Orange: nodes, hubs and links specific of ccr_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of ccr_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner ccr_on_gp Avg Int. Strength ccr_off Avg Int. Strength ccr_on_gp Num Of Links ccr_off Num Of Links ConSurf
1G.HN.11 ccr_on_gp00503
2G.HN.43 ccr_on_gp00408
3G.HN.45 ccr_on_gp00404
4G.S1.02 ccr_on_gp1000504
5G.S1.04 ccr_on_gp200407
6G.S1.06 ccr_on_gp400408
7G.S1.07 ccr_on_gp200409
8G.S2.01 ccr_on_gp300409
9G.S2.03 ccr_on_gp200408
10G.S2.08 ccr_on_gp83.33330505
11G.S3.03 ccr_on_gp800607
12G.S3.04 ccr_on_gp600406
13G.S3.06 ccr_on_gp1000606
14G.S3.07 ccr_on_gp400409
15G.s3h2.03 ccr_on_gp600509
16G.H2.03 ccr_on_gp33.33330409
17G.H2.04 ccr_on_gp16.66670409
18G.H2.06 ccr_on_gp1000709
19G.H2.07 ccr_on_gp1000709
20G.H2.09 ccr_on_gp500408
21G.h2s4.01 ccr_on_gp93.33330609
22G.S4.02 ccr_on_gp500407
23G.S4.03 ccr_on_gp400407
24G.S4.04 ccr_on_gp600609
25G.s4h3.02 ccr_on_gp300409
26G.s4h3.04 ccr_on_gp600708
27G.H3.01 ccr_on_gp00409
28G.H3.09 ccr_on_gp1000709
29G.H3.13 ccr_on_gp33.33330405
30G.H3.17 ccr_on_gp700604
31G.H3.18 ccr_on_gp700409
32G.S5.03 ccr_on_gp53.33330408
33G.S5.04 ccr_on_gp900509
34G.S5.05 ccr_on_gp86.66670609
35G.S5.07 ccr_on_gp400409
36G.HG.04 ccr_on_gp800508
37G.HG.13 ccr_on_gp300406
38G.HG.15 ccr_on_gp56.66670407
39G.hgh4.01 ccr_on_gp53.33330404
40G.hgh4.02 ccr_on_gp1000608
41G.H4.03 ccr_on_gp300403
42G.H4.10 ccr_on_gp300406
43G.H4.15 ccr_on_gp53.33330508
44G.h4s6.02 ccr_on_gp400407
45G.h4s6.12 ccr_on_gp6.666670404
46G.S6.02 ccr_on_gp93.33330608
47G.S6.05 ccr_on_gp200405
48G.s6h5.05 ccr_on_gp200509
49G.H5.03 ccr_on_gp500408
50G.H5.08 ccr_on_gp800608
51G.H5.20 ccr_on_gp400508
52G.H5.26 ccr_on_gp53.33330405
53b.1x4 ccr_on_gp00608
54b.h2x1 ccr_on_gp100505
55b.lhb1x3 ccr_on_gp400502
56b.lhb1x6 ccr_on_gp400403
57b.l1x3 ccr_on_gp1000709
58b.b2x1 ccr_on_gp800508
59b.b2x5 ccr_on_gp1000507
60b.b3x3 ccr_on_gp400408
61b.l3x2 ccr_on_gp46.66670509
62b.b4x2 ccr_on_gp200408
63b.b4x3 ccr_on_gp53.33330407
64b.b4x5 ccr_on_gp500407
65b.b4x6 ccr_on_gp1000709
66b.l4x2 ccr_on_gp63.33330404
67b.b5x2 ccr_on_gp00407
68b.b5x3 ccr_on_gp1000609
69b.b5x5 ccr_on_gp800405
70b.b5x7 ccr_on_gp600407
71b.l5x1 ccr_on_gp63.33330508
72b.l5x5 ccr_on_gp1000709
73b.b6x5 ccr_on_gp800706
74b.l6x5 ccr_on_gp33.33330404
75b.b7x1 ccr_on_gp1000504
76b.l7x2 ccr_on_gp1000609
77b.l7x4 ccr_on_gp300509
78b.b8x3 ccr_on_gp53.33330406
79b.b8x4 ccr_on_gp1000506
80b.l8x1 ccr_on_gp53.33330405
81b.l9x3 ccr_on_gp800509
82b.l9x6 ccr_on_gp10001008
83b.b10x5 ccr_on_gp800609
84b.l10x1 ccr_on_gp300403
85b.b11x4 ccr_on_gp700409
