psnGPCR

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Orange: nodes, hubs and links specific of npy_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of npy_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	npy_off Int. Strength	npy_on Int. Strength	npy_off Hub1?	npy_on Hub1?	npy_off Hub2?	npy_on Hub2?	ConSurf1	ConSurf2
1	NT	NT	npy_off	100	0	Yes	Yes	Yes	Yes	5	5
2	7x28	NT	npy_off	100	0	No	No	Yes	Yes	2	5
3	1x42	7x47	npy_off	100	0	No	No	Yes	No	7	8
4	1x45	7x47	npy_off	100	0	No	No	Yes	No	5	8
5	1x53	7x53	npy_off	100	0	No	Yes	Yes	Yes	9	9
6	1x57	2x40	npy_off	100	0	No	No	Yes	Yes	7	8
7	1x60	I1x50	npy_off	100	0	No	No	No	No	5	7
8	2x39	3x50	npy_off	100	0	No	No	Yes	No	7	9
9	2x40	7x53	npy_off	100	0	Yes	Yes	Yes	Yes	8	9
10	2x41	4x39	npy_off	100	0	No	No	No	No	5	2
11	2x46	3x39	npy_off	100	0	Yes	Yes	No	No	9	9
12	2x59	3x24	npy_off	100	0	No	No	No	No	6	6
13	2x60	3x28	npy_off	100	0	No	No	No	No	6	5
14	2x61	2x65	npy_off	100	0	No	No	No	No	6	4
15	2x67	E2	npy_off	100	0	No	No	Yes	Yes	4	3
16	3x30	3x34	npy_off	100	0	No	No	No	No	6	5
17	3x32	7x38	npy_off	100	0	Yes	Yes	Yes	Yes	6	6
18	3x39	6x44	npy_off	100	0	No	No	Yes	Yes	9	9
19	3x41	5x50	npy_off	100	0	Yes	No	No	No	7	9
20	3x43	6x41	npy_off	100	0	No	Yes	No	No	8	8
21	3x44	5x54	npy_off	100	0	No	No	No	No	7	8
22	3x46	6x37	npy_off	100	0	No	No	No	No	8	8
23	3x49	I2	npy_off	100	0	No	Yes	Yes	Yes	8	6
24	3x50	6x33	npy_off	100	0	Yes	No	No	No	9	7
25	3x50	6x34	npy_off	100	0	Yes	No	No	No	9	6
26	3x50	6x37	npy_off	100	0	Yes	No	No	No	9	8
27	3x51	5x61	npy_off	100	0	No	Yes	No	No	7	8
28	3x56	I2	npy_off	100	0	No	No	Yes	Yes	6	6
29	4x40	4x43	npy_off	100	0	No	No	No	No	5	3
30	4x65	E2x50	npy_off	100	0	Yes	Yes	No	No	5	9
31	5x35	E2	npy_off	100	0	No	No	Yes	Yes	3	3
32	5x33	5x36	npy_off	100	0	No	No	Yes	Yes	1	4
33	5x33	E3	npy_off	100	0	No	No	Yes	Yes	1	3
34	5x36	E3	npy_off	100	0	Yes	Yes	Yes	Yes	4	3
35	5x39	5x43	npy_off	100	0	No	Yes	No	No	6	5
36	5x44	5x48	npy_off	100	0	No	No	No	No	6	5
37	5x54	6x41	npy_off	100	0	No	No	No	No	8	8
38	5x58	6x38	npy_off	100	0	No	Yes	No	No	9	5
39	6x36	7x53	npy_off	100	0	No	No	Yes	Yes	8	9
40	6x36	8x47	npy_off	100	0	No	No	No	No	8	8
41	6x40	7x49	npy_off	100	0	No	No	No	Yes	7	9
42	6x48	7x41	npy_off	100	0	Yes	Yes	No	No	8	8
43	6x51	7x34	npy_off	100	0	No	No	No	No	7	5
44	6x52	Lig	npy_off	100	0	Yes	No	Yes	Yes	8	0
45	6x54	Lig	npy_off	100	0	Yes	Yes	Yes	Yes	5	0
46	6x58	7x30	npy_off	100	0	Yes	No	Yes	No	4	3
47	7x27	7x30	npy_off	100	0	No	No	Yes	No	1	3
48	8x50	8x54	npy_off	100	0	Yes	Yes	No	No	8	5
49	E2	NT	npy_off	100	0	Yes	Yes	Yes	Yes	3	5
50	4x65	Lig	npy_off	100	0	Yes	Yes	Yes	Yes	5	0
51	1x52	8x54	npy_off	100	0	No	No	No	No	6	5
52	8x50	I1x50	npy_off	100	0	Yes	Yes	No	No	8	7
53	3x54	6x30	npy_off	100	0	No	No	No	Yes	8	7
54	6x30	I2	npy_off	100	0	No	Yes	Yes	Yes	7	6
55	5x68	6x27	npy_off	100	0	No	No	No	No	6	4
56	6x27	6x31	npy_off	100	0	No	No	No	No	4	6
57	7x55	7x56	npy_off	100	0	No	No	No	No	6	6
58	5x59	5x63	npy_off	50	0	No	No	No	No	4	3
59	6x34	6x35	npy_off	50	0	No	No	No	No	6	6
60	3x30	4x54	npy_off	50	0	No	No	No	No	6	4
61	2x53	3x32	npy_off	50	0	No	Yes	Yes	Yes	7	6
62	5x53	5x57	npy_off	50	0	No	No	No	No	6	7
63	6x26	I2	npy_off	50	0	No	Yes	Yes	Yes	4	6
64	8x57	8x58	npy_off	50	0	No	No	No	No	5	5
65	6x28	6x32	npy_off	50	0	No	No	No	No	4	7
66	1x43	2x58	npy_off	25	0	No	No	No	No	7	8
67	2x37	I1x49	npy_off	50	0	No	No	No	No	8	5
68	3x41	5x461	npy_off	50	0	Yes	No	No	Yes	7	6
69	6x39	7x56	npy_off	50	0	No	No	No	No	5	6
70	5x34	5x35	npy_off	75	0	No	No	No	No	1	3
71	3x44	5x53	npy_off	0	0	No	No	No	No	7	6
72	1x54	2x47	npy_off	50	0	No	No	No	No	7	9
73	5x62	5x63	npy_off	50	0	No	No	No	No	5	3
74	1x54	2x48	npy_off	50	0	No	No	No	No	7	6
75	5x61	6x34	npy_off	25	0	No	No	No	No	8	6
76	5x62	6x35	npy_off	50	0	No	No	No	No	5	6
77	4x48	4x52	npy_off	50	0	No	No	No	No	4	5
78	3x54	5x65	npy_off	0	0	No	No	No	No	8	8
79	1x51	2x51	npy_off	25	0	No	No	No	No	4	8
80	3x48	5x53	npy_off	0	0	No	No	No	No	6	6
81	2x38	4x39	npy_off	0	0	No	No	No	No	6	2
82	2x56	3x31	npy_off	0	0	No	No	No	No	7	5
83	6x29	6x32	npy_off	50	0	No	No	No	No	6	7
84	6x43	7x48	npy_off	25	0	No	No	No	No	7	6
85	5x45	5x46	npy_off	50	0	No	No	No	No	5	5
86	7x32	7x35	npy_off	50	0	No	No	No	No	2	4
87	2x64	7x31	npy_off	50	0	No	No	No	No	4	4
88	7x27	7x29	npy_off	50	0	No	No	No	No	1	3
89	4x39	I1x48	npy_off	50	0	No	No	No	No	2	6
90	2x61	7x35	npy_off	50	0	No	No	No	No	6	4
91	6x26	6x29	npy_off	50	0	No	Yes	No	No	4	6
92	3x26	4x65	npy_off	0	0	No	No	Yes	Yes	7	5
