psnGPCR

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Orange: nodes, hubs and links specific of lpl_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of lpl_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	lpl_off Int. Strength	lpl_on Int. Strength	lpl_off Hub1?	lpl_on Hub1?	lpl_off Hub2?	lpl_on Hub2?	ConSurf1	ConSurf2
1	3x21	NT	lpl_off	100	0	No	No	Yes	Yes	7	6
2	1x50	2x47	lpl_off	100	0	Yes	Yes	No	No	9	9
3	2x39	3x50	lpl_off	100	0	No	No	Yes	No	8	9
4	2x40	6x33	lpl_off	100	0	No	Yes	No	No	9	8
5	2x46	7x49	lpl_off	100	0	Yes	Yes	No	No	9	9
6	2x57	2x60	lpl_off	100	0	Yes	Yes	No	No	6	5
7	2x57	3x32	lpl_off	100	0	Yes	Yes	No	No	6	6
8	2x63	E1x52	lpl_off	100	0	No	No	No	No	4	5
9	3x32	Lig	lpl_off	100	0	No	No	Yes	Yes	6	0
10	3x33	5x43	lpl_off	100	0	Yes	Yes	Yes	No	5	6
11	3x36	5x47	lpl_off	100	0	No	No	Yes	Yes	6	7
12	3x43	6x44	lpl_off	100	0	No	No	Yes	Yes	9	9
13	3x46	6x37	lpl_off	100	0	No	Yes	No	No	8	8
14	3x49	3x50	lpl_off	100	0	Yes	No	Yes	No	9	9
15	3x50	3x53	lpl_off	100	0	Yes	No	No	No	9	8
16	3x50	6x34	lpl_off	100	0	Yes	No	No	No	9	8
17	4x59	4x60	lpl_off	100	0	Yes	No	No	No	5	5
18	4x59	5x39	lpl_off	100	0	Yes	No	Yes	No	5	7
19	5x42	E2	lpl_off	100	0	No	No	Yes	Yes	5	4
20	5x40	E2	lpl_off	100	0	No	No	Yes	Yes	6	4
21	5x39	5x43	lpl_off	100	0	Yes	No	Yes	No	7	6
22	5x43	5x47	lpl_off	100	0	Yes	No	Yes	Yes	6	7
23	5x54	6x41	lpl_off	100	0	No	No	Yes	No	8	7
24	5x58	6x38	lpl_off	100	0	Yes	Yes	No	No	9	5
25	5x60	5x63	lpl_off	100	0	No	No	No	No	5	3
26	5x60	5x64	lpl_off	100	0	No	No	No	No	5	6
27	6x29	8x49	lpl_off	100	0	No	No	No	No	6	7
28	6x33	8x47	lpl_off	100	0	No	No	No	No	8	8
29	6x36	8x47	lpl_off	100	0	No	No	No	No	9	8
30	6x39	7x56	lpl_off	100	0	No	No	No	No	6	7
31	6x40	7x49	lpl_off	100	0	No	No	No	No	8	9
32	6x48	6x52	lpl_off	100	0	Yes	Yes	Yes	Yes	8	6
33	6x48	Lig	lpl_off	100	0	Yes	Yes	Yes	Yes	8	0
34	7x45	7x48	lpl_off	100	0	Yes	Yes	No	No	9	5
35	7x53	8x50	lpl_off	100	0	No	Yes	Yes	No	9	8
36	7x54	8x54	lpl_off	100	0	No	No	Yes	Yes	7	7
37	8x47	8x50	lpl_off	100	0	No	No	Yes	No	8	8
38	8x49	I1x49	lpl_off	100	0	No	No	No	No	7	6
39	2x38	3x49	lpl_off	50	0	No	No	Yes	No	7	9
40	2x49	3x39	lpl_off	50	0	No	No	No	No	8	9
41	2x39	2x43	lpl_off	50	0	No	No	No	No	8	8
42	6x35	6x39	lpl_off	50	0	No	No	No	No	7	6
43	1x39	2x61	lpl_off	50	0	No	No	No	No	6	5
44	4x41	I2x56	lpl_off	50	0	No	No	No	No	5	7
45	6x40	7x52	lpl_off	37.5	0	No	No	No	No	8	8
46	2x48	4x50	lpl_off	50	0	No	No	Yes	Yes	5	9
47	3x43	6x41	lpl_off	50	0	No	No	Yes	No	9	7
48	7x54	8x51	lpl_off	50	0	No	No	No	No	7	8
49	7x33	7x37	lpl_off	50	0	No	No	Yes	No	4	4
50	3x37	5x47	lpl_off	50	0	No	Yes	Yes	Yes	6	7
51	1x53	7x53	lpl_off	50	0	No	No	No	Yes	9	9
52	3x50	6x30	lpl_off	50	0	Yes	No	No	No	9	7
53	2x46	3x39	lpl_off	0	0	Yes	Yes	No	No	9	9
54	2x53	7x46	lpl_off	12.5	0	No	No	No	No	8	9
55	6x33	8x49	lpl_off	50	0	No	No	No	No	8	7
56	2x52	3x34	lpl_off	50	0	No	No	No	No	6	5
57	7x29	7x33	lpl_off	50	0	No	No	No	No	3	4
58	5x37	E2	lpl_off	25	0	No	No	Yes	Yes	3	4
59	8x59	CT	lpl_off	50	0	No	No	No	No	4	5
60	E1x49	NT	lpl_off	50	0	No	No	Yes	Yes	4	6
61	3x34	4x57	lpl_off	0	0	No	No	No	No	5	6
62	1x42	7x42	lpl_off	50	0	No	No	No	No	6	7
63	2x59	3x27	lpl_off	50	0	No	No	No	No	7	4
64	4x38	I2x53	lpl_off	50	0	No	No	No	No	7	7
65	6x47	7x40	lpl_off	0	0	No	No	No	No	8	7
66	1x33	NT	lpl_off	50	0	No	No	Yes	Yes	4	6
67	3x48	3x52	lpl_off	0	0	No	No	No	No	6	4
68	1x42	7x43	lpl_off	0	0	No	No	No	No	6	6
69	3x47	5x57	lpl_off	0	0	No	No	No	No	8	7
70	5x52	5x56	lpl_off	50	0	No	No	No	No	4	4
71	2x56	3x32	lpl_off	0	0	No	No	No	No	4	6
72	6x57	6x61	lpl_off	50	0	No	No	No	No	4	4
73	6x26	I2x51	lpl_off	50	0	No	No	No	No	4	7
74	5x44	6x56	lpl_off	50	0	No	No	No	No	5	6
75	5x42	5x46	lpl_off	50	0	No	No	No	No	5	5
76	1x52	8x57	lpl_off	50	0	No	No	No	No	7	6
77	2x38	I2x53	lpl_off	37.5	0	No	No	No	No	7	7
78	1x36	1x40	lpl_off	0	0	No	No	Yes	Yes	5	3
