CodeBK0
NameN-(3-chlorophenyl)pyridine-2-carboxamide
Synonyms
Identifier
FormulaC12 H9 Cl N2 O
Molecular Weight232.666
SMILES
PubChem836002
Formal Charge0
Total Atoms25
Total Chiral Atoms0
Total Bonds26
Total Aromatic Bonds12
Networks2
 missing image

This ligand is also present in the following 2 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8JD6 C Aminoacid Metabotropic Glutamate mGlu4; mGlu4 Homo Sapiens Phosphoserine VU0364770 Gi3/Beta1/Gamma2 3.4 2023-06-21 doi.org/10.1038/s41422-023-00830-2

A 2D representation of the interactions of BK0 in 8JD6
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:I796 R:R:Y792 13.3 5 No Yes 8 9 2 2
R:R:Y792 S:S:L828 5.86 5 Yes No 9 6 2 1
R:R:I796 S:S:L828 4.28 5 No No 8 6 2 1
R:R:L799 X:X:?1 7.22 0 No Yes 6 0 1 0
R:R:F801 R:R:I802 3.77 51 Yes No 9 7 2 1
R:R:I802 X:X:?1 5.32 0 No Yes 7 0 1 0
R:R:P803 X:X:?1 17.14 0 No Yes 9 0 1 0
S:S:L590 S:S:P591 4.93 0 No No 4 8 1 2
S:S:L590 X:X:?1 8.25 0 No Yes 4 0 1 0
S:S:P591 S:S:V824 5.3 0 No No 8 7 2 1
S:S:F801 S:S:W798 10.02 5 Yes Yes 9 9 2 2
S:S:S825 S:S:W798 4.94 5 No Yes 8 9 1 2
S:S:F801 S:S:S825 7.93 5 Yes No 9 8 2 1
S:S:I804 S:S:T821 9.12 5 No No 7 8 1 1
S:S:I804 X:X:?1 5.32 5 No Yes 7 0 1 0
S:S:T821 X:X:?1 4.4 5 No Yes 8 0 1 0
S:S:V824 X:X:?1 18.88 0 No Yes 7 0 1 0
S:S:S825 X:X:?1 6.72 5 No Yes 8 0 1 0
S:S:L828 X:X:?1 4.13 5 No Yes 6 0 1 0
S:S:T820 X:X:?1 3.3 0 No Yes 8 0 1 0
R:R:A800 S:S:I804 3.25 0 No No 7 7 2 1
R:R:C795 R:R:L799 3.17 0 No No 6 6 2 1
S:S:I817 S:S:T820 3.04 0 No No 5 8 2 1
StatisticsValue
Average Number Of Links10.00
Average Number Of Links With An Hub0.00
Average Interaction Strength8.07
Average Nodes In Shell20.00
Average Hubs In Shell5.00
Average Links In Shell23.00
Average Links Mediated by Hubs In Shell16.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links10.00
Average Number Of Links With An Hub0.00
Average Interaction Strength8.07
Average Nodes In Shell20.00
Average Hubs In Shell4.50
Average Links In Shell23.00
Average Links Mediated by Hubs In Shell15.00

missing image


Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

missing image


Location of the nodes interacting with this ligand

(Click to enlarge 🔍)