psnGPCR

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Orange: nodes, hubs and links specific of blt1_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of blt1_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	blt1_off Int. Strength	blt1_on Int. Strength	blt1_off Hub1?	blt1_on Hub1?	blt1_off Hub2?	blt1_on Hub2?	ConSurf1	ConSurf2
1	1x27	1x30	blt1_off	6.02	0	No	No	No	No	3	3
2	1x39	2x57	blt1_off	3.15	0	No	No	No	No	7	7
3	1x43	2x58	blt1_off	4.93	0	No	No	No	No	6	9
4	1x49	7x50	blt1_off	4.06	0	No	No	No	No	7	9
5	1x51	2x51	blt1_off	6.01	0	No	No	No	No	3	7
6	1x52	1x55	blt1_off	4.01	0	No	Yes	No	No	6	3
7	1x53	7x53	blt1_off	3.79	0	No	No	Yes	Yes	8	9
8	1x54	2x44	blt1_off	4.47	0	No	No	Yes	No	7	6
9	1x58	1x59	blt1_off	4.23	0	No	No	No	No	3	4
10	1x60	I4.G309	blt1_off	4.5	0	No	No	Yes	No	5	7
11	I1x48	I4.L313	blt1_off	4.24	0	No	No	No	No	6	6
12	I1x50	I4.T308	blt1_off	9.01	0	No	No	No	No	6	4
13	4x43	I1x51	blt1_off	6.4	0	No	No	No	No	4	6
14	2x37	I4.E314	blt1_off	8.62	0	No	No	No	No	7	6
15	2x38	4x42	blt1_off	3.39	0	No	No	No	No	6	7
16	2x39	I4.E314	blt1_off	5.64	0	No	No	No	No	7	6
17	2x39	I4.F317	blt1_off	6.49	0	No	No	No	No	7	7
18	2x41	4x43	blt1_off	6.07	0	No	No	No	No	6	4
19	2x42	3x42	blt1_off	5.65	0	No	No	No	No	7	7
20	2x43	7x53	blt1_off	5.05	0	No	Yes	Yes	Yes	7	9
21	2x43	I4.F317	blt1_off	3.93	0	No	Yes	No	No	7	7
22	2x44	2x48	blt1_off	4.15	0	Yes	No	No	No	6	5
23	2x53	3x32	blt1_off	3.42	0	Yes	No	Yes	No	6	6
24	2x53	Lig	blt1_off	3.51	0	Yes	No	Yes	Yes	6	0
25	2x54	7x46	blt1_off	6.01	0	No	No	No	No	5	9
26	2x56	2x60	blt1_off	5.19	0	No	No	Yes	No	6	6
27	2x60	3x28	blt1_off	4.19	0	Yes	No	No	No	6	5
28	2x60	7x42	blt1_off	4.29	0	Yes	No	Yes	No	6	6
29	2x65	2x66	blt1_off	3.03	0	No	No	No	No	4	3
30	3x28	E1x50	blt1_off	3.92	0	No	No	Yes	Yes	5	8
31	E1x50	E2.V158	blt1_off	4.9	0	Yes	Yes	No	No	8	4
32	3x25	E2.V158	blt1_off	3.42	0	No	No	No	No	9	4
33	3x29	Lig	blt1_off	22.73	0	No	Yes	Yes	Yes	6	0
34	3x30	4x54	blt1_off	7.22	0	Yes	No	No	No	5	3
35	3x30	4x59	blt1_off	4.99	0	Yes	No	No	No	5	4
36	3x30	4x61	blt1_off	3.79	0	Yes	No	No	No	5	4
37	3x32	Lig	blt1_off	7.48	0	Yes	No	Yes	Yes	6	0
38	3x36	5x43	blt1_off	6.77	0	No	No	Yes	No	7	5
39	3x36	6x52	blt1_off	3.94	0	No	No	Yes	Yes	7	8
40	3x37	5x461	blt1_off	4.35	0	Yes	Yes	No	No	7	5
41	3x39	6x44	blt1_off	3.96	0	No	No	Yes	No	9	9
42	3x40	3x41	blt1_off	3.68	0	No	No	Yes	No	8	5
43	3x40	6x44	blt1_off	5.24	0	No	No	Yes	No	8	9
44	3x41	4x49	blt1_off	3.52	0	Yes	No	No	No	5	6
45	3x41	4x52	blt1_off	4.56	0	Yes	No	No	No	5	4
46	3x41	5x49	blt1_off	4.56	0	Yes	No	No	No	5	5
47	3x43	3x44	blt1_off	3.04	0	No	No	Yes	No	8	7
48	3x43	5x51	blt1_off	3.77	0	No	No	Yes	Yes	8	6
49	3x43	6x41	blt1_off	4.42	0	No	No	Yes	No	8	8
50	3x44	3x47	blt1_off	3.2	0	Yes	No	No	No	7	9
51	3x44	5x54	blt1_off	4.76	0	Yes	No	No	No	7	8
52	3x46	6x37	blt1_off	3.04	0	No	No	Yes	No	8	7
53	3x50	5x61	blt1_off	3.76	0	Yes	No	No	No	9	8
54	3x50	6x37	blt1_off	5.23	0	Yes	No	Yes	No	9	7
55	3x51	3x55	blt1_off	8.01	0	No	No	No	No	8	7
56	3x51	5x60	blt1_off	8.05	0	No	No	No	No	8	3
57	3x52	I2x52	blt1_off	5.96	0	No	No	No	No	5	5
58	3x53	I2x53	blt1_off	3.42	0	No	No	No	No	7	5
59	4x61	4x65	blt1_off	3.92	0	No	No	Yes	No	4	5
60	4x64	E2.P173	blt1_off	4.17	0	Yes	No	No	No	4	4
61	4x65	Lig	blt1_off	12.17	0	Yes	No	Yes	Yes	5	0
62	E2.P160	E2.S166	blt1_off	3.56	0	No	No	No	No	1	4
63	E2x51	Lig	blt1_off	5.02	0	No	Yes	Yes	Yes	3	0
64	E2x52	Lig	blt1_off	7.74	0	Yes	No	Yes	Yes	4	0
65	5x32	5x35	blt1_off	6.97	0	No	No	No	No	4	2
66	5x33	E3.A254	blt1_off	4.53	0	No	No	No	No	3	2
67	5x36	6x58	blt1_off	9.3	0	Yes	No	Yes	Yes	4	3
68	5x38	5x42	blt1_off	5.36	0	No	No	No	No	3	3
69	5x40	7x34	blt1_off	6.07	0	No	No	Yes	No	4	4
70	5x43	6x51	blt1_off	6.73	0	Yes	No	Yes	Yes	5	6
71	5x43	6x52	blt1_off	3.69	0	Yes	No	Yes	Yes	5	8
72	5x54	6x41	blt1_off	3.07	0	No	No	Yes	No	8	8
73	5x58	6x38	blt1_off	5.05	0	Yes	Yes	No	No	8	5
74	5x58	6x41	blt1_off	4.84	0	Yes	Yes	Yes	No	8	8
75	6x34	I4.Q318	blt1_off	4.93	0	No	No	No	No	6	4
76	6x35	6x38	blt1_off	5.23	0	No	No	No	No	6	5
77	6x36	6x40	blt1_off	4.28	0	No	No	No	No	7	7
78	6x36	I4.F317	blt1_off	7.31	0	No	No	No	No	7	7
79	6x37	6x41	blt1_off	3.07	0	Yes	No	Yes	No	7	8
80	6x40	7x49	blt1_off	7.08	0	No	No	No	No	7	9
81	6x43	7x48	blt1_off	6.35	0	No	No	No	No	6	6
82	6x47	7x40	blt1_off	4.87	0	No	No	No	No	7	8
83	6x47	7x43	blt1_off	7.31	0	No	No	No	No	7	5
84	6x48	6x51	blt1_off	6.75	0	Yes	Yes	Yes	Yes	9	6
85	6x51	Lig	blt1_off	4.84	0	Yes	Yes	Yes	Yes	6	0
86	6x55	7x34	blt1_off	12.05	0	Yes	No	Yes	No	6	4
87	6x58	6x61	blt1_off	5.82	0	Yes	Yes	Yes	Yes	3	2
88	6x60	6x63	blt1_off	3.42	0	No	No	No	No	3	2
89	6x61	E3.A253	blt1_off	4.15	0	Yes	Yes	No	No	2	3
