psnGPCR

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Orange: nodes, hubs and links specific of nucleotide_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of nucleotide_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	nucleotide_off Int. Strength	nucleotide_on Int. Strength	nucleotide_off Hub1?	nucleotide_on Hub1?	nucleotide_off Hub2?	nucleotide_on Hub2?	ConSurf1	ConSurf2
1	1x36	2x65	nucleotide_off	100	0	No	No	No	No	5	4
2	1x39	2x60	nucleotide_off	100	0	Yes	Yes	No	No	6	7
3	1x39	7x39	nucleotide_off	100	0	Yes	Yes	No	Yes	6	5
4	1x40	2x61	nucleotide_off	100	0	No	No	No	No	4	6
5	1x49	7x50	nucleotide_off	100	0	No	No	No	No	8	9
6	1x53	7x53	nucleotide_off	100	0	No	No	Yes	Yes	9	9
7	1x55	8x57	nucleotide_off	100	0	Yes	No	No	No	4	7
8	2x38	3x49	nucleotide_off	100	0	No	No	Yes	No	6	9
9	2x39	2x43	nucleotide_off	100	0	No	No	No	No	8	8
10	2x39	3x50	nucleotide_off	100	0	No	No	Yes	No	8	9
11	2x42	3x46	nucleotide_off	100	0	Yes	Yes	No	No	8	9
12	2x43	7x53	nucleotide_off	100	0	No	No	Yes	Yes	8	9
13	2x45	4x50	nucleotide_off	100	0	No	No	Yes	No	9	9
14	2x53	3x35	nucleotide_off	100	0	No	No	No	No	8	7
15	3x22	3x26	nucleotide_off	100	0	No	No	No	No	3	5
16	3x23	E2	nucleotide_off	100	0	No	No	Yes	Yes	1	3
17	3x29	E2x52	nucleotide_off	100	0	No	No	No	Yes	4	4
18	3x32	3x33	nucleotide_off	100	0	No	No	No	No	6	4
19	3x33	Lig	nucleotide_off	100	0	No	No	Yes	Yes	4	0
20	3x36	6x48	nucleotide_off	100	0	No	No	Yes	Yes	6	8
21	3x37	5x43	nucleotide_off	100	0	Yes	Yes	No	No	6	5
22	3x44	5x54	nucleotide_off	100	0	No	No	No	No	7	8
23	3x47	5x54	nucleotide_off	100	0	No	No	No	No	9	8
24	3x49	3x50	nucleotide_off	100	0	Yes	No	Yes	No	9	9
25	3x49	I2x57	nucleotide_off	100	0	Yes	No	No	No	9	7
26	3x50	3x53	nucleotide_off	100	0	Yes	No	No	No	9	8
27	3x50	6x33	nucleotide_off	100	0	Yes	No	No	No	9	7
28	3x51	5x61	nucleotide_off	100	0	Yes	No	No	No	7	9
29	5x47	5x51	nucleotide_off	100	0	No	No	No	No	5	6
30	5x51	6x45	nucleotide_off	100	0	No	No	No	No	6	6
31	5x58	6x38	nucleotide_off	100	0	Yes	Yes	No	No	9	6
32	5x65	6x31	nucleotide_off	100	0	No	No	No	No	8	5
33	5x68	6x27	nucleotide_off	100	0	No	No	No	No	7	1
34	6x40	7x52	nucleotide_off	100	0	No	No	No	No	8	8
35	6x44	7x45	nucleotide_off	100	0	Yes	Yes	Yes	No	9	9
36	6x51	7x38	nucleotide_off	100	0	No	No	No	No	6	5
37	6x58	Lig	nucleotide_off	100	0	Yes	No	Yes	Yes	4	0
38	6x59	6x60	nucleotide_off	100	0	Yes	No	No	No	4	4
39	7x34	7x38	nucleotide_off	100	0	No	No	No	No	4	5
40	7x49	7x53	nucleotide_off	100	0	Yes	Yes	Yes	Yes	9	9
41	7x53	8x50	nucleotide_off	100	0	Yes	Yes	Yes	Yes	9	9
42	1x31	7x35	nucleotide_off	100	0	No	No	No	Yes	4	3
43	1x57	7x53	nucleotide_off	100	0	No	No	Yes	Yes	8	9
44	I2x51	I2x52	nucleotide_off	100	0	No	No	No	No	6	5
45	E1x50	E2x50	nucleotide_off	100	0	No	No	No	No	3	9
46	E3	NT	nucleotide_off	100	0	No	Yes	Yes	No	3	0
47	7x24	NT	nucleotide_off	100	0	No	No	Yes	No	0	0
48	Lig	NT	nucleotide_off	100	0	Yes	Yes	Yes	No	0	0
49	7x28	NT	nucleotide_off	100	0	No	No	Yes	No	0	0
50	7x31	NT	nucleotide_off	100	0	No	No	Yes	No	3	0
51	1x32	E1	nucleotide_off	100	0	No	Yes	No	No	4	0
52	I1	I1	nucleotide_off	100	0	No	No	No	No	0	0
53	2x44	I1	nucleotide_off	100	0	Yes	No	No	No	5	0
54	2x60	2x64	nucleotide_off	100	0	No	No	Yes	No	7	3
55	3x36	3x37	nucleotide_off	100	0	No	No	Yes	Yes	6	6
56	3x37	6x52	nucleotide_off	100	0	Yes	Yes	No	No	6	7
57	3x42	4x49	nucleotide_off	100	0	No	No	No	No	8	7
58	3x42	4x50	nucleotide_off	100	0	No	No	Yes	No	8	9
59	4x63	5x36	nucleotide_off	100	0	No	No	No	No	5	5
60	5x47	5x48	nucleotide_off	100	0	No	No	No	No	5	5
61	5x58	6x42	nucleotide_off	100	0	Yes	Yes	No	No	9	5
62	6x58	7x34	nucleotide_off	100	0	Yes	No	No	No	4	4
63	6x62	Lig	nucleotide_off	100	0	No	No	Yes	Yes	0	0
64	7x23	E3	nucleotide_off	100	0	No	No	No	Yes	0	3
65	8x51	8x53	nucleotide_off	100	0	No	No	No	Yes	8	6
66	4x59	5x35	nucleotide_off	100	0	No	No	No	No	6	0
67	5x44	6x55	nucleotide_off	100	0	Yes	Yes	Yes	No	5	5
68	6x46	6x49	nucleotide_off	100	0	No	No	No	No	6	7
69	5x33	6x62	nucleotide_off	50	0	No	No	No	No	0	0
70	3x55	3x56	nucleotide_off	65	0	No	No	No	No	7	6
71	1x43	2x58	nucleotide_off	50	0	No	No	No	No	5	8
72	5x51	5x55	nucleotide_off	50	0	No	No	No	No	6	5
73	1x58	1x59	nucleotide_off	55	0	No	No	No	No	3	5
74	3x50	6x30	nucleotide_off	75	0	Yes	No	Yes	Yes	9	6
75	2x54	2x57	nucleotide_off	75	0	No	No	Yes	Yes	7	6
76	6x58	7x30	nucleotide_off	50	0	Yes	No	No	No	4	4
77	6x54	7x37	nucleotide_off	50	0	No	No	No	No	4	5
78	1x56	8x53	nucleotide_off	62.5	0	No	No	No	Yes	8	6
79	E1x49	E2	nucleotide_off	50	0	No	No	Yes	Yes	0	3
80	8x49	8x52	nucleotide_off	52.5	0	No	No	No	No	6	4
81	2x63	2x64	nucleotide_off	50	0	No	No	Yes	No	3	3
82	1x43	1x44	nucleotide_off	50	0	No	No	No	No	5	5
83	2x47	7x53	nucleotide_off	50	0	No	No	Yes	Yes	9	9
84	1x30	1x35	nucleotide_off	50	0	No	No	Yes	Yes	5	5
