psnGPCR

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Orange: nodes, hubs and links specific of cb1_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of cb1_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	cb1_off Int. Strength	cb1_on Int. Strength	cb1_off Hub1?	cb1_on Hub1?	cb1_off Hub2?	cb1_on Hub2?	ConSurf1	ConSurf2
1	E2.P269	NT.E100	cb1_off	100	0	No	No	No	No	3	4
2	E2.H270	NT.E100	cb1_off	100	0	Yes	Yes	No	No	3	4
3	2x64	NT.N101	cb1_off	100	0	No	Yes	Yes	No	4	6
4	E1.K183	NT.N101	cb1_off	100	0	No	No	Yes	No	6	6
5	E1.D184	NT.N101	cb1_off	100	0	No	No	Yes	No	2	6
6	NT.F102	NT.M103	cb1_off	100	0	Yes	No	Yes	No	5	4
7	2x60	NT.F102	cb1_off	100	0	No	No	Yes	No	4	5
8	3x25	NT.F102	cb1_off	100	0	Yes	Yes	Yes	No	9	5
9	3x28	NT.F102	cb1_off	100	0	Yes	No	Yes	No	6	5
10	Lig	NT.F102	cb1_off	100	0	Yes	Yes	Yes	No	0	5
11	2x57	NT.M103	cb1_off	100	0	Yes	No	Yes	No	7	4
12	2x60	NT.M103	cb1_off	100	0	No	No	Yes	No	4	4
13	2x61	NT.M103	cb1_off	100	0	Yes	Yes	Yes	No	5	4
14	Lig	NT.M103	cb1_off	100	0	Yes	Yes	Yes	No	0	4
15	2x64	NT.D104	cb1_off	100	0	No	Yes	No	No	4	6
16	NT.E106	NT.I105	cb1_off	100	0	No	No	No	No	4	3
17	Lig	NT.I105	cb1_off	100	0	Yes	Yes	No	No	0	3
18	1x28	NT.M109	cb1_off	100	0	Yes	No	Yes	No	6	3
19	1x32	NT.M109	cb1_off	100	0	No	No	Yes	No	4	3
20	1x28	1x32	cb1_off	100	0	Yes	No	No	No	6	4
21	1x31	1x35	cb1_off	100	0	No	No	No	No	2	5
22	1x39	2x57	cb1_off	100	0	Yes	No	Yes	No	7	7
23	1x39	2x61	cb1_off	100	0	Yes	No	Yes	Yes	7	5
24	1x39	Lig	cb1_off	100	0	Yes	No	Yes	Yes	7	0
25	1x40	2x61	cb1_off	100	0	No	No	Yes	Yes	3	5
26	1x45	1x49	cb1_off	100	0	No	No	Yes	No	4	8
27	1x46	1x49	cb1_off	100	0	Yes	Yes	Yes	No	7	8
28	1x46	7x42	cb1_off	100	0	Yes	Yes	No	No	7	7
29	1x47	2x55	cb1_off	100	0	No	No	No	No	6	4
30	1x53	7x50	cb1_off	100	0	No	No	No	No	9	9
31	1x53	7x53	cb1_off	100	0	No	No	Yes	Yes	9	9
32	2x37	2x39	cb1_off	100	0	Yes	No	No	No	5	8
33	2x41	4x43	cb1_off	100	0	No	No	No	No	3	1
34	2x41	4x46	cb1_off	100	0	No	No	No	No	3	8
35	2x42	2x43	cb1_off	100	0	Yes	Yes	No	No	8	8
36	2x42	2x46	cb1_off	100	0	Yes	Yes	Yes	Yes	8	9
37	2x42	6x37	cb1_off	100	0	Yes	Yes	No	No	8	8
38	2x43	7x53	cb1_off	100	0	No	No	Yes	Yes	8	9
39	2x46	7x53	cb1_off	100	0	Yes	Yes	Yes	Yes	9	9
40	2x48	4x50	cb1_off	100	0	No	No	Yes	Yes	6	9
41	2x57	7x42	cb1_off	100	0	Yes	No	No	No	7	7
42	2x59	3x28	cb1_off	100	0	No	No	Yes	No	7	6
43	2x62	2x66	cb1_off	100	0	No	No	No	No	5	4
44	2x63	3x28	cb1_off	100	0	No	No	Yes	No	3	6
45	3x28	E1.D184	cb1_off	100	0	Yes	No	No	No	6	2
46	3x25	3x26	cb1_off	100	0	Yes	Yes	No	No	9	5
47	3x29	E2.F268	cb1_off	100	0	No	No	Yes	Yes	4	5
48	3x36	3x40	cb1_off	100	0	Yes	No	No	No	7	7
49	3x36	5x43	cb1_off	100	0	Yes	No	Yes	Yes	7	6
50	3x36	5x47	cb1_off	100	0	Yes	No	No	No	7	8
51	3x36	6x44	cb1_off	100	0	Yes	No	No	No	7	9
52	3x36	6x48	cb1_off	100	0	Yes	No	Yes	Yes	7	8
53	3x36	6x52	cb1_off	100	0	Yes	No	No	No	7	7
54	3x40	5x51	cb1_off	100	0	No	No	No	No	7	6
55	3x43	5x58	cb1_off	100	0	No	No	Yes	Yes	8	9
56	3x45	4x46	cb1_off	100	0	No	No	No	No	6	8
57	3x46	6x37	cb1_off	100	0	No	No	No	No	9	8
58	3x47	5x58	cb1_off	100	0	No	No	Yes	Yes	8	9
59	3x49	3x50	cb1_off	100	0	Yes	No	Yes	No	9	9
60	3x49	I2x57	cb1_off	100	0	Yes	No	Yes	No	9	6
61	3x50	3x53	cb1_off	100	0	Yes	No	No	No	9	8
62	3x50	I2x53	cb1_off	100	0	Yes	No	Yes	Yes	9	7
63	3x50	5x61	cb1_off	100	0	Yes	No	No	No	9	9
64	3x50	6x30	cb1_off	100	0	Yes	No	No	Yes	9	7
65	3x50	6x33	cb1_off	100	0	Yes	No	No	No	9	8
66	3x52	I2x57	cb1_off	100	0	No	No	Yes	No	5	6
67	3x53	6x30	cb1_off	100	0	No	No	No	Yes	8	7
68	3x56	I2x56	cb1_off	100	0	Yes	No	No	No	5	4
69	I2x52	I2x55	cb1_off	100	0	No	No	No	No	5	4
70	4x49	4x50	cb1_off	100	0	No	No	Yes	Yes	6	9
71	4x58	4x62	cb1_off	100	0	No	No	No	No	5	5
72	E2.C257	E2.E258	cb1_off	100	0	No	No	Yes	No	9	1
73	E2.I271	E2.S265	cb1_off	100	0	No	No	No	No	3	4
74	6x58	E2.S265	cb1_off	100	0	Yes	No	No	No	4	4
75	6x55	E2.I267	cb1_off	100	0	No	No	Yes	No	6	4
76	6x55	E2.F268	cb1_off	100	0	No	No	Yes	Yes	6	5
77	5x40	E2.I271	cb1_off	100	0	No	No	No	No	5	3
78	5x43	5x44	cb1_off	100	0	Yes	Yes	No	Yes	6	5
79	5x54	5x58	cb1_off	100	0	No	No	Yes	Yes	8	9
80	5x63	5x64	cb1_off	100	0	No	No	Yes	No	3	5
81	5x67	5x68	cb1_off	100	0	No	No	No	No	5	7
82	6x25	6x28	cb1_off	100	0	No	No	No	No	3	4
83	6x26	6x29	cb1_off	100	0	No	No	No	No	5	6
84	6x26	6x30	cb1_off	100	0	No	No	No	Yes	5	7
85	6x40	7x49	cb1_off	100	0	No	No	Yes	No	8	9
86	6x41	6x45	cb1_off	100	0	No	No	No	No	8	6
87	6x44	7x45	cb1_off	100	0	No	No	Yes	No	9	9
88	6x50	7x37	cb1_off	100	0	No	No	No	No	9	5
89	6x51	6x55	cb1_off	100	0	Yes	No	No	No	7	6
90	6x51	7x41	cb1_off	100	0	Yes	No	No	No	7	7
91	6x51	Lig	cb1_off	100	0	Yes	No	Yes	Yes	7	0
92	6x54	7x30	cb1_off	100	0	No	No	Yes	No	4	3
93	7x31	E3.M371	cb1_off	100	0	No	No	No	Yes	2	1
