Orange: nodes, hubs and links specific of p2y1_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of p2y1_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner p2y1_on_gp Avg Int. Strength p2y1_off Avg Int. Strength p2y1_on_gp Num Of Links p2y1_off Num Of Links ConSurf
11x35 p2y1_on_gp4.162510.6733436
21x56 p2y1_on_gp5.582.73527
31x60 p2y1_on_gp6.04253.2435
42x37 p2y1_on_gp4.3158.83417
52x63 p2y1_on_gp8.3359.76635
62x64 p2y1_on_gp6.6357.9635
73x28 p2y1_on_gp5.086.43333434
83x29 p2y1_on_gp7.2133311.4267635
93x43 p2y1_on_gp4.48752.77418
103x46 p2y1_on_gp5.40254.605428
113x49 p2y1_on_gp9.28510.6833438
12I2x51 p2y1_on_gp4.46255.64415
134x50 p2y1_on_gp7.418.69667439
14E2.T201 p2y1_on_gp9.357.67423
15E2x50 p2y1_on_gp9.202510.93439
16E2x51 p2y1_on_gp8.7185.23333534
17E2x52 p2y1_on_gp8.9811.2333536
18E2.T205 p2y1_on_gp9.0357.63667435
195x33 p2y1_on_gp3.739.365424
206x31 p2y1_on_gp7.026.705626
216x49 p2y1_on_gp5.033.58425
226x52 p2y1_on_gp9.187514.4067438
236x54 p2y1_on_gp2.62256.03435
246x55 p2y1_on_gp5.5266.98526
256x62 p2y1_on_gp8.587515.1133435
266x63 p2y1_on_gp4.14756.325423
277x34 p2y1_on_gp7.4033311.3967634
287x35 p2y1_on_gp8.9312.8467535
297x38 p2y1_on_gp6.40510.41635
307x54 p2y1_on_gp3.8360506
31G.HN.11 p2y1_on_gp2.110402
32G.HN.43 p2y1_on_gp5.36250408
33G.hns1.02 p2y1_on_gp5.24250403
34G.S1.06 p2y1_on_gp5.94750408
35G.H1.01 p2y1_on_gp4.3550409
36G.H1.04 p2y1_on_gp10.86750407
37G.H1.07 p2y1_on_gp3.76750409
38G.H1.12 p2y1_on_gp5.80250408
39G.S2.04 p2y1_on_gp7.9380506
40G.S3.03 p2y1_on_gp4.5050407
41G.S3.04 p2y1_on_gp9.5150407
42G.S3.05 p2y1_on_gp5.91250407
43G.S3.07 p2y1_on_gp5.5760509
44G.H2.05 p2y1_on_gp9.62750407
45G.H2.06 p2y1_on_gp7.031670609
46G.H2.07 p2y1_on_gp6.288570709
47G.h2s4.01 p2y1_on_gp7.6340509
48G.S4.03 p2y1_on_gp5.3040508
49G.S4.04 p2y1_on_gp7.34750409
50G.s4h3.04 p2y1_on_gp8.1920508
51G.H3.13 p2y1_on_gp5.8950405
52G.H3.15 p2y1_on_gp3.450608
53G.H3.17 p2y1_on_gp7.4040505
54G.H3.18 p2y1_on_gp4.6760509
55G.S5.05 p2y1_on_gp6.8540509
56G.s5hg.01 p2y1_on_gp3.86250409
57G.hgh4.05 p2y1_on_gp6.6650406
58G.h4s6.13 p2y1_on_gp3.99750407
59G.S6.02 p2y1_on_gp8.050508
60G.S6.05 p2y1_on_gp7.0250405
61G.H5.03 p2y1_on_gp7.3360508
62G.H5.15 p2y1_on_gp3.450608
63G.H5.17 p2y1_on_gp6.560405
64G.H5.23 p2y1_on_gp8.240604
65b.1x3 p2y1_on_gp5.76750401
66b.lhb1x11 p2y1_on_gp4.39750404
67b.b1x3 p2y1_on_gp4.84750407
