psnGPCR

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Orange: nodes, hubs and links specific of npy_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of npy_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	npy_on_gp Int. Strength	npy_off Int. Strength	npy_on_gp Hub1?	npy_off Hub1?	npy_on_gp Hub2?	npy_off Hub2?	ConSurf1	ConSurf2
1	1x32	NT	npy_on_gp	100	0	No	No	Yes	Yes	3	3
2	1x30	1x31	npy_on_gp	100	0	No	No	No	No	2	4
3	1x35	7x35	npy_on_gp	100	0	No	No	No	No	7	4
4	1x39	7x35	npy_on_gp	100	0	Yes	Yes	No	No	7	4
5	1x42	2x57	npy_on_gp	100	0	No	No	Yes	No	7	7
6	1x42	7x39	npy_on_gp	100	0	No	No	No	No	7	5
7	1x50	2x51	npy_on_gp	100	0	Yes	No	No	No	9	8
8	1x53	1x57	npy_on_gp	100	0	Yes	No	No	No	9	7
9	1x53	2x43	npy_on_gp	100	0	Yes	No	No	No	9	8
10	1x56	8x54	npy_on_gp	100	0	No	No	No	No	7	5
11	1x57	8x50	npy_on_gp	100	0	No	No	Yes	Yes	7	8
12	1x60	8x50	npy_on_gp	100	0	No	No	Yes	Yes	5	8
13	I1x49	I1x51	npy_on_gp	100	0	No	No	Yes	No	5	6
14	2x39	3x49	npy_on_gp	100	0	No	No	Yes	No	7	8
15	2x42	3x49	npy_on_gp	100	0	Yes	No	Yes	No	7	8
16	2x42	4x46	npy_on_gp	100	0	Yes	No	Yes	No	7	7
17	2x46	2x50	npy_on_gp	100	0	Yes	Yes	Yes	No	9	9
18	2x46	7x53	npy_on_gp	100	0	Yes	Yes	Yes	Yes	9	9
19	2x49	3x39	npy_on_gp	100	0	No	No	No	No	8	9
20	2x50	7x49	npy_on_gp	100	0	Yes	No	Yes	No	9	9
21	2x52	3x35	npy_on_gp	100	0	No	No	No	No	7	8
22	2x53	2x56	npy_on_gp	100	0	Yes	No	No	No	7	7
23	2x53	3x36	npy_on_gp	100	0	Yes	No	No	No	7	7
24	2x54	2x57	npy_on_gp	100	0	No	No	Yes	No	7	7
25	2x55	2x551	npy_on_gp	100	0	No	No	No	No	5	5
26	2x56	7x42	npy_on_gp	100	0	No	No	Yes	No	7	7
27	2x57	2x58	npy_on_gp	100	0	Yes	No	No	No	7	8
28	2x59	3x28	npy_on_gp	100	0	No	No	No	No	6	5
29	2x60	3x32	npy_on_gp	100	0	No	No	Yes	Yes	6	6
30	2x63	Lig	npy_on_gp	100	0	No	No	Yes	Yes	6	0
31	2x66	E1x49	npy_on_gp	100	0	No	No	No	No	3	5
32	2x67	Lig	npy_on_gp	100	0	No	No	Yes	Yes	4	0
33	E1x49	E1x51	npy_on_gp	100	0	No	No	No	No	5	2
34	E1x50	E2	npy_on_gp	100	0	Yes	Yes	Yes	Yes	8	3
35	3x24	E1x52	npy_on_gp	100	0	No	No	Yes	Yes	6	7
36	3x22	3x26	npy_on_gp	100	0	No	No	No	No	3	7
37	3x28	3x32	npy_on_gp	100	0	No	No	Yes	Yes	5	6
38	3x30	4x57	npy_on_gp	100	0	No	No	No	No	6	7
39	3x34	4x57	npy_on_gp	100	0	No	No	No	No	5	7
40	3x40	6x48	npy_on_gp	100	0	No	No	Yes	Yes	7	8
41	3x43	7x49	npy_on_gp	100	0	Yes	No	Yes	No	8	9
42	3x43	7x53	npy_on_gp	100	0	Yes	No	Yes	Yes	8	9
43	3x44	5x50	npy_on_gp	100	0	No	No	No	No	7	9
44	3x45	4x49	npy_on_gp	100	0	No	No	No	No	7	7
45	3x46	3x50	npy_on_gp	100	0	No	No	No	Yes	8	9
46	3x46	7x53	npy_on_gp	100	0	No	No	Yes	Yes	8	9
47	3x50	5x58	npy_on_gp	100	0	No	Yes	Yes	No	9	9
48	3x50	7x53	npy_on_gp	100	0	No	Yes	Yes	Yes	9	9
49	3x51	5x57	npy_on_gp	100	0	Yes	No	No	No	7	7
50	3x53	I2	npy_on_gp	100	0	No	No	Yes	Yes	8	6
51	5x64	I2	npy_on_gp	100	0	Yes	No	Yes	Yes	5	6
52	4x41	I2	npy_on_gp	100	0	No	No	Yes	Yes	4	6
53	4x39	4x43	npy_on_gp	100	0	No	No	No	No	2	3
54	4x46	4x50	npy_on_gp	100	0	Yes	No	Yes	No	7	9
55	4x59	4x63	npy_on_gp	100	0	No	No	No	No	4	4
56	E2	E2x50	npy_on_gp	100	0	Yes	Yes	No	No	3	9
57	E2	Lig	npy_on_gp	100	0	Yes	Yes	Yes	Yes	3	0
58	E2x51	Lig	npy_on_gp	100	0	No	No	Yes	Yes	3	0
59	E2	E2x52	npy_on_gp	100	0	Yes	Yes	Yes	No	3	4
60	5x39	E2	npy_on_gp	100	0	Yes	No	Yes	Yes	6	3
61	5x36	6x59	npy_on_gp	100	0	Yes	Yes	Yes	No	4	4
62	5x36	Lig	npy_on_gp	100	0	Yes	Yes	Yes	Yes	4	0
63	5x43	5x461	npy_on_gp	100	0	No	No	Yes	No	5	6
64	5x43	Lig	npy_on_gp	100	0	No	No	Yes	Yes	5	0
65	5x461	Lig	npy_on_gp	100	0	Yes	No	Yes	Yes	6	0
66	5x51	6x44	npy_on_gp	100	0	No	No	Yes	Yes	6	9
67	5x54	5x58	npy_on_gp	100	0	No	No	Yes	No	8	9
68	5x58	6x40	npy_on_gp	100	0	Yes	No	No	No	9	7
69	5x58	6x41	npy_on_gp	100	0	Yes	No	No	No	9	8
70	5x62	6x34	npy_on_gp	100	0	No	No	No	No	5	6
71	5x65	5x69	npy_on_gp	100	0	No	No	No	No	8	3
72	5x66	5x70	npy_on_gp	100	0	No	No	No	No	4	4
73	5x70	6x30	npy_on_gp	100	0	No	No	Yes	No	4	7
74	6x23	6x26	npy_on_gp	100	0	No	No	Yes	No	3	4
75	6x27	6x30	npy_on_gp	100	0	No	No	Yes	No	4	7
76	6x31	6x35	npy_on_gp	100	0	No	No	No	No	6	6
77	6x40	7x53	npy_on_gp	100	0	No	No	Yes	Yes	7	9
78	6x49	6x50	npy_on_gp	100	0	No	No	No	No	6	9
79	6x51	7x41	npy_on_gp	100	0	No	No	No	No	7	8
80	6x58	6x59	npy_on_gp	100	0	No	Yes	Yes	No	4	4
81	7x30	Lig	npy_on_gp	100	0	No	Yes	Yes	Yes	3	0
82	7x31	Lig	npy_on_gp	100	0	No	No	Yes	Yes	4	0
83	7x49	7x53	npy_on_gp	100	0	Yes	No	Yes	Yes	9	9
84	7x55	8x51	npy_on_gp	100	0	No	No	No	No	6	8
85	7x55	8x54	npy_on_gp	100	0	No	No	No	No	6	5
86	8x49	8x50	npy_on_gp	100	0	No	No	Yes	Yes	6	8
87	8x55	8x56	npy_on_gp	100	0	No	No	No	No	4	4
88	Lig	Lig	npy_on_gp	100	0	Yes	Yes	Yes	Yes	0	0
