Orange: nodes, hubs and links specific of protein_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of protein_off network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.


Index Hub Owner protein_on_gp Avg Int. Strength protein_off Avg Int. Strength protein_on_gp Num Of Links protein_off Num Of Links ConSurf
1G.HN.11 protein_on_gp00603
2G.HN.37 protein_on_gp00402
3G.HN.52 protein_on_gp00404
4G.S1.02 protein_on_gp1000404
5G.S1.03 protein_on_gp00409
6G.S1.05 protein_on_gp00409
7G.S1.06 protein_on_gp100408
8G.S2.08 protein_on_gp89.58330405
9G.S3.01 protein_on_gp500404
10G.S3.03 protein_on_gp950507
11G.S3.04 protein_on_gp86.8750406
12G.S3.05 protein_on_gp00506
13G.S3.06 protein_on_gp1000506
14G.S3.07 protein_on_gp00409
15G.s3h2.03 protein_on_gp83.750509
16G.H2.04 protein_on_gp00409
17G.H2.06 protein_on_gp1000709
18G.H2.07 protein_on_gp1000609
19G.h2s4.01 protein_on_gp98.33330409
20G.s4h3.02 protein_on_gp00409
21G.s4h3.03 protein_on_gp00408
22G.s4h3.04 protein_on_gp83.750708
23G.H3.09 protein_on_gp1000609
24G.H3.17 protein_on_gp86.250604
25G.H3.18 protein_on_gp83.1250409
26G.S5.04 protein_on_gp38.1250409
27G.S5.05 protein_on_gp93.54170709
28G.S5.06 protein_on_gp00408
29G.HG.04 protein_on_gp76.250508
30G.hgh4.02 protein_on_gp43.750808
31G.hgh4.05 protein_on_gp71.8750406
32G.H4.03 protein_on_gp700403
33G.H4.12 protein_on_gp00405
34G.H4.15 protein_on_gp32.08330408
35G.h4s6.02 protein_on_gp69.3750407
36G.h4s6.11 protein_on_gp00408
37G.S6.02 protein_on_gp23.33330408
38G.s6h5.01 protein_on_gp68.750409
39G.H5.08 protein_on_gp88.750408
40G.H5.26 protein_on_gp13.33330405
41b.1x4 protein_on_gp00408
42b.h2x1 protein_on_gp00405
43b.lhb1x6 protein_on_gp00403
44b.lhb1x9 protein_on_gp00403
45b.b1x4 protein_on_gp00407
46b.b1x6 protein_on_gp68.750409
47b.l1x3 protein_on_gp1000609
48b.b2x1 protein_on_gp950508
49b.b2x5 protein_on_gp1000507
50b.b3x3 protein_on_gp500408
51b.l3x2 protein_on_gp77.29170509
52b.b4x2 protein_on_gp50408
53b.b4x3 protein_on_gp75.83330407
54b.b4x4 protein_on_gp500408
55b.b4x5 protein_on_gp81.250407
56b.b4x6 protein_on_gp1000709
57b.b5x2 protein_on_gp00407
58b.b5x3 protein_on_gp1000609
59b.b5x5 protein_on_gp38.750405
60b.b5x7 protein_on_gp400407
61b.l5x1 protein_on_gp84.58330508
62b.l5x5 protein_on_gp93.750709
63b.b6x5 protein_on_gp950806
64b.l6x5 protein_on_gp27.08330404
65b.b7x1 protein_on_gp500504
66b.l7x2 protein_on_gp90.6250409
67b.l7x4 protein_on_gp7.50409
68b.b8x3 protein_on_gp00406
69b.b8x4 protein_on_gp1000406
70b.l8x1 protein_on_gp25.83330405
71b.l8x3 protein_on_gp00403
72b.l9x3 protein_on_gp950509
73b.l9x6 protein_on_gp1000808
74b.b10x5 protein_on_gp88.750609
75b.b11x2 protein_on_gp00407
76b.l11x2 protein_on_gp86.250409
77b.b12x3 protein_on_gp20.83330408
78b.b12x6 protein_on_gp1000708
79b.b12x7 protein_on_gp500409
80b.b13x7 protein_on_gp98.33330507
81b.l13x3 protein_on_gp1000509
82b.l13x6 protein_on_gp91.250409
83b.l13x7 protein_on_gp12.50409
84b.b14x3 protein_on_gp500405
85b.b15x1 protein_on_gp82.50509
86b.b15x3 protein_on_gp350409
87b.l15x2 protein_on_gp33.750409
88b.b16x4 protein_on_gp950506
89b.b16x5 protein_on_gp27.91670405