90	7x31	E3.G255	blt1_off	3.71	0	No	No	No	No	3	2
91	E3.G257	E3.L256	blt1_off	3.42	0	No	No	No	No	8	4
92	7x27	7x30	blt1_off	3.42	0	No	No	Yes	No	3	5
93	7x34	7x38	blt1_off	3.76	0	Yes	No	No	No	4	5
94	7x41	Lig	blt1_off	3.71	0	No	No	Yes	Yes	8	0
95	7x48	7x52	blt1_off	4.47	0	No	No	No	Yes	6	8
96	7x49	7x53	blt1_off	4.65	0	No	No	Yes	Yes	9	9
97	7x61	I4.V315	blt1_off	4.47	0	No	No	No	No	7	6
98	7x62	I4.V298	blt1_off	9.15	0	No	Yes	No	No	6	5
99	7x62	I4.V301	blt1_off	17	0	No	Yes	No	No	6	3
100	I4.F300	I4.L304	blt1_off	4.87	0	No	No	No	No	5	4
101	I4.E311	I4.L304	blt1_off	3.98	0	No	No	No	No	3	4
102	I4.L304	I4.V315	blt1_off	4.47	0	No	No	No	No	4	6
103	I4.F312	I4.L305	blt1_off	15.83	0	No	No	No	No	4	7
104	I4.E311	I4.G307	blt1_off	3.27	0	No	No	No	No	3	5
105	I4.A310	I4.E314	blt1_off	3.02	0	No	No	No	No	6	6
106	I4.F312	I4.L316	blt1_off	10.96	0	No	No	No	No	4	5
107	3x50	6x34	blt1_off	3	0	Yes	No	No	No	9	6
108	7x43	7x47	blt1_off	3	0	No	No	Yes	No	5	7
109	7x58	7x62	blt1_off	3	0	No	Yes	No	Yes	4	6
110	7x26	7x30	blt1_off	2.98	0	No	No	Yes	No	2	5
111	I4.L305	I4.V301	blt1_off	2.98	0	No	No	No	No	7	3
112	1x36	2x61	blt1_off	2.85	0	No	No	No	No	5	7
113	5x41	6x56	blt1_off	2.85	0	No	No	No	No	4	5
114	2x42	4x46	blt1_off	2.83	0	No	No	Yes	No	7	7
115	1x47	2x55	blt1_off	2.77	0	No	No	No	No	5	5
116	4x40	4x44	blt1_off	2.77	0	No	No	No	No	5	3
117	4x55	4x56	blt1_off	2.77	0	No	No	No	No	4	4
118	5x67	I3.R215	blt1_off	2.77	0	No	No	Yes	No	4	5
119	7x61	I4.L316	blt1_off	2.77	0	No	No	No	No	7	5
120	3x37	4x57	blt1_off	2.67	0	Yes	Yes	No	No	7	7
121	I2x53	I2x57	blt1_off	2.64	0	No	No	Yes	No	5	7
122	1x55	1x56	blt1_off	2.47	0	No	No	No	No	3	7
123	6x39	7x55	blt1_off	2.44	0	No	No	No	Yes	5	7
124	3x26	4x62	blt1_off	2.43	0	No	No	No	No	7	4
125	6x32	I4.Q318	blt1_off	2.34	0	No	No	No	No	7	4
126	E2.R171	E2x51	blt1_off	2.14	0	No	No	No	Yes	4	3
127	7x27	E3.G257	blt1_off	2.11	0	No	No	No	No	3	8
128	5x34	5x37	blt1_off	1.95	0	No	No	No	No	3	3
129	6x59	6x60	blt1_off	1.95	0	No	No	No	No	4	3
130	6x64	E3.G251	blt1_off	1.95	0	No	No	No	No	4	2
131	7x56	7x57	blt1_off	1.95	0	No	No	No	No	5	7
132	I4.G309	I4.T308	blt1_off	1.82	0	Yes	No	No	No	7	4
133	1x35	7x39	blt1_off	1.79	0	No	No	No	No	5	4
134	I1x48	I4.G309	blt1_off	1.75	0	No	No	Yes	No	6	7
135	2x37	2x40	blt1_off	1.71	0	No	No	No	No	7	7
136	5x62	5x65	blt1_off	1.71	0	No	No	Yes	No	5	8
137	6x54	7x33	blt1_off	1.7	0	No	No	No	No	4	5
138	4x38	4x40	blt1_off	1.68	0	No	No	No	No	6	5
139	E3.G251	E3.Q252	blt1_off	1.64	0	No	No	No	No	2	3
140	I4.E311	I4.G309	blt1_off	1.64	0	No	No	Yes	No	3	7
141	1x45	7x51	blt1_off	1.6	0	No	No	No	No	5	6
142	6x53	6x54	blt1_off	1.6	0	No	No	No	No	6	4
143	7x48	7x51	blt1_off	1.6	0	No	No	No	No	6	6
144	5x44	5x48	blt1_off	1.58	0	No	No	No	No	5	4
145	3x54	5x61	blt1_off	1.54	0	No	No	No	No	8	8
146	4x41	4x45	blt1_off	1.52	0	No	No	No	No	3	5
147	3x24	E1x52	blt1_off	1.51	0	No	No	Yes	Yes	5	7
148	I4.F300	I4.G297	blt1_off	1.51	0	No	No	No	No	5	4
149	5x65	6x30	blt1_off	1.5	0	Yes	No	No	No	8	6
150	1x41	7x43	blt1_off	1.49	0	No	No	No	No	5	5
151	3x27	3x31	blt1_off	1.49	0	No	No	No	No	4	5
152	4x45	4x46	blt1_off	1.49	0	No	No	Yes	No	5	7
153	4x51	4x55	blt1_off	1.49	0	No	No	No	No	4	4
154	5x45	5x48	blt1_off	1.49	0	No	No	No	No	5	4
155	5x45	5x49	blt1_off	1.49	0	No	No	No	No	5	5
156	7x36	7x40	blt1_off	1.49	0	No	No	No	No	6	8
157	1x36	1x37	blt1_off	1.47	0	No	No	No	No	5	6
158	1x31	1x34	blt1_off	1.43	0	No	No	No	No	2	5
159	1x33	1x36	blt1_off	1.43	0	No	No	No	No	5	5
160	1x34	1x37	blt1_off	1.43	0	No	No	No	No	5	6
161	I4.E306	I4.K303	blt1_off	1.35	0	No	No	No	No	7	3
162	6x33	6x35	blt1_off	1.29	0	No	No	No	No	7	6
163	I2x51	I2x55	blt1_off	1.24	0	No	No	No	No	5	4
164	I3.F213	I3.R214	blt1_off	1.07	0	No	No	No	No	4	3
165	6x31	I3.R215	blt1_off	1.07	0	No	No	Yes	No	5	5
166	1x31	7x32	Shared	4.28	2.85	No	No	No	No	2	2
167	1x31	7x36	Shared	3.07	4.61	No	No	No	No	2	6
168	1x32	2x64	Shared	6.01	1.5	No	No	No	Yes	4	3
169	1x38	7x39	Shared	3.15	3.15	No	No	No	No	5	4
170	1x38	7x40	Shared	4.15	1.38	No	No	No	No	5	8
171	1x39	2x61	Shared	5.54	5.54	No	No	No	No	7	7
172	1x39	7x42	Shared	10.96	4.87	No	No	Yes	No	7	6
173	1x42	7x47	Shared	3.42	1.71	No	No	Yes	No	7	7
174	1x43	2x57	Shared	3.15	4.73	No	No	No	No	6	7
175	1x45	7x47	Shared	3.23	6.46	No	No	Yes	No	5	7
176	1x50	2x50	Shared	6.73	12.12	No	Yes	No	Yes	9	9
177	1x50	7x50	Shared	13.03	8.15	No	Yes	No	No	9	9
178	1x53	2x47	Shared	3.39	3.39	No	No	No	No	8	8
179	1x55	1x59	Shared	8.12	4.64	No	No	No	No	3	4
180	1x57	2x43	Shared	3.07	3.07	No	Yes	No	Yes	7	7
181	1x57	2x44	Shared	8.56	7.14	No	Yes	Yes	No	7	6
182	1x58	2x44	Shared	4.15	4.15	No	No	Yes	No	3	6
183	2x40	I1x48	Shared	3.22	1.61	No	No	No	No	7	6
