Orange: nodes, hubs and links specific of blt1_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of blt1_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner blt1_on_gp Avg Int. Strength blt1_off Avg Int. Strength blt1_on_gp Num Of Links blt1_off Num Of Links ConSurf
11x50 blt1_on_gp6.8656.19833439
21x57 blt1_on_gp4.934.21333437
3I1x49 blt1_on_gp8.6150406
42x46 blt1_on_gp4.6184.15519
52x64 blt1_on_gp4.673.67167433
63x29 blt1_on_gp7.507514.6833436
73x34 blt1_on_gp4.6455.8025425
83x50 blt1_on_gp7.02756.6225429
9I2x51 blt1_on_gp4.92250.62415
10E2 blt1_on_gp13.865501103
115x46 blt1_on_gp4.41259.245425
125x51 blt1_on_gp4.28.2175526
135x58 blt1_on_gp5.27.765538
145x64 blt1_on_gp5.8957.145415
15I3 blt1_on_gp5.328750804
16E3 blt1_on_gp8.11250403
177x53 blt1_on_gp5.2445.515539
187x55 blt1_on_gp3.71751.22417
197x58 blt1_on_gp2.60750.953333434
207x62 blt1_on_gp5.233.645526
21G.HN.43 blt1_on_gp3.56250409
22G.S1.02 blt1_on_gp5.03250405
23G.H1.01 blt1_on_gp2.983330609
24G.H1.10 blt1_on_gp4.2550408
25G.S3.02 blt1_on_gp5.73750404
26G.S3.04 blt1_on_gp9.9350406
27G.S3.05 blt1_on_gp3.610507
28G.S3.06 blt1_on_gp8.15250405
29G.S3.08 blt1_on_gp5.51750409
30G.h2s4.01 blt1_on_gp4.3260509
31G.S4.04 blt1_on_gp5.73250409
32G.S4.05 blt1_on_gp3.520407
33G.s4h3.03 blt1_on_gp6.1850408
34G.s4h3.04 blt1_on_gp6.88750408
35G.s4h3.05 blt1_on_gp5.9860509
36G.H3.09 blt1_on_gp5.4320509
37G.H3.13 blt1_on_gp4.0260505
38G.H3.17 blt1_on_gp8.620405
39G.H3.18 blt1_on_gp5.330409
40G.S5.04 blt1_on_gp3.62250409
41G.S5.05 blt1_on_gp3.546670609
42G.HG.04 blt1_on_gp4.121670609
43G.HG.15 blt1_on_gp4.730407
44G.hgh4.01 blt1_on_gp4.210406
45G.hgh4.02 blt1_on_gp4.286670607
46G.H4.03 blt1_on_gp5.22750404
47G.H4.11 blt1_on_gp3.03750407
48G.H4.15 blt1_on_gp3.1650408
49G.h4s6.02 blt1_on_gp4.3450408
50G.S6.02 blt1_on_gp6.690507
51G.S6.04 blt1_on_gp6.990409
52G.H5.08 blt1_on_gp4.0950408
53G.H5.23 blt1_on_gp4.09750404
54b.lhb1x6 blt1_on_gp3.9180503
55b.b1x6 blt1_on_gp6.10409
56b.l1x3 blt1_on_gp8.0940509
57b.b2x5 blt1_on_gp7.2280507
58b.b3x6 blt1_on_gp6.54750409
59b.l3x2 blt1_on_gp4.790509
60b.b4x6 blt1_on_gp9.640409
61b.l4x2 blt1_on_gp9.92750404
62b.b5x3 blt1_on_gp6.8180509
63b.b5x5 blt1_on_gp3.90250405
64b.l5x1 blt1_on_gp4.17250408
65b.l5x5 blt1_on_gp6.312860709
66b.b6x5 blt1_on_gp3.53250406
67b.l6x5 blt1_on_gp5.5050404
68b.b7x1 blt1_on_gp5.85250404
69b.l7x2 blt1_on_gp4.68750409
70b.b8x4 blt1_on_gp4.7820506
71b.b9x4 blt1_on_gp5.54750409
72b.l9x3 blt1_on_gp5.305710709
73b.l9x6 blt1_on_gp4.5840508
