Orange: nodes, hubs and links specific of nucleotide_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of nucleotide_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner nucleotide_on_gp Avg Int. Strength nucleotide_off Avg Int. Strength nucleotide_on_gp Num Of Links nucleotide_off Num Of Links ConSurf
1g.h1x1 nucleotide_on_gp00402
2g.l1x4 nucleotide_on_gp00508
3g.h2x11 nucleotide_on_gp41.66670406
4g.ctx3 nucleotide_on_gp1000609
5g.ctx6 nucleotide_on_gp20.83330506
6g.ctx14 nucleotide_on_gp33.33330409
7g.ctx15 nucleotide_on_gp16.66670409
8g.ctx16 nucleotide_on_gp1000808
91x32 nucleotide_on_gp00414
101x43 nucleotide_on_gp16.66670425
111x50 nucleotide_on_gp16.66670439
121x57 nucleotide_on_gp16.666750438
132x46 nucleotide_on_gp41.66670429
142x64 nucleotide_on_gp33.33330533
153x35 nucleotide_on_gp16.66670427
163x42 nucleotide_on_gp5050438
173x53 nucleotide_on_gp33.333325428
18I2x51 nucleotide_on_gp33.33330426
194x42 nucleotide_on_gp00427
205x40 nucleotide_on_gp5040.3846415
215x51 nucleotide_on_gp16.66670426
226x51 nucleotide_on_gp33.33330516
236x55 nucleotide_on_gp500435
246x59 nucleotide_on_gp2536.5385534
25E3 nucleotide_on_gp70.833369.2308733
267x39 nucleotide_on_gp16.66670425
277x42 nucleotide_on_gp37.50417
288x48 nucleotide_on_gp00414
298x54 nucleotide_on_gp00437
30G.S1.06 nucleotide_on_gp500409
31G.S1.07 nucleotide_on_gp00409
32G.S2.02 nucleotide_on_gp00406
33G.S2.03 nucleotide_on_gp00509
34G.S2.05 nucleotide_on_gp00403
35G.S2.06 nucleotide_on_gp33.33330508
36G.S2.08 nucleotide_on_gp58.33330505
37G.s2s3.01 nucleotide_on_gp00405
38G.S3.03 nucleotide_on_gp1000707
39G.S3.04 nucleotide_on_gp66.66670407
40G.S3.06 nucleotide_on_gp45.83330406
41G.H2.06 nucleotide_on_gp750409
42G.H2.07 nucleotide_on_gp1000709
43G.h2s4.01 nucleotide_on_gp1000509
44G.S4.02 nucleotide_on_gp250407
45G.S4.03 nucleotide_on_gp33.33330408
46G.S4.04 nucleotide_on_gp66.66670509
47G.s4h3.02 nucleotide_on_gp00409
48G.s4h3.04 nucleotide_on_gp95.83330608
49G.s4h3.05 nucleotide_on_gp16.66670409
50G.H3.01 nucleotide_on_gp00409
51G.H3.09 nucleotide_on_gp750409
52G.H3.13 nucleotide_on_gp33.33330406
53G.H3.17 nucleotide_on_gp91.66670605
54G.H3.18 nucleotide_on_gp66.66670409
55G.S5.02 nucleotide_on_gp00406
56G.S5.03 nucleotide_on_gp33.33330408
57G.S5.05 nucleotide_on_gp83.33330809
58G.HG.14 nucleotide_on_gp00405
59G.hgh4.02 nucleotide_on_gp33.33330408
60G.hgh4.05 nucleotide_on_gp79.16670506
61G.H4.03 nucleotide_on_gp00404
62G.H4.08 nucleotide_on_gp00403
63G.H4.10 nucleotide_on_gp20.83330406
64G.H4.15 nucleotide_on_gp750408
65G.S6.02 nucleotide_on_gp750508
66G.S6.05 nucleotide_on_gp33.33330605