68b.l1x3 p2y1_on_gp6.2650609
69b.l1x6 p2y1_on_gp7.6850409
70b.b2x1 p2y1_on_gp9.520508
71b.b2x5 p2y1_on_gp9.52750407
72b.b3x3 p2y1_on_gp4.7950408
73b.l3x2 p2y1_on_gp7.720409
74b.b4x5 p2y1_on_gp4.9020507
75b.b4x6 p2y1_on_gp8.840709
76b.l4x1 p2y1_on_gp4.61750405
77b.l4x2 p2y1_on_gp9.05250404
78b.b5x3 p2y1_on_gp6.8550609
79b.b5x5 p2y1_on_gp5.440505
80b.l5x1 p2y1_on_gp4.52250408
81b.l5x5 p2y1_on_gp7.731430709
82b.b6x5 p2y1_on_gp4.72750406
83b.b7x1 p2y1_on_gp7.94750404
84b.b8x3 p2y1_on_gp5.31750406
85b.b8x4 p2y1_on_gp6.4680506
86b.l9x3 p2y1_on_gp10.01250409
87b.l9x6 p2y1_on_gp6.655710708
88b.b10x5 p2y1_on_gp5.2850409
89b.l10x1 p2y1_on_gp4.23750403
90b.b11x1 p2y1_on_gp6.59250405
91b.b11x4 p2y1_on_gp5.05750409
92b.b11x5 p2y1_on_gp5.59750406
93b.l11x2 p2y1_on_gp6.2550409
94b.b12x3 p2y1_on_gp4.47750408
95b.b12x6 p2y1_on_gp10.6440508
96b.l12x1 p2y1_on_gp4.64750406
97b.b13x7 p2y1_on_gp7.7840507
98b.l13x3 p2y1_on_gp7.97250409
99b.l13x7 p2y1_on_gp5.30509
100b.b15x3 p2y1_on_gp3.3450409
101b.l15x1 p2y1_on_gp7.2150407
102b.l15x2 p2y1_on_gp7.55750409
103b.b16x4 p2y1_on_gp6.311670606
104b.b16x6 p2y1_on_gp9.2220508
105b.b17x5 p2y1_on_gp5.9060507
106b.b17x7 p2y1_on_gp9.22750408
107b.l17x3 p2y1_on_gp8.368570709
108b.l17x6 p2y1_on_gp10.7150409
109b.b18x3 p2y1_on_gp5.09750408
110b.l18x2 p2y1_on_gp5.66750407
111b.b19x2 p2y1_on_gp9.77250406
112b.b19x4 p2y1_on_gp6.27750408
113b.l19x1 p2y1_on_gp5.450409
114b.l19x2 p2y1_on_gp8.330409
115b.b20x2 p2y1_on_gp5.6140506
116b.b20x4 p2y1_on_gp8.8960508
117b.b20x6 p2y1_on_gp7.9420506
118b.l20x2 p2y1_on_gp6.840409
119b.b21x2 p2y1_on_gp5.1650406
120b.b21x7 p2y1_on_gp5.1780505
121b.l21x5 p2y1_on_gp4.34250404
122b.l21x7 p2y1_on_gp3.74250405
123b.b22x4 p2y1_on_gp3.750405
124b.l22x5 p2y1_on_gp8.260409
125b.b23x1 p2y1_on_gp3.9750405
126b.b23x2 p2y1_on_gp6.0550406
127b.b23x6 p2y1_on_gp6.9640507
128b.l23x1 p2y1_on_gp9.0150406
129b.l23x2 p2y1_on_gp5.73750408
130b.b24x6 p2y1_on_gp7.350408
131b.l24x3 p2y1_on_gp5.1450405
132b.l25x3 p2y1_on_gp12.5580509
133b.l25x6 p2y1_on_gp13.17250408
134b.b27x5 p2y1_on_gp7.79750409
135b.l27x1 p2y1_on_gp10.74750809
136b.l27x2 p2y1_on_gp10.150409
137b.b28x4 p2y1_on_gp10.79750406
138b.b28x6 p2y1_on_gp9.0960509
139b.b28x7 p2y1_on_gp6.7550409
140g.ctx3 p2y1_on_gp5.5160509
141g.ctx4 p2y1_on_gp5.02250407
142g.ctx6 p2y1_on_gp3.06750406
143g.ctx14 p2y1_on_gp6.73250409
