Orange: nodes, hubs and links specific of npy1_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of npy1_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner npy1_on_gp Avg Int. Strength npy1_off Avg Int. Strength npy1_on_gp Num Of Links npy1_off Num Of Links ConSurf
1G.HN.43 npy1_on_gp2.480409
2G.HN.52 npy1_on_gp3.93250404
3G.S1.02 npy1_on_gp5.760405
4G.S1.04 npy1_on_gp2.510507
5G.S1.06 npy1_on_gp3.50750409
6G.S1.07 npy1_on_gp2.7750409
7G.s1h1.06 npy1_on_gp2.650409
8G.H1.01 npy1_on_gp4.320609
9G.H1.04 npy1_on_gp3.621430707
10G.H1.08 npy1_on_gp2.7650409
11G.S2.01 npy1_on_gp3.820608
12G.S2.08 npy1_on_gp8.42750405
13G.S3.01 npy1_on_gp4.0250404
14G.S3.03 npy1_on_gp7.0850607
15G.S3.04 npy1_on_gp6.26750407
16G.S3.05 npy1_on_gp3.0160507
17G.S3.06 npy1_on_gp3.0080506
18G.S3.07 npy1_on_gp3.87750409
19G.S3.08 npy1_on_gp5.38250409
20G.s3h2.03 npy1_on_gp5.7380509
21G.H2.02 npy1_on_gp3.3550408
22G.H2.03 npy1_on_gp4.580409
23G.H2.06 npy1_on_gp4.676670609
24G.H2.07 npy1_on_gp6.2560509
25G.H2.10 npy1_on_gp2.5780507
26G.h2s4.01 npy1_on_gp2.9340509
27G.S4.04 npy1_on_gp3.9160509
28G.S4.05 npy1_on_gp2.133330607
29G.S4.06 npy1_on_gp4.20750407
30G.s4h3.01 npy1_on_gp4.65750406
31G.s4h3.04 npy1_on_gp4.7660508
32G.s4h3.11 npy1_on_gp5.63250409
33G.s4h3.15 npy1_on_gp4.030409
34G.H3.01 npy1_on_gp4.00750409
35G.H3.02 npy1_on_gp2.250408
36G.H3.06 npy1_on_gp2.823330606
37G.H3.09 npy1_on_gp4.30250409
38G.H3.13 npy1_on_gp2.840506
39G.H3.17 npy1_on_gp4.8680505
40G.H3.18 npy1_on_gp5.420609
41G.S5.03 npy1_on_gp2.2860508
42G.S5.04 npy1_on_gp4.2080509
43G.S5.05 npy1_on_gp2.510609
44G.S5.06 npy1_on_gp4.026670609
45G.S5.07 npy1_on_gp3.38250409
46G.HG.04 npy1_on_gp3.8960508
47G.HG.07 npy1_on_gp4.42250409
48G.HG.13 npy1_on_gp4.9080506
49G.hgh4.01 npy1_on_gp4.770405
50G.hgh4.02 npy1_on_gp4.658570708
51G.hgh4.05 npy1_on_gp5.89750406
52G.H4.03 npy1_on_gp4.9980504
53G.H4.05 npy1_on_gp5.98250405
54G.H4.10 npy1_on_gp5.6950406
55G.H4.11 npy1_on_gp2.1520507
56G.H4.12 npy1_on_gp4.070405
57G.h4s6.02 npy1_on_gp4.30250407
58G.h4s6.11 npy1_on_gp3.2450407
59G.S6.02 npy1_on_gp4.8140508
60G.S6.03 npy1_on_gp5.7760505
61G.S6.04 npy1_on_gp6.4650409
62G.S6.05 npy1_on_gp3.140505
63G.s6h5.01 npy1_on_gp3.2650409
64G.s6h5.02 npy1_on_gp2.7650407
65G.H5.03 npy1_on_gp4.43750408
66G.H5.07 npy1_on_gp1.680609
67G.H5.08 npy1_on_gp5.8640508
68G.H5.11 npy1_on_gp3.7680508
69G.H5.23 npy1_on_gp3.0750404
70G.H5.25 npy1_on_gp2.66750407
71b.1x11 npy1_on_gp2.090608
72b.1x19 npy1_on_gp5.0950406
73b.h2x5 npy1_on_gp3.8620505
74b.lhb1x11 npy1_on_gp2.5780504
75b.b1x4 npy1_on_gp4.30250407
76b.b1x6 npy1_on_gp6.11750409
77b.l1x3 npy1_on_gp6.5280509
78b.l1x6 npy1_on_gp6.81250409
79b.l1x7 npy1_on_gp3.80750409
80b.b2x1 npy1_on_gp7.340508
81b.b2x3 npy1_on_gp4.3180506
82b.b2x5 npy1_on_gp3.888330607