89	Lig	NT	npy_on_gp	100	0	Yes	Yes	Yes	Yes	0	3
90	E3	Lig	npy_on_gp	100	0	Yes	Yes	Yes	Yes	3	0
91	E2x52	Lig	npy_on_gp	100	0	Yes	No	Yes	Yes	4	0
92	2x64	Lig	npy_on_gp	100	0	No	No	Yes	Yes	4	0
93	5x39	Lig	npy_on_gp	100	0	Yes	No	Yes	Yes	6	0
94	7x29	NT	npy_on_gp	100	0	No	No	Yes	Yes	3	3
95	2x39	2x40	npy_on_gp	100	0	No	No	Yes	Yes	7	8
96	2x43	8x50	npy_on_gp	100	0	No	No	Yes	Yes	8	8
97	2x53	7x42	npy_on_gp	100	0	Yes	No	Yes	No	7	7
98	2x63	E2	npy_on_gp	100	0	No	No	Yes	Yes	6	3
99	3x28	E1x50	npy_on_gp	100	0	No	No	Yes	Yes	5	8
100	3x51	3x56	npy_on_gp	100	0	Yes	No	No	No	7	6
101	3x54	5x61	npy_on_gp	100	0	No	No	No	No	8	8
102	5x49	5x53	npy_on_gp	100	0	No	No	No	No	5	6
103	5x66	6x30	npy_on_gp	100	0	No	No	Yes	No	4	7
104	6x26	6x27	npy_on_gp	100	0	Yes	No	No	No	4	4
105	6x26	6x30	npy_on_gp	100	0	Yes	No	Yes	No	4	7
106	7x52	7x53	npy_on_gp	100	0	Yes	No	Yes	Yes	8	9
107	8x55	8x59	npy_on_gp	100	0	No	No	No	No	4	0
108	4x61	4x65	npy_on_gp	100	0	Yes	No	Yes	Yes	5	5
109	4x65	E2	npy_on_gp	100	0	Yes	Yes	Yes	Yes	5	3
110	5x36	E2x52	npy_on_gp	100	0	Yes	Yes	Yes	No	4	4
111	5x54	6x44	npy_on_gp	100	0	No	No	Yes	Yes	8	9
112	5x71	5x72	npy_on_gp	100	0	No	No	No	No	2	5
113	6x26	I3	npy_on_gp	100	0	Yes	No	No	No	4	4
114	E3	E3	npy_on_gp	100	0	Yes	Yes	Yes	Yes	3	3
115	6x32	6x36	npy_on_gp	66.6667	0	No	No	No	No	7	8
116	5x65	6x30	npy_on_gp	33.3333	0	No	No	Yes	No	8	7
117	7x29	7x32	npy_on_gp	33.3333	0	No	No	No	No	3	2
118	7x27	Lig	npy_on_gp	33.3333	0	No	No	Yes	Yes	1	0
119	5x68	6x26	npy_on_gp	33.3333	0	No	No	Yes	No	6	4
120	1x54	2x44	npy_on_gp	33.3333	0	No	No	No	No	7	5
121	1x52	8x53	npy_on_gp	33.3333	0	No	No	No	No	6	5
122	5x58	5x61	npy_on_gp	66.6667	0	Yes	No	No	No	9	8
123	2x37	I1x51	npy_on_gp	33.3333	0	No	No	Yes	No	8	6
124	6x43	7x52	npy_on_gp	33.3333	0	No	No	Yes	No	7	8
125	5x65	6x33	npy_on_gp	0	0	No	No	No	No	8	7
126	2x40	I1x50	npy_on_gp	33.3333	0	Yes	Yes	No	No	8	7
127	7x28	7x29	npy_on_gp	33.3333	0	No	No	No	No	2	3
128	5x46	5x461	npy_on_gp	66.6667	0	No	No	Yes	No	5	6
129	1x45	1x46	npy_on_gp	33.3333	0	No	No	No	No	5	7
130	6x24	6x28	npy_on_gp	33.3333	0	No	No	No	No	2	4
131	5x70	5x71	npy_on_gp	33.3333	0	No	No	No	No	4	2
132	3x34	4x54	npy_on_gp	0	0	No	No	No	No	5	4
133	3x21	E1x52	npy_on_gp	33.3333	0	No	No	Yes	Yes	8	7
134	6x30	6x31	npy_on_gp	33.3333	0	Yes	No	No	No	7	6
135	3x44	3x48	npy_on_gp	0	0	No	No	No	No	7	6
136	2x41	I1x51	npy_on_gp	33.3333	0	No	No	Yes	No	5	6
137	1x31	NT	npy_on_gp	33.3333	0	No	No	Yes	Yes	4	3
138	5x73	I3	npy_on_gp	33.3333	0	No	No	No	No	4	4
139	6x22	I3	npy_on_gp	33.3333	0	No	No	No	No	3	4
140	5x63	5x67	npy_on_gp	33.3333	0	No	No	No	No	3	4
141	5x35	5x38	npy_on_gp	33.3333	0	No	No	No	No	3	4
142	5x42	5x45	npy_on_gp	33.3333	0	No	No	No	No	4	5
143	8x53	8x56	npy_on_gp	33.3333	0	No	No	No	No	5	4
144	4x44	4x45	npy_on_gp	0	0	No	No	No	No	3	5
145	4x45	4x48	npy_on_gp	0	0	No	No	No	No	5	4
146	1x53	7x54	npy_on_gp	0	0	Yes	No	No	No	9	7
147	5x32	5x34	npy_on_gp	33.3333	0	No	No	No	No	3	1
148	6x39	7x52	npy_on_gp	33.3333	0	No	No	Yes	No	5	8
149	5x33	E2	npy_on_gp	33.3333	0	No	No	Yes	Yes	1	3
150	6x25	6x26	npy_on_gp	33.3333	0	No	No	Yes	No	3	4
151	5x34	5x37	npy_on_gp	33.3333	0	No	No	No	No	1	3
152	3x23	3x26	npy_on_gp	0	0	No	No	No	No	1	7
153	1x47	1x51	npy_on_gp	0	0	No	No	No	No	7	4
154	6x28	6x29	npy_on_gp	33.3333	0	No	No	No	No	4	6
155	4x52	4x56	npy_on_gp	33.3333	0	No	No	No	No	5	5
156	8x54	8x57	npy_on_gp	0	0	No	No	No	No	5	0
157	7x26	7x27	npy_on_gp	33.3333	0	No	No	No	No	0	1
158	5x59	5x62	npy_on_gp	33.3333	0	No	No	No	No	4	5
159	4x46	4x47	npy_on_gp	33.3333	0	Yes	No	No	No	7	4
160	6x46	6x47	npy_on_gp	0	0	No	No	No	No	6	8
161	1x33	1x34	npy_on_gp	0	0	No	No	No	No	6	5
162	6x38	6x41	npy_on_gp	0	0	No	No	No	No	5	8
163	6x39	6x42	npy_on_gp	0	0	No	No	No	No	5	5
164	4x54	4x55	npy_on_gp	0	0	No	No	No	No	4	3
165	6x57	E3	npy_on_gp	0	0	No	No	Yes	Yes	4	3
166	1x41	1x45	npy_on_gp	0	0	No	No	No	No	5	5
167	4x48	4x51	npy_on_gp	0	0	No	No	No	No	4	4
168	1x29	1x30	npy_on_gp	0	0	No	No	No	No	3	2
169	1x28	1x31	Shared	100	100	No	No	No	No	4	4
170	1x33	1x37	Shared	100	100	No	No	No	No	6	5
171	1x39	2x57	Shared	100	100	Yes	Yes	Yes	No	7	7
172	1x39	2x61	Shared	100	100	Yes	Yes	No	No	7	6
173	1x39	7x38	Shared	100	100	Yes	Yes	Yes	Yes	7	6
174	1x39	7x39	Shared	100	100	Yes	Yes	No	No	7	5
175	1x43	2x57	Shared	100	100	No	No	Yes	No	7	7
176	1x47	2x51	Shared	100	0	No	No	No	No	7	8
177	1x48	1x49	Shared	100	0	No	No	No	No	5	8
178	1x50	2x47	Shared	100	100	Yes	No	No	No	9	9
179	1x50	2x50	Shared	100	100	Yes	No	Yes	No	9	9
180	1x50	7x50	Shared	100	100	Yes	No	No	No	9	9
181	1x53	2x47	Shared	100	25	Yes	No	No	No	9	9
