psnGPCR

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Orange: nodes, hubs and links specific of nts1_off_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of nts1_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	nts1_off_allo Int. Strength	nts1_off Int. Strength	nts1_off_allo Hub1?	nts1_off Hub1?	nts1_off_allo Hub2?	nts1_off Hub2?	ConSurf1	ConSurf2
1	1x30	1x34	nts1_off_allo	4.69	0	No	No	No	No	2	5
2	1x32	2x66	nts1_off_allo	13.92	0	No	No	Yes	No	5	5
3	1x32	E1	nts1_off_allo	5.24	0	No	No	No	No	5	4
4	1x36	2x61	nts1_off_allo	4.42	0	No	No	No	No	6	6
5	1x45	7x47	nts1_off_allo	3.17	0	No	No	No	No	6	7
6	1x50	2x47	nts1_off_allo	4.69	0	Yes	No	No	No	9	9
7	1x52	8x54	nts1_off_allo	10.49	0	Yes	No	Yes	No	6	7
8	1x52	8x57	nts1_off_allo	3.17	0	Yes	No	Yes	No	6	5
9	1x52	8x58	nts1_off_allo	4.47	0	Yes	No	No	No	6	7
10	1x53	7x50	nts1_off_allo	3.5	0	No	No	Yes	No	9	9
11	1x56	8x50	nts1_off_allo	3.89	0	Yes	No	Yes	No	7	8
12	1x56	8x53	nts1_off_allo	3.04	0	Yes	No	No	No	7	6
13	1x56	8x54	nts1_off_allo	5.19	0	Yes	No	Yes	No	7	7
14	1x56	8x57	nts1_off_allo	4.71	0	Yes	No	Yes	No	7	5
15	1x59	8x53	nts1_off_allo	13.78	0	No	No	No	No	5	6
16	1x59	8x57	nts1_off_allo	6.47	0	No	No	Yes	No	5	5
17	2x37	2x41	nts1_off_allo	3.82	0	No	No	Yes	No	8	5
18	2x41	4x42	nts1_off_allo	7.49	0	Yes	No	No	No	5	7
19	2x41	4x43	nts1_off_allo	5.97	0	Yes	No	No	No	5	3
20	2x46	7x49	nts1_off_allo	4.12	0	No	No	Yes	Yes	9	9
21	2x49	3x35	nts1_off_allo	3.44	0	Yes	No	No	No	8	7
22	2x49	3x38	nts1_off_allo	3.42	0	Yes	No	No	No	8	7
23	2x49	Na	nts1_off_allo	5.94	0	Yes	No	No	No	8	0
24	2x50	Na	nts1_off_allo	10.74	0	No	No	No	No	9	0
25	2x53	7x46	nts1_off_allo	4.8	0	No	No	No	No	7	9
26	2x54	7x46	nts1_off_allo	3	0	No	No	No	No	7	9
27	2x60	2x65	nts1_off_allo	4.1	0	Yes	Yes	No	No	6	4
28	2x63	2x67	nts1_off_allo	2.96	0	Yes	No	No	No	5	5
29	2x64	3x28	nts1_off_allo	7.22	0	No	Yes	Yes	Yes	4	6
30	2x65	2x66	nts1_off_allo	8.22	0	No	No	Yes	No	4	5
31	E1	E1x49	nts1_off_allo	7.63	0	No	No	No	No	4	5
32	E1	E2	nts1_off_allo	8.46	0	No	No	Yes	Yes	4	3
33	3x21	E2	nts1_off_allo	3.27	0	No	No	Yes	Yes	8	3
34	3x31	3x35	nts1_off_allo	3.17	0	No	No	No	No	5	7
35	3x39	Na	nts1_off_allo	8.75	0	No	Yes	No	No	9	0
36	3x44	5x54	nts1_off_allo	3.25	0	No	No	No	No	8	8
37	3x49	3x50	nts1_off_allo	13.96	0	Yes	Yes	Yes	No	8	9
38	3x51	3x52	nts1_off_allo	3.52	0	Yes	Yes	Yes	No	8	4
39	3x51	5x61	nts1_off_allo	3.59	0	Yes	Yes	No	No	8	9
40	3x52	3x56	nts1_off_allo	5.14	0	Yes	No	Yes	No	4	6
41	3x54	3x55	nts1_off_allo	3.27	0	No	Yes	Yes	No	9	7
42	3x54	6x34	nts1_off_allo	6.08	0	No	Yes	No	No	9	7
43	I2x52	I2x55	nts1_off_allo	4.5	0	No	No	No	No	4	4
44	4x39	4x43	nts1_off_allo	3.71	0	No	No	No	No	3	3
45	4x41	4x44	nts1_off_allo	3.71	0	No	No	No	No	5	4
46	4x42	4x46	nts1_off_allo	3.04	0	No	No	No	No	7	7
47	4x45	4x49	nts1_off_allo	5.02	0	No	No	Yes	No	6	7
48	4x51	4x55	nts1_off_allo	4.15	0	No	No	No	No	3	4
49	4x64	4x65	nts1_off_allo	4.52	0	Yes	No	No	No	5	6
50	4x64	E2	nts1_off_allo	3.04	0	Yes	No	Yes	Yes	5	3
51	5x36	E2	nts1_off_allo	3.07	0	No	No	Yes	Yes	5	3
52	5x40	6x59	nts1_off_allo	3.27	0	No	No	Yes	No	6	3
53	5x47	6x44	nts1_off_allo	4.29	0	Yes	Yes	No	Yes	8	9
54	5x54	6x41	nts1_off_allo	3.07	0	No	No	No	No	8	8
55	5x58	5x61	nts1_off_allo	8.38	0	Yes	No	No	No	9	9
56	5x60	5x64	nts1_off_allo	6.07	0	No	No	No	No	5	5
57	5x63	5x64	nts1_off_allo	3.64	0	No	No	No	No	4	5
58	5x65	6x31	nts1_off_allo	4.86	0	No	No	No	No	8	5
59	5x67	5x68	nts1_off_allo	3.23	0	No	No	No	No	4	6
60	5x68	5x71	nts1_off_allo	4.47	0	No	No	No	No	6	7
61	5x70	6x27	nts1_off_allo	5.43	0	No	No	No	No	4	3
62	5x71	6x27	nts1_off_allo	5.43	0	No	No	No	No	7	3
63	5x71	6x31	nts1_off_allo	4.86	0	No	No	No	No	7	5
64	5x72	6x26	nts1_off_allo	7.65	0	No	No	No	Yes	5	4
65	5x74	5x76	nts1_off_allo	5.75	0	No	No	No	No	5	2
66	5x75	5x76	nts1_off_allo	3.49	0	No	No	No	No	4	2
67	6x28	6x29	nts1_off_allo	3.62	0	No	No	No	No	5	6
68	6x29	6x32	nts1_off_allo	4.82	0	No	No	No	Yes	6	8
69	6x36	7x56	nts1_off_allo	7.45	0	No	No	No	No	8	7
70	6x43	7x48	nts1_off_allo	3.25	0	No	No	No	No	7	6
71	6x54	6x55	nts1_off_allo	4.26	0	Yes	Yes	Yes	Yes	5	6
72	6x57	6x61	nts1_off_allo	4.37	0	Yes	No	No	No	4	3
73	7x27	E3	nts1_off_allo	5.79	0	No	No	No	Yes	2	3
74	E3	Lig	nts1_off_allo	6.68	0	No	Yes	Yes	Yes	3	0
75	7x23	7x24	nts1_off_allo	5.25	0	No	No	No	No	4	4
76	7x28	7x32	nts1_off_allo	3.45	0	No	No	No	No	1	1
77	7x31	7x32	nts1_off_allo	3.27	0	No	No	No	No	4	1
78	7x33	7x37	nts1_off_allo	5.19	0	No	No	No	No	4	6
79	7x49	7x50	nts1_off_allo	3.26	0	Yes	Yes	Yes	No	9	9
80	7x53	8x50	nts1_off_allo	10.32	0	Yes	Yes	Yes	No	9	8
