psnGPCR

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Orange: nodes, hubs and links specific of mop_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of mop_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	mop_off Int. Strength	mop_on Int. Strength	mop_off Hub1?	mop_on Hub1?	mop_off Hub2?	mop_on Hub2?	ConSurf1	ConSurf2
1	1x35	1x39	mop_off	100	0	No	No	No	Yes	4	7
2	1x39	7x42	mop_off	100	0	No	Yes	Yes	Yes	7	7
3	1x48	1x49	mop_off	100	0	No	No	No	No	4	7
4	1x50	2x47	mop_off	100	0	Yes	No	No	No	9	9
5	1x52	8x54	mop_off	100	0	No	No	No	No	6	6
6	1x52	8x57	mop_off	100	0	No	No	No	No	6	5
7	1x53	7x53	mop_off	100	0	No	Yes	Yes	Yes	9	9
8	1x55	8x57	mop_off	100	0	No	No	No	No	4	5
9	1x56	8x53	mop_off	100	0	No	No	No	No	7	5
10	1x60	8x53	mop_off	100	0	Yes	No	No	No	5	5
11	2x40	I1x50	mop_off	100	0	No	No	No	No	8	7
12	8x50	I1x50	mop_off	100	0	Yes	Yes	No	No	9	7
13	2x41	4x42	mop_off	100	0	No	No	No	No	6	7
14	2x42	4x45	mop_off	100	0	Yes	Yes	No	No	7	5
15	2x43	7x53	mop_off	100	0	No	No	Yes	Yes	8	9
16	2x45	3x42	mop_off	100	0	No	No	No	No	9	7
17	2x46	7x53	mop_off	100	0	No	No	Yes	Yes	9	9
18	2x56	3x28	mop_off	100	0	No	No	No	No	6	5
19	3x30	3x34	mop_off	100	0	No	No	Yes	Yes	6	4
20	3x35	3x39	mop_off	100	0	No	No	No	No	8	9
21	3x36	6x52	mop_off	100	0	No	No	No	Yes	7	8
22	3x38	4x49	mop_off	100	0	No	Yes	No	No	7	7
23	3x39	6x44	mop_off	100	0	No	No	Yes	No	9	9
24	3x40	3x41	mop_off	100	0	No	No	No	No	8	6
25	3x40	6x44	mop_off	100	0	No	No	Yes	No	8	9
26	3x41	4x49	mop_off	100	0	No	No	No	No	6	7
27	3x42	4x49	mop_off	100	0	No	No	No	No	7	7
28	3x43	6x41	mop_off	100	0	No	No	No	No	8	8
29	3x43	6x44	mop_off	100	0	No	No	Yes	No	8	9
30	3x46	6x37	mop_off	100	0	No	No	No	No	8	7
31	3x50	6x33	mop_off	100	0	No	No	No	No	9	7
32	3x50	6x34	mop_off	100	0	No	No	No	No	9	6
33	3x50	6x37	mop_off	100	0	No	No	No	No	9	7
34	3x56	I2x52	mop_off	100	0	No	No	No	No	6	4
35	4x38	4x40	mop_off	100	0	No	No	No	No	7	3
36	E2x52	Lig	mop_off	100	0	No	No	Yes	Yes	5	0
37	5x40	6x55	mop_off	100	0	No	No	No	No	4	5
38	5x54	6x41	mop_off	100	0	No	No	No	No	8	8
39	5x58	5x61	mop_off	100	0	Yes	Yes	No	No	9	8
40	5x58	6x38	mop_off	100	0	Yes	Yes	No	No	9	4
41	5x64	5x68	mop_off	100	0	No	No	No	No	5	6
42	6x31	I3	mop_off	100	0	No	No	Yes	Yes	5	4
43	6x27	6x31	mop_off	100	0	No	No	No	No	3	5
44	6x28	6x32	mop_off	100	0	No	No	Yes	No	4	7
45	6x36	8x47	mop_off	100	0	No	No	No	No	8	8
46	6x39	7x56	mop_off	100	0	No	No	No	No	6	6
47	6x40	7x49	mop_off	100	0	No	No	Yes	Yes	8	9
48	6x54	7x37	mop_off	100	0	No	No	No	No	4	6
49	6x58	7x30	mop_off	100	0	No	No	No	No	4	4
50	E3	E3	mop_off	100	0	Yes	No	Yes	No	2	2
51	1x42	7x47	mop_off	100	0	Yes	No	No	No	7	7
52	3x54	6x30	mop_off	100	0	No	No	No	No	8	6
53	5x36	Lig	mop_off	100	0	No	No	Yes	Yes	4	0
54	5x40	Lig	mop_off	100	0	No	No	Yes	Yes	4	0
55	6x27	6x29	mop_off	100	0	No	No	No	No	3	5
56	E2	Lig	mop_off	100	0	Yes	Yes	Yes	Yes	4	0
57	E3	Lig	mop_off	100	0	Yes	No	Yes	Yes	2	0
58	8x53	I1x50	mop_off	66.6667	0	No	No	No	No	5	7
59	2x37	2x39	mop_off	33.3333	0	No	No	No	No	8	8
60	3x33	5x39	mop_off	33.3333	0	No	No	No	No	4	5
61	7x29	7x33	mop_off	66.6667	0	No	No	No	No	2	5
62	2x39	6x33	mop_off	66.6667	0	No	No	No	No	8	7
63	5x33	5x37	mop_off	33.3333	0	No	No	No	No	2	3
64	I1x48	I1x51	mop_off	33.3333	0	No	No	No	No	6	6
65	1x60	8x56	mop_off	66.6667	0	Yes	No	No	No	5	4
66	6x43	7x45	mop_off	33.3333	0	No	No	Yes	Yes	6	9
67	3x51	5x61	mop_off	33.3333	0	Yes	Yes	No	No	8	8
68	E1x50	E2	mop_off	33.3333	0	Yes	Yes	Yes	Yes	8	4
69	2x38	I2x57	mop_off	33.3333	0	No	No	Yes	Yes	6	6
70	3x26	4x64	mop_off	0	0	No	No	No	No	6	4
71	5x45	5x48	mop_off	33.3333	0	No	No	No	No	4	5
72	6x57	6x61	mop_off	0	0	No	No	No	No	5	3
73	2x60	3x28	mop_off	33.3333	0	No	No	No	No	6	5
74	7x54	8x54	mop_off	33.3333	0	No	No	No	No	7	6
75	7x45	7x48	mop_off	33.3333	0	Yes	Yes	No	No	9	7