79	4x58	4x61	lpl_off	0	0	No	No	No	No	4	5
80	1x55	8x57	lpl_off	25	0	No	No	No	No	4	6
81	1x36	1x37	lpl_off	12.5	0	No	No	No	No	5	5
82	2x37	I2x52	lpl_off	25	0	No	No	No	No	7	4
83	6x27	6x30	lpl_off	0	0	No	No	No	No	4	7
84	4x40	I2x55	lpl_off	12.5	0	Yes	No	No	No	4	4
85	3x30	E2	lpl_off	0	0	No	No	Yes	Yes	6	4
86	6x27	6x31	lpl_off	0	0	No	No	No	No	4	5
87	1x58	1x59	lpl_off	0	0	No	No	No	No	3	6
88	6x30	I2x51	lpl_off	12.5	0	No	No	No	No	7	7
89	I2x54	I2x56	lpl_off	12.5	0	No	No	No	No	4	7
90	7x30	7x37	lpl_off	0	0	No	No	Yes	No	3	4
91	7x32	E3	lpl_off	0	0	No	No	Yes	Yes	1	2
92	4x45	4x49	lpl_off	0	0	No	No	No	No	6	6
93	1x38	1x42	lpl_off	0	0	No	No	No	No	5	6
94	4x40	4x43	lpl_off	0	0	Yes	No	No	No	4	2
95	6x24	6x27	lpl_off	0	0	No	No	No	No	2	4
96	6x24	6x28	lpl_off	0	0	No	No	No	Yes	2	5
97	6x25	6x26	lpl_off	0	0	No	No	No	No	4	4
98	6x38	6x42	lpl_off	0	0	No	No	No	No	5	5
99	6x32	6x35	lpl_off	12.5	0	No	No	No	No	7	7
100	4x59	4x62	lpl_off	0	0	Yes	No	No	No	5	4
101	1x29	1x32	lpl_off	0	0	No	No	No	No	3	4
102	8x51	8x55	lpl_off	0	0	No	No	No	No	8	3
103	4x47	4x51	lpl_off	0	0	No	No	No	No	4	4
104	I2x50	I2x51	lpl_off	12.5	0	No	No	No	No	8	7
105	5x49	5x50	lpl_off	0	0	No	No	No	No	5	8
106	5x53	5x57	lpl_off	0	0	No	No	No	No	6	7
107	3x52	3x56	lpl_off	0	0	No	No	No	No	4	6
108	8x58	8x59	lpl_off	0	0	No	No	No	No	5	4
109	5x49	5x52	lpl_off	0	0	No	No	No	No	5	4
110	8x52	8x56	lpl_off	0	0	No	No	No	No	5	4
111	8x52	8x55	lpl_off	0	0	No	No	No	No	5	3
112	NT	NT	Shared	100	100	Yes	Yes	Yes	Yes	6	6
113	E2	NT	Shared	100	100	Yes	Yes	Yes	Yes	4	6
114	3x22	NT	Shared	100	100	No	No	Yes	Yes	3	6
115	E1x501	NT	Shared	100	100	No	No	Yes	Yes	5	6
116	3x25	NT	Shared	100	100	Yes	Yes	Yes	Yes	9	6
117	E1x50	NT	Shared	100	100	No	No	Yes	Yes	5	6
118	Lig	NT	Shared	100	100	Yes	Yes	Yes	Yes	0	6
119	E3	NT	Shared	100	100	Yes	Yes	Yes	Yes	2	6
120	1x31	NT	Shared	100	50	No	No	Yes	Yes	2	6
121	1x39	7x39	Shared	100	100	No	No	No	Yes	6	5
122	1x43	2x58	Shared	100	100	No	No	No	No	5	6
123	1x45	1x49	Shared	100	50	No	No	No	No	4	8
124	1x46	7x47	Shared	100	100	No	Yes	No	No	7	7
125	1x47	2x51	Shared	100	100	No	No	No	No	6	6
126	1x49	7x50	Shared	100	100	No	No	No	No	8	9
127	1x50	2x50	Shared	100	100	Yes	Yes	No	Yes	9	9
128	1x50	7x50	Shared	100	100	Yes	Yes	No	No	9	9
129	1x51	2x51	Shared	100	100	No	No	No	No	4	6
130	1x52	8x54	Shared	100	100	No	No	Yes	Yes	7	7
131	1x60	I1x50	Shared	100	100	No	No	No	Yes	6	8
132	1x60	8x53	Shared	100	100	No	No	No	No	6	7
133	2x40	I1x50	Shared	100	100	No	Yes	No	Yes	9	8
134	8x50	I1x50	Shared	100	100	Yes	No	No	Yes	8	8
135	2x41	I1x51	Shared	100	100	No	No	No	No	4	7
136	2x39	3x49	Shared	100	100	No	No	Yes	No	8	9
137	2x42	3x45	Shared	100	7.29167	No	Yes	No	No	8	7
138	2x42	3x49	Shared	100	100	No	Yes	Yes	No	8	9
139	2x43	7x53	Shared	100	29.1667	No	No	No	Yes	8	9
140	2x45	3x42	Shared	100	100	No	No	No	No	9	8
141	2x45	4x46	Shared	100	100	No	No	No	No	9	7
142	2x45	4x50	Shared	100	100	No	No	Yes	Yes	9	9
143	2x46	3x42	Shared	100	100	Yes	Yes	No	No	9	8
144	2x46	3x43	Shared	100	100	Yes	Yes	No	No	9	9
145	2x50	7x46	Shared	100	100	No	Yes	No	No	9	9
146	2x50	7x49	Shared	100	100	No	Yes	No	No	9	9
147	2x52	4x50	Shared	100	100	No	No	Yes	Yes	6	9
148	2x57	2x61	Shared	100	100	Yes	Yes	No	No	6	5
149	2x57	7x42	Shared	100	100	Yes	Yes	No	No	6	7
150	2x60	3x28	Shared	100	100	No	No	Yes	Yes	5	6
151	2x60	Lig	Shared	100	100	No	No	Yes	Yes	5	0
152	3x28	E1x50	Shared	100	100	Yes	Yes	No	No	6	5
153	3x24	E1x52	Shared	100	100	No	No	No	No	4	5
154	3x28	E1x52	Shared	100	100	Yes	Yes	No	No	6	5
155	3x21	3x24	Shared	100	100	No	No	No	No	7	4
156	3x25	3x28	Shared	100	100	Yes	Yes	Yes	Yes	9	6
157	3x25	3x29	Shared	100	100	Yes	Yes	Yes	Yes	9	5
158	3x25	E2	Shared	100	100	Yes	Yes	Yes	Yes	9	4
159	3x26	E2	Shared	100	100	No	No	Yes	Yes	6	4
160	3x28	3x29	Shared	100	100	Yes	Yes	Yes	Yes	6	5