67G.s6h5.02 nucleotide_on_gp00407
68G.H5.03 nucleotide_on_gp16.66670508
69G.H5.08 nucleotide_on_gp83.33330608
70G.H5.13 nucleotide_on_gp33.33330507
71G.H5.20 nucleotide_on_gp16.66670408
72G.H5.23 nucleotide_on_gp16.66670404
73G.H5.26 nucleotide_on_gp33.33330507
74b.1x1 nucleotide_on_gp00404
75b.1x7 nucleotide_on_gp00408
76b.1x11 nucleotide_on_gp00408
77b.1x15 nucleotide_on_gp00407
78b.1x19 nucleotide_on_gp16.66670406
79b.h2x1 nucleotide_on_gp16.66670405
80b.lhb1x3 nucleotide_on_gp00502
81b.lhb1x6 nucleotide_on_gp00503
82b.b1x4 nucleotide_on_gp16.66670407
83b.l1x3 nucleotide_on_gp1000609
84b.l1x6 nucleotide_on_gp12.50409
85b.b2x1 nucleotide_on_gp83.33330508
86b.b2x5 nucleotide_on_gp95.83330607
87b.b3x3 nucleotide_on_gp16.66670408
88b.l3x2 nucleotide_on_gp37.50509
89b.b4x3 nucleotide_on_gp33.33330407
90b.b4x5 nucleotide_on_gp16.66670407
91b.b4x6 nucleotide_on_gp1000709
92b.b5x2 nucleotide_on_gp00407
93b.b5x3 nucleotide_on_gp91.66670709
94b.b5x7 nucleotide_on_gp250407
95b.l5x1 nucleotide_on_gp66.66670508
96b.l5x5 nucleotide_on_gp1000709
97b.b6x5 nucleotide_on_gp66.66670506
98b.l6x5 nucleotide_on_gp16.66670404
99b.b7x1 nucleotide_on_gp66.66670504
100b.b8x4 nucleotide_on_gp83.33330406
101b.b9x3 nucleotide_on_gp00406
102b.l9x3 nucleotide_on_gp1000609
103b.l9x6 nucleotide_on_gp1000808
104b.b10x5 nucleotide_on_gp37.50409
105b.l10x1 nucleotide_on_gp500503
106b.b11x4 nucleotide_on_gp58.33330409
107b.l11x2 nucleotide_on_gp83.33330409
108b.b12x6 nucleotide_on_gp1000608
109b.b13x7 nucleotide_on_gp1000507
110b.l13x3 nucleotide_on_gp1000609
111b.l13x7 nucleotide_on_gp70.83330509
112b.b15x2 nucleotide_on_gp500406
113b.l15x2 nucleotide_on_gp66.66670509
114b.b16x4 nucleotide_on_gp87.50406
115b.b16x5 nucleotide_on_gp33.33330405
116b.b16x6 nucleotide_on_gp1000708
117b.b17x7 nucleotide_on_gp87.50408
118b.l17x3 nucleotide_on_gp1000609
119b.l17x6 nucleotide_on_gp58.33330509
120b.b18x3 nucleotide_on_gp79.16670408
121b.l18x1 nucleotide_on_gp83.33330706
122b.l18x2 nucleotide_on_gp750407
123b.b19x2 nucleotide_on_gp1000606
124b.b19x4 nucleotide_on_gp66.66670408
125b.l19x2 nucleotide_on_gp66.66670409
126b.b20x2 nucleotide_on_gp33.33330406
127b.b20x4 nucleotide_on_gp1000508
128b.b20x6 nucleotide_on_gp1000606
129b.b20x7 nucleotide_on_gp37.50409
130b.l20x2 nucleotide_on_gp250409
131b.b21x1 nucleotide_on_gp79.16670407
132b.b21x2 nucleotide_on_gp16.66670406
133b.b21x5 nucleotide_on_gp00404
134b.b21x7 nucleotide_on_gp91.66670605
135b.b22x5 nucleotide_on_gp83.33330507
136b.l22x5 nucleotide_on_gp95.83330509
137b.b23x6 nucleotide_on_gp1000607
138b.l23x1 nucleotide_on_gp16.66670406