90b.b16x6 protein_on_gp1000508
91b.b17x5 protein_on_gp500407
92b.b17x7 protein_on_gp91.8750408
93b.l17x3 protein_on_gp1000709
94b.l17x6 protein_on_gp88.750509
95b.b18x3 protein_on_gp43.33330408
96b.b18x5 protein_on_gp00405
97b.l18x1 protein_on_gp1000806
98b.l18x3 protein_on_gp00405
99b.b19x2 protein_on_gp1000506
100b.b19x4 protein_on_gp40.20830408
101b.l19x2 protein_on_gp700509
102b.b20x2 protein_on_gp68.750406
103b.b20x4 protein_on_gp1000508
104b.b20x6 protein_on_gp1000506
105b.b20x7 protein_on_gp00409
106b.l20x2 protein_on_gp00509
107b.b21x1 protein_on_gp850507
108b.b21x2 protein_on_gp00406
109b.b21x5 protein_on_gp00404
110b.b21x7 protein_on_gp91.250605
111b.l22x5 protein_on_gp48.33330509
112b.b23x1 protein_on_gp500405
113b.b23x6 protein_on_gp1000707
114b.l23x1 protein_on_gp50406
115b.b24x4 protein_on_gp39.16670406
116b.b24x6 protein_on_gp500408
117b.l24x2 protein_on_gp00406
118b.l24x3 protein_on_gp00405
119b.l25x3 protein_on_gp1000509
120b.l25x4 protein_on_gp00405
121b.l25x6 protein_on_gp500408
122b.b27x1 protein_on_gp00406
123b.l27x1 protein_on_gp1000709
124b.l27x2 protein_on_gp85.83330409
125b.b28x3 protein_on_gp58.33330407
126b.b28x4 protein_on_gp97.50406
127b.b28x6 protein_on_gp1000509
128g.h1x8 protein_on_gp00407
129g.h1x11 protein_on_gp00409
130g.l1x4 protein_on_gp00508
131g.h2x11 protein_on_gp87.08330406
132g.ctx3 protein_on_gp450409
133g.ctx4 protein_on_gp00407
134g.ctx6 protein_on_gp500606
135g.ctx15 protein_on_gp82.08330409
136g.ctx16 protein_on_gp950708
1371x59 protein_on_gp00434
1382x46 protein_on_gp600429
1393x33 protein_on_gp12.50425
1403x54 protein_on_gp00428
1414x54 protein_on_gp00424
1425x50 protein_on_gp00439
1435x64 protein_on_gp00415
1446x59 protein_on_gp00425
1457x26 protein_on_gp00431
1467x49 protein_on_gp80.6250639
1477x55 protein_on_gp00426
1488x50 protein_on_gp450418
149G.H1.08 protein_on_gp500400
150I2x57 protein_on_gp500420
151g.ntx4 protein_on_gp00400
152I1 protein_on_gp500410
153Lig Shared10010024150
154NT Shared41.875504123
1551x35 Shared00465
1561x39 Shared88.7533.3333448
1572x42 Shared1000657
1582x50 Shared59.166750549
1592x53 Shared82.562.5556
160E1x50 Shared100100678
161E1x52 Shared70.83330547
1623x50 Shared9550569
163E2 Shared10010015134
1645x58 Shared10050659
1656x44 Shared77.550449
1666x48 Shared100100569
1676x51 Shared87.083350547
168E3 Shared25.62562.55104
1697x42 Shared10037.5547
1707x53 Shared10050699
1711x43 protein_off00346
1721x50 protein_off00249
1731x53 protein_off050248
1741x60 protein_off00375
1752x38 protein_off150246
1762x40 protein_off00348
1772x62 protein_off00144
1783x37 protein_off42.587.5367
1793x42 protein_off200347
1803x49 protein_off77.550358
1813x51 protein_off21.87520.8333348
1824x50 protein_off12.50269
1834x65 protein_off5050345
1845x35 protein_off00342
1855x47 protein_off00348
1865x60 protein_off00244
1877x35 protein_off050145
1887x45 protein_off2050359
1897x56 protein_off00347
1908x54 protein_off00246
   
Orange: nodes, hubs and links specific of protein_on_gp network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of protein_off network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.