182	1x54	1x58	Shared	100	0	No	No	No	No	7	4
183	1x56	8x50	Shared	100	50	No	No	Yes	Yes	7	8
184	1x56	8x53	Shared	100	75	No	No	No	No	7	5
185	2x37	2x40	Shared	100	100	No	No	Yes	Yes	8	8
186	2x38	3x49	Shared	100	100	No	No	Yes	No	6	8
187	2x38	4x42	Shared	100	50	No	No	No	No	6	7
188	2x40	8x50	Shared	100	100	Yes	Yes	Yes	Yes	8	8
189	2x41	4x43	Shared	100	100	No	No	No	No	5	3
190	2x42	3x45	Shared	100	100	Yes	No	No	No	7	7
191	2x42	3x46	Shared	100	100	Yes	No	No	No	7	8
192	2x45	4x46	Shared	100	100	No	No	Yes	No	9	7
193	2x45	4x50	Shared	100	100	No	No	Yes	No	9	9
194	2x46	3x42	Shared	100	50	Yes	Yes	No	No	9	8
195	2x46	3x43	Shared	100	100	Yes	Yes	Yes	No	9	8
196	2x46	7x49	Shared	100	50	Yes	Yes	Yes	No	9	9
197	2x48	2x52	Shared	100	50	No	No	No	No	6	7
198	2x49	3x38	Shared	100	50	No	No	No	No	8	7
199	2x50	3x39	Shared	100	50	Yes	No	No	No	9	9
200	2x50	7x46	Shared	100	100	Yes	No	No	No	9	8
201	2x53	3x35	Shared	100	50	Yes	No	No	No	7	8
202	2x551	3x31	Shared	100	50	No	No	No	No	5	5
203	2x56	3x32	Shared	100	100	No	No	Yes	Yes	7	6
204	2x57	7x42	Shared	100	100	Yes	No	Yes	No	7	7
205	2x59	E1x52	Shared	100	100	No	No	Yes	Yes	6	7
206	2x60	7x38	Shared	100	100	No	No	Yes	Yes	6	6
207	2x60	Lig	Shared	100	100	No	No	Yes	Yes	6	0
208	2x62	E1x52	Shared	100	25	No	No	Yes	Yes	4	7
209	2x63	E1x50	Shared	100	100	No	No	Yes	Yes	6	8
210	2x64	7x35	Shared	100	100	No	No	No	No	4	4
211	2x66	E1x51	Shared	100	100	No	No	No	No	3	2
212	E1x49	E2	Shared	100	100	No	No	Yes	Yes	5	3
213	E1x50	E1x52	Shared	100	100	Yes	Yes	Yes	Yes	8	7
214	3x25	E1x50	Shared	100	100	No	No	Yes	Yes	9	8
215	E1x50	E2x50	Shared	100	100	Yes	Yes	No	No	8	9
216	3x22	E2	Shared	100	100	No	No	Yes	Yes	3	3
217	3x25	E2x50	Shared	100	100	No	No	No	No	9	9
218	3x29	4x65	Shared	100	100	No	No	Yes	Yes	6	5
219	3x30	4x62	Shared	100	100	No	No	No	No	6	5
220	3x32	Lig	Shared	100	100	Yes	Yes	Yes	Yes	6	0
221	3x33	4x57	Shared	100	100	No	No	No	No	4	7
222	3x34	4x50	Shared	100	100	No	No	Yes	No	5	9
223	3x36	6x48	Shared	100	100	No	No	Yes	Yes	7	8
224	3x37	4x53	Shared	100	100	No	No	No	No	6	8
225	3x37	4x56	Shared	100	50	No	No	No	No	6	5
226	3x37	5x461	Shared	100	100	No	No	Yes	No	6	6
227	3x38	4x50	Shared	100	100	No	No	Yes	No	7	9
228	3x40	5x50	Shared	100	100	No	No	No	No	7	9
229	3x40	6x44	Shared	100	100	No	No	Yes	Yes	7	9
230	3x41	4x49	Shared	100	100	No	Yes	No	No	7	7
231	3x43	6x44	Shared	100	100	Yes	No	Yes	Yes	8	9
232	3x47	5x54	Shared	100	100	No	No	No	No	9	8
233	3x47	5x58	Shared	100	100	No	No	Yes	No	9	9
234	3x49	3x53	Shared	100	100	Yes	No	No	No	8	8
235	3x51	3x55	Shared	100	100	Yes	No	No	No	7	6
236	3x51	5x60	Shared	100	100	Yes	No	No	No	7	4
237	3x52	3x56	Shared	100	100	No	No	No	No	4	6
238	3x55	3x56	Shared	100	75	No	No	No	No	6	6
239	3x55	5x64	Shared	100	100	No	No	Yes	No	6	5
240	I2	I2	Shared	100	100	Yes	Yes	Yes	Yes	6	6
241	4x38	4x40	Shared	100	100	No	No	No	No	7	5
242	4x44	4x48	Shared	100	0	No	No	No	No	3	4
243	4x59	4x60	Shared	100	50	No	No	No	No	4	8
244	4x60	5x39	Shared	100	100	No	No	Yes	No	8	6
245	4x61	5x39	Shared	100	100	Yes	No	Yes	No	5	6
246	4x63	4x64	Shared	100	100	No	No	No	No	4	5
247	4x64	E2	Shared	100	100	No	No	Yes	Yes	5	3
248	4x65	E2x52	Shared	100	100	Yes	Yes	Yes	No	5	4
249	E2	E2	Shared	100	100	Yes	Yes	Yes	Yes	3	3
250	E2	E2x51	Shared	100	100	Yes	Yes	No	No	3	3
251	5x36	E2	Shared	100	100	Yes	Yes	Yes	Yes	4	3
252	5x32	5x35	Shared	100	100	No	No	No	No	3	3
253	5x37	6x60	Shared	100	100	No	No	No	No	3	4
254	5x40	6x59	Shared	100	100	No	No	Yes	No	5	4
255	5x40	Lig	Shared	100	100	No	No	Yes	Yes	5	0
256	5x44	6x56	Shared	100	0	No	No	No	No	6	6
257	5x45	5x48	Shared	100	0	No	No	No	No	5	5
258	5x47	6x49	Shared	100	100	Yes	Yes	No	No	8	6
259	5x47	6x52	Shared	100	100	Yes	Yes	No	Yes	8	8
260	5x49	5x50	Shared	100	100	No	No	No	No	5	9
261	5x51	6x45	Shared	100	100	No	No	No	No	6	6
262	5x56	5x60	Shared	100	100	No	No	No	No	4	4
263	5x58	6x37	Shared	100	100	Yes	No	No	No	9	8
264	5x62	5x66	Shared	100	100	No	No	No	No	5	4
265	5x64	5x68	Shared	100	50	Yes	No	No	No	5	6
266	6x36	7x56	Shared	100	100	No	No	No	No	8	6
267	6x40	7x52	Shared	100	100	No	No	Yes	No	7	8
268	6x44	6x48	Shared	100	100	Yes	Yes	Yes	Yes	9	8
269	6x47	7x45	Shared	100	50	No	No	No	No	8	9
270	6x48	6x52	Shared	100	100	Yes	Yes	No	Yes	8	8
271	6x48	7x45	Shared	100	100	Yes	Yes	No	No	8	9
272	6x50	7x37	Shared	100	100	No	No	No	No	9	6
273	6x50	7x40	Shared	100	100	No	No	No	No	9	7
274	6x51	6x55	Shared	100	100	No	No	No	No	7	5
275	6x54	7x30	Shared	100	100	Yes	Yes	No	Yes	5	3
276	6x54	7x33	Shared	100	100	Yes	Yes	No	No	5	6
277	6x54	7x34	Shared	100	100	Yes	Yes	No	No	5	5