139b.b24x4 nucleotide_on_gp16.66670406
140b.b24x6 nucleotide_on_gp41.66670408
141b.l24x3 nucleotide_on_gp00405
142b.l25x3 nucleotide_on_gp1000409
143b.l25x6 nucleotide_on_gp33.33330408
144b.b26x3 nucleotide_on_gp00406
145b.l27x1 nucleotide_on_gp1000709
146b.l27x2 nucleotide_on_gp79.16670409
147b.b28x2 nucleotide_on_gp00404
148b.b28x4 nucleotide_on_gp83.33330406
149b.b28x6 nucleotide_on_gp95.83330509
150G.HN.29 nucleotide_on_gp00400
1511x35 Shared95.833312.5545
1521x39 Shared70.833374.0385566
1531x60 Shared025446
1542x42 Shared79.166750458
1552x50 Shared5050649
1562x57 Shared33.333347.1154446
1573x34 Shared00445
1583x37 Shared37.5100456
1593x49 Shared16.666720.1923449
1603x50 Shared54.166739.4231549
161I2x53 Shared5022.1154447
1624x50 Shared16.66670549
163E2 Shared10010018163
1645x39 Shared41.6667100456
1655x58 Shared7550869
1666x48 Shared5081.7308768
1677x38 Shared83.33330545
1687x49 Shared37.512.5449
1698x50 Shared66.666737.5549
170Lig Shared10010015100
171E1 Shared33.333350440
1721x55 nucleotide_off00144
1732x44 nucleotide_off00355
1742x51 nucleotide_off00147
1752x63 nucleotide_off33.33330143
1763x51 nucleotide_off33.333350347
1773x54 nucleotide_off00349
1784x63 nucleotide_off050245
179E2x50 nucleotide_off33.33330249
180E2x52 nucleotide_off33.33330344
1815x461 nucleotide_off33.333325348
1826x24 nucleotide_off00140
1836x54 nucleotide_off00144
1847x31 nucleotide_off050343
1857x34 nucleotide_off33.33330344
1867x35 nucleotide_off58.33330343
1877x45 nucleotide_off012.5359
1887x53 nucleotide_off10087.5349
189NT nucleotide_off16.666750364
190I1 nucleotide_off5050150
   
Orange: nodes, hubs and links specific of nucleotide_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of nucleotide_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner nucleotide_on_gp Recurrence nucleotide_off Recurrence nucleotide_on_gp Hub1? nucleotide_off Hub1? nucleotide_on_gp Hub2? nucleotide_off Hub2? ConSurf1 ConSurf2
1g.h1x10 g.h1x13 nucleotide_on_gp10.10730NoNoNoNo91
2b.b17x3 g.h1x10 nucleotide_on_gp10.92320NoNoNoNo59
3b.l13x3 b.l13x7 nucleotide_on_gp11.27740YesNoYesNo99
4b.b11x5 b.l13x7 nucleotide_on_gp19.4770NoNoYesNo69
5b.b11x5 b.b14x3 nucleotide_on_gp19.99550NoNoNoNo65
6b.b10x2 b.b14x3 nucleotide_on_gp20.2560NoNoNoNo65
7b.b10x2 b.b10x4 nucleotide_on_gp20.51660NoNoNoNo66
8b.b10x4 b.b2x4 nucleotide_on_gp26.96060NoNoNoNo66
9b.b2x4 b.b6x5 nucleotide_on_gp27.21750NoNoYesNo66
10b.b3x1 b.b6x5 nucleotide_on_gp30.2020NoNoYesNo56
11b.b3x1 b.l2x3 nucleotide_on_gp30.43310NoNoNoNo58
12b.l2x3 b.l2x5 nucleotide_on_gp30.66570NoNoNoNo85
