psnGPCR

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Orange: nodes, hubs and links specific of tachykinin_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of tachykinin_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	tachykinin_off Int. Strength	tachykinin_on Int. Strength	tachykinin_off Hub1?	tachykinin_on Hub1?	tachykinin_off Hub2?	tachykinin_on Hub2?	ConSurf1	ConSurf2
1	1x50	2x47	tachykinin_off	100	0	Yes	No	No	No	9	9
2	1x53	7x53	tachykinin_off	100	0	No	No	Yes	Yes	8	9
3	1x57	8x50	tachykinin_off	100	0	No	No	Yes	No	7	9
4	1x58	2x44	tachykinin_off	100	0	No	No	No	No	2	6
5	1x60	I1x50	tachykinin_off	100	0	No	No	No	No	5	7
6	I1x48	I1x51	tachykinin_off	100	0	No	No	Yes	No	6	6
7	2x37	2x40	tachykinin_off	100	0	No	No	No	Yes	7	8
8	2x38	3x49	tachykinin_off	100	0	No	Yes	Yes	No	6	9
9	2x39	3x46	tachykinin_off	100	0	No	No	No	No	8	9
10	2x39	3x49	tachykinin_off	100	0	No	No	Yes	No	8	9
11	2x39	3x50	tachykinin_off	100	0	No	No	No	No	8	9
12	2x46	3x43	tachykinin_off	100	0	No	No	No	No	9	8
13	2x48	4x50	tachykinin_off	100	0	Yes	No	Yes	No	6	9
14	2x57	3x31	tachykinin_off	100	0	Yes	Yes	No	Yes	6	4
15	2x67	E1x49	tachykinin_off	100	0	Yes	No	No	No	5	4
16	2x67	E1x51	tachykinin_off	100	0	Yes	No	Yes	No	5	2
17	3x25	E1x50	tachykinin_off	100	0	No	No	Yes	Yes	9	8
18	3x28	E1x50	tachykinin_off	100	0	No	Yes	Yes	Yes	5	8
19	E1x51	E1x52	tachykinin_off	100	0	Yes	No	Yes	Yes	2	7
20	3x28	3x29	tachykinin_off	100	0	No	Yes	Yes	Yes	5	5
21	3x29	E2x52	tachykinin_off	100	0	Yes	Yes	Yes	No	5	4
22	3x30	4x57	tachykinin_off	100	0	No	No	No	No	6	7
23	3x32	Lig	tachykinin_off	100	0	No	No	Yes	Yes	6	0
24	3x33	5x43	tachykinin_off	100	0	Yes	Yes	No	No	5	5
25	3x36	5x461	tachykinin_off	100	0	No	Yes	No	No	7	6
26	3x36	Lig	tachykinin_off	100	0	No	Yes	Yes	Yes	7	0
27	3x37	3x41	tachykinin_off	100	0	No	Yes	No	No	7	5
28	3x37	4x53	tachykinin_off	100	0	No	Yes	No	No	7	8
29	3x41	3x44	tachykinin_off	100	0	No	No	No	No	5	7
30	3x47	5x54	tachykinin_off	100	0	No	No	No	No	9	8
31	3x49	3x50	tachykinin_off	100	0	Yes	No	No	No	9	9
32	3x50	3x53	tachykinin_off	100	0	No	No	No	No	9	8
33	3x51	5x56	tachykinin_off	100	0	Yes	Yes	No	No	8	4
34	3x52	I2	tachykinin_off	100	0	No	No	Yes	Yes	5	6
35	4x56	5x46	tachykinin_off	100	0	No	No	No	No	5	4
36	4x65	E2x52	tachykinin_off	100	0	No	No	Yes	No	5	4
37	5x36	Lig	tachykinin_off	100	0	No	Yes	Yes	Yes	4	0
38	5x40	6x56	tachykinin_off	100	0	Yes	No	No	No	5	5
39	5x40	Lig	tachykinin_off	100	0	Yes	No	Yes	Yes	5	0
40	5x461	6x52	tachykinin_off	100	0	No	No	Yes	Yes	6	7
41	5x461	Lig	tachykinin_off	100	0	No	No	Yes	Yes	6	0
42	5x54	6x41	tachykinin_off	100	0	No	No	No	No	8	8
43	5x58	6x38	tachykinin_off	100	0	No	Yes	No	No	9	5
44	5x65	6x31	tachykinin_off	100	0	No	No	Yes	No	8	5
45	6x32	8x48	tachykinin_off	100	0	No	No	No	Yes	8	4
46	6x36	7x53	tachykinin_off	100	0	No	No	Yes	Yes	8	9
47	6x36	8x47	tachykinin_off	100	0	No	No	No	No	8	8
48	6x39	7x52	tachykinin_off	100	0	No	No	No	No	5	8
49	6x40	7x49	tachykinin_off	100	0	No	No	No	Yes	7	9
50	6x47	7x45	tachykinin_off	100	0	No	No	No	No	8	9
51	6x48	Lig	tachykinin_off	100	0	Yes	Yes	Yes	Yes	8	0
52	6x52	Lig	tachykinin_off	100	0	Yes	Yes	Yes	Yes	7	0
53	6x57	6x58	tachykinin_off	100	0	No	No	No	No	4	4
54	7x39	7x43	tachykinin_off	100	0	Yes	No	No	No	5	5
55	2x57	3x27	tachykinin_off	100	0	Yes	Yes	Yes	No	6	4
56	2x64	E1x51	tachykinin_off	100	0	No	Yes	Yes	No	4	2
57	3x22	E1x52	tachykinin_off	33.3333	0	No	No	Yes	Yes	3	7
58	1x28	NT	tachykinin_off	33.3333	0	No	No	No	Yes	2	4
59	1x56	8x54	tachykinin_off	33.3333	0	No	No	No	No	8	6
60	3x43	6x44	tachykinin_off	66.6667	0	No	No	No	Yes	8	9
61	8x48	8x49	tachykinin_off	33.3333	0	No	Yes	No	No	4	6
62	5x66	6x35	tachykinin_off	33.3333	0	No	No	No	No	4	6
63	6x50	7x40	tachykinin_off	33.3333	0	No	No	No	No	9	7
64	5x61	6x34	tachykinin_off	33.3333	0	No	No	No	No	8	6
65	1x55	1x60	tachykinin_off	33.3333	0	No	No	No	No	4	5
66	2x41	4x39	tachykinin_off	33.3333	0	Yes	Yes	No	No	5	2
67	1x35	7x39	tachykinin_off	33.3333	0	Yes	No	Yes	No	4	5
68	4x56	5x43	tachykinin_off	33.3333	0	No	No	No	No	5	5
69	3x54	3x55	tachykinin_off	0	0	No	No	Yes	Yes	8	7
70	8x49	I1x50	tachykinin_off	33.3333	0	No	No	No	No	6	7
71	2x49	4x50	tachykinin_off	0	0	No	No	Yes	No	8	9
72	4x45	4x49	tachykinin_off	0	0	No	No	No	No	5	7
73	3x48	I2	tachykinin_off	33.3333	0	No	No	Yes	Yes	5	6
74	2x48	2x53	tachykinin_off	33.3333	0	Yes	No	Yes	Yes	6	7
75	2x53	3x31	tachykinin_off	33.3333	0	Yes	Yes	No	Yes	7	4
76	1x34	1x35	tachykinin_off	33.3333	0	No	No	Yes	No	4	4
77	5x40	5x41	tachykinin_off	33.3333	0	Yes	No	No	No	5	5
78	5x31	5x32	tachykinin_off	33.3333	0	No	No	No	No	1	3
79	1x31	7x32	tachykinin_off	33.3333	0	No	Yes	No	No	2	1
80	3x23	3x24	tachykinin_off	33.3333	0	No	No	No	Yes	3	5
81	2x67	7x31	tachykinin_off	33.3333	0	Yes	No	No	Yes	5	4
82	7x33	7x37	tachykinin_off	0	0	No	No	No	No	5	6
83	3x37	4x52	tachykinin_off	0	0	No	Yes	No	No	7	4
84	5x62	5x66	tachykinin_off	0	0	No	No	No	No	5	4
85	6x27	6x31	tachykinin_off	33.3333	0	No	No	Yes	No	2	5
86	5x68	6x27	tachykinin_off	33.3333	0	No	No	No	No	5	2
87	7x29	7x32	tachykinin_off	0	0	No	No	No	No	3	1
88	5x38	5x42	tachykinin_off	0	0	No	No	No	No	4	4