Index Node1 Node2 Owner protein_on_gp Recurrence protein_off Recurrence protein_on_gp Hub1? protein_off Hub1? protein_on_gp Hub2? protein_off Hub2? ConSurf1 ConSurf2
1b.l2x3 b.l2x5 protein_on_gp20.33190NoNoNoNo85
2b.b3x1 b.l2x3 protein_on_gp20.26190NoNoNoNo58
3b.b3x1 b.b6x5 protein_on_gp20.25190NoNoYesNo56
4b.b3x2 b.b4x6 protein_on_gp83.7430NoNoYesNo59
5b.b2x5 b.b3x2 protein_on_gp83.81890YesNoNoNo75
6b.b2x3 b.b2x5 protein_on_gp96.91840NoNoYesNo67
7b.b26x2 b.b2x3 protein_on_gp96.97410NoNoNoNo76
8b.b26x1 b.b26x2 protein_on_gp97.0050NoNoNoNo97
9b.b26x1 b.l27x1 protein_on_gp97.03890NoNoYesNo99
10b.b2x1 b.l27x1 protein_on_gp55.67550YesNoYesNo89
11b.b2x1 b.l3x1 protein_on_gp55.69090YesNoNoNo89
12b.l3x1 b.l5x5 protein_on_gp55.79620NoNoYesNo99
13b.l1x3 b.l3x2 protein_on_gp86.82370YesNoYesNo99
14b.l1x4 b.l3x2 protein_on_gp1000NoNoYesNo69
15I1 b.l1x4 protein_on_gp99.7450YesNoNoNo06
168x48 I1 protein_on_gp97.01310NoNoYesNo50
177x56 8x48 protein_on_gp96.89890NoYesNoNo75
187x56 8x47 protein_on_gp96.63881.61226NoYesNoNo78
198x47 8x50 protein_on_gp96.50850NoNoYesNo88
207x54 8x50 protein_on_gp94.68220NoNoYesNo68
212x43 7x54 protein_on_gp94.28090NoNoNoNo86
222x43 7x53 protein_on_gp94.14671.99903NoNoYesYes89
233x46 7x53 protein_on_gp39.53540NoNoYesYes99
242x42 3x46 protein_on_gp40.63620.731507YesYesNoNo79
252x42 3x49 protein_on_gp19.43944.51096YesYesNoYes78
263x49 I2x57 protein_on_gp19.0150.924894NoYesYesNo80
273x53 I2x57 protein_on_gp37.61430NoNoYesNo80
283x53 G.H5.19 protein_on_gp36.7640NoNoNoNo88
29G.H5.15 G.H5.19 protein_on_gp36.33850NoNoNoNo88
30G.H5.11 G.H5.15 protein_on_gp35.48680NoNoNoNo88
31b.b4x6 b.l1x3 protein_on_gp85.42310YesNoYesNo99
322x38 2x42 protein_on_gp19.22250.0735711NoYesYesYes67
332x38 I2x57 protein_on_gp19.01510NoYesYesNo60
34G.H5.11 G.S3.03 protein_on_gp29.84210NoNoYesNo87
35G.S1.04 G.S3.03 protein_on_gp17.40470NoNoYesNo77
36G.S1.04 G.S4.03 protein_on_gp11.84530NoNoNoNo77
37G.h2s4.01 b.l5x5 protein_on_gp18.17810YesNoYesNo99
38G.H3.17 b.l27x1 protein_on_gp34.75570YesNoYesNo49
39G.H3.15 G.H3.17 protein_on_gp42.41220NoNoYesNo84
40G.S4.03 G.S5.05 protein_on_gp11.40930NoNoYesNo79
41b.l5x5 b.l7x2 protein_on_gp36.31140YesNoYesNo99
42G.s3h2.03 b.l7x2 protein_on_gp18.53480YesNoYesNo99
433x50 7x53 protein_on_gp11.02870YesYesYesYes99
443x50 5x58 protein_on_gp10.4280YesYesYesYes99
453x47 5x57 protein_on_gp14.61470NoNoNoNo97
463x51 5x57 protein_on_gp13.77796.24514NoYesNoNo87
473x51 3x55 protein_on_gp12.10190.739915NoYesNoNo87
486x40 7x53 protein_on_gp10.40720NoNoYesYes79
49G.H2.04 G.H2.07 protein_on_gp26.5220YesNoYesNo99
50G.H2.04 G.H2.08 protein_on_gp41.63580YesNoNoNo98
51G.H2.08 G.H3.15 protein_on_gp41.59290NoNoNoNo88
52G.H2.07 b.l7x2 protein_on_gp17.79320YesNoYesNo99
53G.H2.07 G.h2s4.01 protein_on_gp18.66940YesNoYesNo99