81	7x54	8x50	nts1_off_allo	8.46	0	No	No	Yes	No	7	8
82	7x54	8x51	nts1_off_allo	3.62	0	No	No	No	No	7	9
83	7x54	8x54	nts1_off_allo	15.71	0	No	No	Yes	No	7	7
84	8x47	8x49	nts1_off_allo	7.45	0	No	No	No	No	8	7
85	8x50	8x54	nts1_off_allo	11.79	0	Yes	No	Yes	No	8	7
86	8x51	8x55	nts1_off_allo	4.86	0	No	No	No	No	9	4
87	8x54	8x58	nts1_off_allo	4.87	0	Yes	No	No	No	7	7
88	1x51	2x51	nts1_off_allo	2.95	0	No	No	No	Yes	4	7
89	5x32	5x34	nts1_off_allo	2.93	0	No	No	No	No	4	1
90	2x39	3x49	nts1_off_allo	2.85	0	No	No	Yes	Yes	8	8
91	3x55	5x64	nts1_off_allo	2.79	0	Yes	No	No	No	7	5
92	3x40	6x44	nts1_off_allo	2.77	0	No	No	No	Yes	8	9
93	3x50	3x53	nts1_off_allo	2.77	0	Yes	No	No	No	9	8
94	3x52	I2x56	nts1_off_allo	2.77	0	Yes	No	No	No	4	4
95	8x47	8x50	nts1_off_allo	2.64	0	No	No	Yes	No	8	8
96	3x47	5x58	nts1_off_allo	2.54	0	No	No	Yes	No	9	9
97	1x33	2x66	nts1_off_allo	2.45	0	No	No	Yes	No	6	5
98	1x43	2x55	nts1_off_allo	2.44	0	No	No	No	No	7	5
99	7x25	7x26	nts1_off_allo	2.44	0	No	No	No	No	2	1
100	6x36	7x53	nts1_off_allo	2.34	0	No	No	Yes	Yes	8	9
101	5x76	6x28	nts1_off_allo	2.33	0	No	No	No	No	2	5
102	7x27	7x28	nts1_off_allo	2.3	0	No	No	No	No	2	1
103	2x52	4x50	nts1_off_allo	2.28	0	No	No	Yes	Yes	8	9
104	5x72	5x73	nts1_off_allo	1.86	0	No	No	No	No	5	4
105	1x54	2x44	nts1_off_allo	1.71	0	No	No	No	No	8	6
106	1x57	2x44	nts1_off_allo	1.71	0	No	No	No	No	7	6
107	5x70	5x73	nts1_off_allo	1.71	0	No	No	No	No	4	4
108	6x47	7x43	nts1_off_allo	1.71	0	No	No	No	No	9	5
109	3x44	5x53	nts1_off_allo	1.7	0	No	No	No	No	8	6
110	I2x53	I2x57	nts1_off_allo	1.61	0	No	No	No	No	6	7
111	3x43	6x40	nts1_off_allo	1.6	0	No	No	No	No	8	8
112	3x43	6x41	nts1_off_allo	1.6	0	No	No	No	No	8	8
113	2x56	3x31	nts1_off_allo	1.58	0	No	No	No	No	7	5
114	3x53	6x30	nts1_off_allo	1.58	0	No	No	No	No	8	7
115	3x56	I2x50	nts1_off_allo	1.53	0	Yes	No	No	No	6	8
116	5x74	6x26	nts1_off_allo	1.53	0	No	No	No	Yes	5	4
117	5x44	5x48	nts1_off_allo	1.52	0	No	No	No	No	6	5
118	6x53	6x57	nts1_off_allo	1.52	0	No	No	Yes	No	5	4
119	3x27	3x30	nts1_off_allo	1.51	0	No	No	Yes	No	5	6
120	5x72	6x30	nts1_off_allo	1.5	0	No	No	No	No	5	7
121	3x48	5x57	nts1_off_allo	1.49	0	No	No	No	No	7	7
122	5x59	5x60	nts1_off_allo	1.47	0	No	No	No	No	3	5
123	5x59	5x63	nts1_off_allo	1.47	0	No	No	No	No	3	4
124	8x48	8x52	nts1_off_allo	1.46	0	No	No	No	No	4	4
125	5x62	5x66	nts1_off_allo	1.45	0	No	No	No	No	6	5
126	7x51	7x55	nts1_off_allo	1.43	0	No	No	No	No	6	6
127	1x54	2x48	nts1_off_allo	1.38	0	No	No	No	No	8	6
128	1x59	8x56	nts1_off_allo	1.38	0	No	No	No	No	5	4
129	5x32	5x35	nts1_off_allo	1.37	0	No	No	No	No	4	4
130	1x51	1x55	nts1_off_allo	1.3	0	No	No	No	No	4	4
131	1x55	8x57	nts1_off_allo	1.3	0	No	No	Yes	No	4	5
132	1x30	1x33	nts1_off_allo	1.26	0	No	No	No	No	2	6
133	1x38	1x39	nts1_off_allo	1.26	0	No	No	Yes	Yes	4	7
134	1x35	1x39	Shared	5.05	3.79	No	No	Yes	Yes	5	7
135	1x36	2x66	Shared	9.7	12.13	No	No	Yes	No	6	5
136	1x39	2x57	Shared	8.38	4.69	Yes	Yes	Yes	Yes	7	8
137	1x39	2x60	Shared	6.73	5.625	Yes	Yes	Yes	Yes	7	6
138	1x39	2x61	Shared	4.69	5.275	Yes	Yes	No	No	7	6
139	1x39	7x42	Shared	8.94	5.96	Yes	Yes	Yes	Yes	7	7
140	1x42	7x43	Shared	2.98	4.47	No	No	No	No	7	5
141	1x43	1x47	Shared	7.78	7.78	No	No	No	No	7	6
142	1x46	7x47	Shared	3.64	1.95	No	No	No	No	8	7
143	1x49	7x50	Shared	4.06	2.03	No	No	Yes	No	9	9
144	1x50	2x50	Shared	12.12	10.095	Yes	No	No	No	9	9
145	1x50	2x51	Shared	4.12	3.435	Yes	No	No	Yes	9	7
146	1x50	7x50	Shared	6.52	12.215	Yes	No	Yes	No	9	9
147	1x52	1x56	Shared	4.76	1.59	Yes	No	Yes	No	6	7
148	1x54	2x47	Shared	3.15	3.15	No	No	No	No	8	9
149	1x57	2x40	Shared	7.71	4.75	No	No	No	No	7	8
150	2x37	4x39	Shared	5.27	6.585	No	No	No	No	8	3
151	2x38	3x49	Shared	4.23	6.975	No	Yes	Yes	Yes	7	8
152	2x41	4x39	Shared	7.2	8.745	Yes	No	No	No	5	3
153	2x42	3x45	Shared	6.97	7.63	No	Yes	No	No	8	7
154	2x42	3x46	Shared	12.86	11.72	No	Yes	No	No	8	9
155	2x43	7x53	Shared	15.24	8.795	No	No	Yes	Yes	8	9
156	2x45	3x42	Shared	8.94	8.94	No	No	No	No	9	8
157	2x45	4x46	Shared	3.1	3.1	No	No	No	No	9	7
158	2x45	4x50	Shared	6.18	6.18	No	No	Yes	Yes	9	9
159	2x46	3x42	Shared	5.49	7.555	No	No	No	No	9	8
160	2x49	3x39	Shared	4.8	4	Yes	No	No	Yes	8	9
161	2x49	4x50	Shared	3.71	4.94	Yes	No	Yes	Yes	8	9
162	2x50	7x46	Shared	7.36	5.26	No	No	No	No	9	9
163	2x53	3x35	Shared	3.38	6.55	No	No	No	No	7	7
164	2x53	7x41	Shared	3.89	3.28	No	No	Yes	Yes	7	7
165	2x57	2x58	Shared	3.35	5.75	Yes	Yes	No	No	8	9
166	2x57	7x42	Shared	16.76	10.55	Yes	Yes	Yes	Yes	8	7
167	2x59	E1x52	Shared	3.93	9.835	No	No	Yes	Yes	6	7
168	2x59	3x28	Shared	7.57	9.465	No	No	Yes	Yes	6	6