86b.b11x5 ccr_on_gp00406
87b.l11x2 ccr_on_gp700409
88b.b12x3 ccr_on_gp33.33330408
89b.b12x5 ccr_on_gp00406
90b.b12x6 ccr_on_gp1000708
91b.b13x7 ccr_on_gp93.33330507
92b.l13x3 ccr_on_gp1000609
93b.l13x6 ccr_on_gp900509
94b.b15x1 ccr_on_gp800609
95b.b15x2 ccr_on_gp33.33330406
96b.b15x3 ccr_on_gp900409
97b.l15x1 ccr_on_gp700507
98b.l15x2 ccr_on_gp600509
99b.b16x4 ccr_on_gp800406
100b.b16x5 ccr_on_gp36.66670505
101b.b16x6 ccr_on_gp1000608
102b.b17x5 ccr_on_gp500407
103b.b17x7 ccr_on_gp800408
104b.l17x3 ccr_on_gp1000709
105b.l17x6 ccr_on_gp800509
106b.b18x3 ccr_on_gp73.33330408
107b.l18x1 ccr_on_gp1000806
108b.l18x2 ccr_on_gp600407
109b.l18x3 ccr_on_gp200405
110b.b19x2 ccr_on_gp1000606
111b.b19x4 ccr_on_gp73.33330508
112b.l19x2 ccr_on_gp800509
113b.b20x4 ccr_on_gp1000508
114b.b20x6 ccr_on_gp1000606
115b.b20x7 ccr_on_gp100409
116b.l20x2 ccr_on_gp400509
117b.b21x1 ccr_on_gp400507
118b.b21x2 ccr_on_gp100406
119b.b21x4 ccr_on_gp200405
120b.b21x5 ccr_on_gp400404
121b.b21x7 ccr_on_gp900605
122b.l21x5 ccr_on_gp400404
123b.b22x5 ccr_on_gp93.33330407
124b.l22x5 ccr_on_gp93.33330709
125b.b23x6 ccr_on_gp1000707
126b.l23x1 ccr_on_gp200406
127b.b24x4 ccr_on_gp56.66670406
128b.b24x6 ccr_on_gp1000408
129b.l24x2 ccr_on_gp200406
130b.b25x3 ccr_on_gp73.33330505
131b.l25x3 ccr_on_gp1000509
132b.b26x3 ccr_on_gp200406
133b.b27x1 ccr_on_gp200406
134b.l27x1 ccr_on_gp1000709
135b.l27x2 ccr_on_gp93.33330409
136b.b28x3 ccr_on_gp33.33330407
137b.b28x4 ccr_on_gp900406
138b.b28x6 ccr_on_gp1000409
139b.b28x7 ccr_on_gp500409
140g.h1x1 ccr_on_gp00402
141g.l1x4 ccr_on_gp200508
142g.h2x11 ccr_on_gp73.33330406
143g.ctx3 ccr_on_gp800609
144g.ctx6 ccr_on_gp200406
145g.ctx14 ccr_on_gp53.33330609
146g.ctx15 ccr_on_gp53.33330409
147g.ctx16 ccr_on_gp800808
1481x57 ccr_on_gp400417
1491x59 ccr_on_gp00434
1502x37 ccr_on_gp00428
1512x46 ccr_on_gp400419
1522x50 ccr_on_gp36.66670429
1532x53 ccr_on_gp800436
1542x57 ccr_on_gp400518
1552x63 ccr_on_gp1050425
156E1x52 ccr_on_gp33.33330537
1573x32 ccr_on_gp70100737
1583x38 ccr_on_gp00427
1593x49 ccr_on_gp600438
1603x50 ccr_on_gp800439
161E2x52 ccr_on_gp00425
1625x47 ccr_on_gp200428
163I3 ccr_on_gp200504
1646x34 ccr_on_gp200416
1656x49 ccr_on_gp400426
1666x60 ccr_on_gp00435
1676x61 ccr_on_gp500424
1687x30 ccr_on_gp00414
1697x37 ccr_on_gp00436
1707x38 ccr_on_gp26.66670436
1717x45 ccr_on_gp8050539
1727x49 ccr_on_gp600629
1738x50 ccr_on_gp8050538
1748x53 ccr_on_gp200435
175I2x57 ccr_on_gp500530
176g.ntx4 ccr_on_gp00400
177Lig Shared10010023240
178NT Shared8050543
1791x39 Shared8050558
1802x38 Shared600546
1812x42 Shared100100647
1822x60 Shared46.6667100446
