psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:E14	A:A:K10	8.1	No	No	0	3	3
2	A:A:A11	A:A:E14	4.53	No	No	0	3	3
3	A:A:A11	A:A:R15	4.15	No	No	0	3	4
4	A:A:S16	B:B:K89	6.12	No	Yes	0	7	9
5	A:A:I19	B:B:K89	8.72	No	Yes	0	9	9
6	A:A:D20	B:B:K89	8.3	No	Yes	0	6	9
7	A:A:L23	A:A:R24	6.07	No	No	0	5	4
8	A:A:L23	B:B:I80	4.28	No	Yes	0	5	8
9	A:A:R24	B:B:L55	8.5	No	No	0	4	6
10	A:A:D26	A:A:G27	6.71	No	No	0	5	5
11	A:A:D26	B:B:K78	5.53	No	No	0	5	8
12	A:A:K29	A:A:K32	11.49	No	No	0	2	4
13	A:A:E33	A:A:Y195	13.47	No	No	0	6	4
14	A:A:E33	A:A:K197	8.1	No	Yes	0	6	7
15	A:A:F196	A:A:V34	5.24	Yes	No	0	7	5
16	A:A:T219	A:A:V34	4.76	No	No	0	8	5
17	A:A:F199	A:A:K35	6.2	Yes	No	0	6	9
18	A:A:K35	A:A:V218	6.07	No	No	0	9	9
19	A:A:F196	A:A:L36	4.87	Yes	No	0	7	7
20	A:A:L36	A:A:M198	4.24	No	Yes	0	7	7
21	A:A:L37	A:A:L39	5.54	No	Yes	0	9	9
22	A:A:F215	A:A:L37	7.31	Yes	No	0	9	9
23	A:A:I221	A:A:L37	8.56	No	No	0	7	9
24	A:A:L38	A:A:M198	4.24	No	Yes	0	9	7
25	A:A:F223	A:A:L39	10.96	No	Yes	0	9	9
26	A:A:I253	A:A:L39	4.28	No	Yes	0	8	9
27	A:A:G40	A:A:K46	6.97	No	Yes	0	9	9
28	A:A:K46	A:A:S44	4.59	Yes	No	0	9	9
29	A:A:G45	A:A:T48	5.46	No	No	31	9	9
30	A:A:G45	A:A:N269	5.09	No	Yes	31	9	9
31	A:A:D200	A:A:K46	6.91	No	Yes	0	9	9
32	A:A:N269	A:A:T48	5.85	Yes	No	31	9	9
33	A:A:C224	A:A:I49	6.55	No	No	32	7	7
34	A:A:F267	A:A:I49	10.05	Yes	No	32	9	7
35	A:A:T187	A:A:V50	4.76	No	No	0	7	7
36	A:A:N331	A:A:Q52	6.6	No	No	0	8	9
37	A:A:F189	A:A:M53	12.44	Yes	No	16	9	9
38	A:A:M53	A:A:V332	4.56	No	Yes	16	9	7
39	A:A:G183	A:A:Q204	6.58	No	Yes	0	8	9
40	A:A:G183	B:B:N119	5.09	No	No	0	8	9
41	A:A:I184	A:A:Q204	4.12	No	Yes	10	8	9
42	A:A:I184	B:B:W99	3.52	No	Yes	10	8	9
43	A:A:I184	B:B:L117	5.71	No	Yes	10	8	9
44	A:A:D200	A:A:V185	4.38	No	No	0	9	5
45	A:A:E186	A:A:H188	16	No	No	10	9	3
46	A:A:E186	A:A:K197	6.75	No	Yes	10	9	7
47	A:A:E186	A:A:F199	4.66	No	Yes	10	9	6
48	A:A:M198	A:A:T187	4.52	Yes	No	0	7	7
49	A:A:H188	A:A:Y195	23.96	No	No	0	3	4
50	A:A:H188	A:A:K197	13.1	No	Yes	10	3	7
51	A:A:F189	A:A:F196	13.93	Yes	Yes	0	9	7
52	A:A:F189	A:A:M198	6.22	Yes	Yes	0	9	7
53	A:A:F189	A:A:V332	3.93	Yes	Yes	16	9	7
54	A:A:D191	A:A:K192	12.44	No	No	16	5	4
55	A:A:D191	A:A:V332	5.84	No	Yes	16	5	7
56	A:A:D191	A:A:F336	4.78	No	No	16	5	8
57	A:A:K192	A:A:Q333	6.78	No	No	0	4	5
58	A:A:F336	A:A:K192	16.13	No	No	16	8	4
59	A:A:D193	R:R:R686	8.34	No	No	0	3	6
60	A:A:F196	A:A:L194	8.53	Yes	No	0	7	4
61	A:A:F196	A:A:V335	3.93	Yes	No	0	7	8
62	A:A:F196	A:A:V339	3.93	Yes	No	0	7	8
63	A:A:F199	A:A:K197	8.69	Yes	Yes	10	6	7
64	A:A:F199	A:A:F215	7.5	Yes	Yes	10	6	9
65	A:A:F199	B:B:W99	18.04	Yes	Yes	10	6	9
66	A:A:Q204	A:A:W211	4.38	Yes	Yes	0	9	9
67	A:A:Q204	B:B:L117	3.99	Yes	Yes	10	9	9
68	A:A:S206	B:B:Y145	5.09	No	Yes	0	8	8
69	A:A:E207	A:A:K210	5.4	No	Yes	0	9	9
70	A:A:R208	A:A:W211	5	No	Yes	0	9	9
71	A:A:R208	A:A:S252	5.27	No	No	0	9	7
72	A:A:K210	B:B:M188	4.32	Yes	No	0	9	8
73	A:A:K210	B:B:C204	4.85	Yes	No	33	9	7
74	A:A:K210	B:B:D228	4.15	Yes	No	33	9	9
75	A:A:I212	A:A:W211	5.87	No	Yes	0	9	9
76	A:A:F215	A:A:W211	6.01	Yes	Yes	0	9	9
77	A:A:F259	A:A:I212	7.54	Yes	No	0	9	9
78	A:A:C214	A:A:H213	7.37	No	No	0	8	8
79	A:A:H213	A:A:W258	6.35	No	Yes	21	8	5
80	A:A:H213	B:B:W332	8.46	No	Yes	21	8	9
81	A:A:C214	B:B:Y59	9.41	No	Yes	0	8	8
82	A:A:F215	B:B:W99	12.03	Yes	Yes	10	9	9
83	A:A:E216	A:A:W258	4.36	No	Yes	0	8	5
84	A:A:T219	R:R:V688	6.35	No	No	0	8	6
85	A:A:F259	A:A:I221	6.28	Yes	No	0	9	7
86	A:A:I221	A:A:I264	5.89	No	Yes	0	7	6
87	A:A:F267	A:A:I222	7.54	Yes	No	0	9	7
88	A:A:F223	A:A:F250	18.22	No	Yes	8	9	9
89	A:A:F223	A:A:L266	3.65	No	Yes	8	9	9
90	A:A:C224	A:A:F267	4.19	No	Yes	32	7	9
91	A:A:S246	A:A:V225	4.85	No	No	8	9	7
92	A:A:F307	A:A:V225	10.49	Yes	No	8	8	7
93	A:A:A226	A:A:K270	4.82	No	No	0	8	9
94	A:A:L227	A:A:L268	4.15	No	No	0	7	8
95	A:A:F274	A:A:L227	8.53	No	No	0	8	7
96	A:A:I303	A:A:L227	11.42	No	No	0	8	7
97	A:A:K270	A:A:S228	12.24	No	No	0	9	9
98	A:A:D229	A:A:R242	13.1	No	No	0	8	9
99	A:A:M243	A:A:Y230	3.59	No	Yes	0	8	9
100	A:A:F274	A:A:Y230	7.22	No	Yes	0	8	9
101	A:A:K277	A:A:Y230	14.33	No	Yes	0	9	9
102	A:A:L283	A:A:Y230	8.21	Yes	Yes	0	7	9
103	A:A:C286	A:A:Y230	5.38	No	Yes	0	6	9
104	A:A:D231	A:A:K277	8.3	No	No	0	9	9
105	A:A:E236	A:A:L232	11.93	No	No	0	9	8
106	A:A:L232	A:A:R242	17.01	No	No	0	8	9
107	A:A:E239	A:A:L234	6.63	No	No	0	4	8
108	A:A:D237	A:A:E238	16.89	No	No	0	8	4
109	A:A:E238	A:A:M240	8.12	No	No	0	4	6
110	A:A:H244	A:A:N241	16.58	No	No	0	4	9
111	A:A:M243	A:A:Y287	5.99	No	Yes	0	8	8
112	A:A:H244	A:A:Y287	5.44	No	Yes	0	4	8
113	A:A:F307	A:A:S246	3.96	Yes	No	8	8	9
114	A:A:M247	A:A:Y287	7.18	No	Yes	0	6	8
115	A:A:F307	A:A:M247	6.22	Yes	No	0	8	6
116	A:A:F250	A:A:I264	3.77	Yes	Yes	8	9	6
117	A:A:F250	A:A:L266	9.74	Yes	Yes	8	9	9
118	A:A:F250	A:A:F307	11.79	Yes	Yes	8	9	8
119	A:A:F250	A:A:L310	3.65	Yes	No	0	9	4
120	A:A:F250	A:A:I319	5.02	Yes	Yes	8	9	6
121	A:A:D251	A:A:N255	10.77	No	No	35	5	8
122	A:A:D251	A:A:L310	4.07	No	No	0	5	4
123	A:A:D251	A:A:R312	3.57	No	No	35	5	5
124	A:A:F259	A:A:I253	5.02	Yes	No	0	9	8
125	A:A:C254	A:A:N255	4.72	No	No	0	5	8
126	A:A:C254	A:A:K317	4.85	No	No	0	5	7
127	A:A:N255	A:A:R312	8.44	No	No	35	8	5
128	A:A:F259	A:A:N256	7.25	Yes	No	0	9	8
129	A:A:K257	A:A:W258	10.44	No	Yes	0	5	5
130	A:A:W258	B:B:W332	4.69	Yes	Yes	21	5	9
131	A:A:R313	A:A:T260	16.82	No	No	0	4	3
132	A:A:K317	A:A:T260	6.01	No	No	0	7	3
133	A:A:N346	A:A:T262	8.77	No	No	0	4	8
134	A:A:S263	A:A:V342	8.08	No	No	0	7	6
135	A:A:I264	A:A:K317	7.27	Yes	No	0	6	7
136	A:A:I264	A:A:I319	4.42	Yes	Yes	8	6	6
137	A:A:I265	A:A:Y320	3.63	No	Yes	0	9	8
138	A:A:F307	A:A:L266	4.87	Yes	Yes	8	8	9
139	A:A:L266	A:A:T321	5.9	Yes	No	8	9	4
140	A:A:F267	A:A:T324	5.19	Yes	No	0	9	9
141	A:A:F267	A:A:N331	12.08	Yes	No	0	9	8
142	A:A:F267	A:A:F334	7.5	Yes	Yes	0	9	4
143	A:A:F267	A:A:V335	3.93	Yes	No	0	9	8
144	A:A:F323	A:A:L268	3.65	No	No	0	5	8
145	A:A:N269	A:A:T324	10.24	Yes	No	0	9	9
146	A:A:K270	A:A:L273	8.46	No	No	0	9	6
147	A:A:D272	A:A:K271	9.68	No	No	0	9	5
148	A:A:K271	A:A:Y296	5.97	No	No	0	5	4
149	A:A:D272	A:A:S326	8.83	No	No	0	9	9
150	A:A:E275	A:A:E276	3.81	No	No	0	5	5
151	A:A:E275	A:A:Y296	17.96	No	No	0	5	4
152	A:A:K279	A:A:R280	9.9	No	No	0	3	3
153	A:A:P282	A:A:T284	5.25	No	No	0	5	4
154	A:A:L283	A:A:Y287	3.52	Yes	Yes	0	7	8
155	A:A:L283	A:A:Y290	5.86	Yes	No	0	7	7
156	A:A:C286	A:A:Y287	10.75	No	Yes	0	6	8
157	A:A:Y287	A:A:Y302	9.93	Yes	Yes	34	8	6
158	A:A:Q306	A:A:Y287	19.16	No	Yes	34	5	8
159	A:A:E289	A:A:P288	7.86	No	No	0	6	6
160	A:A:E298	A:A:Y290	5.61	No	No	0	5	7
161	A:A:Y290	A:A:Y302	10.92	No	Yes	0	7	6
162	A:A:E298	A:A:G292	4.91	No	No	0	5	7
163	A:A:S293	A:A:T295	4.8	No	No	0	3	5
164	A:A:E298	A:A:S293	4.31	No	No	0	5	3
165	A:A:E297	A:A:T295	4.23	No	No	0	4	5
166	A:A:F323	A:A:Y296	11.35	No	No	0	5	4
167	A:A:Q306	A:A:Y302	15.78	No	Yes	34	5	6
168	A:A:I303	A:A:Q306	10.98	No	No	0	8	5
169	A:A:E308	A:A:Q304	12.74	No	No	8	3	5
170	A:A:Q304	A:A:T321	7.09	No	No	8	5	4
171	A:A:E308	A:A:I319	12.3	No	Yes	8	3	6
172	A:A:E308	A:A:T321	8.47	No	No	8	3	4
173	A:A:D309	A:A:K314	4.15	No	No	0	4	3
174	A:A:K314	A:A:N311	4.2	No	No	0	3	7
175	A:A:I319	A:A:N311	8.5	Yes	No	0	6	7
176	A:A:D315	A:A:T316	7.23	No	No	0	1	3
177	A:A:E318	A:A:Y320	16.83	No	Yes	25	4	8
178	A:A:E318	A:A:K345	12.15	No	Yes	25	4	5
179	A:A:A338	A:A:Y320	5.34	No	Yes	0	7	8
180	A:A:D341	A:A:Y320	9.2	No	Yes	25	7	8
181	A:A:K345	A:A:Y320	3.58	Yes	Yes	25	5	8
182	A:A:F334	A:A:H322	32.81	Yes	No	0	4	9
183	A:A:C325	A:A:D328	6.22	No	No	0	7	9
184	A:A:A338	A:A:F334	4.16	No	Yes	0	7	4
185	A:A:F336	A:A:T340	7.78	No	No	0	8	6
186	A:A:D341	A:A:K345	9.68	No	Yes	25	7	5
187	A:A:N346	A:A:V342	4.43	No	No	0	4	6
188	A:A:I343	R:R:V688	6.14	No	No	0	7	6
189	A:A:I344	R:R:F681	6.28	No	Yes	0	6	9
190	A:A:I344	R:R:G684	3.53	No	No	0	6	7
191	A:A:K345	A:A:Y354	9.55	Yes	No	0	5	5
192	A:A:N347	R:R:I680	4.25	No	Yes	0	7	9
193	A:A:N347	R:R:Q683	3.96	No	Yes	0	7	5
194	A:A:L348	A:A:Y354	4.69	Yes	No	0	8	5
195	A:A:L348	R:R:I680	4.28	Yes	Yes	6	8	9
196	A:A:L348	R:R:F681	4.87	Yes	Yes	6	8	9
197	A:A:L348	R:R:F781	8.53	Yes	Yes	6	8	9
198	A:A:C351	R:R:I694	4.91	Yes	Yes	0	4	7
199	A:A:C351	R:R:P696	5.65	Yes	No	0	4	6
200	A:A:L353	R:R:R676	4.86	No	Yes	0	7	8
201	A:A:L353	R:R:I677	4.28	No	No	0	7	9
202	A:A:Y354	R:R:K619	5.97	No	No	0	5	7
203	B:B:G41	B:B:V40	3.68	No	No	0	1	3
204	B:B:R283	B:B:V40	11.77	No	No	36	9	3
205	B:B:D298	B:B:V40	5.84	No	No	36	9	3
206	B:B:Q44	B:B:R42	10.51	No	No	0	4	2
207	B:B:M45	B:B:W339	8.14	No	Yes	0	4	9
208	B:B:R46	B:B:R48	8.53	No	No	0	5	7
209	B:B:K337	B:B:T47	6.01	Yes	No	17	6	3
210	B:B:T47	B:B:W339	4.85	No	Yes	17	3	9
211	B:B:N340	B:B:R48	21.69	No	No	0	9	7
212	B:B:R49	B:B:T87	9.06	No	No	0	7	5
213	B:B:I338	B:B:R49	5.01	No	No	0	5	7
214	B:B:R49	G:G:E47	11.63	No	No	0	7	3
215	B:B:K337	B:B:T50	15.02	Yes	No	0	6	3
216	B:B:L51	B:B:W82	12.53	Yes	Yes	0	9	9
217	B:B:L51	B:B:T87	4.42	Yes	No	0	9	5
218	B:B:L336	B:B:L51	6.92	No	Yes	0	7	9
219	B:B:I338	B:B:L51	4.28	No	Yes	0	5	9
220	B:B:F335	B:B:R52	7.48	No	No	0	4	7
221	B:B:H54	B:B:I58	11.93	Yes	No	0	9	9
222	B:B:H54	B:B:S72	5.58	Yes	No	0	9	9
223	B:B:H54	B:B:S74	5.58	Yes	No	0	9	9
224	B:B:H54	B:B:I80	5.3	Yes	Yes	0	9	8
225	B:B:D76	B:B:L55	4.07	No	No	0	9	6
226	B:B:K57	B:B:Y59	15.53	No	Yes	21	9	8
227	B:B:K57	B:B:W332	19.73	No	Yes	21	9	9
228	B:B:I58	B:B:L336	4.28	No	No	0	9	7
229	B:B:Q75	B:B:Y59	11.27	No	Yes	0	9	8
230	B:B:W332	B:B:Y59	8.68	Yes	Yes	21	9	8
231	B:B:A60	B:B:C103	3.61	No	No	0	7	8
232	B:B:L70	B:B:M61	7.07	No	No	0	5	6
233	B:B:C317	B:B:M61	4.86	No	No	0	7	6
234	B:B:H62	B:B:R150	11.28	No	No	0	6	6
235	B:B:L70	B:B:W63	9.11	No	No	0	5	7
236	B:B:S84	B:B:W63	4.94	No	No	0	5	7
237	B:B:T321	B:B:W63	13.34	No	No	0	7	7
238	B:B:G64	B:B:Y105	4.35	No	Yes	0	5	6
239	B:B:D66	B:B:L69	6.79	No	No	0	8	5
240	B:B:S67	B:B:T321	9.59	No	No	0	5	7
241	B:B:D83	B:B:R68	3.57	No	No	0	8	5
242	B:B:R68	B:B:Y85	21.61	No	No	0	5	4
243	B:B:L69	B:B:Y105	9.38	No	Yes	0	5	6
244	B:B:L70	B:B:W82	5.69	No	Yes	0	5	9
245	B:B:C103	B:B:V71	5.12	No	No	0	8	8
246	B:B:V71	B:B:Y105	8.83	No	Yes	0	8	6
247	B:B:D76	B:B:S74	8.83	No	No	0	9	9
248	B:B:Q75	B:B:W99	8.76	No	Yes	0	9	9
249	B:B:D76	B:B:K78	8.3	No	No	0	9	8
250	B:B:K78	B:B:P94	10.04	No	No	0	8	5
251	B:B:I93	B:B:L79	4.28	Yes	No	0	7	7
252	B:B:L79	B:B:L95	8.3	No	No	0	7	8
253	B:B:I80	B:B:W82	8.22	Yes	Yes	30	8	9
254	B:B:I80	B:B:K89	7.27	Yes	Yes	30	8	9
255	B:B:H91	B:B:I81	10.61	Yes	No	26	5	7
256	B:B:I81	B:B:Y105	10.88	No	Yes	26	7	6
257	B:B:I81	B:B:L126	4.28	No	No	26	7	5
258	B:B:K89	B:B:W82	12.76	Yes	Yes	30	9	9
259	B:B:D83	B:B:N88	9.42	No	No	0	8	7
260	B:B:I338	B:B:S84	4.64	No	No	0	5	5
261	B:B:M325	B:B:Y85	5.99	Yes	No	0	5	4
262	B:B:N88	B:B:T86	10.24	No	No	0	7	6
263	B:B:H91	B:B:V90	9.69	Yes	No	0	5	5
264	B:B:H91	B:B:L126	3.86	Yes	No	26	5	5
265	B:B:H91	B:B:V133	4.15	Yes	No	0	5	4
266	B:B:I93	B:B:P94	5.08	Yes	No	0	7	5
267	B:B:I93	B:B:Y124	7.25	Yes	Yes	0	7	6
268	B:B:I93	B:B:V133	10.75	Yes	No	0	7	4
269	B:B:L95	B:B:V100	7.45	No	No	0	8	9
270	B:B:L95	B:B:Y124	3.52	No	Yes	0	8	6
271	B:B:D118	B:B:S97	8.83	No	No	0	9	8
272	B:B:S98	B:B:W99	6.18	No	Yes	0	8	9
273	B:B:L117	B:B:W99	4.56	Yes	Yes	10	9	9
274	B:B:C114	B:B:V100	6.83	No	No	0	8	9
275	B:B:M101	B:B:S147	10.73	No	No	0	9	9
276	B:B:A104	B:B:F151	4.16	No	Yes	0	7	9
277	B:B:L126	B:B:Y105	3.52	No	Yes	26	5	6
278	B:B:D154	B:B:S108	8.83	No	No	0	6	6
279	B:B:N110	B:B:Y111	15.12	No	Yes	0	4	4
280	B:B:K127	B:B:N110	8.39	No	No	0	4	4
281	B:B:I123	B:B:Y111	3.63	Yes	Yes	0	6	4
282	B:B:D154	B:B:Y111	5.75	No	Yes	0	6	4
283	B:B:V112	B:B:Y124	3.79	No	Yes	0	8	6
284	B:B:A113	B:B:F151	4.16	No	Yes	0	9	9
285	B:B:C114	B:B:Y124	5.38	No	Yes	0	8	6
286	B:B:G115	B:B:L146	5.13	No	No	0	9	7
287	B:B:L117	B:B:Y145	3.52	Yes	Yes	0	9	8
288	B:B:D118	B:B:I120	7	No	No	0	9	6
289	B:B:C121	B:B:L139	4.76	No	Yes	0	8	9
290	B:B:C121	B:B:C149	3.64	No	No	14	8	8
291	B:B:C121	B:B:T159	6.76	No	Yes	14	8	9
292	B:B:S122	B:B:Y124	6.36	No	Yes	0	8	6
293	B:B:I123	B:B:L139	4.28	Yes	Yes	0	6	9
294	B:B:F151	B:B:I123	3.77	Yes	Yes	0	9	6
295	B:B:I123	B:B:I171	4.42	Yes	No	0	6	6
296	B:B:V135	B:B:Y124	5.05	No	Yes	0	4	6
297	B:B:N125	B:B:T128	5.85	Yes	No	0	4	3