76	8x58	8x59	mop_off	33.3333	0	No	No	No	No	5	2
77	6x47	7x40	mop_off	33.3333	0	No	No	No	No	8	7
78	2x49	3x35	mop_off	0	0	No	No	No	No	8	8
79	1x60	I1x48	mop_off	33.3333	0	Yes	No	No	No	5	6
80	7x55	7x56	mop_off	33.3333	0	No	Yes	No	No	6	6
81	1x38	1x42	mop_off	33.3333	0	No	No	Yes	No	5	7
82	5x63	5x66	mop_off	33.3333	0	No	No	No	No	2	4
83	7x31	E3	mop_off	0	0	No	No	Yes	No	4	2
84	2x48	2x52	mop_off	0	0	No	No	No	No	6	7
85	I2x54	I2x55	mop_off	33.3333	0	No	No	No	No	5	4
86	3x48	5x57	mop_off	0	0	No	No	No	No	6	7
87	4x59	4x63	mop_off	0	0	No	No	No	No	7	4
88	4x39	I1x51	mop_off	33.3333	0	No	No	No	No	1	6
89	7x28	7x31	mop_off	0	0	No	No	No	No	4	4
90	5x37	6x59	mop_off	0	0	No	No	No	No	3	4
91	3x55	I2x50	mop_off	33.3333	0	No	No	No	No	7	7
92	4x61	4x62	mop_off	33.3333	0	No	No	No	No	4	5
93	2x67	E1x49	mop_off	0	0	No	No	No	No	4	5
94	2x58	2x61	mop_off	0	0	No	No	No	No	8	6
95	1x29	1x32	mop_off	0	0	No	No	No	No	2	4
96	1x44	1x45	mop_off	0	0	No	No	No	No	5	5
97	7x31	7x32	mop_off	0	0	No	No	No	No	4	1
98	1x30	1x33	mop_off	0	0	No	No	No	No	2	4
99	1x33	1x36	mop_off	0	0	No	No	Yes	No	4	5
100	6x24	6x26	mop_off	0	0	No	No	No	No	1	4
101	4x41	4x44	mop_off	0	0	No	Yes	No	No	4	3
102	I2x55	I2x56	mop_off	0	0	No	No	No	Yes	4	4
103	I2x50	I2x51	mop_off	0	0	No	No	No	No	7	5
104	2x55	2x56	mop_off	0	0	No	No	No	No	5	6
105	2x54	2x55	mop_off	0	0	No	No	No	No	6	5
106	5x66	5x67	mop_off	0	0	No	No	No	No	4	4
107	5x67	I3	mop_off	0	0	No	No	Yes	Yes	4	4
108	5x58	5x59	mop_off	0	0	Yes	Yes	No	No	9	2
109	8x55	8x58	mop_off	0	0	No	No	No	No	5	5
110	1x35	2x64	Shared	100	100	No	No	No	Yes	4	5
111	1x36	2x65	Shared	100	100	Yes	No	No	No	5	5
112	1x39	2x57	Shared	100	100	No	Yes	Yes	Yes	7	7
113	1x47	2x54	Shared	100	100	No	No	No	No	6	6
114	1x50	2x50	Shared	100	100	Yes	No	No	Yes	9	9
115	1x50	7x50	Shared	100	100	Yes	No	No	No	9	9
116	1x54	2x44	Shared	100	100	No	No	No	Yes	7	6
117	1x55	1x59	Shared	100	100	No	No	No	No	4	4
118	1x57	2x44	Shared	100	100	No	No	No	Yes	7	6
119	1x57	8x50	Shared	100	100	No	No	Yes	Yes	7	9
120	1x59	1x60	Shared	100	100	No	No	Yes	No	4	5
121	2x37	2x40	Shared	100	100	No	No	No	No	8	8
122	2x40	8x50	Shared	100	100	No	No	Yes	Yes	8	9
123	2x41	4x46	Shared	100	12.5	No	No	No	No	6	7
124	2x42	3x45	Shared	100	100	Yes	Yes	No	No	7	7
125	2x42	3x46	Shared	100	100	Yes	Yes	No	No	7	8
126	2x42	3x49	Shared	100	100	Yes	Yes	No	No	7	8
127	2x42	4x42	Shared	100	100	Yes	Yes	No	No	7	7
128	2x45	4x46	Shared	100	100	No	No	No	No	9	7
129	2x45	4x50	Shared	100	100	No	No	Yes	Yes	9	9
130	2x50	7x46	Shared	100	100	No	Yes	No	No	9	9
131	2x50	7x49	Shared	100	100	No	Yes	Yes	Yes	9	9
132	2x53	3x35	Shared	100	12.5	No	No	No	No	7	8
133	2x56	3x31	Shared	100	25	No	No	No	No	6	5
134	2x57	7x42	Shared	100	100	Yes	Yes	Yes	Yes	7	7
135	2x59	E1x52	Shared	100	100	No	No	Yes	Yes	6	7
136	2x60	7x42	Shared	100	100	No	No	Yes	Yes	6	7
137	2x60	Lig	Shared	100	100	No	No	Yes	Yes	6	0
138	2x62	E1x52	Shared	100	100	No	No	Yes	Yes	5	7
139	2x63	E1x50	Shared	100	100	No	No	Yes	Yes	6	8
140	2x64	7x35	Shared	100	100	No	Yes	No	Yes	5	4
141	2x66	E1x51	Shared	100	50	No	No	No	No	3	4
142	E1x49	E2	Shared	100	100	No	No	Yes	Yes	5	4
143	E1x50	E1x52	Shared	100	100	Yes	Yes	Yes	Yes	8	7
144	3x25	E1x50	Shared	100	100	No	No	Yes	Yes	9	8
145	E1x50	E2x50	Shared	100	100	Yes	Yes	No	No	8	9
146	E1x51	E1x52	Shared	100	100	No	No	Yes	Yes	4	7
147	3x24	E1x52	Shared	100	100	No	No	Yes	Yes	6	7
148	3x22	3x26	Shared	100	12.5	No	No	No	No	1	6
149	3x22	E2	Shared	100	100	No	No	Yes	Yes	1	4
150	3x25	E2x50	Shared	100	100	No	No	No	No	9	9
151	3x30	4x61	Shared	100	100	No	No	No	No	6	4
152	3x32	7x42	Shared	100	100	No	Yes	Yes	Yes	6	7
153	3x32	Lig	Shared	100	100	No	Yes	Yes	Yes	6	0
154	3x33	4x60	Shared	100	100	No	No	No	No	4	5
155	3x33	Lig	Shared	100	100	No	No	Yes	Yes	4	0
156	3x34	4x50	Shared	100	100	Yes	Yes	Yes	Yes	4	9