184	2x41	I1x51	Shared	6.07	2.43	No	No	No	No	6	6
185	2x38	I2x57	Shared	13.08	11.77	No	No	Yes	No	6	7
186	2x39	I2x57	Shared	5.17	3.88	No	No	Yes	No	7	7
187	2x41	4x46	Shared	5.54	1.38	No	No	Yes	No	6	7
188	2x42	3x46	Shared	4.33	5.78	No	No	No	No	7	8
189	2x45	4x46	Shared	10.98	8.24	No	No	Yes	No	9	7
190	2x45	4x50	Shared	7.91	4.52	No	No	No	No	9	9
191	2x46	3x42	Shared	6.92	2.77	No	Yes	No	No	9	7
192	2x50	7x46	Shared	8.83	5.89	No	Yes	No	No	9	9
193	2x50	7x49	Shared	6.73	6.73	No	Yes	No	No	9	9
194	2x53	3x35	Shared	6.46	4.85	Yes	No	No	No	6	8
195	2x53	7x42	Shared	3.93	2.62	Yes	No	Yes	No	6	6
196	2x53	7x46	Shared	3.23	6.46	Yes	No	No	No	6	9
197	2x56	3x32	Shared	3.38	6.76	No	No	Yes	No	6	6
198	2x59	E1x52	Shared	6.43	7.5	No	No	Yes	Yes	6	7
199	2x59	3x28	Shared	5.59	5.59	No	No	No	No	6	5
200	2x60	3x29	Shared	9.05	6.79	Yes	No	No	Yes	6	6
201	2x60	Lig	Shared	15.79	18.93	Yes	No	Yes	Yes	6	0
202	2x62	2x66	Shared	23.49	14.84	No	No	No	No	3	3
203	2x62	E1x51	Shared	5.58	5.58	No	No	No	No	3	4
204	2x62	E1x52	Shared	7.92	6.79	No	No	Yes	Yes	3	7
205	2x63	E1x50	Shared	6.01	5.01	No	No	Yes	Yes	5	8
206	2x64	Lig	Shared	5.71	11.18	No	Yes	Yes	Yes	3	0
207	E1x49	E2.S166	Shared	3.2	1.6	No	No	No	No	4	4
208	E1x50	E1x52	Shared	18.04	5.01	Yes	Yes	Yes	Yes	8	7
209	3x25	E1x50	Shared	6.53	9.14	No	No	Yes	Yes	9	8
210	E1x50	E2x50	Shared	3.92	15.67	Yes	Yes	No	No	8	9
211	E1x51	E1x52	Shared	7.93	2.64	No	No	Yes	Yes	4	7
212	3x22	3x26	Shared	15.79	17.01	No	No	No	No	2	7
213	3x25	E2x50	Shared	7.28	7.28	No	No	No	No	9	9
214	3x29	4x65	Shared	29.34	14.67	No	Yes	Yes	No	6	5
215	3x30	3x34	Shared	5.05	3.79	Yes	No	No	Yes	5	5
216	3x30	4x62	Shared	16.41	10.55	Yes	No	No	No	5	4
217	3x34	4x54	Shared	3.93	6.55	No	Yes	No	No	5	3
218	3x36	6x48	Shared	11.63	3.49	No	No	Yes	Yes	7	9
219	3x37	4x56	Shared	9.38	10.55	Yes	Yes	No	No	7	4
220	3x37	5x46	Shared	6.24	3.75	Yes	Yes	No	Yes	7	5
221	3x38	4x50	Shared	3.89	5.19	No	No	No	No	6	9
222	3x38	4x53	Shared	3.42	3.42	No	No	No	No	6	8
223	3x40	5x50	Shared	8.84	3.53	No	No	Yes	Yes	8	9
224	3x41	3x44	Shared	7.28	3.64	Yes	No	Yes	No	5	7
225	3x41	5x50	Shared	20.27	6.76	Yes	No	Yes	Yes	5	9
226	3x42	4x49	Shared	7.14	4.28	No	No	No	No	7	6
227	3x44	5x50	Shared	3.5	5.25	Yes	No	Yes	Yes	7	9
228	3x44	5x53	Shared	4.56	4.56	Yes	No	No	No	7	6
229	3x47	5x54	Shared	9.7	8.08	No	No	No	No	9	8
230	3x47	5x57	Shared	3.26	3.26	No	No	No	No	9	6
231	3x48	5x53	Shared	4.28	4.28	No	No	No	No	6	6
232	3x49	I2x57	Shared	17.87	8.34	No	No	Yes	No	8	7
233	3x50	5x58	Shared	7.2	7.2	Yes	No	Yes	Yes	9	8
234	3x55	5x64	Shared	4.15	2.77	No	No	No	Yes	7	5
235	3x56	I2x52	Shared	6.54	2.62	No	No	No	No	7	5
236	4x39	4x43	Shared	6.19	3.71	No	No	No	No	4	4
237	4x59	4x60	Shared	3.5	3.5	No	No	No	No	4	8
238	4x60	5x39	Shared	3.05	3.05	No	No	Yes	Yes	8	5
239	4x64	E2.Y172	Shared	13.9	16.88	Yes	No	Yes	Yes	4	4
240	4x64	5x35	Shared	7.62	6.53	Yes	No	No	No	4	2
241	4x64	5x39	Shared	7.62	4.36	Yes	No	Yes	Yes	4	5
242	4x65	E2x52	Shared	18.74	15.85	Yes	No	Yes	No	5	4
243	E2.T157	E2.V159	Shared	3.17	1.59	No	No	No	No	4	3
244	E2.K162	E2.W161	Shared	19.73	11.6	No	No	No	No	1	2
245	E2.M165	E2.W161	Shared	3.49	3.49	No	Yes	No	No	3	2
246	E2.L167	E2.W161	Shared	6.83	4.56	No	No	No	No	3	2
247	E2.N164	E2.T163	Shared	4.39	2.92	No	No	No	No	5	3
248	E2x51	E2x52	Shared	13	4.33	No	Yes	Yes	No	3	4
249	E2.Y172	E2x52	Shared	8.34	8.34	Yes	Yes	Yes	No	4	4
250	5x36	E2.Y172	Shared	13.38	13.38	Yes	No	Yes	Yes	4	4
251	5x39	E2.Y172	Shared	6.53	11.98	Yes	Yes	Yes	Yes	5	4
252	5x35	E2.P173	Shared	13.73	4.58	No	No	No	No	2	4
253	5x33	5x36	Shared	11.63	5.82	No	No	Yes	No	3	4
254	5x33	6x62	Shared	3.02	1.51	No	No	No	No	3	3
255	5x36	E3.A254	Shared	5.53	4.15	Yes	No	No	No	4	2
256	5x37	6x63	Shared	3.15	4.73	No	No	No	No	3	2
257	5x39	5x43	Shared	4.92	7.39	Yes	Yes	Yes	No	5	5
258	5x40	6x55	Shared	5.49	2.75	No	No	Yes	No	4	6
259	5x42	5x46	Shared	15.56	7.78	No	No	No	Yes	3	5
260	5x43	6x55	Shared	6.57	2.63	Yes	No	Yes	No	5	6
261	5x44	6x56	Shared	4.73	3.15	No	No	No	No	5	5
262	5x47	5x51	Shared	18.22	6.43	Yes	Yes	Yes	Yes	8	6
263	5x47	6x44	Shared	3.22	4.29	Yes	Yes	Yes	No	8	9
264	5x47	6x49	Shared	8.53	3.65	Yes	Yes	No	No	8	6
265	5x47	6x52	Shared	12.44	9.05	Yes	Yes	Yes	Yes	8	8
266	5x49	5x50	Shared	3.28	1.64	No	No	Yes	Yes	5	9
267	5x51	6x44	Shared	3.22	5.36	Yes	Yes	Yes	No	6	9
268	5x58	6x37	Shared	3.79	8.83	Yes	Yes	Yes	No	8	7
269	5x60	5x64	Shared	4.76	13.1	No	No	No	Yes	3	5
270	5x65	I3.R215	Shared	3.64	2.43	Yes	No	Yes	No	8	5
271	I3.F213	I3.R215	Shared	21.38	4.28	No	No	Yes	No	4	5
272	6x39	7x52	Shared	6.92	1.38	No	No	No	Yes	5	8
273	6x40	7x53	Shared	3.63	4.84	No	No	Yes	Yes	7	9
274	6x43	7x52	Shared	7.37	2.95	No	No	No	Yes	6	8