94	7x27	7x30	cb1_off	100	0	No	No	Yes	No	1	3
95	7x39	Lig	cb1_off	100	0	No	No	Yes	Yes	5	0
96	7x41	Lig	cb1_off	100	0	No	No	Yes	Yes	7	0
97	7x49	7x53	cb1_off	100	0	Yes	No	Yes	Yes	9	9
98	8x47	8x50	cb1_off	100	0	No	No	No	No	8	8
99	8x51	8x55	cb1_off	100	0	No	No	No	No	8	5
100	NT.E106	NT.L111	cb1_off	100	0	No	No	No	Yes	4	4
101	7x31	NT.F108	cb1_off	100	0	No	No	Yes	No	2	5
102	7x34	NT.F108	cb1_off	100	0	Yes	Yes	Yes	No	4	5
103	7x32	NT.M109	cb1_off	100	0	No	No	Yes	No	1	3
104	1x60	I1x48	cb1_off	100	0	No	No	No	No	6	6
105	4x63	E2.K259	cb1_off	100	0	No	No	No	No	5	4
106	5x42	E2.W255	cb1_off	100	0	No	No	Yes	Yes	6	5
107	5x37	6x59	cb1_off	100	0	No	No	Yes	Yes	3	4
108	5x59	5x63	cb1_off	100	0	No	No	No	No	3	3
109	6x32	7x56	cb1_off	100	0	No	No	No	No	7	7
110	6x44	6x48	cb1_off	100	0	No	No	Yes	Yes	9	8
111	1x53	2x47	cb1_off	50	0	No	No	No	No	9	9
112	5x66	6x31	cb1_off	50	0	No	No	Yes	No	5	5
113	1x43	2x57	cb1_off	0	0	No	No	Yes	No	6	7
114	2x46	3x39	cb1_off	0	0	Yes	Yes	No	No	9	9
115	1x56	8x50	cb1_off	50	0	Yes	No	No	No	8	8
116	2x51	2x55	cb1_off	0	0	No	No	No	No	7	4
117	5x40	6x59	cb1_off	50	0	No	No	Yes	Yes	5	4
118	6x43	7x45	cb1_off	50	0	No	No	Yes	No	6	9
119	1x42	7x47	cb1_off	50	0	No	No	Yes	Yes	6	7
120	6x31	6x35	cb1_off	50	0	Yes	No	No	No	5	7
121	2x41	4x39	cb1_off	50	0	No	No	No	Yes	3	1
122	2x38	4x42	cb1_off	50	0	No	No	No	No	5	7
123	1x36	2x61	cb1_off	0	0	No	No	Yes	Yes	5	5
124	7x40	7x43	cb1_off	0	0	No	No	No	No	7	5
125	5x36	E2.L260	cb1_off	50	0	Yes	Yes	No	No	5	3
126	1x57	2x44	cb1_off	0	0	No	No	No	No	7	6
127	2x43	2x44	cb1_off	50	0	No	No	No	No	8	6
128	5x62	5x66	cb1_off	50	0	No	No	No	No	6	5
129	NT.G99	NT.N101	cb1_off	50	0	No	No	Yes	No	6	6
130	5x58	6x38	cb1_off	50	0	Yes	Yes	No	No	9	6
131	5x65	6x31	cb1_off	0	0	No	No	Yes	No	8	5
132	5x39	5x43	cb1_off	50	0	No	Yes	Yes	Yes	7	6
133	7x47	7x48	cb1_off	50	0	Yes	Yes	No	No	7	6
134	7x30	7x33	cb1_off	0	0	Yes	No	No	No	3	4
135	4x44	4x48	cb1_off	0	0	No	No	No	No	3	3
136	4x55	4x59	cb1_off	0	0	No	No	No	No	3	5
137	5x62	6x38	cb1_off	0	0	No	No	No	No	6	6
138	NT.L111	NT.V110	cb1_off	50	0	No	Yes	No	No	4	3
139	1x44	1x48	cb1_off	0	0	No	No	No	No	5	3
140	7x29	7x32	cb1_off	50	0	No	No	No	No	4	1
141	E1.F180	E1.R182	cb1_off	50	0	No	No	No	No	4	4
142	5x53	5x57	cb1_off	50	0	No	No	No	No	6	7
143	7x35	NT.F108	cb1_off	50	0	No	No	Yes	No	4	5
144	2x53	Lig	cb1_off	0	0	No	No	Yes	Yes	8	0
145	5x49	5x53	cb1_off	50	0	No	No	No	No	6	6
146	2x57	2x58	cb1_off	0	0	Yes	No	No	No	7	7
147	3x30	4x57	cb1_off	0	0	No	No	No	No	6	7
148	7x36	NT.M109	cb1_off	50	0	No	No	Yes	No	4	3
149	7x28	NT.F108	cb1_off	50	0	No	No	Yes	No	3	5
150	4x50	4x54	cb1_off	0	0	Yes	Yes	No	No	9	4
151	4x43	4x47	cb1_off	0	0	No	No	No	No	1	4
152	6x49	6x52	cb1_off	50	0	No	No	No	No	5	7
153	4x54	4x58	cb1_off	0	0	No	No	No	No	4	5
154	6x60	6x61	cb1_off	0	0	No	No	No	No	5	3
155	1x38	1x39	cb1_off	0	0	No	No	Yes	No	5	7
156	4x52	4x56	cb1_off	0	0	No	Yes	No	No	5	5
157	I1.C149	I1x51	cb1_off	0	0	No	No	No	Yes	7	8
158	8x54	8x58	cb1_off	0	0	No	No	No	No	7	5
159	6x24	6x27	cb1_off	0	0	No	No	No	No	2	4
160	5x69	6x27	cb1_off	0	0	No	No	No	No	5	4
161	1x55	8x57	cb1_off	0	0	No	No	No	No	4	5
162	6x27	6x31	cb1_off	0	0	No	No	Yes	No	4	5
163	1x44	2x58	cb1_off	0	0	No	No	No	No	5	7
164	1x33	1x37	cb1_off	0	0	No	No	No	No	5	4
165	1x52	1x56	cb1_off	0	0	No	No	Yes	No	7	8
166	I2x51	I2x54	cb1_off	0	0	No	No	No	No	7	4
167	1x59	8x56	cb1_off	0	0	No	No	No	No	5	3
168	E2.E258	E2.Q261	cb1_off	0	0	Yes	No	No	No	1	1
169	1x31	NT.L111	Shared	100	100	No	No	No	Yes	2	4
170	1x28	1x29	Shared	100	100	Yes	No	No	No	6	2
171	1x46	2x54	Shared	100	100	Yes	Yes	No	Yes	7	7
172	1x46	7x47	Shared	100	100	Yes	Yes	Yes	Yes	7	7
173	1x47	2x54	Shared	100	33.3333	No	No	No	Yes	6	7
174	1x49	7x47	Shared	100	100	Yes	No	Yes	Yes	8	7
175	1x49	7x50	Shared	100	100	Yes	No	No	No	8	9
176	1x50	2x50	Shared	100	100	No	No	No	Yes	9	9
177	1x50	7x50	Shared	100	100	No	No	No	No	9	9
178	1x51	2x51	Shared	100	0	No	No	No	No	3	7
179	1x54	2x48	Shared	100	100	No	No	No	No	7	6
180	1x59	8x57	Shared	100	100	No	No	No	No	5	5
181	1x60	I1x50	Shared	100	100	No	No	No	Yes	6	9
182	1x60	8x53	Shared	100	66.6667	No	No	No	No	6	7
183	I1x48	I1x51	Shared	100	33.3333	No	No	No	Yes	6	8
184	2x40	I1x50	Shared	100	100	Yes	Yes	No	Yes	9	9
185	2x37	2x40	Shared	100	100	Yes	No	Yes	Yes	5	9
186	2x37	8x49	Shared	100	100	Yes	No	No	Yes	5	6
187	2x38	I2x57	Shared	100	100	No	No	Yes	No	5	6
188	2x39	2x40	Shared	100	100	No	No	Yes	Yes	8	9
189	2x40	8x47	Shared	100	100	Yes	Yes	No	No	9	8
190	2x40	8x49	Shared	100	100	Yes	Yes	No	Yes	9	6
191	2x42	3x46	Shared	100	33.3333	Yes	Yes	No	No	8	9
192	2x45	3x42	Shared	100	100	No	No	No	No	9	8
193	2x45	4x46	Shared	100	100	No	No	No	No	9	8
194	2x45	4x50	Shared	100	100	No	No	Yes	Yes	9	9
