Orange: nodes, hubs and links specific of beta2_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of beta2_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner beta2_on_gp Avg Int. Strength beta2_off Avg Int. Strength beta2_on_gp Num Of Links beta2_off Num Of Links ConSurf
1G.HN.41 beta2_on_gp00404
2G.S2.03 beta2_on_gp00409
3G.S3.03 beta2_on_gp500408
4G.S3.04 beta2_on_gp1000407
5G.S3.06 beta2_on_gp500407
6G.s3h2.03 beta2_on_gp00409
7G.H2.01 beta2_on_gp00409
8G.H2.06 beta2_on_gp1000509
9G.H2.07 beta2_on_gp500509
10G.H2.10 beta2_on_gp1000408
11G.s4h3.02 beta2_on_gp00409
12G.H3.09 beta2_on_gp1000609
13G.H3.13 beta2_on_gp1000506
14G.H3.17 beta2_on_gp500405
15G.S5.04 beta2_on_gp500409
16G.S5.05 beta2_on_gp500609
17G.s5hg.01 beta2_on_gp500409
18G.HG.01 beta2_on_gp500406
19G.HG.03 beta2_on_gp00406
20G.hgh4.13 beta2_on_gp00404
21G.hgh4.20 beta2_on_gp00403
22G.hgh4.21 beta2_on_gp500404
23G.H4.03 beta2_on_gp500404
24G.H4.10 beta2_on_gp1000507
25G.H4.12 beta2_on_gp1000504
26G.H4.15 beta2_on_gp500408
27G.h4s6.20 beta2_on_gp1000504
28G.S6.02 beta2_on_gp500408
29G.S6.05 beta2_on_gp500405
30G.s6h5.01 beta2_on_gp500409
31G.H5.08 beta2_on_gp500508
32G.H5.16 beta2_on_gp500406
33G.H5.17 beta2_on_gp1000405
34g.l1x4 beta2_on_gp00408
35g.h2x11 beta2_on_gp500406
36g.ctx3 beta2_on_gp1000409
37g.ctx6 beta2_on_gp00406
38g.ctx14 beta2_on_gp500409
39g.ctx16 beta2_on_gp1000608
402x46 beta2_on_gp500429
412x50 beta2_on_gp1000529
423x34 beta2_on_gp00435
433x50 beta2_on_gp5085.7143439
44I2x50 beta2_on_gp00418
45I2x51 beta2_on_gp500426
464x57 beta2_on_gp00437
474x58 beta2_on_gp014.2857534
48E2.Y185 beta2_on_gp00431
495x48 beta2_on_gp00425
505x62 beta2_on_gp00426
515x72 beta2_on_gp00406
526x37 beta2_on_gp00418
536x49 beta2_on_gp00426
547x39 beta2_on_gp5028.5714535
557x45 beta2_on_gp500439
567x49 beta2_on_gp5028.5714439
577x55 beta2_on_gp500437
588x54 beta2_on_gp00437
59b.1x13 beta2_on_gp00507
60b.lh12x2 beta2_on_gp00408
61b.lhb1x6 beta2_on_gp500403
62b.b1x6 beta2_on_gp500409
63b.l1x3 beta2_on_gp1000509
64b.l1x6 beta2_on_gp1000509
65b.b2x1 beta2_on_gp1000508
66b.b2x5 beta2_on_gp500507
67b.b3x3 beta2_on_gp500508
68b.l3x1 beta2_on_gp1000409
69b.l3x2 beta2_on_gp1000509
70b.b4x6 beta2_on_gp1000709
71b.b4x7 beta2_on_gp1000408
72b.l4x2 beta2_on_gp500404
73b.b5x3 beta2_on_gp1000409
74b.b5x7 beta2_on_gp1000407
75b.l5x1 beta2_on_gp500508
76b.l5x5 beta2_on_gp1000509
77b.b6x1 beta2_on_gp500409
78b.b6x5 beta2_on_gp1000406
79b.l6x5 beta2_on_gp1000404
80b.b7x1 beta2_on_gp500404
81b.b8x3 beta2_on_gp500406
82b.b8x4 beta2_on_gp1000506
83b.l9x3 beta2_on_gp1000409
84b.l9x6 beta2_on_gp1000808
85b.b10x5 beta2_on_gp500609
86b.b11x4 beta2_on_gp500509
87b.l11x2 beta2_on_gp1000409
