Orange: nodes, hubs and links specific of class-a_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of class-a_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner class-a_on_gp Avg Int. Strength class-a_off Avg Int. Strength class-a_on_gp Num Of Links class-a_off Num Of Links ConSurf
11x59 class-a_on_gp04.7619425
22x46 class-a_on_gp34.77150419
32x53 class-a_on_gp18.928623.2143437
43x30 class-a_on_gp3.571430436
55x62 class-a_on_gp7.142860425
66x32 class-a_on_gp00417
76x49 class-a_on_gp00426
86x51 class-a_on_gp50.319932.7551536
96x59 class-a_on_gp3.571430434
107x38 class-a_on_gp19.591117.5238425
117x52 class-a_on_gp7.142860428
12G.HN.33 class-a_on_gp00404
13G.hns1.03 class-a_on_gp00404
14G.S1.06 class-a_on_gp12.69910409
15G.s1h1.04 class-a_on_gp00409
16G.H1.01 class-a_on_gp11.90480509
17G.S2.03 class-a_on_gp2.018630509
18G.S2.04 class-a_on_gp00407
19G.S2.06 class-a_on_gp12.50508
20G.S2.08 class-a_on_gp49.97940505
21G.S3.03 class-a_on_gp75.1420507
22G.S3.04 class-a_on_gp64.45830407
23G.S3.06 class-a_on_gp76.29830506
24G.S3.07 class-a_on_gp00509
25G.H2.03 class-a_on_gp00409
26G.H2.06 class-a_on_gp92.15680709
27G.H2.07 class-a_on_gp85.67630609
28G.h2s4.01 class-a_on_gp87.08180509
29G.S4.04 class-a_on_gp40.19450409
30G.s4h3.04 class-a_on_gp64.86020608
31G.H3.01 class-a_on_gp8.996070509
32G.H3.09 class-a_on_gp84.44740709
33G.H3.13 class-a_on_gp38.22980605
34G.H3.14 class-a_on_gp3.571430408
35G.H3.17 class-a_on_gp88.56080604
36G.H3.18 class-a_on_gp59.50780409
37G.S5.04 class-a_on_gp34.87390409
38G.S5.05 class-a_on_gp78.03940809
39G.S5.07 class-a_on_gp5.102370409
40G.s5hg.01 class-a_on_gp8.281570409
41G.HG.04 class-a_on_gp21.1310409
42G.HG.13 class-a_on_gp00406
43G.HG.14 class-a_on_gp00405
44G.hgh4.02 class-a_on_gp55.85830609
45G.hgh4.05 class-a_on_gp54.32990407
46G.hgh4.08 class-a_on_gp00403
47G.H4.05 class-a_on_gp14.28570504
48G.H4.10 class-a_on_gp24.30240407
49G.H4.13 class-a_on_gp00403
50G.H4.15 class-a_on_gp56.29620408
51G.H4.16 class-a_on_gp00503
52G.h4s6.02 class-a_on_gp23.05130407
53G.S6.02 class-a_on_gp83.08340708
54G.S6.05 class-a_on_gp25.78360505
55G.H5.03 class-a_on_gp19.33760508
56G.H5.08 class-a_on_gp86.55030408
57G.H5.17 class-a_on_gp20.07280506
58G.H5.20 class-a_on_gp2.380950408
59G.H5.26 class-a_on_gp250605
60b.1x1 class-a_on_gp00404
61b.1x3 class-a_on_gp00401
62b.1x11 class-a_on_gp00508
63b.lh12x2 class-a_on_gp00408
64b.h2x1 class-a_on_gp7.142860505
65b.lhb1x3 class-a_on_gp15.23810502
66b.lhb1x11 class-a_on_gp4.037270404
67b.b1x4 class-a_on_gp9.523810407
68b.b1x6 class-a_on_gp22.03970409
69b.l1x3 class-a_on_gp99.7930609