85	5x63	5x67	nucleotide_off	50	0	No	No	No	No	4	4
86	6x34	6x37	nucleotide_off	50	0	No	No	No	No	7	8
87	3x54	6x30	nucleotide_off	50	0	No	No	Yes	Yes	9	6
88	1x60	I1x49	nucleotide_off	50	0	No	No	No	No	6	6
89	5x65	6x32	nucleotide_off	50	0	No	No	No	No	8	7
90	1x60	8x49	nucleotide_off	50	0	No	No	No	No	6	6
91	7x30	7x32	nucleotide_off	50	0	No	No	No	No	4	1
92	3x52	I2x57	nucleotide_off	50	0	No	No	No	No	5	7
93	6x40	7x49	nucleotide_off	50	0	No	No	Yes	Yes	8	9
94	1x42	7x47	nucleotide_off	50	0	No	No	No	No	7	6
95	3x27	3x31	nucleotide_off	25	0	No	No	No	No	4	4
96	4x54	4x58	nucleotide_off	52.5	0	No	No	No	No	3	4
97	5x38	E2	nucleotide_off	50	0	No	No	Yes	Yes	3	3
98	1x47	1x51	nucleotide_off	25	0	No	No	No	No	6	5
99	8x50	8x54	nucleotide_off	50	0	Yes	Yes	Yes	No	9	7
100	2x56	3x28	nucleotide_off	50	0	No	No	No	No	6	6
101	6x60	6x64	nucleotide_off	50	0	No	No	No	No	4	0
102	6x54	7x33	nucleotide_off	30	0	No	No	No	No	4	4
103	7x54	8x54	nucleotide_off	25	0	No	No	Yes	No	7	7
104	8x58	8x63	nucleotide_off	50	0	No	No	No	No	5	4
105	3x34	4x53	nucleotide_off	25	0	No	No	No	No	5	8
106	2x49	4x50	nucleotide_off	0	0	No	No	Yes	No	8	9
107	1x29	NT	nucleotide_off	50	0	No	No	Yes	No	6	0
108	1x54	2x51	nucleotide_off	12.5	0	No	No	No	No	7	7
109	7x27	NT	nucleotide_off	50	0	No	No	Yes	No	0	0
110	6x26	6x30	nucleotide_off	50	0	No	No	Yes	Yes	3	6
111	5x69	6x27	nucleotide_off	50	0	No	No	No	No	4	1
112	8x55	8x59	nucleotide_off	50	0	No	No	No	No	5	4
113	5x41	6x56	nucleotide_off	50	0	No	No	No	No	4	5
114	3x39	6x44	nucleotide_off	50	0	No	No	Yes	Yes	9	9
115	5x60	5x63	nucleotide_off	37.5	0	No	No	No	No	4	4
116	7x54	7x55	nucleotide_off	50	0	No	No	No	No	7	6
117	6x32	7x56	nucleotide_off	50	0	No	No	No	No	7	7
118	3x30	4x60	nucleotide_off	50	0	No	No	No	No	6	4
119	3x24	E1x52	nucleotide_off	50	0	No	No	No	No	5	7
120	6x49	6x53	nucleotide_off	32.5	0	No	No	No	No	7	6
121	1x58	2x44	nucleotide_off	37.5	0	No	No	Yes	No	3	5
122	6x36	7x55	nucleotide_off	50	0	No	No	No	No	8	6
123	1x30	7x36	nucleotide_off	50	0	No	No	No	No	5	3
124	3x52	I2x56	nucleotide_off	32.5	0	No	No	No	No	5	4
125	7x43	7x48	nucleotide_off	25	0	No	No	No	No	5	6
126	5x62	5x66	nucleotide_off	30	0	No	No	No	No	6	5
127	4x62	4x63	nucleotide_off	50	0	No	No	No	No	4	5
128	5x34	6x63	nucleotide_off	50	0	No	No	No	No	0	0
129	2x62	2x66	nucleotide_off	50	0	No	No	No	No	4	3
130	5x68	6x32	nucleotide_off	50	0	No	No	No	No	7	7
131	7x23	7x26	nucleotide_off	25	0	No	No	No	No	0	0
132	5x58	6x39	nucleotide_off	25	0	Yes	Yes	No	No	9	6
133	2x38	4x38	nucleotide_off	25	0	No	No	No	No	6	8
134	3x41	4x52	nucleotide_off	50	0	No	No	No	No	4	4
135	6x35	6x39	nucleotide_off	25	0	No	No	No	No	7	6
136	1x55	8x61	nucleotide_off	50	0	Yes	No	No	No	4	6
137	2x41	4x43	nucleotide_off	20	0	Yes	No	No	No	4	1
138	3x48	3x52	nucleotide_off	37.5	0	No	No	No	No	6	5
139	3x55	5x64	nucleotide_off	2.5	0	No	No	No	No	7	5
140	2x44	2x48	nucleotide_off	25	0	Yes	No	No	No	5	6
141	5x62	6x35	nucleotide_off	50	0	No	No	No	No	6	7
142	2x51	2x55	nucleotide_off	25	0	No	No	No	No	7	4
143	1x32	2x66	nucleotide_off	25	0	No	Yes	No	No	4	3
144	6x29	8x50	nucleotide_off	50	0	No	No	Yes	Yes	6	9
145	1x28	1x29	nucleotide_off	25	0	No	No	No	No	0	6
146	2x41	4x39	nucleotide_off	2.5	0	Yes	No	No	No	4	3
147	5x30	E2	nucleotide_off	25	0	No	No	Yes	Yes	0	3
148	2x551	2x59	nucleotide_off	50	0	No	No	No	No	5	5
149	1x33	1x34	nucleotide_off	25	0	No	No	No	No	5	4
150	5x69	6x24	nucleotide_off	15	0	No	No	No	No	4	2
151	6x461	6x47	nucleotide_off	0	0	No	No	No	No	0	8
152	4x47	4x51	nucleotide_off	25	0	No	No	No	No	4	4
153	3x29	4x64	nucleotide_off	25	0	No	No	No	No	4	0
154	6x56	6x57	nucleotide_off	25	0	No	No	No	No	5	4
155	7x23	7x25	nucleotide_off	25	0	No	No	No	No	0	0
156	5x33	6x63	nucleotide_off	0	0	No	No	No	No	0	0
157	5x31	5x35	nucleotide_off	12.5	0	No	No	No	No	0	0
158	1x41	1x45	nucleotide_off	0	0	No	No	No	No	5	4
159	5x71	5x72	nucleotide_off	12.5	0	No	No	No	No	0	0
160	6x21	6x24	nucleotide_off	7.5	0	No	No	No	No	0	2
161	5x31	5x32	nucleotide_off	12.5	0	No	No	No	No	0	0
162	3x20	3x22	nucleotide_off	12.5	0	No	No	No	No	0	3
163	5x52	5x56	nucleotide_off	0	0	No	No	No	No	3	4
164	6x25	6x29	nucleotide_off	12.5	0	No	No	No	No	3	6
165	5x72	I3	nucleotide_off	2.5	0	No	No	No	No	0	4
166	I2x54	I2x55	nucleotide_off	2.5	0	No	No	No	No	4	5
167	4x41	4x44	nucleotide_off	0	0	No	No	No	No	5	3
168	6x30	I3	nucleotide_off	0	0	Yes	Yes	No	No	6	4
169	8x54	8x58	nucleotide_off	2.5	0	Yes	No	No	No	7	5
170	1x55	8x62	nucleotide_off	0	0	Yes	No	No	No	4	3
171	2x41	I1x51	nucleotide_off	7.5	0	Yes	No	No	No	4	7
172	6x22	6x26	nucleotide_off	5	0	No	No	No	No	3	3
173	2x65	2x67	nucleotide_off	0	0	No	No	No	No	4	0
174	4x51	4x55	nucleotide_off	0	0	No	No	No	No	4	4
175	6x58	7x29	nucleotide_off	0	0	Yes	No	No	No	4	0
176	8x61	8x64	nucleotide_off	2.5	0	No	No	No	No	6	5
177	6x23	6x26	nucleotide_off	2.5	0	No	No	No	No	4	3