183E1x50 Shared100100678
1843x36 Shared43.333350447
1853x37 Shared70100647
1863x41 Shared6.666670445
1873x42 Shared80100647
1883x51 Shared2050458
1894x50 Shared5050459
190E2 Shared10010014144
1915x35 Shared2050542
1925x50 Shared400459
1935x58 Shared1000759
1946x40 Shared050447
1956x44 Shared60100559
1966x47 Shared63.33330547
1976x48 Shared100100559
1986x51 Shared73.3333100447
199E3 Shared4050644
2007x42 Shared10050547
2017x53 Shared10050659
2021x35 ccr_off2050355
2031x60 ccr_off200155
2043x28 ccr_off200345
2053x33 ccr_off6050345
2064x64 ccr_off050344
2076x45 ccr_off050346
   
Orange: nodes, hubs and links specific of ccr_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of ccr_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner ccr_on_gp Recurrence ccr_off Recurrence ccr_on_gp Hub1? ccr_off Hub1? ccr_on_gp Hub2? ccr_off Hub2? ConSurf1 ConSurf2
1b.b3x2 b.b4x6 ccr_on_gp10.00870NoNoYesNo59
2b.b2x5 b.b3x2 ccr_on_gp10.25190YesNoNoNo75
3b.b2x3 b.b2x5 ccr_on_gp18.54910NoNoYesNo67
4b.b26x2 b.b2x3 ccr_on_gp18.92140NoNoNoNo76
5b.b26x1 b.b26x2 ccr_on_gp19.31720NoNoNoNo97
6b.b26x1 b.l27x1 ccr_on_gp19.51990NoNoYesNo99
7b.b2x1 b.l27x1 ccr_on_gp12.46820YesNoYesNo89
8b.b2x1 b.l3x1 ccr_on_gp12.90160YesNoNoNo89
9b.l3x1 b.l5x5 ccr_on_gp13.31210NoNoYesNo99
10G.H3.17 b.l27x1 ccr_on_gp15.36040YesNoYesNo49
11G.H3.15 G.H3.17 ccr_on_gp58.31210NoNoYesNo84
12G.H3.15 G.H3.18 ccr_on_gp58.45810NoNoYesNo89
13G.H3.18 G.S4.02 ccr_on_gp49.88280YesNoYesNo97
14G.S1.07 G.S4.02 ccr_on_gp50.00910YesNoYesNo97
15G.S1.07 G.S4.04 ccr_on_gp54.73510YesNoYesNo99
16G.S4.04 G.S5.04 ccr_on_gp96.12030YesNoYesNo99
17G.S5.04 G.S5.06 ccr_on_gp95.74380YesNoNoNo98
18G.S5.06 G.S6.05 ccr_on_gp91.05670NoNoYesNo85
19G.HG.01 G.S6.05 ccr_on_gp91.42860NoNoYesNo55
20G.HG.01 G.s6h5.02 ccr_on_gp1000NoNoNoNo57
21G.s6h5.02 G.s6h5.05 ccr_on_gp99.96920NoNoYesNo79
22G.H1.07 G.s6h5.05 ccr_on_gp99.85470NoNoYesNo09
23G.H1.07 G.H5.03 ccr_on_gp99.83640NoNoYesNo08
24G.H5.03 G.S5.05 ccr_on_gp98.69260YesNoYesNo89
25G.HG.04 G.s4h3.04 ccr_on_gp10.21990YesNoYesNo88
26b.l5x5 b.l7x2 ccr_on_gp12.37550YesNoYesNo99
27b.b2x4 b.b6x5 ccr_on_gp16.8510NoNoYesNo66
28b.b10x4 b.b2x4 ccr_on_gp16.96260NoNoNoNo66
29b.b10x2 b.b10x4 ccr_on_gp15.44550NoNoNoNo66
30b.b10x2 b.b14x3 ccr_on_gp15.62720NoNoNoNo65
31b.b11x5 b.b14x3 ccr_on_gp17.00240YesNoNoNo65
32b.b10x1 b.b11x5 ccr_on_gp27.53580NoNoYesNo96
33b.b10x1 b.l9x6 ccr_on_gp27.75010NoNoYesNo98
34G.S5.03 G.S5.05 ccr_on_gp93.24740YesNoYesNo89
35G.H5.10 G.S5.03 ccr_on_gp98.21930NoNoYesNo78
36G.H5.10 G.S6.02 ccr_on_gp98.18120NoNoYesNo78
37G.S6.02 I3 ccr_on_gp96.50740YesNoYesNo84