169	2x60	3x32	Shared	4.65	3.505	Yes	Yes	No	Yes	6	7
170	2x60	7x38	Shared	3.94	8.625	Yes	Yes	No	Yes	6	6
171	2x60	7x42	Shared	10.1	13.6	Yes	Yes	Yes	Yes	6	7
172	2x62	2x63	Shared	8.14	8.14	Yes	Yes	Yes	No	5	5
173	2x62	2x67	Shared	6.31	12.62	Yes	Yes	No	No	5	5
174	2x62	E1x52	Shared	6.19	4.64	Yes	Yes	Yes	Yes	5	7
175	2x63	E1x50	Shared	14.69	11.865	Yes	No	Yes	Yes	5	8
176	2x63	E1x52	Shared	9.67	8.46	Yes	No	Yes	Yes	5	7
177	E1x50	E1x52	Shared	12.03	11.525	Yes	Yes	Yes	Yes	8	7
178	3x25	E1x50	Shared	3.92	4.57	No	No	Yes	Yes	9	8
179	E1x50	E2x50	Shared	6.53	13.06	Yes	Yes	No	No	8	9
180	3x22	3x26	Shared	10.72	10.37	No	No	No	No	3	7
181	3x22	E2	Shared	8.18	8.785	No	No	Yes	Yes	3	3
182	3x25	E2x50	Shared	7.28	7.28	No	No	No	No	9	9
183	3x28	3x29	Shared	12.91	13.405	Yes	Yes	No	Yes	6	4
184	3x28	3x32	Shared	13.38	10.29	Yes	Yes	No	Yes	6	7
185	3x29	4x61	Shared	3.59	2.995	No	Yes	No	No	4	5
186	3x29	4x65	Shared	10.78	12.575	No	Yes	No	No	4	6
187	3x30	4x62	Shared	10.96	10.96	Yes	No	No	No	6	5
188	3x32	7x41	Shared	17.1	13.185	No	Yes	Yes	Yes	7	7
189	3x33	4x61	Shared	8.32	8.2	No	Yes	No	No	5	5
190	3x36	5x461	Shared	3.2	3.2	No	No	Yes	Yes	7	6
191	3x36	6x48	Shared	4.85	4.245	No	No	Yes	Yes	7	8
192	3x37	4x56	Shared	17.58	15.235	Yes	Yes	No	No	7	6
193	3x37	5x43	Shared	9.3	6.98	Yes	Yes	No	Yes	7	6
194	3x37	5x46	Shared	3.59	5.985	Yes	Yes	No	No	7	5
195	3x37	5x461	Shared	3.82	6.995	Yes	Yes	Yes	Yes	7	6
196	3x38	4x50	Shared	3.89	7.78	No	No	Yes	Yes	7	9
197	3x38	4x53	Shared	3.42	3.42	No	No	No	No	7	8
198	3x45	4x45	Shared	5.28	3.3	No	No	No	No	7	6
199	3x45	4x49	Shared	3.1	3.87	No	No	Yes	No	7	7
200	3x46	6x37	Shared	2.98	4.155	No	No	No	Yes	9	8
201	3x47	5x54	Shared	6.19	3.42	No	No	No	No	9	8
202	3x49	I2x57	Shared	10.83	10.83	Yes	Yes	No	No	8	7
203	3x50	6x33	Shared	8.77	3.42	Yes	No	No	No	9	8
204	3x50	6x34	Shared	3.88	2.98	Yes	No	No	No	9	7
205	3x50	6x37	Shared	5.23	3.46	Yes	No	No	Yes	9	8
206	3x51	3x55	Shared	6.72	9.41	Yes	Yes	Yes	No	8	7
207	3x51	3x56	Shared	4.36	4.355	Yes	Yes	Yes	No	8	6
208	3x51	5x57	Shared	15.24	11.72	Yes	Yes	No	No	8	7
209	3x52	I2x57	Shared	4.24	2.12	Yes	No	No	No	4	7
210	3x54	5x61	Shared	4.37	2.435	No	Yes	No	No	9	9
211	3x55	3x56	Shared	4.42	4.42	Yes	No	Yes	No	7	6
212	I2x52	I2x56	Shared	7.05	5.64	No	No	No	No	4	4
213	4x40	4x44	Shared	3.06	2.295	No	No	No	No	4	4
214	4x59	4x60	Shared	3.53	3.39	No	Yes	No	No	5	7
215	4x59	4x62	Shared	2.98	2.855	No	Yes	No	No	5	5
216	4x61	4x64	Shared	7.53	4.52	No	No	Yes	No	5	5
217	4x64	5x39	Shared	3.17	3.175	Yes	No	No	No	5	6
218	4x65	E2x52	Shared	8.39	5.87	No	No	No	Yes	6	5
219	E2	E2	Shared	69.89	22.57	Yes	Yes	Yes	Yes	3	3
220	E2	E2x51	Shared	7.42	13.18	Yes	Yes	No	No	3	4
221	E2x51	E2x52	Shared	6.99	5.25	No	No	No	Yes	4	5
222	5x35	E2	Shared	7.6	8.165	No	No	Yes	Yes	4	3
223	5x37	6x59	Shared	6.47	4.58	No	No	Yes	No	4	3
224	5x40	6x55	Shared	7.52	5.01	No	No	Yes	Yes	6	6
225	5x40	Lig	Shared	4.65	4.145	No	No	Yes	Yes	6	0
226	5x41	6x59	Shared	7.63	6.445	No	No	Yes	No	5	3
227	5x41	6x60	Shared	9.02	9.58	No	No	No	No	5	5
228	5x43	5x461	Shared	7.45	6.705	No	Yes	Yes	Yes	6	6
229	5x43	6x55	Shared	6.03	5.425	No	Yes	Yes	Yes	6	6
230	5x44	6x52	Shared	6.85	11.635	No	No	No	Yes	6	7
231	5x45	5x48	Shared	6.28	4.87	No	No	No	No	5	5
232	5x461	6x52	Shared	4.18	3.485	Yes	Yes	No	Yes	6	7
233	5x47	5x51	Shared	8.71	3.73	Yes	Yes	No	No	8	6
234	5x47	6x49	Shared	7.31	5.48	Yes	Yes	No	No	8	7
235	5x47	6x52	Shared	15.84	20.93	Yes	Yes	No	Yes	8	7
236	5x49	5x50	Shared	4.33	2.885	No	No	No	No	6	9
237	5x51	6x45	Shared	3.04	3.04	No	No	No	No	6	7
238	5x58	6x37	Shared	3.79	10.985	Yes	No	No	Yes	9	8
239	5x58	6x38	Shared	11.72	11.45	Yes	No	No	No	9	5
240	6x27	6x31	Shared	11.91	3.27	No	No	No	No	3	5
241	6x40	7x49	Shared	2.96	5.175	No	No	Yes	Yes	8	9
242	6x44	6x48	Shared	12.03	9.02	No	Yes	Yes	Yes	9	8
243	6x47	7x45	Shared	3.44	6.025	No	No	No	Yes	9	9
244	6x48	7x41	Shared	4.01	15.035	Yes	Yes	Yes	Yes	8	7
245	6x48	7x45	Shared	9.88	3.09	Yes	Yes	No	Yes	8	9
246	6x49	6x50	Shared	3.28	4.105	No	No	No	No	7	9
247	6x50	7x40	Shared	3.28	4.105	No	No	No	No	9	7
248	6x51	6x54	Shared	3.09	7.715	No	Yes	Yes	Yes	6	5
249	6x51	6x55	Shared	10.29	10.805	No	Yes	Yes	Yes	6	6
250	6x54	7x34	Shared	12.35	15.95	Yes	Yes	No	Yes	5	4
251	6x54	7x37	Shared	11.64	9.225	Yes	Yes	No	No	5	6
252	6x54	7x38	Shared	6.03	9.04	Yes	Yes	No	Yes	5	6
253	6x54	Lig	Shared	12.67	10.645	Yes	Yes	Yes	Yes	5	0
254	6x57	7x33	Shared	7.46	4.975	Yes	No	No	No	4	4
255	6x57	Lig	Shared	8.29	10.43	Yes	No	Yes	Yes	4	0
256	6x58	Lig	Shared	30.17	20.055	No	No	Yes	Yes	4	0