278	6x54	7x37	Shared	100	100	Yes	Yes	No	No	5	6
279	6x55	Lig	Shared	100	100	No	No	Yes	Yes	5	0
280	6x58	Lig	Shared	100	100	No	Yes	Yes	Yes	4	0
281	6x59	Lig	Shared	100	100	Yes	No	Yes	Yes	4	0
282	6x61	E3	Shared	100	100	No	No	Yes	Yes	4	3
283	7x30	E3	Shared	100	100	No	Yes	Yes	Yes	3	3
284	7x34	Lig	Shared	100	100	No	No	Yes	Yes	5	0
285	7x38	7x42	Shared	100	100	Yes	Yes	Yes	No	6	7
286	8x47	8x49	Shared	100	0	No	No	No	No	8	6
287	8x47	8x50	Shared	100	100	No	No	Yes	Yes	8	8
288	8x48	8x52	Shared	100	100	No	No	No	No	5	5
289	4x61	Lig	Shared	100	100	Yes	No	Yes	Yes	5	0
290	3x36	Lig	Shared	100	100	No	No	Yes	Yes	7	0
291	7x38	Lig	Shared	100	100	Yes	Yes	Yes	Yes	6	0
292	1x55	1x59	Shared	100	50	No	No	No	No	3	5
293	2x43	7x53	Shared	100	100	No	No	Yes	Yes	8	9
294	2x45	3x42	Shared	100	100	No	No	No	No	9	8
295	2x54	7x46	Shared	100	100	No	No	No	No	7	8
296	3x33	4x61	Shared	100	50	No	No	Yes	No	4	5
297	3x52	I2	Shared	100	100	No	No	Yes	Yes	4	6
298	5x47	5x51	Shared	100	100	Yes	Yes	No	No	8	6
299	6x25	6x29	Shared	100	50	No	No	No	No	3	6
300	6x54	6x58	Shared	100	100	Yes	Yes	No	Yes	5	4
301	7x43	7x47	Shared	100	50	No	No	No	Yes	6	8
302	E1x51	E1x52	Shared	100	50	No	No	Yes	Yes	2	7
303	3x25	E2	Shared	100	100	No	No	Yes	Yes	9	3
304	5x64	5x67	Shared	100	50	Yes	No	No	No	5	4
305	7x51	7x55	Shared	100	25	No	No	No	No	6	6
306	7x48	7x52	Shared	33.3333	50	No	No	Yes	No	6	8
307	6x47	7x43	Shared	33.3333	0	No	No	No	No	8	6
308	1x57	2x44	Shared	33.3333	100	No	No	No	No	7	5
309	5x38	5x42	Shared	33.3333	0	No	No	No	No	4	4
310	1x38	7x39	Shared	0	0	No	No	No	No	6	5
311	1x59	1x60	Shared	33.3333	25	No	No	No	No	5	5
312	5x55	6x41	Shared	0	0	No	No	No	No	5	8
313	1x44	1x48	Shared	33.3333	100	No	No	No	No	5	5
314	8x48	8x51	Shared	33.3333	100	No	No	No	No	5	8
315	1x46	7x47	Shared	33.3333	0	No	No	No	Yes	7	8
316	1x32	2x65	Shared	33.3333	100	No	No	No	No	3	4
317	1x40	1x43	Shared	33.3333	25	No	No	No	No	5	7
318	5x44	6x52	Shared	33.3333	100	No	No	No	Yes	6	8
319	6x32	8x48	Shared	33.3333	100	No	No	No	No	7	5
320	I1x48	I1x51	Shared	33.3333	100	No	No	Yes	No	6	6
321	3x45	4x45	Shared	33.3333	0	No	No	No	No	7	5
322	5x47	5x48	Shared	33.3333	100	Yes	Yes	No	No	8	5
323	1x36	2x65	Shared	33.3333	100	No	No	No	No	5	4
324	1x52	8x58	Shared	33.3333	100	No	No	No	No	6	0
325	2x51	2x55	Shared	33.3333	0	No	No	No	No	8	5
326	5x41	6x60	Shared	33.3333	50	No	No	No	No	5	4
327	3x41	4x52	Shared	0	25	No	Yes	No	No	7	5
328	1x34	1x35	Shared	0	0	No	No	No	No	5	7
329	1x49	7x50	Shared	33.3333	100	No	No	No	No	8	9
330	6x38	6x42	Shared	0	0	No	No	No	No	5	5
331	6x42	6x46	Shared	0	0	No	No	No	No	5	6
332	4x38	4x41	Shared	0	50	No	No	No	No	7	4
333	3x27	3x31	Shared	0	25	No	No	No	No	5	5
334	7x32	7x36	Shared	0	0	No	No	No	No	2	6
335	6x49	6x53	Shared	0	25	No	No	No	No	6	5
336	8x58	CT	Shared	0	0	No	No	No	No	0	0
337	1x29	1x32	Shared	0	25	No	No	No	No	3	3
338	NT	NT	npy_off	0	100	Yes	Yes	Yes	Yes	3	3
339	7x28	NT	npy_off	0	100	No	No	Yes	Yes	2	3
340	1x42	7x47	npy_off	0	100	No	No	No	Yes	7	8
341	1x45	7x47	npy_off	0	100	No	No	No	Yes	5	8
342	1x53	7x53	npy_off	0	100	Yes	No	Yes	Yes	9	9
343	1x57	2x40	npy_off	0	100	No	No	Yes	Yes	7	8
344	1x60	I1x50	npy_off	0	100	No	No	No	No	5	7
345	2x39	3x50	npy_off	0	100	No	No	No	Yes	7	9
346	2x40	7x53	npy_off	0	100	Yes	Yes	Yes	Yes	8	9
347	2x41	4x39	npy_off	0	100	No	No	No	No	5	2
348	2x46	3x39	npy_off	0	100	Yes	Yes	No	No	9	9
349	2x59	3x24	npy_off	0	100	No	No	No	No	6	6
350	2x60	3x28	npy_off	0	100	No	No	No	No	6	5
351	2x61	2x65	npy_off	0	100	No	No	No	No	6	4
352	2x67	E2	npy_off	0	100	No	No	Yes	Yes	4	3
353	3x30	3x34	npy_off	0	100	No	No	No	No	6	5
354	3x32	7x38	npy_off	0	100	Yes	Yes	Yes	Yes	6	6
355	3x39	6x44	npy_off	0	100	No	No	Yes	Yes	9	9
356	3x41	5x50	npy_off	0	100	No	Yes	No	No	7	9
357	3x43	6x41	npy_off	0	100	Yes	No	No	No	8	8
358	3x44	5x54	npy_off	0	100	No	No	No	No	7	8
359	3x46	6x37	npy_off	0	100	No	No	No	No	8	8
360	3x49	I2	npy_off	0	100	Yes	No	Yes	Yes	8	6
361	3x50	6x33	npy_off	0	100	No	Yes	No	No	9	7
362	3x50	6x34	npy_off	0	100	No	Yes	No	No	9	6
363	3x50	6x37	npy_off	0	100	No	Yes	No	No	9	8
364	3x51	5x61	npy_off	0	100	Yes	No	No	No	7	8
365	3x56	I2	npy_off	0	100	No	No	Yes	Yes	6	6
366	4x40	4x43	npy_off	0	100	No	No	No	No	5	3
367	4x65	E2x50	npy_off	0	100	Yes	Yes	No	No	5	9
368	5x35	E2	npy_off	0	100	No	No	Yes	Yes	3	3
369	5x33	5x36	npy_off	0	100	No	No	Yes	Yes	1	4
370	5x33	E3	npy_off	0	100	No	No	Yes	Yes	1	3
371	5x36	E3	npy_off	0	100	Yes	Yes	Yes	Yes	4	3
372	5x39	5x43	npy_off	0	100	Yes	No	No	No	6	5
373	5x44	5x48	npy_off	0	100	No	No	No	No	6	5
374	5x54	6x41	npy_off	0	100	No	No	No	No	8	8