54G.H2.07 b.l9x6 protein_on_gp60.68050YesNoYesNo98
55G.s3h2.03 b.l9x6 protein_on_gp17.63150YesNoYesNo98
56G.H2.06 b.l9x6 protein_on_gp57.59370YesNoYesNo98
57G.H2.04 G.H3.08 protein_on_gp24.90990YesNoNoNo99
58G.H2.06 b.l17x6 protein_on_gp55.23820YesNoYesNo99
59G.H3.08 G.S4.04 protein_on_gp24.79650NoNoNoNo99
60G.H3.09 G.S4.04 protein_on_gp24.68070YesNoNoNo99
61G.H3.06 G.hgh4.02 protein_on_gp14.71930NoNoYesNo78
62b.b2x4 b.b6x5 protein_on_gp32.29320NoNoYesNo66
63b.b10x4 b.b2x4 protein_on_gp32.02910NoNoNoNo66
64b.b10x2 b.b10x4 protein_on_gp31.76640NoNoNoNo66
65b.b10x2 b.b14x3 protein_on_gp31.50360NoNoYesNo65
66b.b14x3 b.b15x1 protein_on_gp27.95090YesNoYesNo59
67b.b15x1 b.b16x6 protein_on_gp22.46590YesNoYesNo98
68b.b16x4 b.b16x6 protein_on_gp11.19650YesNoYesNo68
69b.b16x4 b.b17x6 protein_on_gp10.68880YesNoNoNo67
70b.b17x6 g.h1x14 protein_on_gp10.41330NoNoNoNo79
71g.h1x11 g.h1x14 protein_on_gp20.21240YesNoNoNo99
72b.1x11 g.h1x11 protein_on_gp18.54930NoNoYesNo89
73b.1x11 g.h1x12 protein_on_gp14.1050NoNoNoNo86
74g.h1x12 g.h1x8 protein_on_gp11.32030NoNoYesNo67
75b.b16x6 b.b17x3 protein_on_gp10.9020YesNoNoNo85
76b.b17x3 g.h1x10 protein_on_gp10.62890NoNoNoNo59
77g.h1x10 g.h1x14 protein_on_gp10.35310NoNoNoNo99
78b.l17x5 b.l17x6 protein_on_gp54.55540NoNoYesNo69
79b.l17x5 b.l19x2 protein_on_gp54.19440NoNoYesNo69
80b.l17x3 b.l19x2 protein_on_gp36.55340YesNoYesNo99
81b.b19x4 b.l17x3 protein_on_gp19.30660YesNoYesNo89
82b.b19x4 b.b20x6 protein_on_gp14.45660YesNoYesNo86
83b.b17x7 b.b20x6 protein_on_gp39.70960YesNoYesNo86
84b.b17x7 b.b21x1 protein_on_gp19.19840YesNoYesNo87
85b.b20x4 b.l17x3 protein_on_gp15.65980YesNoYesNo89
86b.b20x4 b.b20x6 protein_on_gp28.89470YesNoYesNo86
87b.b20x2 b.l19x2 protein_on_gp16.45570YesNoYesNo69
88b.b20x2 b.b20x4 protein_on_gp15.65580YesNoYesNo68
89b.l2x5 b.l4x2 protein_on_gp20.74910NoNoNoNo54
90b.l26x5 g.ctx15 protein_on_gp11.20010NoNoYesNo59
91b.l26x5 g.ctx4 protein_on_gp18.4710NoNoYesNo57
92g.ctx3 g.ctx4 protein_on_gp16.87430YesNoYesNo97
93g.ctx3 g.ctx6 protein_on_gp12.65640YesNoYesNo96
94b.l4x2 g.ctx16 protein_on_gp16.14110NoNoYesNo48
95b.b2x5 b.l4x1 protein_on_gp17.49060YesNoNoNo75
96b.l4x1 g.ctx16 protein_on_gp17.3350NoNoYesNo58
97b.b4x2 b.b5x8 protein_on_gp23.17030YesNoNoNo85
98b.b5x7 b.b5x8 protein_on_gp22.84650YesNoNoNo75
99b.l11x1 b.l9x6 protein_on_gp19.02380NoNoYesNo98
100b.b11x6 b.l11x1 protein_on_gp18.63420NoNoNoNo99
101b.b11x6 b.l9x3 protein_on_gp15.73960NoNoYesNo99
102b.b12x6 b.l9x3 protein_on_gp14.52680YesNoYesNo89
103b.b17x5 b.b17x7 protein_on_gp19.33620YesNoYesNo78
104b.b16x5 b.b17x5 protein_on_gp17.06660YesNoYesNo57
105b.b16x5 b.b17x4 protein_on_gp13.4130YesNoNoNo55
1067x49 7x53 protein_on_gp39.2330YesNoYesYes99
1077x45 7x49 protein_on_gp25.68280NoYesYesNo99