161	3x28	Lig	Shared	100	100	Yes	Yes	Yes	Yes	6	0
162	3x29	E2	Shared	100	100	Yes	Yes	Yes	Yes	5	4
163	3x29	Lig	Shared	100	100	Yes	Yes	Yes	Yes	5	0
164	3x33	E2	Shared	100	100	Yes	Yes	Yes	Yes	5	4
165	3x33	5x39	Shared	100	100	Yes	Yes	Yes	No	5	7
166	3x33	Lig	Shared	100	100	Yes	Yes	Yes	Yes	5	0
167	3x36	6x48	Shared	100	100	No	No	Yes	Yes	6	8
168	3x37	4x53	Shared	100	75	No	Yes	No	No	6	8
169	3x37	4x56	Shared	100	100	No	Yes	No	No	6	5
170	3x38	4x50	Shared	100	100	No	No	Yes	Yes	7	9
171	3x40	5x47	Shared	100	100	No	No	Yes	Yes	7	7
172	3x40	5x50	Shared	100	100	No	No	No	No	7	8
173	3x41	4x49	Shared	100	100	No	No	No	No	5	6
174	3x42	4x49	Shared	100	100	No	No	No	No	8	6
175	3x44	3x48	Shared	100	100	No	Yes	No	No	7	6
176	3x44	5x54	Shared	100	100	No	Yes	No	No	7	8
177	3x47	5x58	Shared	100	100	No	No	Yes	Yes	8	9
178	3x51	5x57	Shared	100	100	No	Yes	No	No	8	7
179	3x51	5x60	Shared	100	100	No	Yes	No	No	8	5
180	3x51	5x61	Shared	100	100	No	Yes	No	No	8	9
181	4x40	4x44	Shared	100	4.6875	Yes	No	No	No	4	3
182	4x60	E2	Shared	100	100	No	No	Yes	Yes	5	4
183	4x60	5x39	Shared	100	100	No	No	Yes	No	5	7
184	5x36	E2	Shared	100	100	No	No	Yes	Yes	4	4
185	5x38	E2	Shared	100	100	No	No	Yes	Yes	4	4
186	5x39	E2	Shared	100	100	Yes	No	Yes	Yes	7	4
187	E2	E2	Shared	100	100	Yes	Yes	Yes	Yes	4	4
188	6x58	E2	Shared	100	100	No	No	Yes	Yes	4	4
189	6x54	E2	Shared	100	100	No	No	Yes	Yes	4	4
190	7x34	E2	Shared	100	100	No	No	Yes	Yes	4	4
191	E2	Lig	Shared	100	100	Yes	Yes	Yes	Yes	4	0
192	5x36	5x38	Shared	100	100	No	No	No	No	4	4
193	5x40	6x55	Shared	100	100	No	No	No	No	6	6
194	5x41	6x59	Shared	100	100	No	No	No	Yes	5	4
195	5x43	Lig	Shared	100	100	Yes	No	Yes	Yes	6	0
196	5x47	6x52	Shared	100	100	Yes	Yes	Yes	Yes	7	6
197	5x51	6x44	Shared	100	100	No	Yes	Yes	Yes	5	9
198	5x58	6x37	Shared	100	100	Yes	Yes	No	No	9	8
199	6x36	7x56	Shared	100	100	No	No	No	No	9	7
200	6x44	6x48	Shared	100	100	Yes	Yes	Yes	Yes	9	8
201	6x44	7x45	Shared	100	100	Yes	Yes	Yes	Yes	9	9
202	6x47	7x45	Shared	100	100	No	No	Yes	Yes	8	9
203	6x48	7x41	Shared	100	100	Yes	Yes	No	No	8	7
204	6x48	7x45	Shared	100	100	Yes	Yes	Yes	Yes	8	9
205	6x50	7x37	Shared	100	100	No	No	Yes	No	9	4
206	6x54	7x37	Shared	100	100	No	No	Yes	No	4	4
207	6x55	Lig	Shared	100	100	No	No	Yes	Yes	6	0
208	6x58	7x31	Shared	100	100	No	No	No	No	4	3
209	6x61	E3	Shared	100	100	No	No	Yes	Yes	4	2
210	E3	E3	Shared	100	100	Yes	Yes	Yes	Yes	2	2
211	7x33	7x36	Shared	100	50	No	No	No	No	4	3
212	7x35	Lig	Shared	100	100	No	No	Yes	Yes	3	0
213	7x38	Lig	Shared	100	100	No	No	Yes	Yes	5	0
214	7x34	NT	Shared	100	100	No	No	Yes	Yes	4	6
215	E1x48	NT	Shared	100	100	No	No	Yes	Yes	4	6
216	3x55	5x64	Shared	100	100	No	No	No	No	6	6
217	5x37	6x59	Shared	100	100	No	No	No	Yes	3	4
218	7x34	Lig	Shared	100	100	No	No	Yes	Yes	4	0
219	7x55	7x56	Shared	100	100	No	No	No	No	6	7
220	2x37	2x38	Shared	87.5	51.5625	No	No	No	No	7	7
221	5x51	6x45	Shared	50	100	No	Yes	No	Yes	5	6
222	6x39	7x52	Shared	50	4.6875	No	No	No	No	6	8
223	5x58	6x41	Shared	50	100	Yes	Yes	Yes	No	9	7
224	4x38	4x41	Shared	50	50	No	No	No	No	7	5
225	1x50	2x51	Shared	50	100	Yes	Yes	No	No	9	6
226	6x51	Lig	Shared	50	75	No	No	Yes	Yes	6	0
227	2x42	4x42	Shared	25	100	No	Yes	No	Yes	8	7
228	2x59	2x63	Shared	50	100	No	No	No	No	7	4
229	1x40	2x58	Shared	50	100	Yes	Yes	No	No	3	6
230	1x49	7x51	Shared	50	16.6667	No	No	No	No	8	6
231	1x32	NT	Shared	50	100	No	No	Yes	Yes	4	6
232	8x48	8x51	Shared	50	16.6667	No	No	No	No	6	8
233	E1	Lig	Shared	50	100	No	No	Yes	Yes	0	0
234	3x54	5x61	Shared	50	100	No	No	No	No	8	9
235	1x47	2x55	Shared	50	100	No	No	No	No	6	5
236	3x21	3x23	Shared	50	100	No	No	No	No	7	2
237	1x57	2x40	Shared	50	50	No	No	No	Yes	7	9
238	1x43	2x57	Shared	62.5	100	No	No	Yes	Yes	5	6
239	1x56	8x54	Shared	50	41.6667	No	No	Yes	Yes	8	7
240	1x46	7x46	Shared	50	100	No	Yes	No	No	7	9