298	B:B:N125	B:B:R134	3.62	Yes	No	0	4	3
299	B:B:N125	B:B:S136	5.96	Yes	No	0	4	4
300	B:B:E130	B:B:T128	14.11	No	No	0	3	3
301	B:B:E130	B:B:N132	6.57	No	No	0	3	3
302	B:B:E130	B:B:R134	6.98	No	No	0	3	3
303	B:B:L139	B:B:W169	27.33	Yes	Yes	0	9	8
304	B:B:H142	B:B:T159	8.21	No	Yes	14	9	9
305	B:B:H142	B:B:S161	12.55	No	No	0	9	9
306	B:B:H142	B:B:W169	14.81	No	Yes	14	9	8
307	B:B:D163	B:B:G144	5.03	Yes	No	0	9	8
308	B:B:S147	B:B:Y145	6.36	No	Yes	0	9	8
309	B:B:G162	B:B:Y145	5.79	No	Yes	0	9	8
310	B:B:D186	B:B:Y145	9.2	No	Yes	0	9	8
311	B:B:M188	B:B:Y145	10.78	No	Yes	0	8	8
312	B:B:L146	B:B:S161	6.01	No	No	0	7	9
313	B:B:C148	B:B:L190	4.76	No	No	0	6	5
314	B:B:C149	B:B:T159	6.76	No	Yes	14	8	9
315	B:B:L192	B:B:R150	4.86	No	No	0	5	6
316	B:B:F151	B:B:I157	6.28	Yes	No	0	9	7
317	B:B:L152	B:B:Q156	3.99	Yes	No	0	3	5
318	B:B:L152	B:B:L192	6.92	Yes	No	0	3	5
319	B:B:L152	B:B:V213	4.47	Yes	No	0	3	4
320	B:B:D170	B:B:N155	5.39	Yes	No	7	9	3
321	B:B:I171	B:B:N155	5.66	No	No	0	6	3
322	B:B:E172	B:B:N155	13.15	No	No	7	6	3
323	B:B:L168	B:B:Q156	3.99	No	No	0	6	5
324	B:B:I157	B:B:T159	4.56	No	Yes	0	7	9
325	B:B:L192	B:B:V158	4.47	No	No	0	5	5
326	B:B:F199	B:B:V158	7.87	No	No	0	9	5
327	B:B:T159	B:B:W169	7.28	Yes	Yes	14	9	8
328	B:B:L190	B:B:S160	9.01	No	No	0	5	6
329	B:B:D163	B:B:S161	4.42	Yes	No	0	9	9
330	B:B:D163	B:B:T165	7.23	Yes	No	0	9	7
331	B:B:G185	B:B:T164	3.64	No	No	0	5	6
332	B:B:T165	B:B:T181	6.28	No	No	0	7	2
333	B:B:C166	B:B:F180	4.19	No	Yes	0	8	7
334	B:B:A167	B:B:W169	3.89	No	Yes	14	4	8
335	B:B:A167	B:B:Q176	6.06	No	No	14	4	4
336	B:B:L168	B:B:T177	4.42	No	No	7	6	4
337	B:B:L168	B:B:T178	7.37	No	No	7	6	4
338	B:B:Q176	B:B:W169	10.95	No	Yes	14	4	8
339	B:B:D170	B:B:E172	11.69	Yes	No	7	9	6
340	B:B:D170	B:B:T173	4.34	Yes	No	0	9	5
341	B:B:D170	B:B:T177	4.34	Yes	No	7	9	4
342	B:B:T177	B:B:T178	4.71	No	No	7	4	4
343	B:B:F180	B:B:T178	10.38	Yes	No	7	7	4
344	B:B:F180	B:B:F199	8.57	Yes	No	7	7	9
345	B:B:F180	B:B:W211	11.02	Yes	Yes	7	7	8
346	B:B:H183	B:B:S201	6.97	Yes	No	7	9	9
347	B:B:A203	B:B:H183	4.39	No	Yes	0	8	9
348	B:B:H183	B:B:S207	5.58	Yes	No	0	9	5
349	B:B:H183	B:B:K209	15.72	Yes	Yes	7	9	6
350	B:B:H183	B:B:W211	8.46	Yes	Yes	7	9	8
351	B:B:D205	B:B:T184	4.34	No	No	0	9	3
352	B:B:S207	B:B:T184	4.8	No	No	0	5	3
353	B:B:C204	B:B:D186	4.67	No	No	0	7	9
354	B:B:S201	B:B:V187	6.46	No	No	0	9	9
355	B:B:M188	B:B:N230	5.61	No	No	0	8	9
356	B:B:I232	B:B:S189	6.19	No	No	0	8	7
357	B:B:F234	B:B:S191	5.28	Yes	No	0	5	8
358	B:B:A193	B:B:F234	4.16	No	Yes	0	4	5
359	B:B:D195	B:B:R197	10.72	No	No	0	5	5
360	B:B:L198	B:B:L210	6.92	No	No	0	3	5
361	B:B:L198	B:B:R219	3.64	No	No	0	3	5
362	B:B:F199	B:B:W211	6.01	No	Yes	7	9	8
363	B:B:F234	B:B:V200	3.93	Yes	No	0	5	6
364	B:B:F241	B:B:V200	14.42	Yes	No	0	6	6
365	B:B:S201	B:B:W211	7.41	No	Yes	7	9	8
366	B:B:G202	B:B:I232	3.53	No	No	0	6	8
367	B:B:C204	B:B:D228	4.67	No	No	33	7	9
368	B:B:K209	B:B:W211	12.76	Yes	Yes	7	6	8
369	B:B:C218	B:B:K209	9.7	No	Yes	0	5	6
370	B:B:L210	B:B:Q220	10.65	No	No	0	5	7
371	B:B:D212	B:B:R214	9.53	No	No	0	9	9
372	B:B:D212	B:B:E215	14.29	No	No	0	9	3
373	B:B:E215	B:B:M217	5.41	No	No	0	3	3
374	B:B:C218	B:B:T221	5.07	No	No	0	5	7
375	B:B:Q220	B:B:R219	11.68	No	No	0	7	5
376	B:B:F222	B:B:F241	6.43	Yes	Yes	11	8	6
377	B:B:F222	B:B:F253	6.43	Yes	Yes	11	8	6
378	B:B:G224	B:B:T223	3.64	No	No	0	6	2
379	B:B:H225	B:B:I229	3.98	Yes	No	0	9	7
380	B:B:H225	B:B:S245	11.16	Yes	No	11	9	9
381	B:B:H225	B:B:T249	5.48	Yes	Yes	11	9	6
382	B:B:H225	B:B:R251	11.28	Yes	Yes	11	9	8
383	B:B:D247	B:B:S227	5.89	No	No	0	9	6
384	B:B:D246	B:B:N230	5.39	No	No	0	9	9
385	B:B:N230	B:B:T274	5.85	No	No	0	9	8
386	B:B:F241	B:B:I232	3.77	Yes	No	0	6	8
387	B:B:C233	B:B:F278	9.78	No	Yes	0	3	7
388	B:B:F235	B:B:P236	7.22	Yes	No	0	6	7
389	B:B:F235	B:B:N237	12.08	Yes	Yes	0	6	5
390	B:B:A240	B:B:F235	5.55	No	Yes	0	6	6
391	B:B:F235	B:B:F278	9.65	Yes	Yes	0	6	7
392	B:B:F235	B:B:G282	4.52	Yes	No	0	6	9
393	B:B:G238	B:B:N237	5.09	No	Yes	0	7	5
394	B:B:N237	B:B:N239	6.81	Yes	No	0	5	2
395	B:B:N237	G:G:K32	15.39	Yes	No	0	5	5
396	B:B:L255	B:B:N239	4.12	No	No	0	6	2
397	B:B:F241	B:B:T243	3.89	Yes	No	11	6	8
398	B:B:F241	B:B:F253	9.65	Yes	Yes	11	6	6
399	B:B:A242	B:B:L252	4.73	No	No	0	4	7
400	B:B:A242	B:B:F278	4.16	No	Yes	0	4	7
401	B:B:F253	B:B:T243	7.78	Yes	No	11	6	8
402	B:B:G244	B:B:I273	5.29	No	No	0	5	6
403	B:B:S245	B:B:T249	4.8	No	Yes	11	9	6
404	B:B:D246	B:B:G272	5.03	No	No	0	9	4
405	B:B:A248	B:B:Y289	4	No	Yes	0	5	7
406	B:B:R251	B:B:T249	5.17	Yes	Yes	11	8	6
407	B:B:F253	B:B:R251	6.41	Yes	Yes	11	6	8
408	B:B:E260	B:B:R251	4.65	No	Yes	0	6	8
409	B:B:R251	B:B:T263	11.64	Yes	No	0	8	1
410	B:B:L252	B:B:Y264	4.69	No	No	0	7	5
411	B:B:D254	B:B:R256	7.15	No	No	0	9	9
412	B:B:D254	G:G:K29	4.15	No	No	0	9	4
413	B:B:A257	B:B:R256	6.91	No	No	0	7	9
414	B:B:A257	B:B:Q259	4.55	No	No	0	7	6
415	B:B:L285	B:B:Y264	8.21	No	No	0	6	5
416	B:B:A302	B:B:Y264	4	No	No	0	2	5
417	B:B:H266	B:B:I269	22.54	No	No	27	4	4
418	B:B:H266	B:B:Y289	11.98	No	Yes	27	4	7
419	B:B:H266	B:B:W297	11.64	No	Yes	27	4	8
420	B:B:D267	B:B:N268	4.04	No	No	0	3	4
421	B:B:I269	B:B:Y289	4.84	No	Yes	27	4	7
422	B:B:C271	B:B:G272	3.92	No	No	0	5	4
423	B:B:C271	B:B:Y289	4.03	No	Yes	0	5	7
424	B:B:I273	B:B:Y289	13.3	No	Yes	0	6	7
425	B:B:R314	B:B:T274	6.47	No	No	0	8	8
426	B:B:G319	B:B:S277	3.71	No	No	0	5	5
427	B:B:F278	B:B:L285	4.87	Yes	No	0	7	6
428	B:B:S279	B:B:S281	4.89	No	No	0	9	9
429	B:B:K280	G:G:D36	6.91	No	No	0	1	5
430	B:B:G282	B:B:S281	3.71	No	No	0	9	9
431	B:B:D298	B:B:R283	9.53	No	No	36	9	9
432	B:B:L284	B:B:L286	4.15	Yes	No	38	5	7
433	B:B:L284	B:B:V296	4.47	Yes	No	38	5	5
434	B:B:L285	B:B:W297	10.25	No	Yes	0	6	8
435	B:B:L286	B:B:V296	4.47	No	No	38	7	5
436	B:B:C294	B:B:G288	3.92	No	No	0	5	7
437	B:B:W297	B:B:Y289	7.72	Yes	Yes	27	8	7
438	B:B:D290	B:B:R314	19.06	No	No	0	6	8
439	B:B:D312	B:B:F292	4.78	No	No	0	5	4
440	B:B:N293	B:B:N295	5.45	No	No	0	5	6
441	B:B:N293	B:B:V307	4.43	No	No	0	5	3
442	B:B:C294	B:B:L308	4.76	No	No	0	5	7
443	B:B:C294	B:B:V315	5.12	No	No	0	5	7
444	B:B:N295	B:B:W297	5.65	No	Yes	0	6	8
445	B:B:N295	B:B:R304	4.82	No	No	0	6	5
446	B:B:D298	B:B:K301	12.44	No	No	0	9	5
447	B:B:A299	B:B:L300	4.73	No	No	0	5	6
448	B:B:L308	B:B:W339	15.94	No	Yes	0	7	9
449	B:B:H311	B:B:S331	16.74	No	No	17	9	9
450	B:B:D333	B:B:H311	16.39	Yes	No	17	9	9
451	B:B:H311	B:B:K337	14.41	No	Yes	17	9	6
452	B:B:N313	B:B:W332	6.78	No	Yes	0	7	9
453	B:B:D333	B:B:N313	5.39	Yes	No	0	9	7
454	B:B:R314	B:B:W332	28.99	No	Yes	0	8	9
455	B:B:T329	B:B:V315	4.76	No	No	0	8	7
456	B:B:S331	B:B:V315	8.08	No	No	0	9	7
457	B:B:S316	B:B:W332	4.94	No	Yes	0	9	9
458	B:B:C317	B:B:G330	3.92	No	No	0	7	5
459	B:B:D323	B:B:G324	5.03	No	No	0	7	9
460	B:B:D323	B:B:M325	4.16	No	Yes	37	7	5
461	B:B:D323	G:G:Y40	20.69	No	No	37	7	6
462	B:B:M325	G:G:Y40	4.79	Yes	No	37	5	6
463	B:B:A326	B:B:N340	4.69	No	No	0	7	9
464	B:B:T329	B:B:W339	7.28	No	Yes	0	8	9
465	B:B:D333	B:B:S331	4.42	Yes	No	17	9	9
466	B:B:D333	B:B:F335	13.14	Yes	No	0	9	4
467	B:B:F335	B:B:K337	3.72	No	Yes	0	4	6
468	B:B:K337	B:B:W339	9.28	Yes	Yes	17	6	9
469	G:G:K29	G:G:V30	6.07	No	No	0	4	8
470	G:G:A39	G:G:D36	6.18	No	No	0	3	5
471	G:G:H44	G:G:K46	15.72	No	No	0	6	1
472	L:L:?1	R:R:K74	4.78	Yes	Yes	1	0	5
473	L:L:?1	R:R:R78	5.15	Yes	Yes	1	0	4
474	L:L:?1	R:R:S159	8.91	Yes	Yes	1	0	9
475	L:L:?1	R:R:T182	5	Yes	Yes	1	0	8
476	L:L:?1	R:R:Y230	31.82	Yes	Yes	1	0	7
477	L:L:?1	R:R:S313	3.82	Yes	No	1	0	6
478	L:L:?1	R:R:K405	8.37	Yes	Yes	1	0	4
479	M:M:?1	S:S:K74	10.76	Yes	Yes	3	0	5
480	M:M:?1	S:S:R78	10.3	Yes	Yes	3	0	4
481	M:M:?1	S:S:S159	3.82	Yes	No	3	0	9
482	M:M:?1	S:S:A180	5.35	Yes	No	3	0	6
483	M:M:?1	S:S:Y230	26.84	Yes	Yes	3	0	7
484	M:M:?1	S:S:S313	10.19	Yes	No	3	0	6
485	M:M:?1	S:S:K317	3.59	Yes	No	0	0	6
486	M:M:?1	S:S:K405	7.18	Yes	Yes	3	0	4
487	R:R:N41	R:R:R44	7.23	No	No	0	5	4
488	R:R:R44	R:R:S42	11.86	No	No	0	4	3
489	R:R:L106	R:R:S42	4.5	No	No	0	5	3
490	R:R:I105	R:R:I43	5.89	No	No	1	8	4
491	R:R:I43	R:R:N359	8.5	No	Yes	1	4	7
492	R:R:I43	R:R:W361	4.7	No	Yes	1	4	5
493	R:R:R104	R:R:R44	6.4	Yes	No	0	5	4
494	R:R:G102	R:R:I45	3.53	No	No	0	9	4
495	R:R:A103	R:R:I45	4.87	No	No	0	7	4
496	R:R:I45	R:R:R358	3.76	No	No	0	4	4
497	R:R:G47	R:R:T100	3.64	No	No	0	9	7
498	R:R:D48	R:R:I99	5.6	No	Yes	0	8	5
499	R:R:D48	R:R:T100	7.23	No	No	0	8	7
500	R:R:D48	R:R:L434	4.07	No	No	0	8	3
501	R:R:I49	R:R:L101	5.71	Yes	Yes	0	6	9
502	R:R:I49	R:R:V151	7.68	Yes	No	0	6	4
503	R:R:I49	R:R:L420	5.71	Yes	No	0	6	8
504	R:R:R104	R:R:T50	3.88	Yes	No	0	5	4
505	R:R:E148	R:R:T50	7.06	No	No	0	4	4
506	R:R:T50	R:R:V150	4.76	No	No	0	4	5
507	R:R:F122	R:R:G52	4.52	Yes	No	39	5	8
508	R:R:G52	R:R:V153	5.52	No	No	39	8	6
509	R:R:L54	R:R:T108	5.9	No	No	0	6	6
510	R:R:F55	R:R:L79	8.53	Yes	No	0	9	5
511	R:R:F55	R:R:M82	4.98	Yes	No	1	9	8
512	R:R:F55	R:R:I105	5.02	Yes	No	1	9	8
513	R:R:F55	R:R:Y179	10.32	Yes	Yes	1	9	8
514	R:R:K74	R:R:P56	8.36	Yes	No	1	5	5
515	R:R:P56	R:R:S110	3.56	No	No	1	5	4
516	R:R:P56	R:R:S157	7.13	No	Yes	1	5	5
517	R:R:H58	R:R:V57	4.15	Yes	Yes	1	8	6
518	R:R:L79	R:R:V57	5.96	No	Yes	0	5	6
519	R:R:D107	R:R:V57	8.76	Yes	Yes	1	9	6
520	R:R:V57	R:R:W361	9.81	Yes	Yes	1	6	5
521	R:R:C67	R:R:H58	4.42	No	Yes	1	9	8
522	R:R:H58	R:R:L70	10.29	Yes	No	0	8	5
523	R:R:D107	R:R:H58	10.08	Yes	Yes	1	9	8
524	R:R:C109	R:R:H58	5.9	Yes	Yes	1	7	8
525	R:R:G59	R:R:K71	5.23	No	No	1	3	5
526	R:R:G59	R:R:S110	3.71	No	No	1	3	4
527	R:R:N286	R:R:R60	7.23	No	No	0	5	2
528	R:R:E259	R:R:E63	8.88	No	No	0	3	1
529	R:R:C109	R:R:C67	7.28	Yes	No	1	7	9
530	R:R:D368	R:R:E69	3.9	No	No	0	3	4
531	R:R:K71	R:R:K74	15.8	No	Yes	1	5	5
532	R:R:K71	R:R:S110	4.59	No	No	1	5	4
533	R:R:E73	R:R:K72	5.4	Yes	Yes	1	2	4
534	R:R:F365	R:R:K72	9.93	Yes	Yes	1	6	4
535	R:R:D368	R:R:K72	11.06	No	Yes	0	3	4
536	R:R:K72	R:R:N369	11.19	Yes	Yes	1	4	3
537	R:R:E73	R:R:H77	11.08	Yes	Yes	1	2	6
538	R:R:E403	R:R:E73	5.07	Yes	Yes	1	5	2
539	R:R:K74	R:R:R78	9.9	Yes	Yes	1	5	4
540	R:R:K74	R:R:S157	4.59	Yes	Yes	1	5	5
541	R:R:E287	R:R:K74	6.75	No	Yes	0	3	5
542	R:R:F365	R:R:I76	16.33	Yes	No	0	6	5
543	R:R:F348	R:R:H77	7.92	Yes	Yes	1	7	6
544	R:R:H77	R:R:Y400	4.36	Yes	Yes	1	6	5
545	R:R:E403	R:R:H77	8.62	Yes	Yes	1	5	6
546	R:R:R78	R:R:S157	9.22	Yes	Yes	1	4	5
547	R:R:R78	R:R:Y179	9.26	Yes	Yes	1	4	8
548	R:R:E403	R:R:R78	6.98	Yes	Yes	1	5	4
549	R:R:K405	R:R:R78	9.9	Yes	Yes	1	4	4
550	R:R:L79	R:R:N359	6.87	No	Yes	0	5	7
551	R:R:E80	R:R:L83	3.98	Yes	No	0	8	5
552	R:R:E80	R:R:Y347	7.86	Yes	No	1	8	7
553	R:R:E80	R:R:F348	7	Yes	Yes	1	8	7
554	R:R:E80	R:R:R351	4.65	Yes	Yes	1	8	5
555	R:R:E80	R:R:N356	5.26	Yes	No	1	8	4
556	R:R:E80	R:R:F362	8.16	Yes	Yes	1	8	5
557	R:R:A81	R:R:F344	4.16	No	No	28	7	8
558	R:R:A81	R:R:V406	5.09	No	No	28	7	6
559	R:R:I105	R:R:M82	4.37	No	No	1	8	8
560	R:R:L83	R:R:R358	15.79	No	No	0	5	4
561	R:R:F84	R:R:R88	8.55	No	No	0	7	8
562	R:R:F84	R:R:Y347	9.28	No	No	0	7	7
563	R:R:A85	R:R:V413	5.09	No	No	0	8	9
564	R:R:L101	R:R:L86	4.15	Yes	No	0	9	7
565	R:R:D87	R:R:R358	9.53	No	No	0	7	4
566	R:R:R88	R:R:Y414	5.14	No	No	0	8	8
567	R:R:I458	R:R:R88	7.52	No	No	0	3	8
568	R:R:I89	R:R:L95	5.71	No	Yes	0	9	7
569	R:R:I89	R:R:L101	4.28	No	Yes	0	9	9
570	R:R:N90	R:R:T100	8.77	No	No	0	9	7
571	R:R:L101	R:R:N90	6.87	Yes	No	0	9	9
572	R:R:D92	R:R:P93	6.44	No	No	0	7	3
573	R:R:D92	R:R:D94	3.99	No	No	0	7	3
574	R:R:D92	R:R:L95	4.07	No	Yes	0	7	7
575	R:R:H418	R:R:L95	6.43	No	Yes	0	6	7
576	R:R:H421	R:R:L95	3.86	No	Yes	0	7	7
577	R:R:I99	R:R:L96	9.99	Yes	No	0	5	9
578	R:R:G433	R:R:I99	3.53	No	Yes	0	3	5
579	R:R:F122	R:R:R104	5.34	Yes	Yes	0	5	5
580	R:R:L106	R:R:Q118	13.31	No	No	0	5	5
581	R:R:F122	R:R:L106	7.31	Yes	No	0	5	5
582	R:R:C109	R:R:D107	4.67	Yes	Yes	1	7	9
583	R:R:D107	R:R:W361	7.82	Yes	Yes	1	9	5
584	R:R:C109	R:R:H114	8.85	Yes	No	0	7	3
585	R:R:R111	R:R:T113	5.17	No	No	0	5	3
586	R:R:D112	R:R:S160	8.83	Yes	No	0	4	5
587	R:R:D112	R:R:M164	12.48	Yes	Yes	2	4	5
588	R:R:D112	S:S:R191	10.72	Yes	Yes	2	4	5
589	R:R:T113	S:S:R170	6.47	No	Yes	0	3	5
590	R:R:H114	R:R:Q118	11.13	No	No	0	3	5
591	R:R:A115	R:R:V161	5.09	No	Yes	0	7	4
592	R:R:L116	R:R:M164	7.07	Yes	Yes	2	5	5