93	3x21	3x22	npy_off	50	0	No	No	No	No	8	3
94	1x60	8x56	npy_off	50	0	No	No	No	No	5	4
95	1x31	7x32	npy_off	25	0	No	No	No	No	4	2
96	1x35	1x39	npy_off	25	0	No	No	Yes	Yes	7	7
97	6x22	6x25	npy_off	25	0	No	No	No	No	3	3
98	7x26	7x30	npy_off	50	0	No	No	Yes	No	0	3
99	1x47	2x54	npy_off	0	0	No	No	No	No	7	7
100	6x24	6x27	npy_off	25	0	No	No	No	No	2	4
101	7x54	8x50	npy_off	25	0	No	No	Yes	Yes	7	8
102	7x54	8x54	npy_off	0	0	No	No	No	No	7	5
103	1x30	1x33	npy_off	0	0	No	No	No	No	2	6
104	5x42	5x46	npy_off	25	0	No	No	No	No	4	5
105	8x56	8x59	npy_off	0	0	No	No	No	No	4	0
106	5x36	5x37	npy_off	0	0	Yes	Yes	No	No	4	3
107	1x37	1x40	npy_off	0	0	No	No	No	No	5	5
108	3x23	3x24	npy_off	0	0	No	No	No	No	1	6
109	3x23	3x27	npy_off	0	0	No	No	No	No	1	5
110	6x57	6x58	npy_off	0	0	No	No	Yes	No	4	4
111	8x55	CT	npy_off	0	0	No	No	No	No	4	4
112	1x28	1x31	Shared	100	100	No	No	No	No	4	4
113	1x32	2x65	Shared	100	33.3333	No	No	No	No	3	4
114	1x33	1x37	Shared	100	100	No	No	No	No	6	5
115	1x39	2x57	Shared	100	100	Yes	Yes	No	Yes	7	7
116	1x39	2x61	Shared	100	100	Yes	Yes	No	No	7	6
117	1x39	7x38	Shared	100	100	Yes	Yes	Yes	Yes	7	6
118	1x39	7x39	Shared	100	100	Yes	Yes	No	No	7	5
119	1x43	2x57	Shared	100	100	No	No	No	Yes	7	7
120	1x49	7x50	Shared	100	33.3333	No	No	No	No	8	9
121	1x50	2x47	Shared	100	100	No	Yes	No	No	9	9
122	1x50	2x50	Shared	100	100	No	Yes	No	Yes	9	9
123	1x50	7x50	Shared	100	100	No	Yes	No	No	9	9
124	1x57	2x44	Shared	100	33.3333	No	No	No	No	7	5
125	I1x48	I1x51	Shared	100	33.3333	No	No	No	Yes	6	6
126	2x37	2x40	Shared	100	100	No	No	Yes	Yes	8	8
127	2x38	3x49	Shared	100	100	No	No	No	Yes	6	8
128	2x41	4x43	Shared	100	100	No	No	No	No	5	3
129	2x42	3x45	Shared	100	100	No	Yes	No	No	7	7
130	2x42	3x46	Shared	100	100	No	Yes	No	No	7	8
131	2x43	7x53	Shared	100	100	No	No	Yes	Yes	8	9
132	2x45	3x42	Shared	100	100	No	No	No	No	9	8
133	2x45	4x46	Shared	100	100	No	No	No	Yes	9	7
134	2x45	4x50	Shared	100	100	No	No	No	Yes	9	9
135	2x46	3x43	Shared	100	100	Yes	Yes	No	Yes	9	8
136	2x50	7x46	Shared	100	100	No	Yes	No	No	9	8
137	2x56	3x32	Shared	100	100	No	No	Yes	Yes	7	6
138	2x57	7x42	Shared	100	100	No	Yes	No	Yes	7	7
139	2x59	E1x52	Shared	100	100	No	No	Yes	Yes	6	7
140	2x60	7x38	Shared	100	100	No	No	Yes	Yes	6	6
141	2x63	E1x50	Shared	100	100	No	No	Yes	Yes	6	8
142	2x64	7x35	Shared	100	100	No	No	No	No	4	4
143	2x66	E1x51	Shared	100	100	No	No	No	No	3	2
144	E1x49	E2	Shared	100	100	No	No	Yes	Yes	5	3
145	E1x50	E1x52	Shared	100	100	Yes	Yes	Yes	Yes	8	7
146	3x25	E1x50	Shared	100	100	No	No	Yes	Yes	9	8
147	E1x50	E2x50	Shared	100	100	Yes	Yes	No	No	8	9
148	3x22	E2	Shared	100	100	No	No	Yes	Yes	3	3
149	3x25	E2	Shared	100	100	No	No	Yes	Yes	9	3
150	3x25	E2x50	Shared	100	100	No	No	No	No	9	9
151	3x29	4x65	Shared	100	100	No	No	Yes	Yes	6	5
152	3x30	4x62	Shared	100	100	No	No	No	No	6	5
153	3x32	Lig	Shared	100	100	Yes	Yes	Yes	Yes	6	0
154	3x33	4x57	Shared	100	100	No	No	No	No	4	7
155	3x34	4x50	Shared	100	100	No	No	No	Yes	5	9
156	3x36	6x48	Shared	100	100	No	No	Yes	Yes	7	8
157	3x36	Lig	Shared	100	100	No	No	Yes	Yes	7	0
158	3x37	4x53	Shared	100	100	No	No	No	No	6	8
159	3x37	5x461	Shared	100	100	No	No	No	Yes	6	6
160	3x38	4x50	Shared	100	100	No	No	No	Yes	7	9
161	3x40	5x50	Shared	100	100	No	No	No	No	7	9
162	3x40	6x44	Shared	100	100	No	No	Yes	Yes	7	9
163	3x41	4x49	Shared	100	100	Yes	No	No	No	7	7
164	3x43	6x44	Shared	100	100	No	Yes	Yes	Yes	8	9
165	3x47	5x54	Shared	100	100	No	No	No	No	9	8
166	3x47	5x58	Shared	100	100	No	No	No	Yes	9	9
167	3x49	3x53	Shared	100	100	No	Yes	No	No	8	8
168	3x51	3x55	Shared	100	100	No	Yes	No	No	7	6
169	3x51	5x60	Shared	100	100	No	Yes	No	No	7	4
170	3x52	3x56	Shared	100	100	No	No	No	No	4	6
171	3x52	I2	Shared	100	100	No	No	Yes	Yes	4	6
172	3x55	5x64	Shared	100	100	No	No	No	Yes	6	5
173	I2	I2	Shared	100	100	Yes	Yes	Yes	Yes	6	6
174	4x38	4x40	Shared	100	100	No	No	No	No	7	5
175	4x60	5x39	Shared	100	100	No	No	No	Yes	8	6
176	4x61	5x39	Shared	100	100	No	Yes	No	Yes	5	6
177	4x61	Lig	Shared	100	100	No	Yes	Yes	Yes	5	0
178	4x63	4x64	Shared	100	100	No	No	No	No	4	5
179	4x64	E2	Shared	100	100	No	No	Yes	Yes	5	3
180	4x65	E2x52	Shared	100	100	Yes	Yes	No	Yes	5	4
181	E2	E2	Shared	100	100	Yes	Yes	Yes	Yes	3	3
182	E2	E2x51	Shared	100	100	Yes	Yes	No	No	3	3
183	5x36	E2	Shared	100	100	Yes	Yes	Yes	Yes	4	3
184	5x32	5x35	Shared	100	100	No	No	No	No	3	3
185	5x37	6x60	Shared	100	100	No	No	No	No	3	4
186	5x40	6x59	Shared	100	100	No	No	No	Yes	5	4