89	1x46	2x55	tachykinin_off	0	0	No	No	No	No	8	4
90	1x47	2x55	tachykinin_off	0	0	No	No	No	No	6	4
91	6x24	6x31	tachykinin_off	0	0	No	No	Yes	No	2	5
92	4x43	4x47	tachykinin_off	0	0	No	No	No	No	2	3
93	1x47	1x51	tachykinin_off	0	0	No	No	No	No	6	4
94	5x59	5x60	tachykinin_off	0	0	No	No	No	No	3	4
95	1x44	1x45	tachykinin_off	0	0	No	No	No	No	4	4
96	7x55	7x56	tachykinin_off	0	0	No	No	No	No	6	7
97	8x53	8x56	tachykinin_off	0	0	No	No	No	No	6	3
98	5x41	5x45	tachykinin_off	0	0	No	No	No	No	5	4
99	7x30	7x33	tachykinin_off	0	0	No	No	No	No	4	5
100	1x41	7x47	tachykinin_off	0	0	No	No	No	No	5	7
101	8x57	8x58	tachykinin_off	0	0	No	No	No	No	4	6
102	4x54	4x55	tachykinin_off	0	0	No	No	No	No	4	4
103	8x51	8x55	tachykinin_off	0	0	No	No	No	No	8	5
104	1x37	1x40	tachykinin_off	0	0	No	No	No	No	5	4
105	7x51	7x55	tachykinin_off	0	0	No	No	No	No	7	6
106	1x32	1x33	tachykinin_off	0	0	No	No	No	No	3	4
107	5x59	5x63	tachykinin_off	0	0	No	No	No	No	3	3
108	8x56	CT	tachykinin_off	0	0	No	No	No	No	3	5
109	1x28	1x31	Shared	100	100	No	No	No	Yes	2	2
110	1x35	7x35	Shared	100	100	Yes	No	No	Yes	4	3
111	1x39	2x62	Shared	100	100	No	Yes	No	Yes	7	6
112	1x39	7x38	Shared	100	100	No	Yes	No	Yes	7	5
113	1x39	7x39	Shared	100	100	No	Yes	Yes	No	7	5
114	1x42	7x39	Shared	100	100	No	No	Yes	No	7	5
115	1x45	7x47	Shared	100	100	No	No	No	No	4	7
116	1x46	7x46	Shared	100	100	No	No	No	No	8	9
117	1x49	7x50	Shared	100	100	No	No	No	No	8	9
118	1x50	2x50	Shared	100	100	Yes	No	Yes	Yes	9	9
119	1x50	2x51	Shared	100	25	Yes	No	No	No	9	7
120	1x50	7x50	Shared	100	100	Yes	No	No	No	9	9
121	1x52	8x54	Shared	100	100	No	No	No	No	6	6
122	1x54	2x48	Shared	100	100	No	No	Yes	No	7	6
123	1x57	2x40	Shared	100	100	No	No	No	Yes	7	8
124	1x57	2x44	Shared	100	100	No	No	No	No	7	6
125	2x41	I1x51	Shared	100	100	Yes	Yes	Yes	No	5	6
126	2x38	4x42	Shared	100	100	No	Yes	No	Yes	6	7
127	2x41	4x42	Shared	100	100	Yes	Yes	No	Yes	5	7
128	2x42	3x45	Shared	100	100	Yes	Yes	No	No	7	7
129	2x42	4x42	Shared	100	100	Yes	Yes	No	Yes	7	7
130	2x42	4x45	Shared	100	100	Yes	Yes	No	No	7	5
131	2x42	4x46	Shared	100	100	Yes	Yes	No	No	7	8
132	2x43	7x53	Shared	100	100	No	No	Yes	Yes	8	9
133	2x45	3x42	Shared	100	100	No	No	No	No	9	8
134	2x45	4x46	Shared	100	100	No	No	No	No	9	8
135	2x45	4x50	Shared	100	100	No	No	Yes	No	9	9
136	2x46	2x50	Shared	100	100	No	No	Yes	Yes	9	9
137	2x48	2x52	Shared	100	100	Yes	No	No	No	6	6
138	2x50	3x39	Shared	100	100	Yes	Yes	No	No	9	9
139	2x50	7x46	Shared	100	100	Yes	Yes	No	No	9	9
140	2x50	7x49	Shared	100	100	Yes	Yes	No	Yes	9	9
141	2x56	3x27	Shared	100	100	No	Yes	Yes	No	5	4
142	2x57	2x61	Shared	100	100	Yes	Yes	No	Yes	6	6
143	2x57	3x32	Shared	100	100	Yes	Yes	No	No	6	6
144	2x58	7x42	Shared	100	100	No	No	No	No	7	7
145	2x60	E1x52	Shared	100	100	No	No	Yes	Yes	5	7
146	2x60	3x24	Shared	100	100	No	No	No	Yes	5	5
147	2x61	3x28	Shared	100	100	No	Yes	No	Yes	6	5
148	2x62	2x66	Shared	100	100	No	Yes	No	No	6	5
149	2x64	E1x50	Shared	100	100	No	Yes	Yes	Yes	4	8
150	2x66	2x67	Shared	100	100	No	No	Yes	No	5	5
151	E1x49	E1x51	Shared	100	100	No	No	Yes	No	4	2
152	E1x50	E1x52	Shared	100	100	Yes	Yes	Yes	Yes	8	7
153	E1x50	E2x50	Shared	100	100	Yes	Yes	No	Yes	8	9
154	3x24	3x27	Shared	100	100	No	Yes	Yes	No	5	4
155	3x25	E2x50	Shared	100	100	No	No	No	Yes	9	9
156	3x27	3x31	Shared	100	100	Yes	No	No	Yes	4	4
157	3x29	4x61	Shared	100	100	Yes	Yes	Yes	Yes	5	6
158	3x29	4x65	Shared	100	100	Yes	Yes	No	No	5	5
159	3x30	4x54	Shared	100	100	No	No	No	No	6	4
160	3x33	4x61	Shared	100	100	Yes	Yes	Yes	Yes	5	6
161	3x33	Lig	Shared	100	100	Yes	Yes	Yes	Yes	5	0
162	3x36	6x48	Shared	100	100	No	Yes	Yes	Yes	7	8
163	3x38	4x50	Shared	100	100	No	No	Yes	No	7	9
164	3x40	5x50	Shared	100	100	No	No	No	No	7	9
165	3x40	6x44	Shared	100	100	No	No	No	Yes	7	9
166	3x41	5x50	Shared	100	50	No	No	No	No	5	9
167	3x44	5x54	Shared	100	50	No	No	No	No	7	8
168	3x47	5x58	Shared	100	100	No	No	No	Yes	9	9
169	3x51	3x55	Shared	100	100	Yes	Yes	Yes	Yes	8	7
170	3x51	3x56	Shared	100	100	Yes	Yes	No	Yes	8	6
171	3x51	5x60	Shared	100	100	Yes	Yes	No	No	8	4
172	3x55	3x56	Shared	100	100	Yes	Yes	No	Yes	7	6
173	3x55	5x64	Shared	100	100	Yes	Yes	No	No	7	5
174	3x56	I2	Shared	100	100	No	Yes	Yes	Yes	6	6
175	I2	I2	Shared	100	100	Yes	Yes	Yes	Yes	6	6
176	4x59	4x60	Shared	100	100	No	No	No	No	4	8
177	4x59	4x63	Shared	100	100	No	No	No	No	4	4
178	4x60	5x39	Shared	100	100	No	No	Yes	Yes	8	6
179	4x61	5x39	Shared	100	100	Yes	Yes	Yes	Yes	6	6
180	4x61	Lig	Shared	100	100	Yes	Yes	Yes	Yes	6	0
181	4x63	4x64	Shared	100	100	No	No	No	No	4	5
182	4x64	E2	Shared	100	100	No	No	Yes	Yes	5	3
183	E2	E2	Shared	100	100	Yes	Yes	Yes	Yes	3	3
184	E2	E2x51	Shared	100	100	Yes	Yes	No	No	3	4
185	E2	E2x52	Shared	100	100	Yes	Yes	Yes	No	3	4
186	5x35	E2	Shared	100	100	No	No	Yes	Yes	4	3
187	5x36	E2	Shared	100	100	No	Yes	Yes	Yes	4	3
188	5x39	E2	Shared	100	100	Yes	Yes	Yes	Yes	6	3
189	5x32	5x34	Shared	100	100	No	No	No	Yes	3	1
190	5x37	6x59	Shared	100	50	No	No	No	No	3	5
191	5x39	5x43	Shared	100	100	Yes	Yes	No	No	6	5
192	5x40	6x59	Shared	100	100	Yes	No	No	No	5	5
193	5x44	6x52	Shared	100	100	No	No	Yes	Yes	6	7
194	5x44	6x56	Shared	100	50	No	No	No	No	6	5
195	5x47	5x48	Shared	100	100	Yes	Yes	No	No	8	4