70b.b2x1 class-a_on_gp74.57910508
71b.b2x5 class-a_on_gp98.78690607
72b.b3x3 class-a_on_gp25.22870508
73b.l3x2 class-a_on_gp51.47390509
74b.b4x2 class-a_on_gp7.857140408
75b.b4x3 class-a_on_gp46.10490407
76b.b4x5 class-a_on_gp38.82250407
77b.b4x6 class-a_on_gp1000709
78b.l4x2 class-a_on_gp2.857140404
79b.b5x2 class-a_on_gp7.936510407
80b.b5x3 class-a_on_gp95.18460609
81b.b5x5 class-a_on_gp33.28930405
82b.b5x7 class-a_on_gp65.76650407
83b.l5x1 class-a_on_gp67.93570508
84b.l5x5 class-a_on_gp99.00360709
85b.b6x5 class-a_on_gp83.6810706
86b.l6x5 class-a_on_gp42.62410404
87b.b7x1 class-a_on_gp67.69580504
88b.b7x4 class-a_on_gp7.142860408
89b.l7x4 class-a_on_gp14.28570409
90b.b8x3 class-a_on_gp18.43580406
91b.b8x4 class-a_on_gp97.04850506
92b.l8x1 class-a_on_gp3.690480405
93b.l8x3 class-a_on_gp00403
94b.b9x3 class-a_on_gp8.669770406
95b.l9x3 class-a_on_gp90.00020509
96b.l9x6 class-a_on_gp98.22980808
97b.b10x5 class-a_on_gp42.08660609
98b.b11x4 class-a_on_gp43.37470509
99b.l11x2 class-a_on_gp82.5560409
100b.b12x6 class-a_on_gp99.21950708
101b.b12x7 class-a_on_gp7.142860409
102b.b13x7 class-a_on_gp95.72250507
103b.l13x3 class-a_on_gp99.90080609
104b.l13x6 class-a_on_gp46.64860409
105b.l13x7 class-a_on_gp46.78550409
106b.b14x3 class-a_on_gp48.50360405
107b.b15x1 class-a_on_gp69.90490509
108b.b15x2 class-a_on_gp24.53170406
109b.b15x3 class-a_on_gp31.02480409
110b.l15x1 class-a_on_gp35.00820407
111b.l15x2 class-a_on_gp62.1640509
112b.b16x4 class-a_on_gp94.19550406
113b.b16x5 class-a_on_gp31.68520405
114b.b16x6 class-a_on_gp1000608
115b.b17x7 class-a_on_gp81.34820408
116b.l17x3 class-a_on_gp99.57820609
117b.l17x6 class-a_on_gp70.20370509
118b.b18x3 class-a_on_gp75.96410408
119b.b18x5 class-a_on_gp17.85710405
120b.l18x1 class-a_on_gp89.1540806
121b.l18x2 class-a_on_gp25.41420407
122b.l18x3 class-a_on_gp7.142860405
123b.b19x2 class-a_on_gp95.53560606
124b.b19x4 class-a_on_gp71.83460408
125b.l19x2 class-a_on_gp77.79250509
126b.b20x4 class-a_on_gp92.56730508
127b.b20x6 class-a_on_gp98.71970506
128b.l20x2 class-a_on_gp18.42820609
129b.b21x1 class-a_on_gp68.78380607
130b.b21x2 class-a_on_gp9.523810506
131b.b21x5 class-a_on_gp7.142860404
132b.b21x7 class-a_on_gp94.51910605
133b.l21x2 class-a_on_gp00404
134b.b22x5 class-a_on_gp51.81770507
135b.l22x5 class-a_on_gp80.99350609
136b.b23x6 class-a_on_gp99.06830607
137b.l23x1 class-a_on_gp27.12450406
138b.b24x4 class-a_on_gp54.61450406
139b.b24x6 class-a_on_gp54.54910408
140b.l24x2 class-a_on_gp14.28570506
141b.l24x3 class-a_on_gp14.28570405
142b.l25x3 class-a_on_gp99.04840509
143b.l25x6 class-a_on_gp37.47020408