144g.ctx15 p2y1_on_gp7.54750409
145g.ctx16 p2y1_on_gp6.368890908
1461x39 Shared4.5067.29167567
1471x57 Shared7.445.15446
148I1.W83 Shared8.569.1725546
1492x39 Shared5.8487.63547
1502x42 Shared4.857.65547
1512x53 Shared8.298.1575447
1522x57 Shared3.98254.2525447
153E1x50 Shared7.378338.75333668
154E1x52 Shared4.12756.966457
1553x42 Shared6.69211.23547
1563x50 Shared9.38256.5675449
1573x51 Shared7.69755.76167467
158E2.R195 Shared10.847.55551
1595x36 Shared7.7748.516554
1605x39 Shared9.577.5225445
1615x58 Shared6.931678.62669
1626x48 Shared7.79.7275548
1637x53 Shared6.264.945469
164Lig Shared8.17510.82781290
1652x43 p2y1_off3.733.966258
1662x44 p2y1_off9.443336.198355
1672x50 p2y1_off13.9757.29249
1682x51 p2y1_off5.566674.772357
169E1.T115 p2y1_off4.537.0275344
1703x30 p2y1_off12.2555.37246
1713x32 p2y1_off7.566675.8325347
1723x37 p2y1_off5.4058.46257
1733x52 p2y1_off3.823334.308355
1744x63 p2y1_off6.248.832354
1757x31 p2y1_off14.496712.975344
   
Orange: nodes, hubs and links specific of p2y1_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of p2y1_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner p2y1_on_gp Recurrence p2y1_off Recurrence p2y1_on_gp Hub1? p2y1_off Hub1? p2y1_on_gp Hub2? p2y1_off Hub2? ConSurf1 ConSurf2
17x38 Lig p2y1_on_gp12.56650YesNoYesYes50
23x43 6x45 p2y1_on_gp44.60480YesNoNoNo89
36x45 6x48 p2y1_on_gp46.18883.43718NoNoYesYes98
46x48 6x52 p2y1_on_gp44.37470YesYesYesNo88
56x51 6x52 p2y1_on_gp37.24450NoNoYesNo78
66x51 7x34 p2y1_on_gp36.88520NoNoYesNo74
77x54 8x50 p2y1_on_gp11.9350YesNoNoNo68
82x43 8x50 p2y1_on_gp13.80920NoYesNoNo88
91x57 2x43 p2y1_on_gp14.43330YesYesNoYes68
101x57 I1.W83 p2y1_on_gp15.03830YesYesYesYes66
112x40 I1.W83 p2y1_on_gp20.03616.31664NoNoYesYes76
122x37 2x40 p2y1_on_gp20.65710YesNoNoNo77
132x37 2x39 p2y1_on_gp15.14460YesNoYesYes77
143x43 7x53 p2y1_on_gp50.02750YesNoYesYes89
153x50 7x53 p2y1_on_gp51.54140YesYesYesYes99
163x50 G.H5.25 p2y1_on_gp74.66890YesYesNoNo98
17G.H5.20 G.H5.25 p2y1_on_gp74.79630NoNoNoNo88
186x31 G.H5.20 p2y1_on_gp74.40990YesNoNoNo68
196x31 G.H5.13 p2y1_on_gp75.450YesNoNoNo68
20G.H5.13 G.S6.02 p2y1_on_gp75.80490NoNoYesNo88
21G.H5.10 G.S6.02 p2y1_on_gp76.71370NoNoYesNo78
22G.H5.10 G.S5.03 p2y1_on_gp76.83290NoNoNoNo78
23G.S4.03 G.S5.03 p2y1_on_gp77.49080YesNoNoNo88
24G.S4.03 G.S5.05 p2y1_on_gp89.5980YesNoYesNo89
25G.H1.04 G.S5.05 p2y1_on_gp91.84450YesNoYesNo79