241	3x41	4x52	Shared	62.5	50	No	No	No	No	5	4
242	8x50	8x54	Shared	50	50	Yes	No	Yes	Yes	8	7
243	3x26	4x61	Shared	12.5	50	No	No	No	No	6	5
244	5x44	6x52	Shared	50	50	No	No	Yes	Yes	5	6
245	2x53	3x35	Shared	12.5	50	No	No	No	No	8	6
246	6x43	7x48	Shared	0	25.5208	No	No	No	No	7	5
247	I1x48	I1x51	Shared	50	4.6875	No	No	No	No	6	7
248	1x48	1x52	Shared	50	3.125	No	No	No	No	4	7
249	1x54	2x47	Shared	0	31.25	No	No	No	No	8	9
250	2x41	4x39	Shared	50	100	No	No	No	No	4	1
251	5x62	6x34	Shared	50	100	No	Yes	No	No	6	8
252	5x48	6x52	Shared	0	25	No	No	Yes	Yes	4	6
253	1x40	1x44	Shared	0	0	Yes	Yes	No	No	3	5
254	1x57	2x44	Shared	12.5	100	No	No	No	No	7	5
255	3x34	4x54	Shared	12.5	100	No	No	No	No	5	4
256	2x64	Lig	Shared	50	50	No	No	Yes	Yes	4	0
257	E1x47	E1x48	Shared	50	62.5	No	No	No	No	4	4
258	6x49	6x50	Shared	12.5	100	No	No	No	No	6	9
259	6x53	6x57	Shared	0	8.33333	No	No	No	No	5	4
260	3x54	5x65	Shared	0	4.6875	No	No	No	No	8	8
261	3x27	3x31	Shared	12.5	50	No	No	No	No	4	4
262	1x36	2x62	Shared	12.5	50	No	No	No	No	5	6
263	1x35	7x35	Shared	12.5	100	No	No	No	No	5	3
264	5x45	5x49	Shared	0	0	No	No	No	No	4	5
265	1x46	2x54	Shared	12.5	100	No	Yes	No	No	7	7
266	4x55	4x59	Shared	0	50	No	No	Yes	No	4	5
267	2x41	4x42	Shared	12.5	100	No	No	No	Yes	4	7
268	E1x49	E1x51	Shared	12.5	100	No	No	No	No	4	1
269	4x63	E2	Shared	0	3.125	No	No	Yes	Yes	5	4
270	1x59	8x57	Shared	0	50	No	No	No	No	6	6
271	4x38	4x40	Shared	12.5	100	No	No	Yes	No	7	4
272	5x55	6x41	Shared	0	100	No	No	Yes	No	4	7
273	4x51	4x55	Shared	0	5.72917	No	No	No	No	4	4
274	6x59	6x60	Shared	0	26.5625	No	Yes	No	No	4	4
275	6x45	6x46	Shared	0	0	No	Yes	No	No	6	5
276	1x30	NT	Shared	0	50	No	No	Yes	Yes	4	6
277	4x48	4x52	Shared	0	8.33333	No	No	No	No	3	4
278	3x44	5x53	Shared	0	17.1875	No	Yes	No	No	7	6
279	1x40	1x41	Shared	0	0	Yes	Yes	No	No	3	4
280	1x34	1x38	Shared	0	25	No	No	No	No	4	5
281	1x46	1x50	lpl_on	0	100	No	Yes	Yes	Yes	7	9
282	1x59	1x60	lpl_on	0	100	No	No	No	No	6	6
283	2x38	4x42	lpl_on	0	100	No	No	No	Yes	7	7
284	2x42	3x46	lpl_on	0	100	No	Yes	No	Yes	8	8
285	2x46	2x50	lpl_on	0	100	Yes	Yes	No	Yes	9	9
286	2x46	3x46	lpl_on	0	100	Yes	Yes	No	Yes	9	8
287	2x50	3x39	lpl_on	0	100	No	Yes	No	No	9	9
288	2x57	7x38	lpl_on	0	100	Yes	Yes	No	No	6	5
289	2x58	2x62	lpl_on	0	100	No	No	No	No	6	6
290	2x63	3x28	lpl_on	0	100	No	No	Yes	Yes	4	6
291	3x25	3x26	lpl_on	0	100	Yes	Yes	No	No	9	6
292	3x36	Lig	lpl_on	0	100	No	No	Yes	Yes	6	0
293	3x37	Lig	lpl_on	0	100	No	Yes	Yes	Yes	6	0
294	3x40	6x48	lpl_on	0	100	No	No	Yes	Yes	7	8
295	3x43	7x49	lpl_on	0	100	No	No	No	No	9	9
296	3x43	7x53	lpl_on	0	100	No	No	No	Yes	9	9
297	3x44	5x50	lpl_on	0	100	No	Yes	No	No	7	8
298	3x46	3x50	lpl_on	0	100	No	Yes	Yes	No	8	9
299	3x46	7x53	lpl_on	0	100	No	Yes	No	Yes	8	9
300	3x50	7x53	lpl_on	0	100	Yes	No	No	Yes	9	9
301	3x51	3x55	lpl_on	0	100	No	Yes	No	No	8	6
302	3x52	4x41	lpl_on	0	100	No	No	No	No	4	5
303	I2x52	I2x53	lpl_on	0	100	No	No	No	No	4	7
304	4x56	5x43	lpl_on	0	100	No	No	Yes	No	5	6
305	4x59	E2	lpl_on	0	100	Yes	No	Yes	Yes	5	4
306	7x31	E2	lpl_on	0	100	No	No	Yes	Yes	3	4
307	5x46	5x50	lpl_on	0	100	No	No	No	No	5	8
308	5x47	6x48	lpl_on	0	100	Yes	Yes	Yes	Yes	7	8
309	5x51	5x55	lpl_on	0	100	No	Yes	No	No	5	4
310	5x62	5x66	lpl_on	0	100	No	Yes	No	No	6	5
311	5x62	6x33	lpl_on	0	100	No	Yes	No	No	6	8
312	5x64	5x68	lpl_on	0	100	No	No	No	No	6	7
313	5x65	6x33	lpl_on	0	100	No	No	No	No	8	8
314	5x66	6x30	lpl_on	0	100	No	No	No	No	5	7
315	6x40	7x53	lpl_on	0	100	No	No	No	Yes	8	9
316	6x50	7x40	lpl_on	0	100	No	No	No	No	9	7
317	7x32	7x33	lpl_on	0	100	No	No	No	No	1	4
318	7x43	7x48	lpl_on	0	100	No	No	No	No	6	5
319	7x45	7x49	lpl_on	0	100	Yes	Yes	No	No	9	9
320	7x52	7x53	lpl_on	0	100	No	No	No	Yes	8	9
321	2x60	3x32	lpl_on	0	100	No	No	No	No	5	6
322	3x50	5x58	lpl_on	0	100	Yes	No	Yes	Yes	9	9