196	5x47	5x51	Shared	100	100	Yes	Yes	No	No	8	6
197	5x47	6x49	Shared	100	100	Yes	Yes	No	No	8	5
198	5x47	6x52	Shared	100	100	Yes	Yes	Yes	Yes	8	7
199	5x56	5x60	Shared	100	100	No	No	No	No	4	4
200	5x58	6x37	Shared	100	100	No	Yes	No	Yes	9	8
201	5x66	6x31	Shared	100	100	No	No	Yes	No	4	5
202	6x28	6x31	Shared	100	50	No	No	Yes	No	4	5
203	6x36	7x56	Shared	100	50	No	No	No	No	8	7
204	6x40	7x52	Shared	100	50	No	No	No	No	7	8
205	6x43	7x48	Shared	100	100	No	No	No	No	6	5
206	6x44	6x48	Shared	100	100	No	Yes	Yes	Yes	9	8
207	6x48	6x51	Shared	100	100	Yes	Yes	Yes	Yes	8	7
208	6x48	7x41	Shared	100	100	Yes	Yes	No	No	8	7
209	6x48	7x45	Shared	100	100	Yes	Yes	No	No	8	9
210	6x50	7x37	Shared	100	100	No	No	No	No	9	6
211	6x51	6x55	Shared	100	100	Yes	Yes	No	Yes	7	6
212	6x51	7x41	Shared	100	100	Yes	Yes	No	No	7	7
213	6x51	Lig	Shared	100	100	Yes	Yes	Yes	Yes	7	0
214	6x54	6x55	Shared	100	100	No	Yes	No	Yes	4	6
215	6x54	7x34	Shared	100	100	No	Yes	No	Yes	4	5
216	6x55	Lig	Shared	100	100	No	Yes	Yes	Yes	6	0
217	E3	E3	Shared	100	100	Yes	Yes	Yes	Yes	3	3
218	7x34	7x38	Shared	100	100	No	Yes	No	Yes	5	5
219	7x43	7x48	Shared	100	100	No	No	No	No	5	5
220	7x47	7x48	Shared	100	100	No	No	No	No	7	5
221	7x49	7x53	Shared	100	100	No	Yes	Yes	Yes	9	9
222	7x53	8x50	Shared	100	100	Yes	Yes	Yes	No	9	9
223	7x54	8x54	Shared	100	100	No	No	No	No	7	6
224	8x47	8x49	Shared	100	100	No	No	No	No	8	6
225	8x47	8x50	Shared	100	100	No	No	Yes	No	8	9
226	8x48	8x51	Shared	100	100	No	Yes	No	No	4	8
227	1x28	1x30	Shared	100	100	No	No	No	No	2	1
228	1x30	1x31	Shared	100	100	No	No	No	Yes	1	2
229	4x61	E2x52	Shared	100	100	Yes	Yes	Yes	No	6	4
230	1x55	1x59	Shared	33.3333	100	No	No	No	No	4	4
231	2x68	E2	Shared	33.3333	100	No	Yes	Yes	Yes	4	3
232	2x53	3x35	Shared	66.6667	50	Yes	Yes	No	No	7	8
233	2x63	E1x52	Shared	66.6667	100	No	No	Yes	Yes	4	7
234	3x49	I2	Shared	33.3333	100	Yes	No	Yes	Yes	9	6
235	6x47	7x40	Shared	33.3333	100	No	No	No	No	8	7
236	1x58	I1x51	Shared	33.3333	100	No	No	Yes	No	2	6
237	6x61	E3	Shared	66.6667	100	No	No	Yes	Yes	4	3
238	3x54	5x61	Shared	33.3333	100	No	No	No	No	8	8
239	1x56	8x53	Shared	33.3333	50	No	No	No	No	8	6
240	3x30	4x62	Shared	66.6667	100	No	No	No	No	6	5
241	1x38	7x39	Shared	33.3333	100	No	No	Yes	No	4	5
242	4x38	4x41	Shared	33.3333	50	No	No	No	No	7	4
243	5x65	6x30	Shared	33.3333	100	No	No	No	No	8	7
244	6x25	6x28	Shared	33.3333	50	No	No	No	No	3	4
245	5x49	5x50	Shared	33.3333	0	No	No	No	No	5	9
246	3x33	4x57	Shared	33.3333	100	Yes	Yes	No	No	5	7
247	3x51	5x57	Shared	33.3333	100	Yes	Yes	No	No	8	7
248	1x43	2x58	Shared	66.6667	25	No	No	No	No	6	7
249	5x33	5x36	Shared	33.3333	100	No	No	No	Yes	2	4
250	1x48	1x49	Shared	33.3333	100	No	No	No	No	4	8
251	3x26	4x65	Shared	0	100	No	No	No	No	6	5
252	5x65	6x34	Shared	33.3333	100	No	No	No	No	8	6
253	1x56	8x50	Shared	0	50	No	No	Yes	No	8	9
254	2x53	7x42	Shared	66.6667	100	Yes	Yes	No	No	7	7
255	6x49	6x53	Shared	66.6667	100	No	No	No	No	5	6
256	1x43	2x59	Shared	33.3333	25	No	No	No	No	6	8
257	4x38	4x40	Shared	0	100	No	No	No	No	7	4
258	5x51	6x45	Shared	0	100	No	No	No	No	6	5
259	1x32	2x66	Shared	33.3333	100	No	No	No	No	3	5
260	5x31	E2	Shared	33.3333	100	No	No	Yes	Yes	1	3
261	I1x49	I1x51	Shared	33.3333	50	No	No	Yes	No	5	6
262	4x48	4x52	Shared	0	25	No	No	No	No	3	4
263	2x41	4x43	Shared	33.3333	100	Yes	Yes	No	No	5	2
264	1x46	2x54	Shared	33.3333	50	No	No	No	No	8	6
265	6x58	E3	Shared	33.3333	100	No	No	Yes	Yes	4	3
266	3x44	5x53	Shared	0	100	No	No	No	No	7	6
267	6x60	6x61	Shared	33.3333	50	No	No	No	No	5	4
268	3x21	E1x50	Shared	0	0	No	No	Yes	Yes	8	8
269	1x36	2x62	Shared	0	0	No	No	No	Yes	6	6
270	3x34	4x53	Shared	0	50	No	No	No	No	5	8
271	4x41	I2	Shared	33.3333	0	No	No	Yes	Yes	4	6
272	4x51	4x55	Shared	0	0	No	No	No	No	3	4
273	2x65	7x34	Shared	0	100	No	No	No	Yes	5	5
274	1x35	7x36	Shared	0	50	Yes	No	No	No	4	5
275	1x55	8x57	Shared	33.3333	0	No	No	No	No	4	4
276	7x30	E3	Shared	0	100	No	No	Yes	Yes	4	3
277	1x35	7x32	Shared	0	100	Yes	No	No	No	4	1
278	6x38	6x42	Shared	0	0	No	No	No	No	5	4
279	5x34	5x38	Shared	0	0	No	Yes	No	No	1	4
280	6x33	6x37	Shared	0	100	No	No	No	Yes	7	8
281	5x55	5x59	Shared	0	50	No	No	No	No	4	3
282	5x63	5x67	Shared	0	100	No	No	No	No	3	4
283	4x44	4x48	Shared	0	0	No	No	No	No	3	3
284	6x26	6x27	Shared	0	25	No	No	No	No	4	2
285	8x52	8x55	Shared	0	25	No	No	No	No	4	5
286	NT	NT	tachykinin_on	0	100	No	Yes	No	Yes	4	4
287	E2	NT	tachykinin_on	0	100	Yes	Yes	No	Yes	3	4
288	E3	NT	tachykinin_on	0	100	Yes	Yes	No	Yes	3	4
289	Lig	NT	tachykinin_on	0	100	Yes	Yes	No	Yes	0	4
290	2x68	NT	tachykinin_on	0	100	No	Yes	No	Yes	4	4
291	7x31	NT	tachykinin_on	0	100	No	Yes	No	Yes	4	4
292	2x67	NT	tachykinin_on	0	100	Yes	No	No	Yes	5	4
293	1x31	NT	tachykinin_on	0	100	No	Yes	No	Yes	2	4
294	1x32	NT	tachykinin_on	0	100	No	No	No	Yes	3	4
295	7x32	NT	tachykinin_on	0	100	No	No	No	Yes	1	4
296	1x39	7x35	tachykinin_on	0	100	No	Yes	No	Yes	7	3
297	1x51	2x51	tachykinin_on	0	100	No	No	No	No	4	7
298	1x54	2x47	tachykinin_on	0	100	No	No	No	No	7	9
299	2x40	I1x50	tachykinin_on	0	100	No	Yes	No	No	8	7
300	2x37	2x39	tachykinin_on	0	100	No	No	No	No	7	8
301	2x38	2x41	tachykinin_on	0	100	No	Yes	Yes	Yes	6	5