83b.b3x3 npy1_on_gp2.48750408
84b.b3x4 npy1_on_gp3.3920509
85b.b3x6 npy1_on_gp4.670409
86b.l3x1 npy1_on_gp4.018330609
87b.l3x2 npy1_on_gp2.7950409
88b.b4x2 npy1_on_gp2.870408
89b.b4x3 npy1_on_gp2.728330607
90b.b4x4 npy1_on_gp3.6020508
91b.b4x5 npy1_on_gp2.168330607
92b.b4x6 npy1_on_gp7.6580509
93b.b4x7 npy1_on_gp6.25750408
94b.l4x1 npy1_on_gp3.1350405
95b.l4x2 npy1_on_gp7.7320504
96b.b5x2 npy1_on_gp3.5640507
97b.b5x3 npy1_on_gp4.6650609
98b.b5x5 npy1_on_gp4.21250405
99b.b5x7 npy1_on_gp3.18750807
100b.l5x1 npy1_on_gp2.160508
101b.l5x5 npy1_on_gp4.301430709
102b.b6x3 npy1_on_gp2.60250408
103b.b6x5 npy1_on_gp2.7460506
104b.l6x1 npy1_on_gp2.57750406
105b.l6x5 npy1_on_gp5.3280504
106b.b7x1 npy1_on_gp5.038330604
107b.b7x2 npy1_on_gp2.2220508
108b.b7x3 npy1_on_gp2.2380509
109b.b7x4 npy1_on_gp2.2460508
110b.l7x1 npy1_on_gp1.80250409
111b.l7x2 npy1_on_gp3.778330609
112b.b8x3 npy1_on_gp2.103330606
113b.b8x4 npy1_on_gp3.004290706
114b.l8x1 npy1_on_gp2.560405
115b.l8x3 npy1_on_gp2.5650403
116b.l8x7 npy1_on_gp5.99250403
117b.l8x8 npy1_on_gp3.94750404
118b.b9x3 npy1_on_gp3.24750406
119b.b9x4 npy1_on_gp4.5760509
120b.l9x3 npy1_on_gp2.1980509
121b.l9x6 npy1_on_gp2.618330608
122b.b10x1 npy1_on_gp1.9450409
123b.b10x2 npy1_on_gp2.39750406
124b.b10x3 npy1_on_gp1.75750408
125b.b10x4 npy1_on_gp4.09750406
126b.b10x5 npy1_on_gp3.606250809
127b.l10x1 npy1_on_gp5.9620503
128b.l10x4 npy1_on_gp4.4580503
129b.b11x2 npy1_on_gp4.94750407
130b.b11x3 npy1_on_gp3.2240505
131b.b11x4 npy1_on_gp2.840509
132b.b11x6 npy1_on_gp2.610509
133b.l11x2 npy1_on_gp3.8320509
134b.b12x3 npy1_on_gp2.7650408
135b.b12x6 npy1_on_gp6.591430708
136b.l12x3 npy1_on_gp4.490405
137b.b13x3 npy1_on_gp6.77250404
138b.b13x7 npy1_on_gp6.0920507
139b.l13x3 npy1_on_gp5.796670609
140b.l13x6 npy1_on_gp3.3450609
141b.l13x7 npy1_on_gp3.426670609
142b.b14x1 npy1_on_gp3.490408
143b.b14x3 npy1_on_gp3.4060505
144b.b15x1 npy1_on_gp5.328330609
145b.b15x2 npy1_on_gp5.680406
146b.b15x3 npy1_on_gp3.4060509
147b.l15x1 npy1_on_gp5.42250407
148b.l15x2 npy1_on_gp5.04250409
149b.b16x5 npy1_on_gp4.21750405
150b.b16x6 npy1_on_gp6.468330608
151b.b16x7 npy1_on_gp4.630409
152b.l16x2 npy1_on_gp6.460409
153b.l16x3 npy1_on_gp6.22750403
154b.b17x5 npy1_on_gp4.3060507
155b.b17x7 npy1_on_gp5.170408
156b.l17x3 npy1_on_gp5.971670609
157b.l17x7 npy1_on_gp2.96250407
158b.b18x3 npy1_on_gp4.1040508
159b.l18x1 npy1_on_gp5.493750806
160b.b19x2 npy1_on_gp5.8420506
161b.b19x4 npy1_on_gp4.5780508
162b.b19x5 npy1_on_gp2.71750405
163b.b19x6 npy1_on_gp4.86250409
164b.l19x2 npy1_on_gp4.880409
165b.b20x2 npy1_on_gp2.630406
166b.b20x4 npy1_on_gp4.494290708
167b.b20x6 npy1_on_gp5.6180506
168b.b20x7 npy1_on_gp5.660409
169b.l20x1 npy1_on_gp2.92250406
170b.b21x1 npy1_on_gp8.1080507
171b.b21x2 npy1_on_gp3.4250406
172b.b21x7 npy1_on_gp6.303330605