323	3x55	5x60	lpl_on	0	100	No	No	No	No	6	5
324	5x47	6x44	lpl_on	0	100	Yes	Yes	Yes	Yes	7	9
325	6x45	6x49	lpl_on	0	100	No	Yes	No	No	6	6
326	7x54	8x50	lpl_on	0	100	No	No	Yes	No	7	8
327	2x38	I2x56	lpl_on	0	100	No	No	No	No	7	7
328	2x40	8x47	lpl_on	0	100	No	Yes	No	No	9	8
329	2x57	7x39	lpl_on	0	100	Yes	Yes	No	Yes	6	5
330	I2x51	I2x54	lpl_on	0	100	No	No	No	No	7	4
331	3x36	7x42	lpl_on	0	100	No	No	No	No	6	7
332	3x53	3x56	lpl_on	0	100	No	No	No	No	8	6
333	3x56	I2x54	lpl_on	0	100	No	No	No	No	6	4
334	3x37	5x43	lpl_on	0	100	No	Yes	Yes	No	6	6
335	3x56	I2x56	lpl_on	0	100	No	No	No	No	6	7
336	6x32	7x56	lpl_on	0	100	No	No	No	No	7	7
337	6x58	7x30	lpl_on	0	50	No	No	No	No	4	3
338	1x53	2x47	lpl_on	0	69.7917	No	No	No	No	9	9
339	5x40	6x59	lpl_on	0	67.1875	No	No	No	Yes	6	4
340	6x28	6x30	lpl_on	0	51.5625	No	Yes	No	No	5	7
341	2x42	4x45	lpl_on	0	50	No	Yes	No	No	8	6
342	4x56	5x42	lpl_on	0	53.125	No	No	No	No	5	5
343	3x30	3x33	lpl_on	0	50	No	No	Yes	Yes	6	5
344	5x68	I2x50	lpl_on	0	62.5	No	No	No	No	7	8
345	I1x49	I1x50	lpl_on	0	67.1875	No	No	No	Yes	6	8
346	2x49	4x50	lpl_on	0	50	No	No	Yes	Yes	8	9
347	2x40	I1x51	lpl_on	0	50	No	Yes	No	No	9	7
348	1x53	7x50	lpl_on	0	50	No	No	No	No	9	9
349	1x42	7x39	lpl_on	0	54.1667	No	No	No	Yes	6	5
350	6x28	6x31	lpl_on	0	51.5625	No	Yes	No	No	5	5
351	3x49	4x41	lpl_on	0	50	Yes	No	No	No	9	5
352	3x48	5x57	lpl_on	0	28.125	No	No	No	No	6	7
353	6x39	7x55	lpl_on	0	50	No	No	No	No	6	6
354	2x52	3x35	lpl_on	0	65.625	No	No	No	No	6	6
355	6x34	6x38	lpl_on	0	50	No	No	No	No	8	5
356	2x56	3x35	lpl_on	0	50	No	No	No	No	4	6
357	7x35	7x36	lpl_on	0	50	No	No	No	No	3	3
358	4x42	4x43	lpl_on	0	40.625	No	Yes	No	No	7	2
359	5x62	6x35	lpl_on	0	50	No	Yes	No	No	6	7
360	3x34	4x53	lpl_on	0	29.6875	No	No	No	No	5	8
361	6x52	6x56	lpl_on	0	50	Yes	Yes	No	No	6	6
362	6x57	7x30	lpl_on	0	25	No	No	No	No	4	3
363	5x69	6x29	lpl_on	0	50	No	No	No	No	0	6
364	4x62	4x63	lpl_on	0	51.5625	No	No	No	No	4	5
365	5x41	5x45	lpl_on	0	62.5	No	No	No	No	5	4
366	7x43	7x47	lpl_on	0	12.5	No	No	No	No	6	7
367	I2x54	I2x55	lpl_on	0	51.5625	No	No	No	No	4	4
368	1x38	7x39	lpl_on	0	50	No	No	No	Yes	5	5
369	5x62	5x63	lpl_on	0	12.5	No	Yes	No	No	6	3
370	1x54	2x48	lpl_on	0	41.6667	No	No	No	No	8	5
371	3x33	4x57	lpl_on	0	0	Yes	Yes	No	No	5	6
372	2x40	8x49	lpl_on	0	25	No	Yes	No	No	9	7
373	1x57	1x58	lpl_on	0	37.5	No	No	No	No	7	3
374	8x48	8x49	lpl_on	0	1.5625	No	No	No	No	6	7
375	1x37	1x40	lpl_on	0	25	No	No	Yes	Yes	5	3
376	2x56	3x31	lpl_on	0	4.16667	No	No	No	No	4	4
377	7x29	7x32	lpl_on	0	0	No	No	No	No	3	1
378	5x66	5x70	lpl_on	0	16.6667	No	No	No	No	5	0
379	E1x48	E1x49	lpl_on	0	25	No	No	No	No	4	4
380	1x55	1x59	lpl_on	0	7.29167	No	No	No	No	4	6
381	5x65	5x69	lpl_on	0	0	No	No	No	No	8	0
382	3x53	I2x53	lpl_on	0	12.5	No	No	No	No	8	7
383	5x69	6x26	lpl_on	0	12.5	No	No	No	No	0	4
384	6x42	6x45	lpl_on	0	0	No	No	No	Yes	5	6
385	6x23	6x26	lpl_on	0	12.5	No	No	No	No	0	4
386	5x56	5x60	lpl_on	0	12.5	No	No	No	No	4	5
387	5x51	5x52	lpl_on	0	0	No	Yes	No	No	5	4
388	8x54	8x55	lpl_on	0	3.125	Yes	Yes	No	No	7	3
389	6x27	6x28	lpl_on	0	15.625	No	No	No	Yes	4	5
390	1x33	1x37	lpl_on	0	12.5	No	No	No	No	4	5
391	8x48	8x52	lpl_on	0	12.5	No	No	No	No	6	5
392	4x57	4x58	lpl_on	0	0	No	No	No	No	6	4
393	6x26	I3	lpl_on	0	12.5	No	No	No	No	4	0
394	4x47	4x48	lpl_on	0	0	No	No	No	No	4	3
395	5x72	5x74	lpl_on	0	6.25	No	No	No	No	0	0
396	5x55	5x59	lpl_on	0	0	No	No	No	No	4	3
397	6x25	6x28	lpl_on	0	4.16667	No	No	No	Yes	4	5
398	5x73	I3	lpl_on	0	3.125	No	No	No	No	0	0
399	5x67	5x71	lpl_on	0	1.5625	No	No	No	No	5	0
400	6x24	6x25	lpl_on	0	4.16667	No	No	No	No	2	4
401	5x68	5x72	lpl_on	0	0	No	No	No	No	7	0
402	8x56	8x57	lpl_on	0	0	No	No	No	No	4	6
403	5x71	5x72	lpl_on	0	1.5625	No	No	No	No	0	0

