psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:R554	R:R:T708	6.47	No	No	0	8	4
2	R:R:L556	R:R:T716	2.95	No	No	0	4	7
3	R:R:L556	R:R:V718	4.47	No	No	0	4	7
4	R:R:I715	R:R:V557	4.61	Yes	No	0	4	5
5	R:R:E560	R:R:F558	8.16	No	No	0	6	7
6	R:R:F558	R:R:G623	3.01	No	No	6	7	8
7	R:R:F558	R:R:P624	11.56	No	No	6	7	5
8	R:R:L559	R:R:T566	2.95	No	No	7	8	7
9	R:R:L559	R:R:V622	5.96	No	No	0	8	7
10	R:R:I790	R:R:L559	7.14	Yes	No	7	8	8
11	R:R:P619	R:R:W561	4.05	No	No	0	6	5
12	R:R:V622	R:R:W561	9.81	No	No	0	7	5
13	R:R:E563	R:R:T566	9.88	No	No	0	8	7
14	R:R:I790	R:R:P565	3.39	Yes	No	0	8	6
15	R:R:I790	R:R:T566	3.04	Yes	No	7	8	7
16	R:R:I790	R:R:V569	3.07	Yes	No	0	8	8
17	R:R:L793	R:R:V569	2.98	Yes	No	0	8	8
18	R:R:L794	R:R:V569	2.98	No	No	0	7	8
19	R:R:L572	R:R:V797	4.47	No	No	0	3	9
20	R:R:L572	R:R:L801	4.15	No	No	0	3	6
21	R:R:A573	R:R:V797	3.39	No	No	0	7	9
22	R:R:G576	R:R:L575	3.42	No	No	0	6	2
23	R:R:G576	R:R:Y615	7.24	No	Yes	0	6	8
24	R:R:F577	R:R:L612	9.74	No	No	0	6	4
25	R:R:F577	R:R:Y615	3.09	No	Yes	0	6	8
26	R:R:L805	R:R:S579	3	No	No	0	2	4
27	R:R:L612	R:R:T580	5.9	No	No	0	4	8
28	R:R:T580	R:R:Y615	4.99	No	Yes	8	8	8
29	R:R:S804	R:R:T580	6.4	No	No	8	8	8
30	R:R:I583	R:R:L608	2.85	No	No	0	7	9
31	R:R:C812	R:R:I583	8.18	No	No	0	7	7
32	R:R:F605	R:R:L584	3.65	Yes	No	0	6	4
33	R:R:C812	R:R:I586	4.91	No	No	0	7	5
34	R:R:F587	R:R:V596	9.18	Yes	No	0	9	9
35	R:R:F587	R:R:F605	3.22	Yes	Yes	0	9	6
36	R:R:F587	R:R:F808	3.22	Yes	Yes	3	9	9
37	R:R:F587	R:R:K811	3.72	Yes	No	0	9	9
38	R:R:C812	R:R:F587	4.19	No	Yes	0	7	9
39	R:R:R589	R:R:W588	3	No	No	0	4	5
40	R:R:F605	R:R:W588	7.02	Yes	No	0	6	5
41	R:R:H590	R:R:I815	6.63	No	No	0	5	8
42	R:R:F591	R:R:P602	2.89	No	No	0	5	6
43	R:R:F591	R:R:F605	3.22	No	Yes	0	5	6
44	R:R:P594	R:R:T593	5.25	Yes	No	9	8	9
45	R:R:N822	R:R:T593	10.24	No	No	9	9	9
46	R:R:N822	R:R:P594	6.52	No	Yes	9	9	8
47	R:R:F827	R:R:P594	7.22	Yes	Yes	0	7	8
48	R:R:I595	R:R:Y756	10.88	Yes	No	0	7	9
49	R:R:I595	R:R:I815	8.83	Yes	No	0	7	8
50	R:R:I595	R:R:N822	14.16	Yes	No	0	7	9
51	R:R:N755	R:R:S598	2.98	Yes	No	0	8	9
52	R:R:A599	R:R:K811	3.21	No	No	0	9	9
53	R:R:G601	R:R:P602	4.06	No	No	0	8	6
54	R:R:M603	R:R:Y679	5.99	No	No	0	8	5
55	R:R:L606	R:R:L610	4.15	No	No	0	6	8
56	R:R:C644	R:R:M607	6.48	No	No	0	7	8
57	R:R:C647	R:R:M607	9.73	No	No	0	7	8
58	R:R:F808	R:R:L608	9.74	Yes	No	0	9	9
59	R:R:I643	R:R:L610	2.85	No	No	0	7	8
60	R:R:C644	R:R:L611	4.76	No	No	0	7	9
61	R:R:I803	R:R:L611	2.85	No	No	0	8	9
62	R:R:A614	R:R:L800	4.73	No	No	0	6	8
63	R:R:L800	R:R:Y615	8.21	No	Yes	0	8	8
64	R:R:L801	R:R:Y615	5.86	No	Yes	0	6	8
65	R:R:S804	R:R:Y615	6.36	No	Yes	8	8	8
66	R:R:F637	R:R:V617	10.49	No	No	0	8	6
67	R:R:L793	R:R:V617	2.98	Yes	No	0	8	6
68	R:R:P619	R:R:V618	3.53	No	No	0	6	7
69	R:R:L793	R:R:V618	4.47	Yes	No	0	8	7
70	R:R:C632	R:R:V620	3.42	No	No	0	6	6
71	R:R:F637	R:R:V620	5.24	No	No	0	8	6
72	R:R:R633	R:R:Y621	17.49	No	No	0	8	8
73	R:R:D792	R:R:Y621	5.75	No	No	0	9	8
74	R:R:L793	R:R:Y621	18.76	Yes	No	0	8	8
75	R:R:G623	R:R:V622	3.68	No	No	0	8	7
76	R:R:G623	R:R:P624	4.06	No	No	6	8	5
77	R:R:P625	R:R:P704	7.79	No	No	0	9	6
78	R:R:P625	R:R:V718	3.53	No	No	0	9	7
79	R:R:C630	R:R:P704	3.77	No	No	0	9	6
80	R:R:C630	R:R:C720	5.46	No	No	0	9	9
81	R:R:L631	R:R:L702	4.15	No	Yes	0	5	8
82	R:R:C720	R:R:R633	11.14	No	No	0	9	8
83	R:R:M697	R:R:Q634	8.16	Yes	No	0	7	8
84	R:R:A635	R:R:M697	3.22	No	Yes	0	5	7
85	R:R:I643	R:R:L639	4.28	No	No	0	7	7
86	R:R:K689	R:R:L639	2.82	Yes	No	0	9	7
87	R:R:L639	R:R:M690	4.24	No	No	0	7	4
88	R:R:F641	R:R:I645	8.79	No	No	0	8	7
89	R:R:F641	R:R:Y769	6.19	No	Yes	0	8	8
90	R:R:K689	R:R:T642	15.02	Yes	No	10	9	8
91	R:R:D735	R:R:T642	10.12	No	No	10	8	8
92	R:R:I643	R:R:T686	4.56	No	No	0	7	7
93	R:R:I645	R:R:I803	2.94	No	No	0	7	8
94	R:R:M682	R:R:S646	3.07	No	No	0	7	9
95	R:R:I685	R:R:S646	3.1	No	No	0	5	9
96	R:R:C647	R:R:M682	3.24	No	No	0	7	7
97	R:R:I648	R:R:I762	2.94	No	Yes	3	7	9
98	R:R:I648	R:R:I803	2.94	No	No	0	7	8
99	R:R:I648	R:R:Y807	3.63	No	Yes	3	7	8
100	R:R:N755	R:R:R651	3.62	Yes	No	3	8	9
101	R:R:E758	R:R:R651	12.79	Yes	No	3	9	9
102	R:R:R651	R:R:Y807	4.12	No	Yes	3	9	8
103	R:R:G742	R:R:S652	3.71	No	No	0	9	9
104	R:R:I762	R:R:S652	4.64	Yes	No	0	9	9
105	R:R:C657	R:R:F653	8.38	No	Yes	2	6	7