178	1x27	1x30	nucleotide_off	2.5	0	No	No	No	No	0	5
179	8x64	8x65	nucleotide_off	0	0	No	No	No	No	5	0
180	5x70	5x73	nucleotide_off	0	0	No	No	No	No	0	0
181	1x35	1x39	Shared	100	100	Yes	Yes	Yes	Yes	5	6
182	1x35	2x64	Shared	100	100	Yes	Yes	Yes	No	5	3
183	1x35	7x35	Shared	100	100	Yes	Yes	No	Yes	5	3
184	1x38	7x39	Shared	100	100	No	No	No	Yes	5	5
185	1x39	2x57	Shared	100	100	Yes	Yes	Yes	Yes	6	6
186	1x39	7x42	Shared	100	100	Yes	Yes	No	Yes	6	7
187	1x42	7x39	Shared	100	75	No	No	No	Yes	7	5
188	1x43	2x57	Shared	100	100	No	No	Yes	Yes	5	6
189	1x45	7x47	Shared	100	50	No	No	No	No	4	6
190	1x50	2x50	Shared	100	100	No	No	No	Yes	9	9
191	1x50	7x50	Shared	100	100	No	No	No	No	9	9
192	1x52	8x54	Shared	100	100	No	No	Yes	No	7	7
193	1x55	1x59	Shared	100	50	Yes	No	No	No	4	5
194	1x57	2x44	Shared	100	100	No	No	Yes	No	8	5
195	1x60	I1x50	Shared	100	100	No	No	No	Yes	6	8
196	2x40	I1x50	Shared	100	100	No	Yes	No	Yes	8	8
197	2x37	2x40	Shared	100	100	No	No	No	Yes	7	8
198	2x39	3x49	Shared	100	100	No	No	Yes	No	8	9
199	2x42	3x45	Shared	100	25	Yes	Yes	No	No	8	7
200	2x42	4x46	Shared	100	75	Yes	Yes	No	No	8	8
201	2x45	3x42	Shared	100	50	No	No	No	No	9	8
202	2x45	4x46	Shared	100	100	No	No	No	No	9	8
203	2x46	7x49	Shared	100	100	No	Yes	Yes	Yes	9	9
204	2x50	7x46	Shared	100	100	No	Yes	No	No	9	9
205	2x50	7x49	Shared	100	100	No	Yes	Yes	Yes	9	9
206	2x53	2x56	Shared	100	100	No	No	No	No	8	6
207	2x53	7x46	Shared	100	100	No	No	No	No	8	9
208	2x57	7x42	Shared	100	100	Yes	Yes	No	Yes	6	7
209	2x59	3x28	Shared	100	100	No	No	No	No	5	6
210	E1x51	E2	Shared	100	6.25	No	No	Yes	Yes	4	3
211	3x22	E2	Shared	100	100	No	No	Yes	Yes	3	3
212	3x25	E2	Shared	100	100	No	No	Yes	Yes	9	3
213	3x25	E2x50	Shared	100	100	No	No	No	No	9	9
214	3x26	E2	Shared	100	100	No	No	Yes	Yes	5	3
215	3x30	4x61	Shared	100	100	No	No	No	Yes	6	5
216	3x34	4x54	Shared	100	100	No	No	No	No	5	3
217	3x34	4x57	Shared	100	100	No	No	No	No	5	6
218	3x37	4x56	Shared	100	100	Yes	Yes	No	Yes	6	5
219	3x37	5x461	Shared	100	100	Yes	Yes	Yes	Yes	6	8
220	3x38	4x50	Shared	100	100	No	No	Yes	No	7	9
221	3x38	4x53	Shared	100	100	No	No	No	No	7	8
222	3x41	4x49	Shared	100	100	No	No	No	No	4	7
223	3x47	5x58	Shared	100	100	No	No	Yes	Yes	9	9
224	3x49	I2x53	Shared	100	100	Yes	No	Yes	Yes	9	7
225	3x51	3x55	Shared	100	100	Yes	No	No	No	7	7
226	3x51	5x57	Shared	100	100	Yes	No	No	No	7	6
227	3x51	5x60	Shared	100	100	Yes	No	No	No	7	4
228	3x53	I2x53	Shared	100	100	No	No	Yes	Yes	8	7
229	3x56	I2x52	Shared	100	100	No	No	No	No	6	5
230	I2x53	I2x57	Shared	100	100	Yes	Yes	No	No	7	7
231	4x38	4x41	Shared	100	100	No	No	No	No	8	5
232	4x56	5x461	Shared	100	100	No	Yes	Yes	Yes	5	8
233	4x59	5x39	Shared	100	100	No	No	Yes	Yes	6	6
234	4x60	5x39	Shared	100	100	No	No	Yes	Yes	4	6
235	5x36	E2	Shared	100	100	No	No	Yes	Yes	5	3
236	5x39	E2	Shared	100	100	Yes	Yes	Yes	Yes	6	3
237	E2	E2	Shared	100	100	Yes	Yes	Yes	Yes	3	3
238	E2	E2x51	Shared	100	100	Yes	Yes	No	No	3	4
239	E2	E2x52	Shared	100	100	Yes	Yes	No	Yes	3	4
240	E2x52	Lig	Shared	100	100	No	Yes	Yes	Yes	4	0
241	E2	Lig	Shared	100	100	Yes	Yes	Yes	Yes	3	0
242	5x39	5x42	Shared	100	100	Yes	Yes	No	Yes	6	5
243	5x39	5x43	Shared	100	100	Yes	Yes	No	No	6	5
244	5x40	6x55	Shared	100	100	No	Yes	Yes	No	5	5
245	5x40	Lig	Shared	100	100	No	Yes	Yes	Yes	5	0
246	5x42	5x461	Shared	100	100	No	Yes	Yes	Yes	5	8
247	5x44	5x48	Shared	100	100	Yes	Yes	No	No	5	5
248	5x44	6x52	Shared	100	100	Yes	Yes	No	No	5	7
249	5x47	6x52	Shared	100	100	No	No	No	No	5	7
250	5x58	6x37	Shared	100	100	Yes	Yes	No	No	9	8
251	5x58	6x41	Shared	100	100	Yes	Yes	No	No	9	8
252	6x36	7x56	Shared	100	100	No	No	No	No	8	7
253	6x44	6x48	Shared	100	100	Yes	Yes	Yes	Yes	9	8
254	6x47	7x45	Shared	100	100	No	No	Yes	No	8	9
255	6x48	7x41	Shared	100	100	Yes	Yes	No	No	8	7
256	6x48	7x45	Shared	100	100	Yes	Yes	Yes	No	8	9
257	6x51	Lig	Shared	100	100	No	No	Yes	Yes	6	0
258	6x55	Lig	Shared	100	100	Yes	No	Yes	Yes	5	0
259	6x61	E3	Shared	100	100	No	No	No	Yes	4	3
260	7x31	7x35	Shared	100	100	No	No	No	Yes	3	3
261	7x34	Lig	Shared	100	50	No	No	Yes	Yes	4	0
262	7x38	Lig	Shared	100	100	No	No	Yes	Yes	5	0
263	E1x50	E1x52	Shared	100	100	No	No	No	No	3	7
264	7x45	7x49	Shared	100	100	Yes	No	Yes	Yes	9	9
265	3x40	6x48	Shared	100	100	No	Yes	Yes	Yes	8	8
266	2x42	4x45	Shared	75	100	Yes	Yes	No	No	8	5
267	3x40	5x50	Shared	75	87.5	No	Yes	No	No	8	8
268	8x47	8x50	Shared	50	100	No	No	Yes	Yes	8	9
269	3x54	5x61	Shared	75	50	No	No	No	No	9	9
270	5x37	6x59	Shared	50	31.25	No	No	Yes	No	3	4
271	2x52	3x35	Shared	75	100	No	No	No	No	6	7
272	3x37	4x53	Shared	50	25	Yes	Yes	No	No	6	8
273	5x49	5x50	Shared	50	100	No	No	No	No	4	8
274	1x39	2x61	Shared	50	100	Yes	Yes	No	No	6	6
275	6x51	7x37	Shared	47.5	37.5	No	No	No	No	6	5
276	1x56	8x50	Shared	52.5	6.25	No	No	Yes	Yes	8	9
277	5x44	5x45	Shared	50	100	Yes	Yes	No	No	5	4