Orange: nodes, hubs and links specific of lpl_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of lpl_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	lpl_off Avg Int. Strength	lpl_on Avg Int. Strength	lpl_off Num Of Links	lpl_on Num Of Links	ConSurf
1	3x49	lpl_off	50	0	4	3	9
2	3x50	lpl_off	87.5	0	5	3	9
3	4x40	lpl_off	0	0	4	2	4
4	4x59	lpl_off	0	0	4	2	5
5	5x39	lpl_off	62.5	48.4375	5	3	7
6	5x43	lpl_off	50	50	4	3	6
7	6x41	lpl_off	0	0	4	2	7
8	7x37	lpl_off	0	0	4	2	4
9	8x50	lpl_off	0	0	4	3	8
10	NT	Shared	100	100	17	14	6
11	1x40	Shared	0	0	4	4	3
12	1x50	Shared	37.5	25	4	4	9
13	2x46	Shared	0	86.9792	4	4	9
14	2x57	Shared	50	70.8333	5	5	6
15	3x25	Shared	100	100	4	5	9
16	3x28	Shared	87.5	98.4375	6	7	6
17	3x29	Shared	62.5	78.6458	4	4	5
18	3x33	Shared	62.5	67.1875	4	5	5
19	4x50	Shared	0	0	4	4	9
20	E2	Shared	100	100	20	18	4
21	5x47	Shared	100	50	5	4	7
22	5x58	Shared	0	58.3333	4	4	9
23	6x44	Shared	100	50	4	4	9
24	6x48	Shared	100	87.5	6	6	8
25	6x52	Shared	0	0	4	4	6
26	E3	Shared	50	45.8333	5	4	2
27	7x45	Shared	50	20.3125	4	4	9
28	8x54	Shared	0	0	4	4	7
29	Lig	Shared	100	100	16	16	0
30	1x46	lpl_on	0	50	3	4	7
31	I1x50	lpl_on	87.5	25	3	4	8
32	2x40	lpl_on	0	13.5417	3	5	9
33	2x42	lpl_on	0	25	3	5	8
34	2x50	lpl_on	0	73.4375	3	5	9
35	3x37	lpl_on	0	0	3	4	6
36	3x44	lpl_on	0	0	3	4	7
37	3x46	lpl_on	0	0	1	4	8
38	3x51	lpl_on	0	50	3	4	8
39	4x42	lpl_on	0	0	2	4	7
40	5x51	lpl_on	0	0	2	4	5
41	5x62	lpl_on	0	0	1	5	6
42	6x28	lpl_on	0	0	1	4	5
43	6x45	lpl_on	0	0	2	4	6
44	6x59	lpl_on	0	0	3	4	4
45	7x39	lpl_on	0	0	1	4	5
46	7x53	lpl_on	50	83.3333	3	6	9

Orange: nodes, hubs and links specific of lpl_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of lpl_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	lpl_off Recurrence	lpl_on Recurrence	lpl_off Hub1?	lpl_on Hub1?	lpl_off Hub2?	lpl_on Hub2?	ConSurf1	ConSurf2
1	2x57	2x60	lpl_off	19.9446	0	Yes	Yes	No	No	6	5
2	2x60	Lig	lpl_off	19.9399	1.95223	No	No	Yes	Yes	5	0
3	2x57	3x32	lpl_off	19.2268	0	Yes	Yes	No	No	6	6
4	3x32	Lig	lpl_off	21.4413	0	No	No	Yes	Yes	6	0
5	1x43	2x57	lpl_off	18.7623	9.94987	No	No	Yes	Yes	5	6
6	1x43	2x58	lpl_off	16.4493	8.83515	No	No	No	No	5	6
7	2x46	7x49	lpl_off	84.841	0	Yes	Yes	No	No	9	9
8	3x43	6x44	lpl_off	100	0	No	No	Yes	Yes	9	9
9	6x44	6x48	lpl_off	97.4102	5.11059	Yes	Yes	Yes	Yes	9	8
10	6x48	Lig	lpl_off	86.9053	0	Yes	Yes	Yes	Yes	8	0
11	8x50	8x54	lpl_off	18.2368	7.30758	Yes	No	Yes	Yes	8	7
12	8x47	8x50	lpl_off	58.9847	0	No	No	Yes	No	8	8
13	6x36	8x47	lpl_off	66.0927	0	No	No	No	No	9	8
14	6x36	7x56	lpl_off	67.0217	1.05868	No	No	No	No	9	7
15	6x39	7x56	lpl_off	68.6216	0	No	No	No	No	6	7
16	6x39	7x52	lpl_off	70.9487	4.88646	No	No	No	No	6	8
17	6x40	7x52	lpl_off	71.704	0	No	No	No	No	8	8
18	6x40	7x49	lpl_off	72.45	0	No	No	No	No	8	9
19	2x39	3x49	lpl_off	23.3086	1.734	No	No	Yes	No	8	9
20	2x39	2x43	lpl_off	39.2137	0	No	No	No	No	8	8
21	2x43	7x53	lpl_off	40.3256	0.905338	No	No	No	Yes	8	9
22	7x53	8x50	lpl_off	42.4041	0	No	Yes	Yes	No	9	8
23	5x43	Lig	lpl_off	11.3259	3.24683	Yes	No	Yes	Yes	6	0
24	3x40	5x47	lpl_off	13.0008	2.43881	No	No	Yes	Yes	7	7
25	3x43	6x41	lpl_off	29.3985	0	No	No	Yes	No	9	7
26	5x58	6x41	lpl_off	19.2503	3.99587	Yes	Yes	Yes	No	9	7
27	3x47	5x58	lpl_off	13.1181	0.931879	No	No	Yes	Yes	8	9
28	2x39	3x50	lpl_off	14.9855	0	No	No	Yes	No	8	9
29	3x47	5x57	lpl_off	11.8467	0	No	No	No	No	8	7
30	2x38	I2x53	lpl_off	10.9881	0	No	No	No	No	7	7
31	2x38	3x49	lpl_off	14.6711	0	No	No	Yes	No	7	9
32	4x59	5x39	lpl_off	15.525	0	Yes	No	Yes	No	5	7
33	6x48	6x52	lpl_off	11.4338	0	Yes	Yes	Yes	Yes	8	6
34	6x54	E2	lpl_off	10.4814	2.79269	No	No	Yes	Yes	4	4
35	1x40	2x58	lpl_off	14.1269	5.74757	Yes	Yes	No	No	3	6
36	3x50	6x30	lpl_off	11.218	0	Yes	No	No	No	9	7
37	4x55	4x59	lpl_off	12.9586	2.36213	No	No	Yes	No	4	5
38	Lig	NT	Shared	19.5177	12.2589	Yes	Yes	Yes	Yes	0	6
39	1x50	2x50	Shared	14.9104	15.3318	Yes	Yes	No	Yes	9	9