106	R:R:F653	R:R:Y669	4.13	Yes	Yes	2	7	7
107	R:R:F653	R:R:W672	3.01	Yes	Yes	2	7	6
108	R:R:F653	R:R:F745	10.72	Yes	Yes	2	7	7
109	R:R:Q654	R:R:W672	5.48	No	Yes	2	8	6
110	R:R:P678	R:R:Q654	3.16	Yes	No	2	8	8
111	R:R:I655	R:R:T754	3.04	No	No	0	9	7
112	R:R:E758	R:R:I655	4.1	Yes	No	0	9	9
113	R:R:F745	R:R:V656	3.93	Yes	No	2	7	7
114	R:R:G749	R:R:V656	3.68	No	No	2	9	7
115	R:R:L752	R:R:V656	2.98	No	No	2	8	7
116	R:R:C657	R:R:M661	6.48	No	Yes	0	6	7
117	R:R:C657	R:R:F745	4.19	No	Yes	2	6	7
118	R:R:A658	R:R:Y669	4	No	Yes	0	8	7
119	R:R:F665	R:R:M661	4.98	No	Yes	0	5	7
120	R:R:M661	R:R:Y669	10.78	Yes	Yes	0	7	7
121	R:R:F665	R:R:R664	18.17	No	No	0	5	7
122	R:R:W672	R:R:Y669	5.79	Yes	Yes	2	6	7
123	R:R:V673	R:R:Y669	5.05	No	Yes	0	6	7
124	R:R:R674	R:R:Y671	5.14	No	No	11	7	5
125	R:R:Y671	R:R:Y675	6.95	No	No	11	5	6
126	R:R:G677	R:R:W672	8.44	No	Yes	2	8	6
127	R:R:P678	R:R:W672	10.81	Yes	Yes	2	8	6
128	R:R:S681	R:R:W672	6.18	No	Yes	0	7	6
129	R:R:R674	R:R:Y675	13.38	No	No	11	7	6
130	R:R:Q676	R:R:Y679	5.64	No	No	0	3	5
131	R:R:G677	R:R:P678	4.06	No	Yes	2	8	8
132	R:R:G677	R:R:V680	3.68	No	No	0	8	4
133	R:R:M682	R:R:Y679	3.59	No	No	0	7	5
134	R:R:F684	R:R:I685	3.77	No	No	0	3	5
135	R:R:I685	R:R:L738	7.14	No	No	0	5	9
136	R:R:L688	R:R:L734	5.54	No	No	0	6	8
137	R:R:K689	R:R:V693	4.55	Yes	No	0	9	7
138	R:R:K689	R:R:N731	5.6	Yes	No	0	9	7
139	R:R:K689	R:R:L734	4.23	Yes	No	0	9	8
140	R:R:D735	R:R:K689	5.53	No	Yes	10	8	9
141	R:R:M690	R:R:V691	3.04	No	No	0	4	3
142	R:R:I695	R:R:V691	3.07	No	No	0	4	3
143	R:R:G696	R:R:I695	3.53	No	No	0	7	4
144	R:R:L702	R:R:M697	4.24	Yes	Yes	0	8	7
145	R:R:P722	R:R:T700	5.25	No	No	0	6	6
146	R:R:P704	R:R:S703	3.56	No	No	0	6	4
147	R:R:P722	R:R:T705	8.74	No	No	0	6	3
148	R:R:T706	R:R:T716	3.14	No	No	0	3	7
149	R:R:T706	R:R:V718	4.76	No	No	0	3	7
150	R:R:I717	R:R:R707	10.02	No	No	0	6	6
151	R:R:D709	R:R:P710	11.27	Yes	No	0	3	4
152	R:R:D709	R:R:D711	7.98	Yes	No	0	3	5
153	R:R:D709	R:R:I715	8.4	Yes	Yes	0	3	4
154	R:R:D709	R:R:I717	4.2	Yes	No	0	3	6
155	R:R:D712	R:R:P713	3.22	No	No	0	4	4
156	R:R:I717	R:R:V786	4.61	No	No	0	6	8
157	R:R:S719	R:R:T789	3.2	No	No	0	5	7
158	R:R:N721	R:R:S727	7.45	No	No	0	6	6
159	R:R:M780	R:R:Y724	8.38	No	Yes	0	8	8
160	R:R:S784	R:R:Y724	5.09	No	Yes	0	6	8
161	R:R:V788	R:R:Y724	5.05	No	Yes	0	7	8
162	R:R:R725	R:R:S781	9.22	No	No	0	2	5
163	R:R:F730	R:R:N726	8.46	No	No	0	4	2
164	R:R:L728	R:R:M780	8.48	No	No	0	7	8
165	R:R:D792	R:R:L728	4.07	No	No	0	9	7
166	R:R:F730	R:R:L729	8.53	No	No	0	4	5
167	R:R:N731	R:R:T732	2.92	No	No	0	7	7
168	R:R:D735	R:R:Y769	4.6	No	Yes	0	8	8
169	R:R:L736	R:R:S773	3	No	No	0	6	9
170	R:R:S739	R:R:Y769	5.09	No	Yes	0	8	8
171	R:R:F743	R:R:Y747	5.16	No	No	0	8	8
172	R:R:F743	R:R:T763	3.89	No	No	0	8	9
173	R:R:F745	R:R:M748	3.73	Yes	No	0	7	7
174	R:R:A746	R:R:I762	3.25	No	Yes	0	9	9
175	R:R:A746	R:R:T763	3.36	No	No	0	9	9
176	R:R:K750	R:R:Y747	7.17	No	No	0	9	8
177	R:R:G749	R:R:L752	3.42	No	No	2	9	8
178	R:R:K750	S:S:L755	5.64	No	Yes	0	9	8
179	R:R:K750	S:S:Q757	5.42	No	No	0	9	9
180	R:R:N757	R:R:P753	4.89	No	No	0	9	9
181	R:R:N755	R:R:T754	4.39	Yes	No	0	8	7
182	R:R:E758	R:R:N755	3.94	Yes	Yes	3	9	8
183	R:R:F827	R:R:Y756	6.19	Yes	No	0	7	9
184	R:R:M830	R:R:Y756	3.59	No	No	0	4	9
185	R:R:E758	R:R:Y807	7.86	Yes	Yes	3	9	8
186	R:R:E758	R:R:K811	5.4	Yes	No	0	9	9
187	R:R:K760	S:S:E668	6.75	No	No	0	9	6
188	R:R:K760	S:S:L755	5.64	No	Yes	0	9	8
189	R:R:F761	R:R:P810	17.34	No	No	0	5	9
190	R:R:I762	R:R:Y807	3.63	Yes	Yes	3	9	8
191	R:R:T763	S:S:L755	5.9	No	Yes	0	9	8
192	R:R:M766	R:R:S765	3.07	No	No	0	9	9
193	R:R:F768	S:S:F747	4.29	No	Yes	0	7	3
194	R:R:S773	R:R:Y769	8.9	No	Yes	0	9	8
195	R:R:N799	R:R:Y769	8.14	No	Yes	0	9	8
196	R:R:F770	R:R:V774	3.93	No	No	0	6	6
197	R:R:T771	S:S:F747	5.19	No	Yes	0	8	3
198	R:R:S772	R:R:V795	3.23	No	No	12	9	8
199	R:R:N799	R:R:S772	5.96	No	No	12	9	9
200	R:R:V774	S:S:V781	3.21	No	No	13	6	6
201	R:R:L776	R:R:M780	2.83	No	No	0	9	8
202	R:R:L776	R:R:V795	7.45	No	No	0	9	8
203	R:R:T778	S:S:V784	4.76	No	No	0	8	7
204	R:R:F779	R:R:Y783	12.38	No	Yes	0	7	8
205	R:R:F779	R:R:V791	13.11	No	No	0	7	7
206	R:R:G785	R:R:Y783	7.24	No	Yes	0	7	8
207	R:R:L787	R:R:Y783	10.55	No	Yes	0	5	8
208	R:R:D792	R:R:T796	4.34	No	No	0	9	8
209	R:R:L794	R:R:L798	4.15	No	No	0	7	7