1083x36 6x48 protein_on_gp24.29526.86734NoNoYesYes79
1093x36 Lig protein_on_gp24.03710NoNoYesYes70
110b.b4x2 b.l3x2 protein_on_gp20.27690YesNoYesNo89
1113x47 5x58 Shared14.377423.5196NoNoYesYes99
1126x48 7x45 Shared25.30127.5366YesYesNoYes99
1132x53 7x46 Shared10.511133.2815YesYesNoNo68
1142x50 7x46 Shared11.067874.0126YesYesNoNo98
1152x50 7x49 Shared11.314727.4988YesYesYesNo99
1162x57 7x42 protein_off4.3505131.6125NoNoYesYes87
1171x43 2x57 protein_off3.9107312.7698NoYesNoNo68
1182x54 2x57 protein_off017.2682NoNoNoNo68
1191x46 2x54 protein_off0.25751815.1241NoNoNoNo86
1207x35 Lig protein_off013.041NoYesYesYes50
1216x51 Lig protein_off3.0134780.6718YesYesYesYes70
1226x48 6x51 protein_off0100YesYesYesYes97
1232x53 6x48 protein_off054.4174YesYesYesYes69
1241x50 2x50 protein_off0.2593387.0956NoYesYesYes99
1257x45 7x46 protein_off041.3028NoYesNoNo98
1262x53 3x39 protein_off033.4118YesYesNoNo69
1272x50 3x39 protein_off0.25389433.168YesYesNoNo99
1281x50 7x50 protein_off0.2268241.5236NoYesNoNo99
1291x53 7x50 protein_off040.4536NoYesNoNo89
1301x50 2x47 protein_off042.6839NoYesNoNo99
1311x53 2x47 protein_off0.24174340.544NoYesNoNo89
1321x53 7x53 protein_off071.0886NoYesYesYes89
1331x60 7x53 protein_off027.9276NoYesYesYes59
1341x56 1x60 protein_off011.2438NoNoNoYes75
1356x44 6x48 protein_off1.3388621.0519YesYesYesYes99
1365x54 6x44 protein_off1.8837424.9574NoNoYesYes79
1373x47 5x54 protein_off0.65519924.0809NoNoNoNo97
1385x58 6x37 protein_off2.5670813.9155YesYesNoNo97
1393x50 6x37 protein_off013.4782YesYesNoNo97
1403x49 3x50 protein_off010.0099NoYesYesYes89
1412x46 7x49 protein_off1.9053822.4035YesNoYesNo99
1422x46 3x42 protein_off3.5326621.1191YesNoNoYes97
1433x42 4x50 protein_off014.565NoYesNoYes79
144E2 Lig protein_off7.267224.6526YesYesYesYes40
145E1x50 E2 protein_off2.8160715.3469YesYesYesYes84
1463x36 5x43 protein_off018.2057NoNoNoNo75
1473x37 5x43 protein_off0.95279417.3964NoYesNoNo75
148Lig NT protein_off0.43189621.672YesYesYesYes03
1493x40 6x44 protein_off0.15657813.8713NoNoYesYes79
1503x40 5x50 protein_off1.2693613.2134NoNoYesNo79
1513x44 5x50 protein_off0.5083210.5396NoNoYesNo79
1523x37 5x461 protein_off010.1759NoYesNoNo76
1536x36 7x53 protein_off020.9447NoNoYesYes79
1546x36 7x56 protein_off011.2438NoNoNoYes77
1557x38 7x42 protein_off0.70476317.0096NoNoYesYes67
156E3 NT protein_off012.753YesYesYesYes43
1571x46 7x47 protein_off012.9758NoNoNoNo86
1582x40 7x53 protein_off012.1224NoYesYesYes89
1596x51 7x38 protein_off0.08441817.8925YesYesNoNo76
1607x42 Lig protein_off019.8348YesYesYesYes70
1616x44 7x45 protein_off014.4704YesYesNoYes99
1622x53 3x36 protein_off0.53304912.2086YesYesNoNo67

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Midway



Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Node1Node2OwnerNet1LinkStrengthNet2LinkStrengthComm1Comm2Node1ShellNode2Shell
1x351x39Shared5.226675.548580022
1x397x39Shared4.215833.055170022
1x397x42Shared4.023335.283960021
2x533x36Shared3.776253.408631021
2x536x48protein_off4.022501022
2x562x60protein_off5.0708300021
2x577x42Shared9.469175.624520021
2x603x32Shared7.459173.864191211
2x60LigShared14.31467.744421210
2x63E1x50Shared7.212928.844290222
E1x49E2Shared10.60335.466791021
E1x50E2Shared4.785423.572881221
3x22E2Shared8.42754.514061021
3x32LigShared6.612087.173521210
3x333x37protein_off3.7933300212
3x334x61Shared16.09213.552540211
3x365x43protein_off4.2183301211
3x366x48Shared5.328755.774231212
3x375x43Shared4.065835.352770021
4x615x39protein_off7.9062500212
4x64E2Shared12.622115.17171221
4x645x35Shared4.509583.479791222
4x65E2x52Shared6.386257.16761021
E2E2Shared44.123748.52291211
E2E2x52Shared5.35758.484231211
5x35E2Shared7.405426.480191221
5x36E2Shared6.6220810.7280211
5x406x59Shared6.383756.065561022
5x446x56Shared6.830833.627231012
6x486x51protein_off6.1504201221
6x516x55Shared4.469589.3431212
6x517x38Shared5.389584.280061211
7x35Ligprotein_off6.0183301010
7x387x42Shared5.989583.94761211
7x38LigShared5.665835.497631210
7x42Ligprotein_off4.587501010
E2LigShared13.929624.27651210
6x51LigShared16.22384.734751210
7x34LigShared7.167924.478270210
LigNTShared20.822922.57921201
NTNTShared7.205838.991151211
1x357x35Shared8.35753.489350021
E2E2x51Shared11.11129.897541211
6x61E3Shared6.764585.12940212
7x357x39protein_off7.1387501012
4x614x65Shared5.193753.401120212
6x58E3protein_off8.3637501212
E3E3protein_off5.7604201022
5x44Ligprotein_off5.6101010
6x54Ligprotein_off4.60501010
E3NTprotein_off6.8201021
E2NTprotein_off7.15501211
5x40NTprotein_off4.2501021
6x58NTprotein_off4.8701211
3x32NTprotein_off5.65501211
4x65NTprotein_off5.54501021
2x64E1x50protein_off4.5200022
7x307x33protein_off4.0400212
6x547x37protein_off3.6101012
5x325x35protein_off3.5962500022
1x357x31protein_off3.57500021
7x307x32protein_off3.56500212
7x33E3protein_off2.9801022
E1NTprotein_off2.87500211
1x427x39protein_off2.7700022
6x62E3protein_off2.537501012
1x387x35protein_off2.07500021
7x27LigShared1.800834.254060010
6x626x63protein_off1.6037501012
7x24NTShared1.516672.885460021
1x33NTprotein_off1.4100021
5x31E2protein_off1.117500021
1x28LigShared0.528751.704250210
6x65E3protein_off0.212500022
7x31Ligprotein_on_gp03.207210210
E2x51Ligprotein_on_gp018.39040210
2x533x32protein_on_gp07.843831021
2x537x42protein_on_gp05.421461021
3x334x57protein_on_gp04.529210212
5x39E2protein_on_gp06.314190221
5x32E2protein_on_gp03.583350021
5x406x55protein_on_gp03.364251022
6x516x52protein_on_gp04.94241212
6x517x37protein_on_gp03.425251212
6x547x34protein_on_gp06.504061011
1x427x42protein_on_gp03.13510021