40	2x50	7x49	Shared	23.8106	44.7036	No	Yes	No	No	9	9
41	2x46	3x43	Shared	93.394	31.6072	Yes	Yes	No	No	9	9
42	2x45	3x42	Shared	12.0062	14.3999	No	No	No	No	9	8
43	2x46	3x42	Shared	19.7757	21.9552	Yes	Yes	No	No	9	8
44	2x57	7x42	Shared	11.7951	13.7157	Yes	Yes	No	No	6	7
45	3x40	5x50	Shared	10.8567	41.501	No	No	No	No	7	8
46	3x51	5x57	Shared	10.7253	34.6063	No	Yes	No	No	8	7
47	E2	Lig	Shared	34.8926	18.499	Yes	Yes	Yes	Yes	4	0
48	7x45	7x49	lpl_on	0	100	Yes	Yes	No	No	9	9
49	6x48	7x45	lpl_on	3.72525	93.2822	Yes	Yes	Yes	Yes	8	9
50	3x36	6x48	lpl_on	7.90091	78.0832	No	No	Yes	Yes	6	8
51	3x36	Lig	lpl_on	0	63.2203	No	No	Yes	Yes	6	0
52	2x40	I1x51	lpl_on	0	36.0041	No	Yes	No	No	9	7
53	2x41	I1x51	lpl_on	2.79159	39.2008	No	No	No	No	4	7
54	2x41	4x42	lpl_on	5.54096	42.3946	No	No	No	Yes	4	7
55	2x42	4x42	lpl_on	6.6529	59.1153	No	Yes	No	Yes	8	7
56	2x42	3x46	lpl_on	0	73.1495	No	Yes	No	Yes	8	8
57	2x46	3x46	lpl_on	0	51.5335	Yes	Yes	No	Yes	9	8
58	2x46	2x50	lpl_on	0	37.685	Yes	Yes	No	Yes	9	9
59	3x43	7x49	lpl_on	0	57.1336	No	No	No	No	9	9
60	3x46	7x53	lpl_on	0	23.9251	No	Yes	No	Yes	8	9
61	3x43	7x53	lpl_on	0	27.8443	No	No	No	Yes	9	9
62	2x40	I1x50	lpl_on	0.806981	22.1557	No	Yes	No	Yes	9	8
63	2x38	4x42	lpl_on	0	15.4733	No	No	No	Yes	7	7
64	2x42	3x49	lpl_on	9.22398	11.6072	No	Yes	Yes	No	8	9
65	2x45	4x50	lpl_on	9.60871	11.8343	No	No	Yes	Yes	9	9
66	3x36	7x42	lpl_on	0	14.7744	No	No	No	No	6	7
67	3x40	6x48	lpl_on	0	40.0206	No	No	Yes	Yes	7	8
68	3x44	5x50	lpl_on	0	39.5606	No	Yes	No	No	7	8
69	3x44	3x48	lpl_on	4.17566	36.6057	No	Yes	No	No	7	6
70	3x48	5x57	lpl_on	0	35.609	No	No	No	No	6	7
71	3x51	5x61	lpl_on	4.17566	23.8927	No	Yes	No	No	8	9
72	3x54	5x61	lpl_on	2.7869	22.8222	No	No	No	No	8	9
73	3x56	I2x56	lpl_on	0	10.8257	No	No	No	No	6	7
74	2x38	I2x56	lpl_on	0	12.0849	No	No	No	No	7	7
75	5x62	6x33	lpl_on	0	14.3704	No	Yes	No	No	6	8
76	5x65	6x33	lpl_on	0	15.2315	No	No	No	No	8	8
77	3x54	5x65	lpl_on	1.39345	21.7193	No	No	No	No	8	8

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
NT	NT	Shared	82.4837	66.282	1	1	1	1
E2	NT	Shared	91.1175	69.3038	1	1	1	1
3x21	NT	lpl_off	6.59625	0	1	0	2	1
3x22	NT	Shared	3.92625	4.17615	0	0	2	1
E1x501	NT	Shared	18.3587	8.56271	0	0	2	1
3x25	NT	Shared	12.6562	5.30922	1	1	2	1
E1x50	NT	Shared	6.02625	4.81469	1	1	2	1
Lig	NT	Shared	9.795	9.90135	1	1	0	1
E3	NT	Shared	7.425	3.59286	1	1	2	1
1x31	NT	Shared	4.90625	1.8475	0	0	2	1
2x57	2x60	lpl_off	4.515	0	0	0	2	1
2x57	3x32	lpl_off	4.5075	0	0	0	2	1
2x57	7x42	Shared	17.3875	14.2749	0	0	2	2
2x60	3x28	Shared	6.19625	6.30984	1	1	1	1
2x60	Lig	Shared	5.75375	6.10005	1	1	1	0
2x63	E1x52	lpl_off	8.095	0	0	0	2	2
3x28	E1x50	Shared	4.0425	3.7051	1	1	1	2
3x28	E1x52	Shared	4.86	3.33927	1	1	1	2
3x25	3x28	Shared	10.5	6.3125	1	1	2	1
3x25	3x29	Shared	9.70125	14.4405	1	1	2	1
3x25	E2	Shared	28.2062	19.0695	1	1	2	1
3x26	E2	Shared	13.6975	9.48661	1	1	2	1
3x28	3x29	Shared	8.73	5.36693	1	1	1	1
3x28	Lig	Shared	4.91875	4.02234	1	1	1	0
3x29	E2	Shared	7.7625	11.0469	1	1	1	1
3x29	Lig	Shared	15.5262	9.97729	1	1	1	0
3x32	Lig	lpl_off	9.045	0	0	0	1	0
3x33	E2	Shared	11.2313	5.71708	1	1	1	1
3x33	5x39	Shared	4.365	8.08948	1	1	1	2
3x33	5x43	lpl_off	4.6075	0	1	1	1	1
3x33	Lig	Shared	10.6388	8.1762	1	1	1	0
3x36	5x47	lpl_off	4.49375	0	0	0	1	2
3x36	6x48	Shared	13.665	6.31458	0	0	1	1
3x37	4x53	Shared	4.31	2.73938	0	1	1	2
3x37	4x56	Shared	4.70125	3.69234	0	1	1	2
3x40	5x47	Shared	6.335	3.62323	0	2	2	2
4x59	4x60	lpl_off	4.16	0	1	1	2	2
4x59	5x39	lpl_off	5.46625	0	1	1	2	2
4x60	E2	Shared	9.21375	10.2294	1	1	2	1
4x60	5x39	Shared	17.385	15.9081	1	1	2	2
5x36	E2	Shared	12.6613	4.43521	1	1	2	1
5x38	E2	Shared	4.92	7.41896	1	1	2	1
5x39	E2	Shared	17.9825	9.47208	1	1	2	1
5x42	E2	lpl_off	7.3925	0	1	0	2	1
E2	E2	Shared	41.74	42.9982	1	1	1	1
5x40	E2	lpl_off	7.01125	0	1	0	2	1