375	5x58	6x38	npy_off	0	100	Yes	No	No	No	9	5
376	6x36	7x53	npy_off	0	100	No	No	Yes	Yes	8	9
377	6x36	8x47	npy_off	0	100	No	No	No	No	8	8
378	6x40	7x49	npy_off	0	100	No	No	Yes	No	7	9
379	6x48	7x41	npy_off	0	100	Yes	Yes	No	No	8	8
380	6x51	7x34	npy_off	0	100	No	No	No	No	7	5
381	6x52	Lig	npy_off	0	100	No	Yes	Yes	Yes	8	0
382	6x54	Lig	npy_off	0	100	Yes	Yes	Yes	Yes	5	0
383	6x58	7x30	npy_off	0	100	No	Yes	No	Yes	4	3
384	7x27	7x30	npy_off	0	100	No	No	No	Yes	1	3
385	8x50	8x54	npy_off	0	100	Yes	Yes	No	No	8	5
386	E2	NT	npy_off	0	100	Yes	Yes	Yes	Yes	3	3
387	4x65	Lig	npy_off	0	100	Yes	Yes	Yes	Yes	5	0
388	1x52	8x54	npy_off	0	100	No	No	No	No	6	5
389	8x50	I1x50	npy_off	0	100	Yes	Yes	No	No	8	7
390	3x54	6x30	npy_off	0	100	No	No	Yes	No	8	7
391	6x30	I2	npy_off	0	100	Yes	No	Yes	Yes	7	6
392	5x68	6x27	npy_off	0	100	No	No	No	No	6	4
393	6x27	6x31	npy_off	0	100	No	No	No	No	4	6
394	7x55	7x56	npy_off	0	100	No	No	No	No	6	6
395	5x59	5x63	npy_off	0	50	No	No	No	No	4	3
396	6x34	6x35	npy_off	0	50	No	No	No	No	6	6
397	3x30	4x54	npy_off	0	50	No	No	No	No	6	4
398	2x53	3x32	npy_off	0	50	Yes	No	Yes	Yes	7	6
399	5x53	5x57	npy_off	0	50	No	No	No	No	6	7
400	6x26	I2	npy_off	0	50	Yes	No	Yes	Yes	4	6
401	8x57	8x58	npy_off	0	50	No	No	No	No	0	0
402	6x28	6x32	npy_off	0	50	No	No	No	No	4	7
403	1x43	2x58	npy_off	0	25	No	No	No	No	7	8
404	2x37	I1x49	npy_off	0	50	No	No	No	No	8	5
405	3x41	5x461	npy_off	0	50	No	Yes	Yes	No	7	6
406	6x39	7x56	npy_off	0	50	No	No	No	No	5	6
407	5x34	5x35	npy_off	0	75	No	No	No	No	1	3
408	3x44	5x53	npy_off	0	0	No	No	No	No	7	6
409	1x54	2x47	npy_off	0	50	No	No	No	No	7	9
410	5x62	5x63	npy_off	0	50	No	No	No	No	5	3
411	1x54	2x48	npy_off	0	50	No	No	No	No	7	6
412	5x61	6x34	npy_off	0	25	No	No	No	No	8	6
413	5x62	6x35	npy_off	0	50	No	No	No	No	5	6
414	4x48	4x52	npy_off	0	50	No	No	No	No	4	5
415	3x54	5x65	npy_off	0	0	No	No	No	No	8	8
416	1x51	2x51	npy_off	0	25	No	No	No	No	4	8
417	3x48	5x53	npy_off	0	0	No	No	No	No	6	6
418	2x38	4x39	npy_off	0	0	No	No	No	No	6	2
419	2x56	3x31	npy_off	0	0	No	No	No	No	7	5
420	6x29	6x32	npy_off	0	50	No	No	No	No	6	7
421	6x43	7x48	npy_off	0	25	No	No	No	No	7	6
422	5x45	5x46	npy_off	0	50	No	No	No	No	5	5
423	7x32	7x35	npy_off	0	50	No	No	No	No	2	4
424	2x64	7x31	npy_off	0	50	No	No	No	No	4	4
425	7x27	7x29	npy_off	0	50	No	No	No	No	1	3
426	4x39	I1x48	npy_off	0	50	No	No	No	No	2	6
427	2x61	7x35	npy_off	0	50	No	No	No	No	6	4
428	6x26	6x29	npy_off	0	50	Yes	No	No	No	4	6
429	3x26	4x65	npy_off	0	0	No	No	Yes	Yes	7	5
430	3x21	3x22	npy_off	0	50	No	No	No	No	8	3
431	1x60	8x56	npy_off	0	50	No	No	No	No	5	4
432	1x31	7x32	npy_off	0	25	No	No	No	No	4	2
433	1x35	1x39	npy_off	0	25	No	No	Yes	Yes	7	7
434	6x22	6x25	npy_off	0	25	No	No	No	No	3	3
435	7x26	7x30	npy_off	0	50	No	No	No	Yes	0	3
436	1x47	2x54	npy_off	0	0	No	No	No	No	7	7
437	6x24	6x27	npy_off	0	25	No	No	No	No	2	4
438	7x54	8x50	npy_off	0	25	No	No	Yes	Yes	7	8
439	7x54	8x54	npy_off	0	0	No	No	No	No	7	5
440	1x30	1x33	npy_off	0	0	No	No	No	No	2	6
441	5x42	5x46	npy_off	0	25	No	No	No	No	4	5
442	8x56	8x59	npy_off	0	0	No	No	No	No	4	0
443	5x36	5x37	npy_off	0	0	Yes	Yes	No	No	4	3
444	1x37	1x40	npy_off	0	0	No	No	No	No	5	5
445	3x23	3x24	npy_off	0	0	No	No	No	No	1	6
446	3x23	3x27	npy_off	0	0	No	No	No	No	1	5
447	6x57	6x58	npy_off	0	0	No	No	No	Yes	4	4
448	8x55	CT	npy_off	0	0	No	No	No	No	4	0

Orange: nodes, hubs and links specific of npy_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of npy_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	npy_on_gp Avg Int. Strength	npy_off Avg Int. Strength	npy_on_gp Num Of Links	npy_off Num Of Links	ConSurf
1	1x50	npy_on_gp	66.6667	0	4	3	9
2	1x53	npy_on_gp	0	0	4	2	9
3	I1x51	npy_on_gp	0	0	4	1	6
4	2x42	npy_on_gp	33.3333	50	4	2	7
5	2x50	npy_on_gp	100	0	5	3	9
6	2x53	npy_on_gp	33.3333	0	4	2	7
7	2x57	npy_on_gp	66.6667	0	6	3	7
8	3x43	npy_on_gp	66.6667	0	4	3	8
9	3x49	npy_on_gp	33.3333	25	4	3	8
10	3x51	npy_on_gp	33.3333	50	4	3	7
11	4x46	npy_on_gp	33.3333	0	4	1	7
12	4x50	npy_on_gp	66.6667	0	4	3	9
13	4x61	npy_on_gp	33.3333	50	4	3	5
14	E2x52	npy_on_gp	0	0	4	1	4
15	5x39	npy_on_gp	0	100	4	3	6
16	5x461	npy_on_gp	66.6667	0	4	2	6
17	5x58	npy_on_gp	100	0	7	3	9
18	5x64	npy_on_gp	0	0	4	3	5
19	6x26	npy_on_gp	33.3333	0	6	2	4
20	6x30	npy_on_gp	33.3333	50	6	2	7
21	6x59	npy_on_gp	66.6667	0	4	2	4
22	7x42	npy_on_gp	33.3333	0	4	2	7
23	7x49	npy_on_gp	33.3333	0	4	2	9
24	7x52	npy_on_gp	0	0	5	2	8
25	NT	Shared	33.3333	50	4	4	3
26	1x39	Shared	66.6667	75	5	5	7
27	2x40	Shared	33.3333	0	4	4	8
28	2x46	Shared	100	0	5	4	9
29	E1x50	Shared	100	100	6	4	8
30	E1x52	Shared	66.6667	0	6	4	7