173b.l21x2 npy1_on_gp4.58250404
174b.l21x5 npy1_on_gp3.74250404
175b.l21x9 npy1_on_gp4.610406
176b.b22x1 npy1_on_gp3.1750408
177b.b22x3 npy1_on_gp1.663330606
178b.b22x5 npy1_on_gp5.213330607
179b.l22x1 npy1_on_gp2.35750409
180b.l22x3 npy1_on_gp3.690409
181b.l22x4 npy1_on_gp2.83750409
182b.l22x5 npy1_on_gp4.256670609
183b.b23x1 npy1_on_gp2.323330605
184b.b23x2 npy1_on_gp3.46250406
185b.b23x3 npy1_on_gp3.9650407
186b.b23x6 npy1_on_gp5.021430707
187b.l23x1 npy1_on_gp7.58250406
188b.l23x2 npy1_on_gp5.310408
189b.b24x2 npy1_on_gp4.9250405
190b.b24x4 npy1_on_gp3.780506
191b.b24x5 npy1_on_gp2.4320505
192b.l24x2 npy1_on_gp3.9750606
193b.l24x3 npy1_on_gp3.6850405
194b.b25x3 npy1_on_gp4.16750405
195b.b25x7 npy1_on_gp4.2550407
196b.l25x3 npy1_on_gp7.66750409
197b.l25x6 npy1_on_gp7.7260508
198b.l25x7 npy1_on_gp1.660407
199b.b26x2 npy1_on_gp3.36750407
200b.b26x3 npy1_on_gp2.554290706
201b.l26x1 npy1_on_gp3.6750607
202b.l26x3 npy1_on_gp5.820407
203b.l26x4 npy1_on_gp1.790509
204b.l26x5 npy1_on_gp4.0380505
205b.b27x1 npy1_on_gp2.7480506
206b.b27x3 npy1_on_gp3.573330608
207b.b27x5 npy1_on_gp4.5580509
208b.l27x1 npy1_on_gp10.250509
209b.l27x2 npy1_on_gp6.71250409
210b.b28x3 npy1_on_gp3.178570707
211b.b28x4 npy1_on_gp3.161670606
212b.b28x5 npy1_on_gp3.1750405
213b.b28x6 npy1_on_gp6.6160509
214b.b28x7 npy1_on_gp4.9350409
215g.h1x1 npy1_on_gp1.80750402
216g.h1x11 npy1_on_gp3.09750409
217g.h1x14 npy1_on_gp4.90409
218g.l1x4 npy1_on_gp5.2180508
219g.ctx3 npy1_on_gp4.182860709
220g.ctx4 npy1_on_gp3.8350407
221g.ctx5 npy1_on_gp2.7950409
222g.ctx6 npy1_on_gp2.1740506
223g.ctx9 npy1_on_gp2.40750406
224g.ctx14 npy1_on_gp4.9420509
225g.ctx16 npy1_on_gp5.0350608
226NT.L35 npy1_on_gp4.7284.4975523
2271x31 npy1_on_gp2.265.255424
2281x43 npy1_on_gp4.23254.1775427
2291x53 npy1_on_gp3.2424.77529
2301x56 npy1_on_gp3.076.28517
2311x57 npy1_on_gp3.347149.4425727
2322x42 npy1_on_gp4.515.2775427
2332x45 npy1_on_gp3.279.35667439
2342x46 npy1_on_gp4.45.7175629
2352x50 npy1_on_gp5.2664.76167539
2362x53 npy1_on_gp2.8056.41427
2372x56 npy1_on_gp3.753.815517
2382x59 npy1_on_gp3.6557.895436
2392x60 npy1_on_gp4.939.4725626
240E1x49 npy1_on_gp7.157511.575425
2413x28 npy1_on_gp4.27.31415
2423x34 npy1_on_gp1.956.36525
2433x35 npy1_on_gp3.14756.0875428
2443x37 npy1_on_gp3.2655.5775626
2453x38 npy1_on_gp4.37812.0225527
2463x40 npy1_on_gp4.21255.2575427
2473x43 npy1_on_gp3.6045.96518
2483x46 npy1_on_gp2.87255.3525428
2493x51 npy1_on_gp6.1058.80667437
2503x53 npy1_on_gp2.5565.305518
2513x54 npy1_on_gp2.14754.7375428
2523x55 npy1_on_gp5.36758.755436
253I2.P145 npy1_on_gp2.6682.8825528
2544x46 npy1_on_gp2.727513.455417
2554x50 npy1_on_gp5.78510.1033439
2564x53 npy1_on_gp2.11753.36418
2574x57 npy1_on_gp3.7885.87527
2584x65 npy1_on_gp2.15758.04833435