144b.l26x1 class-a_on_gp00407
145b.l26x5 class-a_on_gp00405
146b.l27x1 class-a_on_gp1000709
147b.l27x2 class-a_on_gp78.92210409
148b.b28x2 class-a_on_gp00404
149b.b28x3 class-a_on_gp21.19450507
150b.b28x4 class-a_on_gp85.21640406
151b.b28x6 class-a_on_gp98.69760509
152g.h2x5 class-a_on_gp00405
153g.h2x11 class-a_on_gp41.53060409
154g.ctx3 class-a_on_gp56.74680404
155g.ctx6 class-a_on_gp7.142860405
156G.HN.11 class-a_on_gp00600
157g.h1x1 class-a_on_gp00600
158g.ctx16 class-a_on_gp59.34780600
159E1 class-a_on_gp00510
160G.HN.29 class-a_on_gp00400
161G.hgh4.13 class-a_on_gp00400
162H.HA.16 class-a_on_gp00400
163H.HA.26 class-a_on_gp00400
164H.hahb.06 class-a_on_gp00400
165H.HB.02 class-a_on_gp00400
166H.HB.10 class-a_on_gp00400
167H.HD.07 class-a_on_gp00500
168H.HE.02 class-a_on_gp00400
169H.HE.05 class-a_on_gp00400
170H.hehf.04 class-a_on_gp00400
171H.HF.03 class-a_on_gp00400
172NT Shared33.788838.571412125
1731x39 Shared30.441434.3864457
1741x60 Shared09.52381665
1752x40 Shared00448
1762x41 Shared04.7619445
1772x42 Shared52.514226.8844547
1782x50 Shared65.780619.1429559
179E1x50 Shared65.189863.4722458
180E1x52 Shared20.852414.2857447
1813x50 Shared63.237743.5684579
182E2 Shared98.563210022224
1835x47 Shared26.4220448
1845x58 Shared78.088817.8571649
1856x44 Shared46.610534.381449
1866x48 Shared88.291986.4845558
187E3 Shared59.592823.2143882
1887x34 Shared11.904814.2857444
1897x42 Shared49.257841.0714547
1907x49 Shared42.94351.78571559
1917x53 Shared74.47644.9901649
1928x50 Shared36.091324.0952558
1938x54 Shared00446
194Lig Shared99.79310019150
1951x32 class-a_off00345
1961x50 class-a_off19.18650349
1972x44 class-a_off014.2857355
1982x57 class-a_off25.26126.47619247
1993x51 class-a_off30.526414.2857357
2003x56 class-a_off7.142860246
201I3 class-a_off14.28579.52381244
2026x31 class-a_off04.7619144
2037x45 class-a_off027.4048349
2047x56 class-a_off00147
205CT class-a_off014.2857175
   
Orange: nodes, hubs and links specific of class-a_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of class-a_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner class-a_on_gp Recurrence class-a_off Recurrence class-a_on_gp Hub1? class-a_off Hub1? class-a_on_gp Hub2? class-a_off Hub2? ConSurf1 ConSurf2
12x42 3x49 class-a_on_gp10.30820YesYesNoNo78
27x49 7x53 class-a_on_gp32.22220YesYesYesYes99
33x36 6x48 class-a_on_gp42.80651.31781NoNoYesYes78
43x36 Lig class-a_on_gp42.49250NoNoYesYes70
53x50 5x58 class-a_on_gp28.69010YesYesYesYes99
65x54 5x58 class-a_on_gp25.8120NoNoYesYes89
75x54 6x44 class-a_on_gp25.63650NoNoYesYes89