302	2x38	I2	tachykinin_on	0	100	No	Yes	Yes	Yes	6	6
303	2x39	2x40	tachykinin_on	0	100	No	No	No	Yes	8	8
304	2x40	2x43	tachykinin_on	0	100	No	Yes	No	No	8	8
305	2x42	3x49	tachykinin_on	0	100	Yes	Yes	Yes	No	7	9
306	2x43	3x46	tachykinin_on	0	100	No	No	No	No	8	9
307	2x46	3x42	tachykinin_on	0	100	No	No	No	No	9	8
308	2x46	7x49	tachykinin_on	0	100	No	No	No	Yes	9	9
309	2x52	3x31	tachykinin_on	0	100	No	No	No	Yes	6	4
310	2x53	3x36	tachykinin_on	0	100	Yes	Yes	No	Yes	7	7
311	2x56	3x31	tachykinin_on	0	100	No	Yes	No	Yes	5	4
312	2x57	3x28	tachykinin_on	0	100	Yes	Yes	No	Yes	6	5
313	2x57	7x38	tachykinin_on	0	100	Yes	Yes	No	Yes	6	5
314	2x60	3x28	tachykinin_on	0	100	No	No	No	Yes	5	5
315	2x61	7x34	tachykinin_on	0	100	No	Yes	No	Yes	6	5
316	2x61	Lig	tachykinin_on	0	100	No	Yes	Yes	Yes	6	0
317	2x62	7x35	tachykinin_on	0	100	No	Yes	No	Yes	6	3
318	2x64	2x68	tachykinin_on	0	100	No	Yes	No	Yes	4	4
319	2x64	E2	tachykinin_on	0	100	No	Yes	Yes	Yes	4	3
320	2x64	Lig	tachykinin_on	0	100	No	Yes	Yes	Yes	4	0
321	2x68	Lig	tachykinin_on	0	100	No	Yes	Yes	Yes	4	0
322	3x24	E1x52	tachykinin_on	0	100	No	Yes	Yes	Yes	5	7
323	3x22	E2	tachykinin_on	0	100	No	No	Yes	Yes	3	3
324	3x24	3x28	tachykinin_on	0	100	No	Yes	No	Yes	5	5
325	3x25	4x65	tachykinin_on	0	100	No	No	No	No	9	5
326	3x25	E2	tachykinin_on	0	100	No	No	Yes	Yes	9	3
327	3x28	3x32	tachykinin_on	0	100	No	Yes	No	No	5	6
328	3x29	E2x50	tachykinin_on	0	100	Yes	Yes	No	Yes	5	9
329	3x29	Lig	tachykinin_on	0	100	Yes	Yes	Yes	Yes	5	0
330	3x30	4x59	tachykinin_on	0	100	No	No	No	No	6	4
331	3x31	3x32	tachykinin_on	0	100	No	Yes	No	No	4	6
332	3x33	3x37	tachykinin_on	0	100	Yes	Yes	No	Yes	5	7
333	3x34	4x54	tachykinin_on	0	100	No	No	No	No	5	4
334	3x36	3x37	tachykinin_on	0	100	No	Yes	No	Yes	7	7
335	3x37	4x56	tachykinin_on	0	100	No	Yes	No	No	7	5
336	3x37	4x57	tachykinin_on	0	100	No	Yes	No	No	7	7
337	3x37	5x461	tachykinin_on	0	100	No	Yes	No	No	7	6
338	3x40	6x48	tachykinin_on	0	100	No	No	Yes	Yes	7	8
339	3x41	4x49	tachykinin_on	0	100	No	No	No	No	5	7
340	3x46	3x50	tachykinin_on	0	100	No	No	No	No	9	9
341	3x48	3x52	tachykinin_on	0	100	No	No	No	No	5	5
342	3x50	5x58	tachykinin_on	0	100	No	No	No	Yes	9	9
343	3x52	3x56	tachykinin_on	0	100	No	No	No	Yes	5	6
344	3x55	5x60	tachykinin_on	0	100	Yes	Yes	No	No	7	4
345	4x42	I2	tachykinin_on	0	100	No	Yes	Yes	Yes	7	6
346	E2	Lig	tachykinin_on	0	100	Yes	Yes	Yes	Yes	3	0
347	E2x50	Lig	tachykinin_on	0	100	No	Yes	Yes	Yes	9	0
348	E2x51	Lig	tachykinin_on	0	100	No	No	Yes	Yes	4	0
349	5x34	E2	tachykinin_on	0	100	No	Yes	Yes	Yes	1	3
350	5x34	5x35	tachykinin_on	0	100	No	Yes	No	No	1	4
351	5x36	6x59	tachykinin_on	0	100	No	Yes	No	No	4	5
352	5x39	5x40	tachykinin_on	0	100	Yes	Yes	Yes	No	6	5
353	5x40	6x55	tachykinin_on	0	100	Yes	No	No	Yes	5	6
354	5x43	5x461	tachykinin_on	0	100	No	No	No	No	5	6
355	5x51	6x44	tachykinin_on	0	100	No	No	No	Yes	6	9
356	5x54	5x58	tachykinin_on	0	100	No	No	No	Yes	8	9
357	5x58	6x41	tachykinin_on	0	100	No	Yes	No	No	9	8
358	5x61	6x37	tachykinin_on	0	100	No	No	No	Yes	8	8
359	5x62	6x34	tachykinin_on	0	100	No	No	No	No	5	6
360	5x66	6x34	tachykinin_on	0	100	No	No	No	No	4	6
361	6x32	7x56	tachykinin_on	0	100	No	No	No	No	8	7
362	6x35	6x38	tachykinin_on	0	100	No	No	No	No	6	5
363	6x36	7x52	tachykinin_on	0	100	No	No	No	No	8	8
364	6x48	6x52	tachykinin_on	0	100	Yes	Yes	Yes	Yes	8	7
365	6x51	6x52	tachykinin_on	0	100	Yes	Yes	Yes	Yes	7	7
366	6x51	7x38	tachykinin_on	0	100	Yes	Yes	No	Yes	7	5
367	6x54	E3	tachykinin_on	0	100	No	Yes	Yes	Yes	4	3
368	6x54	7x30	tachykinin_on	0	100	No	Yes	No	No	4	4
369	6x54	7x37	tachykinin_on	0	100	No	Yes	No	No	4	6
370	6x57	E3	tachykinin_on	0	100	No	No	Yes	Yes	4	3
371	E3	Lig	tachykinin_on	0	100	Yes	Yes	Yes	Yes	3	0
372	7x29	7x33	tachykinin_on	0	100	No	No	No	No	3	5
373	7x30	Lig	tachykinin_on	0	100	No	No	Yes	Yes	4	0
374	7x31	7x32	tachykinin_on	0	100	No	Yes	No	No	4	1
375	7x31	Lig	tachykinin_on	0	100	No	Yes	Yes	Yes	4	0
376	7x34	Lig	tachykinin_on	0	100	No	Yes	Yes	Yes	5	0
377	7x38	7x42	tachykinin_on	0	100	No	Yes	No	No	5	7
378	Lig	Lig	tachykinin_on	0	100	Yes	Yes	Yes	Yes	0	0
379	1x54	2x44	tachykinin_on	0	100	No	No	No	No	7	6
380	2x52	2x56	tachykinin_on	0	100	No	No	No	Yes	6	5
381	2x53	2x57	tachykinin_on	0	100	Yes	Yes	Yes	Yes	7	6
382	2x63	E1x51	tachykinin_on	0	100	No	No	Yes	No	4	2
383	3x28	Lig	tachykinin_on	0	100	No	Yes	Yes	Yes	5	0
384	3x50	6x37	tachykinin_on	0	100	No	No	No	Yes	9	8
385	3x51	3x52	tachykinin_on	0	100	Yes	Yes	No	No	8	5
386	6x23	6x26	tachykinin_on	0	100	No	No	No	No	0	4
387	6x54	Lig	tachykinin_on	0	100	No	Yes	Yes	Yes	4	0
388	7x29	E3	tachykinin_on	0	100	No	No	Yes	Yes	3	3
389	7x31	7x35	tachykinin_on	0	100	No	Yes	No	Yes	4	3
390	1x52	1x55	tachykinin_on	0	100	No	No	No	No	6	4
391	1x53	8x48	tachykinin_on	0	100	No	No	No	Yes	8	4
392	1x56	8x48	tachykinin_on	0	100	No	No	No	Yes	8	4
393	I1x48	I1x50	tachykinin_on	0	100	No	No	No	No	6	7
394	2x37	I2	tachykinin_on	0	100	No	No	Yes	Yes	7	6
395	2x64	2x67	tachykinin_on	0	100	No	Yes	Yes	No	4	5
396	3x36	6x51	tachykinin_on	0	100	No	Yes	Yes	Yes	7	7
397	5x36	E2x52	tachykinin_on	0	100	No	Yes	Yes	No	4	4
398	5x54	6x44	tachykinin_on	0	100	No	No	No	Yes	8	9