259E2.E182 npy1_on_gp7.96758.58421
260E2.K195 npy1_on_gp8.03511.315433
261E2x50 npy1_on_gp3.30256.78167439
2625x40 npy1_on_gp4.90759.795425
2635x44 npy1_on_gp1.81758.525416
2645x461 npy1_on_gp5.1855.51436
2655x50 npy1_on_gp3.1055.46833439
2665x58 npy1_on_gp4.748575.24333739
2675x61 npy1_on_gp1.60755.3428
2685x64 npy1_on_gp3.3585.73333535
2695x65 npy1_on_gp3.47252.85418
2705x70 npy1_on_gp6.0750404
2716x32 npy1_on_gp2.9757.70333437
2726x40 npy1_on_gp2.6154.5975427
2736x44 npy1_on_gp2.52256.86439
2746x47 npy1_on_gp2.98253.785428
2756x59 npy1_on_gp4.8933313.0325624
2767x30 npy1_on_gp5.197510.9675423
2777x34 npy1_on_gp5.4259.065435
2787x35 npy1_on_gp3.2656.9225424
2797x42 npy1_on_gp4.01812.245527
2807x46 npy1_on_gp2.46756.505418
2817x49 npy1_on_gp2.6946.18519
2827x52 npy1_on_gp3.8555.16438
2838x47 npy1_on_gp3.8453.11167438
2848x48 npy1_on_gp4.0667.71535
2851x39 Shared3.6266710.772657
2861x50 Shared5.5664.03625549
2872x57 Shared3.625715.9475747
288E1x50 Shared7.063339.604658
289E1x52 Shared5.6589.91375547
2903x32 Shared5.58755.89125446
2913x49 Shared6.99756.04667468
2923x50 Shared2.617.21125549
293E2.F184 Shared3.9743.1975541
294E2.F202 Shared3.96257.158455
2955x47 Shared4.86756.755448
2966x48 Shared4.48.128558
2976x54 Shared4.44759.51125445
2987x38 Shared5.9429.2546
2998x50 Shared4.3965.687558
300Lig Shared16.93369.1057725130
3012x61 npy1_off2.423339.30625346
3023x30 npy1_off2.6356.91875246
3033x41 npy1_off2.536.261357
3044x61 npy1_off4.963337.73625345
3055x36 npy1_off7.923338.0725344
3065x39 npy1_off6.2866712.0425346
3076x36 npy1_off2.245.4125348
3086x37 npy1_off4.884.5575348
3096x58 npy1_off20.37.126154
310E3.H290 npy1_off08.26044
3117x53 npy1_off3.519.22375349
3128x58 npy1_off02.465040
   
Orange: nodes, hubs and links specific of npy1_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of npy1_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner npy1_on_gp Recurrence npy1_off Recurrence npy1_on_gp Hub1? npy1_off Hub1? npy1_on_gp Hub2? npy1_off Hub2? ConSurf1 ConSurf2
1b.b3x6 b.l1x5 npy1_on_gp13.89570YesNoNoNo97
2b.l1x5 b.l3x1 npy1_on_gp17.62890NoNoYesNo79
3b.l3x1 b.l5x5 npy1_on_gp34.14450YesNoYesNo99
4G.S2.01 b.l5x5 npy1_on_gp20.42690YesNoYesNo89
5G.S2.01 G.S3.08 npy1_on_gp31.9870YesNoYesNo89
6G.S1.07 G.S3.08 npy1_on_gp62.31120YesNoYesNo99
7G.S1.07 G.S4.04 npy1_on_gp1000YesNoYesNo99
8G.S4.04 G.S5.04 npy1_on_gp1000YesNoYesNo99
9G.S5.04 G.S5.06 npy1_on_gp1000YesNoYesNo99
10G.S5.06 G.S6.05 npy1_on_gp1000YesNoYesNo95
11G.H4.03 G.S6.05 npy1_on_gp1000YesNoYesNo45
12G.H4.03 G.HG.05 npy1_on_gp1000YesNoNoNo44
13G.HG.02 G.HG.05 npy1_on_gp1000NoNoNoNo94
14G.HG.02 G.HG.03 npy1_on_gp1000NoNoNoNo96
15G.HG.03 G.s4h3.02 npy1_on_gp1000NoNoNoNo69
16G.s4h3.02 G.s5hg.01 npy1_on_gp1000NoNoNoNo99
17G.s1h1.06 G.s5hg.01 npy1_on_gp1000YesNoNoNo99