187	5x40	Lig	Shared	100	100	No	No	Yes	Yes	5	0
188	5x44	6x52	Shared	100	33.3333	No	No	Yes	No	6	8
189	5x47	5x48	Shared	100	33.3333	Yes	Yes	No	No	8	5
190	5x47	5x51	Shared	100	100	Yes	Yes	No	No	8	6
191	5x47	6x49	Shared	100	100	Yes	Yes	No	No	8	6
192	5x47	6x52	Shared	100	100	Yes	Yes	Yes	No	8	8
193	5x49	5x50	Shared	100	100	No	No	No	No	5	9
194	5x51	6x45	Shared	100	100	No	No	No	No	6	6
195	5x56	5x60	Shared	100	100	No	No	No	No	4	4
196	5x58	6x37	Shared	100	100	No	Yes	No	No	9	8
197	5x62	5x66	Shared	100	100	No	No	No	No	5	4
198	6x32	8x48	Shared	100	33.3333	No	No	No	No	7	5
199	6x36	7x56	Shared	100	100	No	No	No	No	8	6
200	6x40	7x52	Shared	100	100	No	No	No	Yes	7	8
201	6x44	6x48	Shared	100	100	Yes	Yes	Yes	Yes	9	8
202	6x48	6x52	Shared	100	100	Yes	Yes	Yes	No	8	8
203	6x48	7x45	Shared	100	100	Yes	Yes	No	No	8	9
204	6x50	7x37	Shared	100	100	No	No	No	No	9	6
205	6x50	7x40	Shared	100	100	No	No	No	No	9	7
206	6x51	6x55	Shared	100	100	No	No	No	No	7	5
207	6x54	6x58	Shared	100	100	Yes	Yes	Yes	No	5	4
208	6x54	7x33	Shared	100	100	Yes	Yes	No	No	5	6
209	6x54	7x34	Shared	100	100	Yes	Yes	No	No	5	5
210	6x54	7x37	Shared	100	100	Yes	Yes	No	No	5	6
211	6x55	Lig	Shared	100	100	No	No	Yes	Yes	5	0
212	6x58	Lig	Shared	100	100	Yes	No	Yes	Yes	4	0
213	6x59	Lig	Shared	100	100	No	Yes	Yes	Yes	4	0
214	6x61	E3	Shared	100	100	No	No	Yes	Yes	4	3
215	7x30	E3	Shared	100	100	Yes	No	Yes	Yes	3	3
216	7x34	Lig	Shared	100	100	No	No	Yes	Yes	5	0
217	7x38	7x42	Shared	100	100	Yes	Yes	No	Yes	6	7
218	8x47	8x50	Shared	100	100	No	No	Yes	Yes	8	8
219	8x48	8x51	Shared	100	33.3333	No	No	No	No	5	8
220	7x38	Lig	Shared	100	100	Yes	Yes	Yes	Yes	6	0
221	1x44	1x48	Shared	100	33.3333	No	No	No	No	5	5
222	6x54	7x30	Shared	100	100	Yes	Yes	Yes	No	5	3
223	8x48	8x52	Shared	100	100	No	No	No	No	5	5
224	2x60	Lig	Shared	100	100	No	No	Yes	Yes	6	0
225	1x36	2x65	Shared	100	33.3333	No	No	No	No	5	4
226	1x52	8x58	Shared	100	33.3333	No	No	No	No	6	5
227	2x40	8x50	Shared	100	100	Yes	Yes	Yes	Yes	8	8
228	2x54	7x46	Shared	100	100	No	No	No	No	7	8
229	2x46	7x49	Shared	50	100	Yes	Yes	No	Yes	9	9
230	1x56	8x50	Shared	50	100	No	No	Yes	Yes	7	8
231	2x46	3x42	Shared	50	100	Yes	Yes	No	No	9	8
232	2x49	3x38	Shared	50	100	No	No	No	No	8	7
233	2x53	3x35	Shared	50	100	No	Yes	No	No	7	8
234	E1x51	E1x52	Shared	50	100	No	No	Yes	Yes	2	7
235	3x55	3x56	Shared	75	100	No	No	No	No	6	6
236	3x33	4x61	Shared	50	100	No	No	No	Yes	4	5
237	1x56	8x53	Shared	75	100	No	No	No	No	7	5
238	1x53	2x47	Shared	25	100	No	Yes	No	No	9	9
239	4x59	4x60	Shared	50	100	No	No	No	No	4	8
240	7x43	7x47	Shared	50	100	No	No	Yes	No	6	8
241	2x62	E1x52	Shared	25	100	No	No	Yes	Yes	4	7
242	2x38	4x42	Shared	50	100	No	No	No	No	6	7
243	4x38	4x41	Shared	50	0	No	No	No	No	7	4
244	2x551	3x31	Shared	50	100	No	No	No	No	5	5
245	6x47	7x45	Shared	50	100	No	No	No	No	8	9
246	2x50	3x39	Shared	50	100	No	Yes	No	No	9	9
247	1x59	1x60	Shared	25	33.3333	No	No	No	No	5	5
248	6x25	6x29	Shared	50	100	No	No	No	No	3	6
249	3x37	4x56	Shared	50	100	No	No	No	No	6	5
250	3x41	4x52	Shared	25	0	Yes	No	No	No	7	5
251	7x48	7x52	Shared	50	33.3333	No	No	No	Yes	6	8
252	6x47	7x43	Shared	0	33.3333	No	No	No	No	8	6
253	5x64	5x68	Shared	50	100	No	Yes	No	No	5	6
254	3x45	4x45	Shared	0	33.3333	No	No	No	No	7	5
255	1x38	7x39	Shared	0	0	No	No	No	No	6	5
256	1x48	1x49	Shared	0	100	No	No	No	No	5	8
257	2x51	2x55	Shared	0	33.3333	No	No	No	No	8	5
258	1x54	1x58	Shared	0	100	No	No	No	No	7	4
259	1x40	1x43	Shared	25	33.3333	No	No	No	No	5	7
260	5x64	5x67	Shared	50	100	No	Yes	No	No	5	4
261	2x48	2x52	Shared	50	100	No	No	No	No	6	7
262	5x41	6x60	Shared	50	33.3333	No	No	No	No	5	4
263	8x47	8x49	Shared	0	100	No	No	No	No	8	6
264	5x55	6x41	Shared	0	0	No	No	No	No	5	8
265	1x55	1x59	Shared	50	100	No	No	No	No	3	5
266	7x51	7x55	Shared	25	100	No	No	No	No	6	6
267	3x27	3x31	Shared	25	0	No	No	No	No	5	5
268	5x45	5x48	Shared	0	100	No	No	No	No	5	5
269	4x44	4x48	Shared	0	100	No	No	No	No	3	4
270	6x49	6x53	Shared	25	0	No	No	No	No	6	5
271	1x46	7x47	Shared	0	33.3333	No	No	Yes	No	7	8
272	7x32	7x36	Shared	0	0	No	No	No	No	2	6
273	6x42	6x46	Shared	0	0	No	No	No	No	5	6
274	1x47	2x51	Shared	0	100	No	No	No	No	7	8
275	1x29	1x32	Shared	25	0	No	No	No	No	3	3
276	5x44	6x56	Shared	0	100	No	No	No	No	6	6
277	6x38	6x42	Shared	0	0	No	No	No	No	5	5
278	8x58	CT	Shared	0	0	No	No	No	No	5	4
279	5x38	5x42	Shared	0	33.3333	No	No	No	No	4	4
280	1x34	1x35	Shared	0	0	No	No	No	No	5	7