399	7x28	Lig	tachykinin_on	0	100	No	No	Yes	Yes	0	0
400	7x53	8x47	tachykinin_on	0	100	Yes	Yes	No	No	9	8
401	7x54	8x48	tachykinin_on	0	100	No	No	No	Yes	7	4
402	2x49	3x39	tachykinin_on	0	50	No	No	No	No	8	9
403	1x59	1x60	tachykinin_on	0	50	No	No	No	No	4	5
404	3x43	7x49	tachykinin_on	0	50	No	No	No	Yes	8	9
405	2x55	2x56	tachykinin_on	0	50	No	No	No	Yes	4	5
406	6x32	7x55	tachykinin_on	0	50	No	No	No	No	8	6
407	6x37	6x40	tachykinin_on	0	50	No	Yes	No	No	8	7
408	5x61	5x62	tachykinin_on	0	50	No	No	No	No	8	5
409	1x42	7x47	tachykinin_on	0	25	No	No	No	No	7	7
410	6x47	7x43	tachykinin_on	0	50	No	No	No	No	8	5
411	5x41	6x56	tachykinin_on	0	50	No	No	No	No	5	5
412	1x47	2x51	tachykinin_on	0	50	No	No	No	No	6	7
413	8x54	8x58	tachykinin_on	0	50	No	No	No	No	6	6
414	8x48	8x52	tachykinin_on	0	25	No	Yes	No	No	4	4
415	5x68	6x26	tachykinin_on	0	50	No	No	No	No	5	4
416	5x66	5x67	tachykinin_on	0	50	No	No	No	No	4	4
417	1x60	8x56	tachykinin_on	0	25	No	No	No	No	5	3
418	3x41	5x46	tachykinin_on	0	0	No	No	No	No	5	4
419	6x30	6x35	tachykinin_on	0	50	No	No	No	No	7	6
420	1x31	1x34	tachykinin_on	0	50	No	Yes	No	No	2	4
421	2x38	4x39	tachykinin_on	0	0	No	Yes	No	No	6	2
422	5x42	5x46	tachykinin_on	0	0	No	No	No	No	4	4
423	1x44	1x48	tachykinin_on	0	0	No	No	No	No	4	4
424	5x55	6x41	tachykinin_on	0	0	No	No	No	No	4	8
425	6x23	6x25	tachykinin_on	0	0	No	No	No	No	0	3
426	6x46	6x47	tachykinin_on	0	0	No	No	No	No	5	8
427	1x40	1x44	tachykinin_on	0	0	No	No	No	No	4	4
428	4x55	4x56	tachykinin_on	0	0	No	No	No	No	4	5
429	5x45	5x46	tachykinin_on	0	0	No	No	No	No	4	4
430	1x41	1x42	tachykinin_on	0	25	No	No	No	No	5	7
431	4x52	4x56	tachykinin_on	0	0	No	No	No	No	4	5
432	6x39	6x40	tachykinin_on	0	0	No	No	No	No	5	7
433	1x34	1x37	tachykinin_on	0	0	No	No	No	No	4	5
434	3x22	3x23	tachykinin_on	0	0	No	No	No	No	3	3

Orange: nodes, hubs and links specific of tachykinin_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of tachykinin_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	tachykinin_off Avg Int. Strength	tachykinin_on Avg Int. Strength	tachykinin_off Num Of Links	tachykinin_on Num Of Links	ConSurf
1	1x35	tachykinin_off	0	50	5	3	4
2	1x50	tachykinin_off	33.3333	0	4	3	9
3	I1x51	tachykinin_off	0	0	4	3	6
4	2x48	tachykinin_off	0	0	4	2	6
5	2x67	tachykinin_off	0	0	4	3	5
6	E1x51	tachykinin_off	0	0	4	2	2
7	3x27	tachykinin_off	0	0	4	3	4
8	3x49	tachykinin_off	33.3333	0	4	2	9
9	4x50	tachykinin_off	33.3333	0	4	2	9
10	E2x52	tachykinin_off	33.3333	0	4	3	4
11	5x40	tachykinin_off	33.3333	50	4	3	5
12	6x31	tachykinin_off	0	0	5	2	5
13	7x39	tachykinin_off	66.6667	0	5	3	5
14	8x50	tachykinin_off	66.6667	25	4	3	9
15	2x41	Shared	33.3333	0	4	4	5
16	2x42	Shared	100	100	4	5	7
17	2x50	Shared	66.6667	100	5	5	9
18	2x53	Shared	33.3333	50	4	4	7
19	2x57	Shared	33.3333	75	4	5	6
20	E1x50	Shared	66.6667	50	6	4	8
21	E1x52	Shared	66.6667	25	5	4	7
22	3x29	Shared	33.3333	0	4	4	5
23	3x33	Shared	33.3333	0	4	4	5
24	3x51	Shared	33.3333	75	5	5	8
25	3x55	Shared	0	100	4	4	7
26	I2	Shared	100	100	7	8	6
27	4x61	Shared	66.6667	25	5	5	6
28	E2	Shared	100	100	10	16	3
29	5x39	Shared	66.6667	50	4	5	6
30	5x47	Shared	100	50	4	4	8
31	6x48	Shared	66.6667	100	6	7	8
32	6x51	Shared	66.6667	100	4	7	7
33	6x52	Shared	66.6667	100	4	4	7
34	E3	Shared	33.3333	100	5	10	3
35	7x53	Shared	100	50	5	4	9
36	Lig	Shared	100	100	11	21	0
37	NT	tachykinin_on	0	50	1	11	4
38	1x31	tachykinin_on	0	25	3	4	2
39	1x39	tachykinin_on	33.3333	50	3	4	7
40	2x38	tachykinin_on	0	50	2	4	6
41	2x40	tachykinin_on	0	50	2	4	8
42	2x56	tachykinin_on	0	50	1	4	5
43	2x61	tachykinin_on	0	100	2	4	6
44	2x62	tachykinin_on	33.3333	0	3	4	6
45	2x64	tachykinin_on	0	75	2	5	4
46	2x68	tachykinin_on	0	50	1	4	4
47	3x24	tachykinin_on	33.3333	0	3	4	5
48	3x28	tachykinin_on	66.6667	50	3	6	5
49	3x31	tachykinin_on	0	50	3	4	4
50	3x36	tachykinin_on	0	50	3	4	7
51	3x37	tachykinin_on	0	50	3	5	7
52	3x56	tachykinin_on	33.3333	0	3	4	6
53	4x42	tachykinin_on	0	50	3	4	7
54	E2x50	tachykinin_on	0	0	2	4	9
55	5x34	tachykinin_on	0	0	2	4	1
56	5x36	tachykinin_on	33.3333	0	3	4	4
57	5x58	tachykinin_on	33.3333	75	3	5	9
58	6x37	tachykinin_on	0	50	2	5	8
59	6x44	tachykinin_on	0	50	3	4	9
60	6x54	tachykinin_on	0	100	2	6	4
61	6x55	tachykinin_on	0	50	3	4	6
62	7x31	tachykinin_on	0	0	1	4	4
63	7x34	tachykinin_on	0	75	3	5	5
64	7x35	tachykinin_on	0	50	1	4	3
65	7x38	tachykinin_on	66.6667	75	2	5	5
66	7x49	tachykinin_on	33.3333	0	3	4	9
67	8x48	tachykinin_on	0	50	3	5	4

Orange: nodes, hubs and links specific of tachykinin_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of tachykinin_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	tachykinin_off Recurrence	tachykinin_on Recurrence	tachykinin_off Hub1?	tachykinin_on Hub1?	tachykinin_off Hub2?	tachykinin_on Hub2?	ConSurf1	ConSurf2
1	1x35	7x32	tachykinin_off	14.2135	5.29891	Yes	No	No	No	4	1
2	1x35	7x39	tachykinin_off	23.9168	0	Yes	No	Yes	No	4	5
3	1x39	2x62	tachykinin_off	11.8041	3.68722	No	Yes	No	Yes	7	6
4	7x39	7x43	tachykinin_off	17.3648	0	Yes	No	No	No	5	5
5	7x43	7x48	tachykinin_off	14.9225	9.68422	No	No	No	No	5	5
6	7x34	7x38	tachykinin_off	55.2652	8.52699	No	Yes	No	Yes	5	5