157	3x34	4x54	Shared	100	0	Yes	Yes	No	No	4	3
158	3x34	4x57	Shared	100	25	Yes	Yes	No	No	4	7
159	3x36	6x48	Shared	100	100	No	No	Yes	Yes	7	8
160	3x36	Lig	Shared	100	100	No	No	Yes	Yes	7	0
161	3x37	4x56	Shared	100	100	No	Yes	No	No	7	4
162	3x37	5x43	Shared	100	100	No	Yes	No	No	7	5
163	3x37	5x461	Shared	100	50	No	Yes	No	No	7	6
164	3x38	4x50	Shared	100	100	No	Yes	Yes	Yes	7	9
165	3x38	4x53	Shared	100	100	No	Yes	No	No	7	8
166	3x40	5x50	Shared	100	50	No	No	No	No	8	9
167	3x44	5x53	Shared	100	25	No	No	No	No	7	7
168	3x47	5x54	Shared	100	100	No	No	No	No	9	8
169	3x47	5x58	Shared	100	100	No	No	Yes	Yes	9	9
170	3x49	I2x57	Shared	100	100	No	No	Yes	Yes	8	6
171	3x51	3x55	Shared	100	100	Yes	Yes	No	No	8	7
172	3x51	3x56	Shared	100	100	Yes	Yes	No	No	8	6
173	3x51	5x60	Shared	100	100	Yes	Yes	No	No	8	4
174	3x53	I2x57	Shared	100	100	No	No	Yes	Yes	8	6
175	3x54	5x61	Shared	100	100	No	No	No	No	8	8
176	3x55	5x64	Shared	100	37.5	No	No	No	No	7	5
177	4x38	4x39	Shared	100	12.5	No	No	No	No	7	1
178	4x38	4x41	Shared	100	25	No	No	No	Yes	7	4
179	4x54	4x58	Shared	100	100	No	No	No	No	3	3
180	E2	E2	Shared	100	100	Yes	Yes	Yes	Yes	4	4
181	E2	E2x51	Shared	100	100	Yes	Yes	No	No	4	3
182	E2	E2x52	Shared	100	100	Yes	Yes	No	No	4	5
183	5x35	E2	Shared	100	100	No	No	Yes	Yes	3	4
184	5x36	E2	Shared	100	100	No	No	Yes	Yes	4	4
185	5x34	5x35	Shared	100	100	No	No	No	No	3	3
186	5x43	Lig	Shared	100	100	No	No	Yes	Yes	5	0
187	5x44	5x48	Shared	100	100	No	Yes	No	No	5	5
188	5x44	6x56	Shared	100	100	No	Yes	No	No	5	6
189	5x45	5x46	Shared	100	50	No	No	No	No	4	4
190	5x47	6x49	Shared	100	100	Yes	Yes	Yes	Yes	8	5
191	5x47	6x52	Shared	100	100	Yes	Yes	No	Yes	8	8
192	5x54	5x58	Shared	100	100	No	No	Yes	Yes	8	9
193	6x27	I3	Shared	100	37.5	No	No	Yes	Yes	3	4
194	6x32	8x48	Shared	100	100	Yes	No	No	No	7	4
195	6x36	7x56	Shared	100	100	No	No	No	No	8	6
196	6x40	7x53	Shared	100	100	No	No	Yes	Yes	8	9
197	6x44	6x48	Shared	100	100	Yes	No	Yes	Yes	9	8
198	6x44	7x45	Shared	100	100	Yes	No	Yes	Yes	9	9
199	6x47	7x45	Shared	100	100	No	No	Yes	Yes	8	9
200	6x48	7x45	Shared	100	100	Yes	Yes	Yes	Yes	8	9
201	6x51	Lig	Shared	100	100	No	No	Yes	Yes	6	0
202	6x52	Lig	Shared	100	100	No	Yes	Yes	Yes	8	0
203	6x54	7x34	Shared	100	100	No	No	Yes	Yes	4	5
204	6x55	Lig	Shared	100	100	No	No	Yes	Yes	5	0
205	6x58	7x34	Shared	100	100	No	No	Yes	Yes	4	5
206	7x30	E3	Shared	100	100	No	No	Yes	No	4	2
207	7x34	7x35	Shared	100	100	Yes	Yes	No	Yes	5	4
208	7x34	7x38	Shared	100	100	Yes	Yes	No	No	5	5
209	7x34	Lig	Shared	100	100	Yes	Yes	Yes	Yes	5	0
210	7x38	Lig	Shared	100	100	No	No	Yes	Yes	5	0
211	7x42	Lig	Shared	100	100	Yes	Yes	Yes	Yes	7	0
212	7x49	7x53	Shared	100	100	Yes	Yes	Yes	Yes	9	9
213	8x47	8x50	Shared	100	100	No	No	Yes	Yes	8	9
214	8x49	8x52	Shared	100	37.5	No	No	No	No	6	4
215	8x51	8x55	Shared	100	12.5	No	No	No	No	8	5
216	5x36	5x40	Shared	100	100	No	No	No	No	4	4
217	6x54	7x33	Shared	100	100	No	No	No	No	4	5
218	7x45	7x49	Shared	100	100	Yes	Yes	Yes	Yes	9	9
219	8x48	8x51	Shared	100	100	No	No	No	No	4	8
220	1x60	8x57	Shared	100	100	Yes	No	No	No	5	5
221	Lig	Lig	Shared	100	100	Yes	Yes	Yes	Yes	0	0
222	6x48	7x41	Shared	33.3333	37.5	Yes	Yes	No	No	8	7
223	3x29	E2x50	Shared	33.3333	100	No	No	No	No	5	9
224	3x41	4x52	Shared	66.6667	12.5	No	No	No	No	6	4
225	5x44	5x47	Shared	66.6667	100	No	Yes	Yes	Yes	5	8
226	1x42	7x43	Shared	33.3333	0	Yes	No	No	No	7	5
227	5x31	5x33	Shared	33.3333	100	No	No	No	No	0	2
228	3x44	5x50	Shared	66.6667	100	No	No	No	No	7	9
229	3x51	5x57	Shared	66.6667	100	Yes	Yes	No	No	8	7
230	6x23	6x26	Shared	33.3333	100	No	No	No	No	4	4
231	1x58	2x44	Shared	66.6667	25	No	No	No	Yes	3	6
232	6x45	6x49	Shared	33.3333	37.5	No	No	Yes	Yes	5	5
233	6x43	7x52	Shared	33.3333	100	No	No	No	Yes	6	8
234	3x54	5x65	Shared	66.6667	100	No	No	No	No	8	8
235	6x49	6x50	Shared	66.6667	50	Yes	Yes	No	No	5	9