88b.b12x5 beta2_on_gp500506
89b.b12x6 beta2_on_gp1000508
90b.b13x7 beta2_on_gp1000507
91b.l13x3 beta2_on_gp1000509
92b.l13x6 beta2_on_gp500509
93b.b15x2 beta2_on_gp500406
94b.l15x1 beta2_on_gp1000507
95b.b16x4 beta2_on_gp500406
96b.b16x6 beta2_on_gp1000608
97b.l17x3 beta2_on_gp1000809
98b.b18x3 beta2_on_gp1000408
99b.b18x5 beta2_on_gp500505
100b.l18x1 beta2_on_gp1000706
101b.b19x2 beta2_on_gp1000606
102b.b19x4 beta2_on_gp1000408
103b.l19x1 beta2_on_gp00409
104b.l19x2 beta2_on_gp1000509
105b.b20x2 beta2_on_gp500506
106b.b20x4 beta2_on_gp1000508
107b.b20x6 beta2_on_gp1000606
108b.b21x1 beta2_on_gp500507
109b.b21x7 beta2_on_gp500605
110b.b23x6 beta2_on_gp1000607
111b.l23x1 beta2_on_gp500406
112b.b24x4 beta2_on_gp500406
113b.b24x6 beta2_on_gp500408
114b.b25x3 beta2_on_gp500405
115b.l25x3 beta2_on_gp1000509
116b.l25x6 beta2_on_gp1000508
117b.l27x1 beta2_on_gp1000609
118b.l27x2 beta2_on_gp500409
119b.b28x4 beta2_on_gp1000406
120b.b28x6 beta2_on_gp1000609
1211x60 Shared500446
1222x42 Shared071.4286448
123E1x50 Shared100100677
124E1x52 Shared071.4286455
1253x28 Shared5057.1429545
1263x51 Shared5014.2857448
1274x50 Shared00449
128E2.Y174 Shared5085.7143455
1295x39 Shared10085.7143456
1305x47 Shared10014.2857548
1315x50 Shared10042.8571448
1325x58 Shared100100579
1336x48 Shared10085.7143668
1346x51 Shared10085.7143666
1356x52 Shared10085.7143657
1367x37 Shared00445
1377x42 Shared100100676
1387x53 Shared50100559
1398x50 Shared100100669
140Lig Shared10010013120
1411x39 beta2_off028.5714356
1422x53 beta2_off5028.5714347
1433x24 beta2_off0100255
1443x27 beta2_off028.5714145
1453x49 beta2_off057.1429348
146E2x51 beta2_off5028.5714343
147E2x52 beta2_off057.1429244
148E2.F194 beta2_off085.7143341
1495x60 beta2_off00245
1505x64 beta2_off085.7143155
1516x31 beta2_off042.8571145
1526x44 beta2_off50100359
1536x59 beta2_off00345
   
Orange: nodes, hubs and links specific of beta2_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of beta2_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner beta2_on_gp Recurrence beta2_off Recurrence beta2_on_gp Hub1? beta2_off Hub1? beta2_on_gp Hub2? beta2_off Hub2? ConSurf1 ConSurf2
1b.b4x2 b.l3x2 beta2_on_gp18.9810NoNoYesNo89
2G.hns1.01 b.l3x2 beta2_on_gp24.09270NoNoYesNo49
3G.S1.03 G.hns1.01 beta2_on_gp32.10970NoNoNoNo94
4G.S1.03 b.l5x5 beta2_on_gp24.09340NoNoYesNo99
5b.b2x3 b.b2x5 beta2_on_gp13.49930NoNoYesNo67
6b.b26x2 b.b2x3 beta2_on_gp13.78320NoNoNoNo76
7b.b26x1 b.b26x2 beta2_on_gp13.92890NoNoNoNo97
8b.b26x1 b.l27x1 beta2_on_gp14.07940NoNoYesNo99
9b.b2x1 b.l27x1 beta2_on_gp39.94260YesNoYesNo89
10b.b2x1 b.b6x1 beta2_on_gp58.48190YesNoYesNo89
11b.b6x1 b.l9x6 beta2_on_gp81.07130YesNoYesNo98
12G.H2.07 b.l9x6 beta2_on_gp99.17810YesNoYesNo98