257	6x59	6x60	Shared	4.03	12.62	Yes	No	No	No	3	5
258	7x30	E3	Shared	13.5	4.34	Yes	Yes	No	Yes	4	3
259	7x23	7x26	Shared	4.42	1.475	No	No	No	No	4	1
260	7x26	7x30	Shared	4.69	5.86	No	No	Yes	Yes	1	4
261	7x27	Lig	Shared	3.06	2.755	No	No	Yes	Yes	2	0
262	7x29	7x30	Shared	6.19	4.125	No	No	Yes	Yes	4	4
263	7x30	Lig	Shared	8.41	14.32	Yes	Yes	Yes	Yes	4	0
264	7x31	7x35	Shared	6.57	7.88	No	No	No	No	4	3
265	7x34	7x38	Shared	5.81	4.65	No	Yes	No	Yes	4	6
266	7x34	Lig	Shared	12.99	17.775	No	Yes	Yes	Yes	4	0
267	7x41	7x42	Shared	10.32	4.125	Yes	Yes	Yes	Yes	7	7
268	7x48	7x52	Shared	5.71	6.425	No	No	No	No	6	8
269	7x49	7x53	Shared	9.3	2.905	Yes	Yes	Yes	Yes	9	9
270	1x53	1x57	Shared	2.95	2.95	No	No	No	No	9	7
271	5x44	6x56	Shared	2.95	5.16	No	No	No	No	6	6
272	3x41	4x49	Shared	2.85	4.995	No	No	Yes	No	6	7
273	6x38	6x42	Shared	2.85	1.88	No	No	No	No	5	5
274	3x42	4x49	Shared	2.83	7.08	No	No	Yes	No	8	7
275	2x551	3x31	Shared	2.77	7.92	No	No	No	No	5	5
276	3x30	4x57	Shared	2.77	4.16	Yes	No	No	No	6	7
277	2x62	E1x51	Shared	2.67	0.665	Yes	Yes	No	No	5	3
278	4x38	4x41	Shared	2.64	5.93	No	No	No	No	8	5
279	4x59	4x63	Shared	2.62	1.26	No	Yes	No	No	5	4
280	1x43	2x57	Shared	2.49	3.045	No	No	Yes	Yes	7	8
281	3x23	3x24	Shared	1.95	0.975	No	No	No	No	1	6
282	3x40	5x50	Shared	1.87	3.74	No	No	No	No	8	9
283	1x48	1x49	Shared	1.84	2.76	No	No	No	No	5	9
284	3x34	4x57	Shared	1.79	1.79	No	No	No	No	6	7
285	1x46	2x54	Shared	1.71	1.71	No	No	No	No	8	7
286	5x38	5x42	Shared	1.6	1.49	No	No	No	No	4	5
287	1x45	7x51	Shared	1.54	1.54	No	No	No	No	6	6
288	3x33	4x57	Shared	1.54	3.825	No	Yes	No	No	5	7
289	1x31	1x32	Shared	1.53	0.765	No	No	No	No	3	5
290	3x24	E1x52	Shared	1.51	1.51	No	No	Yes	Yes	6	7
291	5x33	5x37	Shared	1.5	5.82	No	No	No	No	4	4
292	7x36	7x40	Shared	1.49	1.385	No	No	No	No	6	7
293	1x36	1x40	Shared	1.47	2.21	No	No	No	No	6	5
294	7x48	7x49	Shared	1.42	2.125	No	No	Yes	Yes	6	9
295	3x30	4x54	Shared	1.39	0.695	Yes	No	No	No	6	4
296	1x39	7x39	Shared	1.33	4	Yes	Yes	No	No	7	5
297	1x35	2x65	nts1_off	0	4.61	No	No	No	No	5	4
298	1x39	2x65	nts1_off	0	4.23	Yes	Yes	No	No	7	4
299	1x42	7x47	nts1_off	0	3.15	No	No	No	No	7	7
300	1x47	2x51	nts1_off	0	3.685	No	No	No	Yes	6	7
301	1x47	2x55	nts1_off	0	4.425	No	No	No	No	6	5
302	1x53	2x47	nts1_off	0	3.36	No	No	No	No	9	9
303	1x60	2x40	nts1_off	0	11.75	No	No	No	No	0	8
304	2x36	I1	nts1_off	0	5.78	No	Yes	No	No	0	0
305	2x37	I1	nts1_off	0	4.075	No	No	No	No	8	0
306	2x33	2x36	nts1_off	0	3.2	No	Yes	No	Yes	0	0
307	2x33	6x29	nts1_off	0	3.03	No	Yes	No	No	0	6
308	2x33	6x32	nts1_off	0	2.92	No	Yes	No	Yes	0	8
309	2x34	2x38	nts1_off	0	5.93	No	No	No	Yes	0	7
310	2x34	4x39	nts1_off	0	4.615	No	No	No	No	0	3
311	2x35	2x38	nts1_off	0	6.68	No	No	No	Yes	0	7
312	2x35	6x29	nts1_off	0	3.94	No	No	No	No	0	6
313	2x35	6x30	nts1_off	0	3.46	No	No	No	No	0	7
314	2x36	6x32	nts1_off	0	12.27	No	Yes	No	Yes	0	8
315	2x38	I2x57	nts1_off	0	6.825	No	Yes	No	No	7	7
316	2x38	4x42	nts1_off	0	11.645	No	Yes	No	No	7	7
317	2x42	3x49	nts1_off	0	12.91	No	Yes	Yes	Yes	8	8
318	2x42	4x42	nts1_off	0	4.995	No	Yes	No	No	8	7
319	2x42	4x46	nts1_off	0	6.045	No	Yes	No	No	8	7
320	2x43	6x36	nts1_off	0	4.47	No	No	No	No	8	8
321	2x46	3x39	nts1_off	0	3.685	No	No	No	Yes	9	9
322	2x48	4x50	nts1_off	0	9.11	No	No	Yes	Yes	6	9
323	2x51	2x55	nts1_off	0	4.845	No	Yes	No	No	7	5
324	2x52	3x35	nts1_off	0	3.965	No	No	No	No	8	7
325	2x53	3x32	nts1_off	0	3.135	No	No	No	Yes	7	7
326	2x55	2x551	nts1_off	0	3.045	No	No	No	No	5	5
327	2x60	2x64	nts1_off	0	5.335	Yes	Yes	No	Yes	6	4
328	2x60	3x28	nts1_off	0	6.845	Yes	Yes	Yes	Yes	6	6
329	2x61	2x66	nts1_off	0	17.655	No	No	Yes	No	6	5
330	2x64	2x65	nts1_off	0	5.025	No	Yes	No	No	4	4
331	2x64	7x34	nts1_off	0	8.25	No	Yes	No	Yes	4	4
332	2x64	7x38	nts1_off	0	3.625	No	Yes	No	Yes	4	6
333	2x67	E1	nts1_off	0	7.805	No	No	No	No	5	4
334	E1x50	E2	nts1_off	0	4.555	Yes	Yes	Yes	Yes	8	3
335	3x25	E2	nts1_off	0	3.545	No	No	Yes	Yes	9	3
336	3x29	Lig	nts1_off	0	6.04	No	Yes	Yes	Yes	4	0
337	3x32	6x51	nts1_off	0	7.715	No	Yes	No	Yes	7	6
338	3x32	7x38	nts1_off	0	3.015	No	Yes	No	Yes	7	6
339	3x32	7x42	nts1_off	0	6.685	No	Yes	Yes	Yes	7	7
340	3x33	3x37	nts1_off	0	7.35	No	Yes	Yes	Yes	5	7
341	3x33	5x43	nts1_off	0	15.275	No	Yes	No	Yes	5	6
342	3x39	6x44	nts1_off	0	5.185	No	Yes	No	Yes	9	9
343	3x39	6x48	nts1_off	0	3.635	No	Yes	Yes	Yes	9	8
344	3x47	5x57	nts1_off	0	5.255	No	No	No	No	9	7
345	3x47	6x37	nts1_off	0	3.75	No	No	No	Yes	9	8
346	3x49	4x42	nts1_off	0	12.7	Yes	Yes	No	No	8	7
347	3x51	5x60	nts1_off	0	3.79	Yes	Yes	No	No	8	5
348	3x54	5x65	nts1_off	0	6.425	No	Yes	No	No	9	8