31	3x32	Shared	66.6667	0	4	4	6
32	I2	Shared	66.6667	75	6	7	6
33	4x65	Shared	0	50	4	5	5
34	E2	Shared	100	100	16	11	3
35	5x36	Shared	33.3333	0	4	4	4
36	5x47	Shared	33.3333	50	4	4	8
37	6x44	Shared	33.3333	50	5	4	9
38	6x48	Shared	100	100	5	5	8
39	6x54	Shared	100	100	5	6	5
40	E3	Shared	66.6667	50	6	4	3
41	7x38	Shared	66.6667	75	4	5	6
42	7x53	Shared	66.6667	100	8	4	9
43	8x50	Shared	100	75	7	6	8
44	Lig	Shared	100	100	27	13	0
45	3x41	npy_off	0	25	2	4	7
46	3x50	npy_off	0	0	3	4	9
47	6x52	npy_off	33.3333	50	3	4	8
48	6x58	npy_off	0	25	3	4	4
49	7x30	npy_off	33.3333	50	3	5	3
50	7x47	npy_off	0	0	2	4	8

Orange: nodes, hubs and links specific of npy_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of npy_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	npy_on_gp Recurrence	npy_off Recurrence	npy_on_gp Hub1?	npy_off Hub1?	npy_on_gp Hub2?	npy_off Hub2?	ConSurf1	ConSurf2
1	Lig	NT	npy_on_gp	27.6901	0	Yes	Yes	Yes	Yes	0	3
2	2x64	Lig	npy_on_gp	10.6257	0	No	No	Yes	Yes	4	0
3	1x35	7x35	npy_on_gp	12.7661	0	No	No	No	No	7	4
4	1x39	2x57	npy_on_gp	22.8538	7.98287	Yes	Yes	Yes	No	7	7
5	7x38	7x42	npy_on_gp	11.7076	8.7769	Yes	Yes	Yes	No	6	7
6	2x57	7x42	npy_on_gp	16.2982	7.70233	Yes	No	Yes	No	7	7
7	2x46	2x50	npy_on_gp	31.7661	0	Yes	Yes	Yes	No	9	9
8	1x50	2x51	npy_on_gp	28.5673	0	Yes	No	No	No	9	8
9	3x43	7x49	npy_on_gp	11.7485	0	Yes	No	Yes	No	8	9
10	2x50	7x49	npy_on_gp	30.2632	0	Yes	No	Yes	No	9	9
11	2x54	2x57	npy_on_gp	40.8947	0	No	No	Yes	No	7	7
12	2x54	7x46	npy_on_gp	41.2982	5.74606	No	No	No	No	7	8
13	2x50	7x46	npy_on_gp	42.1871	6.88075	Yes	No	No	No	9	8
14	1x50	7x50	npy_on_gp	16.3918	4.60637	Yes	No	No	No	9	9
15	1x49	7x50	npy_on_gp	12.3099	3.46166	No	No	No	No	8	9
16	3x43	7x53	npy_on_gp	73.2105	0	Yes	No	Yes	Yes	8	9
17	2x43	7x53	npy_on_gp	60.4795	1.14971	No	No	Yes	Yes	8	9
18	1x53	2x43	npy_on_gp	12.4152	0	Yes	No	No	No	9	8
19	2x43	8x50	npy_on_gp	54.4912	0	No	No	Yes	Yes	8	8
20	1x57	8x50	npy_on_gp	10.6608	0	No	No	Yes	Yes	7	8
21	1x56	8x50	npy_on_gp	37.1988	2.29692	No	No	Yes	Yes	7	8
22	1x56	8x53	npy_on_gp	14.614	1.15472	No	No	No	No	7	5
23	1x56	8x54	npy_on_gp	21.2866	0	No	No	No	No	7	5
24	2x37	2x40	npy_on_gp	14.2398	2.31195	No	No	Yes	Yes	8	8
25	2x37	I1x51	npy_on_gp	12.2398	0	No	No	Yes	No	8	6
26	4x61	Lig	npy_on_gp	33.0936	8.09809	Yes	No	Yes	Yes	5	0
27	3x33	4x61	npy_on_gp	43.5789	2.337	No	No	Yes	No	4	5
28	3x33	4x57	npy_on_gp	43.386	1.16975	No	No	No	No	4	7
29	3x34	4x57	npy_on_gp	43.9649	0	No	No	No	No	5	7
30	3x34	4x50	npy_on_gp	45.1053	6.6503	No	No	Yes	No	5	9
31	4x46	4x50	npy_on_gp	40.7368	0	Yes	No	Yes	No	7	9
32	2x42	4x46	npy_on_gp	42.2047	0	Yes	No	Yes	No	7	7
33	2x42	3x49	npy_on_gp	100	0	Yes	No	Yes	No	7	8
34	3x46	7x53	npy_on_gp	66.8596	0	No	No	Yes	Yes	8	9
35	2x42	3x46	npy_on_gp	69.7719	3.31638	Yes	No	No	No	7	8
36	2x39	3x49	npy_on_gp	18.5614	0	No	No	Yes	No	7	8
37	2x39	2x40	npy_on_gp	17.848	0	No	No	Yes	Yes	7	8
38	5x461	Lig	npy_on_gp	13.1404	0	Yes	No	Yes	Yes	6	0
39	3x37	5x461	npy_on_gp	10.6667	3.09346	No	No	Yes	No	6	6
40	2x51	2x55	npy_on_gp	16.3918	1.15723	No	No	No	No	8	5
41	2x55	2x551	npy_on_gp	12.3099	0	No	No	No	No	5	5
42	2x63	Lig	npy_on_gp	12.8246	0	No	No	Yes	Yes	6	0
43	2x63	E1x50	npy_on_gp	10.9357	1.16474	No	No	Yes	Yes	6	8
44	E1x50	E1x52	npy_on_gp	21.6667	6.60772	Yes	Yes	Yes	Yes	8	7
45	E2	Lig	npy_on_gp	38.6901	0	Yes	Yes	Yes	Yes	3	0
46	E1x50	E2	npy_on_gp	14.883	0	Yes	Yes	Yes	Yes	8	3
47	4x61	4x65	npy_on_gp	10.2632	0	Yes	No	Yes	Yes	5	5
48	3x49	3x53	npy_on_gp	98.7485	1.11715	Yes	No	No	No	8	8
49	3x53	I2	npy_on_gp	96.5614	0	No	No	Yes	Yes	8	6
50	5x64	I2	npy_on_gp	73.6257	0	Yes	No	Yes	Yes	5	6
51	3x55	5x64	npy_on_gp	12.8713	6.45242	No	No	Yes	No	6	5
52	3x52	I2	npy_on_gp	14.4795	0.0601157	No	No	Yes	Yes	4	6
53	3x52	3x56	npy_on_gp	12.0175	1.05453	No	No	No	No	4	6
54	5x47	5x48	npy_on_gp	18.386	3.65454	Yes	Yes	No	No	8	5
55	5x45	5x48	npy_on_gp	16.5789	5.78864	No	No	No	No	5	5
56	5x42	5x45	npy_on_gp	14.7602	0	No	No	No	No	4	5
57	5x38	5x42	npy_on_gp	12.9298	1.4528	No	No	No	No	4	4
58	5x35	5x38	npy_on_gp	11.0877	0	No	No	No	No	3	4
59	6x54	7x37	npy_on_gp	10.0058	3.40906	Yes	Yes	No	No	5	6
60	5x51	6x44	npy_on_gp	19.8889	0	No	No	Yes	Yes	6	9
61	5x64	5x68	npy_on_gp	56.0117	4.2582	Yes	No	No	No	5	6
62	5x68	6x26	npy_on_gp	53.6374	0	No	No	Yes	No	6	4
63	6x26	6x30	npy_on_gp	32.1813	0	Yes	No	Yes	No	4	7
64	7x55	8x54	npy_on_gp	17.2807	0	No	No	No	No	6	5
65	7x55	8x51	npy_on_gp	12.9649	0	No	No	No	No	6	8
66	8x48	8x51	npy_on_gp	10.7895	1.11715	No	No	No	No	5	8
67	7x52	7x53	npy_on_gp	13.7836	0	Yes	No	Yes	Yes	8	9