210	R:R:N799	R:R:V795	4.43	No	No	12	9	8
211	R:R:F808	R:R:Y807	9.28	Yes	Yes	3	9	8
212	R:R:G809	R:R:P810	4.06	No	No	0	3	9
213	R:R:F817	R:R:Y813	5.16	No	No	0	5	8
214	R:R:Y813	R:R:Y818	5.96	No	No	0	8	6
215	R:R:F817	R:R:L816	9.74	No	No	0	5	6
216	R:R:R821	R:R:Y818	3.09	No	No	0	5	6
217	R:R:E820	R:R:T823	4.23	No	No	0	7	7
218	R:R:R821	R:R:Y826	19.55	No	No	0	5	5
219	R:R:P824	R:R:T823	3.5	No	No	0	6	7
220	R:R:M830	R:R:Y826	4.79	No	No	0	4	5
221	R:R:F827	R:R:I831	7.54	Yes	No	0	7	7
222	S:S:R562	S:S:V723	3.92	No	No	0	8	7
223	S:S:F566	S:S:P564	2.89	No	No	0	7	4
224	S:S:K565	S:S:L719	4.23	No	Yes	14	5	4
225	S:S:E722	S:S:K565	17.55	No	No	14	5	5
226	S:S:F566	S:S:R632	11.76	No	No	5	7	4
227	S:S:F566	S:S:P633	2.89	No	Yes	5	7	9
228	S:S:L567	S:S:V574	5.96	Yes	No	15	9	7
229	S:S:L567	S:S:P630	3.28	Yes	Yes	15	9	7
230	S:S:L567	S:S:P796	3.28	Yes	No	0	9	8
231	S:S:A568	S:S:E571	3.02	No	Yes	0	7	7
232	S:S:L578	S:S:W569	3.42	No	No	0	4	5
233	S:S:P630	S:S:W569	8.11	Yes	No	0	7	5
234	S:S:G631	S:S:W569	4.22	No	No	0	8	5
235	S:S:G570	S:S:L575	5.13	No	No	0	4	5
236	S:S:E571	S:S:P572	4.72	Yes	No	0	7	4
237	S:S:E571	S:S:V573	2.85	Yes	No	0	7	7
238	S:S:E571	S:S:Y794	7.86	Yes	No	0	7	4
239	S:S:L578	S:S:V574	2.98	No	No	0	4	7
240	S:S:P630	S:S:V574	3.53	Yes	No	15	7	7
241	S:S:L577	S:S:M800	5.65	No	Yes	0	8	7
242	S:S:L580	S:S:V584	2.98	No	No	0	3	6
243	S:S:L580	S:S:L804	6.92	No	No	0	3	8
244	S:S:L581	S:S:L804	4.15	No	No	0	7	8
245	S:S:C623	S:S:V584	3.42	No	No	0	8	6
246	S:S:L808	S:S:V584	2.98	No	No	0	6	6
247	S:S:L585	S:S:L589	4.15	Yes	No	0	7	4
248	S:S:L585	S:S:L624	4.15	Yes	No	0	7	6
249	S:S:L587	S:S:L811	4.15	No	Yes	0	4	8
250	S:S:A588	S:S:L811	3.15	No	Yes	0	7	8
251	S:S:A591	S:S:L616	3.15	No	No	0	6	9
252	S:S:L592	S:S:V596	2.98	Yes	No	0	5	4
253	S:S:C613	S:S:L592	3.17	No	Yes	0	7	5
254	S:S:I617	S:S:L592	2.85	No	Yes	0	4	5
255	S:S:C819	S:S:L594	3.17	No	No	0	7	6
256	S:S:L594	S:S:L823	5.54	No	No	0	6	5
257	S:S:F612	S:S:S595	6.61	Yes	No	0	8	9
258	S:S:C613	S:S:S595	3.44	No	No	0	7	9
259	S:S:H597	S:S:H598	8.36	No	No	0	4	5
260	S:S:H598	S:S:L822	10.29	No	No	0	5	9
261	S:S:D600	S:S:W599	5.58	No	No	0	4	5
262	S:S:C613	S:S:W599	3.92	No	No	0	7	5
263	S:S:P602	S:S:S601	3.56	No	No	16	9	9
264	S:S:S601	S:S:V604	3.23	No	No	0	9	9
265	S:S:N829	S:S:S601	8.94	No	No	16	9	9
266	S:S:N829	S:S:P602	8.15	No	No	16	9	9
267	S:S:P602	S:S:Q831	7.9	No	No	0	9	6
268	S:S:K818	S:S:L603	7.05	Yes	Yes	0	9	8
269	S:S:L603	S:S:V821	2.98	Yes	No	0	8	8
270	S:S:L603	S:S:L822	5.54	Yes	No	0	8	9
271	S:S:L603	S:S:N829	4.12	Yes	No	0	8	9
272	S:S:F834	S:S:L603	14.61	No	Yes	0	5	8
273	S:S:A606	S:S:L835	3.15	No	No	0	9	7
274	S:S:F612	S:S:S607	3.96	Yes	No	4	8	9
275	S:S:K818	S:S:S607	6.12	Yes	No	4	9	9
276	S:S:G608	S:S:Q611	3.29	No	No	0	9	7
277	S:S:Q611	S:S:T655	2.83	No	No	0	7	8
278	S:S:Q611	S:S:W687	15.33	No	No	0	7	4
279	S:S:F612	S:S:H815	9.05	Yes	Yes	0	8	9
280	S:S:F612	S:S:K818	3.72	Yes	Yes	4	8	9
281	S:S:C618	S:S:F614	8.38	No	No	0	8	5
282	S:S:F614	S:S:W687	7.02	No	No	0	5	4
283	S:S:H815	S:S:L616	11.57	Yes	No	0	9	9
284	S:S:C652	S:S:L619	3.17	No	No	0	7	9
285	S:S:A807	S:S:L619	3.15	No	No	0	8	9
286	S:S:L619	S:S:L811	4.15	No	Yes	0	9	8
287	S:S:L621	S:S:P648	3.28	No	No	0	5	7
288	S:S:F622	S:S:L649	14.61	No	No	0	6	8
289	S:S:F622	S:S:I803	8.79	No	No	0	6	9
290	S:S:A645	S:S:S625	3.42	No	No	0	8	8
291	S:S:M800	S:S:V626	3.04	Yes	No	0	7	7
292	S:S:I803	S:S:V626	4.61	No	No	0	9	7
293	S:S:L804	S:S:V626	4.47	No	No	0	8	7
294	S:S:L628	S:S:M644	2.83	No	No	0	6	5
295	S:S:F629	S:S:Q641	16.4	No	No	0	9	8
296	S:S:F629	S:S:Q799	12.88	No	No	0	9	8
297	S:S:F629	S:S:M800	4.98	No	Yes	0	9	7
298	S:S:M800	S:S:P630	8.39	Yes	Yes	0	7	7
299	S:S:P633	S:S:R632	4.32	Yes	No	5	9	4
300	S:S:E725	S:S:R632	11.63	No	No	5	7	4
301	S:S:P633	S:S:V712	3.53	Yes	No	0	9	5
302	S:S:E725	S:S:P633	4.72	No	Yes	5	7	9
303	S:S:S634	S:S:S637	4.89	No	No	0	5	6
304	S:S:C638	S:S:V712	3.42	No	No	0	9	5
305	S:S:C638	S:S:C727	7.28	No	No	0	9	9
306	S:S:L639	S:S:P710	3.28	No	No	0	6	8
307	S:S:C727	S:S:Q641	9.16	No	No	0	9	8
308	S:S:P643	S:S:Q642	3.16	No	No	0	6	8
309	S:S:L735	S:S:Q642	5.32	No	No	0	8	8
310	S:S:Q642	S:S:Q799	5.12	No	No	0	8	8
311	S:S:L705	S:S:P643	3.28	No	No	0	7	6
312	S:S:A645	S:S:I803	3.25	No	No	0	8	9