74b.b10x5 blt1_on_gp4.0050609
75b.l10x1 blt1_on_gp3.9450403
76b.l11x2 blt1_on_gp6.9180509
77b.b12x6 blt1_on_gp8.026670608
78b.l12x1 blt1_on_gp3.40750406
79b.b13x3 blt1_on_gp6.08750404
80b.b13x7 blt1_on_gp5.6940507
81b.l13x3 blt1_on_gp6.474290709
82b.l13x6 blt1_on_gp4.2920509
83b.b14x3 blt1_on_gp3.59750405
84b.b15x1 blt1_on_gp5.0540509
85b.b15x3 blt1_on_gp3.9850409
86b.l15x2 blt1_on_gp5.0550409
87b.b16x4 blt1_on_gp9.2150406
88b.b16x5 blt1_on_gp3.47250405
89b.b16x6 blt1_on_gp7.0820508
90b.b17x7 blt1_on_gp6.760408
91b.l17x3 blt1_on_gp8.480509
92b.l17x6 blt1_on_gp5.4060509
93b.b18x3 blt1_on_gp4.0150408
94b.b18x5 blt1_on_gp4.28750405
95b.l18x1 blt1_on_gp5.551430706
96b.b19x2 blt1_on_gp5.410506
97b.b19x4 blt1_on_gp4.40408
98b.l19x2 blt1_on_gp7.1360509
99b.b20x3 blt1_on_gp2.6160508
100b.b20x4 blt1_on_gp8.6880508
101b.b20x6 blt1_on_gp5.671670606
102b.b20x7 blt1_on_gp2.81750409
103b.l20x2 blt1_on_gp5.74750409
104b.b21x7 blt1_on_gp4.2240505
105b.b22x5 blt1_on_gp3.4920507
106b.l22x5 blt1_on_gp6.470409
107b.b23x6 blt1_on_gp4.8880507
108b.b24x5 blt1_on_gp3.06750405
109b.b24x7 blt1_on_gp5.82250409
110b.b25x3 blt1_on_gp4.1650405
111b.b25x7 blt1_on_gp5.7750407
112b.l25x3 blt1_on_gp9.10750409
113b.l26x3 blt1_on_gp6.26250407
114b.b27x3 blt1_on_gp3.92750408
115b.l27x1 blt1_on_gp12.3460509
116b.l27x2 blt1_on_gp7.2060509
117b.b28x4 blt1_on_gp4.92750406
118b.b28x6 blt1_on_gp6.5480509
119g.h1x13 blt1_on_gp3.4850409
120g.l1x6 blt1_on_gp4.79250408
121g.h2x13 blt1_on_gp4.66750406
122g.ctx5 blt1_on_gp4.8650609
123g.ctx8 blt1_on_gp3.2880506
124g.ctx17 blt1_on_gp5.6350409
125g.ctx18 blt1_on_gp5.1350608
1262x50 Shared6.185.79875549
127E1x50 Shared7.5286.33611598
128E1x52 Shared5.48510.3287447
1293x37 Shared4.6286.25625547
130I2x57 Shared7.04257.23447
1315x39 Shared6.6953.816455
1325x47 Shared5.1726.81558
1335x50 Shared4.2956.4675449
1346x44 Shared4.29257.86125449
1356x48 Shared4.6359.34714679
1366x51 Shared7.89257.01466
1376x52 Shared4.1425.604558
1386x58 Shared2.8826.24875543
1397x42 Shared3.25756.79875446
140Lig Shared6.591829.3754211120
1412x60 blt1_off12.866.09833266
1423x30 blt1_off5.675.786355
1433x41 blt1_off4.115.09355
1443x44 blt1_off4.483334.31875347
1453x51 blt1_off4.814.38248
1464x49 blt1_off2.484.0575346
1474x64 blt1_off9.724.232354
1484x65 blt1_off11.611.6775345
149E2x52 blt1_off9.506676.14354
150E2.Y174 blt1_off05.02375040
1515x35 blt1_off6.15.17375242
1525x36 blt1_off7.783335.51167364
1535x40 blt1_off2.854.26344
1545x43 blt1_off6.086675.44345
1555x65 blt1_off2.683332.42875348