275	6x44	6x48	Shared	21.05	5.01	Yes	No	Yes	Yes	9	9
276	6x47	7x45	Shared	7.93	5.28	No	No	No	No	7	9
277	6x48	6x52	Shared	5.29	3.17	Yes	Yes	Yes	Yes	9	8
278	6x48	7x41	Shared	5.19	5.19	Yes	Yes	No	No	9	8
279	6x48	7x45	Shared	7.41	7.41	Yes	Yes	No	No	9	9
280	6x48	Lig	Shared	8.05	3.54	Yes	Yes	Yes	Yes	9	0
281	6x49	6x50	Shared	3.28	3.28	No	No	No	No	6	9
282	6x50	7x37	Shared	4.93	3.28	No	No	No	No	9	7
283	6x51	6x52	Shared	8.71	5.44	Yes	Yes	Yes	Yes	6	8
284	6x51	6x55	Shared	11.63	15.12	Yes	Yes	Yes	No	6	6
285	6x51	7x34	Shared	3.09	6.17	Yes	Yes	Yes	No	6	4
286	6x54	7x37	Shared	4.47	2.98	No	No	No	No	4	7
287	6x57	7x30	Shared	4.73	3.15	No	No	Yes	No	4	5
288	6x58	7x31	Shared	4.31	1.44	Yes	Yes	No	No	3	3
289	6x58	7x34	Shared	12.79	3.49	Yes	Yes	Yes	No	3	4
290	6x61	7x27	Shared	4.5	3	Yes	Yes	No	No	2	3
291	6x61	7x30	Shared	6.07	2.43	Yes	Yes	Yes	No	2	5
292	7x35	Lig	Shared	5.66	6.83	No	No	Yes	Yes	4	0
293	7x38	Lig	Shared	15.14	6.21	No	No	Yes	Yes	5	0
294	7x42	Lig	Shared	9.33	3.03	Yes	No	Yes	Yes	6	0
295	4x38	4x41	Shared	3.01	1.51	No	No	No	No	6	3
296	3x52	I2x53	Shared	3	3	No	No	No	No	5	5
297	I2x52	I2x56	Shared	2.98	1.49	No	No	No	No	5	4
298	5x44	6x52	Shared	2.93	1.46	No	No	Yes	Yes	5	8
299	I2x55	I2x56	Shared	2.82	1.41	No	No	No	No	4	4
300	3x21	E1x50	Shared	2.81	2.81	No	No	Yes	Yes	8	8
301	4x52	4x56	Shared	2.77	6.92	No	No	No	No	4	4
302	5x51	6x45	Shared	2.77	2.77	Yes	Yes	No	No	6	5
303	1x50	2x51	Shared	2.75	5.49	No	Yes	No	No	9	7
304	3x30	4x57	Shared	2.67	2.67	Yes	No	No	No	5	7
305	2x49	4x50	Shared	2.59	2.59	No	No	No	No	8	9
306	E2.R171	E2.T157	Shared	2.59	2.59	No	No	No	No	4	4
307	3x51	5x57	Shared	2.54	6.52	No	No	No	No	8	6
308	2x63	E2.L167	Shared	2.44	2.44	No	No	No	No	5	3
309	7x57	7x58	Shared	2.11	2.11	No	No	No	Yes	7	4
310	7x58	7x59	Shared	2.11	2.11	No	Yes	No	No	4	6
311	1x48	1x49	Shared	2.03	2.03	No	No	No	No	5	7
312	3x32	3x33	Shared	1.96	1.96	Yes	No	No	No	6	4
313	1x46	7x47	Shared	1.86	3.71	No	No	Yes	No	8	7
314	5x32	5x34	Shared	1.86	1.86	No	No	No	No	4	3
315	E2.P160	E2.V159	Shared	1.77	3.53	No	No	No	No	1	3
316	1x47	1x48	Shared	1.64	3.28	No	No	No	No	5	5
317	3x45	4x49	Shared	1.62	1.62	No	No	No	No	6	6
318	2x56	3x31	Shared	1.59	3.17	No	No	No	No	6	5
319	3x56	I2x50	Shared	1.44	1.44	No	No	No	No	7	8
320	5x61	5x65	Shared	1.43	2.85	No	No	Yes	No	8	8
321	1x29	1x30	blt1_on	0	8.16	No	No	No	No	4	3
322	1x33	1x37	blt1_on	0	2.85	No	No	No	No	5	6
323	1x34	7x36	blt1_on	0	4.47	No	No	No	No	5	6
324	1x35	2x64	blt1_on	0	3.15	No	No	No	Yes	5	3
325	1x36	2x64	blt1_on	0	2.85	No	No	No	Yes	5	3
326	1x39	7x39	blt1_on	0	3.15	No	No	No	No	7	4
327	1x42	7x43	blt1_on	0	3.15	No	No	No	No	7	5
328	1x52	1x56	blt1_on	0	7.93	No	Yes	No	No	6	7
329	1x52	7x55	blt1_on	0	4.29	No	Yes	No	Yes	6	7
330	1x52	7x62	blt1_on	0	3.21	No	Yes	No	Yes	6	6
331	1x53	7x55	blt1_on	0	2.62	No	No	No	Yes	8	7
332	1x55	1x60	blt1_on	0	6	No	No	No	No	3	5
333	1x56	1x60	blt1_on	0	2.64	No	No	No	No	7	5
334	1x56	7x62	blt1_on	0	5.27	No	No	No	Yes	7	6
335	1x57	2x40	blt1_on	0	3.25	No	Yes	No	No	7	7
336	1x57	7x62	blt1_on	0	6.26	No	Yes	No	Yes	7	6
337	I1x49	I1x50	blt1_on	0	4.07	No	No	No	No	6	6
338	2x43	7x61	blt1_on	0	4.47	No	Yes	No	No	7	7
339	2x46	3x43	blt1_on	0	4.28	No	Yes	No	No	9	8
340	2x46	3x46	blt1_on	0	5.65	No	Yes	No	No	9	8
341	2x46	7x49	blt1_on	0	6.87	No	Yes	No	No	9	9
342	2x46	7x53	blt1_on	0	3.52	No	Yes	Yes	Yes	9	9
343	2x50	3x39	blt1_on	0	2.94	No	Yes	No	No	9	9
344	2x50	7x50	blt1_on	0	3.22	No	Yes	No	No	9	9
345	2x52	3x35	blt1_on	0	3.42	No	No	No	No	6	8
346	E1x49	E2.M165	blt1_on	0	3.01	No	No	No	Yes	4	3
347	3x22	E2.V158	blt1_on	0	5.96	No	No	No	No	2	4
348	3x25	3x29	blt1_on	0	4.42	No	No	No	Yes	9	6
349	3x29	4x61	blt1_on	0	4.15	No	Yes	No	No	6	4
350	3x34	4x53	blt1_on	0	4.85	No	Yes	No	No	5	8
351	3x34	4x57	blt1_on	0	3.39	No	Yes	No	No	5	7
352	3x36	Lig	blt1_on	0	5.27	No	No	Yes	Yes	7	0
353	3x37	4x53	blt1_on	0	2.54	Yes	Yes	No	No	7	8
354	3x37	Lig	blt1_on	0	4.37	Yes	Yes	Yes	Yes	7	0
355	3x43	7x53	blt1_on	0	6.04	No	No	Yes	Yes	8	9
356	3x46	7x53	blt1_on	0	3.59	No	No	Yes	Yes	8	9
357	3x47	5x58	blt1_on	0	3.82	No	No	Yes	Yes	9	8
358	3x50	7x53	blt1_on	0	8.23	Yes	No	Yes	Yes	9	9
359	3x51	5x61	blt1_on	0	3.1	No	No	No	No	8	8
360	I2x51	I2x54	blt1_on	0	3.51	No	No	No	No	5	5
361	4x56	5x46	blt1_on	0	2.95	No	No	No	Yes	4	5
362	4x61	Lig	blt1_on	0	2.78	No	No	Yes	Yes	4	0
363	4x65	E2x51	blt1_on	0	4.28	Yes	No	No	Yes	5	3
364	E2.V158	E2x50	blt1_on	0	3.42	No	No	No	No	4	9
365	E2.V159	E2x51	blt1_on	0	6.55	No	No	No	Yes	3	3
366	E2.K162	E2.M165	blt1_on	0	2.88	No	No	No	Yes	1	3
367	5x40	6x58	blt1_on	0	2.65	No	No	Yes	Yes	4	3
368	5x40	6x59	blt1_on	0	3.15	No	No	No	No	4	4
369	5x43	Lig	blt1_on	0	8.24	Yes	No	Yes	Yes	5	0