278	5x41	6x59	Shared	50	100	No	No	Yes	No	4	4
279	1x36	2x61	Shared	50	100	No	No	No	No	5	6
280	5x37	6x55	Shared	50	100	No	No	Yes	No	3	5
281	5x46	5x461	Shared	50	100	No	No	Yes	Yes	5	8
282	3x47	5x57	Shared	50	50	No	No	No	No	9	6
283	5x411	6x59	Shared	50	100	No	No	Yes	No	4	4
284	1x57	2x40	Shared	50	100	No	No	No	Yes	8	8
285	3x21	E2	Shared	50	100	No	No	Yes	Yes	6	3
286	3x43	6x44	Shared	50	100	No	Yes	Yes	Yes	8	9
287	1x51	2x51	Shared	75	25	No	No	No	No	5	7
288	3x27	4x61	Shared	50	100	No	No	No	Yes	4	5
289	8x48	8x52	Shared	75	0	No	No	No	No	4	4
290	2x42	4x42	Shared	25	25	Yes	Yes	No	No	8	7
291	4x38	4x40	Shared	50	0	No	No	No	No	8	5
292	1x32	2x64	Shared	50	100	No	Yes	Yes	No	4	3
293	6x42	6x46	Shared	50	100	No	No	No	No	5	6
294	1x54	2x47	Shared	37.5	50	No	No	No	No	7	9
295	6x49	6x50	Shared	0	0	No	No	No	No	7	9
296	1x42	7x43	Shared	27.5	31.25	No	No	No	No	7	5
297	2x41	4x42	Shared	25	56.25	Yes	No	No	No	4	7
298	5x66	5x70	Shared	50	100	No	No	No	No	5	0
299	3x56	I2x50	Shared	12.5	0	No	No	No	No	6	8
300	1x46	7x47	Shared	12.5	56.25	No	No	No	No	8	6
301	6x50	7x40	Shared	25	0	No	No	No	No	9	7
302	6x39	6x43	Shared	25	100	No	No	No	Yes	6	6
303	3x44	5x53	Shared	0	100	No	No	No	No	7	6
304	8x51	8x55	Shared	25	0	No	No	No	No	8	5
305	1x34	1x38	Shared	25	50	No	No	No	No	4	5
306	8x60	8x61	Shared	37.5	50	No	No	No	No	6	6
307	7x51	7x55	Shared	2.5	50	No	No	No	No	7	6
308	1x48	1x49	Shared	0	0	No	No	No	No	4	8
309	6x24	6x28	Shared	25	25	No	No	No	No	2	3
310	I1x48	I1x51	Shared	22.5	25	No	No	No	No	6	7
311	5x55	5x59	Shared	15	6.25	No	No	No	No	5	3
312	I2x53	I2x54	Shared	25	100	Yes	Yes	No	No	7	4
313	8x56	8x60	Shared	17.5	6.25	No	No	No	No	5	6
314	4x48	4x52	Shared	0	6.25	No	No	No	No	1	4
315	1x37	1x40	Shared	12.5	0	No	No	No	No	5	4
316	4x48	4x51	Shared	12.5	50	No	No	No	No	1	4
317	5x48	5x52	Shared	7.5	6.25	No	No	No	No	5	3
318	1x29	1x32	nucleotide_on	0	100	No	No	No	Yes	6	4
319	1x31	7x32	nucleotide_on	0	100	No	No	No	No	4	1
320	1x32	7x35	nucleotide_on	0	100	No	Yes	No	Yes	4	3
321	1x35	7x38	nucleotide_on	0	100	Yes	Yes	No	No	5	5
322	1x35	7x39	nucleotide_on	0	100	Yes	Yes	No	Yes	5	5
323	1x46	7x46	nucleotide_on	0	100	No	No	No	No	8	9
324	1x53	8x50	nucleotide_on	0	100	No	No	Yes	Yes	9	9
325	1x54	2x44	nucleotide_on	0	100	No	No	Yes	No	7	5
326	1x60	8x53	nucleotide_on	0	100	No	No	No	Yes	6	6
327	8x49	I1x50	nucleotide_on	0	100	No	No	No	Yes	6	8
328	8x50	I1x50	nucleotide_on	0	100	Yes	Yes	No	Yes	9	8
329	8x53	I1x50	nucleotide_on	0	100	No	Yes	No	Yes	6	8
330	2x37	2x39	nucleotide_on	0	100	No	No	No	No	7	8
331	2x39	3x53	nucleotide_on	0	100	No	No	No	No	8	8
332	2x40	8x47	nucleotide_on	0	100	No	Yes	No	No	8	8
333	2x40	8x50	nucleotide_on	0	100	No	Yes	Yes	Yes	8	9
334	2x42	3x49	nucleotide_on	0	100	Yes	Yes	Yes	No	8	9
335	2x46	2x50	nucleotide_on	0	100	No	Yes	No	Yes	9	9
336	2x46	3x42	nucleotide_on	0	100	No	Yes	No	No	9	8
337	2x46	3x43	nucleotide_on	0	100	No	Yes	No	Yes	9	8
338	2x50	3x39	nucleotide_on	0	100	No	Yes	No	No	9	9
339	2x551	3x35	nucleotide_on	0	100	No	No	No	No	5	7
340	2x56	3x35	nucleotide_on	0	100	No	No	No	No	6	7
341	2x57	2x58	nucleotide_on	0	100	Yes	Yes	No	No	6	8
342	2x59	3x31	nucleotide_on	0	100	No	No	No	No	5	4
343	2x60	7x42	nucleotide_on	0	100	No	No	No	Yes	7	7
344	2x62	3x28	nucleotide_on	0	100	No	No	No	No	4	6
345	2x64	7x35	nucleotide_on	0	100	Yes	No	No	Yes	3	3
346	3x32	Lig	nucleotide_on	0	100	No	No	Yes	Yes	6	0
347	3x33	E2x52	nucleotide_on	0	100	No	No	No	Yes	4	4
348	3x33	5x39	nucleotide_on	0	100	No	No	Yes	Yes	4	6
349	3x33	5x43	nucleotide_on	0	100	No	No	No	No	4	5
350	3x36	Lig	nucleotide_on	0	100	No	No	Yes	Yes	6	0
351	3x37	3x41	nucleotide_on	0	100	Yes	Yes	No	No	6	4
352	3x40	6x44	nucleotide_on	0	100	No	Yes	Yes	Yes	8	9
353	3x43	7x49	nucleotide_on	0	100	No	Yes	Yes	Yes	8	9
354	3x43	7x53	nucleotide_on	0	100	No	Yes	Yes	Yes	8	9
355	3x46	3x50	nucleotide_on	0	100	No	No	Yes	No	9	9
356	3x46	7x53	nucleotide_on	0	100	No	No	Yes	Yes	9	9
357	3x50	5x58	nucleotide_on	0	100	Yes	No	Yes	Yes	9	9
358	3x50	7x53	nucleotide_on	0	100	Yes	No	Yes	Yes	9	9
359	3x52	3x56	nucleotide_on	0	100	No	No	No	No	5	6
360	3x54	5x64	nucleotide_on	0	100	No	No	No	No	9	5
361	4x38	4x39	nucleotide_on	0	100	No	No	No	No	8	3
362	4x52	5x461	nucleotide_on	0	100	No	No	Yes	Yes	4	8
363	4x56	5x42	nucleotide_on	0	100	No	Yes	No	Yes	5	5
364	4x59	4x60	nucleotide_on	0	100	No	No	No	No	6	4
365	4x59	E2	nucleotide_on	0	100	No	No	Yes	Yes	6	3
366	4x60	E2	nucleotide_on	0	100	No	No	Yes	Yes	4	3
367	5x42	E2	nucleotide_on	0	100	No	Yes	Yes	Yes	5	3
368	5x36	5x38	nucleotide_on	0	100	No	No	No	No	5	3
369	5x39	5x40	nucleotide_on	0	100	Yes	Yes	No	Yes	6	5
370	5x40	5x43	nucleotide_on	0	100	No	Yes	No	No	5	5
371	5x411	6x60	nucleotide_on	0	100	No	No	No	No	4	4
372	5x44	5x47	nucleotide_on	0	100	Yes	Yes	No	No	5	5