281	1x32	NT	npy_on	0	100	No	No	Yes	Yes	3	5
282	1x30	1x31	npy_on	0	100	No	No	No	No	2	4
283	1x35	7x35	npy_on	0	100	No	No	No	No	7	4
284	1x39	7x35	npy_on	0	100	Yes	Yes	No	No	7	4
285	1x42	2x57	npy_on	0	100	No	No	No	Yes	7	7
286	1x42	7x39	npy_on	0	100	No	No	No	No	7	5
287	1x50	2x51	npy_on	0	100	No	Yes	No	No	9	8
288	1x53	1x57	npy_on	0	100	No	Yes	No	No	9	7
289	1x53	2x43	npy_on	0	100	No	Yes	No	No	9	8
290	1x56	8x54	npy_on	0	100	No	No	No	No	7	5
291	1x57	8x50	npy_on	0	100	No	No	Yes	Yes	7	8
292	1x60	8x50	npy_on	0	100	No	No	Yes	Yes	5	8
293	I1x49	I1x51	npy_on	0	100	No	No	No	Yes	5	6
294	2x39	3x49	npy_on	0	100	No	No	No	Yes	7	8
295	2x42	3x49	npy_on	0	100	No	Yes	No	Yes	7	8
296	2x42	4x46	npy_on	0	100	No	Yes	No	Yes	7	7
297	2x46	2x50	npy_on	0	100	Yes	Yes	No	Yes	9	9
298	2x46	7x53	npy_on	0	100	Yes	Yes	Yes	Yes	9	9
299	2x49	3x39	npy_on	0	100	No	No	No	No	8	9
300	2x50	7x49	npy_on	0	100	No	Yes	No	Yes	9	9
301	2x52	3x35	npy_on	0	100	No	No	No	No	7	8
302	2x53	2x56	npy_on	0	100	No	Yes	No	No	7	7
303	2x53	3x36	npy_on	0	100	No	Yes	No	No	7	7
304	2x54	2x57	npy_on	0	100	No	No	No	Yes	7	7
305	2x55	2x551	npy_on	0	100	No	No	No	No	5	5
306	2x56	7x42	npy_on	0	100	No	No	No	Yes	7	7
307	2x57	2x58	npy_on	0	100	No	Yes	No	No	7	8
308	2x59	3x28	npy_on	0	100	No	No	No	No	6	5
309	2x60	3x32	npy_on	0	100	No	No	Yes	Yes	6	6
310	2x63	Lig	npy_on	0	100	No	No	Yes	Yes	6	0
311	2x66	E1x49	npy_on	0	100	No	No	No	No	3	5
312	2x67	Lig	npy_on	0	100	No	No	Yes	Yes	4	0
313	E1x49	E1x51	npy_on	0	100	No	No	No	No	5	2
314	E1x50	E2	npy_on	0	100	Yes	Yes	Yes	Yes	8	3
315	3x24	E1x52	npy_on	0	100	No	No	Yes	Yes	6	7
316	3x22	3x26	npy_on	0	100	No	No	No	No	3	7
317	3x28	3x32	npy_on	0	100	No	No	Yes	Yes	5	6
318	3x30	4x57	npy_on	0	100	No	No	No	No	6	7
319	3x34	4x57	npy_on	0	100	No	No	No	No	5	7
320	3x40	6x48	npy_on	0	100	No	No	Yes	Yes	7	8
321	3x43	7x49	npy_on	0	100	No	Yes	No	Yes	8	9
322	3x43	7x53	npy_on	0	100	No	Yes	Yes	Yes	8	9
323	3x44	5x50	npy_on	0	100	No	No	No	No	7	9
324	3x45	4x49	npy_on	0	100	No	No	No	No	7	7
325	3x46	3x50	npy_on	0	100	No	No	Yes	No	8	9
326	3x46	7x53	npy_on	0	100	No	No	Yes	Yes	8	9
327	3x50	5x58	npy_on	0	100	Yes	No	No	Yes	9	9
328	3x50	7x53	npy_on	0	100	Yes	No	Yes	Yes	9	9
329	3x51	5x57	npy_on	0	100	No	Yes	No	No	7	7
330	3x53	I2	npy_on	0	100	No	No	Yes	Yes	8	6
331	5x64	I2	npy_on	0	100	No	Yes	Yes	Yes	5	6
332	4x41	I2	npy_on	0	100	No	No	Yes	Yes	4	6
333	4x39	4x43	npy_on	0	100	No	No	No	No	2	3
334	4x46	4x50	npy_on	0	100	No	Yes	No	Yes	7	9
335	4x59	4x63	npy_on	0	100	No	No	No	No	4	4
336	E2	E2x50	npy_on	0	100	Yes	Yes	No	No	3	9
337	E2	Lig	npy_on	0	100	Yes	Yes	Yes	Yes	3	0
338	E2x51	Lig	npy_on	0	100	No	No	Yes	Yes	3	0
339	E2	E2x52	npy_on	0	100	Yes	Yes	No	Yes	3	4
340	5x39	E2	npy_on	0	100	No	Yes	Yes	Yes	6	3
341	5x36	6x59	npy_on	0	100	Yes	Yes	No	Yes	4	4
342	5x36	Lig	npy_on	0	100	Yes	Yes	Yes	Yes	4	0
343	5x43	5x461	npy_on	0	100	No	No	No	Yes	5	6
344	5x43	Lig	npy_on	0	100	No	No	Yes	Yes	5	0
345	5x461	Lig	npy_on	0	100	No	Yes	Yes	Yes	6	0
346	5x51	6x44	npy_on	0	100	No	No	Yes	Yes	6	9
347	5x54	5x58	npy_on	0	100	No	No	No	Yes	8	9
348	5x58	6x40	npy_on	0	100	No	Yes	No	No	9	7
349	5x58	6x41	npy_on	0	100	No	Yes	No	No	9	8
350	5x62	6x34	npy_on	0	100	No	No	No	No	5	6
351	5x65	5x69	npy_on	0	100	No	No	No	No	8	0
352	5x66	5x70	npy_on	0	100	No	No	No	No	4	0
353	5x70	6x30	npy_on	0	100	No	No	No	Yes	0	7
354	6x23	6x26	npy_on	0	100	No	No	No	Yes	3	4
355	6x27	6x30	npy_on	0	100	No	No	No	Yes	4	7
356	6x31	6x35	npy_on	0	100	No	No	No	No	6	6
357	6x40	7x53	npy_on	0	100	No	No	Yes	Yes	7	9
358	6x49	6x50	npy_on	0	100	No	No	No	No	6	9
359	6x51	7x41	npy_on	0	100	No	No	No	No	7	8
360	6x58	6x59	npy_on	0	100	Yes	No	No	Yes	4	4
361	7x30	Lig	npy_on	0	100	Yes	No	Yes	Yes	3	0
362	7x31	Lig	npy_on	0	100	No	No	Yes	Yes	4	0
363	7x49	7x53	npy_on	0	100	No	Yes	Yes	Yes	9	9
364	7x55	8x51	npy_on	0	100	No	No	No	No	6	8
365	7x55	8x54	npy_on	0	100	No	No	No	No	6	5
366	8x49	8x50	npy_on	0	100	No	No	Yes	Yes	6	8
367	8x55	8x56	npy_on	0	100	No	No	No	No	4	4
368	Lig	Lig	npy_on	0	100	Yes	Yes	Yes	Yes	0	0
369	Lig	NT	npy_on	0	100	Yes	Yes	Yes	Yes	0	5
370	E3	Lig	npy_on	0	100	Yes	Yes	Yes	Yes	3	0
371	E2x52	Lig	npy_on	0	100	No	Yes	Yes	Yes	4	0
372	2x64	Lig	npy_on	0	100	No	No	Yes	Yes	4	0
373	5x39	Lig	npy_on	0	100	No	Yes	Yes	Yes	6	0
374	7x29	NT	npy_on	0	100	No	No	Yes	Yes	3	5
375	2x39	2x40	npy_on	0	100	No	No	Yes	Yes	7	8
376	2x43	8x50	npy_on	0	100	No	No	Yes	Yes	8	8
377	2x53	7x42	npy_on	0	100	No	Yes	No	Yes	7	7