236	5x42	5x46	Shared	33.3333	37.5	No	No	No	No	3	4
237	1x49	7x50	Shared	66.6667	37.5	No	No	No	No	7	9
238	8x47	8x49	Shared	33.3333	25	No	No	No	No	8	6
239	2x48	4x50	Shared	33.3333	100	No	No	Yes	Yes	6	9
240	1x43	2x57	Shared	33.3333	100	No	No	Yes	Yes	6	7
241	4x63	E2	Shared	33.3333	100	No	No	Yes	Yes	4	4
242	6x26	I3	Shared	33.3333	12.5	No	No	Yes	Yes	4	4
243	1x43	2x58	Shared	66.6667	100	No	No	No	No	6	8
244	1x42	2x57	Shared	33.3333	0	Yes	No	Yes	Yes	7	7
245	2x41	4x43	Shared	0	25	No	No	No	No	6	2
246	6x29	6x32	Shared	33.3333	100	No	No	Yes	No	5	7
247	I1x49	I1x51	Shared	33.3333	0	No	No	No	No	5	6
248	5x48	5x52	Shared	0	0	No	No	No	No	5	3
249	7x27	7x30	Shared	33.3333	0	No	No	No	No	1	4
250	5x34	5x38	Shared	33.3333	100	No	No	No	No	3	4
251	1x45	7x47	Shared	66.6667	50	No	No	No	No	5	7
252	5x33	5x34	Shared	33.3333	100	No	No	No	No	2	3
253	5x49	5x50	Shared	0	25	No	No	No	No	5	9
254	5x32	E2	Shared	33.3333	25	No	No	Yes	Yes	3	4
255	5x47	5x51	Shared	33.3333	37.5	Yes	Yes	No	No	8	6
256	5x65	I3	Shared	33.3333	100	No	No	Yes	Yes	8	4
257	3x52	I2x56	Shared	33.3333	100	No	No	No	Yes	5	4
258	1x50	2x51	Shared	0	100	Yes	No	No	No	9	7
259	3x48	3x52	Shared	33.3333	0	No	No	No	No	6	5
260	4x47	4x51	Shared	33.3333	0	No	No	No	No	4	4
261	1x47	1x51	Shared	33.3333	100	No	No	No	No	6	4
262	7x36	7x40	Shared	33.3333	37.5	No	No	No	No	5	7
263	1x31	1x35	Shared	33.3333	0	No	No	No	No	3	4
264	1x46	7x47	Shared	0	100	No	No	No	No	8	7
265	3x23	3x27	Shared	0	0	No	No	No	No	2	5
266	3x27	3x31	Shared	0	12.5	No	No	No	No	5	5
267	6x23	6x25	Shared	33.3333	0	No	No	No	No	4	2
268	6x60	6x61	Shared	0	0	No	No	No	No	5	3
269	5x60	5x63	Shared	0	0	No	No	No	No	4	2
270	1x46	2x54	Shared	0	12.5	No	No	No	No	8	6
271	6x32	6x35	Shared	33.3333	12.5	Yes	No	No	No	7	6
272	1x32	2x64	Shared	33.3333	12.5	No	No	No	Yes	4	5
273	1x30	1x34	Shared	0	0	No	No	No	No	2	4
274	5x51	5x55	Shared	0	0	No	No	No	No	6	4
275	1x36	2x61	Shared	33.3333	100	Yes	No	No	No	5	6
276	6x49	6x53	Shared	0	0	Yes	Yes	No	No	5	6
277	5x56	5x60	Shared	0	0	No	No	No	No	4	4
278	6x53	6x57	Shared	0	12.5	No	No	No	No	6	5
279	3x21	E1x50	Shared	0	0	No	No	Yes	Yes	7	8
280	I2x53	I2x57	Shared	0	0	No	No	Yes	Yes	6	6
281	4x44	4x48	Shared	0	0	No	No	No	No	3	4
282	1x38	7x39	Shared	0	100	No	No	No	No	5	4
283	1x36	1x40	Shared	0	0	Yes	No	No	No	5	4
284	5x41	5x45	Shared	0	12.5	No	No	No	No	4	4
285	7x51	7x55	Shared	0	100	No	No	No	Yes	6	6
286	1x41	1x45	Shared	0	0	No	No	No	No	5	5
287	1x35	7x35	mop_on	0	100	No	No	No	Yes	4	4
288	1x39	7x35	mop_on	0	100	No	Yes	No	Yes	7	4
289	1x39	7x38	mop_on	0	100	No	Yes	No	No	7	5
290	1x53	7x54	mop_on	0	100	No	Yes	No	No	9	7
291	1x54	2x48	mop_on	0	100	No	No	No	No	7	6
292	2x40	I1x48	mop_on	0	100	No	No	No	No	8	6
293	2x44	I1x50	mop_on	0	100	No	Yes	No	No	6	7
294	2x39	I2x57	mop_on	0	100	No	No	Yes	Yes	8	6
295	2x42	4x46	mop_on	0	100	Yes	Yes	No	No	7	7
296	2x43	8x50	mop_on	0	100	No	No	Yes	Yes	8	9
297	2x46	2x50	mop_on	0	100	No	No	No	Yes	9	9
298	2x46	3x42	mop_on	0	100	No	No	No	No	9	7
299	2x46	3x43	mop_on	0	100	No	No	No	No	9	8
300	2x50	3x39	mop_on	0	100	No	Yes	No	No	9	9
301	2x52	3x35	mop_on	0	100	No	No	No	No	7	8
302	2x56	3x32	mop_on	0	100	No	No	No	Yes	6	6
303	2x59	3x28	mop_on	0	100	No	No	No	No	6	5
304	2x60	3x32	mop_on	0	100	No	No	No	Yes	6	6
305	2x63	Lig	mop_on	0	100	No	No	Yes	Yes	6	0
306	3x29	4x64	mop_on	0	100	No	No	No	No	5	4
307	3x29	Lig	mop_on	0	100	No	No	Yes	Yes	5	0
308	3x31	3x35	mop_on	0	100	No	No	No	No	5	8
309	3x34	3x38	mop_on	0	100	Yes	Yes	No	Yes	4	7
310	3x34	4x53	mop_on	0	100	Yes	Yes	No	No	4	8
311	3x37	3x41	mop_on	0	100	No	Yes	No	No	7	6
312	3x40	6x48	mop_on	0	100	No	No	Yes	Yes	8	8
313	3x43	7x49	mop_on	0	100	No	No	Yes	Yes	8	9
314	3x43	7x53	mop_on	0	100	No	No	Yes	Yes	8	9
315	3x45	4x49	mop_on	0	100	No	No	No	No	7	7
316	3x46	7x53	mop_on	0	100	No	No	Yes	Yes	8	9