7	6x54	7x34	tachykinin_off	58.7447	1.14318	No	Yes	No	Yes	4	5
8	6x54	6x55	tachykinin_off	60.8128	2.43628	No	Yes	No	Yes	4	6
9	3x43	6x44	tachykinin_off	86.5612	0	No	No	No	Yes	8	9
10	2x46	3x43	tachykinin_off	86.0425	0	No	No	No	No	9	8
11	2x46	2x50	tachykinin_off	85.5436	3.36863	No	No	Yes	Yes	9	9
12	2x50	7x46	tachykinin_off	11.8894	4.81634	Yes	Yes	No	No	9	9
13	6x55	Lig	tachykinin_off	41.8133	1.11975	No	Yes	Yes	Yes	6	0
14	6x48	Lig	tachykinin_off	86.4627	0	Yes	Yes	Yes	Yes	8	0
15	3x32	Lig	tachykinin_off	57.1232	0	No	No	Yes	Yes	6	0
16	2x57	3x31	tachykinin_off	54.333	0	Yes	Yes	No	Yes	6	4
17	2x53	3x31	tachykinin_off	60.8128	0	Yes	Yes	No	Yes	7	4
18	2x48	2x53	tachykinin_off	56.2828	0	Yes	No	Yes	Yes	6	7
19	1x57	8x50	tachykinin_off	36.1148	0	No	No	Yes	No	7	9
20	1x58	2x44	tachykinin_off	32.0838	0	No	No	No	No	2	6
21	6x36	7x53	tachykinin_off	23.9955	0	No	No	Yes	Yes	8	9
22	6x36	8x47	tachykinin_off	19.1176	0	No	No	No	No	8	8
23	8x47	8x49	tachykinin_off	37.9333	1.49457	No	No	No	No	8	6
24	8x49	I1x50	tachykinin_off	19.3343	0	No	No	No	No	6	7
25	1x60	I1x50	tachykinin_off	16.1043	0	No	No	No	No	5	7
26	8x47	8x50	tachykinin_off	25.6303	0.15461	No	No	Yes	No	8	9
27	1x58	I1x51	tachykinin_off	31.3616	3.89337	No	No	Yes	No	2	6
28	2x48	4x50	tachykinin_off	54.7269	0	Yes	No	Yes	No	6	9
29	2x45	4x50	tachykinin_off	53.2694	3.09689	No	No	Yes	No	9	9
30	2x45	4x46	tachykinin_off	52.4685	5.57065	No	No	No	No	9	8
31	2x42	4x46	tachykinin_off	52.1468	4.94284	Yes	Yes	No	No	7	8
32	2x42	4x42	tachykinin_off	50.8863	7.73051	Yes	Yes	No	Yes	7	7
33	2x41	4x42	tachykinin_off	32.9372	9.97002	Yes	Yes	No	Yes	5	7
34	2x38	4x42	tachykinin_off	59.7689	0.243628	No	Yes	No	Yes	6	7
35	2x38	3x49	tachykinin_off	58.3771	0	No	Yes	Yes	No	6	9
36	2x67	E1x51	tachykinin_off	12.1849	0	Yes	No	Yes	No	5	2
37	E1x51	E1x52	tachykinin_off	11.3971	0	Yes	No	Yes	Yes	2	7
38	3x24	3x27	tachykinin_off	10.1169	8.24119	No	Yes	Yes	No	5	4
39	3x28	E1x50	tachykinin_off	20.4307	0	No	Yes	Yes	Yes	5	8
40	3x29	4x61	tachykinin_off	18.9798	0.431034	Yes	Yes	Yes	Yes	5	6
41	3x33	Lig	tachykinin_off	15.5987	6.09539	Yes	Yes	Yes	Yes	5	0
42	3x33	4x57	tachykinin_off	12.5197	0.824588	Yes	Yes	No	No	5	7
43	3x30	4x57	tachykinin_off	10.4648	0	No	No	No	No	6	7
44	3x40	6x44	tachykinin_off	42.1087	4.90536	No	No	No	Yes	7	9
45	3x41	5x50	tachykinin_off	36.0425	8.00693	No	No	No	No	5	9
46	3x37	3x41	tachykinin_off	13.3469	0	No	Yes	No	No	7	5
47	3x41	3x44	tachykinin_off	21.4286	0	No	No	No	No	5	7
48	3x44	5x54	tachykinin_off	17.135	3.16248	No	No	No	No	7	8
49	3x47	5x54	tachykinin_off	12.7889	0	No	No	No	No	9	8
50	3x47	5x58	tachykinin_off	10.5961	1.57421	No	No	No	Yes	9	9
51	3x49	I2	tachykinin_off	51.6019	7.99756	Yes	No	Yes	Yes	9	6
52	3x51	3x56	tachykinin_off	13.2616	8.74719	Yes	Yes	No	Yes	8	6
53	3x55	3x56	tachykinin_off	27.9674	8.11938	Yes	Yes	No	Yes	7	6
54	5x36	Lig	tachykinin_off	19.0914	0	No	Yes	Yes	Yes	4	0
55	5x36	E2	tachykinin_off	16.4653	4.33377	No	Yes	Yes	Yes	4	3
56	5x40	Lig	tachykinin_off	10.1825	0	Yes	No	Yes	Yes	5	0
57	6x52	Lig	tachykinin_off	13.9378	0	Yes	Yes	Yes	Yes	7	0
58	5x47	6x52	tachykinin_off	10.7471	5.71121	Yes	Yes	Yes	Yes	8	7
59	3x54	3x55	tachykinin_off	25.8075	0	No	No	Yes	Yes	8	7
60	3x54	5x61	tachykinin_off	24.1334	1.33527	No	No	No	No	8	8
61	5x61	6x34	tachykinin_off	22.4593	0	No	No	No	No	8	6
62	5x65	6x34	tachykinin_off	21.0347	7.76799	No	No	No	No	8	6
63	5x65	6x31	tachykinin_off	17.6208	0	No	No	Yes	No	8	5
64	8x48	8x49	tachykinin_off	15.822	0	No	Yes	No	No	4	6
65	6x48	7x45	tachykinin_off	22.5118	1.61169	Yes	Yes	No	No	8	9
66	6x47	7x45	tachykinin_off	20.6276	0	No	No	No	No	8	9
67	6x47	7x40	tachykinin_off	18.7303	2.4316	No	No	No	No	8	7
68	6x50	7x40	tachykinin_off	16.8199	0	No	No	No	No	9	7
69	6x50	7x37	tachykinin_off	14.8963	2.49719	No	No	No	No	9	6
70	7x33	7x37	tachykinin_off	12.9596	0	No	No	No	No	5	6
71	7x30	7x33	tachykinin_off	11.0097	0	No	No	No	No	4	5
72	1x55	1x60	tachykinin_off	12.8611	0	No	No	No	No	4	5
73	3x28	3x29	tachykinin_off	20.1549	0	No	Yes	Yes	Yes	5	5
74	1x39	7x39	Shared	47.2558	28.6123	No	Yes	Yes	No	7	5
75	1x39	7x38	Shared	53.3548	29.6383	No	Yes	No	Yes	7	5
76	6x51	6x55	Shared	20.818	11.6379	Yes	Yes	No	Yes	7	6
77	6x48	6x51	Shared	21.0675	86.2444	Yes	Yes	Yes	Yes	8	7
78	6x44	6x48	Shared	100	94.1951	No	Yes	Yes	Yes	9	8
79	1x50	2x50	Shared	11.8894	14.2054	Yes	No	Yes	Yes	9	9
80	2x50	7x49	Shared	77.4554	19.8838	Yes	Yes	No	Yes	9	9
81	7x49	7x53	Shared	74.7111	29.7273	No	Yes	Yes	Yes	9	9
82	7x53	8x50	Shared	52.777	21.5049	Yes	Yes	Yes	No	9	9
83	1x56	8x50	Shared	13.3009	20.3055	No	No	Yes	No	8	9
84	2x57	3x32	Shared	56.6176	11.9659	Yes	Yes	No	No	6	6
85	1x57	2x44	Shared	32.9832	34.2391	No	No	No	No	7	6
86	2x41	I1x51	Shared	30.8101	11.6614	Yes	Yes	Yes	No	5	6
87	4x61	Lig	Shared	24.8293	13.3527	Yes	Yes	Yes	Yes	6	0
88	3x40	5x50	Shared	40.0998	11.146	No	No	No	No	7	9
89	3x56	I2	Shared	42.739	22.8776	No	Yes	Yes	Yes	6	6
90	7x31	7x35	tachykinin_on	0	11.666	No	Yes	No	Yes	4	3
91	6x51	7x38	tachykinin_on	0	27.4035	Yes	Yes	No	Yes	7	5
92	6x51	Lig	tachykinin_on	1.70037	72.2498	Yes	Yes	Yes	Yes	7	0
93	Lig	NT	tachykinin_on	0	15.55	Yes	Yes	No	Yes	0	4