378	2x63	E2	npy_on	0	100	No	No	Yes	Yes	6	3
379	3x28	E1x50	npy_on	0	100	No	No	Yes	Yes	5	8
380	3x51	3x56	npy_on	0	100	No	Yes	No	No	7	6
381	3x54	5x61	npy_on	0	100	No	No	No	No	8	8
382	5x49	5x53	npy_on	0	100	No	No	No	No	5	6
383	5x66	6x30	npy_on	0	100	No	No	No	Yes	4	7
384	6x26	6x27	npy_on	0	100	No	Yes	No	No	4	4
385	6x26	6x30	npy_on	0	100	No	Yes	No	Yes	4	7
386	7x52	7x53	npy_on	0	100	No	Yes	Yes	Yes	8	9
387	8x55	8x59	npy_on	0	100	No	No	No	No	4	0
388	4x61	4x65	npy_on	0	100	No	Yes	Yes	Yes	5	5
389	4x65	E2	npy_on	0	100	Yes	Yes	Yes	Yes	5	3
390	5x36	E2x52	npy_on	0	100	Yes	Yes	No	Yes	4	4
391	5x54	6x44	npy_on	0	100	No	No	Yes	Yes	8	9
392	5x71	5x72	npy_on	0	100	No	No	No	No	0	0
393	6x26	I3	npy_on	0	100	No	Yes	No	No	4	0
394	E3	E3	npy_on	0	100	Yes	Yes	Yes	Yes	3	3
395	6x32	6x36	npy_on	0	66.6667	No	No	No	No	7	8
396	5x65	6x30	npy_on	0	33.3333	No	No	No	Yes	8	7
397	7x29	7x32	npy_on	0	33.3333	No	No	No	No	3	2
398	7x27	Lig	npy_on	0	33.3333	No	No	Yes	Yes	1	0
399	5x68	6x26	npy_on	0	33.3333	No	No	No	Yes	6	4
400	1x54	2x44	npy_on	0	33.3333	No	No	No	No	7	5
401	1x52	8x53	npy_on	0	33.3333	No	No	No	No	6	5
402	5x58	5x61	npy_on	0	66.6667	No	Yes	No	No	9	8
403	2x37	I1x51	npy_on	0	33.3333	No	No	No	Yes	8	6
404	6x43	7x52	npy_on	0	33.3333	No	No	No	Yes	7	8
405	5x65	6x33	npy_on	0	0	No	No	No	No	8	7
406	2x40	I1x50	npy_on	0	33.3333	Yes	Yes	No	No	8	7
407	7x28	7x29	npy_on	0	33.3333	No	No	No	No	2	3
408	5x46	5x461	npy_on	0	66.6667	No	No	No	Yes	5	6
409	1x45	1x46	npy_on	0	33.3333	No	No	No	No	5	7
410	6x24	6x28	npy_on	0	33.3333	No	No	No	No	2	4
411	5x70	5x71	npy_on	0	33.3333	No	No	No	No	0	0
412	3x34	4x54	npy_on	0	0	No	No	No	No	5	4
413	3x21	E1x52	npy_on	0	33.3333	No	No	Yes	Yes	8	7
414	6x30	6x31	npy_on	0	33.3333	No	Yes	No	No	7	6
415	3x44	3x48	npy_on	0	0	No	No	No	No	7	6
416	2x41	I1x51	npy_on	0	33.3333	No	No	No	Yes	5	6
417	1x31	NT	npy_on	0	33.3333	No	No	Yes	Yes	4	5
418	5x73	I3	npy_on	0	33.3333	No	No	No	No	0	0
419	6x22	I3	npy_on	0	33.3333	No	No	No	No	3	0
420	5x63	5x67	npy_on	0	33.3333	No	No	No	No	3	4
421	5x35	5x38	npy_on	0	33.3333	No	No	No	No	3	4
422	5x42	5x45	npy_on	0	33.3333	No	No	No	No	4	5
423	8x53	8x56	npy_on	0	33.3333	No	No	No	No	5	4
424	4x44	4x45	npy_on	0	0	No	No	No	No	3	5
425	4x45	4x48	npy_on	0	0	No	No	No	No	5	4
426	1x53	7x54	npy_on	0	0	No	Yes	No	No	9	7
427	5x32	5x34	npy_on	0	33.3333	No	No	No	No	3	1
428	6x39	7x52	npy_on	0	33.3333	No	No	No	Yes	5	8
429	5x33	E2	npy_on	0	33.3333	No	No	Yes	Yes	1	3
430	6x25	6x26	npy_on	0	33.3333	No	No	No	Yes	3	4
431	5x34	5x37	npy_on	0	33.3333	No	No	No	No	1	3
432	3x23	3x26	npy_on	0	0	No	No	No	No	1	7
433	1x47	1x51	npy_on	0	0	No	No	No	No	7	4
434	6x28	6x29	npy_on	0	33.3333	No	No	No	No	4	6
435	4x52	4x56	npy_on	0	33.3333	No	No	No	No	5	5
436	8x54	8x57	npy_on	0	0	No	No	No	No	5	5
437	7x26	7x27	npy_on	0	33.3333	No	No	No	No	0	1
438	5x59	5x62	npy_on	0	33.3333	No	No	No	No	4	5
439	4x46	4x47	npy_on	0	33.3333	No	Yes	No	No	7	4
440	6x46	6x47	npy_on	0	0	No	No	No	No	6	8
441	1x33	1x34	npy_on	0	0	No	No	No	No	6	5
442	6x38	6x41	npy_on	0	0	No	No	No	No	5	8
443	6x39	6x42	npy_on	0	0	No	No	No	No	5	5
444	4x54	4x55	npy_on	0	0	No	No	No	No	4	3
445	6x57	E3	npy_on	0	0	No	No	Yes	Yes	4	3
446	1x41	1x45	npy_on	0	0	No	No	No	No	5	5
447	4x48	4x51	npy_on	0	0	No	No	No	No	4	4
448	1x29	1x30	npy_on	0	0	No	No	No	No	3	2

Orange: nodes, hubs and links specific of npy_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of npy_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	npy_off Avg Int. Strength	npy_on Avg Int. Strength	npy_off Num Of Links	npy_on Num Of Links	ConSurf
1	3x41	npy_off	25	0	4	2	7
2	3x50	npy_off	0	0	4	3	9
3	6x52	npy_off	50	33.3333	4	3	8
4	6x58	npy_off	25	0	4	3	4
5	7x30	npy_off	50	33.3333	5	3	3
6	7x47	npy_off	0	0	4	2	8
7	NT	Shared	50	33.3333	4	4	5
8	1x39	Shared	75	66.6667	5	5	7
9	2x40	Shared	0	33.3333	4	4	8
10	2x46	Shared	0	100	4	5	9
11	E1x50	Shared	100	100	4	6	8
12	E1x52	Shared	0	66.6667	4	6	7
13	3x32	Shared	0	66.6667	4	4	6
14	I2	Shared	75	66.6667	7	6	6
15	4x65	Shared	50	0	5	4	5
16	E2	Shared	100	100	11	16	3
17	5x36	Shared	0	33.3333	4	4	4
18	5x47	Shared	50	33.3333	4	4	8
19	6x44	Shared	50	33.3333	4	5	9
20	6x48	Shared	100	100	5	5	8
21	6x54	Shared	100	100	6	5	5
22	E3	Shared	50	66.6667	4	6	3
23	7x38	Shared	75	66.6667	5	4	6
24	7x53	Shared	100	66.6667	4	8	9
25	8x50	Shared	75	100	6	7	8
26	Lig	Shared	100	100	13	27	0
27	1x50	npy_on	0	66.6667	3	4	9
28	1x53	npy_on	0	0	2	4	9
29	I1x51	npy_on	0	0	1	4	6