370	5x45	5x46	blt1_on	0	3.17	No	No	No	Yes	5	5
371	5x51	5x55	blt1_on	0	3.93	Yes	Yes	No	No	6	5
372	5x55	6x41	blt1_on	0	3.07	No	No	Yes	No	5	8
373	5x58	6x40	blt1_on	0	3.63	Yes	Yes	No	No	8	7
374	5x60	5x63	blt1_on	0	4.76	No	No	No	No	3	5
375	5x61	5x62	blt1_on	0	3.53	No	No	No	No	8	5
376	5x63	5x64	blt1_on	0	6.4	No	No	No	Yes	5	5
377	5x66	I3.R215	blt1_on	0	3.5	No	No	Yes	No	5	5
378	5x68	I3.F213	blt1_on	0	6.41	No	No	No	No	5	4
379	6x31	6x32	blt1_on	0	21.32	No	No	No	No	5	7
380	6x31	6x33	blt1_on	0	2.59	No	No	No	No	5	7
381	6x32	7x58	blt1_on	0	4.5	No	No	No	Yes	7	4
382	6x36	7x56	blt1_on	0	3.15	No	No	No	No	7	5
383	6x38	6x42	blt1_on	0	2.98	No	No	No	No	5	5
384	6x40	7x52	blt1_on	0	5.71	No	No	No	Yes	7	8
385	6x43	6x47	blt1_on	0	2.59	No	No	No	No	6	7
386	6x47	7x48	blt1_on	0	2.62	No	No	No	No	7	6
387	6x49	6x53	blt1_on	0	2.98	No	No	No	No	6	6
388	6x51	7x38	blt1_on	0	4.84	Yes	Yes	No	No	6	5
389	6x54	6x58	blt1_on	0	2.85	No	No	Yes	Yes	4	3
390	6x54	7x34	blt1_on	0	2.62	No	No	Yes	No	4	4
391	6x58	7x30	blt1_on	0	3.98	Yes	Yes	Yes	No	3	5
392	6x61	E3.Q252	blt1_on	0	14.02	Yes	Yes	No	No	2	3
393	6x61	7x26	blt1_on	0	7.85	Yes	Yes	No	No	2	2
394	E3.L256	E3.Q252	blt1_on	0	3.99	No	No	No	No	4	3
395	E3.A253	E3.L256	blt1_on	0	3.15	No	No	No	No	3	4
396	7x55	7x62	blt1_on	0	5.34	No	Yes	No	Yes	7	6
397	7x55	I4.V298	blt1_on	0	2.62	No	Yes	No	No	7	5
398	7x60	7x63	blt1_on	0	6.01	No	No	No	No	6	3
399	7x61	7x62	blt1_on	0	6.07	No	No	No	Yes	7	6
400	E2.L167	E2x51	blt1_on	0	2.44	No	No	No	Yes	3	3
401	5x47	5x48	blt1_on	0	2.44	Yes	Yes	No	No	8	4
402	1x52	I4.F300	blt1_on	0	2.14	No	Yes	No	No	6	5
403	3x33	Lig	blt1_on	0	2.13	No	No	Yes	Yes	4	0
404	6x32	6x35	blt1_on	0	2.13	No	No	No	No	7	6
405	7x27	E3.G255	blt1_on	0	2.11	No	No	No	No	3	2
406	3x23	3x24	blt1_on	0	1.95	No	No	No	No	1	5
407	4x47	4x48	blt1_on	0	1.95	No	No	No	No	4	3
408	7x64	I4.G297	blt1_on	0	1.95	No	No	No	No	5	4
409	3x37	3x41	blt1_on	0	1.93	Yes	Yes	Yes	No	7	5
410	2x57	2x58	blt1_on	0	1.87	No	No	No	No	7	9
411	7x57	7x63	blt1_on	0	1.86	No	No	No	No	7	3
412	4x48	4x51	blt1_on	0	1.84	No	No	No	No	3	4
413	1x53	7x50	blt1_on	0	1.77	No	No	No	No	8	9
414	1x46	2x54	blt1_on	0	1.71	No	No	No	No	8	5
415	6x36	7x58	blt1_on	0	1.71	No	No	No	Yes	7	4
416	1x46	1x50	blt1_on	0	1.7	No	No	No	Yes	8	9
417	1x54	2x47	blt1_on	0	1.7	No	No	No	No	7	8
418	2x43	7x54	blt1_on	0	1.7	No	Yes	No	No	7	6
419	5x41	6x59	blt1_on	0	1.62	No	No	No	No	4	4
420	1x41	1x45	blt1_on	0	1.6	No	No	No	No	5	5
421	2x39	2x43	blt1_on	0	1.59	No	No	No	Yes	7	7
422	5x461	6x52	blt1_on	0	1.59	No	No	Yes	Yes	5	8
423	2x57	2x61	blt1_on	0	1.58	No	No	No	No	7	7
424	1x36	1x40	blt1_on	0	1.55	No	No	No	No	5	5
425	1x37	1x41	blt1_on	0	1.54	No	No	No	No	6	5
426	4x45	4x49	blt1_on	0	1.54	No	No	No	No	5	6
427	4x38	4x39	blt1_on	0	1.5	No	No	No	No	6	4
428	1x38	7x36	blt1_on	0	1.49	No	No	No	No	5	6
429	1x54	2x48	blt1_on	0	1.49	No	No	No	No	7	5
430	I2x50	I2x51	blt1_on	0	1.44	No	No	No	No	8	5
431	5x32	5x33	blt1_on	0	1.44	No	No	No	No	4	3
432	2x41	4x39	blt1_on	0	1.41	No	No	No	No	6	4
433	4x41	I2x56	blt1_on	0	1.41	No	No	No	No	3	4
434	E2.M165	E2.N164	blt1_on	0	1.4	No	Yes	No	No	3	5
435	1x47	2x51	blt1_on	0	1.38	No	No	No	No	5	7
436	2x40	I1x51	blt1_on	0	1.38	No	No	No	No	7	6
437	6x36	7x52	blt1_on	0	1.38	No	No	No	Yes	7	8
438	7x40	7x43	blt1_on	0	1.38	No	No	No	No	8	5
439	3x54	5x64	blt1_on	0	1.31	No	No	No	Yes	8	5
440	7x29	E3.L258	blt1_on	0	1.21	No	No	No	No	3	4

Orange: nodes, hubs and links specific of blt1_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of blt1_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	blt1_off Avg Int. Strength	blt1_on Avg Int. Strength	blt1_off Num Of Links	blt1_on Num Of Links	ConSurf
1	2x44	blt1_off	5.3325	5.645	4	2	6
2	2x53	blt1_off	4.11	4.64333	5	3	6
3	2x60	blt1_off	7.702	12.86	5	2	6
4	3x30	blt1_off	6.68833	5.67	6	3	5
5	3x32	blt1_off	4.06	4.36	4	2	6
6	3x41	blt1_off	7.31167	4.11	6	3	5
7	3x44	blt1_off	4.39	4.48333	6	3	7
8	3x50	blt1_off	4.7975	7.715	4	2	9
9	I2x57	blt1_off	9.69	7.99667	4	3	7
10	4x46	blt1_off	5.21	4.81	4	2	7
11	4x64	blt1_off	8.3275	9.25667	4	3	4
12	4x65	blt1_off	16.0425	11.6	4	3	5
13	E2x52	blt1_off	11.955	9.50667	4	3	4
14	5x36	blt1_off	9.96	7.78333	4	3	4
15	5x43	blt1_off	5.736	6.08667	5	3	5
16	5x65	blt1_off	2.07	2.64	4	2	8
17	I3.R215	blt1_off	7.215	3.40333	4	3	5
18	6x37	blt1_off	3.7825	8.83	4	1	7
19	6x41	blt1_off	3.85	3.07	4	1	8
20	6x44	blt1_off	7.338	4.88667	5	3	9
21	6x55	blt1_off	8.935	6.83333	4	3	6
22	7x30	blt1_off	4.3	3.18667	4	3	5
23	7x34	blt1_off	7.552	4.09333	5	3	4
24	7x42	blt1_off	7.1275	3.50667	4	3	6
25	7x47	blt1_off	2.8775	3.96	4	3	7
26	I4.G309	blt1_off	2.4275	0	4	0	7