83x50 7x53 class-a_on_gp35.64520YesYesYesYes99
93x50 G.H5.25 class-a_on_gp78.4050YesYesNoNo97
10G.H5.20 G.H5.25 class-a_on_gp78.5790YesNoNoNo87
11G.S6.02 G.h4s6.12 class-a_on_gp42.95430YesNoNoNo84
12G.H5.17 G.h4s6.12 class-a_on_gp42.72810YesNoNoNo64
13G.H5.17 G.H5.26 class-a_on_gp84.71490YesNoYesNo65
14G.H5.20 G.H5.26 class-a_on_gp82.7220YesNoYesNo85
15G.H5.13 G.S6.02 class-a_on_gp43.0740NoNoYesNo78
16G.H5.13 G.H5.17 class-a_on_gp42.73360NoNoYesNo76
17b.b3x2 b.b4x6 class-a_on_gp17.48280NoNoYesNo59
18b.b2x5 b.b3x2 class-a_on_gp17.71180YesNoNoNo75
19b.b2x3 b.b2x5 class-a_on_gp45.16610NoNoYesNo67
20b.b26x2 b.b2x3 class-a_on_gp45.3930NoNoNoNo76
21b.b26x1 b.b26x2 class-a_on_gp45.62020NoNoNoNo97
22b.b26x1 b.l27x1 class-a_on_gp45.84740NoNoYesNo99
23b.b2x1 b.l27x1 class-a_on_gp24.28520YesNoYesNo89
24b.b2x1 b.l3x1 class-a_on_gp24.64380YesNoNoNo89
25b.l3x1 b.l5x5 class-a_on_gp24.87310NoNoYesNo99
26G.h2s4.01 b.l5x5 class-a_on_gp25.06810YesNoYesNo99
27G.S1.05 G.h2s4.01 class-a_on_gp26.29730NoNoYesNo99
28G.S1.05 G.S1.07 class-a_on_gp67.46720NoNoNoNo99
29G.S1.07 G.S4.04 class-a_on_gp67.6790NoNoYesNo99
30G.S4.04 G.S4.06 class-a_on_gp28.33080YesNoNoNo97
31G.H4.15 G.S4.06 class-a_on_gp28.40910YesNoNoNo87
32G.H3.06 G.H4.15 class-a_on_gp57.05070NoNoYesNo68
33G.H3.06 G.hgh4.02 class-a_on_gp86.02180NoNoYesNo69
34G.hgh4.01 G.hgh4.02 class-a_on_gp42.6530NoNoYesNo59
35G.hgh4.01 G.s4h3.04 class-a_on_gp42.63620NoNoYesNo58
36G.HG.07 G.s4h3.04 class-a_on_gp99.88990NoNoYesNo98
37G.HG.07 G.s4h3.02 class-a_on_gp1000NoNoNoNo99
38G.s4h3.02 G.s5hg.01 class-a_on_gp99.92880NoNoYesNo99
39G.S5.07 G.s5hg.01 class-a_on_gp99.45220YesNoYesNo99
40G.H1.04 G.S5.07 class-a_on_gp49.49210NoNoYesNo79
41G.H1.04 G.S5.05 class-a_on_gp49.38480NoNoYesNo79
42G.S5.03 G.S5.05 class-a_on_gp86.80520NoNoYesNo99
43G.H5.10 G.S5.03 class-a_on_gp86.64180NoNoNoNo69
44G.H5.10 G.S6.02 class-a_on_gp86.56010NoNoYesNo68
45G.H3.17 b.l27x1 class-a_on_gp22.89680YesNoYesNo49
46G.H3.15 G.H3.17 class-a_on_gp40.53550NoNoYesNo84
47G.H3.15 G.H3.18 class-a_on_gp40.64680NoNoYesNo89
48G.H3.18 G.S4.02 class-a_on_gp40.86720YesNoNoNo98
49G.S1.05 G.S4.02 class-a_on_gp41.09270NoNoNoNo98
50G.H3.09 G.S4.04 class-a_on_gp70.91650YesNoYesNo99
51G.H3.09 G.H4.15 class-a_on_gp28.62010YesNoYesNo98
52G.H3.09 G.h4s6.01 class-a_on_gp28.62610YesNoNoNo94
53G.H3.06 G.h4s6.01 class-a_on_gp28.95790NoNoNoNo64
54G.HG.15 G.hgh4.02 class-a_on_gp43.01740NoNoYesNo79
55G.HG.15 G.s4h3.04 class-a_on_gp42.93850NoNoYesNo78
56G.H3.09 G.S5.04 class-a_on_gp14.29110YesNoYesNo99
57G.S5.04 G.S5.06 class-a_on_gp14.35980YesNoNoNo98
58G.S5.06 G.s4h3.01 class-a_on_gp14.59660NoNoNoNo87