349	3x54	5x68	nts1_off	0	5.105	No	Yes	No	No	9	6
350	3x54	6x30	nts1_off	0	4.28	No	Yes	No	No	9	7
351	I2x50	I2x51	nts1_off	0	3.61	No	No	No	No	8	7
352	6x26	I2x54	nts1_off	0	5.57	No	Yes	No	No	4	4
353	I2x55	I2x56	nts1_off	0	5.16	No	No	No	No	4	4
354	4x38	4x40	nts1_off	0	3.26	No	No	No	No	8	4
355	4x65	Lig	nts1_off	0	5.005	No	No	Yes	Yes	6	0
356	5x36	E2x52	nts1_off	0	3.28	No	No	No	Yes	5	5
357	E2x52	Lig	nts1_off	0	3.15	No	Yes	Yes	Yes	5	0
358	5x36	6x58	nts1_off	0	9.745	No	No	No	No	5	4
359	5x36	Lig	nts1_off	0	3.56	No	No	Yes	Yes	5	0
360	5x40	6x58	nts1_off	0	7.535	No	No	No	No	6	4
361	5x44	6x55	nts1_off	0	3.88	No	No	Yes	Yes	6	6
362	5x45	5x49	nts1_off	0	3.215	No	No	No	No	5	6
363	5x47	6x48	nts1_off	0	3.505	Yes	Yes	Yes	Yes	8	8
364	5x49	5x53	nts1_off	0	3.935	No	No	No	No	6	6
365	5x52	5x56	nts1_off	0	4.28	No	No	No	No	3	5
366	5x53	5x57	nts1_off	0	2.98	No	No	No	No	6	7
367	5x63	5x66	nts1_off	0	3.235	No	No	No	No	4	5
368	5x64	5x68	nts1_off	0	4.34	No	No	No	No	5	6
369	5x65	5x69	nts1_off	0	2.98	No	No	No	No	8	6
370	6x26	6x30	nts1_off	0	8.505	No	Yes	No	No	4	7
371	6x28	6x31	nts1_off	0	3.505	No	No	No	No	5	5
372	6x28	6x32	nts1_off	0	3.505	No	No	No	Yes	5	8
373	6x31	6x35	nts1_off	0	3.035	No	No	No	No	5	7
374	6x37	6x41	nts1_off	0	2.98	No	Yes	No	No	8	8
375	6x47	6x48	nts1_off	0	3.92	No	No	Yes	Yes	9	8
376	6x48	6x51	nts1_off	0	5.305	Yes	Yes	No	Yes	8	6
377	6x49	6x53	nts1_off	0	2.98	No	No	No	No	7	5
378	6x51	6x52	nts1_off	0	9.255	No	Yes	No	Yes	6	7
379	6x51	7x41	nts1_off	0	6.535	No	Yes	Yes	Yes	6	7
380	6x53	7x33	nts1_off	0	4.585	No	No	No	No	5	4
381	6x55	Lig	nts1_off	0	6.3	Yes	Yes	Yes	Yes	6	0
382	6x56	6x60	nts1_off	0	5.275	No	No	No	No	6	5
383	6x61	7x30	nts1_off	0	3.025	No	No	Yes	Yes	3	4
384	6x61	Lig	nts1_off	0	5.085	No	No	Yes	Yes	3	0
385	7x32	7x36	nts1_off	0	13.48	No	No	No	No	1	6
386	7x43	7x48	nts1_off	0	3.07	No	No	No	No	5	6
387	7x45	7x49	nts1_off	0	2.98	No	Yes	Yes	Yes	9	9
388	7x53	7x54	nts1_off	0	8.725	Yes	Yes	No	No	9	7
389	1x31	NT	nts1_off	0	5.155	No	No	No	No	3	0
390	2x36	6x29	nts1_off	0	3.03	No	Yes	No	No	0	6
391	2x50	6x44	nts1_off	0	2.985	No	No	No	Yes	9	9
392	3x26	E2	nts1_off	0	3.34	No	No	Yes	Yes	7	3
393	I2x51	I2x52	nts1_off	0	4.345	No	No	No	No	7	4
394	5x64	5x67	nts1_off	0	3.925	No	No	No	No	5	4
395	6x32	6x35	nts1_off	0	4.25	No	Yes	No	No	8	7
396	6x44	7x45	nts1_off	0	4.625	No	Yes	No	Yes	9	9
397	6x44	7x49	nts1_off	0	5.435	No	Yes	Yes	Yes	9	9
398	E3	E3	nts1_off	0	7.66	No	Yes	No	Yes	3	3
399	7x26	E3	nts1_off	0	5.125	No	No	No	Yes	1	3
400	6x26	I2x50	nts1_off	0	2.88	No	Yes	No	No	4	8
401	1x38	1x42	nts1_off	0	2.85	No	No	No	No	4	7
402	3x53	6x26	nts1_off	0	2.77	No	No	No	Yes	8	4
403	1x54	2x51	nts1_off	0	2.765	No	No	No	Yes	8	7
404	2x56	3x32	nts1_off	0	2.765	No	No	No	Yes	7	7
405	5x66	5x70	nts1_off	0	2.74	No	No	No	No	5	4
406	2x33	6x25	nts1_off	0	2.465	No	Yes	No	No	0	0
407	1x29	1x30	nts1_off	0	2.42	No	No	No	No	2	2
408	6x43	7x49	nts1_off	0	2.345	No	No	Yes	Yes	7	9
409	5x34	E2	nts1_off	0	2.315	No	No	Yes	Yes	1	3
410	1x30	NT	nts1_off	0	2.3	No	No	No	No	2	0
411	2x39	2x43	nts1_off	0	2.235	No	No	No	No	8	8
412	2x39	3x46	nts1_off	0	2.235	No	No	No	No	8	9
413	3x48	3x52	nts1_off	0	2.235	No	No	Yes	No	7	4
414	5x42	5x46	nts1_off	0	2.12	No	No	No	No	5	5
415	3x21	E1x50	nts1_off	0	2.11	No	No	Yes	Yes	8	8
416	6x24	6x25	nts1_off	0	2.03	No	No	No	No	0	0
417	3x43	6x44	nts1_off	0	1.965	No	No	No	Yes	8	9
418	2x44	2x47	nts1_off	0	1.95	No	No	No	No	6	9
419	3x44	5x50	nts1_off	0	1.77	No	No	No	No	8	9
420	3x26	3x27	nts1_off	0	1.74	No	No	No	No	7	5
421	1x51	1x54	nts1_off	0	1.71	No	No	No	No	4	8
422	5x62	6x34	nts1_off	0	1.7	No	No	No	No	6	7
423	7x31	Lig	nts1_off	0	1.665	No	No	Yes	Yes	4	0
424	5x55	6x41	nts1_off	0	1.62	No	No	No	No	5	8
425	1x44	1x45	nts1_off	0	1.6	No	No	No	No	5	6
426	1x48	1x52	nts1_off	0	1.6	No	No	Yes	No	5	6
427	5x56	5x60	nts1_off	0	1.54	No	No	No	No	5	5
428	6x42	6x46	nts1_off	0	1.54	No	No	No	No	5	6
429	7x24	7x28	nts1_off	0	1.445	No	No	No	No	4	1
430	1x34	1x38	nts1_off	0	1.425	No	No	No	No	5	4
431	1x43	1x44	nts1_off	0	1.31	No	No	No	No	7	5
432	1x55	1x59	nts1_off	0	1.07	No	No	No	No	4	5
433	3x53	I2x53	nts1_off	0	0.895	No	No	No	No	8	6
434	7x23	7x25	nts1_off	0	0.84	No	No	No	No	4	2
435	1x29	1x33	nts1_off	0	0.77	No	No	No	No	2	6
436	1x31	7x35	nts1_off	0	0.765	No	No	No	No	3	3
437	4x40	4x43	nts1_off	0	0.765	No	No	No	No	4	3
438	4x55	4x59	nts1_off	0	0.715	No	No	No	Yes	4	5
439	1x58	1x59	nts1_off	0	0.69	No	No	No	No	4	5
440	6x39	7x53	nts1_off	0	0.665	No	No	Yes	Yes	7	9
441	5x63	5x67	nts1_off	0	0.655	No	No	No	No	4	4