26G.H1.04 G.S4.05 p2y1_on_gp93.09740YesNoNoNo76
27G.S4.05 G.s1h1.05 p2y1_on_gp93.64040NoNoNoNo69
28G.S4.07 G.s1h1.05 p2y1_on_gp93.92020NoNoNoNo89
29G.S4.07 G.s5hg.01 p2y1_on_gp94.47140NoNoYesNo89
30G.s4h3.02 G.s5hg.01 p2y1_on_gp94.65790NoNoYesNo99
31G.HG.07 G.s4h3.02 p2y1_on_gp94.92210NoNoNoNo99
32G.HG.07 G.s4h3.04 p2y1_on_gp94.58730NoNoYesNo98
33G.HG.15 G.s4h3.04 p2y1_on_gp97.70050NoNoYesNo78
34G.HG.15 G.hgh4.02 p2y1_on_gp98.77620NoNoNoNo78
35G.hgh4.02 G.s4h3.15 p2y1_on_gp98.92490NoNoNoNo89
36G.H3.03 G.s4h3.15 p2y1_on_gp98.99870NoNoNoNo49
37G.H3.03 G.H3.06 p2y1_on_gp99.07230NoNoNoNo46
38G.H3.06 G.h4s6.01 p2y1_on_gp99.14550NoNoNoNo64
39G.H3.09 G.h4s6.01 p2y1_on_gp99.00940NoNoNoNo94
40G.H3.09 G.S4.04 p2y1_on_gp1000NoNoYesNo99
41G.H3.12 G.S4.04 p2y1_on_gp38.47910NoNoYesNo89
42G.H3.12 G.H3.15 p2y1_on_gp33.70170NoNoYesNo88
43G.H3.15 G.H3.17 p2y1_on_gp34.09530YesNoYesNo85
44G.H3.17 b.l25x6 p2y1_on_gp20.43560YesNoYesNo58
45b.l23x1 b.l25x6 p2y1_on_gp36.28190YesNoYesNo68
46b.l21x7 b.l23x1 p2y1_on_gp37.07080YesNoYesNo56
47b.l21x7 b.l23x2 p2y1_on_gp26.3410YesNoYesNo58
48b.b24x2 b.l23x2 p2y1_on_gp16.18750NoNoYesNo58
49b.b24x2 b.b25x6 p2y1_on_gp15.80840NoNoNoNo53
50b.b25x5 b.b25x6 p2y1_on_gp15.63110NoNoNoNo43
51b.b24x5 b.b25x5 p2y1_on_gp15.47820NoNoNoNo54
52b.b23x1 b.b24x5 p2y1_on_gp15.46340YesNoNoNo55
53b.b23x1 g.ctx5 p2y1_on_gp10.54970YesNoNoNo59
543x50 G.H5.23 p2y1_on_gp15.75960YesYesYesNo94
55G.H3.17 b.l27x1 p2y1_on_gp12.92490YesNoYesNo59
56b.b26x1 b.l27x1 p2y1_on_gp24.33550NoNoYesNo99
57b.b26x1 b.b26x2 p2y1_on_gp25.26980NoNoNoNo97
58b.b26x2 b.l1x7 p2y1_on_gp23.59420NoNoNoNo79
59b.l1x3 b.l1x7 p2y1_on_gp19.3970YesNoNoNo99
60b.b4x6 b.l1x3 p2y1_on_gp15.07740YesNoYesNo99
61G.S1.07 G.S4.04 p2y1_on_gp13.68390NoNoYesNo99
62G.S1.05 G.S1.07 p2y1_on_gp13.63780NoNoNoNo99
63G.S1.05 G.h2s4.01 p2y1_on_gp14.09790NoNoYesNo99
64G.S2.03 G.S3.04 p2y1_on_gp18.40060NoNoYesNo97
65G.S3.04 b.l5x4 p2y1_on_gp29.51310YesNoNoNo78
66b.b4x1 b.l5x4 p2y1_on_gp28.73810NoNoNoNo88
67b.b4x1 b.l5x1 p2y1_on_gp27.97910NoNoYesNo88
68b.b8x4 b.l5x1 p2y1_on_gp12.00830YesNoYesNo68
69G.h2s4.01 b.l5x5 p2y1_on_gp15.57840YesNoYesNo99
70G.S2.03 b.l5x5 p2y1_on_gp11.42940NoNoYesNo99
71G.S1.03 b.l5x5 p2y1_on_gp11.60730NoNoYesNo99
72G.S1.03 G.S3.04 p2y1_on_gp15.30220NoNoYesNo97
73G.S1.04 G.S3.03 p2y1_on_gp10.43830NoNoYesNo77
74G.S1.04 G.S3.05 p2y1_on_gp10.72910NoNoYesNo77