59G.HG.04 G.s4h3.01 class-a_on_gp14.61590YesNoNoNo97
60G.HG.04 G.s4h3.04 class-a_on_gp14.64490YesNoYesNo98
61G.S5.07 G.s6h5.01 class-a_on_gp49.87610YesNoNoNo99
62G.S5.05 G.s6h5.01 class-a_on_gp49.36910YesNoNoNo99
63b.b4x6 b.l1x3 class-a_on_gp10.02760YesNoYesNo99
64G.S4.03 G.S5.05 class-a_on_gp13.22370NoNoYesNo79
65G.S1.06 G.S4.03 class-a_on_gp10.50360YesNoNoNo97
66G.H2.04 G.H2.07 class-a_on_gp31.19030NoNoYesNo99
67G.H2.04 G.H3.08 class-a_on_gp31.35630NoNoNoNo99
68G.H3.08 G.S4.04 class-a_on_gp31.46350NoNoYesNo99
69G.H2.07 b.l9x6 class-a_on_gp31.49560YesNoYesNo98
70G.H2.06 b.l9x6 class-a_on_gp24.81730YesNoYesNo98
71G.H2.06 b.l17x6 class-a_on_gp24.00280YesNoYesNo99
72b.l17x5 b.l17x6 class-a_on_gp23.84520NoNoYesNo69
73b.l17x5 b.l19x2 class-a_on_gp23.73180NoNoYesNo69
74b.l17x3 b.l19x2 class-a_on_gp16.31810YesNoYesNo99
75b.b17x7 b.b20x6 class-a_on_gp18.01870YesNoYesNo86
76b.b17x7 b.b21x1 class-a_on_gp17.31720YesNoYesNo87
77b.1x19 b.b21x1 class-a_on_gp15.12590NoNoYesNo67
78b.1x15 b.1x19 class-a_on_gp13.14380NoNoNoNo76
79b.1x12 b.1x15 class-a_on_gp12.57450NoNoNoNo67
80b.b20x4 b.b20x6 class-a_on_gp12.95360YesNoYesNo86
81G.H3.17 b.l25x6 class-a_on_gp17.09330YesNoYesNo48
82b.l23x1 b.l25x6 class-a_on_gp12.60930YesNoYesNo68
83b.l21x7 b.l23x1 class-a_on_gp12.39410NoNoYesNo56
84b.l21x7 b.l23x2 class-a_on_gp12.16070NoNoNoNo58
85b.b23x6 b.l23x2 class-a_on_gp11.69350YesNoNoNo78
86b.b23x6 b.b24x6 class-a_on_gp10.28920YesNoYesNo78
87b.b21x7 b.b24x6 class-a_on_gp10.06990YesNoYesNo58
88b.b2x5 b.l4x1 class-a_on_gp21.49470YesNoNoNo75
89b.l4x1 g.ctx16 class-a_on_gp21.26670NoNoYesNo50
90b.l4x2 g.ctx16 class-a_on_gp17.22690YesNoYesNo40
91b.l2x5 b.l4x2 class-a_on_gp16.73640NoNoYesNo54
92b.l2x3 b.l2x5 class-a_on_gp16.03620NoNoNoNo85
93b.b3x1 b.l2x3 class-a_on_gp15.80720NoNoNoNo58
94b.b3x1 b.b6x5 class-a_on_gp15.57830NoNoYesNo56
95b.b2x4 b.b6x5 class-a_on_gp12.51360NoNoYesNo66
96b.b10x4 b.b2x4 class-a_on_gp12.28320NoNoNoNo66
97b.1x12 g.h1x11 class-a_on_gp10.10130NoNoNoNo60
983x46 3x50 class-a_on_gp11.79440NoNoYesYes99
99Lig NT Shared10.981428.9758YesYesYesYes05
1002x42 3x46 Shared11.703435.0403YesYesNoNo79
1017x45 7x49 Shared22.13951.0523NoYesYesYes99
1026x48 7x45 Shared21.785648.3975YesYesNoYes89
1036x44 6x48 Shared21.732839.4127YesYesYesYes98
104E2 Lig Shared17.157553.7711YesYesYesYes40
1051x39 7x42 class-a_off3.582519.0027YesYesYesYes77
1067x42 Lig class-a_off0.049593958.5018YesYesYesYes70
107E3 NT class-a_off4.9411317.5473YesYesYesYes25
1082x57 7x42 class-a_off0.71690112.0298NoYesYesYes77
1091x50 2x50 class-a_off1.26035100NoYesYesYes99