30	2x42	npy_on	50	33.3333	2	4	7
31	2x50	npy_on	0	100	3	5	9
32	2x53	npy_on	0	33.3333	2	4	7
33	2x57	npy_on	0	66.6667	3	6	7
34	3x43	npy_on	0	66.6667	3	4	8
35	3x49	npy_on	25	33.3333	3	4	8
36	3x51	npy_on	50	33.3333	3	4	7
37	4x46	npy_on	0	33.3333	1	4	7
38	4x50	npy_on	0	66.6667	3	4	9
39	4x61	npy_on	50	33.3333	3	4	5
40	E2x52	npy_on	0	0	1	4	4
41	5x39	npy_on	100	0	3	4	6
42	5x461	npy_on	0	66.6667	2	4	6
43	5x58	npy_on	0	100	3	7	9
44	5x64	npy_on	0	0	3	4	5
45	6x26	npy_on	0	33.3333	2	6	4
46	6x30	npy_on	50	33.3333	2	6	7
47	6x59	npy_on	0	66.6667	2	4	4
48	7x42	npy_on	0	33.3333	2	4	7
49	7x49	npy_on	0	33.3333	2	4	9
50	7x52	npy_on	0	0	2	5	8

Orange: nodes, hubs and links specific of npy_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of npy_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	npy_off Recurrence	npy_on Recurrence	npy_off Hub1?	npy_on Hub1?	npy_off Hub2?	npy_on Hub2?	ConSurf1	ConSurf2
1	1x39	2x61	npy_off	13.1553	2.4269	Yes	Yes	No	No	7	6
2	4x65	Lig	npy_off	27.255	0	Yes	Yes	Yes	Yes	5	0
3	4x65	E2x50	npy_off	23.3099	0	Yes	Yes	No	No	5	9
4	3x25	E2x50	npy_off	14.0295	0	No	No	No	No	9	9
5	3x25	E2	npy_off	13.5411	2.7076	No	No	Yes	Yes	9	3
6	1x43	2x57	npy_off	13.3883	6.23977	No	No	No	Yes	7	7
7	6x52	Lig	npy_off	52.2155	0	Yes	No	Yes	Yes	8	0
8	2x50	3x39	npy_off	49.0469	7.18713	No	Yes	No	No	9	9
9	3x39	6x44	npy_off	50.898	0	No	No	Yes	Yes	9	9
10	1x50	2x47	npy_off	37.6249	8.84211	No	Yes	No	No	9	9
11	1x53	2x47	npy_off	32.6529	8.35673	No	Yes	No	No	9	9
12	2x40	7x53	npy_off	22.3155	0	Yes	Yes	Yes	Yes	8	9
13	1x53	7x53	npy_off	31.6359	0	No	Yes	Yes	Yes	9	9
14	2x38	3x49	npy_off	10.7983	5.19883	No	No	No	Yes	6	8
15	3x49	I2	npy_off	12.9349	0	No	Yes	Yes	Yes	8	6
16	3x56	I2	npy_off	25.7721	0	No	No	Yes	Yes	6	6
17	3x55	3x56	npy_off	27.8186	0.163743	No	No	No	No	6	6
18	3x51	5x61	npy_off	37.2893	0	No	Yes	No	No	7	8
19	5x61	6x34	npy_off	38.2186	0	No	No	No	No	8	6
20	3x50	6x34	npy_off	43.7167	0	Yes	No	No	No	9	6
21	3x50	6x37	npy_off	45.951	0	Yes	No	No	No	9	8
22	5x58	6x37	npy_off	50.3619	2.46199	No	Yes	No	No	9	8
23	3x47	5x58	npy_off	53.786	1.46199	No	No	No	Yes	9	9
24	3x47	5x54	npy_off	54.6252	1.06433	No	No	No	No	9	8
25	5x54	6x41	npy_off	58.5853	0	No	No	No	No	8	8
26	3x43	6x41	npy_off	60.1984	0	No	Yes	No	No	8	8
27	2x45	3x42	npy_off	14.8536	6	No	No	No	No	9	8
28	2x46	3x42	npy_off	16.4792	6.90058	Yes	Yes	No	No	9	8
29	2x46	3x39	npy_off	20.6272	0	Yes	Yes	No	No	9	9
30	2x45	4x50	npy_off	11.5873	4.76023	No	No	No	Yes	9	9
31	3x40	5x50	npy_off	11.1289	9.84795	No	No	No	No	7	9
32	3x40	6x44	npy_off	12.1108	6.69591	No	No	Yes	Yes	7	9
33	6x54	7x30	npy_off	11.432	7.62573	Yes	Yes	Yes	No	5	3
34	7x30	E3	npy_off	14.6657	0.128655	Yes	No	Yes	Yes	3	3
35	6x58	7x30	npy_off	11.1364	0	Yes	No	Yes	No	4	3
36	6x54	Lig	npy_off	16.2287	0	Yes	Yes	Yes	Yes	5	0
37	6x58	Lig	npy_off	13.0752	9.36842	Yes	No	Yes	Yes	4	0
38	1x39	7x38	Shared	25.8823	15.4971	Yes	Yes	Yes	Yes	7	6
39	7x38	Lig	Shared	34.6166	27.538	Yes	Yes	Yes	Yes	6	0
40	3x36	6x48	Shared	47.4213	94.9532	No	No	Yes	Yes	7	8
41	3x36	Lig	Shared	47.286	89.807	No	No	Yes	Yes	7	0
42	6x48	6x52	Shared	54.6502	14.7427	Yes	Yes	Yes	No	8	8
43	1x50	2x50	Shared	42.4718	46.807	No	Yes	No	Yes	9	9
44	6x44	6x48	Shared	100	83.5322	Yes	Yes	Yes	Yes	9	8
45	2x40	8x50	Shared	17.0127	28.0234	Yes	Yes	Yes	Yes	8	8
46	3x51	3x55	Shared	34.4563	10.2398	No	Yes	No	No	7	6
47	3x43	6x44	Shared	61.288	98.7135	No	Yes	Yes	Yes	8	9
48	2x46	3x43	Shared	21.2684	14.0526	Yes	Yes	No	Yes	9	8
49	Lig	NT	npy_on	0	27.6901	Yes	Yes	Yes	Yes	0	5
50	2x64	Lig	npy_on	0	10.6257	No	No	Yes	Yes	4	0
51	1x35	7x35	npy_on	0	12.7661	No	No	No	No	7	4
52	1x39	2x57	npy_on	7.98287	22.8538	Yes	Yes	No	Yes	7	7
53	7x38	7x42	npy_on	8.7769	11.7076	Yes	Yes	No	Yes	6	7
54	2x57	7x42	npy_on	7.70233	16.2982	No	Yes	No	Yes	7	7
55	2x46	2x50	npy_on	0	31.7661	Yes	Yes	No	Yes	9	9
56	1x50	2x51	npy_on	0	28.5673	No	Yes	No	No	9	8
57	3x43	7x49	npy_on	0	11.7485	No	Yes	No	Yes	8	9
58	2x50	7x49	npy_on	0	30.2632	No	Yes	No	Yes	9	9
59	2x54	2x57	npy_on	0	40.8947	No	No	No	Yes	7	7
60	2x54	7x46	npy_on	5.74606	41.2982	No	No	No	No	7	8
61	2x50	7x46	npy_on	6.88075	42.1871	No	Yes	No	No	9	8
62	1x50	7x50	npy_on	4.60637	16.3918	No	Yes	No	No	9	9
63	1x49	7x50	npy_on	3.46166	12.3099	No	No	No	No	8	9
64	3x43	7x53	npy_on	0	73.2105	No	Yes	Yes	Yes	8	9
65	2x43	7x53	npy_on	1.14971	60.4795	No	No	Yes	Yes	8	9
66	1x53	2x43	npy_on	0	12.4152	No	Yes	No	No	9	8
67	2x43	8x50	npy_on	0	54.4912	No	No	Yes	Yes	8	8