94	1x42	7x39	tachykinin_on	2.51444	23.9365	No	No	Yes	No	7	5
95	1x42	7x47	tachykinin_on	0	19.2232	No	No	No	No	7	7
96	2x43	7x53	tachykinin_on	1.96297	50.4076	No	No	Yes	Yes	8	9
97	2x43	3x46	tachykinin_on	0	80.6081	No	No	No	No	8	9
98	3x46	3x50	tachykinin_on	0	81.0954	No	No	No	No	9	9
99	3x50	5x58	tachykinin_on	0	69.6589	No	No	No	Yes	9	9
100	5x54	5x58	tachykinin_on	0	98.9552	No	No	No	Yes	8	9
101	5x54	6x44	tachykinin_on	0	100	No	No	No	Yes	8	9
102	7x54	8x54	tachykinin_on	1.9761	10.4479	No	No	No	No	7	6
103	7x54	8x48	tachykinin_on	0	11.8909	No	No	No	Yes	7	4
104	1x56	8x48	tachykinin_on	0	18.0566	No	No	No	Yes	8	4
105	1x54	2x48	tachykinin_on	1.74632	35.3495	No	No	Yes	No	7	6
106	2x48	2x52	tachykinin_on	1.74632	35.9117	Yes	No	No	No	6	6
107	2x52	3x31	tachykinin_on	0	32.2433	No	No	No	Yes	6	4
108	3x31	3x32	tachykinin_on	0	33.3162	No	Yes	No	No	4	6
109	3x28	3x32	tachykinin_on	0	22.5122	No	Yes	No	No	5	6
110	3x28	Lig	tachykinin_on	0	30.3645	No	Yes	Yes	Yes	5	0
111	1x54	2x44	tachykinin_on	0	34.5343	No	No	No	No	7	6
112	1x57	2x40	tachykinin_on	3.87999	34.0189	No	No	No	Yes	7	8
113	2x40	2x43	tachykinin_on	0	49.0302	No	Yes	No	No	8	8
114	2x37	2x39	tachykinin_on	0	63.0013	No	No	No	No	7	8
115	2x39	2x40	tachykinin_on	0	64.6692	No	No	No	Yes	8	8
116	2x38	I2	tachykinin_on	0	13.0763	No	Yes	Yes	Yes	6	6
117	2x37	I2	tachykinin_on	0	61.2865	No	No	Yes	Yes	7	6
118	4x42	I2	tachykinin_on	0	17.9442	No	Yes	Yes	Yes	7	6
119	3x30	4x59	tachykinin_on	0	27.9657	No	No	No	No	6	4
120	4x59	4x60	tachykinin_on	2.02206	23.6413	No	No	No	No	4	8
121	4x60	5x39	tachykinin_on	3.85373	27.1177	No	No	Yes	Yes	8	6
122	5x39	E2	tachykinin_on	1.5822	13.7181	Yes	Yes	Yes	Yes	6	3
123	4x63	4x64	tachykinin_on	2.05488	11.6379	No	No	No	No	4	5
124	4x64	E2	tachykinin_on	3.73556	13.0201	No	No	Yes	Yes	5	3
125	3x30	4x54	tachykinin_on	6.31565	16.8057	No	No	No	No	6	4
126	3x34	4x54	tachykinin_on	0	11.2116	No	No	No	No	5	4
127	5x61	6x37	tachykinin_on	0	27.4691	No	No	No	Yes	8	8
128	5x58	6x37	tachykinin_on	3.93251	26.9209	No	Yes	No	Yes	9	8
129	5x61	5x62	tachykinin_on	0	24.8829	No	No	No	No	8	5
130	5x62	6x34	tachykinin_on	0	23.4586	No	No	No	No	5	6
131	5x66	6x34	tachykinin_on	0	14.7161	No	No	No	No	4	6
132	5x66	6x31	tachykinin_on	5.48845	10.209	No	No	Yes	No	4	5
133	6x37	6x40	tachykinin_on	0	10.5369	No	Yes	No	No	8	7
134	7x47	7x48	tachykinin_on	9.99869	14.4725	No	No	No	No	7	5
135	7x31	Lig	tachykinin_on	0	12.7624	No	Yes	Yes	Yes	4	0
136	E2	Lig	tachykinin_on	0	36.4786	Yes	Yes	Yes	Yes	3	0
137	E3	Lig	tachykinin_on	0	10.3729	Yes	Yes	Yes	Yes	3	0
138	4x61	5x39	tachykinin_on	6.09244	11.666	Yes	Yes	Yes	Yes	6	6
139	3x36	6x48	tachykinin_on	1.36555	13.6479	No	Yes	Yes	Yes	7	8
140	3x50	6x37	tachykinin_on	0	11.9331	No	No	No	Yes	9	8

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
1x28	1x31	Shared	12.6333	6.3175	4	1	2	2
2x57	2x61	Shared	4.08667	6.1325	5	1	2	1
2x57	3x31	tachykinin_off	6.04	0	5	1	2	2
2x57	3x32	Shared	7.6	6.52	5	1	2	1
2x60	3x24	Shared	6.31	8.1025	0	1	2	2
2x61	3x28	Shared	8.92667	7.08	0	1	1	1
2x64	E1x50	Shared	8.03667	5.065	0	1	1	2
2x67	E1x51	tachykinin_off	7.26	0	7	1	2	2
3x25	E1x50	tachykinin_off	4.35333	0	6	1	2	2
3x28	E1x50	tachykinin_off	7.40667	0	0	1	1	2
E1x50	E2x50	Shared	9.14333	6.8575	6	0	2	1
3x25	E2x50	Shared	7.28	3.64	6	1	2	1
3x28	3x29	tachykinin_off	8.08	0	0	1	1	1
3x29	4x61	Shared	6.6	5.61	1	1	1	1
3x29	4x65	Shared	5.46333	5.96	1	1	1	2
3x29	E2x52	tachykinin_off	6.61	0	1	1	1	2
3x32	Lig	tachykinin_off	11.4233	0	0	1	1	0
3x33	4x61	Shared	5.49	2.745	1	1	1	1
3x33	5x43	tachykinin_off	4.61	0	1	1	1	2
3x33	Lig	Shared	7.31667	7.7675	1	1	1	0
3x36	5x461	tachykinin_off	6.05667	0	1	1	1	1
3x36	6x48	Shared	6.03	5.055	1	1	1	1
3x36	Lig	tachykinin_off	4.78667	0	1	1	1	0
3x40	6x44	Shared	10.4667	5.6525	0	1	2	2
4x61	5x39	Shared	7.51333	7.0475	1	1	1	2
4x61	Lig	Shared	19.2133	4.42	1	1	1	0
4x64	E2	Shared	16.1367	10.365	1	1	2	1
4x65	E2x52	tachykinin_off	4.64333	0	1	0	2	2
E2	E2	Shared	41.98	34.5025	1	1	1	1
E2	E2x51	Shared	8.73	3.175	1	1	1	1
E2	E2x52	Shared	6.65333	6.755	1	1	1	2
5x35	E2	Shared	8.90667	5.7375	0	1	2	1
5x36	E2	Shared	17.1367	9.0325	1	1	1	1
5x39	E2	Shared	5.46667	5.305	1	1	2	1
5x36	Lig	tachykinin_off	4.18667	0	1	1	1	0
5x39	5x43	Shared	5.88667	6.625	1	1	2	2
5x40	6x56	tachykinin_off	4.71667	0	0	0	1	2
5x40	6x59	Shared	6.53333	7.0775	0	0	1	2
5x40	Lig	tachykinin_off	13.9967	0	0	0	1	0
5x44	6x52	Shared	9.12667	8.79	0	0	2	1
5x44	6x56	Shared	5.40333	2.58	0	0	2	2
5x461	6x52	tachykinin_off	3.97667	0	1	0	1	1
5x461	Lig	tachykinin_off	5.25667	0	1	0	1	0
5x47	6x52	Shared	6.89667	4.6275	0	0	2	1
6x44	6x48	Shared	10.3567	7.0175	0	1	2	1
6x48	6x51	Shared	8.68667	7.19	1	1	1	1
6x48	7x41	Shared	5.18667	4.8625	1	1	1	2
6x48	7x45	Shared	6.58667	6.175	1	1	1	2
6x48	Lig	tachykinin_off	5.60667	0	1	1	1	0
6x51	6x55	Shared	8.93333	11.3025	1	1	1	1
6x51	7x41	Shared	4.62333	5.0975	1	1	1	2
6x51	Lig	Shared	19.1133	7.5875	1	1	1	0
6x52	Lig	tachykinin_off	5.50333	0	1	1	1	0
6x54	6x55	Shared	8.93333	6.1	0	1	1	1
6x54	7x34	Shared	7.56333	13.34	0	1	1	1
6x55	Lig	Shared	18.56	9.705	1	1	1	0
6x57	6x58	tachykinin_off	4.92667	0	0	0	2	2
E3	E3	Shared	19.3767	12.63	3	1	1	1