18G.S5.07 G.s1h1.06 npy1_on_gp73.13410YesNoYesNo99
19G.S4.05 G.S5.07 npy1_on_gp18.72170YesNoYesNo79
20G.h2s4.01 b.l5x5 npy1_on_gp20.45210YesNoYesNo99
21G.S1.05 G.h2s4.01 npy1_on_gp20.51590NoNoYesNo99
22G.S1.05 G.S1.07 npy1_on_gp20.5490NoNoYesNo99
23G.H1.03 G.s1h1.06 npy1_on_gp35.7350NoNoYesNo99
24G.H1.03 G.H1.04 npy1_on_gp35.75190NoNoYesNo97
25G.H1.04 G.H1.08 npy1_on_gp34.92710YesNoYesNo79
26G.H1.04 G.S5.07 npy1_on_gp35.7360YesNoYesNo79
27G.H1.08 G.H5.07 npy1_on_gp34.54150YesNoYesNo99
28G.H1.04 G.S5.05 npy1_on_gp36.53520YesNoYesNo79
29G.H5.07 G.S5.05 npy1_on_gp69.05640YesNoYesNo99
30G.S4.05 G.S5.05 npy1_on_gp18.31930YesNoYesNo79
31G.S5.07 G.s6h5.01 npy1_on_gp18.69340YesNoYesNo99
32G.S5.05 G.s6h5.01 npy1_on_gp18.2710YesNoYesNo99
33G.H5.07 G.H5.11 npy1_on_gp1000YesNoYesNo98
34G.H3.12 G.H3.18 npy1_on_gp19.65910NoNoYesNo89
35G.H2.08 G.H3.18 npy1_on_gp19.49730NoNoYesNo89
36G.H2.08 G.H3.17 npy1_on_gp19.46390NoNoYesNo85
37G.H3.17 b.l25x6 npy1_on_gp19.29210YesNoYesNo58
38G.s3h2.03 b.l7x2 npy1_on_gp10.8970YesNoYesNo99
39b.b2x1 b.l27x1 npy1_on_gp17.75530YesNoYesNo89
40G.H2.10 b.b2x1 npy1_on_gp12.00610YesNoYesNo78
41G.H2.02 G.H2.07 npy1_on_gp19.1940YesNoYesNo89
42b.b10x1 b.l9x6 npy1_on_gp14.19660YesNoYesNo98
43b.l23x1 b.l25x6 npy1_on_gp13.67670YesNoYesNo68
44G.H5.11 G.H5.15 npy1_on_gp1000YesNoNoNo88
45G.H5.15 I2.P145 npy1_on_gp1000NoNoYesNo88
465x64 I2.P145 npy1_on_gp99.80640YesNoYesNo58
473x54 G.H5.19 npy1_on_gp22.56290YesNoNoNo87
483x54 5x64 npy1_on_gp97.88730YesNoYesNo85
493x54 G.H5.23 npy1_on_gp73.550YesNoYesNo84
503x53 G.H5.19 npy1_on_gp22.39530YesNoNoNo87
513x53 G.H5.23 npy1_on_gp22.4030YesNoYesNo84
523x50 G.H5.23 npy1_on_gp51.00530YesYesYesNo94
53b.b27x5 b.l27x1 npy1_on_gp23.61290YesNoYesNo99
54b.b27x1 g.ctx5 npy1_on_gp11.49040YesNoYesNo69
553x46 3x50 npy1_on_gp50.45280YesNoYesYes89
562x46 2x50 npy1_on_gp16.66610YesNoYesNo99
572x50 7x46 npy1_on_gp22.54731.12268YesNoYesNo98
587x42 7x46 npy1_on_gp17.09230YesNoYesNo78
593x43 3x46 npy1_on_gp22.57940YesNoYesNo88
603x49 3x53 npy1_on_gp43.95391.12268YesYesYesNo88
612x42 3x49 npy1_on_gp38.00310YesNoYesYes78
625x461 Lig npy1_on_gp41.00990YesNoYesYes60
633x37 5x461 npy1_on_gp22.56292.24282YesNoYesNo66
643x37 3x41 npy1_on_gp23.82790YesNoNoYes67
655x46 5x461 npy1_on_gp22.54720NoNoYesNo56
663x41 5x46 npy1_on_gp22.80230NoYesNoNo75
67G.S2.01 b.l7x2 npy1_on_gp10.91580YesNoYesNo89
68G.S3.08 G.s3h2.03 npy1_on_gp11.05470YesNoYesNo99
69G.H3.12 G.S1.07 npy1_on_gp19.75610NoNoYesNo89
70G.H2.02 b.l9x6 npy1_on_gp18.68320YesNoYesNo88
71b.b27x1 b.b27x3 npy1_on_gp13.00340YesNoYesNo68
72b.b10x1 b.b11x6 npy1_on_gp10.78610YesNoYesNo99
73G.H2.07 G.S3.08 npy1_on_gp19.2390YesNoYesNo99
74b.b27x5 b.l25x3 npy1_on_gp14.23950YesNoYesNo99
752x42 3x46 Shared19.148142.9591YesNoYesNo78
762x42 3x45 Shared47.388143.8659YesNoNoNo77