68	1x57	8x50	npy_on	0	10.6608	No	No	Yes	Yes	7	8
69	1x56	8x50	npy_on	2.29692	37.1988	No	No	Yes	Yes	7	8
70	1x56	8x53	npy_on	1.15472	14.614	No	No	No	No	7	5
71	1x56	8x54	npy_on	0	21.2866	No	No	No	No	7	5
72	2x37	2x40	npy_on	2.31195	14.2398	No	No	Yes	Yes	8	8
73	2x37	I1x51	npy_on	0	12.2398	No	No	No	Yes	8	6
74	4x61	Lig	npy_on	8.09809	33.0936	No	Yes	Yes	Yes	5	0
75	3x33	4x61	npy_on	2.337	43.5789	No	No	No	Yes	4	5
76	3x33	4x57	npy_on	1.16975	43.386	No	No	No	No	4	7
77	3x34	4x57	npy_on	0	43.9649	No	No	No	No	5	7
78	3x34	4x50	npy_on	6.6503	45.1053	No	No	No	Yes	5	9
79	4x46	4x50	npy_on	0	40.7368	No	Yes	No	Yes	7	9
80	2x42	4x46	npy_on	0	42.2047	No	Yes	No	Yes	7	7
81	2x42	3x49	npy_on	0	100	No	Yes	No	Yes	7	8
82	3x46	7x53	npy_on	0	66.8596	No	No	Yes	Yes	8	9
83	2x42	3x46	npy_on	3.31638	69.7719	No	Yes	No	No	7	8
84	2x39	3x49	npy_on	0	18.5614	No	No	No	Yes	7	8
85	2x39	2x40	npy_on	0	17.848	No	No	Yes	Yes	7	8
86	5x461	Lig	npy_on	0	13.1404	No	Yes	Yes	Yes	6	0
87	3x37	5x461	npy_on	3.09346	10.6667	No	No	No	Yes	6	6
88	2x51	2x55	npy_on	1.15723	16.3918	No	No	No	No	8	5
89	2x55	2x551	npy_on	0	12.3099	No	No	No	No	5	5
90	2x63	Lig	npy_on	0	12.8246	No	No	Yes	Yes	6	0
91	2x63	E1x50	npy_on	1.16474	10.9357	No	No	Yes	Yes	6	8
92	E1x50	E1x52	npy_on	6.60772	21.6667	Yes	Yes	Yes	Yes	8	7
93	E2	Lig	npy_on	0	38.6901	Yes	Yes	Yes	Yes	3	0
94	E1x50	E2	npy_on	0	14.883	Yes	Yes	Yes	Yes	8	3
95	4x61	4x65	npy_on	0	10.2632	No	Yes	Yes	Yes	5	5
96	3x49	3x53	npy_on	1.11715	98.7485	No	Yes	No	No	8	8
97	3x53	I2	npy_on	0	96.5614	No	No	Yes	Yes	8	6
98	5x64	I2	npy_on	0	73.6257	No	Yes	Yes	Yes	5	6
99	3x55	5x64	npy_on	6.45242	12.8713	No	No	No	Yes	6	5
100	3x52	I2	npy_on	0.0601157	14.4795	No	No	Yes	Yes	4	6
101	3x52	3x56	npy_on	1.05453	12.0175	No	No	No	No	4	6
102	5x47	5x48	npy_on	3.65454	18.386	Yes	Yes	No	No	8	5
103	5x45	5x48	npy_on	5.78864	16.5789	No	No	No	No	5	5
104	5x42	5x45	npy_on	0	14.7602	No	No	No	No	4	5
105	5x38	5x42	npy_on	1.4528	12.9298	No	No	No	No	4	4
106	5x35	5x38	npy_on	0	11.0877	No	No	No	No	3	4
107	6x54	7x37	npy_on	3.40906	10.0058	Yes	Yes	No	No	5	6
108	5x51	6x44	npy_on	0	19.8889	No	No	Yes	Yes	6	9
109	5x64	5x68	npy_on	4.2582	56.0117	No	Yes	No	No	5	6
110	5x68	6x26	npy_on	0	53.6374	No	No	No	Yes	6	4
111	6x26	6x30	npy_on	0	32.1813	No	Yes	No	Yes	4	7
112	7x55	8x54	npy_on	0	17.2807	No	No	No	No	6	5
113	7x55	8x51	npy_on	0	12.9649	No	No	No	No	6	8
114	8x48	8x51	npy_on	1.11715	10.7895	No	No	No	No	5	8
115	7x52	7x53	npy_on	0	13.7836	No	Yes	Yes	Yes	8	9
116	6x48	7x45	npy_on	7.15127	15.269	Yes	Yes	No	No	8	9
117	6x47	7x45	npy_on	6.14433	13.5497	No	No	No	No	8	9
118	6x47	7x43	npy_on	5.13238	12.3918	No	No	No	No	8	6
119	2x46	7x53	npy_on	0	22.6901	Yes	Yes	Yes	Yes	9	9
120	7x49	7x53	npy_on	0	19.7953	No	Yes	Yes	Yes	9	9
121	2x42	3x45	npy_on	2.2318	14.1579	No	Yes	No	No	7	7
122	5x47	5x51	npy_on	1.48536	16.7076	Yes	Yes	No	No	8	6

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
NT	NT	npy_off	10.55	0	1	1	1	1
7x28	NT	npy_off	6.335	0	0	0	2	1
1x39	7x38	Shared	8.4375	5.08	0	0	2	1
2x56	3x32	Shared	6.4875	6.61667	0	1	2	1
2x60	3x28	npy_off	4.45	0	1	1	1	2
2x60	7x38	Shared	6.5025	13.69	1	1	1	1
2x63	E1x50	Shared	11.0925	10.29	0	1	1	2
2x64	7x35	Shared	4.79	3.96333	0	1	1	2
2x67	E2	npy_off	5.72	0	0	0	1	1
E1x49	E2	Shared	12.9575	9.77	0	1	2	1
3x25	E1x50	Shared	5.5475	6.96333	1	1	2	2
E1x50	E2x50	Shared	5.55	3.91667	1	1	2	2
3x22	E2	Shared	12.4425	8.92667	1	1	2	1
3x25	E2	Shared	5.255	2.72667	1	1	2	1
3x25	E2x50	Shared	7.28	6.06667	1	1	2	2
3x29	4x65	Shared	13.985	4.89667	0	0	2	1
3x32	7x38	npy_off	4.9425	0	1	1	1	1
3x32	Lig	Shared	8.4625	8.06	1	1	1	0
3x36	6x48	Shared	8.35	3.62333	0	1	1	2
3x36	Lig	Shared	8.465	2.52	0	1	1	0
3x37	5x461	Shared	11.2175	5.55333	0	0	2	1
4x60	5x39	Shared	18.4275	6.02667	0	0	2	1
4x61	5x39	Shared	7.245	6.81333	0	1	1	1
4x61	Lig	Shared	7.5075	2.94	0	1	1	0
4x64	E2	Shared	30.195	13.3033	1	1	2	1
4x65	E2x50	npy_off	4.3775	0	0	1	1	2
4x65	E2x52	Shared	5.195	5.68333	0	1	1	1
E2	E2	Shared	80.31	84.06	1	1	1	1
E2	E2x51	Shared	14.58	4.62667	1	1	1	1
5x36	E2	Shared	10.61	8.30667	1	1	1	1
5x35	E2	npy_off	16.2275	0	1	0	2	1
5x33	5x36	npy_off	4.17	0	1	0	2	1
5x33	E3	npy_off	5.3575	0	1	0	2	1
5x36	E3	npy_off	6.4875	0	1	1	1	1
5x39	5x43	npy_off	9.385	0	0	1	1	1
5x40	6x59	Shared	9.8225	7.25667	1	1	1	1
5x40	Lig	Shared	5.9625	6.93333	1	1	1	0
5x44	6x52	Shared	3.95	1.71667	0	0	2	1
5x47	6x52	Shared	8.645	6.85333	0	0	2	1