7x34	7x38	Shared	9.98	8.75	0	1	1	2
4x61	E2x52	Shared	4.11667	5.98	1	1	1	2
2x64	E1x51	tachykinin_off	4.63333	0	0	1	1	2
1x28	NT	tachykinin_off	3.81	0	4	1	2	1
2x68	E2	Shared	3.8	5.3275	0	1	1	1
6x61	E3	Shared	3.63333	3.5425	3	1	2	1
3x33	4x57	Shared	3.25	3.25	1	1	1	2
5x33	5x36	Shared	3.15	4.3875	0	0	2	1
5x31	E2	Shared	2.54667	4.9575	1	0	2	1
2x53	3x31	tachykinin_off	2.48667	0	0	0	2	2
5x40	5x41	tachykinin_off	2.21	0	0	0	1	2
6x58	E3	Shared	2.14667	10.545	3	0	2	1
1x31	7x32	tachykinin_off	2.13333	0	4	1	2	2
2x67	7x31	tachykinin_off	2.06	0	7	1	2	1
7x33	7x37	tachykinin_off	2.05	0	0	0	2	2
2x65	7x34	Shared	1.33333	2.67	0	0	2	1
7x30	E3	Shared	1.21	3.93	3	1	1	1
7x29	7x32	tachykinin_off	1.17	0	0	1	2	2
7x30	7x33	tachykinin_off	1.02333	0	3	1	1	2
NT	NT	tachykinin_on	0	11.83	0	1	1	1
E2	NT	tachykinin_on	0	8.4775	1	1	1	1
E3	NT	tachykinin_on	0	3.73	3	1	1	1
Lig	NT	tachykinin_on	0	11.075	1	1	0	1
2x68	NT	tachykinin_on	0	4.95	0	1	1	1
7x31	NT	tachykinin_on	0	14.1925	0	1	1	1
2x67	NT	tachykinin_on	0	3.805	7	1	2	1
1x31	NT	tachykinin_on	0	2.88	4	1	2	1
1x32	NT	tachykinin_on	0	6.6225	0	1	2	1
7x32	NT	tachykinin_on	0	3.28	0	1	2	1
2x53	3x36	tachykinin_on	0	5.2475	0	0	2	1
2x57	3x28	tachykinin_on	0	2.87	5	1	2	1
2x57	7x38	tachykinin_on	0	3.5625	5	1	2	2
2x60	3x28	tachykinin_on	0	11.2575	0	1	2	1
2x61	7x34	tachykinin_on	0	4.3625	0	1	1	1
2x61	Lig	tachykinin_on	0	3.6	0	1	1	0
2x64	2x68	tachykinin_on	0	2.6175	0	1	1	1
2x64	E2	tachykinin_on	0	12.1825	0	1	1	1
2x64	Lig	tachykinin_on	0	8.8825	0	1	1	0
2x68	Lig	tachykinin_on	0	6.645	0	1	1	0
3x22	E2	tachykinin_on	0	4.42	0	1	2	1
3x24	3x28	tachykinin_on	0	4.9175	0	1	2	1
3x25	4x65	tachykinin_on	0	3.01	6	1	2	2
3x25	E2	tachykinin_on	0	6.78	6	1	2	1
3x28	3x32	tachykinin_on	0	3.4325	0	1	1	1
3x29	E2x50	tachykinin_on	0	2.755	1	1	1	1
3x29	Lig	tachykinin_on	0	2.7475	1	1	1	0
3x31	3x32	tachykinin_on	0	5.055	5	1	2	1
3x33	3x37	tachykinin_on	0	5.02	1	1	1	2
3x36	3x37	tachykinin_on	0	5.04	1	1	1	2
3x37	4x57	tachykinin_on	0	2.77	0	1	2	2
3x37	5x461	tachykinin_on	0	12.8725	0	1	2	1
3x40	6x48	tachykinin_on	0	4.6975	0	1	2	1
E2	Lig	tachykinin_on	0	15.93	1	1	1	0
E2x50	Lig	tachykinin_on	0	4.825	6	1	1	0
E2x51	Lig	tachykinin_on	0	6.3425	0	1	1	0
5x34	E2	tachykinin_on	0	4.99	0	1	2	1
5x34	5x35	tachykinin_on	0	3.76	0	1	2	2
5x36	6x59	tachykinin_on	0	5.52	1	1	1	2
5x39	5x40	tachykinin_on	0	7.0775	1	1	2	1
5x40	6x55	tachykinin_on	0	5.3725	0	0	1	1
5x43	5x461	tachykinin_on	0	4.2225	0	0	2	1
6x48	6x52	tachykinin_on	0	2.9075	1	1	1	1
6x51	6x52	tachykinin_on	0	6.6175	1	1	1	1
6x51	7x38	tachykinin_on	0	4.135	1	1	1	2
6x54	E3	tachykinin_on	0	8.9275	0	1	1	1
6x54	7x30	tachykinin_on	0	7.345	0	1	1	1
6x54	7x37	tachykinin_on	0	3.77	0	1	1	2
6x57	E3	tachykinin_on	0	4.1525	0	0	2	1
E3	Lig	tachykinin_on	0	7.055	3	1	1	0
7x29	7x33	tachykinin_on	0	3.2775	0	1	2	2
7x30	Lig	tachykinin_on	0	4.71	3	1	1	0
7x31	7x32	tachykinin_on	0	3.2	0	1	1	2
7x31	Lig	tachykinin_on	0	7.6125	0	1	1	0
7x34	Lig	tachykinin_on	0	11.6075	0	1	1	0
2x53	2x57	tachykinin_on	0	3.155	0	0	2	2
3x28	Lig	tachykinin_on	0	2.8875	0	1	1	0
6x54	Lig	tachykinin_on	0	2.9775	0	1	1	0
7x29	E3	tachykinin_on	0	7.8725	0	1	2	1
7x31	7x35	tachykinin_on	0	2.9925	0	1	1	2
2x64	2x67	tachykinin_on	0	3.265	0	1	1	2
3x36	6x51	tachykinin_on	0	3.59	1	1	1	1
5x36	E2x52	tachykinin_on	0	4.47	1	1	1	2
7x28	Lig	tachykinin_on	0	4.84	0	0	1	0
5x41	6x56	tachykinin_on	0	2.14	0	0	2	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	tachykinin_off	nk1_off
	tachykinin_on	nk1_on nk2_on

Network Difference
Value	tachykinin_off	tachykinin_on
I_min	3.91	2.5925
Number of Linked Nodes	257	254
Number of Specific Nodes	6 (2.33%)	3 (1.18%)
Number of Shared Nodes	251 (97.67%)	251 (98.82%)
Number of Links	285	326
Number of Specific Links	108 (37.89%)	149 (45.71%)
Number of Shared Links	177 (62.11%)	177 (54.29%)
Number of Hubs	36	53
Number of Specific Hubs	14 (38.89%)	31 (58.49%)
Number of Shared Hubs	22 (61.11%)	22 (41.51%)
Average % Shared Neighbours (Jaccard)	46.71
Average % Shared Neighbours (Otsuka)	56.89
Average % Shared Neighbours (Overlap Coefficient)	67.25
Average % Shared Cliques (k3-6)	52.19
Graphlets Similarity	0.655206

Paths Difference
Value	tachykinin_off	tachykinin_on
Number Of Nodes in MetaPath	89	67
Specific Nodes in MetaPath	50 (56.18%)	28 (41.79%)
Shared Nodes in MetaPath	251 (97.67%)	251 (97.67%)
Number Of Links MetaPath	89	67
Specific Links in MetaPath	73 (82.02%)	51 (76.12%)
Shared Links in MetaPath	177 (62.11%)	177 (62.11%)
Number of Shortest Paths	40220	55060
Length Of Smallest Path	3	3
Average Path Length	14.5577	12.5965
Length of Longest Path	34	28
Minimum Path Strength	0.523333	0.76
Average Path Strength	6.56835	5.17813
Maximum Path Strength	19.1633	12.4813
Minimum Path Correlation	0.7	0.7
Average Path Correlation	0.922511	0.911983
Maximum Path Correlation	0.99	0.99
Minimum % Of Corr. Nodes	3.125	4.54545
Average % Of Corr. Nodes	47.652	44.2647
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	36.4755	48.006
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

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