195	2x46	3x42	Shared	100	100	Yes	Yes	No	No	9	8
196	2x50	7x46	Shared	100	100	No	Yes	No	No	9	9
197	2x50	7x49	Shared	100	100	No	Yes	Yes	No	9	9
198	2x57	Lig	Shared	100	100	Yes	No	Yes	Yes	7	0
199	2x59	2x63	Shared	100	100	No	No	No	No	7	3
200	2x60	3x28	Shared	100	100	No	No	Yes	No	4	6
201	2x61	2x65	Shared	100	100	Yes	Yes	No	Yes	5	4
202	2x63	E1.R182	Shared	100	100	No	No	No	No	3	4
203	2x64	2x65	Shared	100	100	No	Yes	No	Yes	4	4
204	2x66	E1.F180	Shared	100	100	No	No	No	No	4	4
205	3x24	E1.D184	Shared	100	100	No	No	No	No	5	2
206	3x21	3x24	Shared	100	100	No	No	No	No	7	5
207	3x22	3x23	Shared	100	100	No	Yes	No	No	3	1
208	3x22	E2.E258	Shared	100	100	No	Yes	Yes	No	3	1
209	3x22	E2.H270	Shared	100	100	No	Yes	Yes	Yes	3	3
210	3x25	E2.P269	Shared	100	100	Yes	Yes	No	No	9	3
211	3x25	E2.H270	Shared	100	100	Yes	Yes	Yes	Yes	9	3
212	3x26	4x61	Shared	100	100	No	No	No	No	5	5
213	3x26	E2.N256	Shared	100	100	No	No	No	Yes	5	6
214	3x29	E2.I271	Shared	100	100	No	No	No	No	4	3
215	3x32	Lig	Shared	100	100	No	Yes	Yes	Yes	7	0
216	3x33	5x43	Shared	100	100	No	No	Yes	Yes	6	6
217	3x37	5x43	Shared	100	100	No	No	Yes	Yes	6	6
218	3x38	4x50	Shared	100	100	No	No	Yes	Yes	7	9
219	3x40	5x50	Shared	100	66.6667	No	No	No	No	7	8
220	3x41	4x49	Shared	100	100	No	No	No	No	5	6
221	3x44	3x48	Shared	100	100	No	Yes	No	No	7	7
222	3x44	5x50	Shared	100	100	No	Yes	No	No	7	8
223	3x45	4x49	Shared	100	33.3333	No	No	No	No	6	6
224	3x49	I2x53	Shared	100	100	Yes	No	Yes	Yes	9	7
225	3x51	3x55	Shared	100	100	No	No	No	No	8	6
226	3x51	5x60	Shared	100	100	No	No	No	Yes	8	4
227	3x52	I2x53	Shared	100	33.3333	No	No	Yes	Yes	5	7
228	3x52	I2x56	Shared	100	33.3333	No	No	No	No	5	4
229	3x53	I2x53	Shared	100	100	No	No	Yes	Yes	8	7
230	3x54	5x64	Shared	100	100	No	No	Yes	No	9	5
231	3x55	3x56	Shared	100	100	No	No	Yes	No	6	5
232	3x56	I2x52	Shared	100	0	Yes	No	No	No	5	5
233	I2x53	I2x57	Shared	100	100	Yes	Yes	Yes	No	7	6
234	4x38	4x40	Shared	100	100	No	No	No	No	8	4
235	4x38	4x41	Shared	100	100	No	No	No	No	8	5
236	4x59	E2.W255	Shared	100	100	No	No	Yes	Yes	5	5
237	4x60	5x39	Shared	100	100	No	No	No	Yes	6	7
238	5x36	E2.W255	Shared	100	100	Yes	Yes	Yes	Yes	5	5
239	5x39	E2.W255	Shared	100	100	No	Yes	Yes	Yes	7	5
240	E2.E258	E2.N256	Shared	100	100	Yes	No	No	Yes	1	6
241	E2.K259	E2.N256	Shared	100	33.3333	No	No	No	Yes	4	6
242	E2.C257	E2.C264	Shared	100	100	No	No	No	No	9	9
243	E2.E258	E2.H270	Shared	100	100	Yes	No	Yes	Yes	1	3
244	5x36	E2.S262	Shared	100	100	Yes	Yes	No	No	5	3
245	5x37	E2.V263	Shared	100	100	No	No	No	No	3	4
246	6x58	E2.D266	Shared	100	100	Yes	No	No	Yes	4	4
247	E2.D266	E3.K370	Shared	100	100	No	Yes	No	No	4	1
248	E2.F268	E2.I267	Shared	100	100	Yes	Yes	Yes	No	5	4
249	6x58	E2.I267	Shared	100	100	Yes	No	Yes	No	4	4
250	7x34	E2.I267	Shared	100	100	Yes	Yes	Yes	No	4	4
251	E2.F268	Lig	Shared	100	100	Yes	Yes	Yes	Yes	5	0
252	E2.H270	E2.P269	Shared	100	100	Yes	Yes	No	No	3	3
253	5x36	5x38	Shared	100	100	Yes	Yes	No	No	5	5
254	5x41	6x59	Shared	100	100	No	No	Yes	Yes	4	4
255	5x42	5x46	Shared	100	100	No	No	No	No	6	6
256	5x43	5x47	Shared	100	100	Yes	Yes	No	No	6	8
257	5x55	6x41	Shared	100	100	No	No	No	No	5	8
258	5x58	6x37	Shared	100	100	Yes	Yes	No	No	9	8
259	5x58	6x41	Shared	100	100	Yes	Yes	No	No	9	8
260	5x60	5x64	Shared	100	100	No	Yes	Yes	No	4	5
261	6x36	7x56	Shared	100	100	No	No	No	No	8	7
262	6x39	7x52	Shared	100	100	No	No	No	Yes	7	9
263	6x40	7x52	Shared	100	100	No	No	No	Yes	8	9
264	6x47	7x45	Shared	100	100	No	No	Yes	No	8	9
265	6x48	7x41	Shared	100	100	Yes	Yes	No	No	8	7
266	6x48	7x45	Shared	100	100	Yes	Yes	Yes	No	8	9
267	6x49	6x50	Shared	100	100	No	No	No	No	5	9
268	6x51	7x34	Shared	100	100	Yes	No	Yes	Yes	7	4
269	6x54	7x34	Shared	100	100	No	No	Yes	Yes	4	4
270	6x57	7x30	Shared	100	100	No	No	Yes	No	4	3
271	6x58	E3.M371	Shared	100	100	Yes	No	No	Yes	4	1
272	7x38	Lig	Shared	100	100	No	No	Yes	Yes	6	0
273	7x45	7x49	Shared	100	100	Yes	No	Yes	No	9	9
274	8x48	8x51	Shared	100	33.3333	No	No	No	No	5	8
275	1x28	1x31	Shared	100	100	Yes	No	No	No	6	2
276	1x57	I1x50	Shared	100	100	No	No	No	Yes	7	9
277	6x57	E3.K370	Shared	100	100	No	No	No	No	4	1
278	3x37	4x53	Shared	50	66.6667	No	No	No	No	6	8
279	1x56	8x54	Shared	50	66.6667	Yes	No	No	No	8	7
280	3x45	4x45	Shared	50	0	No	No	No	No	6	5
281	4x56	5x42	Shared	50	100	No	No	No	No	5	6
282	6x42	6x46	Shared	0	33.3333	No	No	No	No	6	5
283	2x52	3x35	Shared	0	33.3333	No	No	No	No	6	7
284	7x43	7x47	Shared	0	33.3333	No	No	Yes	Yes	5	7
285	5x45	5x48	Shared	50	33.3333	No	No	No	No	3	5
286	1x49	7x51	Shared	0	100	Yes	No	No	No	8	6
287	3x30	3x33	Shared	50	100	No	No	No	No	6	6
288	3x44	5x53	Shared	50	100	No	Yes	No	No	7	6
289	2x37	I1x49	Shared	50	33.3333	Yes	No	No	No	5	5