773x45 4x49 Shared47.133245.6642NoNoNoNo77
783x41 4x49 Shared46.883646.5735NoYesNoNo77
791x39 2x61 npy1_off1.0357914.9327YesYesNoYes76
801x39 7x38 npy1_off4.6526927.8283YesYesYesYes76
817x34 7x38 npy1_off036.6421YesNoYesYes56
826x58 7x30 npy1_off010.1321NoYesYesNo43
837x34 Lig npy1_off1.554536.0503YesNoYesYes50
846x58 Lig npy1_off0.51506813.3198NoYesYesYes40
851x50 2x50 npy1_off2.4411950.3023YesYesYesNo99
862x50 3x39 npy1_off0.0075221152.0295YesNoNoNo99
873x39 6x44 npy1_off054.5822NoNoYesNo99
886x44 6x48 npy1_off0100YesNoYesYes98
893x32 6x48 npy1_off053.5789YesYesYesYes68
903x32 Lig npy1_off0.054287954.3028YesYesYesYes60
913x36 6x48 npy1_off0.0038325848.8951NoNoYesYes78
923x36 Lig npy1_off048.9053NoNoYesYes70
931x50 2x47 npy1_off0.12458641.3614YesYesNoNo99
941x53 7x53 npy1_off012.9058YesNoNoYes99
952x40 7x53 npy1_off033.8329NoNoNoYes89
961x57 2x40 npy1_off0.69674836.7005YesNoNoNo78
971x57 2x44 npy1_off0.52481337.6429YesNoNoNo75
981x54 2x44 npy1_off0.34988538.5801NoNoNoNo75
991x54 2x47 npy1_off040.4394NoNoNoNo79
1001x53 8x50 npy1_off011.8263YesNoYesYes98
1016x36 8x47 npy1_off013.0124NoYesYesNo88
1026x36 7x53 npy1_off020.2438NoYesNoYes89
1032x39 3x49 npy1_off5.4703633.9243NoNoYesYes78
1042x39 6x37 npy1_off034.8895NoNoNoYes78
1053x46 6x37 npy1_off042.0472YesNoNoYes88
1063x41 5x50 npy1_off061.7526NoYesYesNo79
1073x40 5x50 npy1_off0.0077903363.3376YesNoYesNo79
1083x40 6x44 npy1_off3.9552564.1224YesNoYesNo79
109E1x50 E1x52 npy1_off1.5407433.0226YesYesYesYes87
110E1x50 E2x50 npy1_off2.5769335.1791YesYesYesNo89
1114x65 E2x50 npy1_off041.8237YesNoYesNo59
1124x65 E2x52 npy1_off0.0014603141.2979YesNoNoNo54
113E2x52 Lig npy1_off056.7793NoNoYesYes40
114E1x51 E1x52 npy1_off028.509NoNoYesYes27
1152x67 E2.K195 npy1_off020.8128NoNoYesNo43
116E1x49 E2.K195 npy1_off6.55651e-0525.6718YesNoYesNo53
117E1x49 E1x51 npy1_off0.51549126.6243YesNoNoNo52
1184x61 Lig npy1_off011.4453NoYesYesYes50
1193x41 3x44 npy1_off011.0211NoYesNoNo77
1203x49 I2.W148 npy1_off021.082YesYesNoNo85
1213x55 3x56 npy1_off1.6259114.8844YesNoNoNo66
1223x52 3x56 npy1_off0.090408318.0315NoNoNoNo46
1233x52 I2.W148 npy1_off020.1041NoNoNoNo45
124E2.F202 E2x52 npy1_off0.51587819.9797YesYesNoNo54
1252x67 E2.V187 npy1_off018.8849NoNoNoNo42
126E2.V187 NT.F28 npy1_off017.0434NoNoNoNo20
127E2.F184 NT.F28 npy1_off016.124YesYesNoNo10
128E2.F184 E2x51 npy1_off011.1938YesYesNoNo13
1295x36 E2.F202 npy1_off2.5775213.302NoYesYesYes45

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
2x533x32npy1_off7.16500021
2x582x59Shared5.0552.890021
2x59E1x52Shared11.792.140212
2x593x24npy1_off6.8400212
2x603x28npy1_off7.3100211
2x607x38Shared11.63513.690212
2x63E1x50Shared13.5058.680211
2x647x31npy1_off4.3900221
2x67E2.T188npy1_off4.33500012
E1x49E2.K195Shared18.99517.030222