13b.l2x5 b.l4x2 nucleotide_on_gp31.08640NoNoNoNo54
14b.l4x2 g.ctx16 nucleotide_on_gp27.240NoNoYesNo48
15b.l4x1 g.ctx16 nucleotide_on_gp31.11230NoNoYesNo58
16b.b2x5 b.l4x1 nucleotide_on_gp31.3080YesNoNoNo75
17b.b2x3 b.b2x5 nucleotide_on_gp38.7940NoNoYesNo67
18b.b26x2 b.b2x3 nucleotide_on_gp59.77310NoNoNoNo76
19b.b26x1 b.b26x2 nucleotide_on_gp60.15440NoNoNoNo97
20b.b26x1 b.l27x1 nucleotide_on_gp60.34530NoNoYesNo99
21b.b2x1 b.l27x1 nucleotide_on_gp27.0460YesNoYesNo89
22b.b2x1 b.l3x1 nucleotide_on_gp27.84970YesNoNoNo89
23b.l3x1 b.l5x5 nucleotide_on_gp28.21870NoNoYesNo99
24G.h2s4.01 b.l5x5 nucleotide_on_gp17.00150YesNoYesNo99
25G.H2.07 G.h2s4.01 nucleotide_on_gp13.99370YesNoYesNo99
26G.H2.05 G.H2.07 nucleotide_on_gp43.3170NoNoYesNo79
27G.H2.05 b.l17x6 nucleotide_on_gp42.80690NoNoYesNo79
28b.l17x5 b.l17x6 nucleotide_on_gp44.10130NoNoYesNo69
29b.l17x5 b.l19x2 nucleotide_on_gp43.83710NoNoYesNo69
30b.b20x2 b.l19x2 nucleotide_on_gp36.70060YesNoYesNo69
31b.b20x2 b.b20x4 nucleotide_on_gp29.83620YesNoYesNo68
32b.b20x4 b.b20x6 nucleotide_on_gp29.03770YesNoYesNo86
33b.b17x7 b.b20x6 nucleotide_on_gp21.65490YesNoYesNo86
34b.b17x7 b.b21x1 nucleotide_on_gp19.49340YesNoYesNo87
35b.1x14 b.1x15 nucleotide_on_gp14.12630NoNoYesNo47
36b.1x11 b.1x14 nucleotide_on_gp13.5380YesNoNoNo84
37b.l5x5 b.l7x2 nucleotide_on_gp13.66420YesNoNoNo99
38G.H2.07 b.l7x2 nucleotide_on_gp13.95730YesNoNoNo99
39b.1x19 b.b21x1 nucleotide_on_gp10.57280YesNoYesNo67
40b.l26x5 g.ctx4 nucleotide_on_gp11.01590NoNoNoNo57
41g.ctx3 g.ctx4 nucleotide_on_gp10.78890YesNoNoNo97
42b.b21x5 b.b21x7 nucleotide_on_gp10.14570YesNoYesNo45
433x36 Lig nucleotide_on_gp47.51540NoNoYesYes60
443x43 7x49 nucleotide_on_gp61.9880NoNoYesYes89
453x43 7x53 nucleotide_on_gp71.61730NoNoNoYes89
463x50 7x53 nucleotide_on_gp71.81580YesYesNoYes99
473x50 G.H5.25 nucleotide_on_gp69.95650YesYesNoNo97
48G.H5.20 G.H5.25 nucleotide_on_gp70.15360YesNoNoNo87
49G.H5.20 G.H5.26 nucleotide_on_gp71.3570YesNoYesNo87
50G.H5.17 G.H5.26 nucleotide_on_gp77.89740NoNoYesNo57
51G.H5.13 G.H5.17 nucleotide_on_gp78.70890YesNoNoNo75
52G.H5.13 G.S6.02 nucleotide_on_gp82.86820YesNoYesNo78
53G.H5.10 G.S6.02 nucleotide_on_gp84.24760NoNoYesNo78
54G.H5.10 G.S5.03 nucleotide_on_gp42.97190NoNoYesNo78
55G.S5.03 G.S5.05 nucleotide_on_gp41.61980YesNoYesNo89
56G.S5.05 G.s6h5.01 nucleotide_on_gp98.8350YesNoNoNo99
57G.S5.07 G.s6h5.01 nucleotide_on_gp1000NoNoNoNo99
58G.S5.07 G.s5hg.01 nucleotide_on_gp99.97150NoNoNoNo99
59G.s4h3.02 G.s5hg.01 nucleotide_on_gp99.09020YesNoNoNo99
60G.HG.07 G.s4h3.02 nucleotide_on_gp99.87180NoNoYesNo99
61G.HG.07 G.s4h3.04 nucleotide_on_gp98.74220NoNoYesNo98