1102x50 7x46 class-a_off6.2280254.8138YesYesNoNo99
1112x53 7x46 class-a_off6.0520754.8042YesNoNoNo79
1122x53 7x42 class-a_off4.6467355.1881YesNoYesYes77
1132x50 7x49 class-a_off7.788850.0992YesYesYesYes99
1146x48 Lig class-a_off086.9307YesYesYesYes80
1151x53 2x47 class-a_off0.35837195.1702NoNoNoNo99
1161x50 2x47 class-a_off095.8738NoYesNoNo99
1171x60 I1x50 class-a_off2.3155315.7657YesYesNoNo57
1188x50 I1x50 class-a_off2.4625928.1026YesYesNoNo87
1197x53 8x50 class-a_off041.2199YesYesYesYes98
1201x53 7x53 class-a_off094.2682NoNoYesYes99
1212x40 I1x50 class-a_off012.2409YesYesNoNo87
1222x38 3x49 class-a_off012.3912NoNoNoNo68
1233x49 3x50 class-a_off019.3961NoNoYesYes89
1243x50 6x37 class-a_off033.94YesYesNoNo98
1253x46 6x37 class-a_off034.6245NoNoNoNo98
1262x42 4x46 class-a_off035.9807YesYesNoNo77
1272x45 4x46 class-a_off0.35878436.2494NoNoNoNo97
1282x45 3x42 class-a_off2.1525437.5288NoNoNoNo98
1293x42 4x49 class-a_off1.4350837.7719NoNoNoNo87
1303x41 4x49 class-a_off1.0763338.2773NoNoNoNo57
1313x41 5x50 class-a_off039.7742NoNoNoNo59
1323x40 5x50 class-a_off0.71824641.2327NoNoNoNo79
1333x40 6x44 class-a_off0.88911941.7125NoNoYesYes79
1343x50 6x33 class-a_off065.7433YesYesNoNo98
1356x33 7x59 class-a_off066.6357NoNoNoNo80
1367x58 7x59 class-a_off067.1283NoNoNoNo00
1377x57 7x58 class-a_off067.6401NoNoNoNo00
1387x53 7x57 class-a_off068.1711YesYesNoNo90
1393x25 E1x50 class-a_off4.9013412.8774NoNoYesYes98
1403x25 E2 class-a_off5.6136615.4107NoNoYesYes94
1413x33 Lig class-a_off3.8569511.7451NoNoYesYes40
1425x39 5x43 class-a_off0.35786410.0947NoNoNoNo65
1435x39 E2 class-a_off0.35830818.5357NoNoYesYes64
1445x58 6x37 class-a_off2.2037412.5096YesYesNoNo98
1453x50 6x34 class-a_off067.848YesYesNoNo96
1463x51 5x61 class-a_off037.113NoYesNoNo78
1475x61 6x34 class-a_off066.1688NoNoNoNo86
1483x51 5x57 class-a_off0.54005317.0963NoYesNoNo78
1493x54 5x61 class-a_off0.18002629.9994NoNoNoNo88
1506x51 6x52 class-a_off0.37377221.0018YesNoNoNo67
1516x51 Lig class-a_off0.72750622.1885YesNoYesYes60
1525x47 6x52 class-a_off0.90231911.8635YesYesNoNo87
1533x54 5x65 class-a_off023.3879NoNoNoNo88
1545x65 6x31 class-a_off021.472NoNoNoYes84
1556x40 7x49 class-a_off010.1555NoNoYesYes89
1566x54 7x34 class-a_off0.35668415.4139NoNoYesYes54
1576x57 6x61 class-a_off0.35646911.9882NoNoNoNo43
1586x61 E3 class-a_off1.005913.8946NoNoYesYes32
1592x38 4x42 class-a_off011.1086NoNoNoNo67
1603x48 5x57 class-a_off0.36004615.174NoNoNoNo68
1614x41 I2x56 class-a_off0.86757310.2322NoNoNoNo57
1623x52 I2x56 class-a_off011.2973NoNoNoNo47
1633x48 3x52 class-a_off0.18002613.2453NoNoNoNo64