75G.H3.08 G.S4.04 p2y1_on_gp48.81290NoNoYesNo89
76G.H2.04 G.H3.08 p2y1_on_gp48.77860NoNoNoNo98
77G.H2.04 G.H2.07 p2y1_on_gp48.80620NoNoYesNo99
78G.H2.07 b.l9x6 p2y1_on_gp64.97860YesNoYesNo98
79G.H2.06 b.l9x6 p2y1_on_gp76.33810YesNoYesNo98
80b.b14x1 b.l9x6 p2y1_on_gp11.59980NoNoYesNo88
81G.H2.06 b.l19x1 p2y1_on_gp78.93920YesNoYesNo99
82b.b2x1 b.l27x1 p2y1_on_gp29.07660YesNoYesNo89
83b.b6x1 b.l9x6 p2y1_on_gp33.74490NoNoYesNo98
84G.H2.10 b.b6x1 p2y1_on_gp29.05960NoNoNoNo79
85G.H2.10 b.b2x1 p2y1_on_gp28.34240NoNoYesNo78
86b.l17x5 b.l19x1 p2y1_on_gp79.31870NoNoYesNo69
87b.l17x5 b.l19x2 p2y1_on_gp79.16640NoNoYesNo69
88b.l17x4 b.l19x2 p2y1_on_gp22.81730NoNoYesNo39
89b.l17x3 b.l17x4 p2y1_on_gp22.6230YesNoNoNo93
90b.b19x4 b.l17x3 p2y1_on_gp35.540YesNoYesNo89
91b.b19x4 b.b20x6 p2y1_on_gp28.57260YesNoYesNo86
92b.b17x7 b.b20x6 p2y1_on_gp63.71910YesNoYesNo86
93b.b17x5 b.b17x7 p2y1_on_gp60.83250YesNoYesNo78
94b.b17x5 b.b21x1 p2y1_on_gp49.0040YesNoNoNo77
95b.1x19 b.b21x1 p2y1_on_gp46.03890NoNoNoNo67
96b.1x15 b.1x19 p2y1_on_gp44.56320NoNoNoNo76
97b.1x14 b.1x15 p2y1_on_gp41.6010NoNoNoNo47
98b.1x11 b.1x14 p2y1_on_gp38.63770NoNoNoNo84
99b.1x11 g.h1x12 p2y1_on_gp28.2560NoNoNoNo86
100g.h1x12 g.h1x8 p2y1_on_gp26.77160NoNoNoNo67
101b.1x4 g.h1x8 p2y1_on_gp23.8020NoNoNoNo87
102b.b19x6 b.l19x2 p2y1_on_gp22.81690NoNoYesNo99
103b.b19x6 b.l17x3 p2y1_on_gp22.62230NoNoYesNo99
104b.b20x2 b.l19x2 p2y1_on_gp33.38050YesNoYesNo69
105b.b20x2 b.l17x3 p2y1_on_gp22.62560YesNoYesNo69
106b.b20x4 b.l17x3 p2y1_on_gp30.46240YesNoYesNo89
107b.b20x4 b.b20x6 p2y1_on_gp38.10510YesNoYesNo86
108b.b20x2 b.b21x6 p2y1_on_gp10.3610YesNoNoNo61
109b.b20x4 b.b21x6 p2y1_on_gp10.16730YesNoNoNo81
110b.1x4 g.h1x4 p2y1_on_gp13.39840NoNoNoNo85
111b.1x1 g.h1x4 p2y1_on_gp11.91090NoNoNoNo45
112b.l21x5 b.l21x7 p2y1_on_gp10.59590YesNoYesNo45
113b.b23x6 b.l21x5 p2y1_on_gp10.20440YesNoYesNo74
114b.b23x6 b.b24x6 p2y1_on_gp18.93990YesNoYesNo78
115b.b21x7 b.b24x6 p2y1_on_gp16.65350YesNoYesNo58
116b.b21x7 b.b23x2 p2y1_on_gp12.94770YesNoYesNo56
117b.b22x5 b.b23x2 p2y1_on_gp11.53930NoNoYesNo76
118b.b23x6 b.l23x2 p2y1_on_gp10.37540YesNoYesNo78
119b.b3x2 b.b4x6 p2y1_on_gp11.03740NoNoYesNo59
120b.b2x5 b.b3x2 p2y1_on_gp10.85430YesNoNoNo75
121b.b7x4 b.l5x1 p2y1_on_gp14.48090NoNoYesNo88
122b.b4x3 b.b7x4 p2y1_on_gp13.7760NoNoNoNo78
123b.b3x3 b.b4x3 p2y1_on_gp13.00450YesNoNoNo87