27	E1x50	Shared	6.59	7.528	7	5	8
28	E1x52	Shared	8.366	5.485	5	4	7
29	3x37	Shared	5.66	4.628	4	5	7
30	E2.Y172	Shared	10.5375	12.645	4	4	4
31	5x39	Shared	5.53	6.695	4	4	5
32	5x47	Shared	10.6025	5.172	4	5	8
33	5x50	Shared	8.9725	4.295	4	4	9
34	5x51	Shared	6.995	4.6225	4	4	6
35	5x58	Shared	5.22	5.87	4	4	8
36	6x48	Shared	9.33857	4.635	7	6	9
37	6x51	Shared	6.95833	7.8925	6	4	6
38	6x52	Shared	6.16667	4.142	6	5	8
39	6x58	Shared	8.055	2.882	4	5	3
40	6x61	Shared	5.135	6.825	4	4	2
41	7x53	Shared	4.28	5.244	4	5	9
42	Lig	Shared	9.06286	6.59182	14	11	0
43	1x50	blt1_on	7.50333	6.865	3	4	9
44	1x52	blt1_on	4.01	4.3925	1	4	6
45	1x57	blt1_on	5.815	4.93	2	4	7
46	2x43	blt1_on	4.01667	2.7075	3	4	7
47	2x46	blt1_on	6.92	4.618	1	5	9
48	2x50	blt1_on	7.43	6.18	3	5	9
49	2x64	blt1_on	5.86	4.67	2	4	3
50	3x29	blt1_on	20.3733	7.5075	3	4	6
51	3x34	blt1_on	4.49	4.645	2	4	5
52	E2.M165	blt1_on	3.49	2.695	1	4	3
53	E2x51	blt1_on	6.72	4.4	3	4	3
54	5x46	blt1_on	10.9	4.4125	2	4	5
55	5x64	blt1_on	4.455	5.895	2	4	5
56	7x52	blt1_on	6.25333	2.855	3	4	8
57	7x55	blt1_on	2.44	3.7175	1	4	7
58	7x58	blt1_on	2.40667	2.6075	3	4	4
59	7x62	blt1_on	9.71667	5.23	3	5	6

Orange: nodes, hubs and links specific of blt1_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of blt1_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	blt1_off Recurrence	blt1_on Recurrence	blt1_off Hub1?	blt1_on Hub1?	blt1_off Hub2?	blt1_on Hub2?	ConSurf1	ConSurf2
1	6x47	7x43	blt1_off	13.9865	0	No	No	No	No	7	5
2	7x43	7x47	blt1_off	11.7135	0	No	No	Yes	No	5	7
3	2x53	Lig	blt1_off	87.3169	0	Yes	No	Yes	Yes	6	0
4	7x49	7x53	blt1_off	51.4763	0	No	No	Yes	Yes	9	9
5	2x43	7x53	blt1_off	49.1418	0	No	Yes	Yes	Yes	7	9
6	6x40	7x49	blt1_off	41.1394	0	No	No	No	No	7	9
7	6x36	6x40	blt1_off	40.3339	0	No	No	No	No	7	7
8	6x36	I4.F317	blt1_off	39.5226	0	No	No	No	No	7	7
9	2x39	I4.F317	blt1_off	78.7991	0	No	No	No	No	7	7
10	2x39	I4.E314	blt1_off	53.1342	0	No	No	No	No	7	6
11	2x37	I4.E314	blt1_off	49.3468	0	No	No	No	No	7	6
12	2x37	2x40	blt1_off	47.4458	0	No	No	No	No	7	7
13	2x40	I1x48	blt1_off	45.5331	2.30368	No	No	No	No	7	6
14	I1x48	I4.G309	blt1_off	41.7018	0	No	No	Yes	No	6	7
15	2x43	I4.F317	blt1_off	40.9549	0	No	Yes	No	No	7	7
16	3x40	6x44	blt1_off	38.6907	0	No	No	Yes	No	8	9
17	3x40	3x41	blt1_off	29.3615	0	No	No	Yes	No	8	5
18	3x41	4x49	blt1_off	19.3497	0	Yes	No	No	No	5	6
19	3x42	4x49	blt1_off	17.563	7.46362	No	No	No	No	7	6
20	2x42	3x42	blt1_off	15.8172	0	No	No	No	No	7	7
21	2x42	4x46	blt1_off	16.8688	0	No	No	Yes	No	7	7
22	5x51	6x44	blt1_off	32.9789	7.68153	Yes	Yes	Yes	No	6	9
23	3x43	5x51	blt1_off	40.1875	0	No	No	Yes	Yes	8	6
24	3x43	6x41	blt1_off	33.4856	0	No	No	Yes	No	8	8
25	6x37	6x41	blt1_off	17.6245	0	Yes	No	Yes	No	7	8
26	2x60	3x28	blt1_off	35.1787	0	Yes	No	No	No	6	5
27	2x59	3x28	blt1_off	10.3808	3.85244	No	No	No	No	6	5
28	3x28	E1x50	blt1_off	23.5677	0	No	No	Yes	Yes	5	8
29	4x65	Lig	blt1_off	13.1576	0	Yes	No	Yes	Yes	5	0
30	4x61	4x65	blt1_off	14.795	0	No	No	Yes	No	4	5
31	3x30	4x61	blt1_off	13.7229	0	Yes	No	No	No	5	4
32	3x41	3x44	blt1_off	12.9818	6.52969	Yes	No	Yes	No	5	7
33	3x43	3x44	blt1_off	11.9947	0	No	No	Yes	No	8	7
34	3x44	3x47	blt1_off	15.8319	0	Yes	No	No	No	7	9
35	5x58	6x41	blt1_off	18.2601	0	Yes	Yes	Yes	No	8	8
36	3x50	6x37	blt1_off	15.1113	0	Yes	No	Yes	No	9	7
37	3x50	5x61	blt1_off	21.1511	0	Yes	No	No	No	9	8
38	I2x53	I2x57	blt1_off	18.1869	0	No	No	Yes	No	5	7
39	3x52	I2x53	blt1_off	14.1857	0	No	No	No	No	5	5
40	3x52	I2x52	blt1_off	12.1763	0	No	No	No	No	5	5
41	E2x52	Lig	blt1_off	11.4148	0	Yes	No	Yes	Yes	4	0
42	E2.Y172	E2x52	blt1_off	12.0123	8.06288	Yes	Yes	Yes	No	4	4
43	4x64	5x35	blt1_off	10.577	4.17153	Yes	No	No	No	4	2
44	6x49	6x50	blt1_off	10.8641	5.07432	No	No	No	No	6	9
45	6x58	6x61	blt1_off	14.5723	0	Yes	Yes	Yes	Yes	3	2
46	I4.E311	I4.G309	blt1_off	33.9572	0	No	No	Yes	No	3	7
47	I4.E311	I4.L304	blt1_off	30.0498	0	No	No	No	No	3	4
48	I4.L304	I4.V315	blt1_off	24.1447	0	No	No	No	No	4	6
49	7x61	I4.V315	blt1_off	22.1646	0	No	No	No	No	7	6
50	7x61	I4.L316	blt1_off	20.1787	0	No	No	No	No	7	5
51	I4.F312	I4.L316	blt1_off	18.1869	0	No	No	No	No	4	5
52	I4.F312	I4.L305	blt1_off	16.1892	0	No	No	No	No	4	7
53	I4.L305	I4.V301	blt1_off	14.1857	0	No	No	No	No	7	3
54	7x62	I4.V301	blt1_off	12.1763	0	No	Yes	No	No	6	3
55	6x51	Lig	blt1_off	16.696	0	Yes	Yes	Yes	Yes	6	0
56	6x51	6x52	blt1_off	10.5595	8.63102	Yes	Yes	Yes	Yes	6	8
57	6x47	7x45	Shared	22.9965	47.9804	No	No	No	No	7	9
58	6x48	7x45	Shared	24.0656	49.5447	Yes	Yes	No	No	9	9
59	6x48	Lig	Shared	77.2847	69.3206	Yes	Yes	Yes	Yes	9	0
60	1x39	7x42	Shared	10.2988	29.0995	No	No	Yes	No	7	6
61	2x53	7x46	Shared	100	81.9052	Yes	No	No	No	6	9