386x29 I3 ccr_on_gp97.38990NoNoYesNo54
396x29 G.H5.26 ccr_on_gp97.3050NoNoYesNo55
40G.H5.20 G.H5.26 ccr_on_gp97.02610YesNoYesNo85
41G.H5.20 G.H5.25 ccr_on_gp84.1290YesNoNoNo86
423x50 G.H5.25 ccr_on_gp72.12390YesNoNoNo96
433x50 5x58 ccr_on_gp12.80740YesNoYesYes99
446x37 G.H5.25 ccr_on_gp12.3260NoNoNoNo76
455x58 6x37 ccr_on_gp12.4221.48414YesYesNoNo97
463x54 G.H5.20 ccr_on_gp12.3550NoNoYesNo88
473x54 5x61 ccr_on_gp12.19470NoNoNoNo88
48G.H2.07 b.l9x6 ccr_on_gp56.69710YesNoYesNo98
49G.H2.06 b.l9x6 ccr_on_gp33.05890YesNoYesNo98
50G.H2.04 G.H3.08 ccr_on_gp50.61680YesNoNoNo99
51G.H2.06 b.l17x6 ccr_on_gp31.42270YesNoYesNo99
52G.H4.03 G.HG.01 ccr_on_gp10.12970YesNoNoNo35
532x42 3x46 ccr_on_gp31.01830YesYesNoNo79
543x46 7x53 ccr_on_gp31.19740NoNoYesYes99
553x50 7x53 ccr_on_gp61.07670YesNoYesYes99
562x42 3x49 ccr_on_gp19.07880YesYesYesNo78
572x37 I2x57 ccr_on_gp17.67550YesNoYesNo80
58b.h2x1 b.h2x5 ccr_on_gp14.50720YesNoNoNo55
59b.b21x4 g.h2x1 ccr_on_gp13.18850YesNoNoNo58
60b.b21x2 g.h2x1 ccr_on_gp12.86090YesNoNoNo68
61b.1x2 b.b21x2 ccr_on_gp11.89140NoNoYesNo16
62b.1x2 b.1x3 ccr_on_gp11.58080NoNoNoNo11
63b.1x3 b.1x4 ccr_on_gp10.93930NoNoYesNo18
64b.l17x5 b.l17x6 ccr_on_gp32.26490NoNoYesNo69
65b.l17x5 b.l19x2 ccr_on_gp32.02030NoNoYesNo69
66b.l17x3 b.l19x2 ccr_on_gp29.65710YesNoYesNo99
67b.b20x6 b.l17x3 ccr_on_gp14.6720YesNoYesNo69
68b.b21x5 b.h2x1 ccr_on_gp12.84180YesNoYesNo45
69b.b3x3 b.b6x5 ccr_on_gp11.13120YesNoYesNo86
70b.l11x1 b.l9x6 ccr_on_gp19.98880NoNoYesNo98
71b.b11x6 b.l11x1 ccr_on_gp21.02310NoNoNoNo99
72b.b11x6 b.l9x3 ccr_on_gp19.15090NoNoYesNo99
73b.b12x6 b.l9x3 ccr_on_gp17.33280YesNoYesNo89
74b.b11x2 b.b12x6 ccr_on_gp15.21720NoNoYesNo78
75b.b19x4 b.l17x3 ccr_on_gp12.9370YesNoYesNo89
76b.b15x2 b.b19x2 ccr_on_gp11.49040YesNoYesNo66
77b.l25x6 b.l27x1 ccr_on_gp10.37270NoNoYesNo89
78b.l23x1 b.l25x6 ccr_on_gp52.32160YesNoNoNo68
79b.l21x7 b.l23x1 ccr_on_gp40.28720NoNoYesNo56
80b.b23x6 b.l21x7 ccr_on_gp38.65710YesNoNoNo75
81b.b23x6 b.b24x6 ccr_on_gp35.07880YesNoYesNo78
82b.b21x7 b.b24x6 ccr_on_gp35.02880YesNoYesNo58
83b.b21x7 b.b23x2 ccr_on_gp12.12810YesNoNoNo56
84b.b21x5 b.b21x7 ccr_on_gp14.37030YesNoYesNo45
85b.b22x5 b.b23x2 ccr_on_gp10.89070YesNoNoNo76
86b.b20x5 b.b21x4 ccr_on_gp11.63020NoNoYesNo75
87b.b22x1 b.l23x1 ccr_on_gp12.51820NoNoYesNo86
88b.b22x1 b.b22x2 ccr_on_gp12.24340NoNoNoNo88
897x49 7x53 ccr_on_gp37.63030YesNoYesYes99
902x50 7x46 ccr_on_gp27.6870YesNoNoNo98
911x57 2x40 ccr_on_gp10.21860YesNoNoNo78
925x54 6x44 ccr_on_gp24.85310NoNoYesYes79
93G.H2.04 G.H2.07 ccr_on_gp50.24130YesNoYesNo99
94G.H3.08 G.S4.04 ccr_on_gp50.74310NoNoYesNo99