317	3x47	5x57	mop_on	0	100	No	No	No	No	9	7
318	3x49	I2x56	mop_on	0	100	No	No	No	Yes	8	4
319	3x50	5x58	mop_on	0	100	No	No	Yes	Yes	9	9
320	3x50	7x53	mop_on	0	100	No	No	Yes	Yes	9	9
321	4x41	I2x56	mop_on	0	100	No	Yes	No	Yes	4	4
322	4x40	4x44	mop_on	0	100	No	No	No	No	3	3
323	4x41	4x45	mop_on	0	100	No	Yes	No	No	4	5
324	5x39	E2	mop_on	0	100	No	No	Yes	Yes	5	4
325	5x31	E2	mop_on	0	100	No	No	Yes	Yes	0	4
326	5x44	6x52	mop_on	0	100	No	Yes	No	Yes	5	8
327	5x47	5x48	mop_on	0	100	Yes	Yes	No	No	8	5
328	5x54	6x44	mop_on	0	100	No	No	Yes	No	8	9
329	5x58	6x37	mop_on	0	100	Yes	Yes	No	No	9	7
330	5x62	6x34	mop_on	0	100	No	No	No	No	5	6
331	5x62	6x37	mop_on	0	100	No	No	No	No	5	7
332	5x68	I3	mop_on	0	100	No	No	Yes	Yes	6	4
333	6x30	I3	mop_on	0	100	No	No	Yes	Yes	6	4
334	6x25	6x28	mop_on	0	100	No	No	No	No	2	4
335	6x40	7x52	mop_on	0	100	No	No	No	Yes	8	8
336	6x48	6x52	mop_on	0	100	Yes	Yes	No	Yes	8	8
337	6x51	7x37	mop_on	0	100	No	No	No	No	6	6
338	6x54	7x30	mop_on	0	100	No	No	No	No	4	4
339	1x39	2x61	mop_on	0	100	No	Yes	No	No	7	6
340	3x28	E1x50	mop_on	0	100	No	No	Yes	Yes	5	8
341	7x55	8x54	mop_on	0	100	No	Yes	No	No	6	6
342	5x40	6x59	mop_on	0	25	No	No	No	No	4	4
343	3x50	5x61	mop_on	0	50	No	No	No	No	9	8
344	1x53	2x47	mop_on	0	50	No	Yes	No	No	9	9
345	3x25	E2	mop_on	0	37.5	No	No	Yes	Yes	9	4
346	2x49	3x38	mop_on	0	37.5	No	No	No	Yes	8	7
347	1x43	1x47	mop_on	0	12.5	No	No	No	No	6	6
348	5x58	6x41	mop_on	0	50	Yes	Yes	No	No	9	8
349	2x64	7x31	mop_on	0	50	No	Yes	No	No	5	4
350	1x52	7x55	mop_on	0	50	No	No	No	Yes	6	6
351	8x56	8x57	mop_on	0	12.5	No	No	No	No	4	5
352	1x53	1x57	mop_on	0	12.5	No	Yes	No	No	9	7
353	6x50	7x40	mop_on	0	37.5	No	No	No	No	9	7
354	6x56	6x60	mop_on	0	0	No	No	No	No	6	5
355	6x29	6x33	mop_on	0	25	No	No	No	No	5	7
356	6x43	7x48	mop_on	0	37.5	No	No	No	No	6	7
357	1x53	7x55	mop_on	0	25	No	Yes	No	Yes	9	6
358	1x31	7x28	mop_on	0	25	No	No	No	No	3	4
359	5x64	5x67	mop_on	0	12.5	No	No	No	No	5	4
360	1x56	8x54	mop_on	0	37.5	No	No	No	No	7	6
361	1x48	1x52	mop_on	0	12.5	No	No	No	No	4	6
362	1x29	1x33	mop_on	0	25	No	No	No	No	2	4
363	5x62	5x66	mop_on	0	0	No	No	No	No	5	4
364	1x31	7x32	mop_on	0	12.5	No	No	No	No	3	1
365	5x38	5x42	mop_on	0	0	No	No	No	No	4	3
366	1x38	7x36	mop_on	0	25	No	No	No	No	5	5
367	4x58	4x59	mop_on	0	12.5	No	No	No	No	3	7
368	2x38	4x42	mop_on	0	0	No	No	No	No	6	7
369	I2x52	I2x56	mop_on	0	25	No	No	No	Yes	4	4
370	2x37	I1x51	mop_on	0	0	No	No	No	No	8	6
371	6x39	7x52	mop_on	0	0	No	No	No	Yes	6	8
372	6x34	6x38	mop_on	0	0	No	No	No	No	6	4
373	5x37	5x40	mop_on	0	12.5	No	No	No	No	3	4
374	3x56	I2x50	mop_on	0	0	No	No	No	No	6	7
375	2x52	2x55	mop_on	0	0	No	No	No	No	7	5
376	5x65	6x33	mop_on	0	0	No	No	No	No	8	7
377	3x30	4x57	mop_on	0	0	No	No	No	No	6	7
378	6x31	6x35	mop_on	0	12.5	No	No	No	No	5	6
379	2x66	2x67	mop_on	0	0	No	No	No	No	3	4
380	1x56	1x60	mop_on	0	12.5	No	No	Yes	No	7	5
381	4x40	4x41	mop_on	0	25	No	No	No	Yes	3	4
382	7x52	7x56	mop_on	0	0	No	Yes	No	No	8	6
383	7x27	7x29	mop_on	0	0	No	No	No	No	1	2
384	4x62	4x63	mop_on	0	12.5	No	No	No	No	5	4
385	Lig	NT	mop_on	0	12.5	Yes	Yes	No	No	0	0
386	8x53	I1x48	mop_on	0	0	No	No	No	No	5	6
387	1x29	NT	mop_on	0	0	No	No	No	No	2	0
388	1x29	1x30	mop_on	0	0	No	No	No	No	2	2
389	6x24	6x28	mop_on	0	0	No	No	No	No	1	4
390	I2x52	I2x55	mop_on	0	0	No	No	No	No	4	4

Orange: nodes, hubs and links specific of mop_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of mop_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	mop_off Avg Int. Strength	mop_on Avg Int. Strength	mop_off Num Of Links	mop_on Num Of Links	ConSurf
1	1x36	mop_off	0	0	4	3	5
2	1x42	mop_off	0	0	4	2	7
3	1x50	mop_off	0	25	4	3	9
4	1x60	mop_off	33.3333	0	5	3	5
5	6x32	mop_off	33.3333	0	4	3	7
6	6x44	mop_off	100	37.5	5	3	9
7	E3	mop_off	0	12.5	5	1	2
8	2x42	Shared	66.6667	87.5	5	5	7