593	R:R:L116	S:S:N167	4.12	Yes	Yes	2	5	5
594	R:R:L116	S:S:I168	4.28	Yes	Yes	2	5	5
595	R:R:L116	S:S:L171	8.3	Yes	No	0	5	5
596	R:R:E117	S:S:R170	5.82	No	Yes	0	4	5
597	R:R:S119	R:R:V165	4.85	No	No	0	6	5
598	R:R:L120	R:R:Q124	9.32	No	No	0	5	7
599	R:R:L120	S:S:L171	6.92	No	No	0	5	5
600	R:R:F122	R:R:V153	7.87	Yes	No	39	5	6
601	R:R:F172	R:R:V123	18.35	No	No	0	6	5
602	R:R:G152	R:R:V151	3.68	No	No	0	8	4
603	R:R:L169	R:R:V153	5.96	No	No	0	6	6
604	R:R:G155	R:R:Q176	4.93	No	Yes	0	8	8
605	R:R:G155	R:R:S178	3.71	No	No	0	8	9
606	R:R:S157	R:R:Y179	7.63	Yes	Yes	1	5	8
607	R:R:S159	R:R:S181	6.52	Yes	No	0	9	8
608	R:R:S159	R:R:Y230	6.36	Yes	Yes	1	9	7
609	R:R:S162	R:R:S181	6.52	No	No	0	7	8
610	R:R:L186	R:R:S162	4.5	Yes	No	40	8	7
611	R:R:F195	R:R:S162	5.28	Yes	No	40	8	7
612	R:R:I163	R:R:L186	4.28	No	Yes	0	6	8
613	R:R:I163	R:R:Y192	9.67	No	No	0	6	5
614	R:R:I163	R:R:S229	4.64	No	No	0	6	6
615	R:R:M164	S:S:N167	7.01	Yes	Yes	2	5	5
616	R:R:M164	S:S:R191	3.72	Yes	Yes	2	5	5
617	R:R:Q176	R:R:V165	5.73	Yes	No	0	8	5
618	R:R:A166	R:R:Y192	4	No	No	0	7	5
619	R:R:A166	R:R:F195	4.16	No	Yes	0	7	8
620	R:R:I168	R:R:N167	5.66	No	No	2	5	5
621	R:R:N167	S:S:L116	5.49	No	Yes	2	5	5
622	R:R:N167	S:S:M164	11.22	No	Yes	2	5	5
623	R:R:I168	S:S:L116	5.71	No	Yes	2	5	5
624	R:R:I168	S:S:I168	4.42	No	Yes	2	5	5
625	R:R:L169	R:R:Q176	7.99	No	Yes	0	6	8
626	R:R:L171	R:R:R170	4.86	Yes	No	0	5	5
627	R:R:D193	R:R:R170	19.06	No	No	0	6	5
628	R:R:R170	S:S:T113	5.17	No	No	0	5	3
629	R:R:L171	S:S:L116	4.15	Yes	Yes	0	5	5
630	R:R:L171	S:S:E117	6.63	Yes	No	0	5	4
631	R:R:L171	S:S:L120	5.54	Yes	No	0	5	5
632	R:R:F172	S:S:L120	8.53	No	No	0	6	5
633	R:R:F194	R:R:K173	6.2	Yes	No	0	7	4
634	R:R:F194	R:R:P175	4.33	Yes	Yes	0	7	8
635	R:R:L446	R:R:P175	6.57	No	Yes	0	6	8
636	R:R:F195	R:R:Q176	11.71	Yes	Yes	0	8	8
637	R:R:I177	R:R:M416	4.37	No	No	0	7	6
638	R:R:I177	R:R:I450	7.36	No	No	0	7	7
639	R:R:S178	R:R:S181	6.52	No	No	0	9	8
640	R:R:F195	R:R:S178	5.28	Yes	No	0	8	9
641	R:R:V409	R:R:Y179	8.83	No	Yes	0	7	8
642	R:R:A180	R:R:K405	6.42	No	Yes	0	6	4
643	R:R:D202	R:R:T182	8.67	Yes	Yes	1	8	8
644	R:R:T182	R:R:Y230	3.75	Yes	Yes	1	8	7
645	R:R:D312	R:R:T182	5.78	Yes	Yes	1	8	8
646	R:R:P184	R:R:S201	5.34	No	No	0	5	8
647	R:R:D202	R:R:P184	6.44	Yes	No	0	8	5
648	R:R:P184	R:R:S233	5.34	No	No	0	5	4
649	R:R:F195	R:R:L186	21.92	Yes	Yes	40	8	8
650	R:R:L186	R:R:R197	6.07	Yes	No	0	8	9
651	R:R:N468	R:R:S187	4.47	Yes	No	41	7	8
652	R:R:D470	R:R:S187	8.83	Yes	No	41	7	8
653	R:R:D188	R:R:S190	8.83	No	No	0	6	2
654	R:R:D188	R:R:R191	8.34	No	No	0	6	5
655	R:R:D188	S:S:E259	9.09	No	No	0	6	3
656	R:R:N189	R:R:N468	4.09	No	Yes	0	7	7
657	R:R:R191	R:R:Y192	20.58	No	No	0	5	5
658	R:R:R191	S:S:R258	6.4	No	No	0	5	4
659	R:R:D193	R:R:F194	9.55	No	Yes	0	6	7
660	R:R:F194	R:R:L447	12.18	Yes	No	0	7	6
661	R:R:R451	R:R:S196	7.91	No	No	0	6	6
662	R:R:R197	R:R:S201	9.22	No	No	0	9	8
663	R:R:D470	R:R:R197	14.29	Yes	No	0	7	9
664	R:R:P200	R:R:V199	3.53	Yes	No	1	7	7
665	R:R:P336	R:R:V199	3.53	Yes	No	1	5	7
666	R:R:F408	R:R:V199	9.18	Yes	No	1	7	7
667	R:R:P200	R:R:Y204	5.56	Yes	No	0	7	4
668	R:R:P200	R:R:P336	7.79	Yes	Yes	1	7	5
669	R:R:A471	R:R:P200	5.61	No	Yes	0	4	7
670	R:R:G473	R:R:P200	4.06	No	Yes	0	5	7
671	R:R:P200	R:R:Y475	12.52	Yes	Yes	1	7	8
672	R:R:D202	R:R:Q205	10.44	Yes	Yes	1	8	9
673	R:R:D202	R:R:Y230	6.9	Yes	Yes	1	8	7
674	R:R:D202	R:R:G234	5.03	Yes	No	1	8	7
675	R:R:D202	R:R:F284	3.58	Yes	Yes	1	8	8
676	R:R:T203	R:R:Y204	8.74	No	No	0	3	4
677	R:R:D470	R:R:Y204	4.6	Yes	No	0	7	4
678	R:R:F284	R:R:Q205	7.03	Yes	Yes	1	8	9
679	R:R:D312	R:R:Q205	7.83	Yes	Yes	1	8	9
680	R:R:I334	R:R:Q205	4.12	No	Yes	1	7	9
681	R:R:Q205	R:R:Y475	9.02	Yes	Yes	1	9	8
682	R:R:D211	R:R:Q207	7.83	No	Yes	1	5	4
683	R:R:K241	R:R:Q207	12.2	No	Yes	1	5	4
684	R:R:E244	R:R:Q207	5.1	No	Yes	1	4	4
685	R:R:Q207	R:R:W495	5.48	Yes	Yes	1	4	5
686	R:R:A208	R:R:W495	10.37	No	Yes	0	7	5
687	R:R:F284	R:R:M209	3.73	Yes	No	0	8	7
688	R:R:D211	R:R:W495	7.82	No	Yes	1	5	5
689	R:R:I212	R:R:M309	4.37	No	No	0	8	6
690	R:R:V213	R:R:W218	3.68	No	Yes	0	6	9
691	R:R:V213	R:R:V248	4.81	No	No	0	6	7
692	R:R:N219	R:R:R214	4.82	No	No	0	6	4
693	R:R:L216	R:R:W218	12.53	No	Yes	0	8	9
694	R:R:A280	R:R:W218	5.19	No	Yes	0	8	9
695	R:R:F307	R:R:W218	6.01	Yes	Yes	15	7	9
696	R:R:W218	R:R:W508	5.62	Yes	Yes	15	9	8
697	R:R:P516	R:R:W218	6.76	Yes	Yes	15	8	9
698	R:R:S518	R:R:W218	11.12	No	Yes	0	9	9
699	R:R:I519	R:R:N219	4.25	No	No	0	5	6
700	R:R:A251	R:R:Y220	8.01	No	Yes	0	8	9
701	R:R:T275	R:R:Y220	3.75	No	Yes	0	3	9
702	R:R:C520	R:R:Y220	12.1	No	Yes	0	9	9
703	R:R:L272	R:R:S222	4.5	Yes	No	9	8	8
704	R:R:S222	R:R:V281	4.85	No	Yes	9	8	6
705	R:R:T223	R:R:V235	4.76	No	No	0	5	5
706	R:R:I250	R:R:T223	4.56	No	No	0	6	5
707	R:R:S253	R:R:T223	7.99	No	No	0	4	5
708	R:R:V224	R:R:V254	4.81	No	No	0	5	5
709	R:R:I283	R:R:V224	10.75	No	No	0	5	5
710	R:R:A225	R:R:V235	5.09	No	No	0	5	5
711	R:R:A225	R:R:K255	4.82	No	No	0	5	4
712	R:R:E227	R:R:R258	17.45	No	No	0	7	4
713	R:R:G228	R:R:R258	4.5	No	No	0	6	4
714	R:R:G231	R:R:Y230	4.35	No	Yes	0	8	7
715	R:R:F284	R:R:Y230	4.13	Yes	Yes	1	8	7
716	R:R:S311	R:R:Y230	5.09	No	Yes	1	8	7
717	R:R:S313	R:R:Y230	3.82	No	Yes	1	6	7
718	R:R:E232	R:R:K255	12.15	No	No	0	5	4
719	R:R:F284	R:R:G234	6.02	Yes	No	1	8	7
720	R:R:F284	R:R:V235	3.93	Yes	No	0	8	5
721	R:R:E236	S:S:K255	6.75	No	No	0	5	4
722	R:R:F238	R:R:I282	5.02	No	No	0	7	7
723	R:R:I239	R:R:R243	3.76	No	No	0	4	3
724	R:R:I239	R:R:I250	5.89	No	No	0	4	6
725	R:R:Q240	R:R:R243	11.68	No	No	0	4	3
726	R:R:E244	R:R:K241	4.05	No	No	1	4	5
727	R:R:R243	S:S:R271	15.99	No	No	0	3	3
728	R:R:C249	R:R:C538	7.28	No	No	0	9	9
729	R:R:L272	R:R:Q252	3.99	Yes	No	0	8	6
730	R:R:Q252	R:R:T275	5.67	No	No	0	6	3
731	R:R:I268	R:R:V254	4.61	No	No	0	5	5
732	R:R:R271	R:R:V254	6.54	No	No	0	3	5
733	R:R:F265	R:R:I256	3.77	Yes	No	18	4	5
734	R:R:D289	R:R:I256	11.2	Yes	No	18	4	5
735	R:R:E264	R:R:P257	9.43	Yes	No	0	3	4
736	R:R:R258	S:S:R191	9.6	No	Yes	0	4	5
737	R:R:E259	S:S:S190	4.31	No	No	0	3	2
738	R:R:E264	R:R:P260	4.72	Yes	No	0	3	2
739	R:R:F265	R:R:P260	4.33	Yes	No	0	4	2
740	R:R:E264	R:R:K261	4.05	Yes	No	0	3	3
741	R:R:D266	R:R:G263	5.03	No	No	0	3	1
742	R:R:E264	R:R:I268	8.2	Yes	No	0	3	5
743	R:R:D289	R:R:F265	4.78	Yes	Yes	18	4	4
744	R:R:F265	R:R:R292	17.1	Yes	Yes	18	4	1
745	R:R:F265	R:R:V293	3.93	Yes	No	0	4	5
746	R:R:D266	R:R:R299	5.96	No	No	0	3	3
747	R:R:K267	R:R:R270	8.66	No	No	0	2	1
748	R:R:R271	S:S:R243	17.06	No	No	0	3	3
749	R:R:L272	R:R:V281	4.47	Yes	Yes	9	8	6
750	R:R:F306	R:R:L272	9.74	Yes	Yes	9	7	8
751	R:R:L273	R:R:Q302	13.31	No	No	0	5	4
752	R:R:H305	R:R:S276	5.58	Yes	No	0	3	7
753	R:R:H305	R:R:R279	13.54	Yes	No	0	3	6
754	R:R:F307	R:R:R279	5.34	Yes	No	0	7	6
755	R:R:F306	R:R:V281	5.24	Yes	Yes	9	7	6
756	R:R:V281	R:R:W308	4.9	Yes	Yes	9	6	7
757	R:R:I282	R:R:M309	10.2	No	No	0	7	6
758	R:R:I283	R:R:I290	5.89	No	No	0	5	4
759	R:R:I283	R:R:W308	3.52	No	Yes	0	5	7
760	R:R:F284	R:R:S311	13.21	Yes	No	1	8	8
761	R:R:A285	R:R:D289	4.63	No	Yes	0	4	4
762	R:R:D288	R:R:N286	13.46	No	No	18	1	5
763	R:R:D289	R:R:N286	10.77	Yes	No	18	4	5
764	R:R:E287	R:R:K317	4.05	No	No	0	3	6
765	R:R:E287	R:R:P320	7.86	No	No	0	3	5
766	R:R:D288	R:R:D289	3.99	No	Yes	18	1	4
767	R:R:D288	R:R:R292	7.15	No	Yes	18	1	1
768	R:R:D289	R:R:R292	4.76	Yes	Yes	18	4	1
769	R:R:I290	R:R:W314	5.87	No	Yes	0	4	7
770	R:R:L294	R:R:W308	7.97	Yes	Yes	9	5	7
771	R:R:L294	R:R:L324	8.3	Yes	No	9	5	4
772	R:R:L294	R:R:V327	8.94	Yes	Yes	9	5	3
773	R:R:E295	R:R:R299	15.12	No	No	0	2	3
774	R:R:A296	R:R:R299	5.53	No	No	0	5	3
775	R:R:L324	R:R:R298	4.86	No	No	9	4	3
776	R:R:E326	R:R:R298	5.82	No	No	0	3	3
777	R:R:R298	R:R:V327	14.38	No	Yes	9	3	3
778	R:R:H305	R:R:Q302	14.84	Yes	No	9	3	4
779	R:R:F306	R:R:Q302	4.68	Yes	No	9	7	4
780	R:R:F306	R:R:H305	9.05	Yes	Yes	9	7	3
781	R:R:F306	R:R:W308	14.03	Yes	Yes	9	7	7
782	R:R:F307	R:R:W508	8.02	Yes	Yes	15	7	8
783	R:R:F307	R:R:P516	7.22	Yes	Yes	15	7	8
784	R:R:V327	R:R:W308	3.68	Yes	Yes	9	3	7
785	R:R:M309	R:R:V332	6.09	No	No	0	6	5
786	R:R:G310	R:R:W314	5.63	No	Yes	0	7	7
787	R:R:D312	R:R:P336	9.66	Yes	Yes	1	8	5
788	R:R:D312	R:R:Y475	4.6	Yes	Yes	1	8	8
789	R:R:S313	R:R:W314	6.18	No	Yes	1	6	7
790	R:R:P320	R:R:W314	5.4	No	Yes	0	5	7
791	R:R:V321	R:R:W314	3.68	No	Yes	1	4	7
792	R:R:T333	R:R:W314	3.64	No	Yes	0	7	7
793	R:R:W314	R:R:Y489	5.79	Yes	Yes	1	7	5
794	R:R:G315	R:R:L335	5.13	No	No	0	5	5
795	R:R:S316	R:R:Y489	6.36	No	Yes	0	5	5
796	R:R:E403	R:R:K317	10.8	Yes	No	0	5	6
797	R:R:V321	R:R:Y480	8.83	No	No	1	4	6
798	R:R:V321	R:R:Y489	5.05	No	Yes	1	4	5
799	R:R:H323	R:R:L322	9	No	No	0	1	3
800	R:R:L324	R:R:V327	4.47	No	Yes	9	4	3
801	R:R:E325	R:R:Y480	4.49	No	No	0	4	6
802	R:R:E329	R:R:L482	9.28	No	No	0	5	3
803	R:R:G330	R:R:Q479	4.93	No	Yes	0	8	8
804	R:R:I334	R:R:Y475	8.46	No	Yes	1	7	8
805	R:R:L335	R:R:P336	4.93	No	Yes	0	5	5
806	R:R:L335	R:R:Y478	7.03	No	No	0	5	4
807	R:R:F408	R:R:P336	7.22	Yes	Yes	1	7	5
808	R:R:P336	R:R:Y475	9.74	Yes	Yes	1	5	8
809	R:R:K337	R:R:R474	12.38	No	No	0	5	4
810	R:R:D476	R:R:K337	15.21	No	No	0	8	5
811	R:R:G404	R:R:R338	6	No	No	0	5	5
812	R:R:G343	R:R:R346	4.5	No	No	0	5	3
813	R:R:F344	R:R:Q402	9.37	No	Yes	28	8	6
814	R:R:F344	R:R:V406	14.42	No	No	28	8	6
815	R:R:D345	R:R:Y400	8.05	No	Yes	0	4	5
816	R:R:D345	R:R:Q402	6.53	No	Yes	0	4	6
817	R:R:R351	R:R:Y347	20.58	Yes	No	1	5	7
818	R:R:F348	R:R:F365	4.29	Yes	Yes	1	7	6
819	R:R:F348	R:R:I394	11.3	Yes	Yes	1	7	5
820	R:R:F348	R:R:Y400	6.19	Yes	Yes	1	7	5
821	R:R:N355	R:R:R351	4.82	No	Yes	0	4	5
822	R:R:N356	R:R:R351	14.46	No	Yes	1	4	5
823	R:R:N355	R:R:T352	8.77	No	No	0	4	4
824	R:R:R393	R:R:T352	3.88	No	No	0	4	4
825	R:R:L353	R:R:W366	17.08	No	No	0	6	6
826	R:R:D354	R:R:R357	4.76	No	No	0	4	3
827	R:R:F362	R:R:N356	12.08	Yes	No	1	5	4
828	R:R:N359	R:R:W361	6.78	Yes	Yes	1	7	5
829	R:R:F362	R:R:N359	4.83	Yes	Yes	1	5	7
830	R:R:I360	R:R:W361	9.4	No	Yes	0	3	5
831	R:R:F362	R:R:F365	8.57	Yes	Yes	1	5	6
832	R:R:F365	R:R:N369	15.71	Yes	Yes	1	6	3
833	R:R:F365	R:R:I394	3.77	Yes	Yes	1	6	5
834	R:R:F370	R:R:W366	18.04	Yes	No	0	8	6
835	R:R:E367	R:R:K373	12.15	No	No	0	6	4
836	R:R:F370	R:R:N369	7.25	Yes	Yes	1	8	3
837	R:R:D397	R:R:N369	6.73	No	Yes	1	3	3
838	R:R:E392	R:R:F370	16.32	No	Yes	0	7	8
839	R:R:F370	R:R:I394	3.77	Yes	Yes	1	8	5
840	R:R:D397	R:R:F370	8.36	No	Yes	1	3	8
841	R:R:C372	R:R:C388	5.46	No	No	0	8	8
842	R:R:K387	R:R:V385	4.55	No	No	0	1	1
843	R:R:R391	R:R:T389	23.29	No	No	0	3	6
844	R:R:E392	R:R:Q396	6.37	No	No	0	7	1
845	R:R:I394	R:R:Y400	3.63	Yes	Yes	1	5	5
846	R:R:Q402	R:R:V406	4.3	Yes	No	28	6	6
847	R:R:F408	R:R:K405	6.2	Yes	Yes	1	7	4
848	R:R:D411	R:R:Q407	11.75	No	Yes	0	8	7
849	R:R:A459	R:R:Q407	6.06	No	Yes	42	4	7
850	R:R:N461	R:R:Q407	3.96	Yes	Yes	42	5	7
851	R:R:I410	R:R:Y414	3.63	No	No	0	7	8
852	R:R:D411	R:R:V463	5.84	No	No	0	8	6
853	R:R:F455	R:R:H418	13.58	Yes	No	0	9	6
854	R:R:L420	R:R:L446	4.15	No	No	0	8	6
855	R:R:H421	R:R:R425	6.77	No	No	0	7	3
856	R:R:L427	R:R:M423	4.24	No	No	0	3	6
857	R:R:M423	R:R:M438	4.33	No	No	0	6	4
858	R:R:M423	R:R:Y449	9.58	No	Yes	0	6	4
859	R:R:C428	R:R:H424	7.37	Yes	Yes	44	7	5
860	R:R:C435	R:R:H424	4.42	No	Yes	44	6	5
861	R:R:H424	R:R:M438	3.94	Yes	No	0	5	4
862	R:R:D426	R:R:Y449	10.34	No	Yes	0	4	4
863	R:R:L427	R:R:R437	4.86	No	No	0	3	3
864	R:R:L427	R:R:Q445	3.99	No	Yes	0	3	6
865	R:R:C428	R:R:C435	7.28	Yes	No	44	7	6
866	R:R:C428	R:R:R437	4.18	Yes	No	0	7	3
867	R:R:D442	R:R:Q445	6.53	No	Yes	0	4	6
868	R:R:K448	R:R:Q445	4.07	No	Yes	43	3	6
869	R:R:Q445	R:R:Y449	6.76	Yes	Yes	43	6	4
870	R:R:L447	R:R:R451	4.86	No	No	0	6	6
871	R:R:K448	R:R:Y449	14.33	No	Yes	43	3	4
872	R:R:K448	R:R:N452	8.39	No	No	0	3	4
873	R:R:G469	R:R:R451	4.5	No	No	0	7	6
874	R:R:F455	R:R:V453	5.24	Yes	No	0	9	7
875	R:R:F465	R:R:V453	5.24	No	No	0	8	7
876	R:R:N454	R:R:T464	5.85	No	No	0	5	3
877	R:R:F455	R:R:V463	6.55	Yes	No	0	9	6
878	R:R:A459	R:R:N461	4.69	No	Yes	42	4	5
879	R:R:N461	R:R:R474	6.03	Yes	No	0	5	4
880	R:R:N466	R:R:N468	4.09	No	Yes	0	7	7
881	R:R:D470	R:R:N468	14.81	Yes	Yes	41	7	7
882	R:R:W495	R:R:Y475	6.75	Yes	Yes	1	5	8
883	R:R:D476	R:R:Y478	9.2	No	No	0	8	4
884	R:R:I477	R:R:I492	4.42	No	Yes	0	7	7