124b.b6x1 b.l7x1 p2y1_on_gp11.56790NoNoNoNo99
125b.b7x5 b.l7x1 p2y1_on_gp11.33430NoNoNoNo99
126b.b7x5 b.l9x7 p2y1_on_gp11.10030NoNoNoNo97
127b.b10x1 b.b14x1 p2y1_on_gp14.83410NoNoNoNo98
128b.b10x1 b.b11x5 p2y1_on_gp14.58260NoNoYesNo96
129G.S3.05 G.S4.03 p2y1_on_gp11.37950YesNoYesNo78
130b.l25x6 b.l27x1 p2y1_on_gp16.20690YesNoYesNo89
131G.H2.07 G.h2s4.01 p2y1_on_gp10.64760YesNoYesNo99
1327x34 7x38 Shared30.353526.9164YesNoYesNo45
1337x23 7x27 p2y1_off012.2104NoNoNoNo42
1347x26 7x27 p2y1_off014.3635NoNoNoNo12
1357x26 7x30 p2y1_off1.2173715.4323NoNoNoNo14
1366x58 7x30 p2y1_off1.4599417.5543NoNoNoNo44
137E1.T115 E2.R195 p2y1_off010.2934NoYesYesYes41
138E2.R195 Lig p2y1_off1.9215911.274YesYesYesYes10
1391x35 2x64 p2y1_off0.17996817.6762YesNoYesNo65
1402x63 2x64 p2y1_off6.4464716.7501YesNoYesNo55
1412x63 E1.T115 p2y1_off0.46181520.0809YesNoNoYes54
1426x58 7x34 p2y1_off3.0945211.9484NoNoYesNo44
1431x35 1x39 p2y1_off0.14663519.0848YesNoYesYes67
1441x39 2x57 p2y1_off4.2142310.9964YesYesYesYes77
1452x60 3x28 p2y1_off014.4855NoNoYesNo74
1463x28 E1x50 p2y1_off2.3112613.1832YesNoYesYes48
1472x53 7x42 p2y1_off041.5757YesYesNoNo77
1482x53 3x32 p2y1_off0.30062666.064YesYesNoYes77
1493x32 3x33 p2y1_off0.38638464.7643NoYesNoNo75
1503x33 E2x52 p2y1_off0.66744837.1034NoNoYesNo56
1517x38 E2x52 p2y1_off3.1089231.8426YesNoYesNo56
1521x57 2x44 p2y1_off0.012050122.7918YesYesNoYes65
1531x57 7x53 p2y1_off029.7076YesYesYesYes69
1547x49 7x53 p2y1_off088.2669NoNoYesYes99
1552x50 7x49 p2y1_off0100NoYesNoNo99
1562x50 3x35 p2y1_off051.4747NoYesNoNo98
1572x53 3x35 p2y1_off2.5100151.6563YesYesNoNo78
1582x50 7x46 p2y1_off051.1531NoYesNoNo99
1592x53 7x46 p2y1_off051.2439YesYesNoNo79
1601x58 2x44 p2y1_off010.5113NoNoNoYes35
1612x39 2x43 p2y1_off041.5186YesYesNoYes78
1622x43 7x53 p2y1_off062.1806NoYesYesYes89
1632x39 3x49 p2y1_off0.14882620.5142YesYesYesNo78
1642x39 3x50 p2y1_off022.5687YesYesYesYes79
1652x41 4x42 p2y1_off011.3596NoNoNoNo68
1662x42 4x42 p2y1_off0.2508612.4672YesYesNoNo78
1672x42 3x46 p2y1_off1.3073515.754YesYesYesNo78
1682x43 3x46 p2y1_off016.7449NoYesYesNo88
1692x41 4x46 p2y1_off010.2467NoNoNoNo67
1703x37 5x43 p2y1_off021.2846NoYesNoNo75
1715x39 5x43 p2y1_off0.48137622.1925YesYesNoNo55
1724x63 5x39 p2y1_off1.150712.3765NoYesYesYes45
1733x33 4x60 p2y1_off0.228.2316NoNoNoNo54
1743x40 6x48 p2y1_off1.2200313.3959NoNoYesYes78