290	6x59	6x60	Shared	50	100	Yes	Yes	No	No	4	5
291	2x49	4x50	Shared	0	33.3333	No	No	Yes	Yes	8	9
292	6x35	7x56	Shared	50	0	No	No	No	No	7	7
293	2x56	3x32	Shared	0	66.6667	No	No	No	Yes	5	7
294	5x44	6x56	Shared	0	33.3333	No	Yes	No	No	5	6
295	1x28	1x30	Shared	50	100	Yes	No	No	No	6	5
296	2x39	3x49	Shared	50	100	No	No	Yes	No	8	9
297	3x30	3x31	Shared	0	0	No	No	No	No	6	4
298	8x52	8x56	Shared	50	0	No	No	No	No	4	3
299	5x66	5x70	Shared	50	100	No	No	No	No	5	5
300	5x56	5x60	Shared	50	100	No	No	No	Yes	4	4
301	3x31	3x34	Shared	0	0	No	No	No	No	4	5
302	2x53	3x35	Shared	50	100	No	No	No	No	8	7
303	5x44	5x45	Shared	0	33.3333	No	Yes	No	No	5	3
304	6x38	6x42	Shared	0	0	No	No	No	No	6	6
305	5x62	6x34	Shared	50	33.3333	No	No	No	No	6	7
306	3x56	I2x50	Shared	0	33.3333	Yes	No	No	No	5	8
307	4x39	4x40	Shared	0	0	No	Yes	No	No	1	4
308	7x51	7x55	Shared	0	100	No	No	No	No	6	5
309	NT.C107	NT.F108	Shared	0	33.3333	No	No	Yes	No	2	5
310	4x39	I1.C149	Shared	0	33.3333	No	Yes	No	No	1	7
311	1x54	1x58	Shared	0	0	No	No	No	No	7	4
312	3x27	4x61	Shared	0	100	No	No	No	No	5	5
313	I2x53	I2x54	Shared	0	33.3333	Yes	Yes	No	No	7	4
314	1x37	1x41	Shared	0	33.3333	No	No	No	No	4	4
315	5x64	5x67	Shared	0	33.3333	Yes	No	No	No	5	5
316	4x51	4x52	Shared	0	33.3333	No	No	No	Yes	4	5
317	1x56	8x57	Shared	0	33.3333	Yes	No	No	No	8	5
318	8x48	8x49	Shared	0	100	No	No	No	Yes	5	6
319	NT.C107	NT.D104	cb1_on	0	100	No	No	No	No	2	6
320	E1.K183	NT.I105	cb1_on	0	100	No	No	No	No	6	3
321	E2.P269	NT.F108	cb1_on	0	100	No	No	Yes	No	3	5
322	2x64	NT.M109	cb1_on	0	100	No	Yes	Yes	No	4	3
323	7x31	NT.V110	cb1_on	0	100	No	No	No	No	2	3
324	1x32	NT.L111	cb1_on	0	100	No	No	No	Yes	4	4
325	1x31	7x36	cb1_on	0	100	No	No	No	No	2	4
326	1x35	2x61	cb1_on	0	100	No	No	Yes	Yes	5	5
327	1x35	7x36	cb1_on	0	100	No	No	No	No	5	4
328	1x35	7x39	cb1_on	0	100	No	No	No	No	5	5
329	1x38	7x39	cb1_on	0	100	No	No	No	No	5	5
330	1x43	1x46	cb1_on	0	100	No	No	Yes	Yes	6	7
331	1x46	7x46	cb1_on	0	100	Yes	Yes	No	No	7	9
332	1x47	2x51	cb1_on	0	100	No	No	No	No	6	7
333	1x50	2x47	cb1_on	0	100	No	No	No	No	9	9
334	1x53	7x54	cb1_on	0	100	No	No	No	No	9	7
335	1x54	2x47	cb1_on	0	100	No	No	No	No	7	9
336	1x55	1x56	cb1_on	0	100	No	No	Yes	No	4	8
337	1x57	2x40	cb1_on	0	100	No	No	Yes	Yes	7	9
338	2x38	4x39	cb1_on	0	100	No	No	No	Yes	5	1
339	2x40	8x50	cb1_on	0	100	Yes	Yes	No	No	9	8
340	2x42	3x45	cb1_on	0	100	Yes	Yes	No	No	8	6
341	2x46	2x50	cb1_on	0	100	Yes	Yes	No	Yes	9	9
342	2x46	3x43	cb1_on	0	100	Yes	Yes	No	No	9	8
343	2x46	7x49	cb1_on	0	100	Yes	Yes	Yes	No	9	9
344	2x50	3x39	cb1_on	0	100	No	Yes	No	No	9	9
345	2x57	2x61	cb1_on	0	100	Yes	No	Yes	Yes	7	5
346	2x60	Lig	cb1_on	0	100	No	No	Yes	Yes	4	0
347	2x61	Lig	cb1_on	0	100	Yes	Yes	Yes	Yes	5	0
348	2x64	Lig	cb1_on	0	100	No	Yes	Yes	Yes	4	0
349	2x65	Lig	cb1_on	0	100	No	Yes	Yes	Yes	4	0
350	3x25	E1.D184	cb1_on	0	100	Yes	Yes	No	No	9	2
351	3x21	3x23	cb1_on	0	100	No	No	No	No	7	1
352	3x23	3x24	cb1_on	0	100	No	No	No	No	1	5
353	3x26	4x60	cb1_on	0	100	No	No	No	No	5	6
354	3x29	Lig	cb1_on	0	100	No	No	Yes	Yes	4	0
355	3x32	3x36	cb1_on	0	100	No	Yes	Yes	No	7	7
356	3x33	Lig	cb1_on	0	100	No	No	Yes	Yes	6	0
357	3x36	7x41	cb1_on	0	100	Yes	No	No	No	7	7
358	3x36	Lig	cb1_on	0	100	Yes	No	Yes	Yes	7	0
359	3x43	7x53	cb1_on	0	100	No	No	Yes	Yes	8	9
360	3x46	3x50	cb1_on	0	100	No	No	Yes	No	9	9
361	3x47	5x54	cb1_on	0	100	No	No	No	No	8	8
362	3x50	5x58	cb1_on	0	100	Yes	No	Yes	Yes	9	9
363	3x50	7x53	cb1_on	0	100	Yes	No	Yes	Yes	9	9
364	3x54	5x61	cb1_on	0	100	No	No	No	No	9	9
365	3x55	5x60	cb1_on	0	100	No	No	No	Yes	6	4
366	4x46	4x50	cb1_on	0	100	No	No	Yes	Yes	8	9
367	4x48	4x52	cb1_on	0	100	No	No	No	Yes	3	5
368	4x59	4x60	cb1_on	0	100	No	No	No	No	5	6
369	4x63	E2.W255	cb1_on	0	100	No	No	Yes	Yes	5	5
370	5x36	E2.C257	cb1_on	0	100	Yes	Yes	No	No	5	9
371	5x37	E2.S265	cb1_on	0	100	No	No	No	No	3	4
372	E2.D266	E3.M371	cb1_on	0	100	No	Yes	No	Yes	4	1
373	E2.F268	E2.I271	cb1_on	0	100	Yes	Yes	No	No	5	3
374	7x34	E2.F268	cb1_on	0	100	Yes	Yes	Yes	Yes	4	5
375	5x39	Lig	cb1_on	0	100	No	Yes	Yes	Yes	7	0
376	5x40	5x44	cb1_on	0	100	No	No	No	Yes	5	5
377	5x43	6x48	cb1_on	0	100	Yes	Yes	Yes	Yes	6	8
378	5x43	6x55	cb1_on	0	100	Yes	Yes	No	No	6	6
379	5x43	Lig	cb1_on	0	100	Yes	Yes	Yes	Yes	6	0
380	5x44	6x52	cb1_on	0	100	No	Yes	No	No	5	7
381	5x44	6x55	cb1_on	0	100	No	Yes	No	No	5	6
382	5x47	5x51	cb1_on	0	100	No	No	No	No	8	6
383	5x51	6x44	cb1_on	0	100	No	No	No	No	6	9
384	5x51	6x48	cb1_on	0	100	No	No	Yes	Yes	6	8
385	5x58	6x40	cb1_on	0	100	Yes	Yes	No	No	9	8
386	5x58	7x53	cb1_on	0	100	Yes	Yes	Yes	Yes	9	9
387	5x60	5x63	cb1_on	0	100	No	Yes	No	No	4	3
388	5x62	6x37	cb1_on	0	100	No	No	No	No	6	8
389	5x66	6x30	cb1_on	0	100	No	No	No	Yes	5	7