313	S:S:H646	S:S:H739	15.53	No	Yes	0	5	7
314	S:S:H646	S:S:N742	3.83	No	Yes	0	5	8
315	S:S:L647	S:S:P648	4.93	No	No	0	7	7
316	S:S:E697	S:S:L647	3.98	Yes	No	0	9	7
317	S:S:L649	S:S:L653	6.92	No	Yes	1	8	7
318	S:S:L649	S:S:N742	15.1	No	Yes	1	8	8
319	S:S:E697	S:S:T650	12.7	Yes	No	0	9	8
320	S:S:N742	S:S:T650	8.77	Yes	No	0	8	8
321	S:S:L653	S:S:N742	6.87	Yes	Yes	1	7	8
322	S:S:L653	S:S:M773	2.83	Yes	No	0	7	9
323	S:S:L653	S:S:Y776	3.52	Yes	Yes	1	7	8
324	S:S:S654	S:S:V690	9.7	No	No	0	9	7
325	S:S:L656	S:S:L769	4.15	No	Yes	4	7	9
326	S:S:F814	S:S:L656	6.09	Yes	No	4	9	7
327	S:S:F657	S:S:L745	4.87	No	No	0	8	9
328	S:S:F657	S:S:L748	3.65	No	No	0	8	4
329	S:S:L658	S:S:V689	4.47	No	No	0	7	6
330	S:S:Q659	S:S:R765	5.84	No	Yes	0	9	9
331	S:S:L769	S:S:Q659	3.99	Yes	No	0	9	9
332	S:S:A660	S:S:C749	3.61	No	No	0	9	9
333	S:S:A661	S:S:L681	3.15	No	No	0	6	5
334	S:S:E662	S:S:R682	10.47	No	No	0	8	7
335	S:S:E662	S:S:R765	8.14	No	Yes	0	8	9
336	S:S:R765	S:S:T663	6.47	Yes	No	0	9	9
337	S:S:E668	S:S:F664	5.83	No	No	0	6	6
338	S:S:F664	S:S:G752	3.01	No	No	0	6	7
339	S:S:L677	S:S:V665	4.47	No	No	0	5	7
340	S:S:C678	S:S:E666	4.56	No	No	0	7	8
341	S:S:E668	S:S:S667	4.31	No	No	0	6	9
342	S:S:S667	S:S:V756	4.85	No	No	0	9	8
343	S:S:L669	S:S:P670	4.93	No	No	0	7	8
344	S:S:P670	S:S:W673	4.05	No	No	0	8	6
345	S:S:S672	S:S:W673	4.94	No	No	0	6	6
346	S:S:W673	S:S:W676	4.69	No	No	0	6	5
347	S:S:L677	S:S:W676	3.42	No	No	0	5	5
348	S:S:W676	S:S:Y680	2.89	No	No	0	5	6
349	S:S:C678	S:S:R682	5.57	No	No	0	7	7
350	S:S:S679	S:S:Y680	5.09	No	No	0	6	6
351	S:S:W685	S:S:Y680	5.79	No	No	0	7	6
352	S:S:F695	S:S:L691	9.74	No	No	0	4	3
353	S:S:C701	S:S:E697	6.08	No	Yes	0	7	9
354	S:S:E697	S:S:T741	4.23	Yes	Yes	0	9	8
355	S:S:L700	S:S:L737	5.54	No	No	0	7	3
356	S:S:L700	S:S:T741	2.95	No	Yes	0	7	8
357	S:S:L737	S:S:W703	7.97	No	No	0	3	4
358	S:S:L705	S:S:Y704	3.52	No	Yes	0	7	7
359	S:S:P710	S:S:Y704	6.95	No	Yes	0	8	7
360	S:S:L737	S:S:Y704	3.52	No	Yes	0	3	7
361	S:S:V738	S:S:Y704	5.05	No	Yes	0	7	7
362	S:S:A707	S:S:F708	5.55	No	No	0	4	5
363	S:S:F708	S:S:S734	10.57	No	No	0	5	6
364	S:S:P709	S:S:R730	4.32	No	No	0	8	6
365	S:S:E711	S:S:R730	8.14	No	No	0	5	6
366	S:S:H726	S:S:V713	6.92	No	No	17	6	3
367	S:S:H728	S:S:V713	6.92	No	No	17	6	3
368	S:S:T714	S:S:W716	6.06	No	No	0	3	5
369	S:S:E725	S:S:T714	2.82	No	No	0	7	3
370	S:S:D715	S:S:V718	13.15	No	No	0	7	6
371	S:S:V723	S:S:W716	9.81	No	No	0	7	5
372	S:S:L724	S:S:V718	2.98	Yes	No	0	6	6
373	S:S:L719	S:S:P720	3.28	Yes	No	0	4	3
374	S:S:E722	S:S:L719	3.98	No	Yes	14	5	4
375	S:S:L719	S:S:L724	4.15	Yes	Yes	0	4	6
376	S:S:H726	S:S:L724	7.71	No	Yes	0	6	6
377	S:S:L724	S:S:V792	2.98	Yes	No	0	6	7
378	S:S:H726	S:S:H728	8.36	No	No	17	6	6
379	S:S:V729	S:S:W732	4.9	No	No	0	6	3
380	S:S:S731	S:S:S734	4.89	No	No	0	9	6
381	S:S:L787	S:S:W732	6.83	Yes	No	1	8	3
382	S:S:Q795	S:S:W732	4.38	No	No	1	6	3
383	S:S:H739	S:S:L735	6.43	Yes	No	0	7	8
384	S:S:G736	S:S:H739	3.18	No	Yes	0	5	7
385	S:S:H739	S:S:W780	5.29	Yes	Yes	0	7	9
386	S:S:A746	S:S:Y776	5.34	No	Yes	1	8	8
387	S:S:A746	S:S:F777	4.16	No	No	1	8	7
388	S:S:F747	S:S:L751	12.18	Yes	No	0	3	5
389	S:S:F747	S:S:F777	3.22	Yes	No	0	3	7
390	S:S:C749	S:S:L769	3.17	No	Yes	0	9	9
391	S:S:C749	S:S:M773	6.48	No	No	0	9	9
392	S:S:F750	S:S:F754	16.08	No	Yes	0	8	9
393	S:S:F750	S:S:M773	3.73	No	No	0	8	9
394	S:S:L769	S:S:T753	5.9	Yes	No	0	9	9
395	S:S:T753	S:S:T770	4.71	No	No	0	9	9
396	S:S:F754	S:S:L755	7.31	Yes	Yes	0	9	8
397	S:S:F754	S:S:T770	3.89	Yes	No	0	9	9
398	S:S:A766	S:S:V756	5.09	No	No	0	9	8
399	S:S:N764	S:S:S758	5.96	No	No	0	9	8
400	S:S:R765	S:S:Y763	3.09	Yes	Yes	0	9	9
401	S:S:K818	S:S:Y763	3.58	Yes	Yes	4	9	9
402	S:S:F833	S:S:Y763	5.16	No	Yes	4	4	9
403	S:S:F834	S:S:Y763	17.54	No	Yes	4	5	9
404	S:S:F771	S:S:R767	6.41	No	No	0	9	9
405	S:S:F814	S:S:L769	8.53	Yes	Yes	4	9	9
406	S:S:A772	S:S:T813	3.36	No	No	0	9	6
407	S:S:I778	S:S:L774	4.28	No	No	0	8	8
408	S:S:F777	S:S:Y776	6.19	No	Yes	1	7	8
409	S:S:W780	S:S:Y776	16.4	Yes	Yes	1	9	8
410	S:S:C806	S:S:Y776	4.03	No	Yes	1	9	8
411	S:S:T779	S:S:V805	4.76	No	No	0	8	7
412	S:S:C806	S:S:T779	3.38	No	No	0	9	8
413	S:S:F783	S:S:W780	10.02	No	Yes	1	9	9
414	S:S:A802	S:S:W780	3.89	No	Yes	1	8	9
415	S:S:C806	S:S:W780	9.14	No	Yes	1	9	9
416	S:S:L786	S:S:S782	3	No	No	0	7	7