95b.l7x2 b.l9x6 ccr_on_gp12.00370YesNoYesNo98
96b.b22x2 b.b26x3 ccr_on_gp11.98960NoNoYesNo86
97b.b20x5 b.b21x7 ccr_on_gp11.83940NoNoYesNo75
98G.H3.17 b.l25x6 ccr_on_gp42.16730YesNoNoNo48
995x58 5x61 Shared12.153918.4289YesYesNoNo98
1002x38 2x42 Shared10.471159.2272YesYesYesYes67
1012x50 7x49 Shared27.835715.9263YesNoYesNo99
1022x53 7x46 Shared27.5112.738YesNoNoNo68
1032x53 3x32 Shared22.296212.1955YesNoYesNo67
1043x32 Lig Shared16.629451.1566YesNoYesYes70
1052x37 2x40 Shared23.979826.868YesNoNoNo88
1062x40 I1x48 Shared13.247323.7001NoNoNoNo86
1076x44 6x48 Shared13.160340.7062YesYesYesYes99
1085x54 5x58 Shared24.774526.4841NoNoYesYes79
1091x35 Lig ccr_off017.5691NoYesYesYes50
1102x54 7x46 ccr_off010.6397NoNoNoNo68
1117x38 Lig ccr_off1.638847.5947YesNoYesYes60
1126x51 7x38 ccr_off2.6281748.1679YesYesYesNo76
1136x48 6x51 ccr_off056.2487YesYesYesYes97
1146x48 7x45 ccr_off4.6462112.3286YesYesYesNo99
1156x47 7x45 ccr_off1.3933819.2477YesYesYesNo79
1166x44 6x45 ccr_off071.0594YesYesNoYes96
1176x41 6x45 ccr_off061.1105NoNoNoYes86
1183x43 6x41 ccr_off038.2037NoNoNoNo88
1193x43 6x40 ccr_off035.7677NoNoYesYes87
1206x40 7x49 ccr_off017.3132YesYesYesNo79
1211x50 2x50 ccr_off0.55817414.5292NoNoYesNo99
1223x32 3x33 ccr_off1.6328256.868YesNoNoYes75
1233x33 3x37 ccr_off074.8874NoYesYesYes57
1243x37 5x46 ccr_off0.664648100YesYesNoNo73
1253x41 5x46 ccr_off0.50194798.0246YesYesNoNo53
1263x41 4x49 ccr_off3.1759289.6469YesYesNoNo56
1273x42 4x49 ccr_off2.2600432.7482YesYesNoNo76
1283x42 4x50 ccr_off0.80854928.0092YesYesYesYes79
1292x48 4x50 ccr_off018.5722NoNoYesYes69
1302x44 2x48 ccr_off0.64106316.9345NoNoNoNo66
1313x45 4x49 ccr_off1.9777165.2047NoNoNoNo66
1322x42 3x45 ccr_off2.1205863.9406YesYesNoNo76
1332x38 3x49 ccr_off0.0011963354.0839YesYesYesNo68
1342x39 3x49 ccr_off9.0213745.6192NoNoYesNo88
1352x37 2x39 ccr_off8.8167928.4289YesNoNoNo88
1368x53 I1x48 ccr_off6.8879622.4053YesNoNoNo56
1371x56 8x53 ccr_off010.2354NoNoYesNo75
1381x60 8x53 ccr_off0.64106311.2692NoYesYesNo55
1396x40 7x53 ccr_off2.062310.5578YesYesYesYes79
1402x60 Lig ccr_off0.076394319.1914YesYesYesYes60
1412x60 E1x50 ccr_off011.3715YesYesYesYes68
142E1x50 E1x52 ccr_off5.0825313.1013YesYesYesNo87
143E2 Lig ccr_off6.1105235.911YesYesYesYes40
144E1x50 E2 ccr_off3.5536215.3019YesYesYesYes84
1453x33 4x61 ccr_off0.23413918.8639NoYesNoNo54
1463x36 3x37 ccr_off3.2945358.4852YesYesYesYes77
1473x36 6x48 ccr_off7.6438814.4831YesYesYesYes79
1483x36 5x43 ccr_off3.8045117.4872YesYesNoNo75
1493x40 6x44 ccr_off010.9058NoNoYesYes79
1505x50 6x45 ccr_off011.8936YesYesNoYes96
1513x44 5x50 ccr_off1.6123113.2753NoNoYesYes79