885	R:R:G493	R:R:I477	3.53	No	No	0	9	7
886	R:R:I477	R:R:L501	4.28	No	No	0	7	7
887	R:R:V491	R:R:Y478	7.57	No	No	0	5	4
888	R:R:Q479	R:R:Q481	10.24	Yes	No	0	8	7
889	R:R:I492	R:R:Q479	8.23	Yes	Yes	15	7	8
890	R:R:M506	R:R:Q479	6.8	No	Yes	15	7	8
891	R:R:Q479	R:R:W508	14.24	Yes	Yes	15	8	8
892	R:R:Y480	R:R:Y489	18.86	No	Yes	1	6	5
893	R:R:K490	R:R:Q481	4.07	No	No	0	5	7
894	R:R:H507	R:R:Q481	4.95	No	No	0	4	7
895	R:R:E488	R:R:R483	9.3	No	No	0	4	3
896	R:R:I492	R:R:M506	7.29	Yes	No	15	7	7
897	R:R:H500	R:R:S494	6.97	No	No	0	1	3
898	R:R:H498	R:R:H500	13.14	No	No	0	4	1
899	R:R:L499	R:R:L501	4.15	No	No	45	7	7
900	R:R:E504	R:R:R502	15.12	No	No	0	3	5
901	R:R:R502	R:R:R505	29.85	No	No	0	5	3
902	R:R:P516	R:R:W508	16.21	Yes	Yes	15	8	8
903	R:R:I519	R:R:R517	8.77	No	No	0	5	1
904	R:R:C520	R:R:C539	7.28	No	No	0	9	9
905	R:R:C539	R:R:S521	5.16	No	No	0	9	8
906	R:R:C524	R:R:R529	5.57	No	Yes	46	9	6
907	R:R:C524	R:R:C542	5.46	No	No	46	9	9
908	R:R:E528	R:R:P526	4.72	No	No	0	5	6
909	R:R:E528	R:R:R529	9.3	No	Yes	0	5	6
910	R:R:E528	R:R:R570	10.47	No	No	0	5	6
911	R:R:C542	R:R:R529	9.75	No	Yes	46	9	6
912	R:R:P544	R:R:R529	15.85	No	Yes	0	4	6
913	R:R:E543	R:R:K530	6.75	No	No	0	4	8
914	R:R:K530	R:R:T556	4.5	No	No	0	8	4
915	R:R:K531	R:R:W540	40.61	No	No	0	6	8
916	R:R:H541	R:R:T532	4.11	No	No	0	6	3
917	R:R:K534	S:S:K534	11.49	No	No	0	6	6
918	R:R:C538	R:R:C539	3.64	No	No	0	9	9
919	R:R:E543	R:R:P544	6.29	No	No	0	4	4
920	R:R:E543	S:S:E543	6.34	No	No	0	4	4
921	R:R:C545	R:R:Q549	4.58	No	No	0	9	7
922	R:R:C545	R:R:C557	7.28	No	No	0	9	9
923	R:R:G547	R:R:T546	3.64	No	No	0	5	5
924	R:R:Q549	R:R:T546	8.5	No	No	0	7	5
925	R:R:Q549	R:R:Y548	5.64	No	No	0	7	8
926	R:R:T559	R:R:Y548	14.98	No	No	0	3	8
927	R:R:L735	R:R:Y548	5.86	Yes	No	0	6	8
928	R:R:P566	R:R:Y550	20.86	No	Yes	0	8	7
929	R:R:R570	R:R:Y550	29.84	No	Yes	0	6	7
930	R:R:D553	R:R:V552	8.76	No	No	0	7	6
931	R:R:K558	R:R:V552	7.59	No	No	0	1	6
932	R:R:C560	R:R:P561	3.77	No	No	0	9	4
933	R:R:C560	R:R:C573	7.28	No	No	0	9	9
934	R:R:M564	R:R:P561	10.06	Yes	No	0	5	4
935	R:R:Q730	R:R:Y562	10.15	No	No	0	3	3
936	R:R:R733	R:R:Y562	7.2	No	No	0	6	3
937	R:R:D563	R:R:M564	5.54	Yes	Yes	22	6	5
938	R:R:D563	R:R:P575	9.66	Yes	No	22	6	3
939	R:R:D563	R:R:D728	3.99	Yes	No	22	6	6
940	R:R:D563	R:R:Q730	5.22	Yes	No	22	6	3
941	R:R:C573	R:R:M564	4.86	No	Yes	0	9	5
942	R:R:M564	R:R:P575	15.09	Yes	No	22	5	3
943	R:R:I576	R:R:R565	7.52	No	No	0	8	7
944	R:R:R565	R:R:R741	29.85	No	Yes	0	7	5
945	R:R:R574	R:R:T567	9.06	No	No	0	4	7
946	R:R:E568	R:R:F739	4.66	No	No	0	1	3
947	R:R:E582	R:R:I579	12.3	No	No	0	6	5
948	R:R:K580	R:R:L815	7.05	Yes	No	0	6	6
949	R:R:L581	R:R:Y816	11.72	No	No	0	8	5
950	R:R:I644	R:R:W583	4.7	Yes	No	0	8	5
951	R:R:I817	R:R:W587	5.87	No	No	0	5	5
952	R:R:P591	R:R:V824	5.3	Yes	No	0	8	7
953	R:R:I644	R:R:L592	8.56	Yes	No	0	8	6
954	R:R:A595	R:R:T640	5.03	No	No	0	7	7
955	R:R:A595	R:R:F641	4.16	No	No	0	7	7
956	R:R:G598	R:R:Y637	10.14	No	Yes	0	7	8
957	R:R:F634	R:R:I599	8.79	No	No	0	4	6
958	R:R:I599	R:R:Y637	6.04	No	Yes	0	6	8
959	R:R:T602	R:R:Y637	4.99	No	Yes	0	7	8
960	R:R:L834	R:R:T602	7.37	No	No	0	8	7
961	R:R:F604	R:R:L846	4.87	No	Yes	0	4	6
962	R:R:L630	R:R:V605	5.96	No	No	12	9	6
963	R:R:V605	R:R:Y838	3.79	No	Yes	12	6	9
964	R:R:L630	R:R:V606	4.47	No	No	0	9	5
965	R:R:F609	R:R:T608	5.19	No	No	12	8	6
966	R:R:T608	R:R:V842	12.69	No	No	12	6	8
967	R:R:L846	R:R:T608	4.42	Yes	No	12	6	6
968	R:R:F609	R:R:S626	5.28	No	No	12	8	8
969	R:R:F609	R:R:Y838	9.28	No	Yes	12	8	9
970	R:R:V610	R:R:Y627	3.79	No	No	0	4	7
971	R:R:R611	R:R:Y612	12.35	No	No	0	4	5
972	R:R:T615	R:R:Y612	4.99	Yes	No	0	9	5
973	R:R:I845	R:R:Y612	4.84	No	No	0	8	5
974	R:R:N613	R:R:R623	9.64	No	No	0	6	8
975	R:R:N613	R:R:Y627	4.65	No	No	0	6	7
976	R:R:D614	R:R:T615	4.34	No	Yes	0	5	9
977	R:R:I617	R:R:T615	4.56	No	Yes	0	7	9
978	R:R:N852	R:R:T615	10.24	No	Yes	0	9	9
979	R:R:K619	R:R:R623	8.66	No	No	0	7	8
980	R:R:A620	R:R:F781	5.55	No	Yes	0	9	9
981	R:R:K841	R:R:S621	7.65	Yes	No	0	9	9
982	R:R:E624	R:R:R623	4.65	No	No	0	6	8
983	R:R:E624	R:R:R676	9.3	No	Yes	0	6	8
984	R:R:E624	R:R:P696	14.15	No	No	0	6	6
985	R:R:L625	R:R:T672	4.42	No	Yes	6	8	7
986	R:R:K673	R:R:L625	7.05	No	No	0	9	8
987	R:R:L625	R:R:T703	4.42	No	Yes	6	8	7
988	R:R:S626	R:R:Y838	5.09	No	Yes	12	8	9
989	R:R:L629	R:R:Y838	8.21	No	Yes	0	8	9
990	R:R:L630	R:R:Y838	5.86	No	Yes	12	9	9
991	R:R:I633	R:R:Y637	4.84	Yes	Yes	0	9	8
992	R:R:I633	R:R:S666	4.64	Yes	No	0	9	7
993	R:R:I633	R:R:L834	8.56	Yes	No	0	9	8
994	R:R:F658	R:R:L635	6.09	Yes	No	0	6	6
995	R:R:S831	R:R:Y637	7.63	No	Yes	0	5	8
996	R:R:F658	R:R:T639	3.89	Yes	No	0	6	7
997	R:R:L659	R:R:T639	4.42	No	No	0	8	7
998	R:R:T640	R:R:T823	9.42	No	No	0	7	7
999	R:R:S827	R:R:T640	4.8	No	No	0	9	7
1000	R:R:L642	R:R:L654	13.84	No	No	48	5	5
1001	R:R:F658	R:R:L642	4.87	Yes	No	48	6	5
1002	R:R:M643	R:R:R655	6.2	No	Yes	0	7	8
1003	R:R:P647	R:R:R655	7.21	Yes	Yes	0	9	8
1004	R:R:L744	R:R:P647	6.57	No	Yes	0	7	9
1005	R:R:D648	R:R:T651	4.34	No	No	0	5	6
1006	R:R:R655	R:R:T651	7.76	Yes	No	0	8	6
1007	R:R:C652	R:R:S725	5.16	No	No	0	9	5
1008	R:R:C652	R:R:C746	7.28	No	No	0	9	9
1009	R:R:F718	R:R:S653	5.28	No	No	0	7	5
1010	R:R:F658	R:R:L654	12.18	Yes	No	48	6	5
1011	R:R:C746	R:R:R655	5.57	No	Yes	0	9	8
1012	R:R:R656	R:R:W717	5	No	No	0	8	8
1013	R:R:R656	R:R:S752	9.22	No	No	0	8	6
1014	R:R:M663	R:R:V826	6.09	No	No	0	8	8
1015	R:R:Q710	R:R:S664	10.11	No	No	49	9	7
1016	R:R:S664	R:R:Y759	5.09	No	Yes	49	7	8
1017	R:R:I665	R:R:I707	7.36	No	No	0	7	7
1018	R:R:M764	R:R:Y667	3.59	No	Yes	0	8	6
1019	R:R:M791	R:R:Y667	5.99	No	Yes	0	9	6
1020	R:R:T794	R:R:Y667	11.24	No	Yes	0	8	6
1021	R:R:S833	R:R:Y667	5.09	No	Yes	0	7	6
1022	R:R:I787	R:R:L670	11.42	Yes	No	0	9	7
1023	R:R:L671	R:R:T766	7.37	No	No	0	8	4
1024	R:R:C767	R:R:L671	6.35	No	No	0	8	8
1025	R:R:L671	R:R:Y770	4.69	No	No	0	8	7
1026	R:R:Q699	R:R:T672	4.25	No	Yes	6	8	7
1027	R:R:I702	R:R:T672	4.56	No	Yes	0	6	7
1028	R:R:T672	R:R:T703	6.28	Yes	Yes	6	7	7
1029	R:R:K673	R:R:R676	3.71	No	Yes	0	9	8
1030	R:R:T674	R:R:Y770	3.75	No	No	0	9	7
1031	R:R:N675	R:R:R679	16.87	No	Yes	0	6	7
1032	R:R:N675	R:R:Y770	20.93	No	No	0	6	7
1033	R:R:R676	R:R:R679	4.26	Yes	Yes	6	8	7
1034	R:R:I680	R:R:R676	3.76	Yes	Yes	6	9	8
1035	R:R:I694	R:R:R676	3.76	Yes	Yes	6	7	8
1036	R:R:Q699	R:R:R676	23.36	No	Yes	6	8	8
1037	R:R:F681	R:R:I677	3.77	Yes	No	0	9	9
1038	R:R:K773	R:R:Y678	8.36	No	No	0	7	6
1039	R:R:T774	R:R:Y678	8.74	No	No	0	8	6
1040	R:R:P691	R:R:R679	5.76	Yes	Yes	6	7	7
1041	R:R:I694	R:R:R679	5.01	Yes	Yes	6	7	7
1042	R:R:Q699	R:R:R679	7.01	No	Yes	6	8	7
1043	R:R:F681	R:R:I680	5.02	Yes	Yes	6	9	9
1044	R:R:I680	R:R:I694	5.89	Yes	Yes	6	9	7
1045	R:R:F681	R:R:V777	13.11	Yes	Yes	6	9	8
1046	R:R:F681	R:R:P778	4.33	Yes	No	6	9	9
1047	R:R:F681	R:R:F781	7.5	Yes	Yes	6	9	9
1048	R:R:E682	R:R:K685	8.1	No	No	0	6	5
1049	R:R:E682	R:R:R686	8.14	No	No	0	6	6
1050	R:R:G684	R:R:Q683	4.93	No	Yes	0	7	5
1051	R:R:Q683	R:R:S687	7.22	Yes	No	0	5	4
1052	R:R:P691	R:R:Q683	15.79	Yes	Yes	0	7	5
1053	R:R:I694	R:R:P691	5.08	Yes	Yes	6	7	7
1054	R:R:F693	R:R:S698	7.93	No	No	0	5	7
1055	R:R:L709	R:R:Y759	5.86	No	Yes	0	5	8
1056	R:R:Q710	R:R:Y759	9.02	No	Yes	49	9	8
1057	R:R:G713	R:R:V716	3.68	No	No	0	7	4
1058	R:R:F718	R:R:S723	3.96	No	No	0	7	8
1059	R:R:D721	R:R:P722	4.83	Yes	No	0	6	7
1060	R:R:D721	R:R:H724	8.82	Yes	No	50	6	4
1061	R:R:D721	R:R:D747	5.32	Yes	No	50	6	5
1062	R:R:D747	R:R:H724	21.43	No	No	50	5	4
1063	R:R:D728	R:R:V726	4.38	No	No	0	6	3
1064	R:R:L744	R:R:V727	4.47	No	No	0	7	4
1065	R:R:D728	R:R:Q730	5.22	No	No	22	6	3
1066	R:R:F729	R:R:V743	11.8	No	Yes	0	4	6
1067	R:R:F729	R:R:K745	29.78	No	No	0	4	7
1068	R:R:Q732	R:R:V743	7.16	No	Yes	0	6	6
1069	R:R:L735	R:R:R733	7.29	Yes	No	47	6	6
1070	R:R:R733	R:R:R741	13.86	No	Yes	47	6	5
1071	R:R:L735	R:R:R741	8.5	Yes	Yes	47	6	5
1072	R:R:D736	S:S:L735	6.79	No	No	0	3	6
1073	R:R:G742	R:R:R741	4.5	No	Yes	0	7	5
1074	R:R:I748	R:R:L753	8.56	No	No	0	5	7
1075	R:R:S749	R:R:S752	4.89	No	No	0	8	6
1076	R:R:D750	R:R:F805	4.78	No	Yes	0	3	8
1077	R:R:F805	R:R:L753	3.65	Yes	No	0	8	7
1078	R:R:L753	R:R:L822	4.15	No	No	0	7	8
1079	R:R:F806	R:R:I754	6.28	No	No	0	6	5
1080	R:R:L757	R:R:W798	12.53	No	No	51	8	9
1081	R:R:F801	R:R:L757	3.65	Yes	No	51	9	8
1082	R:R:L763	R:R:Y759	10.55	No	Yes	0	9	8
1083	R:R:L762	R:R:T766	4.42	No	No	0	4	4
1084	R:R:C767	R:R:M791	4.86	No	No	0	8	9
1085	R:R:M791	R:R:T768	4.52	No	No	0	9	8
1086	R:R:T774	R:R:V777	4.76	No	Yes	0	8	8
1087	R:R:R775	S:S:Y843	11.32	No	No	0	9	8
1088	R:R:P778	R:R:V777	5.3	No	Yes	6	9	8
1089	R:R:F781	R:R:V777	3.93	Yes	Yes	6	9	8
1090	R:R:E779	R:R:T780	5.64	No	No	0	8	7
1091	R:R:F781	R:R:T780	7.78	Yes	No	0	9	7
1092	R:R:E783	R:R:I787	6.83	No	Yes	0	9	9
1093	R:R:E783	R:R:L837	3.98	No	No	0	9	8
1094	R:R:E783	R:R:K841	4.05	No	Yes	0	9	9
1095	R:R:K785	S:S:K785	4.31	No	No	0	9	9
1096	R:R:F789	S:S:F789	13.93	No	No	5	9	9
1097	R:R:F789	S:S:T793	3.89	No	Yes	5	9	8
1098	R:R:F789	S:S:M836	6.22	No	No	5	9	7
1099	R:R:M836	R:R:T790	6.02	No	No	0	7	9
1100	R:R:I796	R:R:Y792	13.3	No	Yes	5	8	9
1101	R:R:Y792	S:S:T793	3.75	Yes	Yes	5	9	8
1102	R:R:Y792	S:S:V797	3.79	Yes	No	5	9	8
1103	R:R:Y792	S:S:L828	5.86	Yes	No	5	9	6
1104	R:R:Y792	S:S:V832	5.05	Yes	No	5	9	7
1105	R:R:T793	R:R:V832	7.93	No	No	0	8	7
1106	R:R:T793	S:S:I796	4.56	No	No	0	8	8
1107	R:R:S829	R:R:T794	6.4	No	No	0	9	8
1108	R:R:I796	S:S:V797	4.61	No	No	5	8	8
1109	R:R:I796	S:S:L828	4.28	No	No	5	8	6
1110	R:R:F801	R:R:W798	11.02	Yes	No	51	9	9
1111	R:R:L799	X:X:?1	7.22	No	Yes	0	6	0
1112	R:R:F801	R:R:I802	3.77	Yes	No	0	9	7
1113	R:R:F801	R:R:F805	20.36	Yes	Yes	0	9	8
1114	R:R:F801	R:R:T821	3.89	Yes	No	0	9	8
1115	R:R:F801	R:R:L822	8.53	Yes	No	0	9	8
1116	R:R:F801	R:R:S825	7.93	Yes	No	0	9	8
1117	R:R:I802	X:X:?1	5.32	No	Yes	0	7	0
1118	R:R:P803	X:X:?1	17.14	No	Yes	0	9	0
1119	R:R:I804	R:R:T821	13.68	No	No	0	7	8
1120	R:R:F805	R:R:F806	7.5	Yes	No	0	8	6
1121	R:R:F805	R:R:Q818	28.11	Yes	No	0	8	6
1122	R:R:I817	R:R:T808	10.64	No	No	0	5	8
1123	R:R:D813	R:R:Y816	13.79	No	No	0	4	5
1124	R:R:K814	R:R:Q818	8.14	No	No	0	6	6
1125	R:R:M836	R:R:V832	4.56	No	No	0	7	7
1126	R:R:K841	R:R:Y838	4.78	Yes	Yes	0	9	9
1127	R:R:L846	R:R:V842	4.47	Yes	No	12	6	8
1128	R:R:F847	R:R:Y843	9.28	No	No	0	5	8
1129	R:R:H848	R:R:Y843	10.89	No	No	0	7	8
1130	R:R:I844	R:R:Q851	6.86	No	No	0	8	4
1131	R:R:I845	R:R:N852	12.74	No	No	0	8	9
1132	R:R:F847	R:R:L846	4.87	No	Yes	0	5	6
1133	R:R:E850	R:R:H848	3.69	No	No	0	6	7
1134	S:S:I360	S:S:N41	4.25	No	No	0	3	5
1135	S:S:R44	S:S:S42	5.27	No	No	0	4	3
1136	S:S:I43	S:S:N359	4.25	No	Yes	4	4	7
1137	S:S:I43	S:S:W361	5.87	No	Yes	4	4	5
1138	S:S:R104	S:S:R44	17.06	No	No	0	5	4
1139	S:S:G102	S:S:I45	3.53	No	No	0	9	4
1140	S:S:A103	S:S:I45	4.87	No	No	0	7	4
1141	S:S:I45	S:S:R358	3.76	No	Yes	0	4	4
1142	S:S:D48	S:S:I99	5.6	No	Yes	0	8	5
1143	S:S:D48	S:S:L434	10.86	No	No	0	8	3
1144	S:S:I49	S:S:I99	4.42	No	Yes	0	6	5
1145	S:S:I49	S:S:V151	4.61	No	Yes	0	6	4
1146	S:S:G102	S:S:T50	3.64	No	No	0	9	4
1147	S:S:L101	S:S:L51	4.15	Yes	No	0	9	7
1148	S:S:L51	S:S:M416	4.24	No	Yes	0	7	6
1149	S:S:L54	S:S:T108	4.42	No	No	0	6	6
1150	S:S:F122	S:S:L54	4.87	Yes	No	0	5	6
1151	S:S:L54	S:S:V165	4.47	No	No	0	6	5
1152	S:S:F55	S:S:L79	7.31	Yes	No	3	9	5
1153	S:S:F55	S:S:M82	4.98	Yes	Yes	3	9	8
1154	S:S:F55	S:S:I105	6.28	Yes	No	3	9	8
1155	S:S:F55	S:S:Y179	10.32	Yes	Yes	3	9	8
1156	S:S:K71	S:S:P56	10.04	No	No	0	5	5
1157	S:S:G75	S:S:P56	4.06	No	No	0	5	5
1158	S:S:P56	S:S:S157	7.13	No	Yes	0	5	5
1159	S:S:H58	S:S:V57	6.92	Yes	No	4	8	6
1160	S:S:D107	S:S:V57	10.22	Yes	No	4	9	6
1161	S:S:V57	S:S:W361	18.39	No	Yes	4	6	5
1162	S:S:D107	S:S:H58	8.82	Yes	Yes	4	9	8
1163	S:S:C109	S:S:H58	4.42	Yes	Yes	4	7	8
1164	S:S:H58	S:S:W361	4.23	Yes	Yes	4	8	5
1165	S:S:E364	S:S:H58	3.69	Yes	Yes	4	5	8
1166	S:S:G59	S:S:S110	3.71	No	No	0	3	4
1167	S:S:R60	S:S:S110	3.95	No	No	0	2	4
1168	S:S:R111	S:S:R60	11.73	No	No	0	5	2
1169	S:S:N286	S:S:R60	3.62	No	No	0	5	2
1170	S:S:K65	S:S:P66	6.69	No	No	0	1	1
1171	S:S:C109	S:S:P66	3.77	Yes	No	0	7	1
1172	S:S:P66	S:S:R111	7.21	No	No	0	1	5
1173	S:S:E364	S:S:L70	5.3	Yes	No	0	5	5