68	6x48	7x45	npy_on_gp	15.269	7.15127	Yes	Yes	No	No	8	9
69	6x47	7x45	npy_on_gp	13.5497	6.14433	No	No	No	No	8	9
70	6x47	7x43	npy_on_gp	12.3918	5.13238	No	No	No	No	8	6
71	2x46	7x53	npy_on_gp	22.6901	0	Yes	Yes	Yes	Yes	9	9
72	7x49	7x53	npy_on_gp	19.7953	0	Yes	No	Yes	Yes	9	9
73	2x42	3x45	npy_on_gp	14.1579	2.2318	Yes	No	No	No	7	7
74	5x47	5x51	npy_on_gp	16.7076	1.48536	Yes	Yes	No	No	8	6
75	7x38	Lig	Shared	27.538	34.6166	Yes	Yes	Yes	Yes	6	0
76	1x39	7x38	Shared	15.4971	25.8823	Yes	Yes	Yes	Yes	7	6
77	3x36	Lig	Shared	89.807	47.286	No	No	Yes	Yes	7	0
78	3x36	6x48	Shared	94.9532	47.4213	No	No	Yes	Yes	7	8
79	6x44	6x48	Shared	83.5322	100	Yes	Yes	Yes	Yes	9	8
80	3x43	6x44	Shared	98.7135	61.288	Yes	No	Yes	Yes	8	9
81	2x46	3x43	Shared	14.0526	21.2684	Yes	Yes	Yes	No	9	8
82	1x50	2x50	Shared	46.807	42.4718	Yes	No	Yes	No	9	9
83	2x40	8x50	Shared	28.0234	17.0127	Yes	Yes	Yes	Yes	8	8
84	3x51	3x55	Shared	10.2398	34.4563	Yes	No	No	No	7	6
85	6x48	6x52	Shared	14.7427	54.6502	Yes	Yes	No	Yes	8	8
86	1x39	2x61	npy_off	2.4269	13.1553	Yes	Yes	No	No	7	6
87	4x65	Lig	npy_off	0	27.255	Yes	Yes	Yes	Yes	5	0
88	4x65	E2x50	npy_off	0	23.3099	Yes	Yes	No	No	5	9
89	3x25	E2x50	npy_off	0	14.0295	No	No	No	No	9	9
90	3x25	E2	npy_off	2.7076	13.5411	No	No	Yes	Yes	9	3
91	1x43	2x57	npy_off	6.23977	13.3883	No	No	Yes	No	7	7
92	6x52	Lig	npy_off	0	52.2155	No	Yes	Yes	Yes	8	0
93	2x50	3x39	npy_off	7.18713	49.0469	Yes	No	No	No	9	9
94	3x39	6x44	npy_off	0	50.898	No	No	Yes	Yes	9	9
95	1x50	2x47	npy_off	8.84211	37.6249	Yes	No	No	No	9	9
96	1x53	2x47	npy_off	8.35673	32.6529	Yes	No	No	No	9	9
97	2x40	7x53	npy_off	0	22.3155	Yes	Yes	Yes	Yes	8	9
98	1x53	7x53	npy_off	0	31.6359	Yes	No	Yes	Yes	9	9
99	2x38	3x49	npy_off	5.19883	10.7983	No	No	Yes	No	6	8
100	3x49	I2	npy_off	0	12.9349	Yes	No	Yes	Yes	8	6
101	3x56	I2	npy_off	0	25.7721	No	No	Yes	Yes	6	6
102	3x55	3x56	npy_off	0.163743	27.8186	No	No	No	No	6	6
103	3x51	5x61	npy_off	0	37.2893	Yes	No	No	No	7	8
104	5x61	6x34	npy_off	0	38.2186	No	No	No	No	8	6
105	3x50	6x34	npy_off	0	43.7167	No	Yes	No	No	9	6
106	3x50	6x37	npy_off	0	45.951	No	Yes	No	No	9	8
107	5x58	6x37	npy_off	2.46199	50.3619	Yes	No	No	No	9	8
108	3x47	5x58	npy_off	1.46199	53.786	No	No	Yes	No	9	9
109	3x47	5x54	npy_off	1.06433	54.6252	No	No	No	No	9	8
110	5x54	6x41	npy_off	0	58.5853	No	No	No	No	8	8
111	3x43	6x41	npy_off	0	60.1984	Yes	No	No	No	8	8
112	2x45	3x42	npy_off	6	14.8536	No	No	No	No	9	8
113	2x46	3x42	npy_off	6.90058	16.4792	Yes	Yes	No	No	9	8
114	2x46	3x39	npy_off	0	20.6272	Yes	Yes	No	No	9	9
115	2x45	4x50	npy_off	4.76023	11.5873	No	No	Yes	No	9	9
116	3x40	5x50	npy_off	9.84795	11.1289	No	No	No	No	7	9
117	3x40	6x44	npy_off	6.69591	12.1108	No	No	Yes	Yes	7	9
118	6x54	7x30	npy_off	7.62573	11.432	Yes	Yes	No	Yes	5	3
119	7x30	E3	npy_off	0.128655	14.6657	No	Yes	Yes	Yes	3	3
120	6x58	7x30	npy_off	0	11.1364	No	Yes	No	Yes	4	3
121	6x54	Lig	npy_off	0	16.2287	Yes	Yes	Yes	Yes	5	0
122	6x58	Lig	npy_off	9.36842	13.0752	No	Yes	Yes	Yes	4	0

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
NT	NT	npy_off	10.55	0	1	1	1	1
7x28	NT	npy_off	6.335	0	0	0	2	1
1x39	7x38	Shared	8.4375	5.08	0	0	2	1
2x56	3x32	Shared	6.4875	6.61667	0	1	2	1
2x60	3x28	npy_off	4.45	0	1	1	1	2
2x60	7x38	Shared	6.5025	13.69	1	1	1	1
2x63	E1x50	Shared	11.0925	10.29	0	1	1	2
2x64	7x35	Shared	4.79	3.96333	0	1	1	2
2x67	E2	npy_off	5.72	0	0	0	1	1
E1x49	E2	Shared	12.9575	9.77	0	1	2	1
3x25	E1x50	Shared	5.5475	6.96333	1	1	2	2
E1x50	E2x50	Shared	5.55	3.91667	1	1	2	2
3x22	E2	Shared	12.4425	8.92667	1	1	2	1
3x25	E2	Shared	5.255	2.72667	1	1	2	1
3x25	E2x50	Shared	7.28	6.06667	1	1	2	2
3x29	4x65	Shared	13.985	4.89667	0	0	2	1
3x32	7x38	npy_off	4.9425	0	1	1	1	1
3x32	Lig	Shared	8.4625	8.06	1	1	1	0
3x36	6x48	Shared	8.35	3.62333	0	1	1	2
3x36	Lig	Shared	8.465	2.52	0	1	1	0
3x37	5x461	Shared	11.2175	5.55333	0	0	2	1
4x60	5x39	Shared	18.4275	6.02667	0	0	2	1
4x61	5x39	Shared	7.245	6.81333	0	1	1	1
4x61	Lig	Shared	7.5075	2.94	0	1	1	0
4x64	E2	Shared	30.195	13.3033	1	1	2	1
4x65	E2x50	npy_off	4.3775	0	0	1	1	2
4x65	E2x52	Shared	5.195	5.68333	0	1	1	1
E2	E2	Shared	80.31	84.06	1	1	1	1
E2	E2x51	Shared	14.58	4.62667	1	1	1	1
5x36	E2	Shared	10.61	8.30667	1	1	1	1
5x35	E2	npy_off	16.2275	0	1	0	2	1
5x33	5x36	npy_off	4.17	0	1	0	2	1
5x33	E3	npy_off	5.3575	0	1	0	2	1
5x36	E3	npy_off	6.4875	0	1	1	1	1
5x39	5x43	npy_off	9.385	0	0	1	1	1
5x40	6x59	Shared	9.8225	7.25667	1	1	1	1
5x40	Lig	Shared	5.9625	6.93333	1	1	1	0
5x44	6x52	Shared	3.95	1.71667	0	0	2	1
5x47	6x52	Shared	8.645	6.85333	0	0	2	1
6x48	6x52	Shared	5.895	3.57667	0	1	2	1