1525x54 6x41 ccr_off027.7892NoNoNoNo78
1532x39 3x50 ccr_off017.6049NoNoYesNo89
1543x51 5x61 ccr_off011.7042YesYesNoNo88
1555x43 6x52 ccr_off015.3634NoNoNoNo58
156E3 Lig ccr_off1.1245514.1607YesYesYesYes40
1575x39 E2 ccr_off0.22781616.0952NoNoYesYes54
1584x61 5x39 ccr_off017.8813NoNoNoNo45
1593x36 6x44 ccr_off043.2753YesYesYesYes79

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
1x31Ligccr_off5.4600010
1x351x39Shared12.8959.159331012
1x357x39ccr_off5.1601012
1x35Ligccr_off6.95501010
1x392x57Shared5.414.9331222
1x397x39Shared8.743.010671222
1x397x42Shared13.175.538331221
2x533x32Shared9.810.59030221
2x537x42Shared4.987.778330221
2x562x60Shared8.493.1540221
2x60E1x50ccr_off5.62501212
2x607x42ccr_off4.6501211
2x60LigShared22.08513.29271210
2x63E1x50Shared7.9157.409671212
E1x49E2Shared13.194.689671021
E1x50E2Shared4.8055.2791221
3x223x26Shared6.025.0761222
3x22E2Shared14.1155.341221
3x26E2ccr_off5.3401021
3x294x65Shared12.5610.66371211
3x29LigShared7.9254.4831210
3x323x33Shared8.485.872671212
3x32LigShared10.8456.495331210
4x64E2Shared14.84512.70071221
4x645x32ccr_off4.33501221
4x645x35Shared14.536.246671222
4x65Ligccr_off3.9401010
E2E2Shared60.93554.43671211
E2E2x52Shared4.753.390671211
5x35E2Shared6.067.3971221
5x36E2Shared5.5154.3321211
5x39E2Shared4.025.8131021
5x335x37ccr_off10.1600212
5x406x55Shared4.492.8371012
5x406x59Shared14.137.1861012
6x516x55Shared10.098.8970022
6x517x37Shared5.6156.0460022
6x517x38Shared7.8558.3740021
6x547x34Shared3.93.5750021
6x547x37Shared5.5556.640670022
6x587x30Shared4.8052.523330022
6x587x34ccr_off500021
6x617x27Shared4.973.083331211
7x35LigShared14.5453.777671210
7x38LigShared12.484.9331210
7x42Ligccr_off4.23501210
E2x52LigShared8.3853.9981210
E2LigShared39.8652.28371210
5x40Ligccr_off3.9401010
E2x51LigShared9.0256.256670210
1x24Ligccr_off4.42501010
7x31LigShared5.615.521330010
7x34LigShared3.945.594331210
LigNTShared19.4949.18931201
6x61LigShared5.644.1061210
5x32LigShared11.8857.1951210
1x241x27ccr_off9.86501012
2x63E2Shared5.762.877331211
5x31E2ccr_off4.4700021
5x325x36ccr_off4.1801211
6x62E3ccr_off6.57500021
7x357x38ccr_off5.73501211
7x24NTShared3.644.489330211
E3LigShared3.5855.471331210
1x352x64Shared3.153.832331012
7x28NTccr_off2.3600021
1x28LigShared2.1156.8170210
1x341x35ccr_off2.07500021
7x26E3Shared1.55.355330221
7x36Ligccr_off1.3500010
6x65E3ccr_off0.8500021
1x25NTccr_off0.68500021
7x24Ligccr_on_gp02.415330210
NTNTccr_on_gp011.11831211
1x357x35ccr_on_gp04.988671011
2x603x32ccr_on_gp03.6631211
3x327x42ccr_on_gp02.8031211
4x65E2x52ccr_on_gp03.486671011
E2E2x51ccr_on_gp07.157671211