1174	S:S:D368	S:S:L70	5.43	No	No	0	3	5
1175	S:S:K71	S:S:K74	10.06	No	Yes	0	5	5
1176	S:S:F365	S:S:K72	7.44	No	No	0	6	4
1177	S:S:D368	S:S:K72	13.83	No	No	0	3	4
1178	S:S:A319	S:S:E73	6.03	No	No	0	1	2
1179	S:S:K74	S:S:R78	14.85	Yes	Yes	3	5	4
1180	S:S:E287	S:S:K74	13.5	Yes	Yes	0	3	5
1181	S:S:E403	S:S:K74	8.1	Yes	Yes	3	5	5
1182	S:S:F365	S:S:I76	15.07	No	No	0	6	5
1183	S:S:R78	S:S:S157	3.95	Yes	Yes	3	4	5
1184	S:S:R78	S:S:Y179	9.26	Yes	Yes	3	4	8
1185	S:S:A180	S:S:R78	4.15	No	Yes	3	6	4
1186	S:S:E403	S:S:R78	13.96	Yes	Yes	3	5	4
1187	S:S:K405	S:S:R78	9.9	Yes	Yes	3	4	4
1188	S:S:R78	S:S:V409	3.92	Yes	No	3	4	7
1189	S:S:I105	S:S:L79	8.56	No	No	3	8	5
1190	S:S:E80	S:S:F348	7	No	No	0	8	7
1191	S:S:E80	S:S:N359	7.89	No	Yes	4	8	7
1192	S:S:E80	S:S:F362	7	No	Yes	4	8	5
1193	S:S:A81	S:S:F344	4.16	No	Yes	0	7	8
1194	S:S:L86	S:S:M82	4.24	No	Yes	0	7	8
1195	S:S:I105	S:S:M82	5.83	No	Yes	3	8	8
1196	S:S:I154	S:S:M82	4.37	No	Yes	0	8	8
1197	S:S:L83	S:S:R358	7.29	No	Yes	0	5	4
1198	S:S:F84	S:S:G343	4.52	No	No	0	7	5
1199	S:S:F84	S:S:Y347	15.47	No	No	0	7	7
1200	S:S:A85	S:S:I410	4.87	No	No	0	8	7
1201	S:S:A85	S:S:V413	5.09	No	No	0	8	9
1202	S:S:L101	S:S:L86	4.15	Yes	No	0	9	7
1203	S:S:D87	S:S:R358	10.72	No	Yes	0	7	4
1204	S:S:R88	S:S:Y414	9.26	No	No	0	8	8
1205	S:S:I89	S:S:L101	7.14	No	Yes	0	9	9
1206	S:S:I89	S:S:Y414	3.63	No	No	0	9	8
1207	S:S:N90	S:S:T100	8.77	No	No	0	9	7
1208	S:S:L101	S:S:N90	8.24	Yes	No	0	9	9
1209	S:S:D92	S:S:P93	6.44	No	No	0	7	3
1210	S:S:D92	S:S:L95	6.79	No	No	0	7	7
1211	S:S:H418	S:S:L95	6.43	No	No	0	6	7
1212	S:S:I99	S:S:L96	11.42	Yes	No	0	5	9
1213	S:S:L101	S:S:L96	4.15	Yes	No	0	9	9
1214	S:S:L420	S:S:L96	6.92	No	No	0	8	9
1215	S:S:H421	S:S:P97	6.1	No	No	0	7	8
1216	S:S:N98	S:S:V432	4.43	No	No	0	8	3
1217	S:S:H424	S:S:I99	3.98	No	Yes	0	5	5
1218	S:S:F122	S:S:R104	4.28	Yes	No	0	5	5
1219	S:S:L106	S:S:Q118	17.3	No	No	0	5	5
1220	S:S:F122	S:S:L106	7.31	Yes	No	0	5	5
1221	S:S:C109	S:S:D107	6.22	Yes	Yes	4	7	9
1222	S:S:D107	S:S:W361	4.47	Yes	Yes	4	9	5
1223	S:S:T108	S:S:V161	4.76	No	Yes	0	6	4
1224	S:S:C109	S:S:H114	7.37	Yes	No	0	7	3
1225	S:S:D112	S:S:V161	5.84	No	Yes	0	4	4
1226	S:S:D112	S:S:M164	19.41	No	Yes	0	4	5
1227	S:S:E117	S:S:H114	3.69	No	No	0	4	3
1228	S:S:H114	S:S:Q118	12.36	No	No	0	3	5
1229	S:S:A115	S:S:V161	5.09	No	Yes	0	7	4
1230	S:S:L116	S:S:M164	4.24	Yes	Yes	2	5	5
1231	S:S:I168	S:S:S119	4.64	Yes	No	0	5	6
1232	S:S:L169	S:S:S119	4.5	No	No	0	6	6
1233	S:S:F122	S:S:V153	3.93	Yes	No	0	5	6
1234	S:S:F172	S:S:V123	18.35	No	No	0	6	5
1235	S:S:R149	S:S:V151	5.23	No	Yes	53	3	4
1236	S:S:R149	S:S:V441	9.15	No	No	53	3	3
1237	S:S:L420	S:S:V151	4.47	No	Yes	0	8	4
1238	S:S:V151	S:S:V441	6.41	Yes	No	53	4	3
1239	S:S:G155	S:S:Q176	4.93	No	Yes	0	8	8
1240	S:S:G155	S:S:S178	3.71	No	No	0	8	9
1241	S:S:G158	S:S:S157	3.71	No	Yes	0	4	5
1242	S:S:S157	S:S:Y179	3.82	Yes	Yes	3	5	8
1243	S:S:S159	S:S:S181	4.89	No	No	0	9	8
1244	S:S:S159	S:S:Y230	5.09	No	Yes	3	9	7
1245	S:S:Q176	S:S:S162	4.33	Yes	No	2	8	7
1246	S:S:S162	S:S:S181	6.52	No	No	0	7	8
1247	S:S:F195	S:S:S162	6.61	Yes	No	2	8	7
1248	S:S:D185	S:S:I163	4.2	Yes	No	2	4	6
1249	S:S:I163	S:S:L186	5.71	No	Yes	2	6	8
1250	S:S:I163	S:S:Y192	10.88	No	Yes	2	6	5
1251	S:S:M164	S:S:N167	4.21	Yes	Yes	2	5	5
1252	S:S:Q176	S:S:V165	7.16	Yes	No	0	8	5
1253	S:S:A166	S:S:Q176	4.55	No	Yes	0	7	8
1254	S:S:A166	S:S:Y192	4	No	Yes	0	7	5
1255	S:S:I168	S:S:N167	4.25	Yes	Yes	2	5	5
1256	S:S:N167	S:S:Y192	4.65	Yes	Yes	2	5	5
1257	S:S:I174	S:S:L169	11.42	No	No	0	6	6
1258	S:S:L171	S:S:R170	3.64	No	Yes	0	5	5
1259	S:S:D193	S:S:R170	4.76	No	Yes	0	6	5
1260	S:S:F194	S:S:K173	7.44	No	No	0	7	4
1261	S:S:L446	S:S:P175	8.21	No	No	0	6	8
1262	S:S:F195	S:S:Q176	8.2	Yes	Yes	2	8	8
1263	S:S:I177	S:S:M416	7.29	No	Yes	0	7	6
1264	S:S:I177	S:S:I450	7.36	No	Yes	0	7	7
1265	S:S:S178	S:S:S181	4.89	No	No	0	9	8
1266	S:S:F195	S:S:S178	5.28	Yes	No	0	8	9
1267	S:S:V409	S:S:Y179	8.83	No	Yes	3	7	8
1268	S:S:A180	S:S:K405	6.42	No	Yes	3	6	4
1269	S:S:D202	S:S:T182	10.12	Yes	No	3	8	8
1270	S:S:Q205	S:S:T182	5.67	Yes	No	3	9	8
1271	S:S:D312	S:S:T182	7.23	Yes	No	3	8	8
1272	S:S:A183	S:S:D185	4.63	No	Yes	0	7	4
1273	S:S:P184	S:S:S201	5.34	No	No	0	5	8
1274	S:S:D202	S:S:P184	4.83	Yes	No	0	8	5
1275	S:S:P184	S:S:S233	7.13	No	No	0	5	4
1276	S:S:D185	S:S:L186	5.43	Yes	Yes	2	4	8
1277	S:S:D185	S:S:S229	7.36	Yes	No	0	4	6
1278	S:S:L186	S:S:Y192	3.52	Yes	Yes	2	8	5
1279	S:S:F195	S:S:L186	13.4	Yes	Yes	2	8	8
1280	S:S:R197	S:S:S187	6.59	Yes	No	2	9	8
1281	S:S:D470	S:S:S187	8.83	Yes	No	2	7	8
1282	S:S:D188	S:S:S190	4.42	No	No	0	6	2
1283	S:S:D188	S:S:R191	4.76	No	Yes	0	6	5
1284	S:S:D193	S:S:N189	5.39	No	No	0	6	7
1285	S:S:N189	S:S:R451	7.23	No	Yes	0	7	6
1286	S:S:E467	S:S:N189	7.89	No	No	0	4	7
1287	S:S:R191	S:S:Y192	20.58	Yes	Yes	2	5	5
1288	S:S:F194	S:S:L447	9.74	No	No	0	7	6
1289	S:S:F195	S:S:R197	12.83	Yes	Yes	2	8	9
1290	S:S:I450	S:S:S196	4.64	Yes	No	54	7	6
1291	S:S:R451	S:S:S196	6.59	Yes	No	0	6	6
1292	S:S:F465	S:S:S196	6.61	No	No	54	8	6
1293	S:S:R197	S:S:V199	3.92	Yes	No	0	9	7
1294	S:S:R197	S:S:S201	3.95	Yes	No	0	9	8
1295	S:S:D470	S:S:R197	10.72	Yes	Yes	2	7	9
1296	S:S:D411	S:S:V198	5.84	No	No	0	8	9
1297	S:S:P200	S:S:V199	3.53	Yes	No	0	7	7
1298	S:S:F408	S:S:V199	7.87	Yes	No	0	7	7
1299	S:S:A471	S:S:P200	3.74	No	Yes	0	4	7
1300	S:S:G473	S:S:P200	4.06	No	Yes	0	5	7
1301	S:S:P200	S:S:Y475	9.74	Yes	Yes	0	7	8
1302	S:S:S201	S:S:T203	7.99	No	No	0	8	3
1303	S:S:D202	S:S:Q205	13.05	Yes	Yes	3	8	9
1304	S:S:D202	S:S:Y230	6.9	Yes	Yes	3	8	7
1305	S:S:T203	S:S:Y204	6.24	No	Yes	0	3	4
1306	S:S:G473	S:S:Y204	4.35	No	Yes	0	5	4
1307	S:S:Y204	S:S:Y475	3.97	Yes	Yes	0	4	8
1308	S:S:W495	S:S:Y204	3.86	Yes	Yes	0	5	4
1309	S:S:D312	S:S:Q205	11.75	Yes	Yes	3	8	9
1310	S:S:Q205	S:S:Y475	12.4	Yes	Yes	0	9	8
1311	S:S:Q207	S:S:V210	4.3	Yes	Yes	0	4	6
1312	S:S:D211	S:S:Q207	7.83	Yes	Yes	19	5	4
1313	S:S:K241	S:S:Q207	12.2	No	Yes	0	5	4
1314	S:S:Q207	S:S:W495	4.38	Yes	Yes	19	4	5
1315	S:S:A208	S:S:W495	10.37	No	Yes	0	7	5
1316	S:S:F238	S:S:M209	3.73	No	No	0	7	7
1317	S:S:F284	S:S:M209	6.22	Yes	No	0	8	7
1318	S:S:R214	S:S:V210	7.85	Yes	Yes	0	4	6
1319	S:S:F238	S:S:V210	3.93	No	Yes	0	7	6
1320	S:S:D211	S:S:R214	3.57	Yes	Yes	0	5	4
1321	S:S:D211	S:S:W495	6.7	Yes	Yes	19	5	5
1322	S:S:D211	S:S:L499	4.07	Yes	Yes	19	5	7
1323	S:S:I212	S:S:I477	8.83	No	No	0	8	7
1324	S:S:I212	S:S:L499	7.14	No	Yes	19	8	7
1325	S:S:I212	S:S:L501	5.71	No	Yes	19	8	7
1326	S:S:V213	S:S:W218	7.36	No	Yes	0	6	9
1327	S:S:D245	S:S:R214	14.29	No	Yes	0	4	4
1328	S:S:G246	S:S:R214	7.51	No	Yes	0	7	4
1329	S:S:L216	S:S:W218	15.94	No	Yes	0	8	9
1330	S:S:L216	S:S:M506	4.24	No	No	0	8	7
1331	S:S:A280	S:S:W218	5.19	No	Yes	0	8	9
1332	S:S:F307	S:S:W218	9.02	No	Yes	0	7	9
1333	S:S:S518	S:S:W218	12.36	No	Yes	0	9	9
1334	S:S:I519	S:S:N219	8.5	No	No	0	5	6
1335	S:S:A251	S:S:Y220	8.01	No	Yes	0	8	9
1336	S:S:C520	S:S:Y220	14.79	No	Yes	55	9	9
1337	S:S:C539	S:S:Y220	4.03	No	Yes	55	9	9
1338	S:S:I282	S:S:V221	4.61	No	No	0	7	7
1339	S:S:L272	S:S:S222	4.5	Yes	No	23	8	8
1340	S:S:S222	S:S:V281	8.08	No	Yes	23	8	6
1341	S:S:I250	S:S:T223	7.6	No	No	0	6	5
1342	S:S:V224	S:S:V254	4.81	No	No	0	5	5
1343	S:S:L272	S:S:V224	4.47	Yes	No	0	8	5
1344	S:S:I283	S:S:V224	4.61	No	No	0	5	5
1345	S:S:A225	S:S:V235	5.09	No	No	0	5	5
1346	S:S:I256	S:S:S226	4.64	Yes	No	0	5	7
1347	S:S:E227	S:S:K255	10.8	No	No	0	7	4
1348	S:S:E227	S:S:R258	5.82	No	No	0	7	4
1349	S:S:G228	S:S:R258	4.5	No	No	0	6	4
1350	S:S:G231	S:S:Y230	4.35	No	Yes	0	8	7
1351	S:S:S311	S:S:Y230	3.82	No	Yes	0	8	7
1352	S:S:S313	S:S:Y230	3.82	No	Yes	3	6	7
1353	S:S:E232	S:S:K255	12.15	No	No	0	5	4
1354	S:S:G234	S:S:S233	3.71	No	No	0	7	4
1355	S:S:F284	S:S:G234	6.02	Yes	No	0	8	7
1356	S:S:F284	S:S:V235	5.24	Yes	No	0	8	5
1357	S:S:E236	S:S:Q240	12.74	No	No	0	5	4
1358	S:S:F238	S:S:I282	5.02	No	No	0	7	7
1359	S:S:C249	S:S:M536	4.86	No	No	0	9	6
1360	S:S:C249	S:S:C538	5.46	No	No	0	9	9
1361	S:S:E274	S:S:Q252	11.47	No	No	0	4	6
1362	S:S:I268	S:S:V254	6.14	No	No	0	5	5
1363	S:S:R271	S:S:V254	6.54	No	No	0	3	5
1364	S:S:F265	S:S:I256	3.77	Yes	Yes	24	4	5
1365	S:S:I256	S:S:I268	5.89	Yes	No	0	5	5
1366	S:S:D289	S:S:I256	7	Yes	Yes	24	4	5
1367	S:S:E264	S:S:P257	11	No	No	0	3	4
1368	S:S:F265	S:S:P260	7.22	Yes	No	24	4	2
1369	S:S:P260	S:S:R292	12.97	No	No	24	2	1
1370	S:S:G263	S:S:K261	5.23	No	No	0	1	3
1371	S:S:D266	S:S:G263	5.03	No	No	0	3	1
1372	S:S:D289	S:S:F265	4.78	Yes	Yes	24	4	4
1373	S:S:F265	S:S:R292	22.45	Yes	No	24	4	1
1374	S:S:F265	S:S:V293	5.24	Yes	No	0	4	5
1375	S:S:D266	S:S:R270	4.76	No	No	0	3	1
1376	S:S:K267	S:S:R270	4.95	No	No	0	2	1
1377	S:S:F306	S:S:I269	3.77	Yes	Yes	0	7	4
1378	S:S:L272	S:S:V281	4.47	Yes	Yes	23	8	6
1379	S:S:F306	S:S:L272	3.65	Yes	Yes	23	7	8
1380	S:S:L273	S:S:Q302	11.98	No	No	0	5	4
1381	S:S:F306	S:S:L273	4.87	Yes	No	0	7	5
1382	S:S:H305	S:S:R279	6.77	Yes	No	0	3	6
1383	S:S:F307	S:S:R279	9.62	No	No	0	7	6
1384	S:S:F306	S:S:V281	3.93	Yes	Yes	23	7	6
1385	S:S:V281	S:S:W308	4.9	Yes	Yes	23	6	7
1386	S:S:I282	S:S:M309	4.37	No	No	0	7	6
1387	S:S:I283	S:S:W308	4.7	No	Yes	0	5	7
1388	S:S:I283	S:S:W314	5.87	No	Yes	0	5	7
1389	S:S:F284	S:S:S311	7.93	Yes	No	0	8	8
1390	S:S:A285	S:S:D289	4.63	No	Yes	0	4	4
1391	S:S:D289	S:S:N286	5.39	Yes	No	0	4	5
1392	S:S:E287	S:S:S313	4.31	Yes	No	0	3	6
1393	S:S:E287	S:S:K317	5.4	Yes	No	0	3	6
1394	S:S:E287	S:S:P320	9.43	Yes	No	0	3	5
1395	S:S:D288	S:S:R292	11.91	No	No	0	1	1
1396	S:S:I290	S:S:W314	16.44	No	Yes	0	4	7
1397	S:S:L322	S:S:R291	4.86	No	No	0	3	1
1398	S:S:H323	S:S:R291	14.67	Yes	No	0	1	1
1399	S:S:H323	S:S:L294	9	Yes	Yes	0	1	5
1400	S:S:L294	S:S:V327	4.47	Yes	No	0	5	3
1401	S:S:E295	S:S:R299	17.45	No	No	0	2	3
1402	S:S:E295	S:S:H323	4.92	No	Yes	0	2	1
1403	S:S:A296	S:S:R299	4.15	No	No	0	5	3
1404	S:S:H323	S:S:R298	12.41	Yes	No	0	1	3
1405	S:S:E326	S:S:R298	10.47	No	No	0	3	3
1406	S:S:R298	S:S:V327	9.15	No	No	0	3	3
1407	S:S:H305	S:S:Q302	12.36	Yes	No	0	3	4
1408	S:S:E329	S:S:T303	5.64	Yes	No	0	5	6
1409	S:S:E329	S:S:G304	4.91	Yes	No	0	5	3
1410	S:S:F306	S:S:H305	11.31	Yes	Yes	0	7	3
1411	S:S:F306	S:S:W308	9.02	Yes	Yes	23	7	7
1412	S:S:F307	S:S:P516	5.78	No	No	0	7	8
1413	S:S:M309	S:S:V332	6.09	No	No	0	6	5
1414	S:S:G310	S:S:W314	7.04	No	Yes	0	7	7
1415	S:S:D312	S:S:P336	9.66	Yes	Yes	0	8	5
1416	S:S:D312	S:S:K405	11.06	Yes	Yes	3	8	4
1417	S:S:P320	S:S:W314	8.11	No	Yes	0	5	7
1418	S:S:G315	S:S:L335	6.84	No	No	0	5	5
1419	S:S:S316	S:S:Y489	11.45	No	Yes	0	5	5
1420	S:S:E403	S:S:K317	5.4	Yes	No	0	5	6
1421	S:S:V321	S:S:Y480	17.66	No	No	57	4	6
1422	S:S:V321	S:S:Y489	5.05	No	Yes	57	4	5
1423	S:S:E325	S:S:E329	21.57	No	Yes	56	4	5
1424	S:S:E325	S:S:L482	13.25	No	No	0	4	3
1425	S:S:E325	S:S:W508	5.45	No	No	56	4	8
1426	S:S:E329	S:S:W508	9.81	Yes	No	56	5	8
1427	S:S:G330	S:S:Q479	4.93	No	Yes	0	8	8
1428	S:S:T333	S:S:Y489	6.24	No	Yes	0	7	5
1429	S:S:I334	S:S:Y475	7.25	No	Yes	0	7	8
1430	S:S:L335	S:S:P336	4.93	No	Yes	0	5	5
1431	S:S:F408	S:S:P336	5.78	Yes	Yes	0	7	5
1432	S:S:P336	S:S:Y475	9.74	Yes	Yes	0	5	8
1433	S:S:K337	S:S:R474	18.56	No	No	0	5	4
1434	S:S:D476	S:S:K337	15.21	No	No	0	8	5
1435	S:S:K337	S:S:S494	4.59	No	No	0	5	3
1436	S:S:G404	S:S:R338	9.01	No	No	0	5	5
1437	S:S:A459	S:S:M339	4.83	No	No	0	4	3
1438	S:S:Q402	S:S:S340	8.66	Yes	No	0	6	3
1439	S:S:F344	S:S:V341	3.93	Yes	No	0	8	6
1440	S:S:I458	S:S:V341	4.61	No	No	0	3	6
1441	S:S:G343	S:S:R346	7.51	No	No	0	5	3
1442	S:S:F344	S:S:F348	6.43	Yes	No	0	8	7
1443	S:S:F344	S:S:Q402	7.03	Yes	Yes	0	8	6
1444	S:S:D345	S:S:Y400	5.75	No	No	0	4	5
1445	S:S:D345	S:S:Q402	5.22	No	Yes	0	4	6
1446	S:S:R351	S:S:Y347	21.61	Yes	No	0	5	7
1447	S:S:R358	S:S:Y347	5.14	Yes	No	0	4	7
1448	S:S:F348	S:S:Y400	7.22	No	No	0	7	5
1449	S:S:R351	S:S:S350	3.95	Yes	No	0	5	4
1450	S:S:N355	S:S:R351	8.44	No	Yes	0	4	5
1451	S:S:N356	S:S:R351	6.03	No	Yes	0	4	5
1452	S:S:N355	S:S:T352	4.39	No	No	0	4	4
1453	S:S:L353	S:S:W366	6.83	No	Yes	0	6	6
1454	S:S:N359	S:S:W361	4.52	Yes	Yes	4	7	5
1455	S:S:F362	S:S:N359	7.25	Yes	Yes	4	5	7
1456	S:S:I360	S:S:W361	8.22	No	Yes	0	3	5
1457	S:S:E364	S:S:W361	9.81	Yes	Yes	4	5	5
1458	S:S:F362	S:S:F365	7.5	Yes	No	0	5	6