1756x48 7x45 p2y1_off019.8552YesYesNoNo89
1767x45 7x49 p2y1_off1.2660420.9136NoNoNoNo99
1773x40 5x50 p2y1_off012.3012NoNoNoNo79
1783x49 I2x57 p2y1_off0.35618118.3533YesNoNoNo88
1793x50 6x30 p2y1_off016.2313YesYesNoNo94
1803x51 3x52 p2y1_off012.8745YesYesNoYes75
1813x52 I2x57 p2y1_off0.021283217.243NoYesNoNo58
1823x54 6x30 p2y1_off015.1859NoNoNoNo84
1833x54 5x65 p2y1_off012.0081NoNoNoNo88
1841x39 7x42 p2y1_off1.7646340.9271YesYesNoNo77
1857x34 Lig p2y1_off014.4906YesNoYesYes40
1864x60 5x39 p2y1_off1.2672929.1707NoNoYesYes45
1871x39 2x60 p2y1_off014.8901YesYesNoNo77

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
E3.Q291NT.C42Shared6.13.050012
7x31NT.L44p2y1_off18.7601011
LigNT.L44p2y1_off19.8901201
7x28NT.T45p2y1_off8.6700021
1x32NT.K46p2y1_off7.4401021
E1.T115NT.K46p2y1_off9.0101021
LigNT.K46p2y1_off5.2901201
1x317x31p2y1_off10.1501021
1x317x35Shared17.927.681022
1x32E1.T115Shared5.193.891022
1x351x39Shared14.075.860022
1x352x64Shared8.213.520021
1x362x64p2y1_off5.5600021
1x392x60p2y1_off9.3800022
2x632x64Shared9.9314.890211
2x63E1.T115Shared8.744.990212
2x63E1x50Shared10.6111.580212
E1.T115E2.R195p2y1_off5.1701021
E1x50E2x50Shared14.3713.062222
3x294x64p2y1_off5.2700212
3x29E2x50Shared11.149.750212
3x29E2x52Shared17.8713.10211
3x33E2x52Shared6.33.780021
E2.N197E2.R195Shared4.827.231021
E2.R195E2.T199p2y1_off9.0601212
E2.R195E2.T201Shared10.359.061211
E2.R195LigShared8.3511.321210
E2.N197E2.T199Shared13.1614.621022
E2.T201E2x51Shared4.9919.970211
E2.S207E2x51Shared6.361.270021
7x38E2x52Shared9.533.570211
5x36E2.T205Shared9.9911.241221
6x62E2.T205p2y1_off6.4701011
E2.T205LigShared6.4510.071210
5x36E2.T206Shared6.2411.241222
5x336x62Shared14.583.640021
5x366x55p2y1_off4.7801222
6x587x30Shared4.434.431012
6x587x34Shared17.448.141011
6x58Ligp2y1_off13.7301010
6x62LigShared24.2910.561010
7x317x35Shared11.2719.161012
7x31LigShared11.7210.921010
7x347x38Shared12.3514.41211
7x34Ligp2y1_off4.401210
7x357x38Shared9.358.181221
E2.G193E2x51Shared4.352.90021
E3.Q291Ligp2y1_off3.3300010
7x28NT.L44p2y1_off1.3600021
E3.Q291NT.K41p2y1_on_gp09.490012
7x28NT.K46p2y1_on_gp012.440021
1x322x64p2y1_on_gp04.131021
1x327x31p2y1_on_gp013.411021
1x351x36p2y1_on_gp03.280022
1x357x35p2y1_on_gp03.990022
1x397x38p2y1_on_gp03.090021
2x603x29p2y1_on_gp09.720021
2x633x29p2y1_on_gp03.090211
2x63E2x50p2y1_on_gp06.720212