417	S:S:F783	S:S:L787	8.53	No	Yes	1	9	8
418	S:S:A802	S:S:F783	5.55	No	No	1	8	9
419	S:S:P785	S:S:V784	3.53	No	No	0	9	7
420	S:S:L787	S:S:Q795	5.32	Yes	No	1	8	6
421	S:S:L787	S:S:V798	4.47	Yes	No	0	8	8
422	S:S:Q795	S:S:V790	2.87	No	No	0	6	7
423	S:S:V790	S:S:V798	4.81	No	No	0	7	8
424	S:S:L808	S:S:V812	2.98	No	No	0	6	2
425	S:S:H815	S:S:L811	3.86	Yes	Yes	0	9	8
426	S:S:L816	S:S:V812	2.98	No	No	0	3	2
427	S:S:F814	S:S:H815	7.92	Yes	Yes	0	9	9
428	S:S:F814	S:S:K818	8.69	Yes	Yes	4	9	9
429	S:S:L816	S:S:P817	3.28	No	No	0	3	9
430	S:S:W824	S:S:Y820	13.5	No	No	0	4	8
431	S:S:L825	S:S:Y820	5.86	No	No	0	6	8
432	S:S:L825	S:S:L828	5.54	No	No	0	6	4
433	S:S:E832	S:S:T830	2.82	No	No	0	6	8
434	S:S:L835	S:S:Q831	3.99	No	No	0	7	6
435	S:S:F833	S:S:F834	8.57	No	No	4	4	5
436	R:R:D712	R:R:I715	2.8	No	Yes	0	4	4
437	R:R:M830	R:R:N757	2.8	No	No	0	4	9
438	R:R:C604	R:R:F587	2.79	No	Yes	3	9	9
439	R:R:C604	R:R:F808	2.79	No	Yes	3	9	9
440	R:R:L698	R:R:L702	2.77	No	Yes	0	3	8
441	R:R:L801	R:R:L805	2.77	No	No	0	6	2
442	S:S:L581	S:S:L627	2.77	No	No	0	7	7
443	R:R:I715	R:R:Q555	2.74	Yes	No	0	4	3
444	R:R:H590	R:R:I586	2.65	No	No	0	5	5
445	S:S:E571	S:S:L567	2.65	Yes	Yes	0	7	9
446	S:S:E662	S:S:L681	2.65	No	No	0	8	5
447	S:S:H815	S:S:I810	2.65	Yes	No	0	9	8
448	R:R:F745	R:R:S652	2.64	Yes	No	0	7	9
449	R:R:F770	R:R:S739	2.64	No	No	0	6	8
450	R:R:F637	R:R:V613	2.62	No	No	0	8	6
451	R:R:F745	R:R:V741	2.62	Yes	No	0	7	4
452	S:S:F657	S:S:V689	2.62	No	No	0	8	6
453	R:R:F743	R:R:T767	2.59	No	No	0	8	8
454	R:R:T767	S:S:F754	2.59	No	Yes	0	8	9
455	S:S:A707	S:S:W703	2.59	No	No	0	4	4
456	S:S:F771	S:S:T770	2.59	No	No	0	9	9
457	S:S:H598	S:S:L594	2.57	No	No	0	5	6
458	S:S:E832	S:S:Q831	2.55	No	No	0	6	6
459	R:R:S765	R:R:Y807	2.54	No	Yes	0	9	8
460	R:R:S829	R:R:Y826	2.54	No	No	0	5	5
461	R:R:V788	R:R:Y783	2.52	No	Yes	0	7	8
462	R:R:Y783	S:S:V733	2.52	Yes	No	0	8	3
463	S:S:S610	S:S:W599	2.47	No	No	0	5	5
464	S:S:S610	S:S:W687	2.47	No	No	0	5	4
465	R:R:F641	R:R:L800	2.44	No	No	0	8	8
466	R:R:L764	S:S:F754	2.44	No	Yes	0	9	9
467	S:S:F833	S:S:L828	2.44	No	No	0	4	4
468	R:R:N721	R:R:R633	2.41	No	No	0	6	8
469	S:S:N764	S:S:R767	2.41	No	No	0	9	9
470	R:R:G600	R:R:G601	2.11	No	No	0	9	8
471	S:S:G608	S:S:G609	2.11	No	No	0	9	8
472	R:R:R725	R:R:Y724	2.06	No	Yes	0	2	8
473	R:R:G785	R:R:P710	2.03	No	No	0	7	4
474	S:S:C618	S:S:G615	1.96	No	No	0	8	8
475	S:S:C618	S:S:G651	1.96	No	No	0	8	7
476	R:R:P594	R:R:P824	1.95	Yes	No	0	8	6
477	R:R:A759	R:R:G749	1.95	No	No	0	9	9
478	S:S:P709	S:S:P710	1.95	No	No	0	8	8
479	S:S:A775	S:S:G809	1.95	No	No	0	8	7
480	R:R:A564	R:R:P565	1.87	No	No	0	4	6
481	S:S:G651	S:S:S654	1.86	No	No	0	7	9
482	S:S:G651	S:S:T694	1.82	No	No	0	7	7
483	S:S:G809	S:S:T813	1.82	No	No	0	7	6
484	R:R:P678	R:R:V650	1.77	Yes	No	0	8	8
485	R:R:G809	R:R:I583	1.76	No	No	0	3	7
486	R:R:P625	R:R:T629	1.75	No	No	0	9	6
487	R:R:P713	R:R:T708	1.75	No	No	0	4	4
488	S:S:P720	S:S:T721	1.75	No	No	0	3	4
489	S:S:G801	S:S:M800	1.75	No	Yes	0	7	7
490	R:R:C640	R:R:V613	1.71	No	No	0	7	6
491	R:R:G806	R:R:L805	1.71	No	No	0	6	2
492	S:S:G620	S:S:L585	1.71	No	Yes	0	4	7
493	S:S:A636	S:S:S634	1.71	No	No	0	4	5
494	S:S:A693	S:S:S654	1.71	No	No	0	5	9
495	S:S:G809	S:S:L808	1.71	No	No	0	7	6
496	R:R:A570	R:R:V618	1.7	No	No	0	5	7
497	R:R:A635	R:R:V693	1.7	No	No	0	5	7
498	R:R:A782	S:S:V784	1.7	No	No	0	8	7
499	S:S:A797	S:S:V573	1.7	No	No	0	7	7
500	S:S:A674	S:S:V665	1.7	No	No	0	7	7
501	R:R:A825	R:R:T823	1.68	No	No	0	6	7
502	S:S:G609	S:S:Q605	1.64	No	No	0	8	7
503	S:S:L825	S:S:P826	1.64	No	No	0	6	9
504	R:R:N731	R:R:P638	1.63	No	No	0	7	5
505	R:R:N721	R:R:P722	1.63	No	No	0	6	6
506	R:R:S744	R:R:V740	1.62	No	No	0	4	2
507	S:S:S717	S:S:V718	1.62	No	No	0	3	6
508	S:S:A640	S:S:M644	1.61	No	No	0	6	5
509	R:R:S628	R:R:T629	1.6	No	No	0	4	6
510	R:R:S719	R:R:T705	1.6	No	No	0	5	3
511	R:R:C632	R:R:L636	1.59	No	No	0	6	6
512	R:R:T778	R:R:V774	1.59	No	No	13	8	6
513	R:R:T778	S:S:V781	1.59	No	No	13	8	6
514	S:S:T741	S:S:V696	1.59	Yes	No	0	8	5
515	S:S:A698	S:S:L647	1.58	No	No	0	4	7
516	S:S:A686	S:S:L658	1.58	No	No	0	7	7
517	S:S:A693	S:S:L745	1.58	No	No	0	5	9
518	S:S:A793	S:S:L724	1.58	No	Yes	0	8	6
519	S:S:P760	S:S:Q759	1.58	No	No	0	9	8
520	S:S:A788	S:S:N789	1.56	No	No	0	6	8