9	2x57	Shared	0	0	4	4	7
10	E1x50	Shared	66.6667	100	6	6	8
11	E1x52	Shared	66.6667	87.5	5	5	7
12	3x34	Shared	66.6667	62.5	4	5	4
13	3x51	Shared	66.6667	75	5	4	8
14	I2x57	Shared	33.3333	0	4	4	6
15	4x50	Shared	66.6667	75	4	4	9
16	E2	Shared	100	100	12	13	4
17	5x47	Shared	66.6667	50	4	5	8
18	5x58	Shared	33.3333	75	5	5	9
19	I3	Shared	33.3333	62.5	5	5	4
20	6x48	Shared	66.6667	100	4	6	8
21	6x49	Shared	0	0	4	4	5
22	7x34	Shared	66.6667	100	5	5	5
23	7x42	Shared	66.6667	50	5	4	7
24	7x45	Shared	33.3333	87.5	6	4	9
25	7x49	Shared	0	75	4	4	9
26	7x53	Shared	66.6667	100	5	5	9
27	8x50	Shared	66.6667	75	4	4	9
28	Lig	Shared	100	100	18	16	0
29	1x39	mop_on	33.3333	37.5	3	4	7
30	1x53	mop_on	0	0	1	4	9
31	2x44	mop_on	0	0	3	4	6
32	2x50	mop_on	0	100	3	5	9
33	2x64	mop_on	0	12.5	3	4	5
34	3x32	mop_on	0	50	2	4	6
35	3x37	mop_on	33.3333	50	3	4	7
36	3x38	mop_on	0	50	3	4	7
37	I2x56	mop_on	0	25	2	4	4
38	4x41	mop_on	0	0	2	4	4
39	5x44	mop_on	0	50	3	4	5
40	6x52	mop_on	0	25	3	4	8
41	7x35	mop_on	0	50	2	4	4
42	7x52	mop_on	0	0	1	4	8
43	7x55	mop_on	0	12.5	2	4	6

Orange: nodes, hubs and links specific of mop_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of mop_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	mop_off Recurrence	mop_on Recurrence	mop_off Hub1?	mop_on Hub1?	mop_off Hub2?	mop_on Hub2?	ConSurf1	ConSurf2
1	1x43	2x58	mop_off	12.4282	1.54081	No	No	No	No	6	8
2	2x58	2x61	mop_off	10.9162	0	No	No	No	No	8	6
3	1x42	2x57	mop_off	13.9159	3.07844	Yes	No	Yes	Yes	7	7
4	3x40	6x44	mop_off	84.8564	0	No	No	Yes	No	8	9
5	3x40	3x41	mop_off	81.3486	0	No	No	No	No	8	6
6	3x41	4x49	mop_off	79.8609	0	No	No	No	No	6	7
7	3x42	4x49	mop_off	64.9592	0	No	No	No	No	7	7
8	2x45	3x42	mop_off	64.1609	0	No	No	No	No	9	7
9	2x41	4x46	mop_off	66.2171	2.59555	No	No	No	No	6	7
10	2x41	4x42	mop_off	64.2939	0	No	No	No	No	6	7
11	2x42	4x42	mop_off	63.3142	2.59555	Yes	Yes	No	No	7	7
12	3x46	6x37	mop_off	54.1397	0	No	No	No	No	8	7
13	3x50	6x37	mop_off	53.16	0	No	No	No	No	9	7
14	3x50	6x33	mop_off	51.0614	0	No	No	No	No	9	7
15	2x39	6x33	mop_off	50.124	0	No	No	No	No	8	7
16	2x37	2x39	mop_off	48.993	0	No	No	No	No	8	8
17	2x37	2x40	mop_off	47.8319	3.88538	No	No	No	No	8	8
18	2x40	I1x50	mop_off	28.8721	0	No	No	No	No	8	7
19	8x53	I1x50	mop_off	29.1684	0	No	No	No	No	5	7
20	1x60	8x53	mop_off	26.4469	0	Yes	No	No	No	5	5
21	2x40	8x50	mop_off	17.7744	7.71039	No	No	Yes	Yes	8	9
22	3x38	4x49	mop_off	14.1578	0	No	Yes	No	No	7	7
23	3x38	4x50	mop_off	12.5733	3.80913	No	Yes	Yes	Yes	7	9
24	2x60	3x28	mop_off	13.0813	0	No	No	No	No	6	5
25	2x56	3x28	mop_off	11.8778	0	No	No	No	No	6	5
26	E2	Lig	mop_off	38.7179	0	Yes	Yes	Yes	Yes	4	0
27	E1x50	E2	mop_off	17.7926	0	Yes	Yes	Yes	Yes	8	4
28	3x43	6x44	mop_off	58.6695	0	No	No	Yes	No	8	9
29	3x43	6x41	mop_off	57.6293	0	No	No	No	No	8	8
30	5x54	6x41	mop_off	56.577	0	No	No	No	No	8	8
31	5x58	5x61	mop_off	51.0735	0	Yes	Yes	No	No	9	8
32	3x51	5x61	mop_off	25.9571	0	Yes	Yes	No	No	8	8
33	1x60	I1x48	mop_off	13.8071	0	Yes	No	No	No	5	6
34	I1x48	I1x51	mop_off	12.3193	0	No	No	No	No	6	6
35	5x44	5x47	mop_off	12.3314	0.149315	No	Yes	Yes	Yes	5	8
36	5x47	6x49	mop_off	10.8316	8.54592	Yes	Yes	Yes	Yes	8	5
37	6x27	I3	mop_off	14.8171	2.18572	No	No	Yes	Yes	3	4
38	6x27	6x29	mop_off	13.6135	0	No	No	No	No	3	5
39	8x47	8x50	mop_off	12.3072	3.88538	No	No	Yes	Yes	8	9
40	2x60	Lig	mop_off	13.3293	1.27077	No	No	Yes	Yes	6	0
41	6x44	7x45	mop_off	15.9298	0.733869	Yes	No	Yes	Yes	9	9
42	3x36	6x52	mop_off	17.345	0	No	No	No	Yes	7	8
43	1x43	2x57	Shared	13.928	13.6639	No	No	Yes	Yes	6	7
44	7x42	Lig	Shared	31.2005	17.867	Yes	Yes	Yes	Yes	7	0
45	3x36	Lig	Shared	82.2558	63.71	No	No	Yes	Yes	7	0
46	3x36	6x48	Shared	100	63.9197	No	No	Yes	Yes	7	8
47	6x48	7x45	Shared	14.3211	100	Yes	Yes	Yes	Yes	8	9
48	7x45	7x49	Shared	20.8406	99.5489	Yes	Yes	Yes	Yes	9	9