E2x51E2x52ccr_on_gp03.605330211
5x32E2ccr_on_gp03.769671211
6x61E3ccr_on_gp02.991331211
6x64E3ccr_on_gp02.824670021
7x387x42ccr_on_gp05.011671211
1x247x28ccr_on_gp03.0241012
2x563x32ccr_on_gp02.4270221
2x577x42ccr_on_gp07.209330221
2x602x63ccr_on_gp03.3251211
2x63Ligccr_on_gp06.530671210
5x315x35ccr_on_gp03.1250022
7x27Ligccr_on_gp03.640210
1x277x28ccr_on_gp02.8650222
3x327x38ccr_on_gp03.891211
5x36Ligccr_on_gp02.6261210
E3E3ccr_on_gp03.0521211
5x325x35ccr_on_gp02.836671212
5x336x62ccr_on_gp02.2330212
5x33Ligccr_on_gp02.178670210
1x27NTccr_on_gp02.0460221
6x617x30ccr_on_gp02.033331212
1x317x35ccr_on_gp01.8960011
1x251x28ccr_on_gp01.4840021
6x657x30ccr_on_gp01.4620022
2x67Ligccr_on_gp01.4340010
7x367x37ccr_on_gp00.6890012

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
ccr_on_gp ccr6_on_gp
ccr8_on_gp
ccr2_on_gp
ccr1_on_gp
ccr5_on_gp
ccr_off ccr2_off
ccr5_off
Network Difference
Value ccr_on_gp ccr_off
Imin 2.397 3.89
Number of Linked Nodes 937 273
Number of Specific Nodes 664 (70.86%) 0  (0.00%)
Number of Shared Nodes 273 (29.14%) 273  (100.00%)
Number of Links 1182 300
Number of Specific Links 1004 (84.94%) 122  (40.67%)
Number of Shared Links 178 (15.06%) 178  (59.33%)
Number of Hubs 201 31
Number of Specific Hubs 176 (87.56%) 6  (19.35%)
Number of Shared Hubs 25 (12.44%) 25  (80.65%)
Average % Shared Neighbours (Jaccard) 12.23
Average % Shared Neighbours (Otsuka) 15.23
Average % Shared Neighbours (Overlap Coefficient) 18.33
Average % Shared Cliques (k3-6) 51.23
Graphlets Similarity 0.616118
Paths Difference
Value ccr_on_gp ccr_off
Number Of Nodes in MetaPath 108 58
Specific Nodes in MetaPath 89 (82.41%) 39  (67.24%)
Shared Nodes in MetaPath 273 (29.14%) 273  (29.14%)
Number Of Links MetaPath 108 61
Specific Links in MetaPath 98 (90.74%) 51  (83.61%)
Shared Links in MetaPath 178 (15.06%) 178  (15.06%)
Number of Shortest Paths 1152905 47722
Length Of Smallest Path 3 3
Average Path Length 27.4809 12.3819
Length of Longest Path 63 31
Minimum Path Strength 0.132 0.77
Average Path Strength 5.23882 7.15325
Maximum Path Strength 38.0579 27.3525
Minimum Path Correlation 0.702333 0.7
Average Path Correlation 0.972766 0.916277
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 1.96078 3.57143
Average % Of Corr. Nodes 46.076 47.8683
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 58.1937 43.2585
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download ccr_off_on_gp.zip<



You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.



You can also  read or  download a guide explaining the meaning of all files and numerical data.