1566x47 blt1_off3.496674.095347
1576x55 blt1_off6.833339.04375346
1586x61 blt1_off8.293.1075342
1597x30 blt1_off3.5653.08875245
1607x34 blt1_off4.093336.04364
1617x49 blt1_off6.84.42375249
162E2.Y172 blt1_off05.26875040
163CT.G309 blt1_off01.21375040
   
Orange: nodes, hubs and links specific of blt1_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of blt1_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner blt1_on_gp Recurrence blt1_off Recurrence blt1_on_gp Hub1? blt1_off Hub1? blt1_on_gp Hub2? blt1_off Hub2? ConSurf1 ConSurf2
12x50 7x50 blt1_on_gp10.24980YesYesNoNo99
23x43 6x44 blt1_on_gp55.42094.93506NoNoYesYes89
33x43 7x53 blt1_on_gp55.72550NoNoYesNo89
43x50 7x53 blt1_on_gp38.36860YesNoYesNo99
55x65 I3 blt1_on_gp81.91520NoYesYesNo84
6G.S6.02 I3 blt1_on_gp88.73380YesNoYesNo74
7G.H5.10 G.S6.02 blt1_on_gp94.37840NoNoYesNo67
8G.H5.10 G.S5.03 blt1_on_gp94.54450NoNoNoNo68
9G.S5.03 G.S5.05 blt1_on_gp47.47220NoNoYesNo89
10G.S5.05 G.S6.04 blt1_on_gp51.14820YesNoYesNo99
11G.S6.04 G.s6h5.05 blt1_on_gp98.71340YesNoNoNo99
12G.s6h5.02 G.s6h5.05 blt1_on_gp98.90090NoNoNoNo79
13G.HG.01 G.s6h5.02 blt1_on_gp99.08790NoNoNoNo57
14G.H4.03 G.HG.01 blt1_on_gp99.27450YesNoNoNo45
15G.H4.03 G.HG.04 blt1_on_gp66.55370YesNoYesNo49
16G.HG.04 G.s4h3.01 blt1_on_gp33.47440YesNoNoNo97
17G.S5.06 G.s4h3.01 blt1_on_gp33.48170NoNoNoNo87
18G.S5.04 G.S5.06 blt1_on_gp66.25110YesNoNoNo98
19G.S4.04 G.S5.04 blt1_on_gp65.7610YesNoYesNo99
20G.H3.08 G.S4.04 blt1_on_gp1000NoNoYesNo99
21G.H2.04 G.H3.08 blt1_on_gp99.94590NoNoNoNo99
22G.H2.04 G.H2.07 blt1_on_gp99.83950NoNoNoNo99
23G.H2.07 G.S3.08 blt1_on_gp99.78540NoNoYesNo99
24G.S2.01 G.S3.08 blt1_on_gp47.46450NoNoYesNo99
25G.S2.01 b.l5x5 blt1_on_gp36.78970NoNoYesNo99
26b.l3x1 b.l5x5 blt1_on_gp72.29320NoNoYesNo99
27b.b2x1 b.l3x1 blt1_on_gp72.13260NoNoNoNo89
28b.b2x1 b.l27x1 blt1_on_gp71.63120NoNoYesNo89
29b.l25x6 b.l27x1 blt1_on_gp70.80680NoNoYesNo89
30b.l23x1 b.l25x6 blt1_on_gp70.6470NoNoNoNo68
31b.l21x7 b.l23x1 blt1_on_gp70.32770NoNoNoNo56
32b.b23x6 b.l21x7 blt1_on_gp70.00910YesNoNoNo75
33b.b23x6 b.b24x6 blt1_on_gp65.00410YesNoNoNo78
34b.b21x7 b.b24x6 blt1_on_gp64.84480YesNoNoNo58
35b.b21x5 b.b21x7 blt1_on_gp62.79590NoNoYesNo45
36b.b21x5 b.h2x1 blt1_on_gp62.63210NoNoNoNo45
37b.h2x1 b.h2x5 blt1_on_gp61.48370NoNoNoNo55
38b.h2x5 b.lhb1x3 blt1_on_gp61.31950NoNoNoNo52
39b.l22x5 b.lhb1x3 blt1_on_gp60.6620YesNoNoNo92
406x40 7x53 blt1_on_gp38.340NoNoYesNo79
415x58 6x40 blt1_on_gp39.59360YesNoNoNo87
42G.H5.06 G.S5.03 blt1_on_gp47.24030NoNoNoNo38