2x602x63protein_on_gp03.297811212
2x63E2protein_on_gp03.741210221
3x33Ligprotein_on_gp04.837670210
5x315x35protein_on_gp04.331870022
5x366x59protein_on_gp03.667250212
5x446x52protein_on_gp05.683421012
6x587x30protein_on_gp04.800211211
6x58Ligprotein_on_gp09.546691210
6x61Ligprotein_on_gp08.10650210
5x43Ligprotein_on_gp05.470810210
E2x52Ligprotein_on_gp04.530751210
3x335x43protein_on_gp03.730250211
5x36Ligprotein_on_gp03.696190210
4x61Ligprotein_on_gp03.331580210
3x36Ligprotein_on_gp03.623121210
7x30Ligprotein_on_gp06.765940210
E1Ligprotein_on_gp04.640210
2x67E2protein_on_gp02.7650221
1x387x39protein_on_gp02.370380022
2x64E1protein_on_gp020021
6x547x33protein_on_gp01.970541012
6x62Ligprotein_on_gp01.742271010
1x247x31protein_on_gp01.298750021
1x251x28protein_on_gp00.3710021
6x657x30protein_on_gp00.36550021

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
Id Description
protein_on_gp chemokine_on_gp
chemerin_on_gp
protein_off chemokine_off
grh_off
Network Difference
Value protein_on_gp protein_off
Imin 3.11613 3.76958
Number of Linked Nodes 949 286
Number of Specific Nodes 666 (70.18%) 3  (1.05%)
Number of Shared Nodes 283 (29.82%) 283  (98.95%)
Number of Links 1127 311
Number of Specific Links 984 (87.31%) 168  (54.02%)
Number of Shared Links 143 (12.69%) 143  (45.98%)
Number of Hubs 170 38
Number of Specific Hubs 152 (89.41%) 20  (52.63%)
Number of Shared Hubs 18 (10.59%) 18  (47.37%)
Average % Shared Neighbours (Jaccard) 9.83
Average % Shared Neighbours (Otsuka) 12.44
Average % Shared Neighbours (Overlap Coefficient) 15.03
Average % Shared Cliques (k3-6) 75.87
Graphlets Similarity 0.572535
Paths Difference
Value protein_on_gp protein_off
Number Of Nodes in MetaPath 111 48
Specific Nodes in MetaPath 97 (87.39%) 34  (70.83%)
Shared Nodes in MetaPath 283 (29.82%) 283  (29.82%)
Number Of Links MetaPath 115 52
Specific Links in MetaPath 110 (95.65%) 47  (90.38%)
Shared Links in MetaPath 143 (12.69%) 143  (12.69%)
Number of Shortest Paths 1610165 78043
Length Of Smallest Path 3 3
Average Path Length 31.3089 13.4645
Length of Longest Path 58 23
Minimum Path Strength 0.139 0.96125
Average Path Strength 5.71479 6.03564
Maximum Path Strength 22.8182 14.399
Minimum Path Correlation 0.701604 0.700417
Average Path Correlation 0.971441 0.898037
Maximum Path Correlation 1 0.98375
Minimum % Of Corr. Nodes 2.08333 4.7619
Average % Of Corr. Nodes 39.4473 37.3169
Maximum % Of Corr. Nodes 100 100
Minimum Path Hubs % 0 0
Average Path Hubs % 49.7618 53.2643
Maximum Path Hubs % 100 100

Details about the values in these tables can be found in the corresponding documentation page .

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Download protein_off_on_gp.zip<



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