521	R:R:I586	R:R:V585	1.54	No	No	0	5	1
522	R:R:K626	R:R:S628	1.53	No	No	0	5	4
523	S:S:M644	S:S:S625	1.53	No	No	0	5	8
524	R:R:M690	R:R:V694	1.52	No	No	0	4	4
525	R:R:M697	R:R:V694	1.52	Yes	No	0	7	4
526	S:S:I740	S:S:T741	1.52	No	Yes	0	5	8
527	S:S:M744	S:S:T741	1.51	No	Yes	0	5	8
528	S:S:F814	S:S:G768	1.51	Yes	No	0	9	5
529	S:S:G683	S:S:R682	1.5	No	No	0	6	7
530	R:R:L581	R:R:V585	1.49	No	No	0	3	1
531	R:R:L702	R:R:V627	1.49	Yes	No	0	8	4
532	R:R:L737	R:R:V741	1.49	No	No	0	4	4
533	S:S:L681	S:S:V665	1.49	No	No	0	5	7
534	S:S:L692	S:S:V696	1.49	No	No	0	4	5
535	S:S:L786	S:S:V798	1.49	No	No	0	7	8
536	R:R:L584	R:R:T609	1.47	No	No	0	4	4
537	R:R:I595	R:R:M814	1.46	Yes	No	0	7	8
538	R:R:P594	R:R:R597	1.44	Yes	No	0	8	7
539	R:R:K660	R:R:M661	1.44	No	Yes	0	6	7
540	R:R:F665	R:R:P666	1.44	No	No	0	5	7
541	S:S:P564	S:S:R563	1.44	No	No	0	4	2
542	S:S:Q641	S:S:S637	1.44	No	No	0	8	6
543	R:R:Q592	R:R:T593	1.42	No	No	0	4	9
544	R:R:A802	R:R:F768	1.39	No	No	0	7	7
545	R:R:P819	R:R:Y818	1.39	No	No	0	8	6
546	R:R:D712	R:R:K714	1.38	No	No	0	4	4
547	S:S:L575	S:S:L578	1.38	No	No	0	5	4
548	S:S:L581	S:S:L585	1.38	No	Yes	0	7	7
549	S:S:L589	S:S:L592	1.38	No	Yes	0	4	5
550	S:S:L624	S:S:L627	1.38	No	No	0	6	7
551	S:S:L671	S:S:N675	1.37	No	No	0	5	6
552	R:R:N723	R:R:N726	1.36	No	No	0	5	2
553	S:S:A793	S:S:Y794	1.33	No	No	0	8	4
554	R:R:R664	R:R:S663	1.32	No	No	0	7	5
555	R:R:R674	R:R:S670	1.32	No	No	0	7	4
556	R:R:F770	R:R:V740	1.31	No	No	0	6	2
557	R:R:E751	S:S:Q757	1.27	No	No	0	7	9
558	R:R:F827	R:R:N828	1.21	Yes	No	0	7	6
559	S:S:L688	S:S:W685	1.14	No	No	0	4	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F587	4.38667	6	3	9
2	R:R:P594	4.476	5	9	8
3	R:R:I595	8.8325	4	0	7
4	R:R:F605	4.2775	4	0	6
5	R:R:Y615	5.95833	6	8	8
6	R:R:F653	6.56	4	2	7
7	R:R:M661	5.92	4	0	7
8	R:R:Y669	5.95	5	2	7
9	R:R:W672	6.61833	6	2	6
10	R:R:P678	4.95	4	2	8
11	R:R:K689	6.29167	6	10	9
12	R:R:M697	4.285	4	0	7
13	R:R:L702	3.1625	4	0	8
14	R:R:D709	7.9625	4	0	3
15	R:R:I715	4.6375	4	0	4
16	R:R:Y724	5.145	4	0	8
17	R:R:F745	4.63833	6	2	7
18	R:R:N755	3.7325	4	3	8
19	R:R:E758	6.818	5	3	9
20	R:R:I762	3.615	4	3	9
21	R:R:Y769	6.584	5	0	8
22	R:R:Y783	7.042	5	0	8
23	R:R:I790	4.16	4	7	8
24	R:R:L793	7.2975	4	0	8
25	R:R:Y807	5.17667	6	3	8
26	R:R:F808	6.2575	4	3	9
27	R:R:F827	5.54	4	0	7
28	S:S:L567	3.7925	4	15	9
29	S:S:E571	4.22	5	0	7
30	S:S:L585	2.8475	4	0	7
31	S:S:L592	2.595	4	0	5
32	S:S:L603	6.86	5	0	8
33	S:S:F612	5.835	4	4	8
34	S:S:P630	5.8275	4	15	7
35	S:S:P633	3.865	4	5	9
36	S:S:L653	5.035	4	1	7
37	S:S:E697	6.7475	4	0	9
38	S:S:Y704	4.76	4	0	7
39	S:S:L719	3.91	4	14	4
40	S:S:L724	3.88	5	0	6
41	S:S:H739	7.6075	4	0	7
42	S:S:T741	2.36	5	0	8
43	S:S:N742	8.6425	4	1	8
44	S:S:F747	6.22	4	0	3
45	S:S:F754	6.462	5	0	9
46	S:S:L755	6.1225	4	0	8
47	S:S:Y763	7.3425	4	4	9
48	S:S:R765	5.885	4	0	9
49	S:S:L769	5.148	5	4	9
50	S:S:Y776	7.096	5	1	8
51	S:S:W780	8.948	5	1	9
52	S:S:L787	6.2875	4	1	8
53	S:S:M800	4.762	5	0	7
54	S:S:L811	3.8275	4	0	8
55	S:S:F814	6.548	5	4	9
56	S:S:H815	7.01	5	0	9
57	S:S:K818	5.832	5	4	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:R633	R:R:Y621	14.6189	17.49	No	No	0	8	8
2	R:R:D792	R:R:Y621	34.6829	5.75	No	No	0	9	8
3	R:R:D792	R:R:L728	35.8485	4.07	No	No	0	9	7
4	R:R:L728	R:R:M780	36.4137	8.48	No	No	0	7	8
5	R:R:M780	R:R:Y724	17.2585	8.38	No	Yes	0	8	8
6	R:R:V788	R:R:Y724	14.6033	5.05	No	Yes	0	7	8
7	R:R:V788	R:R:Y783	13.9331	2.52	No	Yes	0	7	8
8	R:R:G785	R:R:Y783	10.5584	7.24	No	Yes	0	7	8
9	R:R:L793	R:R:Y621	21.179	18.76	Yes	No	0	8	8
10	R:R:L800	R:R:Y615	10.5584	8.21	No	Yes	0	8	8
11	R:R:F641	R:R:L800	11.9171	2.44	No	No	0	8	8
12	R:R:F641	R:R:Y769	70.1204	6.19	No	Yes	0	8	8
13	R:R:N799	R:R:Y769	52.5819	8.14	No	Yes	0	9	8
14	R:R:N799	R:R:V795	51.4669	4.43	No	No	12	9	8
15	R:R:L776	R:R:V795	51.0689	7.45	No	No	0	9	8
16	R:R:L776	R:R:M780	50.5594	2.83	No	No	0	9	8
17	R:R:F808	R:R:Y807	32.2975	9.28	Yes	Yes	3	9	8
18	R:R:I648	R:R:Y807	13.3108	3.63	No	Yes	3	7	8
19	R:R:I648	R:R:I803	81.5773	2.94	No	No	0	7	8
20	R:R:I645	R:R:I803	77.2445	2.94	No	No	0	7	8
21	R:R:F641	R:R:I645	76.897	8.79	No	No	0	8	7
22	R:R:C812	R:R:F587	21.6341	4.19	No	Yes	0	7	9
23	R:R:F587	R:R:F808	27.7806	3.22	Yes	Yes	3	9	9
24	R:R:C812	R:R:I586	21.0986	4.91	No	No	0	7	5