1459	S:S:F362	S:S:W366	5.01	Yes	Yes	4	5	6
1460	S:S:F370	S:S:W366	10.02	Yes	Yes	4	8	6
1461	S:S:E392	S:S:W366	14.17	Yes	Yes	4	7	6
1462	S:S:I394	S:S:W366	7.05	Yes	Yes	4	5	6
1463	S:S:F370	S:S:N369	21.75	Yes	No	4	8	3
1464	S:S:N369	S:S:S398	8.94	No	No	4	3	3
1465	S:S:E392	S:S:F370	19.82	Yes	Yes	4	7	8
1466	S:S:F370	S:S:I394	3.77	Yes	Yes	4	8	5
1467	S:S:D397	S:S:F370	7.17	No	Yes	0	3	8
1468	S:S:F370	S:S:S398	3.96	Yes	No	4	8	3
1469	S:S:C372	S:S:C388	7.28	No	No	0	8	8
1470	S:S:C388	S:S:E392	6.08	No	Yes	0	8	7
1471	S:S:R391	S:S:T389	3.88	No	No	0	3	6
1472	S:S:I394	S:S:R393	8.77	Yes	No	0	5	4
1473	S:S:Q402	S:S:V406	5.73	Yes	No	0	6	6
1474	S:S:E403	S:S:G404	4.91	Yes	No	0	5	5
1475	S:S:E403	S:S:K405	8.1	Yes	Yes	3	5	4
1476	S:S:F408	S:S:K405	4.96	Yes	Yes	0	7	4
1477	S:S:F408	S:S:Q407	8.2	Yes	No	0	7	7
1478	S:S:I458	S:S:Q407	4.12	No	No	0	3	7
1479	S:S:N461	S:S:Q407	3.96	Yes	No	0	5	7
1480	S:S:D411	S:S:V463	11.69	No	No	0	8	6
1481	S:S:F455	S:S:Y414	5.16	Yes	No	0	9	8
1482	S:S:F455	S:S:H418	23.76	Yes	No	0	9	6
1483	S:S:H421	S:S:R425	6.77	No	No	0	7	3
1484	S:S:L446	S:S:M423	4.24	No	No	0	6	6
1485	S:S:M423	S:S:Y449	8.38	No	Yes	0	6	4
1486	S:S:C428	S:S:H424	5.9	No	No	0	7	5
1487	S:S:D426	S:S:Y449	9.2	No	Yes	0	4	4
1488	S:S:L427	S:S:M438	4.24	No	No	0	3	4
1489	S:S:L427	S:S:Q445	6.65	No	No	0	3	6
1490	S:S:C428	S:S:C435	7.28	No	No	0	7	6
1491	S:S:C428	S:S:M438	4.86	No	No	0	7	4
1492	S:S:C435	S:S:P429	3.77	No	No	0	6	2
1493	S:S:L434	S:S:M438	7.07	No	No	0	3	4
1494	S:S:D439	S:S:P440	8.05	No	No	0	1	3
1495	S:S:D442	S:S:T444	4.34	No	No	0	4	3
1496	S:S:D442	S:S:Q445	3.92	No	No	0	4	6
1497	S:S:K448	S:S:T444	7.51	No	No	0	3	3
1498	S:S:Q445	S:S:Y449	4.51	No	Yes	0	6	4
1499	S:S:I450	S:S:L446	5.71	Yes	No	0	7	6
1500	S:S:L447	S:S:R451	3.64	No	Yes	0	6	6
1501	S:S:F465	S:S:I450	3.77	No	Yes	54	8	7
1502	S:S:G469	S:S:R451	6	No	Yes	0	7	6
1503	S:S:F455	S:S:V463	10.49	Yes	No	0	9	6
1504	S:S:N461	S:S:R474	4.82	Yes	No	0	5	4
1505	S:S:N466	S:S:N468	5.45	No	No	2	7	7
1506	S:S:D470	S:S:N466	5.39	Yes	No	2	7	7
1507	S:S:E467	S:S:N468	11.83	No	No	0	4	7
1508	S:S:D470	S:S:N468	4.04	Yes	No	2	7	7
1509	S:S:R474	S:S:T496	5.17	No	No	0	4	5
1510	S:S:D476	S:S:Y478	9.2	No	No	0	8	4
1511	S:S:V491	S:S:Y478	6.31	No	No	0	5	4
1512	S:S:Q479	S:S:Q481	6.4	Yes	No	0	8	7
1513	S:S:H507	S:S:Q479	7.42	No	Yes	0	4	8
1514	S:S:Y480	S:S:Y489	7.94	No	Yes	57	6	5
1515	S:S:Q481	S:S:W508	9.86	No	No	0	7	8
1516	S:S:D485	S:S:N484	10.77	No	No	0	4	3
1517	S:S:G493	S:S:I492	3.53	No	No	0	9	7
1518	S:S:L499	S:S:W495	6.83	Yes	Yes	19	7	5
1519	S:S:D497	S:S:T496	5.78	No	No	0	2	5
1520	S:S:D497	S:S:H498	13.87	No	No	0	2	4
1521	S:S:H498	S:S:H500	13.14	No	No	0	4	1
1522	S:S:L499	S:S:L501	4.15	Yes	Yes	19	7	7
1523	S:S:L501	S:S:M506	7.07	Yes	No	0	7	7
1524	S:S:R502	S:S:R505	8.53	No	No	0	5	3
1525	S:S:E504	S:S:R505	4.65	No	No	0	3	3
1526	S:S:H507	S:S:P516	15.25	No	No	0	4	8
1527	S:S:L515	S:S:P516	4.93	No	No	0	4	8
1528	S:S:I519	S:S:R517	8.77	No	No	0	5	1
1529	S:S:C520	S:S:C539	7.28	No	No	55	9	9
1530	S:S:C524	S:S:C542	7.28	No	No	58	9	9
1531	S:S:P526	S:S:Q525	6.32	No	Yes	0	6	1
1532	S:S:E528	S:S:Q525	12.74	No	Yes	0	5	1
1533	S:S:Q525	S:S:R529	10.51	Yes	No	0	1	6
1534	S:S:G527	S:S:Q551	6.58	No	No	0	9	8
1535	S:S:E528	S:S:N569	3.94	No	No	0	5	4
1536	S:S:P544	S:S:R529	8.65	No	No	0	4	6
1537	S:S:K530	S:S:T532	4.5	No	No	0	8	3
1538	S:S:E543	S:S:K530	5.4	No	No	0	4	8
1539	S:S:C545	S:S:K530	4.85	No	No	0	9	8
1540	S:S:H541	S:S:T532	4.11	No	No	0	6	3
1541	S:S:E543	S:S:P544	7.86	No	No	0	4	4
1542	S:S:C545	S:S:Q549	4.58	No	Yes	59	9	7
1543	S:S:C545	S:S:C557	7.28	No	No	59	9	9
1544	S:S:G547	S:S:T546	5.46	No	No	0	5	5
1545	S:S:Q549	S:S:T546	4.25	Yes	No	0	7	5
1546	S:S:G547	S:S:R570	6	No	No	0	5	6
1547	S:S:T559	S:S:Y548	6.24	No	No	0	3	8
1548	S:S:Q732	S:S:Y548	5.64	No	No	0	6	8
1549	S:S:R738	S:S:Y548	7.2	No	No	0	4	8
1550	S:S:C557	S:S:Q549	6.1	No	Yes	59	9	7
1551	S:S:Q549	S:S:T559	4.25	Yes	No	0	7	3
1552	S:S:V552	S:S:Y550	8.83	No	Yes	0	6	7
1553	S:S:C560	S:S:Y550	6.72	Yes	Yes	60	9	7
1554	S:S:C573	S:S:Y550	10.75	No	Yes	60	9	7
1555	S:S:K558	S:S:V552	7.59	No	No	0	1	6
1556	S:S:D553	S:S:R554	11.91	No	No	0	7	7
1557	S:S:T556	S:S:Y555	8.74	No	No	0	4	3
1558	S:S:K558	S:S:T556	6.01	No	No	0	1	4
1559	S:S:C560	S:S:M564	4.86	Yes	No	0	9	5
1560	S:S:C560	S:S:C573	7.28	Yes	No	60	9	9
1561	S:S:D563	S:S:I576	11.2	No	Yes	29	6	8
1562	S:S:D563	S:S:D728	5.32	No	No	29	6	6
1563	S:S:D563	S:S:D731	7.98	No	Yes	29	6	6
1564	S:S:I576	S:S:R565	7.52	Yes	No	0	8	7
1565	S:S:P566	S:S:R738	7.21	No	No	0	8	4
1566	S:S:N569	S:S:T571	8.77	No	No	0	4	6
1567	S:S:P575	S:S:R574	7.21	No	No	0	3	4
1568	S:S:D731	S:S:I576	11.2	Yes	Yes	29	6	8
1569	S:S:I578	S:S:L744	4.28	No	No	0	5	7
1570	S:S:I579	S:S:R741	11.27	No	No	0	5	5
1571	S:S:I579	S:S:Y816	8.46	No	No	0	5	5
1572	S:S:L581	S:S:S585	4.5	No	No	0	8	7
1573	S:S:E582	S:S:W583	27.26	No	No	0	6	5
1574	S:S:A645	S:S:E582	4.53	No	No	0	7	6
1575	S:S:E582	S:S:E646	3.81	No	No	0	6	5
1576	S:S:P586	S:S:S585	3.56	No	No	0	4	7
1577	S:S:I817	S:S:W587	8.22	No	No	0	5	5
1578	S:S:L590	S:S:P591	4.93	No	No	0	4	8
1579	S:S:L590	X:X:?1	8.25	No	Yes	0	4	0
1580	S:S:P591	S:S:V824	5.3	No	No	0	8	7
1581	S:S:F593	S:S:L594	6.09	No	No	0	2	4
1582	S:S:F593	S:S:V597	6.55	No	No	0	2	2
1583	S:S:A595	S:S:F641	8.32	No	Yes	0	7	7
1584	S:S:F641	S:S:V596	3.93	Yes	No	0	7	3
1585	S:S:G598	S:S:Y637	8.69	No	Yes	0	7	8
1586	S:S:I599	S:S:Y637	3.63	Yes	Yes	0	6	8
1587	S:S:F641	S:S:I599	3.77	Yes	Yes	0	7	6
1588	S:S:F604	S:S:T608	6.49	No	No	0	4	6
1589	S:S:L630	S:S:V605	5.96	No	No	13	9	6
1590	S:S:V605	S:S:Y838	7.57	No	Yes	13	6	9
1591	S:S:I607	S:S:R611	3.76	No	No	0	1	4
1592	S:S:F609	S:S:Y838	7.22	No	Yes	13	8	9
1593	S:S:F609	S:S:K841	4.96	No	Yes	13	8	9
1594	S:S:V610	S:S:Y627	3.79	No	No	0	4	7
1595	S:S:R611	S:S:Y612	12.35	No	No	0	4	5
1596	S:S:I845	S:S:Y612	3.63	No	No	0	8	5
1597	S:S:D614	S:S:N613	5.39	No	No	0	5	6
1598	S:S:K619	S:S:N613	9.79	No	No	0	7	6
1599	S:S:P616	S:S:T615	5.25	No	No	0	8	9
1600	S:S:I617	S:S:T615	4.56	No	No	0	7	9
1601	S:S:K841	S:S:V618	9.11	Yes	No	0	9	9
1602	S:S:K619	S:S:R623	18.56	No	Yes	0	7	8
1603	S:S:A620	S:S:R623	4.15	No	Yes	0	9	8
1604	S:S:G622	S:S:S621	3.71	No	No	0	9	9
1605	S:S:N782	S:S:S621	5.96	No	No	13	9	9
1606	S:S:E783	S:S:S621	5.75	Yes	No	13	9	9
1607	S:S:G622	S:S:S626	3.71	No	No	0	9	8
1608	S:S:L625	S:S:T672	4.42	No	Yes	20	8	7
1609	S:S:K673	S:S:L625	7.05	No	No	0	9	8
1610	S:S:L625	S:S:Q699	6.65	No	Yes	20	8	8
1611	S:S:S626	S:S:Y838	7.63	No	Yes	0	8	9
1612	S:S:L629	S:S:Y838	5.86	No	Yes	0	8	9
1613	S:S:L630	S:S:Y838	11.72	No	Yes	13	9	9
1614	S:S:G632	S:S:I665	3.53	No	No	0	8	7
1615	S:S:I633	S:S:Y637	3.63	Yes	Yes	62	9	8
1616	S:S:A830	S:S:I633	4.87	No	Yes	62	8	9
1617	S:S:S827	S:S:Y637	5.09	No	Yes	0	9	8
1618	S:S:A830	S:S:Y637	4	No	Yes	62	8	8
1619	S:S:S831	S:S:Y637	5.09	No	Yes	0	5	8
1620	S:S:T640	S:S:T823	4.71	No	No	0	7	7
1621	S:S:S827	S:S:T640	7.99	No	No	0	9	7
1622	S:S:M643	S:S:R655	6.2	No	No	0	7	8
1623	S:S:M643	S:S:T823	4.52	No	No	0	7	7
1624	S:S:L744	S:S:P647	4.93	No	No	0	7	9
1625	S:S:D648	S:S:T651	7.23	No	No	0	5	6
1626	S:S:H724	S:S:L649	3.86	No	No	0	4	3
1627	S:S:C652	S:S:R655	5.57	No	No	0	9	8
1628	S:S:C652	S:S:C746	7.28	No	No	0	9	9
1629	S:S:K745	S:S:R655	6.19	Yes	No	0	7	8
1630	S:S:R656	S:S:W717	17.99	No	Yes	0	8	8
1631	S:S:F718	S:S:R656	4.28	Yes	No	0	7	8
1632	S:S:F658	S:S:I657	5.02	No	No	0	6	5
1633	S:S:L659	S:S:M663	4.24	No	No	0	8	8
1634	S:S:M663	S:S:V826	6.09	No	Yes	0	8	8
1635	S:S:I665	S:S:S664	4.64	No	No	0	7	7
1636	S:S:Q710	S:S:S664	12.99	No	No	0	9	7
1637	S:S:I665	S:S:I707	5.89	No	No	0	7	7
1638	S:S:T794	S:S:Y667	7.49	No	No	0	8	6
1639	S:S:I787	S:S:L670	11.42	No	No	0	9	7
1640	S:S:L671	S:S:T766	5.9	No	No	0	8	4
1641	S:S:Q699	S:S:T672	8.5	Yes	Yes	20	8	7
1642	S:S:I702	S:S:T672	4.56	No	Yes	0	6	7
1643	S:S:T672	S:S:T703	6.28	Yes	Yes	0	7	7
1644	S:S:I787	S:S:K673	4.36	No	No	0	9	9
1645	S:S:I677	S:S:T674	4.56	No	No	0	9	9
1646	S:S:T674	S:S:Y770	6.24	No	No	0	9	7
1647	S:S:N675	S:S:R679	9.64	No	No	0	6	7
1648	S:S:N675	S:S:Y770	15.12	No	No	0	6	7
1649	S:S:I680	S:S:R676	7.52	No	No	20	9	8
1650	S:S:I694	S:S:R676	13.78	No	No	20	7	8
1651	S:S:Q699	S:S:R676	11.68	Yes	No	20	8	8
1652	S:S:I677	S:S:T774	6.08	No	No	0	9	8
1653	S:S:E682	S:S:Y678	4.49	No	No	0	6	6
1654	S:S:K773	S:S:Y678	8.36	No	No	0	7	6
1655	S:S:I680	S:S:I694	8.83	No	No	20	9	7
1656	S:S:F781	S:S:I680	3.77	No	No	0	9	9
1657	S:S:F681	S:S:V777	7.87	No	Yes	0	9	8
1658	S:S:Q683	S:S:R692	7.01	No	No	0	5	5
1659	S:S:F693	S:S:S698	11.89	No	No	0	5	7
1660	S:S:P696	S:S:S695	3.56	No	No	0	6	7
1661	S:S:F704	S:S:L700	14.61	No	No	0	4	5
1662	S:S:Q710	S:S:Y759	6.76	No	Yes	0	9	8
1663	S:S:F718	S:S:I714	3.77	Yes	No	0	7	6
1664	S:S:D721	S:S:W717	5.58	Yes	Yes	0	6	8
1665	S:S:S752	S:S:W717	4.94	No	Yes	0	6	8
1666	S:S:D721	S:S:V720	5.84	Yes	No	0	6	4
1667	S:S:D721	S:S:D747	5.32	Yes	No	0	6	5
1668	S:S:L744	S:S:S725	4.5	No	No	0	7	5
1669	S:S:D728	S:S:V727	10.22	No	No	0	6	4
1670	S:S:D728	S:S:D731	10.65	No	Yes	29	6	6
1671	S:S:F729	S:S:Q730	8.2	No	No	0	4	3
1672	S:S:D736	S:S:R733	5.96	No	No	0	3	6
1673	S:S:F739	S:S:R733	6.41	No	No	0	3	6
1674	S:S:A740	S:S:R733	8.3	No	No	0	4	6
1675	S:S:L735	S:S:T734	5.9	No	No	0	6	4
1676	S:S:D736	S:S:P737	4.83	No	No	0	3	5
1677	S:S:F739	S:S:P737	7.22	No	No	0	3	5
1678	S:S:L815	S:S:V743	5.96	No	No	0	6	6
1679	S:S:V743	S:S:Y816	5.05	No	No	0	6	5
1680	S:S:I748	S:S:K745	11.63	No	Yes	0	5	7
1681	S:S:K745	S:S:L815	8.46	Yes	No	0	7	6
1682	S:S:I748	S:S:S752	7.74	No	No	0	5	6
1683	S:S:D750	S:S:I754	8.4	No	No	0	3	5
1684	S:S:D750	S:S:F805	5.97	No	No	0	3	8
1685	S:S:L753	S:S:L757	5.54	No	No	0	7	8
1686	S:S:L753	S:S:L822	6.92	No	No	0	7	8
1687	S:S:L757	S:S:M761	4.24	No	Yes	0	8	6
1688	S:S:F801	S:S:L757	7.31	Yes	No	0	9	8
1689	S:S:L763	S:S:Y759	15.24	No	Yes	0	9	8
1690	S:S:M761	S:S:S760	4.6	Yes	No	0	6	8
1691	S:S:M761	S:S:W798	15.12	Yes	Yes	0	6	9
1692	S:S:M764	S:S:T794	7.53	No	No	0	8	8
1693	S:S:M764	S:S:W798	4.65	No	Yes	0	8	9
1694	S:S:C767	S:S:M791	6.48	No	Yes	0	8	9
1695	S:S:M791	S:S:T768	6.02	Yes	No	0	9	8
1696	S:S:K773	S:S:V769	4.55	No	No	0	7	5
1697	S:S:I772	S:S:Y792	3.63	No	No	0	8	9
1698	S:S:P778	S:S:V777	3.53	No	Yes	0	9	8
1699	S:S:F781	S:S:V777	6.55	No	Yes	0	9	8
1700	S:S:E783	S:S:N782	3.94	Yes	No	13	9	9
1701	S:S:E783	S:S:L837	7.95	Yes	No	0	9	8
1702	S:S:E783	S:S:K841	9.45	Yes	Yes	13	9	9
1703	S:S:K785	S:S:P786	5.02	No	No	0	9	5
1704	S:S:F789	S:S:K785	12.41	No	No	0	9	9
1705	S:S:F789	S:S:M836	6.22	No	No	5	9	7
1706	S:S:T793	S:S:V832	11.11	Yes	No	5	8	7
1707	S:S:F801	S:S:W798	10.02	Yes	Yes	5	9	9
1708	S:S:S825	S:S:W798	4.94	No	Yes	5	8	9
1709	S:S:F801	S:S:I802	3.77	Yes	No	0	9	7
1710	S:S:F801	S:S:S825	7.93	Yes	No	5	9	8
1711	S:S:F806	S:S:I802	3.77	No	No	0	6	7
1712	S:S:F806	S:S:P803	7.22	No	No	0	6	9
1713	S:S:I804	S:S:T821	9.12	No	No	5	7	8
1714	S:S:I804	X:X:?1	5.32	No	Yes	5	7	0
1715	S:S:I817	S:S:T808	6.08	No	No	0	5	8
1716	S:S:Q810	S:S:S809	7.22	No	No	0	8	6
1717	S:S:D813	S:S:Y816	6.9	No	No	0	4	5
1718	S:S:K814	S:S:Q818	5.42	No	No	0	6	6
1719	S:S:T821	X:X:?1	4.4	No	Yes	5	8	0
1720	S:S:V824	X:X:?1	18.88	No	Yes	0	7	0
1721	S:S:S825	X:X:?1	6.72	No	Yes	5	8	0
1722	S:S:L828	X:X:?1	4.13	No	Yes	5	6	0
1723	S:S:L834	S:S:Y838	4.69	No	Yes	0	8	9
1724	S:S:K841	S:S:Y838	3.58	Yes	Yes	13	9	9
1725	S:S:F847	S:S:Y843	14.44	No	No	0	5	8
1726	R:R:Q402	R:R:R338	3.5	Yes	No	0	6	5
1727	R:R:P591	R:R:T820	3.5	Yes	No	0	8	8
1728	R:R:P591	R:R:T823	3.5	Yes	No	0	8	7
1729	R:R:P616	R:R:T615	3.5	No	Yes	0	8	9
1730	S:S:P472	S:S:T464	3.5	No	No	0	3	3
1731	A:A:G202	A:A:K46	3.49	No	Yes	0	9	9
1732	B:B:G53	B:B:K89	3.49	No	Yes	0	9	9
1733	B:B:N125	B:B:Y111	3.49	Yes	Yes	0	4	4
1734	R:R:E148	R:R:R149	3.49	No	No	0	4	3
1735	R:R:G535	R:R:K534	3.49	No	No	0	7	6
1736	R:R:G835	R:R:M839	3.49	No	No	0	3	3
1737	S:S:G152	S:S:M416	3.49	No	Yes	0	8	6
1738	S:S:G835	S:S:M839	3.49	No	No	0	3	3
1739	A:A:C351	R:R:S695	3.44	Yes	No	0	4	7
1740	B:B:C166	B:B:S160	3.44	No	No	0	8	6
1741	S:S:C520	S:S:S521	3.44	No	No	0	9	8
1742	A:A:A31	R:R:S689	3.42	No	No	0	4	5
1743	A:A:A41	A:A:S44	3.42	No	No	0	8	9
1744	R:R:A183	R:R:S159	3.42	No	Yes	0	7	9
1745	R:R:A285	R:R:S226	3.42	No	No	0	4	7
1746	R:R:C636	R:R:V826	3.42	No	No	0	6	8