13G.H2.04 G.H2.07 beta2_on_gp99.79650NoNoYesNo99
14G.H2.04 G.H3.08 beta2_on_gp99.84360NoNoNoNo98
15G.H3.08 G.S4.04 beta2_on_gp1000NoNoNoNo89
16G.H3.09 G.S4.04 beta2_on_gp66.54950YesNoNoNo99
17G.H3.09 G.H4.15 beta2_on_gp33.72970YesNoYesNo98
18G.H4.15 G.S5.04 beta2_on_gp65.73590YesNoYesNo89
19G.S5.04 G.S6.03 beta2_on_gp90.6340YesNoNoNo95
20G.H4.12 G.S6.03 beta2_on_gp90.26340YesNoNoNo45
21G.H4.12 G.H4.13 beta2_on_gp90.09140YesNoNoNo43
22G.H4.13 I3.R239 beta2_on_gp87.85250NoNoNoNo34
23I3.F240 I3.R239 beta2_on_gp87.67620NoNoNoNo44
24G.h4s6.03 I3.F240 beta2_on_gp87.50560NoNoNoNo44
255x76 G.h4s6.03 beta2_on_gp87.32910NoNoNoNo34
265x76 G.h4s6.20 beta2_on_gp86.97560NoNoYesNo34
27G.H5.17 G.h4s6.20 beta2_on_gp74.66670YesNoYesNo54
285x68 G.H5.17 beta2_on_gp76.08180NoNoYesNo75
295x68 G.H5.16 beta2_on_gp75.3350NoNoYesNo76
30G.S4.04 G.S4.06 beta2_on_gp33.50540NoNoNoNo97
31G.H4.15 G.S4.06 beta2_on_gp33.45070YesNoNoNo87
32G.H3.09 G.S6.01 beta2_on_gp32.85620YesNoNoNo95
33G.S5.04 G.S6.01 beta2_on_gp32.98860YesNoNoNo95
34G.h2s4.01 b.l5x5 beta2_on_gp10.5150NoNoYesNo99
35G.S6.02 G.h4s6.20 beta2_on_gp10.31340YesNoYesNo84
36G.H5.10 G.S6.02 beta2_on_gp11.01470NoNoYesNo78
37b.b14x1 b.l9x6 beta2_on_gp17.27010NoNoYesNo88
38G.H2.06 b.b14x1 beta2_on_gp17.10110YesNoNoNo98
39G.H2.06 b.l19x1 beta2_on_gp17.28930YesNoYesNo99
40b.l25x6 b.l27x1 beta2_on_gp27.6020YesNoYesNo89
41G.H2.10 G.h2s4.01 beta2_on_gp11.55730YesNoNoNo89
42G.H2.10 b.l3x1 beta2_on_gp10.5850YesNoYesNo89
43b.l3x1 b.l5x5 beta2_on_gp21.57330YesNoYesNo99
44b.l23x1 b.l25x6 beta2_on_gp10.9950YesNoYesNo68
45G.H5.16 I2x50 beta2_on_gp71.09850YesNoYesNo68
46G.H5.15 I2x50 beta2_on_gp70.80640NoNoYesNo88
47G.H5.15 G.H5.19 beta2_on_gp70.61550NoNoNoNo88
483x53 G.H5.19 beta2_on_gp70.23320NoNoNoNo88
493x46 3x50 beta2_on_gp19.94650NoNoYesNo99
502x42 3x46 beta2_on_gp20.14581.31487YesYesNoNo89
513x49 I2x53 beta2_on_gp68.50520NoYesNoNo87
523x53 I2x53 beta2_on_gp70.04180NoNoNoNo87
53b.l17x5 b.l19x1 beta2_on_gp16.94270NoNoYesNo69
54b.l17x5 b.l19x2 beta2_on_gp16.76540NoNoYesNo69
55b.l17x3 b.l19x2 beta2_on_gp15.11710YesNoYesNo99
56b.b20x6 b.l17x3 beta2_on_gp11.45460YesNoYesNo69
57b.b10x1 b.l9x6 beta2_on_gp10.28050NoNoYesNo98
58b.b10x1 b.b11x5 beta2_on_gp10.10440NoNoNoNo96
59b.l21x7 b.l23x1 beta2_on_gp11.30450NoNoYesNo56
60b.l21x7 b.l23x2 beta2_on_gp11.14750NoNoNoNo58
61b.b22x1 b.l25x6 beta2_on_gp15.30190NoNoYesNo88
62b.b22x1 b.b22x2 beta2_on_gp15.63030NoNoNoNo88
63b.b22x2 b.b26x3 beta2_on_gp15.48060NoNoNoNo86
64b.b24x3 b.b26x3 beta2_on_gp12.41450NoNoNoNo56
65b.b24x3 b.b25x7 beta2_on_gp12.09460NoNoNoNo57
662x46 3x42 beta2_on_gp14.27510YesNoNoNo98
672x45 3x42 beta2_on_gp14.66131.44986NoNoNoNo98
68b.b25x7 b.b28x6 beta2_on_gp11.60250NoNoYesNo79