62G.HG.04 G.s4h3.04 nucleotide_on_gp98.9250NoNoYesNo88
63G.HG.04 G.s4h3.01 nucleotide_on_gp98.84850NoNoNoNo86
64G.S5.06 G.s4h3.01 nucleotide_on_gp98.82240NoNoNoNo96
65G.S5.04 G.S5.06 nucleotide_on_gp97.89380NoNoNoNo99
66G.H4.15 G.S5.04 nucleotide_on_gp97.90120YesNoNoNo89
67G.H3.09 G.H4.15 nucleotide_on_gp97.47190YesNoYesNo98
68G.H3.09 G.S4.04 nucleotide_on_gp96.99520YesNoYesNo99
69G.S1.07 G.S4.04 nucleotide_on_gp64.41670YesNoYesNo99
70G.S1.07 G.S4.02 nucleotide_on_gp60.5250YesNoYesNo97
71G.H3.18 G.S4.02 nucleotide_on_gp60.53340YesNoYesNo97
72G.H3.15 G.H3.18 nucleotide_on_gp60.35870NoNoYesNo89
73G.H3.15 G.H3.17 nucleotide_on_gp60.24480NoNoYesNo85
74G.H3.17 b.l27x1 nucleotide_on_gp39.95150YesNoYesNo59
75G.H5.10 G.S6.04 nucleotide_on_gp41.48690NoNoNoNo79
76G.S5.05 G.S6.04 nucleotide_on_gp41.51540YesNoNoNo99
773x53 G.H5.19 nucleotide_on_gp12.82510YesNoNoNo87
78G.H5.15 G.H5.19 nucleotide_on_gp13.02810NoNoNoNo87
79G.H5.15 I2x51 nucleotide_on_gp13.24420NoNoYesNo86
80G.S1.04 G.S3.03 nucleotide_on_gp16.15180NoNoYesNo77
81G.S1.04 G.S4.03 nucleotide_on_gp15.64620NoNoYesNo78
82G.S4.03 G.S5.05 nucleotide_on_gp16.27560YesNoYesNo89
83b.b22x1 b.b22x2 nucleotide_on_gp10.24610NoNoNoNo88
84b.b22x1 b.l25x6 nucleotide_on_gp10.1860NoNoYesNo88
85b.b4x2 b.b5x8 nucleotide_on_gp10.53190NoNoNoNo85
86b.b5x7 b.b5x8 nucleotide_on_gp10.29630YesNoNoNo75
87b.b4x2 b.l3x2 nucleotide_on_gp12.17870NoNoYesNo89
88G.H2.07 b.l9x6 nucleotide_on_gp14.33040YesNoYesNo98
89G.H2.04 G.H2.07 nucleotide_on_gp32.51860NoNoYesNo99
90G.H2.04 G.H3.08 nucleotide_on_gp32.47870NoNoNoNo99
91G.H3.08 G.S4.04 nucleotide_on_gp32.630NoNoYesNo99
92b.l1x3 b.l3x2 nucleotide_on_gp13.09150YesNoYesNo99
93b.b4x6 b.l1x3 nucleotide_on_gp13.55110YesNoYesNo99
94b.l11x1 b.l9x6 nucleotide_on_gp13.01240NoNoYesNo98
95b.b11x6 b.l11x1 nucleotide_on_gp13.73650NoNoNoNo99
96b.b11x6 b.l9x3 nucleotide_on_gp12.14490NoNoYesNo99
97b.b19x4 b.l17x3 nucleotide_on_gp10.39070YesNoYesNo89
98b.l23x1 b.l25x6 nucleotide_on_gp19.23460YesNoYesNo68
99b.l21x7 b.l23x1 nucleotide_on_gp19.06260NoNoYesNo56
100b.l21x7 b.l23x2 nucleotide_on_gp18.82160NoNoNoNo58
101b.b23x6 b.l23x2 nucleotide_on_gp18.09980YesNoNoNo78
102b.b21x7 b.b24x6 nucleotide_on_gp14.40170YesNoYesNo58
103b.b23x6 b.b24x6 nucleotide_on_gp15.18540YesNoYesNo78
104b.b3x2 b.b4x6 nucleotide_on_gp21.14990NoNoYesNo59
105b.b2x3 b.b3x2 nucleotide_on_gp20.79540NoNoNoNo65
106G.H3.17 b.l25x6 nucleotide_on_gp19.68070YesNoYesNo58
1073x36 6x48 Shared47.368249.8171NoNoYesYes68
1086x48 7x45 Shared56.897238.049YesYesNoYes89
1097x45 7x49 Shared57.68934.5331NoYesYesYes99
110E2 Lig Shared15.522266.4156YesYesYesYes30