373	5x51	6x44	nucleotide_on	0	100	No	No	Yes	Yes	6	9
374	5x51	6x49	nucleotide_on	0	100	No	No	No	No	6	7
375	5x54	5x58	nucleotide_on	0	100	No	No	Yes	Yes	8	9
376	5x54	6x44	nucleotide_on	0	100	No	No	Yes	Yes	8	9
377	5x55	6x41	nucleotide_on	0	100	No	No	No	No	5	8
378	5x58	6x40	nucleotide_on	0	100	Yes	Yes	No	No	9	8
379	5x62	6x30	nucleotide_on	0	100	No	No	Yes	Yes	6	6
380	5x62	6x34	nucleotide_on	0	100	No	No	No	No	6	7
381	5x63	5x66	nucleotide_on	0	100	No	No	No	No	4	5
382	5x68	5x71	nucleotide_on	0	100	No	No	No	No	7	0
383	6x25	6x26	nucleotide_on	0	100	No	No	No	No	3	3
384	6x27	6x31	nucleotide_on	0	100	No	No	No	No	1	5
385	6x29	6x32	nucleotide_on	0	100	No	No	No	No	6	7
386	6x40	7x53	nucleotide_on	0	100	No	No	Yes	Yes	8	9
387	6x43	7x48	nucleotide_on	0	100	No	Yes	No	No	6	6
388	6x48	Lig	nucleotide_on	0	100	Yes	Yes	Yes	Yes	8	0
389	6x51	7x41	nucleotide_on	0	100	No	No	No	No	6	7
390	6x58	E3	nucleotide_on	0	100	Yes	No	No	Yes	4	3
391	E3	E3	nucleotide_on	0	100	No	Yes	No	Yes	3	3
392	7x34	E3	nucleotide_on	0	100	No	No	No	Yes	4	3
393	7x30	7x33	nucleotide_on	0	100	No	No	No	No	4	4
394	7x36	7x39	nucleotide_on	0	100	No	No	No	Yes	3	5
395	7x38	7x42	nucleotide_on	0	100	No	No	No	Yes	5	7
396	7x42	Lig	nucleotide_on	0	100	No	Yes	Yes	Yes	7	0
397	7x52	7x53	nucleotide_on	0	100	No	No	Yes	Yes	8	9
398	7x54	8x50	nucleotide_on	0	100	No	No	Yes	Yes	7	9
399	7x55	8x51	nucleotide_on	0	100	No	No	No	No	6	8
400	8x48	8x51	nucleotide_on	0	100	No	No	No	No	4	8
401	8x49	I1x49	nucleotide_on	0	100	No	No	No	No	6	6
402	5x69	6x29	nucleotide_on	0	100	No	No	No	No	4	6
403	2x53	2x54	nucleotide_on	0	75	No	No	No	No	8	7
404	7x32	7x36	nucleotide_on	0	75	No	No	No	No	1	3
405	3x44	5x50	nucleotide_on	0	75	No	No	No	No	7	8
406	1x50	2x51	nucleotide_on	0	50	No	No	No	No	9	7
407	6x54	E3	nucleotide_on	0	56.25	No	No	No	Yes	4	3
408	3x26	4x61	nucleotide_on	0	50	No	No	No	Yes	5	5
409	2x55	2x551	nucleotide_on	0	50	No	No	No	No	4	5
410	3x40	5x47	nucleotide_on	0	50	No	Yes	No	No	8	5
411	3x29	E2	nucleotide_on	0	75	No	No	Yes	Yes	4	3
412	2x63	3x28	nucleotide_on	0	50	No	No	No	No	3	6
413	7x30	E3	nucleotide_on	0	50	No	No	No	Yes	4	3
414	5x61	6x37	nucleotide_on	0	50	No	No	No	No	9	8
415	2x49	3x38	nucleotide_on	0	56.25	No	No	No	No	8	7
416	5x65	6x33	nucleotide_on	0	50	No	No	No	No	8	7
417	1x47	1x48	nucleotide_on	0	50	No	No	No	No	6	4
418	2x65	E1x50	nucleotide_on	0	50	No	No	No	No	4	3
419	3x23	3x27	nucleotide_on	0	50	No	No	No	No	1	4
420	8x52	8x53	nucleotide_on	0	50	No	No	No	Yes	4	6
421	3x34	4x58	nucleotide_on	0	0	No	No	No	No	5	4
422	6x39	7x56	nucleotide_on	0	50	No	No	No	No	6	7
423	2x63	E2x52	nucleotide_on	0	6.25	No	No	No	Yes	3	4
424	4x50	4x54	nucleotide_on	0	6.25	Yes	No	No	No	9	3
425	3x48	5x57	nucleotide_on	0	0	No	No	No	No	6	6
426	3x21	3x24	nucleotide_on	0	25	No	No	No	No	6	5
427	6x56	6x60	nucleotide_on	0	25	No	No	No	No	5	4
428	6x57	E3	nucleotide_on	0	25	No	No	No	Yes	4	3
429	7x55	8x54	nucleotide_on	0	25	No	No	Yes	No	6	7
430	4x63	E2	nucleotide_on	0	50	No	No	Yes	Yes	5	3
431	6x27	6x30	nucleotide_on	0	12.5	No	No	Yes	Yes	1	6
432	1x47	2x51	nucleotide_on	0	50	No	No	No	No	6	7
433	2x66	E2	nucleotide_on	0	50	No	No	Yes	Yes	3	3
434	2x66	E1x50	nucleotide_on	0	50	No	No	No	No	3	3
435	5x66	6x30	nucleotide_on	0	50	No	No	Yes	Yes	5	6
436	I2x55	I2x56	nucleotide_on	0	6.25	No	No	No	No	5	4
437	3x52	I2x53	nucleotide_on	0	0	No	No	Yes	Yes	5	7
438	2x38	I2x57	nucleotide_on	0	6.25	No	No	No	No	6	7
439	7x39	7x40	nucleotide_on	0	50	No	Yes	No	No	5	7
440	1x36	1x40	nucleotide_on	0	12.5	No	No	No	No	5	4
441	2x40	2x43	nucleotide_on	0	6.25	No	Yes	No	No	8	8
442	6x31	6x35	nucleotide_on	0	0	No	No	No	No	5	7
443	6x45	6x49	nucleotide_on	0	0	No	No	No	No	6	7
444	6x43	7x52	nucleotide_on	0	0	No	Yes	No	No	6	8
445	3x54	5x65	nucleotide_on	0	0	No	No	No	No	9	8
446	5x61	5x65	nucleotide_on	0	0	No	No	No	No	9	8
447	5x62	6x37	nucleotide_on	0	6.25	No	No	No	No	6	8
448	I2x52	I2x56	nucleotide_on	0	25	No	No	No	No	5	4
449	5x69	6x30	nucleotide_on	0	6.25	No	No	Yes	Yes	4	6
450	5x64	5x67	nucleotide_on	0	0	No	No	No	No	5	4
451	1x32	NT	nucleotide_on	0	0	No	Yes	Yes	No	4	0
452	1x33	7x35	nucleotide_on	0	25	No	No	No	Yes	5	3
453	5x73	6x26	nucleotide_on	0	25	No	No	No	No	0	3
454	6x42	6x43	nucleotide_on	0	0	No	No	No	Yes	5	6
455	1x55	1x58	nucleotide_on	0	0	Yes	No	No	No	4	3
456	1x52	1x55	nucleotide_on	0	0	No	No	Yes	No	7	4
457	4x40	4x43	nucleotide_on	0	25	No	No	No	No	5	1
458	1x57	I1x51	nucleotide_on	0	0	No	No	No	No	8	7
459	4x39	4x42	nucleotide_on	0	0	No	No	No	No	3	7
460	6x25	6x28	nucleotide_on	0	25	No	No	No	No	3	3
461	5x70	6x26	nucleotide_on	0	6.25	No	No	No	No	0	3
462	1x30	1x31	nucleotide_on	0	0	No	No	No	No	5	4
463	4x55	4x56	nucleotide_on	0	0	No	No	No	Yes	4	5
464	1x54	2x48	nucleotide_on	0	0	No	No	No	No	7	6
465	1x40	1x44	nucleotide_on	0	0	No	No	No	No	4	5
466	6x53	6x57	nucleotide_on	0	0	No	No	No	No	6	4