693x43 7x53 beta2_on_gp13.13250NoNoYesYes89
703x50 7x53 beta2_on_gp14.1860YesNoYesYes99
713x43 7x49 beta2_on_gp12.85210NoNoYesNo89
726x48 7x45 beta2_on_gp21.94840YesYesYesNo89
737x45 7x49 beta2_on_gp23.59810YesNoYesNo99
746x48 6x52 beta2_on_gp13.82386.42936YesYesYesYes87
755x47 6x49 beta2_on_gp12.76374.34457YesYesYesNo86
766x49 6x50 beta2_on_gp10.08130YesNoNoNo69
77b.b4x2 b.b5x8 beta2_on_gp17.23920NoNoNoNo85
78b.b5x7 b.b5x8 beta2_on_gp16.66580YesNoNoNo75
79b.l11x1 b.l9x6 beta2_on_gp15.09220NoNoYesNo98
80b.b11x6 b.l11x1 beta2_on_gp15.61760NoNoNoNo99
81b.b11x6 b.l9x3 beta2_on_gp14.50820NoNoYesNo99
82b.b8x3 b.b9x4 beta2_on_gp11.77120YesNoNoNo69
83b.b2x1 b.l3x1 beta2_on_gp10.93690YesNoYesNo89
84G.H2.10 b.b6x1 beta2_on_gp22.12310YesNoYesNo89
852x42 3x49 Shared68.119413.5436YesYesNoYes88
863x33 Lig Shared22.594335.0915NoNoYesYes50
873x33 4x57 Shared22.787233.8966NoNoYesNo57
883x34 4x57 Shared23.161130.252YesNoYesNo57
893x34 4x50 Shared30.865427.7722YesNoYesYes59
902x45 4x50 Shared32.610423.9776NoNoYesYes99
912x45 4x46 Shared47.383921.3979NoNoNoNo98
922x42 4x46 Shared47.587820.093YesYesNoNo88
932x46 7x49 Shared11.201189.996YesNoYesNo99
945x47 6x52 Shared14.116312.7737YesYesYesYes87
95E2x52 Lig beta2_off0.74046364.0186NoYesYesYes40
965x43 Lig beta2_off2.6585312.0588NoNoYesYes50
976x48 Lig beta2_off085.0215YesYesYesYes80
986x51 Lig beta2_off0.98828510.294YesYesYesYes60
991x31 1x35 beta2_off1.0202612.5937NoNoNoNo35
1001x35 1x39 beta2_off1.7838514.0236NoNoNoYes56
1011x39 7x39 beta2_off2.2921321.7278NoYesYesNo65
1027x39 7x42 beta2_off7.5716124.3926YesNoYesYes56
1032x53 7x46 beta2_off1.2376124.5575NoYesNoNo79
1042x53 7x42 beta2_off029.707NoYesYesYes76
1051x50 2x47 beta2_off010.459NoNoNoNo99
1061x50 2x50 beta2_off0.48293217.6332NoNoYesNo99
1072x50 7x46 beta2_off2.0968919.0381YesNoNoNo99
1081x52 8x54 beta2_off0.84862416.4184NoNoYesNo67
1098x50 8x54 beta2_off1.1842419.0981YesYesYesNo97
1107x53 8x50 beta2_off040.5109YesYesYesYes99
1117x49 7x53 beta2_off034.2216YesNoYesYes99
1122x46 3x43 beta2_off0.089054690.5409YesNoNoNo98
1133x43 6x44 beta2_off091.0759NoNoNoYes89
1146x44 6x48 beta2_off0100NoYesYesYes98
1151x52 8x57 beta2_off011.1639NoNoNoNo66
1168x47 8x50 beta2_off0.50961616.3434NoNoYesYes89
1178x47 8x49 beta2_off0.16997712.2788NoNoNoNo87
1188x49 I1x49 beta2_off010.9039NoNoNoNo76
1193x24 3x27 beta2_off022.1878NoYesNoYes55
1203x27 4x58 beta2_off0.23668926.1624NoYesYesNo54
1213x30 4x58 beta2_off5.7487627.0923NoNoYesNo64
1223x30 4x61 beta2_off5.5166529.587NoNoNoNo65
1234x61 E2.Y174 beta2_off5.3073530.8519NoNoYesYes55
124E2.Y174 E2x52 beta2_off056.7643YesYesNoYes54
1253x24 E1x50 beta2_off010.004NoYesYesYes57
1263x40 6x44 beta2_off2.231112.7287NoNoNoYes79