1111x35 1x39 nucleotide_off0.044620350.0815YesYesYesYes56
1121x39 2x57 nucleotide_off0.021198329.3117YesYesYesYes66
1131x35 7x35 nucleotide_off0.011266360.4012YesYesNoYes53
1147x31 7x35 nucleotide_off1.1220321.7439NoYesNoYes33
1157x31 Lig nucleotide_off021.9502NoYesYesYes30
1165x39 E2 nucleotide_off3.950398.4973YesYesYesYes63
1175x39 5x42 nucleotide_off0.61223299.8552YesYesNoNo65
1185x42 5x461 nucleotide_off0100NoNoNoYes58
1193x37 5x461 nucleotide_off1.5348899.7031YesYesNoYes68
1203x37 4x53 nucleotide_off095.8431YesYesNoNo68
1213x38 4x53 nucleotide_off0.31204693.3809NoNoNoNo78
1223x38 4x50 nucleotide_off0.62394393.0405NoNoYesYes79
1232x45 4x50 nucleotide_off0.0020753685.0708NoNoYesYes99
1242x45 4x46 nucleotide_off0.62394388.3912NoNoNoNo98
1252x42 4x46 nucleotide_off087.9567YesYesNoNo88
1262x42 3x46 nucleotide_off084.7449YesYesNoNo89
1273x46 6x37 nucleotide_off084.4444NoNoNoNo98
1285x58 6x37 nucleotide_off1.2604983.9954YesYesNoNo98
1293x47 5x58 nucleotide_off0.31530777.713NoNoYesYes99
1303x47 5x57 nucleotide_off078.5169NoNoNoNo96
1313x51 5x57 nucleotide_off0.68946577.9375NoYesNoNo76
1323x51 5x61 nucleotide_off072.3974NoYesNoNo79
1333x54 5x61 nucleotide_off0.31263968.4108NoYesNoNo99
1343x54 6x30 nucleotide_off058.2648NoYesNoNo96
1353x50 6x30 nucleotide_off056.2914YesYesNoNo96
1362x39 3x50 nucleotide_off044.1829NoNoYesYes89
1372x37 2x39 nucleotide_off039.0738NoNoNoNo78
1382x37 2x40 nucleotide_off2.7307337.39NoNoNoNo78
1391x57 2x40 nucleotide_off023.2502YesNoNoNo88
1401x57 2x44 nucleotide_off0.95155415.7874YesNoNoYes85
1417x35 7x38 nucleotide_off1.6973541.0689NoYesYesYes35
1427x38 Lig nucleotide_off3.2590621.3347YesYesYesYes50
1437x38 E2x52 nucleotide_off020.1543YesYesNoYes54
144E2 E2x52 nucleotide_off0.015565221.5012YesYesNoYes34
1453x36 3x37 nucleotide_off050.7296NoNoYesYes66
1462x50 7x49 nucleotide_off4.1940118.5465YesYesYesYes99
1472x40 I1x50 nucleotide_off2.1355515.0234NoNoNoNo88
1488x50 I1x50 nucleotide_off010.3849YesYesNoNo98
1493x54 5x65 nucleotide_off012.916NoYesNoNo98
1505x65 6x31 nucleotide_off011.75NoNoNoNo85
1516x40 7x49 nucleotide_off011.0113NoNoYesYes89
1521x42 2x57 nucleotide_off018.7529NoNoYesYes76
1531x42 7x47 nucleotide_off0.93154110.7579NoNoNoNo76
154Lig NT nucleotide_off011.0403YesYesNoYes04

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
1x351x39Shared14.707111.340222
1x352x64Shared7.785774.724170221
1x357x35Shared6.120111.990222
1x392x57Shared6.378085.276670222
1x392x60nucleotide_off5.2126900222
1x397x42Shared9.638858.428750221
2x63E2x50nucleotide_off3.8554801022
E1x51E2nucleotide_off4.5236501021