2x63Ligp2y1_on_gp08.740210
2x643x29p2y1_on_gp03.090211
2x647x38p2y1_on_gp06.170211
2x64Ligp2y1_on_gp08.010210
E1.T115E2.T201p2y1_on_gp04.711021
3x29Ligp2y1_on_gp04.530210
E2.K196E2.R195p2y1_on_gp017.330021
E2.R195E2x51p2y1_on_gp09.261211
E2.T201Ligp2y1_on_gp03.660210
E2x51Ligp2y1_on_gp010.190210
E2.T205E2x52p2y1_on_gp010.121211
E2x52Ligp2y1_on_gp014.330210
E2.T205E2.T206p2y1_on_gp04.711212
5x33E2.T206p2y1_on_gp04.420022
6x517x34p2y1_on_gp04.137021
6x557x34p2y1_on_gp08.360221
6x586x62p2y1_on_gp09.641011
6x62E3.Q291p2y1_on_gp010.511011
7x347x35p2y1_on_gp05.641212
7x347x37p2y1_on_gp03.751212
7x38Ligp2y1_on_gp03.020210
LigNT.T45p2y1_on_gp02.751201

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
p2y1_on_gp 7XXH-P2Y1-2MeSADP-chim(NtGi1-G11)/β1/γ2
p2y1_off 4XNW-P2Y1-MRS2500
Network Difference
Value p2y1_on_gp p2y1_off
Imin 3 4.35
Number of Linked Nodes 872 271
Number of Specific Nodes 610 (69.95%) 9  (3.32%)
Number of Shared Nodes 262 (30.05%) 262  (96.68%)
Number of Links 1066 293
Number of Specific Links 919 (86.21%) 146  (49.83%)
Number of Shared Links 147 (13.79%) 147  (50.17%)
Number of Hubs 164 30
Number of Specific Hubs 145 (88.41%) 11  (36.67%)
Number of Shared Hubs 19 (11.59%) 19  (63.33%)
Average % Shared Neighbours (Jaccard) 10.69
Average % Shared Neighbours (Otsuka) 13.61
Average % Shared Neighbours (Overlap Coefficient) 16.31
Average % Shared Cliques (k3-6) 50.68
Graphlets Similarity 0.564068
Paths Difference
Value p2y1_on_gp p2y1_off
Number Of Nodes in MetaPath 125 55
Specific Nodes in MetaPath 116 (92.80%) 46  (83.64%)
Shared Nodes in MetaPath 262 (30.05%) 262  (30.05%)
Number Of Links MetaPath 132 56
Specific Links in MetaPath 131 (99.24%) 55  (98.21%)
Shared Links in MetaPath 147 (13.79%) 147  (13.79%)
Number of Shortest Paths 1204954 60102
Length Of Smallest Path 3 3
Average Path Length 34.4233 14.6999
Length of Longest Path 70 32
Minimum Path Strength 1.355 1.555
Average Path Strength 6.6243 7.18433
Maximum Path Strength 21.405 22.09
Minimum Path Correlation 0.7 0.7
Average Path Correlation 0.983202 0.922578
Maximum Path Correlation 1 0.99
Minimum % Of Corr. Nodes 1.96078 4.7619
Average % Of Corr. Nodes 44.466 48.5445
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 46.1575 39.1574
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

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