390	5x69	6x30	cb1_on	0	100	No	No	No	Yes	5	7
391	6x28	6x32	cb1_on	0	100	No	No	No	No	4	7
392	6x40	7x53	cb1_on	0	100	No	No	Yes	Yes	8	9
393	6x43	7x52	cb1_on	0	100	No	No	No	Yes	6	9
394	6x54	7x37	cb1_on	0	100	No	No	No	No	4	5
395	6x55	7x34	cb1_on	0	100	No	No	Yes	Yes	6	4
396	7x30	E3.M371	cb1_on	0	100	Yes	No	No	Yes	3	1
397	7x34	Lig	cb1_on	0	100	Yes	Yes	Yes	Yes	4	0
398	7x52	7x53	cb1_on	0	100	No	Yes	Yes	Yes	9	9
399	8x47	8x49	cb1_on	0	100	No	No	No	Yes	8	6
400	8x52	8x55	cb1_on	0	100	No	No	No	No	4	5
401	2x65	NT.L111	cb1_on	0	100	No	Yes	No	Yes	4	4
402	8x50	I1x50	cb1_on	0	100	No	No	No	Yes	8	9
403	4x39	I1x51	cb1_on	0	100	No	Yes	No	Yes	1	8
404	2x57	3x32	cb1_on	0	100	Yes	No	No	Yes	7	7
405	2x61	7x38	cb1_on	0	100	Yes	Yes	No	No	5	6
406	2x64	E1.H181	cb1_on	0	100	No	Yes	No	No	4	3
407	3x22	E2.N256	cb1_on	0	100	No	Yes	No	Yes	3	6
408	3x25	3x29	cb1_on	0	100	Yes	Yes	No	No	9	4
409	7x31	E2.D266	cb1_on	0	100	No	No	No	Yes	2	4
410	5x68	5x72	cb1_on	0	100	No	No	No	No	7	0
411	6x30	6x31	cb1_on	0	100	No	Yes	Yes	No	7	5
412	6x48	6x51	cb1_on	0	100	Yes	Yes	Yes	No	8	7
413	6x48	6x52	cb1_on	0	100	Yes	Yes	No	No	8	7
414	7x55	7x56	cb1_on	0	100	No	No	No	No	5	7
415	1x59	I1x48	cb1_on	0	100	No	No	No	No	5	6
416	1x60	I1x51	cb1_on	0	100	No	No	No	Yes	6	8
417	2x64	E1.R182	cb1_on	0	100	No	Yes	No	No	4	4
418	6x57	6x59	cb1_on	0	100	No	No	Yes	Yes	4	4
419	6x59	E3.M371	cb1_on	0	100	Yes	Yes	No	Yes	4	1
420	3x51	5x57	cb1_on	0	33.3333	No	No	No	No	8	7
421	7x54	8x50	cb1_on	0	66.6667	No	No	No	No	7	8
422	2x54	7x42	cb1_on	0	66.6667	No	Yes	No	No	7	7
423	4x58	4x61	cb1_on	0	66.6667	No	No	No	No	5	5
424	4x49	4x52	cb1_on	0	66.6667	No	No	No	Yes	6	5
425	5x58	5x61	cb1_on	0	33.3333	Yes	Yes	No	No	9	9
426	5x39	5x42	cb1_on	0	33.3333	No	Yes	No	No	7	6
427	2x42	3x49	cb1_on	0	66.6667	Yes	Yes	Yes	No	8	9
428	1x32	2x66	cb1_on	0	33.3333	No	No	No	No	4	4
429	2x52	2x56	cb1_on	0	33.3333	No	No	No	No	6	5
430	7x27	7x28	cb1_on	0	66.6667	No	No	No	No	1	3
431	7x27	E3.K370	cb1_on	0	33.3333	No	No	No	No	1	1
432	1x42	7x42	cb1_on	0	33.3333	No	No	No	No	6	7
433	7x27	7x29	cb1_on	0	33.3333	No	No	No	No	1	4
434	2x41	I1x51	cb1_on	0	66.6667	No	No	No	Yes	3	8
435	5x37	E2.D266	cb1_on	0	33.3333	No	No	No	Yes	3	4
436	8x48	8x52	cb1_on	0	33.3333	No	No	No	No	5	4
437	3x34	4x54	cb1_on	0	33.3333	No	No	No	No	5	4
438	6x43	7x48	cb1_on	0	33.3333	No	No	No	No	6	6
439	3x44	5x54	cb1_on	0	33.3333	No	Yes	No	No	7	8
440	1x39	2x62	cb1_on	0	66.6667	Yes	No	No	No	7	5
441	1x39	7x39	cb1_on	0	66.6667	Yes	No	No	No	7	5
442	3x40	6x48	cb1_on	0	33.3333	No	No	Yes	Yes	7	8
443	1x52	8x54	cb1_on	0	33.3333	No	No	No	No	7	7
444	7x28	7x32	cb1_on	0	33.3333	No	No	No	No	3	1
445	1x57	2x43	cb1_on	0	66.6667	No	No	No	No	7	8
446	2x44	2x47	cb1_on	0	0	No	No	No	No	6	9
447	I1.C149	I1x48	cb1_on	0	33.3333	No	No	No	No	7	6
448	2x42	4x42	cb1_on	0	33.3333	Yes	Yes	No	No	8	7
449	2x63	E1.K183	cb1_on	0	33.3333	No	No	No	No	3	6
450	3x34	4x57	cb1_on	0	0	No	No	No	No	5	7
451	5x68	6x29	cb1_on	0	33.3333	No	No	No	No	7	6
452	I2x50	I2x51	cb1_on	0	33.3333	No	No	No	No	8	7
453	2x54	2x55	cb1_on	0	33.3333	No	Yes	No	No	7	4
454	5x69	6x29	cb1_on	0	33.3333	No	No	No	No	5	6
455	5x65	6x33	cb1_on	0	0	No	No	No	No	8	8
456	6x27	6x30	cb1_on	0	33.3333	No	No	No	Yes	4	7
457	2x58	2x62	cb1_on	0	33.3333	No	No	No	No	7	5
458	1x39	1x40	cb1_on	0	33.3333	Yes	No	No	No	7	3
459	1x41	1x42	cb1_on	0	33.3333	No	No	No	No	4	6
460	5x61	6x33	cb1_on	0	0	No	No	No	No	9	8
461	1x32	1x33	cb1_on	0	33.3333	No	No	No	No	4	5
462	4x43	4x46	cb1_on	0	33.3333	No	No	No	No	1	8
463	1x45	7x47	cb1_on	0	0	No	No	Yes	Yes	4	7
464	6x61	E3.M371	cb1_on	0	33.3333	No	No	No	Yes	3	1
465	E2.L260	E2.W255	cb1_on	0	33.3333	No	No	Yes	Yes	3	5
466	6x50	7x40	cb1_on	0	0	No	No	No	No	9	7
467	1x36	2x62	cb1_on	0	33.3333	No	No	No	No	5	5
468	5x65	6x30	cb1_on	0	0	No	No	No	Yes	8	7
469	6x54	7x33	cb1_on	0	0	No	No	No	No	4	4
470	5x72	I3.T313	cb1_on	0	33.3333	No	No	No	No	0	0
471	5x75	5x76	cb1_on	0	0	No	No	No	No	0	0
472	5x59	6x41	cb1_on	0	0	No	No	No	No	3	8
473	6x51	7x40	cb1_on	0	0	Yes	No	No	No	7	7
474	5x67	5x71	cb1_on	0	0	No	No	No	No	5	0
475	NT.D104	NT.E106	cb1_on	0	33.3333	No	No	No	No	6	4
476	6x28	6x31	cb1_on	0	33.3333	No	No	Yes	No	4	5
477	I2x55	I2x56	cb1_on	0	0	No	No	No	No	4	4
478	5x45	5x49	cb1_on	0	0	No	No	No	No	3	6
479	5x76	I3.T313	cb1_on	0	0	No	No	No	No	0	0
480	4x62	4x63	cb1_on	0	0	No	No	No	No	5	5
481	4x47	4x51	cb1_on	0	0	No	No	No	No	4	4
482	6x46	6x47	cb1_on	0	0	No	No	No	No	5	8
483	5x73	6x27	cb1_on	0	0	No	No	No	No	0	4
484	1x34	1x38	cb1_on	0	0	No	No	No	No	5	5
485	7x35	NT.L111	cb1_on	0	0	No	No	No	Yes	4	4
486	5x55	6x45	cb1_on	0	0	No	No	No	No	5	6
487	4x52	4x55	cb1_on	0	0	No	Yes	No	No	5	3
488	4x41	4x44	cb1_on	0	0	No	No	No	No	5	3