62	2x50	7x46	Shared	98.8284	81.376	No	Yes	No	No	9	9
63	2x53	7x42	Shared	12.232	84.3334	Yes	No	Yes	No	6	6
64	2x50	7x49	Shared	93.266	43.4275	No	Yes	No	No	9	9
65	6x44	6x48	Shared	74.7042	19.6124	Yes	No	Yes	Yes	9	9
66	2x39	I2x57	Shared	25.9871	12.2655	No	No	Yes	No	7	7
67	2x60	Lig	Shared	27.7299	48.961	Yes	No	Yes	Yes	6	0
68	5x39	5x43	Shared	10.949	26.2744	Yes	Yes	Yes	No	5	5
69	3x47	5x57	Shared	14.4757	26.2355	No	No	No	No	9	6
70	3x50	5x58	Shared	14.2941	10.3743	Yes	No	Yes	Yes	9	8
71	3x51	5x57	Shared	12.0504	23.3481	No	No	No	No	8	6
72	6x51	7x34	Shared	16.5436	24.3832	Yes	Yes	Yes	No	6	4
73	6x58	7x34	Shared	20.4979	18.3049	Yes	Yes	Yes	No	3	4
74	5x47	6x52	Shared	17.1265	11.9231	Yes	Yes	Yes	Yes	8	8
75	5x47	6x49	Shared	13.0199	12.9349	Yes	Yes	No	No	8	6
76	5x61	5x65	Shared	16.8776	14.5926	No	No	Yes	No	8	8
77	5x65	I3.R215	Shared	10.5653	11.6351	Yes	No	Yes	No	8	5
78	1x38	7x36	blt1_on	0	10.5534	No	No	No	No	5	6
79	1x38	7x39	blt1_on	2.38723	15.8689	No	No	No	No	5	4
80	1x39	7x39	blt1_on	0	18.087	No	No	No	No	7	4
81	7x42	Lig	blt1_on	6.37083	100	Yes	No	Yes	Yes	6	0
82	2x64	Lig	blt1_on	2.20562	10.6857	No	Yes	Yes	Yes	3	0
83	1x46	7x47	blt1_on	1.19508	15.1763	No	No	Yes	No	8	7
84	1x46	1x50	blt1_on	0	19.4568	No	No	No	Yes	8	9
85	2x50	7x50	blt1_on	0	63.9972	No	Yes	No	No	9	9
86	1x53	7x50	blt1_on	0	69.5618	No	No	No	No	8	9
87	1x53	7x55	blt1_on	0	63.0166	No	No	No	Yes	8	7
88	1x52	7x55	blt1_on	0	11.8141	No	Yes	No	Yes	6	7
89	7x55	7x62	blt1_on	0	48.2061	No	Yes	No	Yes	7	6
90	1x56	1x60	blt1_on	0	13.0205	No	No	No	No	7	5
91	1x57	7x62	blt1_on	0	27.0916	No	Yes	No	Yes	7	6
92	1x57	2x40	blt1_on	0	12.7403	No	Yes	No	No	7	7
93	1x57	2x43	blt1_on	9.628	13.5497	No	Yes	No	Yes	7	7
94	7x61	7x62	blt1_on	0	13.6898	No	No	No	Yes	7	6
95	2x43	7x61	blt1_on	0	11.6507	No	Yes	No	No	7	7
96	2x39	2x43	blt1_on	0	16.4916	No	No	No	Yes	7	7
97	2x46	7x49	blt1_on	0	41.9177	No	Yes	No	No	9	9
98	3x37	Lig	blt1_on	0	62.355	Yes	Yes	Yes	Yes	7	0
99	3x37	4x53	blt1_on	0	41.9332	Yes	Yes	No	No	7	8
100	3x38	4x53	blt1_on	1.16286	32.4539	No	No	No	No	6	8
101	3x38	4x50	blt1_on	2.32279	30.8662	No	No	No	No	6	9
102	2x45	4x50	blt1_on	4.62507	27.7687	No	No	No	No	9	9
103	2x45	4x46	blt1_on	5.76743	26.3055	No	No	Yes	No	9	7
104	2x46	7x53	blt1_on	0	29.7144	No	Yes	Yes	Yes	9	9
105	2x60	3x29	blt1_on	1.57293	47.6691	Yes	No	No	Yes	6	6
106	3x25	3x29	blt1_on	0	49.2957	No	No	No	Yes	9	6
107	3x25	E1x50	blt1_on	1.52021	31.9013	No	No	Yes	Yes	9	8
108	E1x50	E1x52	blt1_on	9.07733	22.9201	Yes	Yes	Yes	Yes	8	7
109	4x61	Lig	blt1_on	0	49.1478	No	No	Yes	Yes	4	0
110	3x29	4x61	blt1_on	0	47.887	No	Yes	No	No	6	4
111	3x29	4x65	blt1_on	1.56708	46.4939	No	Yes	Yes	No	6	5
112	4x65	E2x51	blt1_on	0	38.8435	Yes	No	No	Yes	5	3
113	E2.L167	E2x51	blt1_on	0	27.9477	No	No	No	Yes	3	3
114	E2.L167	E2.W161	blt1_on	4.56649	23.854	No	No	No	No	3	2
115	E2.M165	E2.W161	blt1_on	1.52607	17.0753	No	Yes	No	No	3	2
116	3x25	E2x50	blt1_on	0.00292912	14.3747	No	No	No	No	9	9
117	E2.V158	E2x50	blt1_on	0	11.3161	No	No	No	No	4	9
118	3x34	4x53	blt1_on	0	10.888	No	Yes	No	No	5	8
119	3x37	3x41	blt1_on	0	15.1918	Yes	Yes	Yes	No	7	5
120	3x50	7x53	blt1_on	0	11.713	Yes	No	Yes	Yes	9	9
121	3x47	5x58	blt1_on	0	31.9636	No	No	Yes	Yes	9	8
122	6x40	7x53	blt1_on	0.0439367	22.2274	No	No	Yes	Yes	7	9
123	5x58	6x40	blt1_on	0	29.3252	Yes	Yes	No	No	8	7
124	6x43	6x47	blt1_on	0	45.5677	No	No	No	No	6	7
125	6x43	7x52	blt1_on	0.00585823	44.7428	No	No	No	Yes	6	8
126	6x40	7x52	blt1_on	0	33.9715	No	No	No	Yes	7	8
127	3x51	5x61	blt1_on	0	20.4452	No	No	No	No	8	8
128	2x41	4x46	blt1_on	4.62507	25.0992	No	No	Yes	No	6	7
129	2x41	4x39	blt1_on	0	23.6283	No	No	No	No	6	4
130	4x38	4x39	blt1_on	0	19.6358	No	No	No	No	6	4
131	4x38	4x41	blt1_on	3.47686	17.4877	No	No	No	No	6	3
132	4x41	I2x56	blt1_on	0	15.3242	No	No	No	No	3	4
133	I2x52	I2x56	blt1_on	6.11306	11.1993	No	No	No	No	5	4
134	5x43	Lig	blt1_on	0	41.7075	Yes	No	Yes	Yes	5	0
135	5x39	E2.Y172	blt1_on	2.64792	16.764	Yes	Yes	Yes	Yes	5	4
136	E2.V159	E2x51	blt1_on	0	13.8454	No	No	No	Yes	3	3
137	5x36	E2.Y172	blt1_on	6.157	12.2422	Yes	No	Yes	Yes	4	4
138	5x43	6x55	blt1_on	0.644405	25.8853	Yes	No	Yes	No	5	6
139	5x40	6x55	blt1_on	1.3679	23.4337	No	No	Yes	No	4	6
140	5x40	6x58	blt1_on	0	17.1998	No	No	Yes	Yes	4	3
141	7x38	Lig	blt1_on	7.99063	21.2779	No	No	Yes	Yes	5	0
142	6x51	7x38	blt1_on	0	19.6124	Yes	Yes	No	No	6	5
143	6x48	6x52	blt1_on	9.59578	23.3014	Yes	Yes	Yes	Yes	9	8
144	5x47	6x44	blt1_on	5.95782	10.063	Yes	Yes	Yes	No	8	9
145	6x36	7x52	blt1_on	0	23.3403	No	No	No	Yes	7	8
146	6x36	7x58	blt1_on	0	19.3167	No	No	No	Yes	7	4
147	6x58	7x30	blt1_on	0	29.2708	Yes	Yes	Yes	No	3	5