3x223x26nucleotide_off7.2709601222
3x22E2Shared16.136515.73421221
3x23E2nucleotide_off4.38500021
3x25E2Shared6.465582.963331221
3x25E2x50Shared7.287.281222
3x26E2Shared8.862884.919581221
3x29E2x52Shared10.00053.597080211
3x323x33nucleotide_off5.3989400021
3x334x60nucleotide_off4.5900011
3x366x48Shared4.945873.138750012
3x374x56nucleotide_off4.1057707012
3x375x461Shared8.28994.196677012
4x565x461Shared6.936835.406677022
4x605x39Shared9.856158.190420012
4x63E2Shared6.13252.07251221
5x36E2Shared15.3519.081221
5x39E2Shared6.955385.0951221
E2E2Shared65.861354.70331211
E2E2x51Shared13.14310.50541212
E2E2x52Shared6.302128.783331211
E2x52LigShared20.804318.65081210
E2LigShared12.84838.525831210
5x376x59nucleotide_off4.3709600022
5x395x43nucleotide_off5.5805801222
5x406x55Shared6.639714.824170211
6x487x41Shared5.387213.276676322
6x51LigShared8.311353.698750210
6x547x37Shared5.3152.039170022
6x55LigShared6.402885.133750210
6x58Lignucleotide_off8.0980801210
7x317x35Shared8.899236.866671012
7x347x38Shared6.899334.343331211
7x34LigShared4.375485.317921210
7x38LigShared6.652127.710831210
1x317x35nucleotide_off9.4901901022
7x31Lignucleotide_off6.2268301010
7x357x38Shared4.884422.969171221
E3NTShared10.9952.811670221
7x24NTShared5.0352.123330021
LigNTnucleotide_off13.08501201
7x28NTShared5.01540021
7x31NTnucleotide_off10.57501011
E1NTnucleotide_off4.50500221
1x317x31nucleotide_off5.07501021
1x32E1nucleotide_off8.800022
2x632x64Shared4.9653.303331021
2x63E1nucleotide_off4.3701022
E1x49E2Shared6.463.448331021
3x29E2x50nucleotide_off5.5700212
3x363x37nucleotide_off7.03500011
3x376x52nucleotide_off3.8107012
4x635x36nucleotide_off8.4401222
7x38E2x52nucleotide_off4.76501211
5x336x62nucleotide_off7.2900021
6x587x34Shared8.7211.2151211
6x62LigShared12.1454.240010
1x362x64nucleotide_off3.5173100021
3x374x53nucleotide_off3.3108707012
5x376x55Shared3.236062.687920021
3x21E2Shared3.0152.104170021
1x422x57nucleotide_off2.9458700022
5x38E2nucleotide_off2.6520200021
3x294x64nucleotide_off2.63500212
6x547x34nucleotide_off2.3627900021
5x336x63nucleotide_off2.07500022
1x322x64nucleotide_on_gp03.663330021
1x357x38nucleotide_on_gp04.257080221
2x577x42nucleotide_on_gp03.1750221
3x33Lignucleotide_on_gp08.423330010
3x36Lignucleotide_on_gp05.366670010
3x373x41nucleotide_on_gp03.137087012
3x375x43nucleotide_on_gp03.77257012
5x365x38nucleotide_on_gp03.08251222
5x40Lignucleotide_on_gp03.922080210
6x517x37nucleotide_on_gp03.41250212
6x517x38nucleotide_on_gp03.084170211
6x517x41nucleotide_on_gp05.042080212
E3E3nucleotide_on_gp03.803750222
7x42Lignucleotide_on_gp03.172920210