1747	R:R:G660	R:R:L756	3.42	No	No	0	6	7
1748	R:R:G835	R:R:L834	3.42	No	No	0	3	8
1749	S:S:L294	S:S:W314	3.42	Yes	Yes	0	5	7
1750	S:S:C636	S:S:V826	3.42	No	Yes	0	6	8
1751	S:S:G650	S:S:L649	3.42	No	No	0	3	3
1752	B:B:G144	B:B:N119	3.39	No	No	0	8	9
1753	B:B:A231	B:B:V276	3.39	No	No	0	5	6
1754	B:B:A287	B:B:V276	3.39	No	No	0	6	6
1755	R:R:A156	R:R:V161	3.39	No	Yes	0	6	4
1756	R:R:I174	R:R:P175	3.39	No	Yes	0	6	8
1757	R:R:I450	R:R:P175	3.39	No	Yes	0	7	8
1758	R:R:A280	R:R:V221	3.39	No	No	0	8	7
1759	R:R:I576	R:R:P577	3.39	No	No	0	8	3
1760	S:S:A412	S:S:V198	3.39	No	No	0	9	9
1761	S:S:I256	S:S:P257	3.39	Yes	No	0	5	4
1762	S:S:I576	S:S:P577	3.39	Yes	No	0	8	3
1763	S:S:I644	S:S:P591	3.39	No	No	0	8	8
1764	S:S:F847	S:S:H848	3.39	No	No	0	5	7
1765	R:R:E682	R:R:Y678	3.37	No	No	0	6	6
1766	B:B:D205	B:B:G185	3.35	No	No	0	9	5
1767	R:R:D46	R:R:G47	3.35	No	No	0	4	9
1768	R:R:D245	R:R:G246	3.35	No	No	0	4	7
1769	R:R:K580	R:R:P647	3.35	Yes	Yes	0	6	9
1770	S:S:D442	S:S:G443	3.35	No	No	0	4	5
1771	S:S:D731	S:S:G742	3.35	Yes	No	0	6	7
1772	S:S:T820	X:X:?1	3.3	No	Yes	0	8	0
1773	S:S:G395	S:S:Q396	3.29	No	No	0	3	1
1774	S:S:G660	S:S:Q710	3.29	No	No	0	6	9
1775	R:R:L522	R:R:P523	3.28	No	No	0	4	5
1776	R:R:L590	R:R:P591	3.28	No	Yes	0	4	8
1777	S:S:L522	S:S:P523	3.28	No	No	0	4	5
1778	B:B:C250	B:B:I273	3.27	No	No	0	8	6
1779	S:S:E63	S:S:G64	3.27	No	No	0	1	1
1780	R:R:S811	S:S:S811	3.26	No	No	52	8	8
1781	S:S:S695	S:S:S698	3.26	No	No	0	7	7
1782	A:A:I19	B:B:A92	3.25	No	No	0	9	6
1783	A:A:A220	A:A:I265	3.25	No	No	0	8	9
1784	A:A:A299	A:A:I278	3.25	No	No	0	7	6
1785	R:R:A412	R:R:I177	3.25	No	No	0	9	7
1786	R:R:A297	R:R:I269	3.25	No	No	0	4	4
1787	R:R:A419	R:R:I450	3.25	No	No	0	8	7
1788	R:R:A830	R:R:I633	3.25	No	Yes	0	8	9
1789	R:R:A771	R:R:I787	3.25	No	Yes	0	9	9
1790	R:R:A800	S:S:I804	3.25	No	No	0	7	7
1791	S:S:A81	S:S:I410	3.25	No	No	0	7	7
1792	S:S:A297	S:S:I269	3.25	No	Yes	0	4	4
1793	S:S:A419	S:S:I450	3.25	No	Yes	0	8	7
1794	S:S:A588	S:S:I644	3.25	No	No	0	8	8
1795	R:R:C538	R:R:M536	3.24	No	No	0	9	6
1796	R:R:C795	R:R:M764	3.24	No	No	0	6	8
1797	S:S:C795	S:S:M764	3.24	No	No	0	6	8
1798	B:B:S279	B:B:V320	3.23	No	No	0	9	7
1799	R:R:S242	R:R:V248	3.23	No	No	0	7	7
1800	R:R:K534	S:S:C539	3.23	No	No	0	6	9
1801	R:R:S825	R:R:V797	3.23	No	No	0	8	8
1802	A:A:A245	A:A:M240	3.22	No	No	0	9	6
1803	B:B:A328	B:B:M61	3.22	No	No	0	5	6
1804	R:R:A459	R:R:M339	3.22	No	No	0	4	3
1805	S:S:A771	S:S:M791	3.22	No	Yes	0	9	9
1806	B:B:V320	B:B:V327	3.21	No	No	0	7	6
1807	R:R:V151	R:R:V441	3.21	No	No	0	4	3
1808	S:S:F84	S:S:R88	3.21	No	No	0	7	8
1809	S:S:A206	S:S:K241	3.21	No	No	0	6	5
1810	S:S:V213	S:S:V248	3.21	No	No	0	6	7
1811	B:B:S265	B:B:T263	3.2	No	No	0	2	1
1812	B:B:S275	B:B:T274	3.2	No	No	0	8	8
1813	R:R:S833	R:R:T790	3.2	No	No	0	7	9
1814	R:R:S811	R:R:T808	3.2	No	No	52	8	8
1815	R:R:T808	S:S:S811	3.2	No	No	52	8	8
1816	S:S:R342	S:S:R346	3.2	No	No	0	4	3
1817	R:R:T108	R:R:V161	3.17	No	Yes	0	6	4
1818	R:R:T303	R:R:V327	3.17	No	Yes	0	6	3
1819	R:R:T615	R:R:V618	3.17	Yes	No	0	9	9
1820	R:R:C767	R:R:L670	3.17	No	No	0	8	7
1821	R:R:C755	R:R:L751	3.17	No	No	0	4	3
1822	R:R:C795	R:R:L799	3.17	No	No	0	6	6
1823	S:S:T223	S:S:V235	3.17	No	No	0	5	5
1824	S:S:C767	S:S:L670	3.17	No	No	0	8	7
1825	S:S:C767	S:S:L671	3.17	No	No	0	8	8
1826	S:S:C715	S:S:L711	3.17	No	No	0	3	4
1827	R:R:P526	R:R:Q525	3.16	No	No	0	6	1
1828	R:R:A328	R:R:L294	3.15	No	Yes	0	7	5
1829	R:R:A668	R:R:L706	3.15	No	No	0	9	5
1830	S:S:A328	S:S:L294	3.15	No	Yes	0	7	5
1831	S:S:A668	S:S:L706	3.15	No	No	0	9	5
1832	R:R:E646	R:R:P647	3.14	No	Yes	0	5	9
1833	S:S:T567	S:S:T571	3.14	No	No	61	7	6
1834	S:S:E783	S:S:P786	3.14	Yes	No	0	9	5
1835	S:S:T790	S:S:T793	3.14	No	Yes	0	9	8
1836	S:S:A459	S:S:N461	3.13	No	Yes	0	4	5
1837	B:B:C271	B:B:D291	3.11	No	No	0	5	8
1838	R:R:I702	R:R:S698	3.1	No	No	0	6	7
1839	S:S:I633	S:S:S666	3.1	Yes	No	0	9	7
1840	S:S:I633	S:S:S833	3.1	Yes	No	0	9	7
1841	S:S:I707	S:S:S708	3.1	No	No	0	7	4
1842	B:B:A193	B:B:D195	3.09	No	No	0	4	5
1843	R:R:A399	R:R:D397	3.09	No	No	0	2	3
1844	S:S:F609	S:S:Y627	3.09	No	No	0	8	7
1845	A:A:I56	A:A:V332	3.07	No	Yes	0	8	7
1846	B:B:M325	B:B:S67	3.07	Yes	No	0	5	5
1847	R:R:I282	R:R:V221	3.07	No	No	0	7	7
1848	R:R:I665	R:R:V628	3.07	No	No	0	7	6
1849	R:R:M663	R:R:S760	3.07	No	No	0	8	8
1850	S:S:I617	S:S:V618	3.07	No	No	0	7	9
1851	S:S:I845	S:S:V618	3.07	No	No	0	8	9
1852	A:A:K32	R:R:S687	3.06	No	No	0	4	4
1853	A:A:I56	A:A:T329	3.04	No	No	0	8	9
1854	R:R:C388	R:R:E392	3.04	No	No	0	8	7
1855	R:R:K531	R:R:V533	3.04	No	No	0	6	5
1856	R:R:M839	R:R:V605	3.04	No	No	0	3	6
1857	R:R:I707	R:R:T703	3.04	No	Yes	0	7	7
1858	S:S:I633	S:S:T602	3.04	Yes	No	0	9	7
1859	S:S:I817	S:S:T820	3.04	No	No	0	5	8
1860	R:R:A319	R:R:E73	3.02	No	Yes	0	1	2
1861	R:R:A487	R:R:E325	3.02	No	No	0	3	4
1862	B:B:F180	B:B:G216	3.01	Yes	No	0	7	4
1863	B:B:F234	B:B:G238	3.01	Yes	No	0	5	7
1864	R:R:F55	R:R:G53	3.01	Yes	No	0	9	7
1865	R:R:F194	R:R:G443	3.01	Yes	No	0	7	5
1866	R:R:F455	R:R:G457	3.01	Yes	No	0	9	6
1867	R:R:M643	R:R:T823	3.01	No	No	0	7	7
1868	S:S:M643	S:S:T819	3.01	No	No	0	7	8
1869	S:S:M791	S:S:T790	3.01	Yes	No	0	9	9
1870	A:A:L249	A:A:S252	3	No	No	0	8	7
1871	B:B:G174	B:B:R137	3	No	No	0	4	5
1872	B:B:L318	B:B:S277	3	No	No	0	6	5
1873	B:B:L284	B:B:S279	3	Yes	No	0	5	9
1874	R:R:G247	R:R:R214	3	No	No	0	5	4
1875	R:R:K337	R:R:T496	3	No	No	0	5	5
1876	R:R:K530	R:R:T532	3	No	No	0	8	3
1877	R:R:L594	R:R:S827	3	No	No	0	4	9
1878	R:R:L649	R:R:S723	3	No	No	0	3	8
1879	S:S:L594	S:S:S827	3	No	No	0	4	9
1880	S:S:L629	S:S:S666	3	No	No	0	8	7
1881	S:S:L661	S:S:S664	3	No	No	0	6	7
1882	S:S:L751	S:S:S749	3	No	No	0	3	8
1883	A:A:L39	A:A:V201	2.98	Yes	No	0	9	9
1884	R:R:L712	R:R:V716	2.98	No	No	0	1	4
1885	R:R:L815	R:R:V743	2.98	No	Yes	0	6	6
1886	R:R:L828	R:R:V797	2.98	No	No	0	6	8
1887	S:S:Y478	S:S:Y489	2.98	No	Yes	0	4	5
1888	S:S:L630	S:S:V606	2.98	No	No	0	9	5
1889	S:S:L712	S:S:V716	2.98	No	No	0	1	4
1890	S:S:L822	S:S:V826	2.98	No	Yes	0	8	8
1891	A:A:N47	A:A:V50	2.96	No	No	0	9	7
1892	B:B:L318	B:B:T329	2.95	No	No	0	6	8
1893	R:R:L815	R:R:T819	2.95	No	No	0	6	8
1894	S:S:L106	S:S:T121	2.95	No	No	0	5	3
1895	S:S:L659	S:S:T639	2.95	No	No	0	8	7
1896	S:S:L700	S:S:T703	2.95	No	Yes	0	5	7
1897	A:A:I55	A:A:I56	2.94	No	No	0	8	8
1898	R:R:D185	R:R:S233	2.94	No	No	0	4	4
1899	R:R:I804	R:R:I817	2.94	No	No	0	7	5
1900	S:S:D112	S:S:S160	2.94	No	No	0	4	5
1901	S:S:I239	S:S:I250	2.94	No	No	0	4	6
1902	B:B:D212	B:B:V213	2.92	No	No	0	9	4
1903	R:R:I154	R:R:M82	2.92	No	No	0	8	8
1904	R:R:D112	R:R:V161	2.92	Yes	Yes	0	4	4
1905	R:R:N569	R:R:T567	2.92	No	No	0	4	7
1906	R:R:I644	R:R:K580	2.91	Yes	Yes	0	8	6
1907	R:R:I617	R:R:K841	2.91	No	Yes	0	7	9
1908	B:B:G109	B:B:Y105	2.9	No	Yes	0	5	6
1909	L:L:?1	R:R:G158	2.9	Yes	No	0	0	4
1910	R:R:G572	R:R:Y550	2.9	No	Yes	0	1	7
1911	B:B:D322	B:B:T65	2.89	No	No	0	1	1
1912	B:B:D163	B:B:T143	2.89	Yes	No	0	9	5
1913	B:B:D247	B:B:T249	2.89	No	Yes	0	9	6
1914	R:R:D442	R:R:T444	2.89	No	No	0	4	3
1915	S:S:D553	S:S:T556	2.89	No	No	0	7	4
1916	S:S:Q699	S:S:S698	2.89	Yes	No	0	8	7
1917	R:R:P66	R:R:R111	2.88	No	No	0	1	5
1918	R:R:P472	R:R:R474	2.88	No	No	0	3	4
1919	R:R:P523	R:R:R517	2.88	No	No	0	5	1
1920	A:A:E318	A:A:S263	2.87	No	No	0	4	7
1921	R:R:K261	R:R:K267	2.87	No	No	0	3	2
1922	R:R:Q407	R:R:V341	2.87	Yes	No	0	7	6
1923	S:S:K373	S:S:K387	2.87	No	No	0	4	1
1924	A:A:I278	A:A:L283	2.85	No	Yes	0	6	7
1925	R:R:I49	R:R:L51	2.85	Yes	No	0	6	7
1926	R:R:I174	R:R:L126	2.85	No	No	0	6	4
1927	R:R:I269	R:R:L273	2.85	No	No	0	4	5
1928	R:R:I714	R:R:L711	2.85	No	No	0	6	4
1929	S:S:I503	S:S:L501	2.85	No	Yes	0	4	7
1930	S:S:I599	S:S:L603	2.85	Yes	No	0	6	2
1931	B:B:Q175	B:B:T173	2.83	No	No	0	4	5
1932	B:B:L300	B:B:M262	2.83	No	No	0	6	4
1933	R:R:Q118	R:R:T121	2.83	No	No	0	5	3
1934	R:R:L659	R:R:M663	2.83	No	No	0	8	8
1935	S:S:Q124	S:S:T121	2.83	No	No	0	7	3
1936	S:S:Q252	S:S:T275	2.83	No	No	0	6	3
1937	S:S:Q818	S:S:T808	2.83	No	No	0	6	8
1938	S:S:L834	S:S:M839	2.83	No	No	0	8	3
1939	R:R:K580	R:R:L581	2.82	Yes	No	0	6	8
1940	S:S:E392	S:S:T389	2.82	Yes	No	0	7	6
1941	R:R:G807	S:S:W587	2.81	No	No	0	8	5
1942	B:B:D267	B:B:I269	2.8	No	No	0	3	4
1943	R:R:C428	R:R:R431	2.79	Yes	No	0	7	3
1944	S:S:P566	S:S:Y550	2.78	No	Yes	0	8	7
1945	A:A:A300	A:A:F323	2.77	No	No	0	5	5
1946	B:B:A106	B:B:F151	2.77	No	Yes	0	6	9
1947	B:B:A208	B:B:F222	2.77	No	Yes	11	6	8
1948	B:B:A208	B:B:F241	2.77	No	Yes	11	6	6
1949	B:B:L210	B:B:L255	2.77	No	No	0	5	6
1950	B:B:L252	B:B:L261	2.77	No	No	0	7	5
1951	B:B:A299	B:B:R283	2.77	No	No	0	5	9
1952	R:R:A415	R:R:F455	2.77	No	Yes	0	8	9
1953	R:R:A415	R:R:F465	2.77	No	No	0	8	8
1954	R:R:L594	R:R:L828	2.77	No	No	0	4	6
1955	S:S:A415	S:S:F455	2.77	No	Yes	0	8	9
1956	S:S:L635	S:S:L661	2.77	No	No	0	6	6
1957	S:S:A638	S:S:F658	2.77	No	No	0	6	6
1958	R:R:L353	R:R:N390	2.75	No	No	0	6	4
1959	R:R:H500	R:R:T496	2.74	No	No	0	1	5
1960	S:S:I492	S:S:Q479	2.74	No	Yes	0	7	8
1961	B:B:E138	B:B:I120	2.73	No	No	0	6	6
1962	S:S:E401	S:S:I318	2.73	No	No	0	5	4
1963	S:S:D354	S:S:L353	2.71	No	No	0	4	6
1964	A:A:E33	A:A:K29	2.7	No	No	0	6	2
1965	S:S:E73	S:S:K72	2.7	No	No	0	2	4
1966	S:S:P523	S:S:W540	2.7	No	No	0	5	8
1967	A:A:C305	A:A:Y302	2.69	No	Yes	0	3	6
1968	B:B:D254	B:B:N239	2.69	No	No	0	9	2
1969	R:R:D354	R:R:N355	2.69	No	No	0	4	4
1970	S:S:C249	S:S:Y220	2.69	No	Yes	0	9	9
1971	B:B:A287	B:B:Y289	2.67	No	Yes	0	6	7
1972	R:R:A278	R:R:Y220	2.67	No	Yes	0	7	9
1973	R:R:A422	R:R:Y449	2.67	No	Yes	0	4	4
1974	S:S:A278	S:S:Y220	2.67	No	Yes	0	7	9
1975	S:S:A422	S:S:Y449	2.67	No	Yes	0	4	4
1976	R:R:H424	R:R:I99	2.65	Yes	Yes	0	5	5
1977	R:R:E325	R:R:L482	2.65	No	No	0	4	3
1978	B:B:N340	G:G:E47	2.63	No	No	0	9	3
1979	R:R:E467	R:R:N466	2.63	No	No	0	4	7
1980	R:R:F408	R:R:V198	2.62	Yes	No	0	7	9
1981	R:R:F465	R:R:V198	2.62	No	No	0	8	9
1982	R:R:F238	R:R:V210	2.62	No	No	0	7	6
1983	R:R:R214	R:R:V248	2.62	No	No	0	4	7
1984	S:S:F455	S:S:V453	2.62	Yes	No	0	9	7
1985	S:S:F465	S:S:V453	2.62	No	No	0	8	7
1986	S:S:F604	S:S:V842	2.62	No	No	0	4	8
1987	R:R:C542	R:R:W540	2.61	No	No	0	9	8
1988	R:R:D731	R:R:Q732	2.61	No	No	0	6	6
1989	R:R:D245	R:R:E244	2.6	No	No	0	4	4
1990	B:B:R150	B:B:T102	2.59	No	No	0	6	8
1991	S:S:H421	S:S:L95	2.57	No	No	0	7	7
1992	R:R:D368	R:R:H371	2.52	No	No	0	3	3
1993	R:R:F172	R:R:I127	2.51	No	No	0	6	4
1994	R:R:F604	R:R:I607	2.51	No	No	0	4	1
1995	R:R:I748	R:R:R656	2.51	No	No	0	5	8
1996	R:R:F704	R:R:I707	2.51	No	No	0	4	7
1997	S:S:F634	S:S:I599	2.51	No	Yes	0	4	6
1998	S:S:F718	S:S:I657	2.51	Yes	No	0	7	5
1999	S:S:F704	S:S:I707	2.51	No	No	0	4	7
2000	A:A:T190	A:A:Y195	2.5	No	No	0	3	4
2001	A:A:M18	A:A:R15	2.48	No	No	0	4	4
2002	A:A:K17	A:A:R21	2.48	No	No	0	4	4
2003	S:S:E403	S:S:H77	2.46	Yes	No	0	5	6
2004	R:R:V826	R:R:W798	2.45	No	No	0	8	9
2005	R:R:L120	S:S:F172	2.44	No	No	0	5	6
2006	R:R:F634	R:R:L603	2.44	No	No	0	4	2
2007	S:S:F172	S:S:L126	2.44	No	No	0	6	4
2008	S:S:F641	S:S:L592	2.44	Yes	No	0	7	6
2009	S:S:L427	S:S:R437	2.43	No	No	0	3	3
2010	B:B:F292	B:B:N313	2.42	No	No	0	4	7
2011	A:A:D337	A:A:F334	2.39	No	Yes	0	4	4
2012	B:B:D258	B:B:F222	2.39	No	Yes	0	7	8
2013	B:B:D303	B:B:R304	2.38	No	No	0	2	5
2014	R:R:Q551	R:R:R554	2.34	No	No	0	8	7
2015	S:S:Q252	S:S:R271	2.34	No	No	0	6	3
2016	S:S:L324	S:S:Y480	2.34	No	No	0	4	6
2017	S:S:Q481	S:S:R483	2.34	No	No	0	7	3
2018	S:S:L671	S:S:Y770	2.34	No	No	0	8	7
2019	S:S:L762	S:S:Y759	2.34	No	Yes	0	4	8
2020	S:S:F805	S:S:Q818	2.34	No	No	0	8	6
2021	R:R:N277	R:R:Y220	2.33	No	Yes	0	6	9
2022	S:S:N277	S:S:Y220	2.33	No	Yes	0	6	9
2023	S:S:E624	S:S:R623	2.33	No	Yes	0	6	8
2024	S:S:K531	S:S:W540	2.32	No	No	0	6	8
2025	S:S:H500	S:S:R502	2.26	No	No	0	1	5
2026	R:R:D497	R:R:W495	2.23	No	Yes	0	2	5
2027	B:B:H62	B:B:Y105	2.18	No	Yes	0	6	6
2028	R:R:R291	R:R:R292	2.13	No	Yes	0	1	1
2029	B:B:G115	B:B:G116	2.11	No	No	0	9	9
2030	R:R:G61	R:R:G68	2.11	No	No	0	2	4
2031	S:S:G102	S:S:G47	2.11	No	No	0	9	9
2032	S:S:G52	S:S:G53	2.11	No	No	0	8	7
2033	S:S:G59	S:S:G68	2.11	No	No	0	3	4
2034	S:S:G61	S:S:G68	2.11	No	No	0	2	4
2035	S:S:G246	S:S:G247	2.11	No	No	0	7	5
2036	R:R:G584	R:R:P586	2.03	No	No	0	4	4
2037	S:S:G430	S:S:P429	2.03	No	No	0	4	2