49	2x50	7x49	Shared	12.3314	10.9858	No	Yes	Yes	Yes	9	9
50	6x44	6x48	Shared	86.0962	35.4227	Yes	No	Yes	Yes	9	8
51	2x45	4x46	Shared	67.1606	51.1199	No	No	No	No	9	7
52	2x42	3x46	Shared	55.2464	74.6164	Yes	Yes	No	No	7	8
53	3x34	4x50	Shared	10.8316	10.163	Yes	Yes	Yes	Yes	4	9
54	6x52	Lig	Shared	10.5171	71.6777	No	Yes	Yes	Yes	8	0
55	5x54	5x58	Shared	54.182	24.5322	No	No	Yes	Yes	8	9
56	3x54	5x61	Shared	27.2634	39.6829	No	No	No	No	8	8
57	5x35	E2	Shared	10.3538	18.8137	No	No	Yes	Yes	3	4
58	5x47	6x52	Shared	26.6646	12.8951	Yes	Yes	No	Yes	8	8
59	3x54	5x65	Shared	24.8382	37.6021	No	No	No	No	8	8
60	5x65	I3	Shared	23.4533	19.2935	No	No	Yes	Yes	8	4
61	6x29	6x32	Shared	12.1258	12.7013	No	No	Yes	No	5	7
62	7x34	Lig	Shared	13.2991	21.9208	Yes	Yes	Yes	Yes	5	0
63	2x57	7x42	Shared	26.8521	17.1617	Yes	Yes	Yes	Yes	7	7
64	7x34	7x35	mop_on	5.38857	11.6085	Yes	Yes	No	Yes	5	4
65	1x43	1x47	mop_on	0	10.6713	No	No	No	No	6	6
66	6x48	6x52	mop_on	0	74.2383	Yes	Yes	No	Yes	8	8
67	7x49	7x53	mop_on	5.9873	90.555	Yes	Yes	Yes	Yes	9	9
68	3x46	7x53	mop_on	0	75.309	No	No	Yes	Yes	8	9
69	2x42	4x46	mop_on	0	54.1697	Yes	Yes	No	No	7	7
70	2x45	4x50	mop_on	4.04596	50.0905	No	No	Yes	Yes	9	9
71	2x48	4x50	mop_on	3.15089	37.2431	No	No	Yes	Yes	6	9
72	1x54	2x48	mop_on	0	36.1311	No	No	No	No	7	6
73	1x54	2x44	mop_on	1.57847	35.0129	No	No	No	Yes	7	6
74	1x57	2x44	mop_on	4.71122	31.6199	No	No	No	Yes	7	6
75	1x53	1x57	mop_on	0	17.6542	No	Yes	No	No	9	7
76	1x53	7x55	mop_on	0	13.9753	No	Yes	No	Yes	9	6
77	1x57	8x50	mop_on	6.25945	13.791	No	No	Yes	Yes	7	9
78	2x42	3x49	mop_on	7.58996	21.0916	Yes	Yes	No	No	7	8
79	3x32	Lig	mop_on	1.27608	12.7013	No	Yes	Yes	Yes	6	0
80	2x56	3x32	mop_on	0	11.8912	No	No	No	Yes	6	6
81	2x56	3x31	mop_on	4.85637	10.4267	No	No	No	No	6	5
82	2x63	Lig	mop_on	0	45.5952	No	No	Yes	Yes	6	0
83	2x63	E1x50	mop_on	1.58452	44.5468	No	No	Yes	Yes	6	8
84	3x25	E1x50	mop_on	1.57242	31.1656	No	No	Yes	Yes	9	8
85	3x25	E2	mop_on	0	59.3703	No	No	Yes	Yes	9	4
86	3x29	Lig	mop_on	0	34.1805	No	No	Yes	Yes	5	0
87	3x29	E2x50	mop_on	1.34865	31.9408	No	No	No	No	5	9
88	3x25	E2x50	mop_on	0.00604778	30.7907	No	No	No	No	9	9
89	5x54	6x44	mop_on	0	35.105	No	No	Yes	No	8	9
90	3x47	5x54	mop_on	1.32446	10.0137	No	No	No	No	9	8
91	3x47	5x57	mop_on	0	12.8221	No	No	No	No	9	7
92	3x49	I2x56	mop_on	0	15.0268	No	No	No	Yes	8	4
93	3x50	5x58	mop_on	0	24.6053	No	No	Yes	Yes	9	9
94	3x50	7x53	mop_on	0	29.323	No	No	Yes	Yes	9	9
95	3x51	5x57	mop_on	9.31962	11.5513	Yes	Yes	No	No	8	7
96	3x50	5x61	mop_on	0	41.5859	No	No	No	No	9	8
97	5x36	E2	mop_on	0.350771	10.5188	No	No	Yes	Yes	4	4
98	5x34	5x35	mop_on	8.8358	16.1451	No	No	No	No	3	3
99	5x34	5x38	mop_on	1.58452	13.4987	No	No	No	No	3	4
100	6x26	I3	mop_on	5.61839	10.8778	No	No	Yes	Yes	4	4
101	5x65	6x33	mop_on	0	16.6661	No	No	No	No	8	7
102	6x29	6x33	mop_on	0	14.8521	No	No	No	No	5	7
103	5x38	5x42	mop_on	0	10.8111	No	No	No	No	4	3

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
1x39	2x57	Shared	10.9433	4.54125	1	0	2	2
1x39	7x42	mop_off	3.64	0	1	0	2	1
2x56	3x28	mop_off	4.76	0	0	0	2	2
2x57	7x42	Shared	7.42667	9.3775	1	0	2	1
2x60	7x42	Shared	8.26667	8.455	1	1	1	1
2x60	Lig	Shared	6.25	11.7838	1	1	1	0
2x63	E1x50	Shared	10.5467	7.6275	0	1	1	2
E1x49	E2	Shared	9.89	6.97	1	0	2	1
3x25	E1x50	Shared	3.48	6.04	1	1	2	2
E1x50	E2x50	Shared	8.27	16.975	1	1	2	2
3x22	E2	Shared	11.6967	9.42	1	1	2	1
3x25	E2x50	Shared	7.28	7.28	1	1	2	2
3x32	7x42	Shared	7.28333	8.05	1	1	1	1
3x32	Lig	Shared	15.0367	9.49375	1	1	1	0
3x33	4x60	Shared	8.41	5.365	1	1	1	2
3x33	Lig	Shared	6.43667	8.61875	1	1	1	0
3x36	6x48	Shared	6.59	5.8175	1	1	1	2
3x36	6x52	mop_off	3.50333	0	1	1	1	1
3x36	Lig	Shared	7.76333	8.55	1	1	1	0
3x37	5x43	Shared	5.24	5.8975	0	0	2	1
E2	E2	Shared	44.6667	31.705	1	1	1	1