1273x40 5x50 beta2_off2.3656311.3539NoNoYesYes78
1286x40 7x49 beta2_off055.1645NoNoYesNo89
1296x40 7x52 beta2_off063.7136NoNoNoNo88
1306x39 7x52 beta2_off062.7887NoNoNoNo78
1316x39 7x55 beta2_off0.25429561.8288NoNoYesNo77
1326x35 7x55 beta2_off059.914NoNoYesNo77
1336x26 6x35 beta2_off059.1341NoNoNoNo07
1345x62 6x26 beta2_off056.1494YesNoNoNo60
1355x58 5x62 beta2_off055.3295YesYesYesNo96
1365x58 5x61 beta2_off046.9303YesYesNoNo98
1373x54 5x61 beta2_off0.25326945.8354NoNoNoNo98
1383x54 5x64 beta2_off044.7305NoNoNoYes95
1393x55 5x64 beta2_off013.4637NoNoNoYes75
1403x51 3x55 beta2_off0.28311112.1638YesYesNoNo87
1415x60 5x64 beta2_off017.4983NoYesNoYes55
1423x51 5x60 beta2_off0.56614412.2988YesYesNoYes85
1433x51 3x52 beta2_off0.56614419.0681YesYesNoNo85
1443x52 I2x56 beta2_off013.6686NoNoNoNo54
1453x56 I2x56 beta2_off010.9539NoNoNoNo64
1465x64 5x68 beta2_off013.8086NoYesNoNo57
1475x68 I2x52 beta2_off012.4938NoNoNoNo75
148I2x52 I2x53 beta2_off011.1189NoNoNoNo57
1495x39 5x43 beta2_off2.4138711.4289YesYesNoNo65
1504x60 5x39 beta2_off3.2704710.039NoNoYesYes56
151E2.Y174 E2.Y185 beta2_off1.7438331.1519YesYesYesNo51
152E2.A181 E2.Y185 beta2_off030.352NoNoYesNo41
153E2.A181 E2.F194 beta2_off0.25524225.0525NoNoNoYes41
154E2.C190 E2.E187 beta2_off0.255414.3686NoNoNoNo34
155E2.F194 E2x51 beta2_off1.5163812.5937NoYesNoYes13
1565x40 E2.T195 beta2_off0.24924210.074NoNoNoNo53
1576x44 7x45 beta2_off014.0936NoYesYesNo99
1586x47 7x45 beta2_off0.47227311.3539NoNoYesNo99
1596x51 7x37 beta2_off019.4931YesYesYesYes65
1606x54 7x37 beta2_off5.3810911.5438NoNoYesYes55
1617x42 Lig beta2_off8.5975652.5047YesYesYesYes60

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
3x32LigShared18.547117.151210
3x33LigShared10.97438.4850010
3x36LigShared6.182866.9251010
E2x52LigShared8.5214310.8450010
5x43LigShared6.211434.9150010
5x461LigShared3.897144.520010
6x48Ligbeta2_off3.7342901210
6x51LigShared8.564297.6551210
6x52LigShared12.10575.661210
6x55LigShared8.565715.9450210
7x38LigShared14.667113.221210
7x42LigShared5.623.4551210
2x532x56beta2_off6.5228601022
2x537x42beta2_off3.9328601021
2x563x32Shared6.674298.031221
2x567x42Shared4.334.421221
2x577x42Shared3.788575.680221
2x593x24beta2_off17.1802222
2x593x28Shared5.727146.0152221
2x63E1x50beta2_off7.2542900012
3x24E1x50beta2_off4.5514302022
3x28E1x50Shared11.112911.7152212
3x243x28beta2_off5.6242902021
3x29E2x52beta2_off5.5600021
3x327x42Shared9.369.771211
3x334x57Shared5.537143.230012
3x366x48Shared7.355718.5851011
3x375x461Shared7.764299.590021
3x406x44Shared6.286.9050022
E2.Y174E2x52beta2_off3.9785708021
5x39E2.Y174Shared6.525715.460022
E2.T195E2x52Shared7.785.1850021
5x39E2.T195Shared5.528574.9950022