1646x57 7x30 class-a_off010.2034NoNoNoNo44
1656x28 6x31 class-a_off010.8751NoNoNoYes44

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
E3NTShared6.018572.577971221
NTNTShared41.283721.75921211
E2NTShared17.20914.23511211
7x31NTShared4.154252.279221021
1x352x64class-a_off5.2577700021
1x392x57class-a_off4.0092101022
1x397x42Shared3.828343.640461021
2x577x42Shared5.768074.977091021
2x603x28Shared4.03312.846931212
3x25E2Shared4.369862.787151221
3x26E2Shared4.881392.794221221
3x32LigShared9.025665.732581210
3x334x57Shared3.96413.769721212
3x33LigShared4.922566.120321210
3x366x48Shared6.431213.693950211
3x406x44Shared7.277583.347560222
4x605x39Shared7.141085.707270222
5x39E2Shared9.715036.812241221
E2E2x52Shared8.156745.455041211
E2E2Shared61.757751.56021211
5x36E2Shared12.16018.713610021
E2E2x51Shared9.605668.132191211
7x34E2class-a_off4.1519201211
E2LigShared6.299339.562311210
E2x52LigShared5.080736.361551210
6x58E2class-a_off5.1932601211
6x446x48Shared10.94786.548461221
6x487x41Shared6.820994.431881212
6x487x45Shared6.506338.338121212
6x48Ligclass-a_off4.9148601210
6x516x55Shared5.029135.189111211
6x51LigShared10.28966.927941210
6x547x34Shared4.067783.468650021
6x547x37Shared4.825343.530230022
6x58E3class-a_off3.9265701212
6x587x34Shared5.239363.156831211
E3E3Shared3.985944.497191222
7x347x38Shared4.495323.180281211
7x42LigShared4.127574.495931210
7x38LigShared7.445746.796511210
2x60LigShared6.289224.152481210
3x29LigShared6.112962.955341210
1x351x39Shared4.737384.183920022
2x537x42Shared4.335633.109430021
3x22E2Shared7.926075.914930221
3x294x65Shared3.95343.926481212
3x334x61class-a_off5.572601212
4x64E2Shared5.398266.784521221
5x406x55Shared4.67633.485810021
6x447x45class-a_off4.5777401222
6x55LigShared4.189043.109251210
E1x49E2Shared4.725762.82031221
LigNTShared5.620354.135141201
5x395x43Shared3.80884.841011221
3x375x43Shared3.662993.678290021
6x516x52Shared3.401433.526841212
1x32NTShared3.216092.037481221
2x563x32Shared2.972323.792840021
5x336x62Shared2.943391.001310021
5x35E2Shared2.817482.500661221
5x325x35class-a_off2.1086500222
6x62Ligclass-a_off1.9140701210
4x63E2class-a_off1.6753700021
5x38E2Shared1.637881.649120021
7x307x32class-a_off1.2252300022
7x24NTShared1.148810.8674050021
4x68E2Shared1.092570.328780021
1x29NTclass-a_off0.9938101021
E1x501NTShared0.4709290.2930320021
E1x48NTShared0.3497860.1157861221
5x31E2class-a_off0.29186100021
5x28NTclass-a_off0.041142900221
2x68E2class-a_off0.033928600021
4x69E2Shared0.03320.02181550021
3x36Ligclass-a_on_gp04.502520210
3x406x48class-a_on_gp08.371320221
4x60E2class-a_on_gp04.347320221