442	1x56	1x59	nts1_off	0	0.645	Yes	No	No	No	7	5
443	7x28	7x31	nts1_off	0	0.63	No	No	No	No	1	4

Orange: nodes, hubs and links specific of nts1_off_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of nts1_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	nts1_off_allo Avg Int. Strength	nts1_off Avg Int. Strength	nts1_off_allo Num Of Links	nts1_off Num Of Links	ConSurf
1	1x50	nts1_off_allo	6.8625	8.58167	4	3	9
2	1x52	nts1_off_allo	5.7225	1.595	4	2	6
3	1x56	nts1_off_allo	4.318	1.1175	5	2	7
4	2x41	nts1_off_allo	6.12	8.745	4	1	5
5	2x49	nts1_off_allo	4.262	4.47	5	2	8
6	2x63	nts1_off_allo	8.865	9.48833	4	3	5
7	2x66	nts1_off_allo	8.5725	14.8925	4	2	5
8	3x30	nts1_off_allo	4.1575	5.27167	4	3	6
9	3x50	nts1_off_allo	6.922	3.28667	5	3	9
10	3x52	nts1_off_allo	3.9175	2.1775	4	2	4
11	3x55	nts1_off_allo	4.3	6.915	4	2	7
12	3x56	nts1_off_allo	3.8625	4.3875	4	2	6
13	4x49	nts1_off_allo	3.45	5.315	4	3	7
14	4x64	nts1_off_allo	4.565	3.8475	4	2	5
15	5x58	nts1_off_allo	6.6075	11.2175	4	2	9
16	6x57	nts1_off_allo	5.41	7.7025	4	2	4
17	6x59	nts1_off_allo	5.35	7.88167	4	3	3
18	7x50	nts1_off_allo	4.335	7.1225	4	2	9
19	8x50	nts1_off_allo	7.42	0	5	0	8
20	8x54	nts1_off_allo	9.61	0	5	0	7
21	8x57	nts1_off_allo	3.9125	0	4	0	5
22	1x39	Shared	5.19714	4.79571	7	7	7
23	2x57	Shared	7.745	6.00875	4	4	8
24	2x60	Shared	5.904	7.25583	5	6	6
25	2x62	Shared	5.8275	6.51625	4	4	5
26	E1x50	Shared	9.2925	7.9475	4	6	8
27	E1x52	Shared	6.666	7.194	5	5	7
28	3x28	Shared	10.27	10.0013	4	4	6
29	3x37	Shared	8.5725	8.509	4	5	7
30	3x49	Shared	7.9675	10.8538	4	4	8
31	3x51	Shared	6.686	7.31875	5	4	8
32	4x50	Shared	4.015	7.0025	4	4	9
33	E2	Shared	20.0911	9.89167	9	9	3
34	5x461	Shared	4.6625	5.09625	4	4	6
35	5x47	Shared	9.0375	8.41125	4	4	8
36	6x48	Shared	7.6925	5.96938	4	8	8
37	6x54	Shared	8.34	10.515	6	5	5
38	6x55	Shared	7.025	6.284	4	5	6
39	7x30	Shared	8.1975	6.334	4	5	4
40	7x41	Shared	8.83	8.432	4	5	7
41	7x42	Shared	11.53	8.184	4	5	7
42	7x49	Shared	4.212	3.49417	5	6	9
43	7x53	Shared	9.3	5.2725	4	4	9
44	Lig	Shared	10.865	7.92357	8	14	0
45	2x33	nts1_off	0	2.90375	0	4	0
46	2x36	nts1_off	0	6.07	0	4	0
47	2x38	nts1_off	4.23	7.611	1	5	7
48	2x42	nts1_off	9.915	8.66	2	5	8
49	2x51	nts1_off	3.535	3.6825	2	4	7
50	2x64	nts1_off	7.22	5.55875	1	4	4
51	3x29	nts1_off	9.09333	8.75375	3	4	4
52	3x32	nts1_off	11.71	6.28687	3	8	7
53	3x33	nts1_off	4.93	8.6625	2	4	5
54	3x39	nts1_off	6.775	4.12625	2	4	9
55	3x54	nts1_off	4.57333	4.56125	3	4	9
56	4x59	nts1_off	3.04333	2.055	3	4	5
57	E2x52	nts1_off	7.69	4.3875	2	4	5
58	5x43	nts1_off	7.59333	8.59625	3	4	6
59	6x26	nts1_off	4.59	4.93125	2	4	4
60	6x32	nts1_off	4.82	5.73625	1	4	8
61	6x37	nts1_off	4	5.066	3	5	8
62	6x44	nts1_off	6.36333	4.86917	3	6	9
63	6x51	nts1_off	6.69	7.88833	2	6	6
64	6x52	nts1_off	8.95667	11.3263	3	4	7
65	E3	nts1_off	8.65667	6.19625	3	4	3
66	7x34	nts1_off	10.3833	11.6563	3	4	4
67	7x38	nts1_off	5.26	5.791	3	5	6
68	7x45	nts1_off	6.66	4.18	2	4	9

Orange: nodes, hubs and links specific of nts1_off_allo network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of nts1_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	nts1_off_allo Recurrence	nts1_off Recurrence	nts1_off_allo Hub1?	nts1_off Hub1?	nts1_off_allo Hub2?	nts1_off Hub2?	ConSurf1	ConSurf2
1	2x65	2x66	nts1_off_allo	11.673	0	No	No	Yes	No	4	5
2	2x60	2x65	nts1_off_allo	12.8706	0	Yes	Yes	No	No	6	4
3	2x60	7x42	nts1_off_allo	31.876	3.5801	Yes	Yes	Yes	Yes	6	7
4	2x60	3x32	nts1_off_allo	36.8492	2.7137	Yes	Yes	No	Yes	6	7
5	2x53	7x41	nts1_off_allo	100	2.36604	No	No	Yes	Yes	7	7
6	2x53	7x46	nts1_off_allo	49.4216	0	No	No	No	No	7	9
7	2x50	7x46	nts1_off_allo	47.7383	0.998841	No	No	No	No	9	9
8	1x50	7x50	nts1_off_allo	39.0857	7.96728	Yes	No	Yes	No	9	9
9	7x49	7x50	nts1_off_allo	37.3422	0	Yes	Yes	Yes	No	9	9
10	7x53	8x50	nts1_off_allo	11.8197	0	Yes	Yes	Yes	No	9	8
11	2x53	3x35	nts1_off_allo	52.9904	2.27498	No	No	No	No	7	7
12	2x49	3x35	nts1_off_allo	51.6726	0	Yes	No	No	No	8	7
13	3x50	6x37	nts1_off_allo	31.0968	3.26969	Yes	No	No	Yes	9	8
14	2x60	7x38	nts1_off_allo	61.3809	2.02941	Yes	Yes	No	Yes	6	6
15	3x28	3x29	nts1_off_allo	22.3769	8.2501	Yes	Yes	No	Yes	6	4
16	6x54	7x38	nts1_off_allo	35.6444	2.88064	Yes	Yes	No	Yes	5	6
17	6x40	7x49	nts1_off_allo	27.1217	0.829148	No	No	Yes	Yes	8	9
18	3x43	6x40	nts1_off_allo	26.4916	0	No	No	No	No	8	8
19	3x43	6x41	nts1_off_allo	25.8615	0	No	No	No	No	8	8
20	5x54	6x41	nts1_off_allo	25.2315	0	No	No	No	No	8	8
21	3x47	5x54	nts1_off_allo	23.3485	0.911925	No	No	No	No	9	8
22	5x58	6x37	nts1_off_allo	20.7657	3.63529	Yes	No	No	Yes	9	8