5x395x43Shared13.262914.6250021
5x446x52Shared3.966.6050021
5x475x48Shared8.251436.7050222
5x476x52Shared31.844319.8250221
6x446x48beta2_off12.027100021
6x447x45beta2_off6.5585700022
6x486x51Shared4.437143.511211
6x486x52Shared5.155714.511211
6x487x41Shared12.6711.9651212
6x516x52Shared6.124296.971211
6x517x34Shared10.90434.1251212
6x517x38Shared12.425715.1051211
6x557x34Shared5.647146.9750212
7x387x42Shared12.79439.3051211
7x397x42Shared14.46718.21221
2x603x28Shared2.611432.110021
6x517x37beta2_off2.0914301212
2x533x36beta2_on_gp03.81021
2x577x39beta2_on_gp04.290222
3x28Ligbeta2_on_gp04.2552210
3x406x48beta2_on_gp05.2850021
5x476x44beta2_on_gp06.9650222
5x486x52beta2_on_gp03.610221
6x487x45beta2_on_gp07.3451212
6x516x55beta2_on_gp06.041211
2x59E1x50beta2_on_gp03.512222
3x283x29beta2_on_gp03.0352212
2x63Ligbeta2_on_gp02.950010

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
beta2_on_gp 7DHI-β2-Salbutamol-Gs/β1/γ2
6NI3-β2-BI167107-Gs/β1/γ2
beta2_off 2RH1-β2-S-Carazolol
6PS3-β2-S-Carvedilol
6PS5-β2-S-Propranolol
3D4S-β2-Timolol
3NY8-β2-ICI118-551
3NY9-β2-ICI118-551
6PRZ-β2-S-Alprenolol
Network Difference
Value beta2_on_gp beta2_off
Imin 3.08 3.72571
Number of Linked Nodes 889 273
Number of Specific Nodes 628 (70.64%) 12  (4.40%)
Number of Shared Nodes 261 (29.36%) 261  (95.60%)
Number of Links 1020 302
Number of Specific Links 837 (82.06%) 119  (39.40%)
Number of Shared Links 183 (17.94%) 183  (60.60%)
Number of Hubs 140 33
Number of Specific Hubs 120 (85.71%) 13  (39.39%)
Number of Shared Hubs 20 (14.29%) 20  (60.61%)
Average % Shared Neighbours (Jaccard) 15.10
Average % Shared Neighbours (Otsuka) 17.82
Average % Shared Neighbours (Overlap Coefficient) 20.56
Average % Shared Cliques (k3-6) 51.62
Graphlets Similarity 0.671591
Paths Difference
Value beta2_on_gp beta2_off
Number Of Nodes in MetaPath 91 80
Specific Nodes in MetaPath 72 (79.12%) 61  (76.25%)
Shared Nodes in MetaPath 261 (29.36%) 261  (29.36%)
Number Of Links MetaPath 94 77
Specific Links in MetaPath 84 (89.36%) 67  (87.01%)
Shared Links in MetaPath 183 (17.94%) 183  (17.94%)
Number of Shortest Paths 1670576 42216
Length Of Smallest Path 3 3
Average Path Length 34.678 15.0443
Length of Longest Path 66 35
Minimum Path Strength 0.77 0.729286
Average Path Strength 5.90764 6.41064
Maximum Path Strength 21.74 26.2843
Minimum Path Correlation 0.7 0.704286
Average Path Correlation 0.978584 0.923459
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 1.78571 3.33333
Average % Of Corr. Nodes 36.4356 44.5059
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 44.6465 36.996
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

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