467	1x38	1x41	nucleotide_on	0	0	No	No	No	No	5	5
468	1x41	1x42	nucleotide_on	0	0	No	No	No	No	5	7
469	8x53	8x57	nucleotide_on	0	12.5	No	Yes	No	No	6	7
470	4x44	4x47	nucleotide_on	0	0	No	No	No	No	3	4
471	8x52	8x56	nucleotide_on	0	6.25	No	No	No	No	4	5
472	5x73	I3	nucleotide_on	0	12.5	No	No	No	No	0	4
473	5x56	5x60	nucleotide_on	0	6.25	No	No	No	No	4	4
474	5x67	5x71	nucleotide_on	0	6.25	No	No	No	No	4	0
475	5x69	5x72	nucleotide_on	0	6.25	No	No	No	No	4	0
476	4x43	4x44	nucleotide_on	0	0	No	No	No	No	1	3
477	1x27	2x65	nucleotide_on	0	6.25	No	No	No	No	0	4
478	4x61	4x62	nucleotide_on	0	6.25	No	Yes	No	No	5	4
479	8x55	8x58	nucleotide_on	0	0	No	No	No	No	5	5
480	1x28	1x33	nucleotide_on	0	0	No	No	No	No	0	5

Orange: nodes, hubs and links specific of nucleotide_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of nucleotide_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	nucleotide_off Avg Int. Strength	nucleotide_on Avg Int. Strength	nucleotide_off Num Of Links	nucleotide_on Num Of Links	ConSurf
1	1x55	nucleotide_off	0	0	4	3	4
2	2x41	nucleotide_off	0	0	4	1	4
3	2x44	nucleotide_off	0	0	4	2	5
4	2x64	nucleotide_off	0	0	4	3	3
5	3x49	nucleotide_off	17.5	0	5	3	9
6	3x50	nucleotide_off	42.5	0	5	3	9
7	3x51	nucleotide_off	37.5	0	4	3	7
8	4x50	nucleotide_off	0	0	4	2	9
9	6x55	nucleotide_off	0	0	4	3	5
10	6x58	nucleotide_off	0	0	4	1	4
11	6x59	nucleotide_off	32.5	0	4	3	4
12	7x45	nucleotide_off	0	0	4	3	9
13	8x54	nucleotide_off	0	0	4	2	7
14	NT	nucleotide_off	50	0	7	1	0
15	1x35	Shared	12.5	93.75	4	5	5
16	1x39	Shared	75	93.75	6	4	6
17	2x42	Shared	0	0	5	5	8
18	2x57	Shared	45	100	4	4	6
19	3x37	Shared	75	0	6	4	6
20	I2x53	Shared	0	50	4	5	7
21	E2	Shared	75	100	16	18	3
22	5x39	Shared	50	100	5	7	6
23	5x44	Shared	37.5	75	4	4	5
24	5x461	Shared	25	50	4	5	8
25	5x58	Shared	50	100	6	6	9
26	6x30	Shared	0	0	4	4	6
27	6x44	Shared	50	37.5	4	5	9
28	6x48	Shared	35	100	5	5	8
29	7x49	Shared	20	93.75	5	4	9
30	7x53	Shared	85	93.75	6	5	9
31	8x50	Shared	35	43.75	5	6	9
32	Lig	Shared	100	100	11	11	0
33	1x32	nucleotide_on	0	0	3	4	4
34	I1x50	nucleotide_on	17.5	43.75	2	5	8
35	2x40	nucleotide_on	10	75	3	6	8
36	2x46	nucleotide_on	0	0	1	4	9
37	2x50	nucleotide_on	20	100	3	5	9
38	3x40	nucleotide_on	0	50	2	4	8
39	3x43	nucleotide_on	0	31.25	1	4	8
40	4x56	nucleotide_on	0	6.25	2	4	5
41	4x61	nucleotide_on	0	0	2	4	5
42	E2x52	nucleotide_on	0	0	3	4	4
43	5x40	nucleotide_on	40	43.75	2	4	5
44	5x42	nucleotide_on	0	75	2	4	5
45	6x43	nucleotide_on	0	0	1	4	6
46	E3	nucleotide_on	22.5	68.75	3	8	3
47	7x35	nucleotide_on	0	50	3	5	3
48	7x39	nucleotide_on	0	50	3	5	5
49	7x42	nucleotide_on	40	93.75	2	5	7
50	8x53	nucleotide_on	0	0	2	4	6

Orange: nodes, hubs and links specific of nucleotide_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of nucleotide_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	nucleotide_off Recurrence	nucleotide_on Recurrence	nucleotide_off Hub1?	nucleotide_on Hub1?	nucleotide_off Hub2?	nucleotide_on Hub2?	ConSurf1	ConSurf2
1	1x35	1x39	nucleotide_off	38.3514	1.09402	Yes	Yes	Yes	Yes	5	6
2	1x39	7x39	nucleotide_off	17.8462	0	Yes	Yes	No	Yes	6	5
3	1x35	2x64	nucleotide_off	10.7384	4.42013	Yes	Yes	Yes	No	5	3
4	1x42	7x39	nucleotide_off	11.4509	5.18742	No	No	No	Yes	7	5
5	1x35	7x35	nucleotide_off	53.2999	7.9555	Yes	Yes	No	Yes	5	3
6	7x31	7x35	nucleotide_off	55.6044	1.28492	No	No	No	Yes	3	3
7	7x31	NT	nucleotide_off	56.5112	0	No	No	Yes	No	3	0
8	Lig	NT	nucleotide_off	66.4451	0	Yes	Yes	Yes	No	0	0
9	5x39	E2	nucleotide_off	51.4011	1.351	Yes	Yes	Yes	Yes	6	3
10	5x39	5x43	nucleotide_off	53.4329	0.201916	Yes	Yes	No	No	6	5
11	3x37	5x43	nucleotide_off	53.7431	0	Yes	Yes	No	No	6	5
12	3x36	3x37	nucleotide_off	100	0	No	No	Yes	Yes	6	6
13	3x36	6x48	nucleotide_off	99.7307	0	No	No	Yes	Yes	6	8
14	6x55	Lig	nucleotide_off	43.9149	8.53188	Yes	No	Yes	Yes	5	0
15	5x44	6x55	nucleotide_off	47.5285	0	Yes	Yes	Yes	No	5	5
16	5x44	6x52	nucleotide_off	47.2728	0.0110136	Yes	Yes	No	No	5	7
17	3x37	6x52	nucleotide_off	51.4045	0	Yes	Yes	No	No	6	7
18	7x49	7x53	nucleotide_off	89.6264	0	Yes	Yes	Yes	Yes	9	9
19	7x53	8x50	nucleotide_off	25.8301	0	Yes	Yes	Yes	Yes	9	9
20	8x50	8x54	nucleotide_off	17.4371	0	Yes	Yes	Yes	No	9	7
21	1x57	7x53	nucleotide_off	21.8995	0	No	No	Yes	Yes	8	9
22	1x57	2x44	nucleotide_off	12.7088	7.41217	No	No	Yes	No	8	5
23	2x43	7x53	nucleotide_off	57.5748	0	No	No	Yes	Yes	8	9
24	2x39	2x43	nucleotide_off	56.7839	0	No	No	No	No	8	8
25	2x39	3x50	nucleotide_off	43.1206	0	No	No	Yes	No	8	9
26	2x45	4x50	nucleotide_off	13.5031	0	No	No	Yes	No	9	9
27	3x50	6x30	nucleotide_off	43.1479	0	Yes	No	Yes	Yes	9	6
28	3x54	6x30	nucleotide_off	38.5184	0	No	No	Yes	Yes	9	6
29	3x54	5x61	nucleotide_off	37.506	9.55248	No	No	No	No	9	9
30	3x51	5x61	nucleotide_off	36.4867	0	Yes	No	No	No	7	9