E2	E2x51	Shared	13	5.05125	1	1	1	2
E2	E2x52	Shared	4.46333	3.80375	1	1	1	1
E2x52	Lig	mop_off	6.01333	0	1	0	1	0
5x35	E2	Shared	9.28333	7.20625	1	1	2	1
5x36	E2	Shared	12.05	8.0175	1	1	1	1
5x40	6x55	mop_off	4.55333	0	1	0	1	1
5x43	Lig	Shared	4.62667	5.63625	1	1	1	0
5x47	6x52	Shared	15.84	8.06125	0	1	2	1
6x51	Lig	Shared	5.19667	4.645	0	1	1	0
6x52	Lig	Shared	4.16333	3.66	1	1	1	0
6x54	7x34	Shared	7.39333	6.75375	0	0	2	1
6x54	7x37	mop_off	4.48	0	0	0	2	2
6x55	Lig	Shared	16.1667	5.09375	1	0	1	0
6x58	7x30	mop_off	4.97333	0	0	0	2	2
6x58	7x34	Shared	8.89333	9.86	0	0	2	1
E3	E3	mop_off	3.38667	0	1	0	1	1
7x30	E3	Shared	7.58333	11.1975	1	0	2	1
7x34	7x35	Shared	5.29333	4.4975	1	1	1	2
7x34	7x38	Shared	6.26667	6.31375	1	1	1	1
7x34	Lig	Shared	5.12333	3.665	1	1	1	0
7x38	Lig	Shared	3.38667	6.15125	1	1	1	0
7x42	Lig	Shared	5.99	4.3925	1	1	1	0
5x36	5x40	Shared	5.4	7.25625	1	1	1	1
5x36	Lig	mop_off	4.29	0	1	1	1	0
5x40	Lig	mop_off	9.21667	0	1	0	1	0
E2	Lig	mop_off	19.52	0	1	1	1	0
E3	Lig	mop_off	6.13	0	1	0	1	0
3x29	E2x50	Shared	3.27	3.475	0	1	1	2
5x44	5x47	Shared	3.21667	4.1525	0	1	2	2
3x33	5x39	mop_off	3.12333	0	1	1	1	2
E1x50	E2	mop_off	2.77667	0	1	1	2	1
4x63	E2	Shared	2.57667	3.76625	1	1	2	1
2x60	3x28	mop_off	2.38667	0	1	1	1	2
5x32	E2	Shared	2.21	3.24125	0	0	2	1
7x31	E3	mop_off	1.88	0	1	0	2	1
5x37	6x59	mop_off	1.56333	0	0	0	2	2
1x39	7x35	mop_on	0	11.5712	1	0	2	2
1x39	7x38	mop_on	0	6.7975	1	0	2	1
2x56	3x32	mop_on	0	5.7825	0	0	2	1
2x60	3x32	mop_on	0	4.73375	1	1	1	1
2x63	Lig	mop_on	0	4.75	0	1	1	0
3x29	4x64	mop_on	0	3.8575	0	1	1	2
3x29	Lig	mop_on	0	5.1675	0	1	1	0
5x39	E2	mop_on	0	4.10875	0	0	2	1
5x31	E2	mop_on	0	4.195	0	1	2	1
5x44	6x52	mop_on	0	5.09375	0	1	2	1
6x48	6x52	mop_on	0	7.2725	1	1	2	1
6x51	7x37	mop_on	0	3.885	0	1	1	2
6x54	7x30	mop_on	0	5.21375	0	0	2	2
3x28	E1x50	mop_on	0	3.6775	0	0	2	2
5x40	6x59	mop_on	0	3.4125	1	0	1	2
3x25	E2	mop_on	0	3.38	1	1	2	1
5x37	5x40	mop_on	0	1.575	0	0	2	1
Lig	NT	mop_on	0	0.445	1	1	0	1
1x29	NT	mop_on	0	0.3825	0	0	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	mop_off	7UL4-μ-Alvimopan 4DKL-μ-Beta-funaltrexamine 8QOT-μ-Nanobody E
	mop_on	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2

Network Difference
Value	mop_off	mop_on
I_min	3.28667	3.45
Number of Linked Nodes	264	260
Number of Specific Nodes	6 (2.27%)	2 (0.77%)
Number of Shared Nodes	258 (97.73%)	258 (99.23%)
Number of Links	286	281
Number of Specific Links	109 (38.11%)	104 (37.01%)
Number of Shared Links	177 (61.89%)	177 (62.99%)
Number of Hubs	28	36
Number of Specific Hubs	7 (25.00%)	15 (41.67%)
Number of Shared Hubs	21 (75.00%)	21 (58.33%)
Average % Shared Neighbours (Jaccard)	49.87
Average % Shared Neighbours (Otsuka)	58.59
Average % Shared Neighbours (Overlap Coefficient)	67.06
Average % Shared Cliques (k3-6)	56.52
Graphlets Similarity	0.469493

Paths Difference
Value	mop_off	mop_on
Number Of Nodes in MetaPath	62	59
Specific Nodes in MetaPath	27 (43.55%)	24 (40.68%)
Shared Nodes in MetaPath	258 (97.73%)	258 (97.73%)
Number Of Links MetaPath	63	61
Specific Links in MetaPath	42 (66.67%)	40 (65.57%)
Shared Links in MetaPath	177 (61.89%)	177 (61.89%)
Number of Shortest Paths	33361	62330
Length Of Smallest Path	3	3
Average Path Length	15.1767	14.1294
Length of Longest Path	43	33
Minimum Path Strength	0.51	0.37375
Average Path Strength	6.01726	5.71725
Maximum Path Strength	14.99	18.6969
Minimum Path Correlation	0.706667	0.70375
Average Path Correlation	0.929642	0.919873
Maximum Path Correlation	0.99	0.99125
Minimum % Of Corr. Nodes	3.22581	3.84615
Average % Of Corr. Nodes	48.0786	42.254
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	32.7675	45.6305
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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