23	5x58	5x61	nts1_off_allo	32.1862	0	Yes	No	No	No	9	9
24	3x51	5x61	nts1_off_allo	21.2491	0	Yes	Yes	No	No	8	9
25	3x47	5x58	nts1_off_allo	22.7569	0	No	No	Yes	No	9	9
26	3x54	3x55	nts1_off_allo	12.7047	0	No	Yes	Yes	No	9	7
27	5x40	6x55	nts1_off_allo	10.4538	1.4417	No	No	Yes	Yes	6	6
28	5x40	6x59	nts1_off_allo	18.0819	0	No	No	Yes	No	6	3
29	5x40	Lig	nts1_off_allo	13.758	0.0772584	No	No	Yes	Yes	6	0
30	7x34	7x38	nts1_off_allo	24.8299	1.59208	No	Yes	No	Yes	4	6
31	7x34	Lig	nts1_off_allo	23.8102	3.14966	No	Yes	Yes	Yes	4	0
32	3x55	5x64	nts1_off_allo	17.4711	0	Yes	No	No	No	7	5
33	3x50	3x53	nts1_off_allo	18.3681	0	Yes	No	No	No	9	8
34	3x53	6x30	nts1_off_allo	17.3821	0	No	No	No	No	8	7
35	5x72	6x30	nts1_off_allo	16.5043	0	No	No	No	No	5	7
36	7x27	Lig	nts1_off_allo	11.5023	1.5093	No	No	Yes	Yes	2	0
37	7x30	Lig	nts1_off_allo	13.8206	9.20617	Yes	Yes	Yes	Yes	4	0
38	3x29	4x61	nts1_off_allo	13.9312	9.17168	No	Yes	No	No	4	5
39	3x32	7x41	Shared	55.4097	14.0403	No	Yes	Yes	Yes	7	7
40	6x48	7x41	Shared	24.2527	26.4072	Yes	Yes	Yes	Yes	8	7
41	7x41	7x42	Shared	37.2051	11.6853	Yes	Yes	Yes	Yes	7	7
42	1x50	2x50	Shared	47.2284	19.4636	Yes	No	No	No	9	9
43	7x49	7x53	Shared	15.2851	28.3621	Yes	Yes	Yes	Yes	9	9
44	2x49	4x50	Shared	49.8617	37.8953	Yes	No	Yes	Yes	8	9
45	2x45	4x50	Shared	49.5924	37.1172	No	No	Yes	Yes	9	9
46	2x45	3x42	Shared	46.9831	36.5612	No	No	No	No	9	8
47	3x42	4x49	Shared	48.4741	37.2399	No	No	Yes	No	8	7
48	3x45	4x49	Shared	46.4348	36.8233	No	No	Yes	No	7	7
49	2x42	3x45	Shared	45.9803	36.437	No	Yes	No	No	8	7
50	2x42	3x46	Shared	45.3551	10.9293	No	Yes	No	No	8	9
51	3x46	6x37	Shared	44.7082	23.1375	No	No	No	Yes	9	8
52	3x28	3x32	Shared	31.1618	23.2865	Yes	Yes	No	Yes	6	7
53	3x36	6x48	Shared	10.6823	20.6694	No	No	Yes	Yes	7	8
54	3x36	5x461	Shared	10.1724	19.9685	No	No	Yes	Yes	7	6
55	6x54	Lig	Shared	25.3277	23.4631	Yes	Yes	Yes	Yes	5	0
56	6x44	6x48	Shared	11.4085	20.519	No	Yes	Yes	Yes	9	8
57	6x44	7x49	nts1_off	0	20.0679	No	Yes	Yes	Yes	9	9
58	6x48	7x45	nts1_off	3.9319	14.3977	Yes	Yes	No	Yes	8	9
59	7x45	7x49	nts1_off	0	14.457	No	Yes	Yes	Yes	9	9
60	1x43	2x57	nts1_off	3.56155	10.6023	No	No	Yes	Yes	7	8
61	1x50	2x51	nts1_off	8.04415	11.3308	Yes	No	No	Yes	9	7
62	2x50	6x44	nts1_off	0	21.3068	No	No	No	Yes	9	9
63	3x39	6x48	nts1_off	0	100	No	Yes	Yes	Yes	9	8
64	2x46	3x39	nts1_off	0	73.7666	No	No	No	Yes	9	9
65	2x46	3x42	nts1_off	6.1732	73.7432	No	No	No	No	9	8
66	2x45	4x46	nts1_off	5.71147	73.0065	No	No	No	No	9	7
67	2x42	4x46	nts1_off	0	72.4408	No	Yes	No	No	8	7
68	2x42	3x49	nts1_off	0	60.1209	No	Yes	Yes	Yes	8	8
69	2x38	3x49	nts1_off	0.954717	55.6192	No	Yes	Yes	Yes	7	8
70	2x35	2x38	nts1_off	0	97.6381	No	No	No	Yes	0	7
71	2x35	6x29	nts1_off	0	48.4493	No	No	No	No	0	6
72	2x36	6x29	nts1_off	0	22.0697	No	Yes	No	No	0	6
73	2x49	3x39	nts1_off	0.791189	38.0953	Yes	No	No	Yes	8	9
74	2x42	4x42	nts1_off	0	56.9201	No	Yes	No	No	8	7
75	2x38	4x42	nts1_off	0	55.8799	No	Yes	No	No	7	7
76	2x34	2x38	nts1_off	0	12.2289	No	No	No	Yes	0	7
77	2x33	6x29	nts1_off	0	24.4868	No	Yes	No	No	0	6
78	2x33	6x32	nts1_off	0	17.1693	No	Yes	No	Yes	0	8
79	2x36	6x32	nts1_off	0	17.1983	No	Yes	No	Yes	0	8
80	2x35	6x30	nts1_off	0	47.9761	No	No	No	No	0	7
81	2x43	7x53	nts1_off	0.988385	26.8142	No	No	Yes	Yes	8	9
82	2x39	2x43	nts1_off	0	26.0789	No	No	No	No	8	8
83	2x39	3x46	nts1_off	0	25.7243	No	No	No	No	8	9
84	2x59	3x28	nts1_off	9.89587	18.6952	No	No	Yes	Yes	6	6
85	2x59	E1x52	nts1_off	9.09266	17.4356	No	No	Yes	Yes	6	7
86	E2x52	Lig	nts1_off	0	12.2579	No	Yes	Yes	Yes	5	0
87	E2x51	E2x52	nts1_off	0.783974	11.0866	No	No	No	Yes	4	5
88	3x33	4x57	nts1_off	7.22651	19.1573	No	Yes	No	No	5	7
89	3x30	4x57	nts1_off	5.65375	14.9192	Yes	No	No	No	6	7
90	3x30	4x62	nts1_off	3.25854	10.6699	Yes	No	No	No	6	5
91	3x32	6x51	nts1_off	0	17.1845	No	Yes	No	Yes	7	6
92	3x37	5x461	nts1_off	1.90943	11.5612	Yes	Yes	Yes	Yes	7	6
93	6x51	6x55	nts1_off	0.0889787	38.0705	No	Yes	Yes	Yes	6	6
94	5x43	6x55	nts1_off	6.84414	10.5899	No	Yes	Yes	Yes	6	6
95	6x55	Lig	nts1_off	0	23.6107	Yes	Yes	Yes	Yes	6	0
96	3x47	6x37	nts1_off	0	14.2763	No	No	No	Yes	9	8
97	3x47	5x57	nts1_off	0	12.5338	No	No	No	No	9	7
98	3x54	6x30	nts1_off	0	24.6537	No	Yes	No	No	9	7
99	3x54	5x68	nts1_off	0	14.8322	No	Yes	No	No	9	6
100	6x26	6x30	nts1_off	0	21.6517	No	Yes	No	No	4	7
101	6x26	I2x50	nts1_off	0	12.3462	No	Yes	No	No	4	8
102	5x44	6x56	nts1_off	1.45011	12.7794	No	No	No	No	6	6
103	6x56	6x60	nts1_off	0	10.6561	No	No	No	No	6	5
104	5x47	6x48	nts1_off	0	11.8964	Yes	Yes	Yes	Yes	8	8