Orange: nodes, hubs and links specific of cb1_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of cb1_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	cb1_off Avg Int. Strength	cb1_on Avg Int. Strength	cb1_off Num Of Links	cb1_on Num Of Links	ConSurf
1	NT.N101	cb1_off	50	0	4	0	6
2	NT.F102	cb1_off	100	0	5	0	5
3	NT.M103	cb1_off	100	0	5	0	4
4	NT.F108	cb1_off	50	33.3333	5	2	5
5	NT.M109	cb1_off	0	0	4	1	3
6	1x28	cb1_off	0	0	5	3	6
7	1x39	cb1_off	0	33.3333	4	3	7
8	1x49	cb1_off	0	0	5	3	8
9	1x56	cb1_off	0	33.3333	4	3	8
10	2x37	cb1_off	0	0	4	3	5
11	2x57	cb1_off	100	66.6667	6	3	7
12	3x28	cb1_off	50	0	5	1	6
13	3x36	cb1_off	100	66.6667	6	3	7
14	3x49	cb1_off	50	33.3333	4	3	9
15	3x50	cb1_off	100	0	6	3	9
16	3x56	cb1_off	0	0	4	3	5
17	I2x57	cb1_off	50	33.3333	4	2	6
18	E2.E258	cb1_off	100	0	5	3	1
19	E2.I267	cb1_off	100	66.6667	4	3	4
20	5x64	cb1_off	0	0	4	3	5
21	6x31	cb1_off	0	0	4	2	5
22	6x51	cb1_off	50	0	4	3	7
23	6x58	cb1_off	50	0	4	3	4
24	7x30	cb1_off	0	0	4	2	3
25	7x45	cb1_off	100	0	5	3	9
26	7x49	cb1_off	50	33.3333	4	3	9
27	1x46	Shared	0	33.3333	4	4	7
28	2x40	Shared	100	100	5	7	9
29	2x42	Shared	50	33.3333	4	4	8
30	2x46	Shared	0	33.3333	4	4	9
31	2x61	Shared	50	100	5	5	5
32	3x25	Shared	100	66.6667	4	4	9
33	I2x53	Shared	100	33.3333	6	5	7
34	4x50	Shared	100	33.3333	6	4	9
35	E2.W255	Shared	100	33.3333	4	5	5
36	E2.F268	Shared	100	66.6667	4	4	5
37	E2.H270	Shared	100	0	5	4	3
38	5x36	Shared	0	33.3333	4	4	5
39	5x43	Shared	100	100	6	6	6
40	5x58	Shared	50	100	6	6	9
41	6x48	Shared	100	100	4	7	8
42	6x59	Shared	0	0	4	4	4
43	7x34	Shared	100	66.6667	4	6	4
44	7x47	Shared	0	0	5	4	7
45	7x53	Shared	50	66.6667	4	5	9
46	Lig	Shared	100	100	12	14	0
47	NT.L111	cb1_on	50	0	3	4	4
48	I1x50	cb1_on	0	66.6667	3	4	9
49	I1x51	cb1_on	0	0	2	4	8
50	2x50	cb1_on	0	66.6667	3	5	9
51	2x54	cb1_on	0	0	2	4	7
52	2x64	cb1_on	0	33.3333	3	5	4
53	2x65	cb1_on	0	66.6667	2	4	4
54	3x22	cb1_on	0	33.3333	3	4	3
55	3x32	cb1_on	0	0	2	4	7
56	3x44	cb1_on	0	66.6667	3	4	7
57	4x39	cb1_on	0	0	3	4	1
58	4x52	cb1_on	0	0	2	4	5
59	E2.N256	cb1_on	0	0	3	4	6
60	E2.D266	cb1_on	0	0	2	5	4
61	5x39	cb1_on	50	33.3333	3	4	7
62	5x44	cb1_on	0	66.6667	3	5	5
63	5x60	cb1_on	50	100	3	5	4
64	6x30	cb1_on	0	33.3333	3	5	7
65	E3.M371	cb1_on	0	0	2	5	1
66	7x52	cb1_on	0	66.6667	2	4	9
67	8x49	cb1_on	0	33.3333	3	4	6

Orange: nodes, hubs and links specific of cb1_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of cb1_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	cb1_off Recurrence	cb1_on Recurrence	cb1_off Hub1?	cb1_on Hub1?	cb1_off Hub2?	cb1_on Hub2?	ConSurf1	ConSurf2
1	3x28	NT.F102	cb1_off	12.6569	0	Yes	No	Yes	No	6	5
2	3x25	NT.F102	cb1_off	16.8477	0	Yes	Yes	Yes	No	9	5
3	2x57	Lig	cb1_off	11.441	1.11799	Yes	No	Yes	Yes	7	0
4	Lig	NT.F102	cb1_off	26.581	0	Yes	Yes	Yes	No	0	5
5	Lig	NT.I105	cb1_off	12.8711	0	Yes	Yes	No	No	0	3
6	NT.E106	NT.I105	cb1_off	12.1108	0	No	No	No	No	4	3
7	NT.E106	NT.L111	cb1_off	11.1725	0	No	No	No	Yes	4	4
8	1x46	1x49	cb1_off	10.1798	0	Yes	Yes	Yes	No	7	8
9	1x46	7x42	cb1_off	13.6344	0	Yes	Yes	No	No	7	7
10	2x57	7x42	cb1_off	13.7038	0	Yes	No	No	No	7	7
11	1x49	7x50	cb1_off	14.4249	7.19863	Yes	No	No	No	8	9
12	6x48	7x41	cb1_off	74.2699	5.44058	Yes	Yes	No	No	8	7
13	7x41	Lig	cb1_off	57.4674	0	No	No	Yes	Yes	7	0
14	1x53	7x50	cb1_off	13.1909	0	No	No	No	No	9	9
15	2x45	4x50	cb1_off	13.8909	3.91295	No	No	Yes	Yes	9	9
16	2x45	3x42	cb1_off	23.5789	7.80457	No	No	No	No	9	8
17	2x46	3x42	cb1_off	24.7405	9.07617	Yes	Yes	No	No	9	8
18	2x46	7x53	cb1_off	39.6603	0	Yes	Yes	Yes	Yes	9	9
19	7x49	7x53	cb1_off	97.7884	0	Yes	No	Yes	Yes	9	9
20	8x47	8x50	cb1_off	11.0246	0	No	No	No	No	8	8
21	2x40	8x47	cb1_off	12.0474	1.16066	Yes	Yes	No	No	9	8
22	1x57	I1x50	cb1_off	62.2767	0.179219	No	No	No	Yes	7	9
23	1x57	2x44	cb1_off	62.8047	0	No	No	No	No	7	6
24	2x43	2x44	cb1_off	63.5258	0	No	No	No	No	8	6
25	2x43	7x53	cb1_off	73.2048	0	No	No	Yes	Yes	8	9
26	3x49	I2x57	cb1_off	19.1739	0	Yes	No	Yes	No	9	6
27	2x42	2x43	cb1_off	26.587	0	Yes	Yes	No	No	8	8
28	2x42	2x46	cb1_off	23.1324	0	Yes	Yes	Yes	Yes	8	9
29	3x36	5x43	cb1_off	38.8064	0	Yes	No	Yes	Yes	7	6
30	3x36	6x48	cb1_off	37.1862	0	Yes	No	Yes	Yes	7	8
31	3x36	3x40	cb1_off	12.3461	0	Yes	No	No	No	7	7
32	5x58	6x37	cb1_off	38.6857	3.98976	Yes	Yes	No	No	9	8
33	2x42	6x37	cb1_off	40.0525	0	Yes	Yes	No	No	8	8
34	3x51	3x55	cb1_off	18.4045	0.0384041	No	No	No	No	8	6
35	3x55	3x56	cb1_off	20.4894	5.30403	No	No	Yes	No	6	5
36	3x56	I2x56	cb1_off	28.7684	0	Yes	No	No	No	5	4
37	3x52	I2x56	cb1_off	30.8231	2.58161	No	No	No	No	5	4
38	3x52	I2x53	cb1_off	16.6697	3.86175	No	No	Yes	Yes	5	7
39	3x52	I2x57	cb1_off	16.199	0	No	No	Yes	No	5	6
40	3x51	5x60	cb1_off	16.3137	2.62428	No	No	No	Yes	8	4
