CodeZIR
NameRiboprine
Synonyms
  • Riboprine
  • IPA
  • riboprina
Identifier
FormulaC15 H21 N5 O4
Molecular Weight335.358
SMILES
PubChem24405
Formal Charge0
Total Atoms45
Total Chiral Atoms4
Total Bonds47
Total Aromatic Bonds10
Networks2
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This ligand is also present in the following 2 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8YH5 A Nucleotide Adenosine A3A Homo Sapiens Riboprine - Gi1/Beta1/Gamma2 3.66 2024-11-06 doi.org/10.1038/s41467-024-53473-1

A 2D representation of the interactions of ZIR in 8YH5
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:I268 R:R:Y15 13.3 2 Yes No 5 4 1 2
R:R:E19 R:R:H272 17.23 0 Yes Yes 5 7 2 1
R:R:M90 R:R:V65 7.61 0 No No 6 7 1 2
R:R:H272 R:R:V65 4.15 2 Yes No 7 7 1 2
R:R:L68 R:R:M90 8.48 0 No No 5 6 2 1
R:R:F168 R:R:T87 5.19 2 No No 5 4 1 2
L:L:?1 R:R:M90 4.39 2 Yes No 0 6 0 1
R:R:L91 R:R:M172 2.83 2 Yes Yes 4 4 2 2
R:R:L91 R:R:Y176 3.52 2 Yes Yes 4 6 2 2
R:R:L91 R:R:M177 4.24 2 Yes Yes 4 5 2 1
R:R:F168 R:R:M177 4.98 2 No Yes 5 5 1 1
L:L:?1 R:R:F168 31.8 2 Yes No 0 5 0 1
R:R:M174 R:R:R169 7.44 0 No No 3 4 1 2
R:R:M172 R:R:Y176 9.58 2 Yes Yes 4 6 2 2
R:R:M172 R:R:M177 4.33 2 Yes Yes 4 5 2 1
R:R:M174 R:R:Y254 3.59 0 No Yes 3 4 1 2
L:L:?1 R:R:M174 6.15 2 Yes No 0 3 0 1
R:R:M177 R:R:Y176 3.59 2 Yes Yes 5 6 1 2
R:R:M177 R:R:S181 3.07 2 Yes No 5 5 1 2
L:L:?1 R:R:M177 2.64 2 Yes Yes 0 5 0 1
R:R:L246 R:R:N250 4.12 2 Yes No 6 5 1 1
R:R:G267 R:R:L246 5.13 0 No Yes 6 6 2 1
R:R:I268 R:R:L246 5.71 2 Yes Yes 5 6 1 1
L:L:?1 R:R:L246 5.16 2 Yes Yes 0 6 0 1
R:R:I249 R:R:N250 2.83 2 No No 5 5 2 1
R:R:I249 R:R:V259 3.07 2 No Yes 5 4 2 2
L:L:?1 R:R:N250 16.22 2 Yes No 0 5 0 1
R:R:L253 R:R:V259 8.94 0 No Yes 4 4 1 2
L:L:?1 R:R:L253 4.3 2 Yes No 0 4 0 1
L:L:?1 R:R:L264 7.74 2 Yes No 0 4 0 1
R:R:H272 R:R:I268 5.3 2 Yes Yes 7 5 1 1
L:L:?1 R:R:I268 14.19 2 Yes Yes 0 5 0 1
L:L:?1 R:R:H272 10.39 2 Yes Yes 0 7 0 1
L:L:?1 R:R:I72 1.77 2 Yes No 0 5 0 1
StatisticsValue
Average Number Of Links11.00
Average Number Of Links With An Hub4.00
Average Interaction Strength9.52
Average Nodes In Shell26.00
Average Hubs In Shell11.00
Average Links In Shell34.00
Average Links Mediated by Hubs In Shell29.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links10.50
Average Number Of Links With An Hub3.50
Average Interaction Strength9.87
Average Nodes In Shell23.50
Average Hubs In Shell9.00
Average Links In Shell29.00
Average Links Mediated by Hubs In Shell24.50

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)