31	3x51	5x57	nucleotide_off	25.6801	7.88208	Yes	No	No	No	7	6
32	7x54	8x54	nucleotide_off	13.8917	0	No	No	Yes	No	7	7
33	7x54	7x55	nucleotide_off	12.7361	0	No	No	No	No	7	6
34	6x36	7x55	nucleotide_off	10.377	0	No	No	No	No	8	6
35	E2	Lig	Shared	44.1876	56.5256	Yes	Yes	Yes	Yes	3	0
36	6x48	7x45	Shared	95.9296	41.1469	Yes	Yes	Yes	No	8	9
37	7x45	7x49	Shared	96.424	40.5301	Yes	No	Yes	Yes	9	9
38	2x50	7x49	Shared	15.4258	21.1425	No	Yes	Yes	Yes	9	9
39	2x39	3x49	Shared	12.7395	60.674	No	No	Yes	No	8	9
40	3x37	4x53	Shared	31.83	19.7915	Yes	Yes	No	No	6	8
41	3x38	4x53	Shared	26.3926	17.3428	No	No	No	No	7	8
42	3x38	4x50	Shared	25.2847	12.4234	No	No	Yes	No	7	9
43	2x45	4x46	Shared	12.6474	97.2686	No	No	No	No	9	8
44	2x42	4x46	Shared	11.4577	95.8919	Yes	Yes	No	No	8	8
45	3x47	5x57	Shared	24.5619	11.7809	No	No	No	No	9	6
46	3x47	5x58	Shared	20.0211	13.7193	No	No	Yes	Yes	9	9
47	1x35	7x39	nucleotide_on	0	14.6995	Yes	Yes	No	Yes	5	5
48	1x35	7x38	nucleotide_on	0	25.838	Yes	Yes	No	No	5	5
49	7x38	Lig	nucleotide_on	1.45224	26.6897	No	No	Yes	Yes	5	0
50	6x48	Lig	nucleotide_on	0	97.3788	Yes	Yes	Yes	Yes	8	0
51	2x50	7x46	nucleotide_on	9.47706	20.6322	No	Yes	No	No	9	9
52	1x50	2x50	nucleotide_on	4.98739	13.231	No	No	No	Yes	9	9
53	6x44	6x48	nucleotide_on	2.34881	55.2663	Yes	Yes	Yes	Yes	9	8
54	3x43	6x44	nucleotide_on	1.25452	61.0118	No	Yes	Yes	Yes	8	9
55	2x46	3x43	nucleotide_on	0	77.4111	No	Yes	No	Yes	9	8
56	2x46	3x42	nucleotide_on	0	100	No	Yes	No	No	9	8
57	2x45	3x42	nucleotide_on	0.323856	98.638	No	No	No	No	9	8
58	2x42	3x49	nucleotide_on	0	78.7107	Yes	Yes	Yes	No	8	9
59	2x37	2x39	nucleotide_on	0	58.8862	No	No	No	No	7	8
60	2x37	2x40	nucleotide_on	1.25452	57.2782	No	No	No	Yes	7	8
61	2x40	I1x50	nucleotide_on	6.61349	34.7149	No	Yes	No	Yes	8	8
62	8x53	I1x50	nucleotide_on	0	28.0664	No	Yes	No	Yes	6	8
63	8x52	8x53	nucleotide_on	0	25.3534	No	No	No	Yes	4	6
64	8x48	8x52	nucleotide_on	1.25452	18.9912	No	No	No	No	4	4
65	8x48	8x51	nucleotide_on	0	17.1959	No	No	No	No	4	8
66	7x55	8x51	nucleotide_on	0	12.5372	No	No	No	No	6	8
67	2x46	7x49	nucleotide_on	1.25452	29.9607	No	Yes	Yes	Yes	9	9
68	1x57	2x40	nucleotide_on	9.04411	12.8969	No	No	No	Yes	8	8
69	3x49	I2x53	nucleotide_on	3.30674	19.5602	Yes	No	Yes	Yes	9	7
70	2x53	7x46	nucleotide_on	8.26686	13.231	No	No	No	No	8	9
71	5x42	E2	nucleotide_on	0	34.6305	No	Yes	Yes	Yes	5	3
72	4x56	5x42	nucleotide_on	0	15.8413	No	Yes	No	Yes	5	5
73	3x37	4x56	nucleotide_on	1.24429	13.4843	Yes	Yes	No	Yes	6	5
74	5x42	5x461	nucleotide_on	1.50337	19.3509	No	Yes	Yes	Yes	5	8
75	3x37	5x461	nucleotide_on	1.82723	13.6055	Yes	Yes	Yes	Yes	6	8
76	3x43	7x53	nucleotide_on	0	41.3965	No	Yes	Yes	Yes	8	9
77	5x54	6x44	nucleotide_on	0	38.1512	No	No	Yes	Yes	8	9
78	5x54	5x58	nucleotide_on	0	37.3692	No	No	Yes	Yes	8	9
79	3x52	I2x53	nucleotide_on	0	11.6708	No	No	Yes	Yes	5	7
80	5x58	6x37	nucleotide_on	2.14768	50.2001	Yes	Yes	No	No	9	8
81	5x61	6x37	nucleotide_on	0	15.129	No	No	No	No	9	8
82	2x42	4x42	nucleotide_on	6.63053	16.1717	Yes	Yes	No	No	8	7
83	4x39	4x42	nucleotide_on	0	12.6657	No	No	No	No	3	7
84	4x38	4x39	nucleotide_on	0	10.8778	No	No	No	No	8	3
85	6x40	7x53	nucleotide_on	0	17.3685	No	No	Yes	Yes	8	9
86	5x58	6x40	nucleotide_on	0	17.0785	Yes	Yes	No	No	9	8
87	5x62	6x37	nucleotide_on	0	34.5167	No	No	No	No	6	8
88	5x62	6x30	nucleotide_on	0	31.0731	No	No	Yes	Yes	6	6
89	5x66	6x30	nucleotide_on	0	16.748	No	No	Yes	Yes	5	6
90	5x66	5x70	nucleotide_on	1.75905	12.9006	No	No	No	No	5	0
91	5x70	6x26	nucleotide_on	0	10.9512	No	No	No	No	0	3
92	7x52	7x53	nucleotide_on	0	10.0261	No	No	Yes	Yes	8	9
93	7x34	Lig	nucleotide_on	1.14543	10.1619	No	No	Yes	Yes	4	0
94	3x50	7x53	nucleotide_on	0	17.1959	Yes	No	Yes	Yes	9	9
95	3x50	5x58	nucleotide_on	0	16.983	Yes	No	Yes	Yes	9	9
96	7x42	Lig	nucleotide_on	0	12.3646	No	Yes	Yes	Yes	7	0
97	2x46	2x50	nucleotide_on	0	15.7091	No	Yes	No	Yes	9	9
98	3x43	7x49	nucleotide_on	0	11.5019	No	Yes	Yes	Yes	8	9

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
1x35	1x39	Shared	11.1655	22.6587	0	1	2	2
1x39	2x57	Shared	6.56125	6.23625	3	1	2	2
1x39	2x60	nucleotide_off	4.73925	0	3	1	2	2
1x39	7x42	Shared	9.5395	10.3856	3	1	2	1
2x57	7x42	Shared	4.76675	7.0425	3	1	2	1
E1x51	E2	Shared	4.525	0.404375	0	0	2	1
3x22	3x26	nucleotide_off	4.26175	0	1	0	2	2
3x22	E2	Shared	14.2975	18.6737	1	0	2	1
3x23	E2	nucleotide_off	3.75175	0	0	0	2	1
3x25	E2	Shared	4.97125	4.69625	1	1	2	1
3x26	E2	Shared	7.4095	9.13562	1	1	2	1
3x29	E2x52	nucleotide_off	5.437	0	0	0	2	1
3x32	3x33	nucleotide_off	4.92425	0	0	0	1	1
3x33	Lig	nucleotide_off	8.24775	0	0	1	1	0
3x36	6x48	nucleotide_off	5.734	0	0	0	1	1
3x37	5x43	nucleotide_off	5.9095	0	6	1	2	2
4x59	5x39	Shared	6.88475	3.28062	0	1	2	2
4x60	5x39	Shared	9.95525	12.7806	0	1	2	2
5x36	E2	Shared	11.7835	4.93625	1	1	2	1
