CodeBK0
NameN-(3-chlorophenyl)pyridine-2-carboxamide
Synonyms
Identifier~{N}-(3-chlorophenyl)pyridine-2-carboxamide
FormulaC12 H9 Cl N2 O
Molecular Weight232.666
SMILESc1ccnc(c1)C(=O)Nc2cccc(c2)Cl
PubChem836002
Formal Charge0
Total Atoms25
Total Chiral Atoms0
Total Bonds26
Total Aromatic Bonds12
Networks1
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This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8JD6 C Aminoacid Metabotropic glutamate mGlu4; mGlu4 Homo sapiens Phosphoserine N-(3-chlorophenyl)pyridine-2-carboxamide Gi3/Beta1/Gamma2 3.4 2023-06-21 10.1038/s41422-023-00830-2

A 2D representation of the interactions of BK0 in 8JD6
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
S:S:L590 S:S:P591 4.93 0 No No 4 8 1 2
S:S:L590 X:X:?1 8.25 0 No Yes 4 0 1 0
S:S:P591 S:S:V824 5.3 0 No No 8 7 2 1
S:S:F801 S:S:W798 10.02 4 Yes Yes 9 9 2 2
S:S:S825 S:S:W798 4.94 4 No Yes 8 9 1 2
S:S:F801 S:S:S825 7.93 4 Yes No 9 8 2 1
S:S:I804 S:S:T821 9.12 4 No No 7 8 1 1
S:S:I804 X:X:?1 5.32 4 No Yes 7 0 1 0
S:S:T821 X:X:?1 4.4 4 No Yes 8 0 1 0
S:S:V824 X:X:?1 18.88 0 No Yes 7 0 1 0
S:S:S825 X:X:?1 6.72 4 No Yes 8 0 1 0
R:R:Y792 S:S:L828 5.86 4 Yes No 9 6 2 1
R:R:I796 S:S:L828 4.28 4 No No 8 6 2 1
S:S:L828 X:X:?1 4.13 4 No Yes 6 0 1 0
R:R:I796 R:R:Y792 13.3 4 No Yes 8 9 2 2
R:R:L799 X:X:?1 7.22 0 No Yes 6 0 1 0
R:R:F801 R:R:I802 3.77 51 Yes No 9 7 2 1
R:R:I802 X:X:?1 5.32 0 No Yes 7 0 1 0
R:R:P803 X:X:?1 17.14 0 No Yes 9 0 1 0
S:S:T820 X:X:?1 3.3 0 No Yes 8 0 1 0
R:R:A800 S:S:I804 3.25 0 No No 7 7 2 1
R:R:C795 R:R:L799 3.17 52 No No 6 6 2 1
S:S:I817 S:S:T820 3.04 0 No No 5 8 2 1
StatisticsValue
Average Number Of Links10.00
Average Number Of Links With An Hub0.00
Average Interaction Strength8.07
Average Nodes In Shell20.00
Average Hubs In Shell5.00
Average Links In Shell23.00
Average Links Mediated by Hubs In Shell16.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links10.00
Average Number Of Links With An Hub0.00
Average Interaction Strength8.07
Average Nodes In Shell20.00
Average Hubs In Shell5.00
Average Links In Shell23.00
Average Links Mediated by Hubs In Shell16.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)