5x43Ligclass-a_on_gp04.145560210
6x517x37class-a_on_gp03.32291212
6x517x38class-a_on_gp02.963011211
3x223x26class-a_on_gp02.864220222
2x64Ligclass-a_on_gp02.791560010
2x533x32class-a_on_gp02.858570021
7x387x42class-a_on_gp02.852221211
7x34Ligclass-a_on_gp03.656081210
E2x51Ligclass-a_on_gp04.397330210
6x58Ligclass-a_on_gp02.90741210
4x634x64class-a_on_gp02.269010022
6x587x30class-a_on_gp01.823261212
7x28NTclass-a_on_gp01.739860221
7x32NTclass-a_on_gp01.678420221
6x62E2class-a_on_gp01.224641211
5x32E2class-a_on_gp01.195520221
5x315x35class-a_on_gp00.6662280022
5x27E2class-a_on_gp00.0560870221
5x28E2class-a_on_gp00.03682190221
3x29Ca5class-a_on_gp00.0356461212

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
class-a_on_gp sensory_on_gp
alicarboxylic_on_gp
amine_on_gp
lipid_on_gp
nucleotide_on_gp
peptide_on_gp
protein_on_gp
class-a_off sensory_off
alicarboxylic_off
amine_off
lipid_off
nucleotide_off
peptide_off
protein_off
Network Difference
Value class-a_on_gp class-a_off
Imin 2.75526 3.82493
Number of Linked Nodes 1203 336
Number of Specific Nodes 870 (72.32%) 3  (0.89%)
Number of Shared Nodes 333 (27.68%) 333  (99.11%)
Number of Links 1372 352
Number of Specific Links 1167 (85.06%) 147  (41.76%)
Number of Shared Links 205 (14.94%) 205  (58.24%)
Number of Hubs 194 34
Number of Specific Hubs 171 (88.14%) 11  (32.35%)
Number of Shared Hubs 23 (11.86%) 23  (67.65%)
Average % Shared Neighbours (Jaccard) 12.85
Average % Shared Neighbours (Otsuka) 15.05
Average % Shared Neighbours (Overlap Coefficient) 17.15
Average % Shared Cliques (k3-6) 75.96
Graphlets Similarity 0.46838
Paths Difference
Value class-a_on_gp class-a_off
Number Of Nodes in MetaPath 98 67
Specific Nodes in MetaPath 85 (86.73%) 54  (80.60%)
Shared Nodes in MetaPath 333 (27.68%) 333  (27.68%)
Number Of Links MetaPath 104 67
Specific Links in MetaPath 98 (94.23%) 61  (91.04%)
Shared Links in MetaPath 205 (14.94%) 205  (14.94%)
Number of Shortest Paths 16754693 68055
Length Of Smallest Path 3 3
Average Path Length 46.9784 15.7677
Length of Longest Path 72 34
Minimum Path Strength 0.203775 0.619216
Average Path Strength 4.68945 4.51923
Maximum Path Strength 21.0844 14.6846
Minimum Path Correlation 0.701657 0.701756
Average Path Correlation 0.989998 0.888535
Maximum Path Correlation 1 0.984253
Minimum % Of Corr. Nodes 1.49254 3.22581
Average % Of Corr. Nodes 17.9162 31.6811
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 57.2801 39.3846
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download class-a_off_on_gp.zip<



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