E1x50E1x52Shared18.0417.045212
3x25E1x50Shared5.8759.145221
E1x50E2x50Shared8.493.925212
3x25E2x50Shared7.283.645222
3x294x61Shared6.52.890021
3x294x65Shared153.160022
3x326x48npy1_off7.1200212
3x32LigShared5.4656.40210
3x334x61npy1_off5.5900221
3x366x48Shared10.573.520712
3x36Lignpy1_off8.6800710
3x375x461Shared7.7954.250221
3x415x461npy1_off6.5700021
4x615x39Shared9.87.220012
4x61Lignpy1_off9.05500010
4x65E2x50npy1_off4.57500022
4x65E2x52Shared4.572.610021
E2.E182E2.T180Shared10.5851.410212
E2.P183E2.V197Shared6.1853.530212
E2.F184E2x51npy1_off4.82500211
E2.V197E2x51Shared7.8651.310021
E2.F202E2x52Shared5.3752.392221
E2x52Lignpy1_off4.85500010
5x36E2.F202Shared8.557.482212
5x39E2.F202npy1_off5.67500022
5x335x36npy1_off8.3402021
5x33E3.H290npy1_off10.71502022
5x36E3.H290npy1_off12.97502212
5x376x60Shared13.679.110022
5x395x43Shared11.144.690021
5x406x59Shared12.28510.121211
5x40LigShared7.3056.471210
5x416x60Shared4.2452.430022
5x476x52Shared7.497.490021
6x516x55Shared6.8655.490021
6x52Lignpy1_off10.13500010
6x546x58npy1_off12.32501011
6x547x33Shared6.72.441012
6x547x34Shared9.6457.51011
6x54Lignpy1_off9.37501010
6x55LigShared24.0916.750210
6x58E3.I292npy1_off4.39501012
6x587x30npy1_off9.61501011
6x58LigShared7.98520.31010
6x59LigShared13.788.341210
7x277x30npy1_off12.3200021
7x347x38npy1_off4.52501212
7x34LigShared13.0256.411210
E2.E182NT.N22npy1_off6.57500212
E2.Q201E2x51npy1_off4.100021
2x563x32Shared3.8159.160221
E2.F184NT.F28npy1_off3.7500212
2x67E2.V187npy1_off3.6500011
E2.P183E2.T180npy1_off3.49500212
2x67E2.K195npy1_off3.45500012
E2.V187NT.F28npy1_off3.27500212
6x517x37Shared3.171.590022
E2.F184E2.L189npy1_off3.04500212
E3.A294Lignpy1_off2.60500010
5x365x37npy1_off2.42502212
4x565x461npy1_off2.16500221
3x21E1x50Shared2.111.410221
E2.Q185E3.I293npy1_off2.0600022
6x56Lignpy1_off2.0200010
E2.V187NT.E29npy1_off1.42500212
6x576x58npy1_off1.3100021
E2.F184E2.Q185Shared1.173.510212
2x532x56npy1_on_gp01.710022
2x533x36npy1_on_gp03.070021
2x562x60npy1_on_gp01.690221
2x567x38npy1_on_gp02.950222
2x593x28npy1_on_gp07.250211
2x59Lignpy1_on_gp02.340210
2x602x64npy1_on_gp01.570212
2x603x32npy1_on_gp02.830211
2x607x34npy1_on_gp01.30211
2x60Lignpy1_on_gp08.50210
2x63E2x50npy1_on_gp04.030212
2x63Lignpy1_on_gp017.510210
2x647x34npy1_on_gp06.490221
2x67Lignpy1_on_gp013.470010
E1x49E2.F184npy1_on_gp02.260221
E1x50Lignpy1_on_gp02.195210
3x21E1x52npy1_on_gp01.510222
3x24E1x52npy1_on_gp04.980022
3x254x65npy1_on_gp01.535222
3x283x29npy1_on_gp01.630212
3x283x32npy1_on_gp03.960211
3x28Lignpy1_on_gp03.960210
3x333x37npy1_on_gp01.690222
3x363x40npy1_on_gp01.470712
3x373x41npy1_on_gp03.890222
3x374x56npy1_on_gp04.80222
3x406x48npy1_on_gp08.220722
3x415x46npy1_on_gp02.440022
4x61E2x52npy1_on_gp04.780011
E2.T180E2x51npy1_on_gp02.590021