41	5x39	5x43	cb1_off	21.4669	0	No	Yes	Yes	Yes	7	6
42	5x66	6x31	cb1_off	15.5081	0	No	No	Yes	No	5	5
43	5x62	5x66	cb1_off	18.4951	0	No	No	No	No	6	5
44	5x62	6x38	cb1_off	21.9889	0	No	No	No	No	6	6
45	5x58	6x38	cb1_off	27.1874	0	Yes	Yes	No	No	9	6
46	1x53	7x53	cb1_off	14.1474	0	No	No	Yes	Yes	9	9
47	6x44	7x45	cb1_off	21.3885	0	No	No	Yes	No	9	9
48	3x36	6x44	cb1_off	20.951	0	Yes	No	No	No	7	9
49	6x51	7x41	cb1_off	16.5792	0	Yes	No	No	No	7	7
50	7x45	7x49	Shared	100	100	Yes	No	Yes	No	9	9
51	6x48	7x45	Shared	78.7443	99.7866	Yes	Yes	Yes	No	8	9
52	2x40	I1x50	Shared	61.5979	13.578	Yes	Yes	No	Yes	9	9
53	2x39	2x40	Shared	46.9255	28.8713	No	No	Yes	Yes	8	9
54	2x39	3x49	Shared	46.8773	29.8571	No	No	Yes	No	8	9
55	E2.F268	Lig	Shared	15.3482	10.0405	Yes	Yes	Yes	Yes	5	0
56	3x49	I2x53	Shared	20.1515	32.4899	Yes	No	Yes	Yes	9	7
57	5x60	5x64	Shared	12.1138	13.0019	No	Yes	Yes	No	4	5
58	5x39	E2.W255	Shared	18.4377	13.2281	No	Yes	Yes	Yes	7	5
59	6x58	E2.I267	Shared	11.2931	34.2266	Yes	No	Yes	No	4	4
60	6x51	7x34	Shared	14.6573	22.2872	Yes	No	Yes	Yes	7	4
61	2x64	Lig	cb1_on	0	10.2496	No	Yes	Yes	Yes	4	0
62	3x29	Lig	cb1_on	0	18.7796	No	No	Yes	Yes	4	0
63	3x25	3x29	cb1_on	0	18.2291	Yes	Yes	No	No	9	4
64	6x58	E2.D266	cb1_on	4.65846	19.5776	Yes	No	No	Yes	4	4
65	7x34	E2.I267	cb1_on	4.32959	26.0038	Yes	Yes	Yes	No	4	4
66	7x34	Lig	cb1_on	0	13.0062	Yes	Yes	Yes	Yes	4	0
67	2x65	NT.L111	cb1_on	0	13.7487	No	Yes	No	Yes	4	4
68	2x65	Lig	cb1_on	0	14.0132	No	Yes	Yes	Yes	4	0
69	1x35	2x61	cb1_on	0	14.0772	No	No	Yes	Yes	5	5
70	2x61	Lig	cb1_on	0	14.1583	Yes	Yes	Yes	Yes	5	0
71	1x35	7x39	cb1_on	0	11.6194	No	No	No	No	5	5
72	1x46	7x46	cb1_on	0	17.269	Yes	Yes	No	No	7	9
73	2x50	7x46	cb1_on	1.17367	18.4212	No	Yes	No	No	9	9
74	2x50	7x49	cb1_on	4.8244	19.4709	No	Yes	Yes	No	9	9
75	5x43	6x48	cb1_on	0	65.0139	Yes	Yes	Yes	Yes	6	8
76	5x43	Lig	cb1_on	0	61.8135	Yes	Yes	Yes	Yes	6	0
77	1x46	2x54	cb1_on	5.80497	11.5938	Yes	Yes	No	Yes	7	7
78	1x50	2x50	cb1_on	2.77878	15.6475	No	No	No	Yes	9	9
79	2x42	3x49	cb1_on	0	62.0098	Yes	Yes	Yes	No	8	9
80	2x42	3x46	cb1_on	1.49047	70.6123	Yes	Yes	No	No	8	9
81	3x46	3x50	cb1_on	0	71.342	No	No	Yes	No	9	9
82	3x50	7x53	cb1_on	0	59.7269	Yes	No	Yes	Yes	9	9
83	3x43	7x53	cb1_on	0	94.0815	No	No	Yes	Yes	8	9
84	2x46	3x43	cb1_on	0	94.4613	Yes	Yes	No	No	9	8
85	2x46	7x49	cb1_on	0	80.5419	Yes	Yes	Yes	No	9	9
86	1x56	8x57	cb1_on	5.49722	13.8724	Yes	No	No	No	8	5
87	1x59	8x57	cb1_on	3.40937	16.6588	No	No	No	No	5	5
88	1x59	I1x48	cb1_on	0	20.0981	No	No	No	No	5	6
89	I1x48	I1x51	cb1_on	3.84082	15.831	No	No	No	Yes	6	8
90	4x39	I1x51	cb1_on	0	10.6465	No	Yes	No	Yes	1	8
91	2x38	4x39	cb1_on	0	24.3226	No	No	No	Yes	5	1
92	2x38	I2x57	cb1_on	2.2357	25.2998	No	No	Yes	No	5	6
93	I2x53	I2x57	cb1_on	0.1056	26.3793	Yes	Yes	Yes	No	7	6
94	1x60	I1x51	cb1_on	0	10.9452	No	No	No	Yes	6	8
95	1x60	I1x50	cb1_on	6.69201	12.8952	No	No	No	Yes	6	9
96	2x42	3x45	cb1_on	0	11.6322	Yes	Yes	No	No	8	6
97	4x60	5x39	cb1_on	1.58701	10.6038	No	No	No	Yes	6	7
98	5x39	Lig	cb1_on	0	27.5741	No	Yes	Yes	Yes	7	0
99	3x54	5x64	cb1_on	2.1301	16.501	No	No	Yes	No	9	5
100	3x54	5x61	cb1_on	0	17.5336	No	No	No	No	9	9
101	5x58	5x61	cb1_on	0	36.8167	Yes	Yes	No	No	9	9
102	5x58	7x53	cb1_on	0	32.1101	Yes	Yes	Yes	Yes	9	9
103	6x58	E3.M371	cb1_on	2.4469	13.0617	Yes	No	No	Yes	4	1
104	5x65	6x30	cb1_on	0	17.9176	No	No	No	Yes	8	7
105	5x65	6x33	cb1_on	0	19.1252	No	No	No	No	8	8
106	5x61	6x33	cb1_on	0	20.1067	No	No	No	No	9	8
107	E2.D266	E3.K370	cb1_on	2.41974	10.2283	No	Yes	No	No	4	1
108	6x48	6x51	cb1_on	0	23.6783	Yes	Yes	Yes	No	8	7
109	2x46	2x50	cb1_on	0	16.134	Yes	Yes	No	Yes	9	9
110	3x50	5x58	cb1_on	0	12.1314	Yes	No	Yes	Yes	9	9

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
2x64	NT.N101	cb1_off	13.29	0	0	1	1	2
E1.K183	NT.N101	cb1_off	6.295	0	0	0	2	2
NT.F102	NT.M103	cb1_off	4.975	0	1	0	1	1
2x60	NT.F102	cb1_off	5.28	0	1	0	1	1
3x25	NT.F102	cb1_off	6.965	0	1	2	2	1
3x28	NT.F102	cb1_off	9.31	0	1	0	2	1
Lig	NT.F102	cb1_off	4.39	0	1	1	0	1
2x57	NT.M103	cb1_off	6.84	0	1	1	1	1
2x60	NT.M103	cb1_off	6.135	0	1	0	1	1
2x61	NT.M103	cb1_off	3.735	0	0	1	1	1
Lig	NT.M103	cb1_off	11.44	0	1	1	0	1
2x64	NT.D104	cb1_off	9.555	0	0	1	1	2
NT.E106	NT.I105	cb1_off	4.1	0	0	0	2	1
Lig	NT.I105	cb1_off	10.315	0	1	1	0	1
1x39	2x57	cb1_off	3.965	0	1	0	1	1
1x39	2x61	cb1_off	4.625	0	1	0	1	1
1x39	Lig	cb1_off	3.975	0	1	0	1	0
1x40	2x61	cb1_off	6.09	0	0	0	2	1
2x57	7x42	cb1_off	11.57	0	1	1	1	2
2x57	Lig	Shared	12.285	8.51	1	1	1	0
2x60	3x28	Shared	7.65	7.65	1	0	1	2
2x61	2x65	Shared	16.4	6.79	0	1	1	1
2x64	2x65	Shared	10.75	10.5567	0	1	1	1
3x29	E2.F268	cb1_off	7.92	0	0	0	1	1
3x29	E2.I271	Shared	3.565	3.33	0	0	1	2
3x32	Lig	Shared	15.525	4.24667	0	1	1	0