25	R:R:H590	R:R:I586	19.1656	2.65	No	No	0	5	5
26	R:R:H590	R:R:I815	18.5161	6.63	No	No	0	5	8
27	R:R:I595	R:R:I815	17.8639	8.83	Yes	No	0	7	8
28	R:R:I595	R:R:Y756	10.3911	10.88	Yes	No	0	7	9
29	R:R:D735	R:R:K689	16.5779	5.53	No	Yes	10	8	9
30	R:R:D735	R:R:Y769	17.921	4.6	No	Yes	0	8	8
31	R:R:I648	R:R:I762	68.5828	2.94	No	Yes	3	7	9
32	R:R:I762	R:R:S652	19.2097	4.64	Yes	No	0	9	9
33	R:R:F745	R:R:S652	17.9028	2.64	Yes	No	0	7	9
34	R:R:A746	R:R:T763	100	3.36	No	No	0	9	9
35	R:R:A746	R:R:I762	99.9313	3.25	No	Yes	0	9	9
36	R:R:T763	S:S:L755	99.0756	5.9	No	Yes	0	9	8
37	S:S:L653	S:S:Y776	17.5489	3.52	Yes	Yes	1	7	8
38	S:S:L653	S:S:M773	69.0288	2.83	Yes	No	0	7	9
39	S:S:F750	S:S:M773	53.5931	3.73	No	No	0	8	9
40	S:S:F750	S:S:F754	53.5867	16.08	No	Yes	0	8	9
41	S:S:F754	S:S:L755	99.9572	7.31	Yes	Yes	0	9	8
42	S:S:L649	S:S:L653	36.8623	6.92	No	Yes	1	8	7
43	S:S:F622	S:S:L649	38.0058	14.61	No	No	0	6	8
44	S:S:F622	S:S:I803	37.6104	8.79	No	No	0	6	9
45	S:S:I803	S:S:V626	35.3467	4.61	No	No	0	9	7
46	S:S:M800	S:S:V626	33.3761	3.04	Yes	No	0	7	7
47	S:S:F629	S:S:M800	14.4089	4.98	No	Yes	0	9	7
48	S:S:F629	S:S:Q641	12.1206	16.4	No	No	0	9	8
49	S:S:M800	S:S:P630	22.0282	8.39	Yes	Yes	0	7	7
50	S:S:L567	S:S:P630	15.2295	3.28	Yes	Yes	15	9	7
51	S:S:E571	S:S:L567	14.0005	2.65	Yes	Yes	0	7	9
52	S:S:E571	S:S:Y794	10.5973	7.86	Yes	No	0	7	4
53	S:S:L804	S:S:V626	15.7689	4.47	No	No	0	8	7
54	S:S:L581	S:S:L804	10.6193	4.15	No	No	0	7	8
55	S:S:F754	S:S:T770	49.39	3.89	Yes	No	0	9	9
56	S:S:T753	S:S:T770	47.6139	4.71	No	No	0	9	9
57	S:S:L769	S:S:T753	47.6294	5.9	Yes	No	0	9	9
58	S:S:F814	S:S:L769	47.3079	8.53	Yes	Yes	4	9	9
59	S:S:F814	S:S:H815	19.2888	7.92	Yes	Yes	0	9	9
60	S:S:F612	S:S:H815	15.0052	9.05	Yes	Yes	0	8	9
61	S:S:F612	S:S:S595	31.6103	6.61	Yes	No	0	8	9
62	S:S:C613	S:S:S595	30.7871	3.44	No	No	0	7	9
63	S:S:C613	S:S:L592	11.1223	3.17	No	Yes	0	7	5
64	S:S:F814	S:S:K818	28.6531	8.69	Yes	Yes	4	9	9
65	S:S:F612	S:S:K818	18.5757	3.72	Yes	Yes	4	8	9
66	S:S:K818	S:S:L603	13.0593	7.05	Yes	Yes	0	9	8
67	S:S:C613	S:S:W599	24.9569	3.92	No	No	0	7	5
68	S:S:L769	S:S:Q659	16.7788	3.99	Yes	No	0	9	9
69	S:S:Q659	S:S:R765	16.2252	5.84	No	Yes	0	9	9
70	S:S:S610	S:S:W599	22.8411	2.47	No	No	0	5	5
71	S:S:S610	S:S:W687	21.7793	2.47	No	No	0	5	4
72	S:S:F614	S:S:W687	15.354	7.02	No	No	0	5	4
73	S:S:C618	S:S:F614	14.274	8.38	No	No	0	8	5
74	S:S:L653	S:S:N742	18.1621	6.87	Yes	Yes	1	7	8
75	S:S:N742	S:S:T650	15.5251	8.77	Yes	No	0	8	8
76	S:S:E697	S:S:T650	14.8445	12.7	Yes	No	0	9	8
77	S:S:W780	S:S:Y776	10.9201	16.4	Yes	Yes	1	9	8
78	S:S:E697	S:S:T741	10.7217	4.23	Yes	Yes	0	9	8
79	S:S:C618	S:S:G651	12.1064	1.96	No	No	0	8	7
80	S:S:C749	S:S:M773	17.5334	6.48	No	No	0	9	9
81	S:S:E662	S:S:R765	13.596	8.14	No	Yes	0	8	9
82	S:S:E662	S:S:L681	10.1085	2.65	No	No	0	8	5
83	R:R:I762	R:R:Y807	28.2292	3.63	Yes	Yes	3	9	8
84	S:S:C749	S:S:L769	16.8203	3.17	No	Yes	0	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 9OPX

PDB Summary
PDB	9OPX
Class	C
SubFamily	Sensory
Type	Taste1
SubType	TAS1R2 ; TAS1R3
Species	Homo Sapiens; Mus Musculus
Ligand	-
Other Ligand(s)	-
Protein Partners	-
PDB Resolution	3.63
Date	2025-09-03
D.O.I.	To be published

Net Summary
I_min	2.82
Number of Linked Nodes	514
Number of Links	559
Number of Hubs	57
Number of Links mediated by Hubs	223
Number of Communities	17
Number of Nodes involved in Communities	82
Number of Links involved in Communities	96

Path Summary
Number Of Nodes in MetaPath	85
Number Of Links MetaPath	84
Number of Shortest Paths	150695
Length Of Smallest Path	3
Average Path Length	19.6175
Length of Longest Path	46
Minimum Path Strength	1.455
Average Path Strength	5.58321
Maximum Path Strength	18.125
Minimum Path Correlation	0.7
Average Path Correlation	0.962796
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.7037
Average % Of Corr. Nodes	51.4394
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	33.2689