E2.E182E2.P183npy1_on_gp07.860211
E2.E182E2.N186npy1_on_gp013.150211
E2.E182Lignpy1_on_gp09.450210
E2.P183Lignpy1_on_gp05.020210
E2.F184E2.K195npy1_on_gp03.720212
E2.F184E2.V197npy1_on_gp07.870212
E2.F184Lignpy1_on_gp02.510210
E2.L189E2.N186npy1_on_gp01.370021
E2.N186Lignpy1_on_gp04.20210
E2.T188E2.V187npy1_on_gp06.350021
E2.V187Lignpy1_on_gp03.530210
E2x51Lignpy1_on_gp011.670210
5x366x59npy1_on_gp05.962211
5x36Lignpy1_on_gp010.332210
5x405x41npy1_on_gp01.571212
5x405x44npy1_on_gp01.471212
5x435x461npy1_on_gp09.320211
5x43Lignpy1_on_gp03.520210
5x446x56npy1_on_gp02.950221
5x446x59npy1_on_gp01.360221
5x465x461npy1_on_gp02.660021
5x461Lignpy1_on_gp04.510210
5x476x48npy1_on_gp02.890022
6x526x56npy1_on_gp01.570011
6x547x30npy1_on_gp02.261011
6x547x37npy1_on_gp05.591012
6x556x59npy1_on_gp01.350211
6x57E3.I292npy1_on_gp01.540022
6x596x60npy1_on_gp02.231212
7x27E3.I293npy1_on_gp01.520022
7x30E3.I293npy1_on_gp02.650212
7x33E3.I293npy1_on_gp01.430022
7x307x31npy1_on_gp05.10211
7x30Lignpy1_on_gp010.780210
7x31Lignpy1_on_gp09.540210

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
npy1_on_gp 8K6M-Y1-Neuropeptide-Y-Gi2/β1/γ1
npy1_off 5ZBH-Y1-BMS-193885
5ZBQ-Y1-UR-MK-299
Network Difference
Value npy1_on_gp npy1_off
Imin 1.24 4.235
Number of Linked Nodes 853 303
Number of Specific Nodes 587 (68.82%) 37  (12.21%)
Number of Shared Nodes 266 (31.18%) 266  (87.79%)
Number of Links 1298 309
Number of Specific Links 1148 (88.44%) 159  (51.46%)
Number of Shared Links 150 (11.56%) 150  (48.54%)
Number of Hubs 300 28
Number of Specific Hubs 284 (94.67%) 12  (42.86%)
Number of Shared Hubs 16 (5.33%) 16  (57.14%)
Average % Shared Neighbours (Jaccard) 10.26
Average % Shared Neighbours (Otsuka) 13.72
Average % Shared Neighbours (Overlap Coefficient) 17.35
Average % Shared Cliques (k3-6) 50.26
Graphlets Similarity 0.487255
Paths Difference
Value npy1_on_gp npy1_off
Number Of Nodes in MetaPath 73 55
Specific Nodes in MetaPath 65 (89.04%) 47  (85.45%)
Shared Nodes in MetaPath 266 (31.18%) 266  (31.18%)
Number Of Links MetaPath 78 55
Specific Links in MetaPath 74 (94.87%) 51  (92.73%)
Shared Links in MetaPath 150 (11.56%) 150  (11.56%)
Number of Shortest Paths 19239365 62074
Length Of Smallest Path 3 3
Average Path Length 46.954 17.0752
Length of Longest Path 59 42
Minimum Path Strength 1.24 0.77
Average Path Strength 4.19039 6.73783
Maximum Path Strength 18.905 18.935
Minimum Path Correlation 0.7 0.7
Average Path Correlation 1 0.930094
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 2.38095 2.5641
Average % Of Corr. Nodes 30.3756 47.1036
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 82.9211 31.6318
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download npy1_off_on_gp.zip<



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