R:R:T79 3.14 4 Yes No 6 7 1 2
R:R:T168 R:R:Y80 11.24 4 Yes Yes 6 6 1 2
R:R:F102 R:R:P322 5.78 4 Yes Yes 7 9 1 1
R:R:P166 R:R:Q164 3.16 4 Yes No 6 7 2 2
R:R:Q164 R:R:W169 23 4 No Yes 7 5 2 1
R:R:P166 R:R:T168 8.74 4 Yes Yes 6 6 2 1
R:R:P166 R:R:W169 4.05 4 Yes Yes 6 5 2 1
R:R:L312 R:R:P166 4.93 4 Yes Yes 6 6 1 2
R:R:T168 R:R:W169 6.06 4 Yes Yes 6 5 1 1
R:R:F171 R:R:W169 4.01 4 Yes Yes 6 5 2 1
R:R:L312 R:R:W169 4.56 4 Yes Yes 6 5 1 1
R:R:I315 R:R:W169 8.22 4 Yes Yes 6 5 1 1
R:R:F171 R:R:I315 2.51 4 Yes Yes 6 6 2 1
R:R:I315 R:R:L288 2.85 4 Yes No 6 7 1 2
R:R:L312 R:R:N309 6.87 4 Yes No 6 2 1 2
R:R:L312 R:R:Q313 5.32 4 Yes No 6 3 1 2
R:R:L312 R:R:R316 4.86 4 Yes No 6 7 1 1
R:R:P322 R:R:S319 3.56 4 Yes No 9 8 1 1
R:R:N321 R:R:P322 4.89 0 Yes Yes 9 9 2 1
R:R:I77 R:R:S73 1.55 0 No Yes 6 8 2 1
StatisticsValue
Average Number Of Links13.00
Average Number Of Links With An Hub7.00
Average Interaction Strength10.21
Average Nodes In Shell29.00
Average Hubs In Shell13.00
Average Links In Shell40.00
Average Links Mediated by Hubs In Shell39.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links13.00
Average Number Of Links With An Hub6.50
Average Interaction Strength10.21
Average Nodes In Shell29.00
Average Hubs In Shell11.50
Average Links In Shell39.00
Average Links Mediated by Hubs In Shell37.00

missing image


Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

missing image


Location of the nodes interacting with this ligand

(Click to enlarge 🔍)