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• sensory perception of sweet taste • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • sensory perception of umami taste • response to stimulus • detection of chemical stimulus involved in sensory perception of sweet taste • detection of chemical stimulus involved in sensory perception of taste • detection of stimulus • response to chemical • detection of chemical stimulus • detection of stimulus involved in sensory perception • detection of chemical stimulus involved in sensory perception • cellular response to stimulus • regulation of biological process • regulation of cellular process • signaling • biological regulation • G protein-coupled receptor signaling pathway • cellular process • signal transduction • cell communication • membrane-bounded organelle • intracellular organelle • cellular anatomical structure • intracellular anatomical structure • Golgi apparatus • organelle • cytoplasm • intracellular membrane-bounded organelle • endomembrane system • cell periphery • plasma membrane • membrane • protein-containing complex • taste receptor complex
Gene Ontology	Cellular Component	• membrane-bounded organelle • intracellular organelle • cellular anatomical structure • intracellular anatomical structure • Golgi apparatus • organelle • cytoplasm • intracellular membrane-bounded organelle • endomembrane system • cell periphery • plasma membrane • membrane • protein-containing complex • taste receptor complex • sweet taste receptor complex • receptor complex • taste receptor activity • molecular transducer activity • transmembrane signaling receptor activity • signaling receptor activity • G protein-coupled receptor activity • sweet taste receptor activity • sensory perception of sweet taste • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • regulation of cytokinesis • regulation of biological process • regulation of cellular process • positive regulation of cell division • regulation of cell cycle process • biological regulation • positive regulation of biological process • cytokinesis • positive regulation of cell cycle • regulation of cell division • positive regulation of cytokinesis • positive regulation of cell cycle process • cellular process • cell division • cell cycle • regulation of cell cycle • positive regulation of cellular process • cell cycle process • response to stimulus • detection of chemical stimulus involved in sensory perception of sweet taste • detection of chemical stimulus involved in sensory perception of taste • detection of stimulus • response to chemical • detection of chemical stimulus • detection of stimulus involved in sensory perception • detection of chemical stimulus involved in sensory perception • cellular response to stimulus • signaling • G protein-coupled receptor signaling pathway • signal transduction • cell communication
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q8TE23
Sequence	>9OPX_Chain_R R Q L V F L E W H E A P T I A V A L L A A L G F L S T L A I L V I F W R H F Q T P I V R S A G G P M C F L M L T L L L V A Y M V V P V Y V G P P K V S T C L C R Q A L F P L C F T I C I S C I A V R S F Q I V C A F K M A S R F P R A Y S Y W V R Y Q G P Y V S M A F I T V L K M V I V V I G M L A T G L S P T T R T D P D D P K I T I V S C N P N Y R N S L L F N T S L D L L L S V V G F S F A Y M G K E L P T N Y N E A K F I T L S M T F Y F T S S V S L C T F M S A Y S G V L V T I V D L L V T V L N L L A I S L G Y F G P K C Y M I L F Y P E R N T P A Y F N S M I Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	S
Protein	Receptor
UniProt	Q925D8
Sequence	>9OPX_Chain_S P R R P K F L A W G E P V V L S L L L L L C L V L G L A L A A L G L S V H H W D S P L V Q A S G G S Q F C F G L I C L G L F C L S V L L F P G R P S S A S C L A Q Q P M A H L P L T G C L S T L F L Q A A E T F V E S E L P L S W A N W L C S Y L R G L W A W L V V L L A T F V E A A L C A W Y L I A F P P E V V T D W S V L P T E V L E H C H V R S W V S L G L V H I T N A M L A F L C F L G T F L V Q S Q P G R Y N R A R G L T F A M L A Y F I T W V S F V P L L A N V Q V A Y Q P A V Q M G A I L V C A L G I L V T F H L P K C Y V L L W L P K L N T Q E F F L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9OPY	C	Sensory	Taste1	TAS1R2 ; TAS1R3	Homo sapiens; mus musculus	-	-	-	3.51	2025-09-03	To be published

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