6x48	6x52	Shared	5.895	3.57667	0	1	2	1
6x51	6x55	Shared	7.4275	4.10333	0	0	2	1
6x51	7x34	npy_off	4.875	0	0	0	2	1
6x52	Lig	npy_off	10.6025	0	0	0	1	0
6x54	6x58	Shared	12.0625	2.42667	1	0	1	1
6x54	7x33	Shared	6.49	3.32667	1	0	1	2
6x54	7x34	Shared	8.5725	6.78667	1	0	1	1
6x54	7x37	Shared	4.2625	5.18667	1	0	1	2
6x54	Lig	npy_off	4.6875	0	1	0	1	0
6x55	Lig	Shared	18.185	14.26	0	1	1	0
6x58	7x30	npy_off	5.4375	0	1	1	1	1
6x58	Lig	Shared	3.9925	18.7733	1	1	1	0
6x59	Lig	Shared	6.89	7.15	1	1	1	0
6x61	E3	Shared	6.8775	9.83333	0	0	2	1
7x30	E3	Shared	4.845	4.04333	1	1	1	1
7x27	7x30	npy_off	9.09	0	0	1	1	1
7x34	Lig	Shared	10.6325	11.39	1	1	1	0
7x38	7x42	Shared	12.8025	8.75667	1	1	1	2
7x38	Lig	Shared	4.92	5.07333	1	1	1	0
E2	NT	npy_off	17.355	0	1	1	1	1
6x54	7x30	Shared	4.9225	2.81667	1	0	1	1
2x60	Lig	Shared	4.985	9.60333	1	1	1	0
4x65	Lig	npy_off	4.11	0	0	1	1	0
3x33	4x61	Shared	3.65	2.43333	0	0	2	1
2x53	3x32	npy_off	3.5825	0	0	1	2	1
3x41	5x461	npy_off	3.285	0	0	0	2	1
2x64	7x31	npy_off	2.195	0	0	1	1	1
7x27	7x29	npy_off	2.1925	0	0	1	1	2
3x26	4x65	npy_off	2.035	0	0	0	2	1
7x26	7x30	npy_off	1.725	0	0	0	2	1
5x36	5x37	npy_off	1.2125	0	1	1	1	2
6x57	6x58	npy_off	0.655	0	0	0	2	1
1x32	NT	npy_on	0	3.32667	0	0	2	1
1x39	7x35	npy_on	0	5.57333	0	0	2	2
2x53	2x56	npy_on	0	2.81667	0	1	2	2
2x53	3x36	npy_on	0	2.54333	0	1	2	1
2x56	7x42	npy_on	0	2.7	0	1	2	2
2x60	3x32	npy_on	0	2.83333	1	1	1	1
2x63	Lig	npy_on	0	19.0333	0	1	1	0
2x67	Lig	npy_on	0	8.3	0	0	1	0
E1x50	E2	npy_on	0	3.25333	1	1	2	1
3x22	3x26	npy_on	0	3.6	1	1	2	2
3x28	3x32	npy_on	0	2.75333	0	0	2	1
E2	E2x50	npy_on	0	4.53333	1	1	1	2
E2	Lig	npy_on	0	42.4667	1	1	1	0
E2x51	Lig	npy_on	0	7.28667	0	1	1	0
E2	E2x52	npy_on	0	6.97667	1	1	1	1
5x39	E2	npy_on	0	3.23667	0	1	1	1
5x36	6x59	npy_on	0	6.35333	1	1	1	1
5x36	Lig	npy_on	0	5.18333	1	1	1	0
5x43	5x461	npy_on	0	8.15667	0	1	1	1
5x43	Lig	npy_on	0	5.10667	0	1	1	0
5x461	Lig	npy_on	0	4.14333	0	1	1	0
6x58	6x59	npy_on	0	2.61667	1	1	1	1
7x30	Lig	npy_on	0	7.68	1	1	1	0
7x31	Lig	npy_on	0	11.0133	0	0	1	0
Lig	NT	npy_on	0	3.18667	1	1	0	1
E3	Lig	npy_on	0	10.41	1	1	1	0
E2x52	Lig	npy_on	0	5.04	0	1	1	0
2x64	Lig	npy_on	0	2.52333	0	1	1	0
5x39	Lig	npy_on	0	3.41667	0	1	1	0
7x29	NT	npy_on	0	3.35333	0	0	2	1
2x53	7x42	npy_on	0	2.91333	0	1	2	2
2x63	E2	npy_on	0	3.43667	0	1	1	1
3x28	E1x50	npy_on	0	2.45667	0	0	2	2
4x61	4x65	npy_on	0	2.64333	0	1	1	1
4x65	E2	npy_on	0	2.88333	0	1	1	1
5x36	E2x52	npy_on	0	3.49	1	1	1	1
E3	E3	npy_on	0	3.59333	1	1	1	1
7x27	Lig	npy_on	0	2.21	0	1	1	0
7x28	7x29	npy_on	0	1.84	0	0	2	2
5x46	5x461	npy_on	0	1.83667	0	0	2	1
1x31	NT	npy_on	0	1.41333	0	0	2	1
5x33	E2	npy_on	0	1.03333	1	0	2	1
7x26	7x27	npy_on	0	0.903333	0	0	2	1
6x57	E3	npy_on	0	0.513333	0	0	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	npy_off	npy1_off npy2_off
	npy_on	npy1_on npy2_on npy4_on

Network Difference
Value	npy_off	npy_on
I_min	3.805	2.28667
Number of Linked Nodes	260	271
Number of Specific Nodes	0 (0.00%)	11 (4.06%)
Number of Shared Nodes	260 (100.00%)	260 (95.94%)
Number of Links	280	337
Number of Specific Links	111 (39.64%)	168 (49.85%)
Number of Shared Links	169 (60.36%)	169 (50.15%)
Number of Hubs	26	44
Number of Specific Hubs	6 (23.08%)	24 (54.55%)
Number of Shared Hubs	20 (76.92%)	20 (45.45%)
Average % Shared Neighbours (Jaccard)	43.28
Average % Shared Neighbours (Otsuka)	53.29
Average % Shared Neighbours (Overlap Coefficient)	63.16
Average % Shared Cliques (k3-6)	51.67
Graphlets Similarity	0.520421

Paths Difference
Value	npy_off	npy_on
Number Of Nodes in MetaPath	47	80
Specific Nodes in MetaPath	22 (46.81%)	55 (68.75%)
Shared Nodes in MetaPath	260 (100.00%)	260 (100.00%)
Number Of Links MetaPath	48	85
Specific Links in MetaPath	37 (77.08%)	74 (87.06%)
Shared Links in MetaPath	169 (60.36%)	169 (60.36%)
Number of Shortest Paths	62980	60960
Length Of Smallest Path	3	3
Average Path Length	14.7901	11.4216
Length of Longest Path	35	27
Minimum Path Strength	0.745	0.456667
Average Path Strength	5.85599	4.56366
Maximum Path Strength	23.775	28.3633
Minimum Path Correlation	0.7	0.703333
Average Path Correlation	0.924132	0.932492
Maximum Path Correlation	0.99	0.99
Minimum % Of Corr. Nodes	3.57143	4.7619
Average % Of Corr. Nodes	48.4826	57.8436
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	36.3871	49.445
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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