105	5x64	5x68	nts1_off	0	12.3669	No	No	No	No	5	6
106	6x28	6x32	nts1_off	0	14.7343	No	No	No	Yes	5	8
107	6x32	6x35	nts1_off	0	14.7343	No	Yes	No	No	8	7
108	7x31	Lig	nts1_off	0	16.1636	No	No	Yes	Yes	4	0
109	7x31	7x35	nts1_off	2.35673	11.4839	No	No	No	No	4	3
110	3x33	5x43	nts1_off	0	17.0093	No	Yes	No	Yes	5	6
111	6x51	6x54	nts1_off	1.06774	25.6263	No	Yes	Yes	Yes	6	5
112	2x57	7x42	nts1_off	4.26617	10.4934	Yes	Yes	Yes	Yes	8	7
113	6x48	6x51	nts1_off	0	78.4021	Yes	Yes	No	Yes	8	6
114	3x39	6x44	nts1_off	0	11.7088	No	Yes	No	Yes	9	9

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
2x64	7x34	nts1_off	8.25	0	1	0	2	1
2x64	7x38	nts1_off	3.625	0	1	0	2	2
3x28	3x29	Shared	13.405	12.91	1	0	2	1
3x29	4x61	Shared	2.995	3.59	1	0	1	2
3x29	4x65	Shared	12.575	10.78	1	0	1	1
3x29	Lig	nts1_off	6.04	0	1	0	1	0
4x61	4x64	Shared	4.52	7.53	0	0	2	2
4x65	E2x52	Shared	5.87	8.39	1	0	1	1
4x65	Lig	nts1_off	5.005	0	1	0	1	0
E2	E2	Shared	22.57	69.89	1	4	2	2
E2	E2x51	Shared	13.18	7.42	1	4	2	2
E2x51	E2x52	Shared	5.25	6.99	1	4	2	1
5x36	E2x52	nts1_off	3.28	0	1	0	1	1
E2x52	Lig	nts1_off	3.15	0	1	0	1	0
5x36	6x58	nts1_off	9.745	0	1	0	1	1
5x36	Lig	nts1_off	3.56	0	1	0	1	0
5x40	6x55	Shared	5.01	7.52	1	0	1	1
5x40	6x58	nts1_off	7.535	0	1	0	1	1
5x40	Lig	Shared	4.145	4.65	1	0	1	0
5x43	6x55	Shared	5.425	6.03	1	1	2	1
5x44	6x55	nts1_off	3.88	0	0	0	2	1
6x51	6x54	Shared	7.715	3.09	1	1	2	1
6x51	6x55	Shared	10.805	10.29	1	1	2	1
6x53	7x33	nts1_off	4.585	0	0	0	2	2
6x54	7x34	Shared	15.95	12.35	1	1	1	1
6x54	7x37	Shared	9.225	11.64	1	1	1	2
6x54	7x38	Shared	9.04	6.03	1	1	1	2
6x54	Lig	Shared	10.645	12.67	1	1	1	0
6x55	Lig	nts1_off	6.3	0	1	1	1	0
6x57	7x33	Shared	4.975	7.46	0	0	1	2
6x57	Lig	Shared	10.43	8.29	0	0	1	0
6x58	Lig	Shared	20.055	30.17	1	0	1	0
6x61	7x30	nts1_off	3.025	0	1	0	1	1
6x61	Lig	nts1_off	5.085	0	1	0	1	0
7x29	7x30	Shared	4.125	6.19	0	0	2	1
7x30	Lig	Shared	14.32	8.41	1	1	1	0
7x31	7x35	Shared	7.88	6.57	0	0	1	2
7x34	Lig	Shared	17.775	12.99	1	1	1	0
E3	E3	nts1_off	7.66	0	1	1	1	1
7x26	E3	nts1_off	5.125	0	1	0	2	1
7x30	E3	Shared	4.34	13.5	1	1	1	1
7x26	7x30	Shared	5.86	4.69	1	0	2	1
7x34	7x38	Shared	4.65	5.81	1	1	1	2
7x27	Lig	Shared	2.755	3.06	0	1	1	0
7x31	Lig	nts1_off	1.665	0	0	0	1	0
7x28	7x31	nts1_off	0.63	0	0	0	2	1
2x64	3x28	nts1_off_allo	0	7.22	1	0	2	2
4x64	4x65	nts1_off_allo	0	4.52	0	4	2	1
4x64	E2	nts1_off_allo	0	3.04	0	4	2	2
5x36	E2	nts1_off_allo	0	3.07	1	0	1	2
5x40	6x59	nts1_off_allo	0	3.27	1	0	1	2
6x54	6x55	nts1_off_allo	0	4.26	1	1	1	1
6x57	6x61	nts1_off_allo	0	4.37	0	0	1	1
7x27	E3	nts1_off_allo	0	5.79	0	1	1	1
E3	Lig	nts1_off_allo	0	6.68	1	1	1	0
7x28	7x32	nts1_off_allo	0	3.45	0	0	2	2
7x31	7x32	nts1_off_allo	0	3.27	0	0	1	2
7x33	7x37	nts1_off_allo	0	5.19	0	0	2	2
7x27	7x28	nts1_off_allo	0	2.3	0	1	1	2
6x53	6x57	nts1_off_allo	0	1.52	0	0	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	nts1_off_allo	7UL2-NTS₁-SR48692-Na
	nts1_off	6Z4Q-NTS₁-SR142948A 6Z4S-NTS₁-SR48692

Network Difference
Value	nts1_off_allo	nts1_off
I_min	2.96	2.92
Number of Linked Nodes	256	252
Number of Specific Nodes	25 (9.77%)	21 (8.33%)
Number of Shared Nodes	231 (90.23%)	231 (91.67%)
Number of Links	296	310
Number of Specific Links	133 (44.93%)	147 (47.42%)
Number of Shared Links	163 (55.07%)	163 (52.58%)
Number of Hubs	44	47
Number of Specific Hubs	21 (47.73%)	24 (51.06%)
Number of Shared Hubs	23 (52.27%)	23 (48.94%)
Average % Shared Neighbours (Jaccard)	37.75
Average % Shared Neighbours (Otsuka)	46.25
Average % Shared Neighbours (Overlap Coefficient)	55.11
Average % Shared Cliques (k3-6)	79.39
Graphlets Similarity	0.621815

Paths Difference
Value	nts1_off_allo	nts1_off
Number Of Nodes in MetaPath	55	69
Specific Nodes in MetaPath	27 (49.09%)	41 (59.42%)
Shared Nodes in MetaPath	231 (90.23%)	231 (90.23%)
Number Of Links MetaPath	56	76
Specific Links in MetaPath	38 (67.86%)	58 (76.32%)
Shared Links in MetaPath	163 (55.07%)	163 (55.07%)
Number of Shortest Paths	66264	138376
Length Of Smallest Path	3	3
Average Path Length	15.8683	15.6186
Length of Longest Path	32	28
Minimum Path Strength	1.295	0.6675
Average Path Strength	6.06071	6.0746
Maximum Path Strength	21.58	16.2825
Minimum Path Correlation	0.7	0.7
Average Path Correlation	0.933206	0.91155
Maximum Path Correlation	0.99	0.99
Minimum % Of Corr. Nodes	3.84615	5
Average % Of Corr. Nodes	47.5419	34.4203
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	39.9957	48.9925
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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