148	6x61	7x30	blt1_on	5.48037	22.8734	Yes	Yes	Yes	No	2	5
149	2x41	I1x51	blt1_on	1.157	14.4992	No	No	No	No	6	6
150	1x50	2x50	blt1_on	9.65143	22.78	No	Yes	No	Yes	9	9
151	2x40	I1x51	blt1_on	0	13.7676	No	No	No	No	7	6

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
1x32	2x64	Shared	6.01	1.5	0	0	2	1
1x39	7x42	Shared	10.96	4.87	0	0	2	1
2x53	3x32	blt1_off	3.42	0	1	0	1	1
2x53	3x35	Shared	6.46	4.85	1	0	1	2
2x53	7x42	Shared	3.93	2.62	1	0	1	1
2x53	7x46	Shared	3.23	6.46	1	0	1	2
2x53	Lig	blt1_off	3.51	0	1	0	1	0
2x56	2x60	blt1_off	5.19	0	0	0	2	1
2x56	3x32	Shared	3.38	6.76	0	0	2	1
2x60	3x28	blt1_off	4.19	0	1	0	1	2
2x60	3x29	Shared	9.05	6.79	1	0	1	1
2x60	7x42	blt1_off	4.29	0	1	0	1	1
2x60	Lig	Shared	15.79	18.93	1	0	1	0
2x64	Lig	Shared	5.71	11.18	0	0	1	0
3x29	4x65	Shared	29.34	14.67	1	0	1	1
3x29	Lig	blt1_off	22.73	0	1	0	1	0
3x30	4x61	blt1_off	3.79	0	5	8	2	1
3x32	Lig	blt1_off	7.48	0	1	0	1	0
3x36	5x43	blt1_off	6.77	0	1	1	1	1
3x36	6x48	Shared	11.63	3.49	1	1	1	1
3x36	6x52	blt1_off	3.94	0	1	1	1	2
3x37	4x56	Shared	9.38	10.55	0	1	1	2
3x37	5x46	Shared	6.24	3.75	0	1	1	2
3x37	5x461	blt1_off	4.35	0	0	1	1	2
4x61	4x65	blt1_off	3.92	0	0	0	1	1
4x65	E2x52	Shared	18.74	15.85	1	3	1	1
4x65	Lig	blt1_off	12.17	0	1	3	1	0
E2x51	E2x52	Shared	13	4.33	1	3	1	1
E2x51	Lig	blt1_off	5.02	0	1	3	1	0
E2.Y172	E2x52	Shared	8.34	8.34	1	3	2	1
E2x52	Lig	blt1_off	7.74	0	1	3	1	0
5x39	E2.Y172	Shared	6.53	11.98	1	3	2	2
5x39	5x43	Shared	4.92	7.39	1	3	2	1
5x43	6x51	blt1_off	6.73	0	1	0	1	1
5x43	6x52	blt1_off	3.69	0	1	0	1	2
5x43	6x55	Shared	6.57	2.63	1	0	1	2
6x44	6x48	Shared	21.05	5.01	1	1	2	1
6x48	6x51	blt1_off	6.75	0	1	1	1	1
6x48	6x52	Shared	5.29	3.17	1	1	1	2
6x48	7x41	Shared	5.19	5.19	1	1	1	1
6x48	7x45	Shared	7.41	7.41	1	1	1	2
6x48	Lig	Shared	8.05	3.54	1	1	1	0
6x51	6x52	Shared	8.71	5.44	1	0	1	2
6x51	6x55	Shared	11.63	15.12	1	0	1	2
6x51	7x34	Shared	3.09	6.17	1	0	1	2
6x51	Lig	blt1_off	4.84	0	1	0	1	0
6x55	7x34	blt1_off	12.05	0	1	0	2	2
7x34	7x38	blt1_off	3.76	0	1	10	2	1
7x35	Lig	Shared	5.66	6.83	0	0	1	0
7x38	Lig	Shared	15.14	6.21	0	0	1	0
7x41	Lig	blt1_off	3.71	0	1	0	1	0
7x42	Lig	Shared	9.33	3.03	1	0	1	0
3x30	4x57	Shared	2.67	2.67	5	8	2	2
3x37	4x57	blt1_off	2.67	0	0	1	1	2
E2.R171	E2x51	blt1_off	2.14	0	0	0	2	1
3x32	3x33	Shared	1.96	1.96	1	0	1	1
1x35	2x64	blt1_on	0	3.15	0	0	2	1
1x36	2x64	blt1_on	0	2.85	0	0	2	1
3x25	3x29	blt1_on	0	4.42	2	2	2	1
3x29	4x61	blt1_on	0	4.15	1	0	1	1
3x36	Lig	blt1_on	0	5.27	1	1	1	0
3x37	4x53	blt1_on	0	2.54	0	1	1	2
3x37	Lig	blt1_on	0	4.37	0	1	1	0
4x56	5x46	blt1_on	0	2.95	0	1	2	2
4x61	Lig	blt1_on	0	2.78	0	0	1	0
4x65	E2x51	blt1_on	0	4.28	1	3	1	1
E2.V159	E2x51	blt1_on	0	6.55	0	0	2	1
5x43	Lig	blt1_on	0	8.24	1	0	1	0
6x51	7x38	blt1_on	0	4.84	1	0	1	1
E2.L167	E2x51	blt1_on	0	2.44	0	0	2	1
3x33	Lig	blt1_on	0	2.13	0	0	1	0
3x37	3x41	blt1_on	0	1.93	0	1	1	2
5x461	6x52	blt1_on	0	1.59	0	0	2	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	blt1_off	7K15-BLT₁-MKD046-Na
	blt1_on	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2

Network Difference
Value	blt1_off	blt1_on
I_min	3.02	2.54
Number of Linked Nodes	276	256
Number of Specific Nodes	39 (14.13%)	19 (7.42%)
Number of Shared Nodes	237 (85.87%)	237 (92.58%)
Number of Links	320	275
Number of Specific Links	165 (51.56%)	120 (43.64%)
Number of Shared Links	155 (48.44%)	155 (56.36%)
Number of Hubs	42	33
Number of Specific Hubs	26 (61.90%)	17 (51.52%)
Number of Shared Hubs	16 (38.10%)	16 (48.48%)
Average % Shared Neighbours (Jaccard)	34.36
Average % Shared Neighbours (Otsuka)	43.60
Average % Shared Neighbours (Overlap Coefficient)	53.14
Average % Shared Cliques (k3-6)	77.72
Graphlets Similarity	0.51447

Paths Difference
Value	blt1_off	blt1_on
Number Of Nodes in MetaPath	77	90
Specific Nodes in MetaPath	31 (40.26%)	44 (48.89%)
Shared Nodes in MetaPath	237 (85.87%)	237 (85.87%)
Number Of Links MetaPath	77	95
Specific Links in MetaPath	56 (72.73%)	74 (77.89%)
Shared Links in MetaPath	155 (48.44%)	155 (48.44%)
Number of Shortest Paths	73264	39793
Length Of Smallest Path	3	3
Average Path Length	14.9399	12.0865
Length of Longest Path	39	31
Minimum Path Strength	1.43	1.38
Average Path Strength	6.11402	4.88058
Maximum Path Strength	24.04	15.26
Minimum Path Correlation	0.7	0.7
Average Path Correlation	0.931822	0.924765
Maximum Path Correlation	0.99	0.99
Minimum % Of Corr. Nodes	4.34783	4.34783
Average % Of Corr. Nodes	51.4575	51.8234
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	40.9631	36.0964
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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