6x51	6x55	Shared	7.4275	4.10333	0	0	2	1
6x51	7x34	npy_off	4.875	0	0	0	2	1
6x52	Lig	npy_off	10.6025	0	0	0	1	0
6x54	6x58	Shared	12.0625	2.42667	1	0	1	1
6x54	7x33	Shared	6.49	3.32667	1	0	1	2
6x54	7x34	Shared	8.5725	6.78667	1	0	1	1
6x54	7x37	Shared	4.2625	5.18667	1	0	1	2
6x54	Lig	npy_off	4.6875	0	1	0	1	0
6x55	Lig	Shared	18.185	14.26	0	1	1	0
6x58	7x30	npy_off	5.4375	0	1	1	1	1
6x58	Lig	Shared	3.9925	18.7733	1	1	1	0
6x59	Lig	Shared	6.89	7.15	1	1	1	0
6x61	E3	Shared	6.8775	9.83333	0	0	2	1
7x30	E3	Shared	4.845	4.04333	1	1	1	1
7x27	7x30	npy_off	9.09	0	0	1	1	1
7x34	Lig	Shared	10.6325	11.39	1	1	1	0
7x38	7x42	Shared	12.8025	8.75667	1	1	1	2
7x38	Lig	Shared	4.92	5.07333	1	1	1	0
E2	NT	npy_off	17.355	0	1	1	1	1
6x54	7x30	Shared	4.9225	2.81667	1	0	1	1
2x60	Lig	Shared	4.985	9.60333	1	1	1	0
4x65	Lig	npy_off	4.11	0	0	1	1	0
3x33	4x61	Shared	3.65	2.43333	0	0	2	1
2x53	3x32	npy_off	3.5825	0	0	1	2	1
3x41	5x461	npy_off	3.285	0	0	0	2	1
2x64	7x31	npy_off	2.195	0	0	1	1	1
7x27	7x29	npy_off	2.1925	0	0	1	1	2
3x26	4x65	npy_off	2.035	0	0	0	2	1
7x26	7x30	npy_off	1.725	0	0	0	2	1
5x36	5x37	npy_off	1.2125	0	1	1	1	2
6x57	6x58	npy_off	0.655	0	0	0	2	1
1x32	NT	npy_on_gp	0	3.32667	0	0	2	1
1x39	7x35	npy_on_gp	0	5.57333	0	0	2	2
2x53	2x56	npy_on_gp	0	2.81667	0	1	2	2
2x53	3x36	npy_on_gp	0	2.54333	0	1	2	1
2x56	7x42	npy_on_gp	0	2.7	0	1	2	2
2x60	3x32	npy_on_gp	0	2.83333	1	1	1	1
2x63	Lig	npy_on_gp	0	19.0333	0	1	1	0
2x67	Lig	npy_on_gp	0	8.3	0	0	1	0
E1x50	E2	npy_on_gp	0	3.25333	1	1	2	1
3x22	3x26	npy_on_gp	0	3.6	1	1	2	2
3x28	3x32	npy_on_gp	0	2.75333	0	0	2	1
E2	E2x50	npy_on_gp	0	4.53333	1	1	1	2
E2	Lig	npy_on_gp	0	42.4667	1	1	1	0
E2x51	Lig	npy_on_gp	0	7.28667	0	1	1	0
E2	E2x52	npy_on_gp	0	6.97667	1	1	1	1
5x39	E2	npy_on_gp	0	3.23667	0	1	1	1
5x36	6x59	npy_on_gp	0	6.35333	1	1	1	1
5x36	Lig	npy_on_gp	0	5.18333	1	1	1	0
5x43	5x461	npy_on_gp	0	8.15667	0	1	1	1
5x43	Lig	npy_on_gp	0	5.10667	0	1	1	0
5x461	Lig	npy_on_gp	0	4.14333	0	1	1	0
6x58	6x59	npy_on_gp	0	2.61667	1	1	1	1
7x30	Lig	npy_on_gp	0	7.68	1	1	1	0
7x31	Lig	npy_on_gp	0	11.0133	0	0	1	0
Lig	NT	npy_on_gp	0	3.18667	1	1	0	1
E3	Lig	npy_on_gp	0	10.41	1	1	1	0
E2x52	Lig	npy_on_gp	0	5.04	0	1	1	0
2x64	Lig	npy_on_gp	0	2.52333	0	1	1	0
5x39	Lig	npy_on_gp	0	3.41667	0	1	1	0
7x29	NT	npy_on_gp	0	3.35333	0	0	2	1
2x53	7x42	npy_on_gp	0	2.91333	0	1	2	2
2x63	E2	npy_on_gp	0	3.43667	0	1	1	1
3x28	E1x50	npy_on_gp	0	2.45667	0	0	2	2
4x61	4x65	npy_on_gp	0	2.64333	0	1	1	1
4x65	E2	npy_on_gp	0	2.88333	0	1	1	1
5x36	E2x52	npy_on_gp	0	3.49	1	1	1	1
E3	E3	npy_on_gp	0	3.59333	1	1	1	1
7x27	Lig	npy_on_gp	0	2.21	0	1	1	0
7x28	7x29	npy_on_gp	0	1.84	0	0	2	2
5x46	5x461	npy_on_gp	0	1.83667	0	0	2	1
1x31	NT	npy_on_gp	0	1.41333	0	0	2	1
5x33	E2	npy_on_gp	0	1.03333	1	0	2	1
7x26	7x27	npy_on_gp	0	0.903333	0	0	2	1
6x57	E3	npy_on_gp	0	0.513333	0	0	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	npy_on_gp	npy1_on_gp npy2_on_gp npy4_on_gp
	npy_off	npy1_off npy2_off

Network Difference
Value	npy_on_gp	npy_off
I_min	2.28667	3.805
Number of Linked Nodes	271	260
Number of Specific Nodes	11 (4.06%)	0 (0.00%)
Number of Shared Nodes	260 (95.94%)	260 (100.00%)
Number of Links	337	280
Number of Specific Links	168 (49.85%)	111 (39.64%)
Number of Shared Links	169 (50.15%)	169 (60.36%)
Number of Hubs	44	26
Number of Specific Hubs	24 (54.55%)	6 (23.08%)
Number of Shared Hubs	20 (45.45%)	20 (76.92%)
Average % Shared Neighbours (Jaccard)	43.28
Average % Shared Neighbours (Otsuka)	53.29
Average % Shared Neighbours (Overlap Coefficient)	63.16
Average % Shared Cliques (k3-6)	51.67
Graphlets Similarity	0.520421

Paths Difference
Value	npy_on_gp	npy_off
Number Of Nodes in MetaPath	80	47
Specific Nodes in MetaPath	55 (68.75%)	22 (46.81%)
Shared Nodes in MetaPath	260 (95.94%)	260 (95.94%)
Number Of Links MetaPath	85	48
Specific Links in MetaPath	74 (87.06%)	37 (77.08%)
Shared Links in MetaPath	169 (50.15%)	169 (50.15%)
Number of Shortest Paths	60960	62980
Length Of Smallest Path	3	3
Average Path Length	11.4216	14.7901
Length of Longest Path	27	35
Minimum Path Strength	0.456667	0.745
Average Path Strength	4.56366	5.85599
Maximum Path Strength	28.3633	23.775
Minimum Path Correlation	0.703333	0.7
Average Path Correlation	0.932492	0.924132
Maximum Path Correlation	0.99	0.99
Minimum % Of Corr. Nodes	4.7619	3.57143
Average % Of Corr. Nodes	57.8436	48.4826
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	49.445	36.3871
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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