43G.H5.06 G.S6.04 blt1_on_gp47.31650NoNoYesNo39
44G.H4.03 G.H4.07 blt1_on_gp33.03730YesNoNoNo45
45G.H4.07 G.S6.05 blt1_on_gp33.03880NoNoNoNo54
46G.S5.06 G.S6.05 blt1_on_gp32.80120NoNoNoNo84
47G.H4.11 G.HG.04 blt1_on_gp33.59870YesNoYesNo79
48G.H4.11 G.H4.15 blt1_on_gp33.56490YesNoYesNo78
49G.H4.15 G.S4.06 blt1_on_gp33.83550YesNoNoNo87
50G.S4.04 G.S4.06 blt1_on_gp33.84320YesNoNoNo97
51G.S3.08 G.h2s4.01 blt1_on_gp38.20390YesNoYesNo99
52G.h2s4.01 b.l5x5 blt1_on_gp36.84710YesNoYesNo99
532x46 7x49 blt1_on_gp18.1370YesNoNoYes99
54b.l22x5 g.ctx8 blt1_on_gp51.87860YesNoYesNo96
55g.ctx5 g.ctx8 blt1_on_gp51.47640YesNoYesNo96
56g.ctx5 g.ctx6 blt1_on_gp51.10680YesNoNoNo97
57b.l26x5 g.ctx6 blt1_on_gp48.48550NoNoNoNo57
58b.l26x5 g.ctx17 blt1_on_gp46.94280NoNoYesNo59
59g.ctx17 g.ctx18 blt1_on_gp42.75220YesNoYesNo98
60b.b1x4 g.ctx18 blt1_on_gp41.81380NoNoYesNo78
61b.b1x4 b.b5x1 blt1_on_gp20.82160NoNoNoNo75
62b.b1x6 b.b5x1 blt1_on_gp20.64810YesNoNoNo95
63b.b1x6 b.b4x6 blt1_on_gp40.59590YesNoYesNo99
64b.b4x6 b.b5x3 blt1_on_gp31.79140YesNoYesNo99
65G.HN.43 b.b5x3 blt1_on_gp30.76170YesNoYesNo99
66G.HN.39 G.HN.43 blt1_on_gp29.02160NoNoYesNo59
67b.b1x4 b.b28x5 blt1_on_gp20.82160NoNoNoNo75
68b.b1x6 b.b28x5 blt1_on_gp20.64810YesNoNoNo95
69G.HN.39 b.b5x5 blt1_on_gp28.66960NoNoYesNo55
70G.S3.08 G.s3h2.03 blt1_on_gp14.09870YesNoNoNo99
71G.S2.01 b.l7x2 blt1_on_gp10.60650NoNoYesNo99
72G.s3h2.03 b.l7x2 blt1_on_gp11.0560NoNoYesNo99
73b.l7x2 b.l9x6 blt1_on_gp22.08740YesNoYesNo98
74G.H2.06 b.l9x6 blt1_on_gp12.32710NoNoYesNo98
75G.H2.06 b.l17x6 blt1_on_gp11.97540NoNoYesNo99
76b.l17x5 b.l17x6 blt1_on_gp11.54880NoNoYesNo69
77b.l17x5 b.l19x2 blt1_on_gp11.40330NoNoYesNo69
78b.b4x5 b.b5x5 blt1_on_gp13.80580NoNoYesNo75
79b.b3x3 b.b4x5 blt1_on_gp13.09960NoNoNoNo87
80b.b3x3 b.b4x3 blt1_on_gp12.74640NoNoNoNo87
81b.b4x3 b.l5x1 blt1_on_gp24.78620NoNoYesNo78
82b.b5x5 b.l8x8 blt1_on_gp14.15980YesNoNoNo54
83b.b5x7 b.l8x8 blt1_on_gp13.45370NoNoNoNo74
84b.b4x3 b.b5x7 blt1_on_gp12.74730NoNoNoNo77
85b.b8x4 b.l5x1 blt1_on_gp20.54060YesNoYesNo68
86b.b7x2 b.b8x4 blt1_on_gp17.00480NoNoYesNo86
87b.b6x5 b.b7x2 blt1_on_gp16.29680YesNoNoNo68
88b.b6x5 b.l6x4 blt1_on_gp13.46440YesNoNoNo65
89b.l6x3 b.l6x4 blt1_on_gp12.75620NoNoNoNo65
902x46 7x53 blt1_on_gp19.90740YesNoYesNo99
916x48 Lig Shared39.181286.8496YesYesYesYes90
926x44 6x48 Shared45.656298.517YesYesYesYes99
933x50 5x58 Shared39.774412.6896YesNoYesNo98
943x47 5x58 Shared79.695725.199NoNoYesNo98
953x47 5x57 Shared80.046639.0658NoNoNoNo96
963x51 5x57 Shared80.216736.3008NoYesNoNo86