5x39	E2	Shared	6.716	8.57875	1	1	2	1
E2	E2	Shared	48.5428	38.87	1	1	1	1
E2	E2x51	Shared	9.03225	7.8375	1	1	1	2
E2	E2x52	Shared	6.20425	12.47	1	1	1	1
E2x52	Lig	Shared	19.0433	31.6469	1	1	1	0
E2	Lig	Shared	8.12975	7.45687	1	1	1	0
5x39	5x42	Shared	4.204	5.48313	1	1	2	2
5x39	5x43	Shared	4.5525	3.19875	1	1	2	2
5x40	6x55	Shared	5.16225	3.32875	1	1	1	1
5x40	Lig	Shared	4.9415	3.92313	1	1	1	0
6x44	6x48	Shared	8.73	10.2712	5	1	2	1
6x44	7x45	nucleotide_off	4.48575	0	5	1	2	2
6x48	7x41	Shared	6.09025	5.5775	5	1	1	2
6x48	7x45	Shared	8.4535	9.11063	5	1	1	2
6x51	7x38	nucleotide_off	3.993	0	1	0	1	1
6x51	Lig	Shared	9.9775	9.46812	1	0	1	0
6x55	Lig	Shared	11.0292	7.74	1	1	1	0
6x58	Lig	nucleotide_off	5.0575	0	1	0	1	0
7x34	7x38	nucleotide_off	4.30175	0	1	1	1	1
7x34	Lig	Shared	8.50625	2.05813	1	1	1	0
7x38	Lig	Shared	6.4375	8.20687	1	1	1	0
E3	NT	nucleotide_off	5.4975	0	0	1	2	1
7x24	NT	nucleotide_off	3.8825	0	0	0	2	1
Lig	NT	nucleotide_off	6.5425	0	1	1	0	1
7x28	NT	nucleotide_off	7.35	0	0	0	2	1
7x31	NT	nucleotide_off	12.3687	0	0	0	2	1
3x36	3x37	nucleotide_off	6.81125	0	0	0	1	2
3x40	6x48	Shared	6.33125	16.8831	0	1	2	1
4x63	5x36	nucleotide_off	4.22	0	0	0	2	2
6x58	7x34	nucleotide_off	4.36	0	1	0	1	1
6x62	Lig	nucleotide_off	6.0725	0	0	0	1	0
5x44	6x55	nucleotide_off	4.08875	0	0	1	2	1
5x33	6x62	nucleotide_off	3.645	0	0	0	2	1
6x58	7x30	nucleotide_off	3.4525	0	1	0	1	2
6x51	7x37	Shared	3.3265	2.99875	1	0	1	2
E1x49	E2	nucleotide_off	3.23	0	0	0	2	1
5x37	6x55	Shared	3.18975	4.55937	0	0	2	1
3x21	E2	Shared	3.015	3.93	0	1	2	1
5x38	E2	nucleotide_off	2.73025	0	0	0	2	1
1x29	NT	nucleotide_off	2.5925	0	0	0	2	1
7x27	NT	nucleotide_off	2.57875	0	0	0	2	1
1x32	2x66	nucleotide_off	1.865	0	0	1	2	2
5x30	E2	nucleotide_off	1.6875	0	0	0	2	1
6x58	7x29	nucleotide_off	0.15625	0	1	0	1	2
1x29	1x32	nucleotide_on	0	5.95437	0	0	2	2
1x35	7x38	nucleotide_on	0	9.59562	0	1	2	1
2x60	7x42	nucleotide_on	0	3.38438	0	0	2	1
3x32	Lig	nucleotide_on	0	4.41687	0	0	1	0
3x33	E2x52	nucleotide_on	0	3.27313	0	1	1	1
3x33	5x39	nucleotide_on	0	4.68937	0	1	1	2
3x33	5x43	nucleotide_on	0	3.51562	0	1	1	2
3x36	Lig	nucleotide_on	0	10.9675	0	0	1	0
3x40	6x44	nucleotide_on	0	5.02313	0	1	2	2
4x59	4x60	nucleotide_on	0	4.04688	0	1	2	2
4x59	E2	nucleotide_on	0	3.4875	0	1	2	1
4x60	E2	nucleotide_on	0	3.34562	0	1	2	1
5x42	E2	nucleotide_on	0	4.635	0	1	2	1
5x36	5x38	nucleotide_on	0	5.2625	1	1	2	2
5x39	5x40	nucleotide_on	0	3.96563	1	1	2	1
5x40	5x43	nucleotide_on	0	6.04625	1	1	1	2
6x48	Lig	nucleotide_on	0	3.41375	5	1	1	0
6x51	7x41	nucleotide_on	0	5.34437	1	0	1	2
6x58	E3	nucleotide_on	0	5.08063	1	0	1	2
E3	E3	nucleotide_on	0	3.14188	0	1	2	2
7x34	E3	nucleotide_on	0	3.145	1	1	1	2
7x38	7x42	nucleotide_on	0	4.14563	1	1	1	1
7x42	Lig	nucleotide_on	0	6.5975	3	1	1	0
3x29	E2	nucleotide_on	0	2.82875	0	0	2	1
7x30	E3	nucleotide_on	0	2.76688	0	1	2	2
2x63	E2x52	nucleotide_on	0	2.35375	0	0	2	1
4x63	E2	nucleotide_on	0	2.12	0	0	2	1
2x66	E2	nucleotide_on	0	2.07125	0	1	2	1
1x32	NT	nucleotide_on	0	1.37	0	1	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	nucleotide_off	adenosine_off p2y_off
	nucleotide_on	adenosine_on

Network Difference
Value	nucleotide_off	nucleotide_on
I_min	3.69	3.12812
Number of Linked Nodes	299	266
Number of Specific Nodes	33 (11.04%)	0 (0.00%)
Number of Shared Nodes	266 (88.96%)	266 (100.00%)
Number of Links	317	300
Number of Specific Links	180 (56.78%)	163 (54.33%)
Number of Shared Links	137 (43.22%)	137 (45.67%)
Number of Hubs	32	36
Number of Specific Hubs	14 (43.75%)	18 (50.00%)
Number of Shared Hubs	18 (56.25%)	18 (50.00%)
Average % Shared Neighbours (Jaccard)	29.14
Average % Shared Neighbours (Otsuka)	38.02
Average % Shared Neighbours (Overlap Coefficient)	46.35
Average % Shared Cliques (k3-6)	53.13
Graphlets Similarity	0.49706

Paths Difference
Value	nucleotide_off	nucleotide_on
Number Of Nodes in MetaPath	46	59
Specific Nodes in MetaPath	20 (43.48%)	33 (55.93%)
Shared Nodes in MetaPath	266 (88.96%)	266 (88.96%)
Number Of Links MetaPath	46	64
Specific Links in MetaPath	34 (73.91%)	52 (81.25%)
Shared Links in MetaPath	137 (43.22%)	137 (43.22%)
Number of Shortest Paths	51958	58679
Length Of Smallest Path	3	3
Average Path Length	15.3811	13.8767
Length of Longest Path	36	33
Minimum Path Strength	0.426875	0.445312
Average Path Strength	5.84784	5.4213
Maximum Path Strength	17.5975	20.5575
Minimum Path Correlation	0.70025	0.703125
Average Path Correlation	0.904227	0.922394
Maximum Path Correlation	0.98625	0.989375
Minimum % Of Corr. Nodes	3.22581	3.44828
Average % Of Corr. Nodes	36.2992	44.5787
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	46.6888	44.8289
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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