3x33	5x43	Shared	10.915	3.64	0	1	1	1
3x36	3x40	cb1_off	6.555	0	1	1	1	2
3x36	5x43	cb1_off	5.515	0	1	1	1	1
3x36	5x47	cb1_off	6.505	0	1	1	1	2
3x36	6x44	cb1_off	4.87	0	1	1	1	2
3x36	6x48	cb1_off	29.565	0	1	1	1	2
3x36	6x52	cb1_off	4.26	0	1	1	1	2
3x37	5x43	Shared	6.065	4.85	0	0	2	1
4x60	5x39	Shared	19.47	6.48667	0	0	2	1
5x39	E2.W255	Shared	13.985	5.46667	0	0	1	2
E2.F268	E2.I267	Shared	10.05	6.69667	1	1	1	2
6x55	E2.I267	cb1_off	3.645	0	1	0	2	2
7x34	E2.I267	Shared	9.42	3.34667	0	1	1	2
6x55	E2.F268	cb1_off	4.975	0	1	0	2	1
E2.F268	Lig	Shared	7.07	14.27	1	1	1	0
5x43	5x44	cb1_off	5.285	0	1	1	1	2
5x43	5x47	Shared	6.11	9.33	1	1	1	2
6x48	7x41	Shared	18.28	4.35333	1	0	2	1
6x51	6x55	cb1_off	4.24	0	1	0	1	2
6x51	7x34	Shared	6.09	2.84333	1	0	1	1
6x51	7x41	cb1_off	4.76	0	1	0	1	1
6x51	Lig	cb1_off	4.705	0	1	0	1	0
6x54	7x34	Shared	6.91	7.95333	0	0	2	1
7x38	Lig	Shared	16.605	3.61667	0	1	1	0
7x39	Lig	cb1_off	8.28	0	0	0	1	0
7x41	Lig	cb1_off	4.71	0	1	0	1	0
NT.E106	NT.L111	cb1_off	5.3	0	0	0	2	2
7x34	NT.F108	cb1_off	5.36	0	0	1	1	2
5x42	E2.W255	cb1_off	4.01	0	0	0	2	2
6x44	6x48	cb1_off	3.415	0	1	0	2	2
1x43	2x57	cb1_off	3.01	0	0	0	2	1
1x36	2x61	cb1_off	2.77	0	0	0	2	1
3x30	3x33	Shared	2.73	3.03333	0	0	2	1
5x39	5x43	cb1_off	2.41	0	0	0	1	1
2x56	3x32	Shared	2.305	2.56	0	0	2	1
2x53	Lig	cb1_off	1.99	0	0	0	1	0
2x57	2x58	cb1_off	1.965	0	1	1	1	2
2x53	3x35	Shared	1.855	3.71	0	0	1	2
1x38	1x39	cb1_off	1.5	0	0	0	2	1
E1.K183	NT.I105	cb1_on	0	5.33	0	0	2	1
2x64	NT.M109	cb1_on	0	3.73	0	1	1	2
1x35	2x61	cb1_on	0	2.93333	0	0	2	1
1x35	7x39	cb1_on	0	3.88667	0	0	2	1
1x38	7x39	cb1_on	0	4.71	0	0	2	1
2x57	2x61	cb1_on	0	10.36	1	1	1	1
2x60	Lig	cb1_on	0	4.44	1	0	1	0
2x61	Lig	cb1_on	0	3.46	0	1	1	0
2x64	Lig	cb1_on	0	11	0	1	1	0
2x65	Lig	cb1_on	0	7.55	0	1	1	0
3x29	Lig	cb1_on	0	3.63667	0	0	1	0
3x32	3x36	cb1_on	0	3.49333	0	1	1	1
3x33	Lig	cb1_on	0	9.01667	0	1	1	0
3x36	7x41	cb1_on	0	8.84667	1	1	1	1
3x36	Lig	cb1_on	0	4.75	1	1	1	0
E2.F268	E2.I271	cb1_on	0	5.44	1	1	1	2
7x34	E2.F268	cb1_on	0	2.85667	0	1	1	1
5x39	Lig	cb1_on	0	4.61667	0	0	1	0
5x43	6x48	cb1_on	0	3.43667	1	1	1	2
5x43	6x55	cb1_on	0	3.87667	1	1	1	2
5x43	Lig	cb1_on	0	6.30333	1	1	1	0
5x44	6x52	cb1_on	0	2.85333	0	0	2	2
5x44	6x55	cb1_on	0	5.83333	0	0	2	2
6x55	7x34	cb1_on	0	3.32	1	0	2	1
7x34	Lig	cb1_on	0	3.74	0	1	1	0
2x65	NT.L111	cb1_on	0	3	0	1	1	2
2x57	3x32	cb1_on	0	4.37	1	1	1	1
2x61	7x38	cb1_on	0	4.40667	0	1	1	1
2x64	E1.H181	cb1_on	0	3.39333	0	1	1	2
3x25	3x29	cb1_on	0	3.65333	1	2	2	1
6x48	6x51	cb1_on	0	4.17333	1	0	2	1
6x48	6x52	cb1_on	0	4.55333	1	0	2	2
2x64	E1.R182	cb1_on	0	4.63333	0	1	1	2
5x39	5x42	cb1_on	0	2.40667	0	0	1	2
1x39	2x62	cb1_on	0	2.06667	1	0	1	2
1x39	7x39	cb1_on	0	2.04667	1	0	1	1
3x40	6x48	cb1_on	0	2.04333	0	0	2	2
2x58	2x62	cb1_on	0	1.53667	0	0	2	2
1x39	1x40	cb1_on	0	1.5	1	0	1	2
1x36	2x62	cb1_on	0	1.08333	0	0	2	2
6x51	7x40	cb1_on	0	0.923333	1	0	1	2
NT.D104	NT.E106	cb1_on	0	0.866667	0	0	2	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	cb1_off	5TGZ-CB₁-AM6538 5U09-CB₁-Taranabant
	cb1_on	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2

Network Difference
Value	cb1_off	cb1_on
I_min	3.4	2.70667
Number of Linked Nodes	285	282
Number of Specific Nodes	12 (4.21%)	9 (3.19%)
Number of Shared Nodes	273 (95.79%)	273 (96.81%)
Number of Links	318	320
Number of Specific Links	168 (52.83%)	170 (53.13%)
Number of Shared Links	150 (47.17%)	150 (46.88%)
Number of Hubs	46	41
Number of Specific Hubs	26 (56.52%)	21 (51.22%)
Number of Shared Hubs	20 (43.48%)	20 (48.78%)
Average % Shared Neighbours (Jaccard)	35.23
Average % Shared Neighbours (Otsuka)	43.98
Average % Shared Neighbours (Overlap Coefficient)	52.02
Average % Shared Cliques (k3-6)	76.67
Graphlets Similarity	0.650852

Paths Difference
Value	cb1_off	cb1_on
Number Of Nodes in MetaPath	58	58
Specific Nodes in MetaPath	31 (53.45%)	31 (53.45%)
Shared Nodes in MetaPath	273 (95.79%)	273 (95.79%)
Number Of Links MetaPath	60	61
Specific Links in MetaPath	49 (81.67%)	50 (81.97%)
Shared Links in MetaPath	150 (47.17%)	150 (47.17%)
Number of Shortest Paths	62483	48236
Length Of Smallest Path	3	3
Average Path Length	14.0211	13.2571
Length of Longest Path	31	30
Minimum Path Strength	0.7525	0.895
Average Path Strength	6.63909	4.60333
Maximum Path Strength	23.9225	12.7583
Minimum Path Correlation	0.7	0.7
Average Path Correlation	0.918223	0.918247
Maximum Path Correlation	0.99	0.99
Minimum % Of Corr. Nodes	3.44828	3.57143
Average % Of Corr. Nodes	41.5775	44.883
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	48.0755	40.438
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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