973x51 5x61 Shared80.386822.3502NoYesNoNo88
985x61 5x65 Shared80.726816.6946NoNoNoYes88
992x50 7x49 Shared17.775589.6984YesYesNoYes99
1007x32 7x35 blt1_off012.4592NoNoNoNo24
1017x35 Lig blt1_off0.36675813.5149NoNoYesYes40
1026x48 7x45 blt1_off0.027246817.7377YesYesNoNo99
1036x47 7x45 blt1_off0.20213216.1667NoYesNoNo79
1046x47 7x43 blt1_off011.4034NoYesNoNo75
1057x42 Lig blt1_off4.8681311.7176YesYesYesYes60
1061x39 7x42 blt1_off4.4050311.8224NoNoYesYes76
1072x50 Lig blt1_off0100YesYesYesYes90
1081x50 2x50 blt1_off5.4773416.1709YesNoYesYes99
1091x50 2x51 blt1_off1.4679610.3393YesNoNoNo97
1107x49 7x53 blt1_off041.3238NoYesYesNo99
1112x43 7x53 blt1_off037.6163NoNoYesNo79
1121x57 2x43 blt1_off0.73408936.3636YesNoNoNo77
1131x57 2x40 blt1_off0.73406531.6003YesNoNoNo77
1142x40 I1x48 blt1_off0.36704430.222NoNoNoNo76
115CT.G309 I1x48 blt1_off027.7838NoYesNoNo06
1166x40 7x49 blt1_off055.2828NoNoNoYes79
1173x46 6x40 blt1_off032.3335NoNoNoNo87
1182x42 3x46 blt1_off0.37090929.669NoNoNoNo78
1192x42 4x46 blt1_off028.3243NoNoNoNo77
1206x36 6x40 blt1_off025.421NoNoNoNo77
1216x36 CT.F317 blt1_off024.0427NoNoNoNo70
1222x39 CT.F317 blt1_off023.054NoNoNoNo70
1232x39 I2x57 blt1_off0.18631418.5924NoNoYesYes77
1242x45 4x46 blt1_off0.36675819.0029NoNoNoNo97
1252x45 4x50 blt1_off0.73349217.5911NoNoNoNo99
1263x40 6x44 blt1_off093.4269NoNoYesYes89
1273x40 3x41 blt1_off052.279NoNoNoYes85
1283x41 4x49 blt1_off013.4562NoYesNoYes56
1292x60 Lig blt1_off5.8447941.7637NoYesYesYes60
1302x60 E1x50 blt1_off036.7742NoYesYesYes68
1312x63 E1x50 blt1_off0.7315619.3339NoNoYesYes58
1322x63 E2.L169 blt1_off012.4298NoNoNoNo50
133E2.L169 E2.T167 blt1_off011.3406NoNoNoNo00
134E2x52 Lig blt1_off048.8856NoYesYesYes40
135E2.Y174 E2x52 blt1_off023.628NoYesNoYes04
1364x60 5x39 blt1_off0.73330129.3548NoNoYesYes85
1374x59 4x60 blt1_off0.36666326.7826NoNoNoNo48
1383x30 4x59 blt1_off024.2019NoYesNoNo54
1393x30 4x62 blt1_off0.36675813.7956NoYesNoNo54
1403x26 4x62 blt1_off011.173NoNoNoNo74
141E2.Y172 E2x52 blt1_off023.628NoYesNoYes04
1426x48 6x52 blt1_off5.4675115.5383YesYesYesYes98
1433x38 4x50 blt1_off1.4668214.7424NoNoNoNo69
1443x38 4x53 blt1_off1.8334113.3054NoNoNoNo68
1453x37 4x53 blt1_off4.0319511.8601YesYesNoNo78
1463x40 5x50 blt1_off0.36675840.1005NoNoYesYes89
1473x41 3x44 blt1_off1.0999638.7767NoYesNoYes57
1483x44 5x50 blt1_off0.00019087137.6456NoYesYesYes79
1493x44 5x54 blt1_off068.4835NoYesNoNo78
1503x47 5x54 blt1_off0.18070765.819NoNoNoNo98
151I2x53 I2x57 blt1_off013.3054NoNoYesYes57