1x327x31nucleotide_on_gp03.308750021
6x516x52nucleotide_on_gp03.160830212
2x64Lignucleotide_on_gp02.894580010
3x37Lignucleotide_on_gp03.460427010
2x603x32nucleotide_on_gp02.931670022
2x533x32nucleotide_on_gp04.120022
2x533x36nucleotide_on_gp02.896670021
2x602x64nucleotide_on_gp02.783330021
3x29Lignucleotide_on_gp02.780210
4x64E2nucleotide_on_gp05.9650021
5x365x40nucleotide_on_gp03.41221
5x406x59nucleotide_on_gp03.696670212
6x556x59nucleotide_on_gp02.883330212
6x586x62nucleotide_on_gp05.2651211
4x60Lignucleotide_on_gp04.048330010
1x287x31nucleotide_on_gp02.750021
6x58E3nucleotide_on_gp02.702081212
5x33E2nucleotide_on_gp02.363330021
1x427x42nucleotide_on_gp02.315420021
E1E2nucleotide_on_gp02.118330221
6x63E2nucleotide_on_gp01.870021
3x223x23nucleotide_on_gp01.718751222
5x30E2nucleotide_on_gp00.240021

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
nucleotide_on_gp adenosine_on_gp
p2y_on_gp
nucleotide_off adenosine_off
p2y_off
Network Difference
Value nucleotide_on_gp nucleotide_off
Imin 2.77792 3.76933
Number of Linked Nodes 942 292
Number of Specific Nodes 658 (69.85%) 8  (2.74%)
Number of Shared Nodes 284 (30.15%) 284  (97.26%)
Number of Links 1098 315
Number of Specific Links 938 (85.43%) 155  (49.21%)
Number of Shared Links 160 (14.57%) 160  (50.79%)
Number of Hubs 171 40
Number of Specific Hubs 150 (87.72%) 19  (47.50%)
Number of Shared Hubs 21 (12.28%) 21  (52.50%)
Average % Shared Neighbours (Jaccard) 11.95
Average % Shared Neighbours (Otsuka) 14.68
Average % Shared Neighbours (Overlap Coefficient) 17.39
Average % Shared Cliques (k3-6) 75.85
Graphlets Similarity 0.544238
Paths Difference
Value nucleotide_on_gp nucleotide_off
Number Of Nodes in MetaPath 113 47
Specific Nodes in MetaPath 106 (93.81%) 40  (85.11%)
Shared Nodes in MetaPath 284 (30.15%) 284  (30.15%)
Number Of Links MetaPath 110 48
Specific Links in MetaPath 106 (96.36%) 44  (91.67%)
Shared Links in MetaPath 160 (14.57%) 160  (14.57%)
Number of Shortest Paths 1199796 50535
Length Of Smallest Path 3 3
Average Path Length 33.152 18.6618
Length of Longest Path 72 42
Minimum Path Strength 0.410139 0.426875
Average Path Strength 5.37302 5.51434
Maximum Path Strength 17.4646 16.6579
Minimum Path Correlation 0.70125 0.700673
Average Path Correlation 0.967786 0.914217
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 1.51515 2.63158
Average % Of Corr. Nodes 35.8083 36.6939
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 48.4679 46.2158
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download nucleotide_off_on_gp.zip<



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