6x58	E2	Shared	18.4288	19.1585	1	1	2	1
6x54	E2	Shared	4.1025	3.07318	1	1	2	1
7x34	E2	Shared	5.24875	7.15849	1	1	1	1
E2	Lig	Shared	4.2875	5.48828	1	1	1	0
5x36	5x38	Shared	7.22	4.5425	1	1	2	2
5x39	5x43	lpl_off	8.5625	0	1	1	2	1
5x40	6x55	Shared	5.81875	4.3812	1	0	2	1
5x43	5x47	lpl_off	4.36125	0	1	1	1	2
5x43	Lig	Shared	3.85	7.26635	1	1	1	0
5x47	6x52	Shared	5.235	12.6552	0	2	2	2
6x44	6x48	Shared	15.6588	11.2019	1	2	2	1
6x44	7x45	Shared	6.64625	3.64958	1	2	2	2
6x48	6x52	lpl_off	4.5075	0	1	2	1	2
6x48	7x41	Shared	9.3975	3.78297	1	2	1	2
6x48	7x45	Shared	3.81375	10.2583	1	2	1	2
6x48	Lig	lpl_off	4.025	0	1	2	1	0
6x55	Lig	Shared	6.26	3.90354	0	0	1	0
6x58	7x31	Shared	8.14125	3.42828	1	1	2	2
E3	E3	Shared	5.24	4.23906	1	1	2	2
7x35	Lig	Shared	5.0425	4.595	0	0	1	0
7x38	Lig	Shared	16.875	10.508	0	0	1	0
7x34	NT	Shared	4.005	3.0375	1	1	1	1
E1x48	NT	Shared	8.615	6.21	1	1	2	1
7x34	Lig	Shared	8.0225	7.61828	1	1	1	0
6x51	Lig	Shared	3.5275	2.93427	0	0	1	0
1x32	NT	Shared	3.19375	3.9075	1	0	2	1
3x37	5x47	lpl_off	3.1875	0	0	1	1	2
E1	Lig	Shared	3.09	3.4425	0	0	1	0
5x37	E2	lpl_off	2.5725	0	1	0	2	1
E1x49	NT	lpl_off	2.5425	0	1	0	2	1
1x33	NT	lpl_off	2.32	0	0	0	2	1
2x64	Lig	Shared	2.045	1.77276	0	0	1	0
2x56	3x32	lpl_off	2.0225	0	0	0	2	1
1x35	7x35	Shared	1.7075	4.42609	0	0	2	1
4x63	E2	Shared	1.4875	0.800521	0	1	2	1
3x30	E2	lpl_off	1.45	0	0	0	2	1
1x30	NT	Shared	0.5475	1.8275	0	0	2	1
2x57	7x38	lpl_on	0	8.1649	0	0	2	1
2x63	3x28	lpl_on	0	5.58625	0	0	2	1
3x25	3x26	lpl_on	0	3.49677	1	1	2	2
3x36	Lig	lpl_on	0	4.39344	0	0	1	0
3x37	Lig	lpl_on	0	3.06807	0	1	1	0
3x40	6x48	lpl_on	0	4.18719	0	2	2	1
4x56	5x43	lpl_on	0	3.20411	0	1	2	1
4x59	E2	lpl_on	0	4.15531	1	1	2	1
7x31	E2	lpl_on	0	3.65828	0	1	2	1
5x47	6x48	lpl_on	0	10.2707	0	2	2	1
2x60	3x32	lpl_on	0	4.01182	1	1	1	1
5x47	6x44	lpl_on	0	3.81339	0	2	2	2
3x36	7x42	lpl_on	0	3.51453	0	0	1	2
3x37	5x43	lpl_on	0	3.335	0	1	1	1
4x56	5x42	lpl_on	0	2.74568	0	1	2	2
3x30	3x33	lpl_on	0	2.7163	0	0	2	1
7x35	7x36	lpl_on	0	2.23385	0	0	1	2
3x33	4x57	lpl_on	0	1.4613	1	1	1	2
E1x48	E1x49	lpl_on	0	1.13958	1	1	2	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	lpl_off	s1p_off lpa_off
	lpl_on	s1p_on lpa_on

Network Difference
Value	lpl_off	lpl_on
I_min	3.81125	2.9949
Number of Linked Nodes	253	261
Number of Specific Nodes	4 (1.58%)	12 (4.60%)
Number of Shared Nodes	249 (98.42%)	249 (95.40%)
Number of Links	280	292
Number of Specific Links	111 (39.64%)	123 (42.12%)
Number of Shared Links	169 (60.36%)	169 (57.88%)
Number of Hubs	29	37
Number of Specific Hubs	9 (31.03%)	17 (45.95%)
Number of Shared Hubs	20 (68.97%)	20 (54.05%)
Average % Shared Neighbours (Jaccard)	44.83
Average % Shared Neighbours (Otsuka)	53.40
Average % Shared Neighbours (Overlap Coefficient)	62.23
Average % Shared Cliques (k3-6)	88.89
Graphlets Similarity	0.704456

Paths Difference
Value	lpl_off	lpl_on
Number Of Nodes in MetaPath	49	39
Specific Nodes in MetaPath	29 (59.18%)	19 (48.72%)
Shared Nodes in MetaPath	249 (98.42%)	249 (98.42%)
Number Of Links MetaPath	47	40
Specific Links in MetaPath	37 (78.72%)	30 (75.00%)
Shared Links in MetaPath	169 (60.36%)	169 (60.36%)
Number of Shortest Paths	40313	54617
Length Of Smallest Path	3	3
Average Path Length	13.0107	13.7037
Length of Longest Path	30	32
Minimum Path Strength	0.18125	0.180469
Average Path Strength	6.10986	5.38862
Maximum Path Strength	54.55	39.7666
Minimum Path Correlation	0.70125	0.705
Average Path Correlation	0.903383	0.901729
Maximum Path Correlation	0.99	0.99
Minimum % Of Corr. Nodes	3.7037	3.44828
Average % Of Corr. Nodes	45.2089	43.8607
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	39.0088	46.1537
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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