1523x52 I2x53 blt1_off0.45887710.4064NoNoNoNo55
1534x64 5x35 blt1_off0.36585112.0695NoYesNoYes42
1545x36 E2.Y174 blt1_off010.2597NoYesNoYes40
1555x36 E2.Y172 blt1_off010.2597NoYesNoYes40
1567x38 Lig blt1_off0.37465515.2995NoNoYesYes50
1577x34 7x38 blt1_off012.1533NoYesNoNo45
1586x58 7x34 blt1_off2.909320.2472YesYesNoYes34
1596x48 6x51 blt1_off026.5605YesYesYesYes96
1605x43 6x51 blt1_off010.486NoYesYesYes56
1615x47 6x52 blt1_off5.4577816.5857YesYesYesYes88
1626x58 7x30 blt1_off1.458919.2962YesYesNoYes35
1636x61 7x30 blt1_off010.4608NoYesNoYes25
1645x33 5x36 blt1_off1.4667222.212NoNoNoYes34
165CT.E311 CT.G309 blt1_off018.8479NoNoNoYes00
166CT.E311 CT.L304 blt1_off016.6695NoNoNoNo00
167CT.L304 CT.V315 blt1_off013.4018NoNoNoNo00
1687x61 CT.V315 blt1_off012.3125NoNoNoNo70
1697x61 CT.L316 blt1_off011.2233NoNoNoNo70
1705x33 6x62 blt1_off0.36673415.4629NoNoNoNo33
1716x59 6x62 blt1_off011.6087NoNoNoNo43
1725x39 5x43 blt1_off8.0509517.323YesYesNoYes55
1736x51 7x34 blt1_off4.3712715.2074YesYesNoYes64

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
1x397x42Shared9.7454.870021
1x502x50Shared5.38512.1201821
1x507x50Shared9.7758.1501822
2x507x46Shared7.365.8901812
2x507x49Shared5.3856.7301812
2x50Ligblt1_off5.065001810
2x533x35Shared6.464.851012
2x537x42Shared3.2752.621011
2x53Ligblt1_off8.601010
2x60E1x50blt1_off3.5101012
2x603x28blt1_off4.1901012
2x603x29Shared6.796.791011
2x607x42blt1_off3.21501011
2x60LigShared16.2918.931010
2x64LigShared6.4311.180010
3x25E1x50Shared11.19.141222
3x28E1x50blt1_off3.9201022
3x294x65Shared22.5714.671011
3x29Ligblt1_off14.6901010
3x32Ligblt1_off8.300010
3x366x48Shared11.633.491111
3x366x52blt1_off3.28501112
3x374x53Shared3.182.540112
3x374x56Shared9.3810.550112
3x375x46Shared8.1153.750112
3x375x461blt1_off4.3500112
3x396x44blt1_off3.300022
4x614x65blt1_off5.2300011
4x65E2x52Shared12.82515.851211
E2.Y174E2x52blt1_off3.33501021
5x39E2.Y174blt1_off4.35501222
5x395x43Shared3.0757.391221
5x436x51blt1_off6.1701012
5x436x55Shared9.132.631012
6x446x48Shared21.055.010121
6x486x51blt1_off4.8201112
6x486x52Shared4.763.171112
6x487x41Shared4.545.191112
6x487x45Shared7.417.411112
6x48LigShared11.223.541110
6x516x52Shared8.1655.441022
6x516x55Shared13.8615.121022
6x517x34Shared3.6056.171022
6x517x38Shared5.444.841021
6x557x34blt1_off8.40501022
7x347x38blt1_off5.01012321
7x35LigShared8.0956.830010
7x38LigShared12.96.211110
7x42LigShared10.963.031110
4x65Ligblt1_off6.08501210
E2x52Ligblt1_off3.8701210
3x365x43blt1_off3.38501111
E2x51E2x52Shared6.54.330221
E2.Y172E2x52blt1_off4.1701021
5x39E2.Y172blt1_off3.26501222
1x322x64Shared3.0051.50021
2x562x60blt1_off2.59500021
7x327x35blt1_off2.100021
3x323x33Shared1.961.960011
1x352x64Shared1.583.150021
1x362x64blt1_on_gp02.850021
2x503x39blt1_on_gp02.9401812
2x507x50blt1_on_gp03.2201812
2x537x46blt1_on_gp06.461012
2x563x32blt1_on_gp06.760021
3x253x29blt1_on_gp04.421221
3x294x61blt1_on_gp04.151011
3x36Ligblt1_on_gp05.271110
3x37Ligblt1_on_gp04.370110
4x565x46blt1_on_gp02.950122
4x61Ligblt1_on_gp02.780010
4x65E2x51blt1_on_gp04.281212
E2E2blt1_on_gp035.950222
E2E2x51blt1_on_gp08.990222
E2E2x52blt1_on_gp08.340221
5x39E2blt1_on_gp011.981222
5x43Ligblt1_on_gp08.241010
7x387x42blt1_on_gp02.511111
3x33Ligblt1_on_gp02.130010
3x373x41blt1_on_gp01.930112
5x4616x52blt1_on_gp01.590022

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
blt1_on_gp 7VKT-BLT1-LTB4-Gi1/β1/γ2
blt1_off 5X33-BLT1-BIIL260
7K15-BLT1-MKD046-Na
Network Difference
Value blt1_on_gp blt1_off
Imin 2.51 3.035
Number of Linked Nodes 814 308
Number of Specific Nodes 591 (72.60%) 85  (27.60%)
Number of Shared Nodes 223 (27.40%) 223  (72.40%)
Number of Links 952 335
Number of Specific Links 810 (85.08%) 193  (57.61%)
Number of Shared Links 142 (14.92%) 142  (42.39%)
Number of Hubs 140 38
Number of Specific Hubs 125 (89.29%) 23  (60.53%)
Number of Shared Hubs 15 (10.71%) 15  (39.47%)
Average % Shared Neighbours (Jaccard) 10.51
Average % Shared Neighbours (Otsuka) 13.15
Average % Shared Neighbours (Overlap Coefficient) 15.83
Average % Shared Cliques (k3-6) 75.69
Graphlets Similarity 0.606643
Paths Difference
Value blt1_on_gp blt1_off
Number Of Nodes in MetaPath 92 82
Specific Nodes in MetaPath 78 (84.78%) 68  (82.93%)
Shared Nodes in MetaPath 223 (27.40%) 223  (27.40%)
Number Of Links MetaPath 99 83
Specific Links in MetaPath 90 (90.91%) 74  (89.16%)
Shared Links in MetaPath 142 (14.92%) 142  (14.92%)
Number of Shortest Paths 4596207 60451
Length Of Smallest Path 3 3
Average Path Length 50.8145 12.9109
Length of Longest Path 83 31
Minimum Path Strength 1.16 0.7625
Average Path Strength 5.35778 5.65262
Maximum Path Strength 21.84 17.6975
Minimum Path Correlation 0.7 0.7
Average Path Correlation 0.99323 0.916604
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 1.72414 3.44828
Average % Of Corr. Nodes 28.5546 44.6825
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 42.9649 46.1132
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download blt1_off_on_gp.zip<



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