2038	R:R:C636	R:R:G662	1.96	No	No	0	6	6
2039	S:S:C636	S:S:G662	1.96	No	No	0	6	6
2040	A:A:A30	A:A:G27	1.95	No	No	0	3	5
2041	A:A:A41	A:A:G42	1.95	No	No	0	8	7
2042	B:B:A140	B:B:G141	1.95	No	No	0	5	5
2043	R:R:A237	R:R:G234	1.95	No	No	0	4	7
2044	R:R:A601	R:R:G598	1.95	No	No	0	5	7
2045	S:S:A262	S:S:G263	1.95	No	No	0	2	1
2046	S:S:A601	S:S:G598	1.95	No	No	0	5	7
2047	S:S:A771	S:S:G788	1.95	No	No	0	9	8
2048	R:R:C428	R:R:P429	1.88	Yes	No	0	7	2
2049	R:R:C435	R:R:P436	1.88	No	No	0	6	3
2050	S:S:C435	S:S:P436	1.88	No	No	0	6	3
2051	S:S:C560	S:S:P561	1.88	Yes	No	0	9	4
2052	B:B:A106	B:B:P107	1.87	No	No	0	6	6
2053	B:B:A193	B:B:P194	1.87	No	No	0	4	4
2054	R:R:A690	R:R:P691	1.87	No	Yes	0	5	7
2055	S:S:A471	S:S:P472	1.87	No	No	0	4	3
2056	B:B:G77	B:B:S98	1.86	No	No	0	8	8
2057	R:R:G64	R:R:S62	1.86	No	No	0	1	1
2058	R:R:G632	R:R:S666	1.86	No	No	0	8	7
2059	R:R:G650	R:R:S653	1.86	No	No	0	3	5
2060	S:S:G650	S:S:S653	1.86	No	No	0	3	5
2061	A:A:G202	A:A:V201	1.84	No	No	0	9	9
2062	R:R:G598	R:R:V597	1.84	No	No	0	7	2
2063	R:R:G742	R:R:V743	1.84	No	Yes	0	7	6
2064	S:S:G53	S:S:V153	1.84	No	No	0	7	6
2065	S:S:G713	S:S:V716	1.84	No	No	0	7	4
2066	B:B:G131	B:B:T128	1.82	No	No	0	4	3
2067	R:R:G304	R:R:T303	1.82	No	No	0	3	6
2068	R:R:G572	R:R:T567	1.82	No	No	0	1	7
2069	S:S:G572	S:S:T567	1.82	No	No	61	1	7
2070	S:S:G572	S:S:T571	1.82	No	No	61	1	6
2071	B:B:A73	B:B:C103	1.81	No	No	0	9	8
2072	B:B:A299	G:G:A33	1.79	No	No	0	5	7
2073	R:R:A206	R:R:A237	1.79	No	No	0	6	4
2074	R:R:A800	S:S:A800	1.79	No	No	0	7	7
2075	S:S:A206	S:S:A237	1.79	No	No	0	6	4
2076	A:A:P282	A:A:S281	1.78	No	No	0	5	7
2077	R:R:P462	R:R:S456	1.78	No	No	0	1	5
2078	R:R:P586	R:R:S585	1.78	No	No	0	4	7
2079	R:R:G417	R:R:I89	1.76	No	No	0	9	9
2080	R:R:G788	R:R:I787	1.76	No	Yes	0	8	9
2081	R:R:I804	S:S:G807	1.76	No	No	0	7	8
2082	S:S:G395	S:S:I394	1.76	No	Yes	0	3	5
2083	B:B:P107	B:B:T65	1.75	No	No	0	6	1
2084	R:R:P737	R:R:T734	1.75	No	No	0	5	4
2085	R:R:G758	R:R:M761	1.75	No	No	0	5	6
2086	S:S:G417	S:S:M416	1.75	No	Yes	0	9	6
2087	S:S:G758	S:S:M761	1.75	No	Yes	0	5	6
2088	S:S:P778	S:S:T780	1.75	No	No	0	9	7
2089	B:B:G182	B:B:K209	1.74	No	Yes	0	6	6
2090	B:B:G324	B:B:K280	1.74	No	No	0	9	1
2091	R:R:G75	R:R:K74	1.74	No	Yes	0	5	5
2092	R:R:G263	R:R:K267	1.74	No	No	0	1	2
2093	R:R:G622	R:R:K673	1.74	No	No	0	9	9
2094	S:S:G535	S:S:K534	1.74	No	No	0	7	6
2095	S:S:C746	S:S:S725	1.72	No	No	0	9	5
2096	B:B:A56	B:B:S74	1.71	No	No	0	7	9
2097	B:B:G174	B:B:L139	1.71	No	Yes	0	4	9
2098	B:B:V327	G:G:C41	1.71	No	No	0	6	7
2099	R:R:G584	R:R:L581	1.71	No	No	0	4	8
2100	R:R:G660	R:R:L659	1.71	No	No	0	6	8
2101	R:R:G662	R:R:L661	1.71	No	No	0	6	6
2102	S:S:A278	S:S:S222	1.71	No	No	0	7	8
2103	S:S:A588	S:S:S585	1.71	No	No	0	8	7
2104	S:S:G660	S:S:L756	1.71	No	No	0	6	7
2105	S:S:A697	S:S:S695	1.71	No	No	0	3	7
2106	B:B:A305	B:B:V296	1.7	No	No	0	4	5
2107	B:B:A309	B:B:V307	1.7	No	No	0	3	3
2108	R:R:A669	R:R:V628	1.7	No	No	0	7	6
2109	S:S:A156	S:S:V161	1.7	No	Yes	0	6	4
2110	S:S:G457	S:S:N461	1.7	No	Yes	0	6	5
2111	S:S:G460	S:S:N461	1.7	No	Yes	0	5	5
2112	S:S:A669	S:S:V628	1.7	No	No	0	7	6
2113	S:S:A784	S:S:V777	1.7	No	Yes	0	9	8
2114	R:R:I579	R:R:P647	1.69	No	Yes	0	5	9
2115	B:B:A206	B:B:T223	1.68	No	No	0	4	2
2116	R:R:M536	R:R:P537	1.68	No	No	0	6	4
2117	R:R:D648	R:R:G650	1.68	No	No	0	5	3
2118	R:R:A668	R:R:T703	1.68	No	Yes	0	9	7
2119	R:R:M839	R:R:P840	1.68	No	No	0	3	9
2120	S:S:M536	S:S:P537	1.68	No	No	0	6	4
2121	S:S:A645	S:S:T651	1.68	No	No	0	7	6
2122	S:S:D648	S:S:G650	1.68	No	No	0	5	3
2123	S:S:A668	S:S:T703	1.68	No	Yes	0	9	7
2124	S:S:A669	S:S:T703	1.68	No	Yes	0	7	7
2125	S:S:M839	S:S:P840	1.68	No	No	0	3	9
2126	R:R:K65	R:R:P66	1.67	No	No	0	1	1
2127	R:R:K785	R:R:P786	1.67	No	No	0	9	5
2128	S:S:K580	S:S:P647	1.67	No	No	0	6	9
2129	A:A:E216	A:A:G217	1.64	No	No	0	8	6
2130	B:B:G141	B:B:Q176	1.64	No	No	0	5	4
2131	B:B:E226	B:B:G224	1.64	No	No	0	3	6
2132	B:B:E260	B:B:G224	1.64	No	No	0	6	6
2133	R:R:L96	R:R:P97	1.64	No	No	0	9	8
2134	R:R:L515	R:R:P516	1.64	No	Yes	0	4	8
2135	R:R:G527	R:R:Q551	1.64	No	No	0	9	8
2136	R:R:L735	R:R:P566	1.64	Yes	No	0	6	8
2137	R:R:G660	R:R:Q710	1.64	No	No	0	6	9
2138	A:A:N294	A:A:P282	1.63	No	No	0	4	5
2139	R:R:N98	R:R:P97	1.63	No	No	0	8	8
2140	R:R:N461	R:R:P462	1.63	Yes	No	0	5	1
2141	R:R:S687	R:R:S689	1.63	No	No	0	4	5
2142	S:S:N461	S:S:P462	1.63	Yes	No	0	5	1
2143	S:S:S749	S:S:S752	1.63	No	No	0	8	6
2144	A:A:C325	A:A:K330	1.62	No	No	0	7	4
2145	B:B:S97	B:B:V100	1.62	No	No	0	8	9
2146	B:B:A140	B:B:I120	1.62	No	No	0	5	6
2147	R:R:A85	R:R:I410	1.62	No	No	0	8	7
2148	R:R:A300	R:R:I269	1.62	No	No	0	4	4
2149	R:R:A588	R:R:I644	1.62	No	Yes	0	8	8
2150	S:S:C67	S:S:K65	1.62	No	No	0	9	1
2151	S:S:S242	S:S:V210	1.62	No	Yes	0	7	6
2152	S:S:S242	S:S:V248	1.62	No	No	0	7	7
2153	S:S:A300	S:S:I269	1.62	No	Yes	0	4	4
2154	S:S:S829	S:S:V826	1.62	No	Yes	0	9	8
2155	A:A:A235	A:A:M240	1.61	No	No	0	5	6
2156	B:B:D153	B:B:P107	1.61	No	No	0	5	6
2157	R:R:D439	R:R:P440	1.61	No	No	0	1	3
2158	R:R:D736	R:R:P737	1.61	No	No	0	3	5
2159	S:S:D721	S:S:P722	1.61	Yes	No	0	6	7
2160	A:A:S326	A:A:T327	1.6	No	No	0	9	9
2161	R:R:V716	R:R:V720	1.6	No	No	0	4	4
2162	S:S:S253	S:S:T223	1.6	No	No	0	4	5
2163	S:S:V605	S:S:V842	1.6	No	No	0	6	8
2164	S:S:V765	S:S:V769	1.6	No	No	0	4	5
2165	R:R:C372	R:R:L374	1.59	No	No	0	8	3
2166	S:S:T50	S:S:V150	1.59	No	No	0	4	5
2167	S:S:G433	S:S:H424	1.59	No	No	0	3	5
2168	S:S:T768	S:S:V769	1.59	No	No	0	8	5
2169	R:R:A215	R:R:L499	1.58	No	No	45	5	7
2170	R:R:A215	R:R:L501	1.58	No	No	45	5	7
2171	R:R:A363	R:R:L353	1.58	No	No	0	3	6
2172	S:S:A215	S:S:L499	1.58	No	Yes	0	5	7
2173	S:S:A363	S:S:L353	1.58	No	No	0	3	6
2174	S:S:A487	S:S:L482	1.58	No	No	0	3	3
2175	A:A:C325	A:A:N331	1.57	No	No	0	7	8
2176	B:B:T179	B:B:T181	1.57	No	No	0	4	2
2177	S:S:C538	S:S:N219	1.57	No	No	0	9	6
2178	S:S:E646	S:S:P647	1.57	No	No	0	5	9
2179	A:A:A12	B:B:N88	1.56	No	No	0	4	7
2180	A:A:A226	A:A:N269	1.56	No	Yes	0	8	9
2181	R:R:A784	R:R:N782	1.56	No	No	0	9	9
2182	A:A:I285	A:A:S281	1.55	No	No	0	3	7
2183	R:R:I657	R:R:S653	1.55	No	No	0	5	5
2184	R:R:A812	R:R:D813	1.54	No	No	0	3	4
2185	R:R:C557	R:R:Q551	1.53	No	No	0	9	8
2186	R:R:H848	R:R:P849	1.53	No	No	0	7	8
2187	S:S:C524	S:S:Q525	1.53	No	Yes	58	9	1
2188	S:S:C542	S:S:Q525	1.53	No	Yes	58	9	1
2189	S:S:C557	S:S:Q551	1.53	No	No	0	9	8
2190	A:A:K17	A:A:V13	1.52	No	No	0	4	2
2191	A:A:C351	A:A:E350	1.52	Yes	No	0	4	4
2192	R:R:K373	R:R:V385	1.52	No	No	0	4	1
2193	R:R:M761	R:R:V765	1.52	No	No	0	6	4
2194	R:R:I772	R:R:T768	1.52	No	No	0	8	8
2195	R:R:K773	R:R:V769	1.52	No	No	0	7	5
2196	R:R:Q810	S:S:A812	1.52	No	No	0	8	3
2197	S:S:K745	S:S:V726	1.52	Yes	No	0	7	3
2198	S:S:I772	S:S:T768	1.52	No	No	0	8	8
2199	R:R:F84	R:R:G343	1.51	No	No	0	7	5
2200	R:R:A363	R:R:E364	1.51	No	No	0	3	5
2201	A:A:K349	A:A:T316	1.5	No	No	0	4	3
2202	R:R:G61	R:R:R111	1.5	No	No	0	2	5
2203	R:R:G343	R:R:R342	1.5	No	No	0	5	4
2204	R:R:G430	R:R:R431	1.5	No	No	0	4	3
2205	R:R:G776	R:R:R775	1.5	No	No	0	7	9
2206	S:S:K619	S:S:T615	1.5	No	No	0	7	9
2207	S:S:G622	S:S:R623	1.5	No	Yes	0	9	8
2208	S:S:L654	S:S:S653	1.5	No	No	0	5	5
2209	S:S:G742	S:S:R741	1.5	No	No	0	7	5
2210	A:A:L234	A:A:V233	1.49	No	No	0	8	4
2211	R:R:L700	R:R:V628	1.49	No	No	0	5	6
2212	S:S:L846	S:S:V842	1.49	No	No	0	6	8
2213	R:R:N98	R:R:V432	1.48	No	No	0	8	3
2214	A:A:D9	A:A:S6	1.47	No	No	0	4	8
2215	B:B:L152	B:B:T196	1.47	Yes	No	0	3	1
2216	R:R:D721	R:R:S749	1.47	Yes	No	0	6	8
2217	S:S:D485	S:S:S486	1.47	No	No	0	4	4
2218	S:S:I617	S:S:I844	1.47	No	No	0	7	8
2219	S:S:L642	S:S:T651	1.47	No	No	0	5	6
2220	S:S:D747	S:S:S723	1.47	No	No	0	5	8
2221	R:R:N466	R:R:T464	1.46	No	No	0	7	3
2222	R:R:I503	R:R:M506	1.46	No	No	0	4	7
2223	R:R:N569	R:R:T571	1.46	No	No	0	4	6
2224	R:R:D721	R:R:V720	1.46	Yes	No	0	6	4
2225	S:S:N454	S:S:T464	1.46	No	No	0	5	3
2226	R:R:F739	R:R:P737	1.44	No	No	0	3	5
2227	S:S:E63	S:S:S62	1.44	No	No	0	1	1
2228	B:B:I43	B:B:L284	1.43	No	Yes	0	3	5
2229	R:R:I318	R:R:L322	1.43	No	No	0	4	3
2230	R:R:I578	R:R:L744	1.43	No	No	0	5	7
2231	R:R:I714	R:R:L756	1.43	No	No	0	6	7
2232	A:A:I278	A:A:N294	1.42	No	No	0	6	4
2233	A:A:E261	A:A:T262	1.41	No	No	0	4	8
2234	B:B:L261	B:B:M262	1.41	No	No	0	5	4
2235	R:R:E274	R:R:T275	1.41	No	No	0	4	3
2236	R:R:K387	R:R:L374	1.41	No	No	0	1	3
2237	S:S:E568	S:S:T567	1.41	No	No	0	1	7
2238	S:S:G584	S:S:W583	1.41	No	No	0	4	5
2239	A:A:K209	A:A:N256	1.4	No	No	0	8	8
2240	S:S:D266	S:S:I269	1.4	No	Yes	0	3	4
2241	S:S:K448	S:S:N452	1.4	No	No	0	3	4
2242	S:S:C715	S:S:F718	1.4	No	Yes	0	3	7
2243	A:A:D229	A:A:M243	1.39	No	No	0	8	8
2244	A:A:P288	A:A:Y287	1.39	No	Yes	0	6	8
2245	B:B:H54	B:B:S334	1.39	Yes	No	0	9	4
2246	G:G:D36	G:G:M38	1.39	No	No	0	5	4
2247	R:R:A638	R:R:F658	1.39	No	Yes	0	6	6
2248	S:S:H305	S:S:S276	1.39	Yes	No	0	3	7
2249	S:S:P561	S:S:Y562	1.39	No	No	0	4	3
2250	A:A:A12	A:A:R15	1.38	No	No	0	4	4
2251	R:R:A125	R:R:R104	1.38	No	Yes	0	4	5
2252	R:R:E401	R:R:I318	1.37	No	No	0	5	4
2253	B:B:M45	B:B:Q44	1.36	No	No	0	4	4
2254	S:S:N90	S:S:N91	1.36	No	No	0	9	5
2255	R:R:D87	R:R:N91	1.35	No	No	0	7	5
2256	R:R:E488	R:R:K490	1.35	No	No	0	4	5
2257	S:S:D92	S:S:D94	1.33	No	No	0	7	3
2258	R:R:R351	R:R:S350	1.32	Yes	No	0	5	4
2259	R:R:F593	R:R:V596	1.31	No	No	0	2	3
2260	R:R:F641	R:R:V596	1.31	No	No	0	7	3
2261	S:S:H371	S:S:K386	1.31	No	No	0	3	3
2262	S:S:C755	S:S:W717	1.31	No	Yes	0	4	8
2263	S:S:F729	S:S:V743	1.31	No	No	0	4	6
2264	R:R:A331	R:R:W308	1.3	No	Yes	0	7	7
2265	R:R:A331	R:R:W314	1.3	No	Yes	0	7	7
2266	S:S:D245	S:S:E244	1.3	No	No	0	4	4
2267	S:S:A331	S:S:W308	1.3	No	Yes	0	7	7
2268	A:A:R313	A:A:T316	1.29	No	No	0	4	3
2269	R:R:E401	R:R:E73	1.27	No	Yes	0	5	2
2270	R:R:E227	S:S:E236	1.27	No	No	0	7	5
2271	R:R:E401	R:R:Q402	1.27	No	Yes	0	5	6
2272	R:R:E850	R:R:Q851	1.27	No	No	0	6	4
2273	S:S:E259	S:S:E63	1.27	No	No	0	3	1
2274	S:S:E364	S:S:E367	1.27	Yes	No	0	5	6
2275	S:S:E682	S:S:Q683	1.27	No	No	0	6	5
2276	R:R:I492	R:R:R505	1.25	Yes	No	0	7	3
2277	R:R:T556	R:R:Y555	1.25	No	No	0	4	3
2278	S:S:I772	S:S:R775	1.25	No	No	0	8	9
2279	A:A:N22	A:A:R21	1.21	No	No	0	4	4
2280	S:S:K531	S:S:Y555	1.19	No	No	0	6	3
2281	S:S:L709	S:S:Y759	1.17	No	Yes	0	5	8
2282	A:A:E25	A:A:R21	1.16	No	No	0	4	4
2283	R:R:E568	R:R:R738	1.16	No	No	0	1	4
2284	R:R:L751	R:R:W717	1.14	No	No	0	3	8
2285	A:A:R205	A:A:R208	1.07	No	No	0	9	9
2286	R:R:F693	R:R:R692	1.07	No	No	0	5	5
2287	R:R:R738	R:R:Y550	1.03	No	Yes	0	4	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:L39	5.94	4	0	9
2	A:A:K46	5.49	4	0	9
3	A:A:F189	9.13	4	16	9
4	A:A:F196	6.73833	6	0	7
5	A:A:K197	9.16	4	10	7
6	A:A:M198	4.805	4	0	7
7	A:A:F199	9.018	5	10	6
8	A:A:Q204	4.7675	4	10	9
9	A:A:K210	4.68	4	33	9
10	A:A:W211	5.315	4	0	9
11	A:A:F215	8.2125	4	10	9
12	A:A:Y230	7.746	5	0	9
13	A:A:F250	8.69833	6	8	9
14	A:A:W258	6.46	4	21	5
15	A:A:F259	6.5225	4	0	9
16	A:A:I264	5.3375	4	8	6
17	A:A:L266	6.04	4	8	9
18	A:A:F267	7.21143	7	32	9
19	A:A:N269	5.685	4	31	9
20	A:A:L283	5.11	4	0	7
21	A:A:Y287	7.92	8	34	8
22	A:A:Y302	9.83	4	34	6
23	A:A:F307	7.466	5	8	8
24	A:A:I319	7.56	4	8	6
25	A:A:Y320	7.716	5	25	8
26	A:A:V332	4.35	4	16	7
27	A:A:F334	11.715	4	0	4
28	A:A:K345	8.74	4	25	5
29	A:A:L348	5.5925	4	6	8
30	A:A:C351	3.88	4	0	4
31	B:B:L51	7.0375	4	0	9
32	B:B:H54	5.956	5	0	9
33	B:B:Y59	11.2225	4	21	8
34	B:B:I80	6.2675	4	30	8
35	B:B:W82	9.8	4	30	9
36	B:B:K89	7.77667	6	30	9
37	B:B:H91	7.0775	4	26	5
38	B:B:I93	6.84	4	0	7
39	B:B:W99	8.84833	6	10	9
40	B:B:Y105	6.00571	7	26	6
41	B:B:Y111	6.9975	4	0	4
42	B:B:L117	4.445	4	10	9
43	B:B:I123	4.025	4	0	6
44	B:B:Y124	5.225	6	0	6
45	B:B:N125	4.73	4	0	4
46	B:B:L139	9.52	4	0	9
47	B:B:Y145	6.79	6	0	8
48	B:B:F151	4.228	5	0	9
49	B:B:L152	4.2125	4	0	3
50	B:B:T159	6.714	5	14	9
51	B:B:D163	4.8925	4	0	9
52	B:B:W169	12.852	5	14	8
53	B:B:D170	6.44	4	7	9
54	B:B:F180	7.434	5	7	7
55	B:B:H183	8.224	5	7	9
56	B:B:K209	9.98	4	7	6
57	B:B:W211	9.132	5	7	8
58	B:B:F222	4.505	4	11	8
59	B:B:H225	7.975	4	11	9
60	B:B:F234	4.095	4	0	5
61	B:B:F235	7.804	5	0	6
62	B:B:N237	9.8425	4	0	5
63	B:B:F241	6.82167	6	11	6
64	B:B:T249	4.585	4	11	6
65	B:B:R251	7.83	5	11	8
66	B:B:F253	7.5675	4	11	6
67	B:B:F278	7.115	4	0	7
68	B:B:L284	3.2625	4	38	5
69	B:B:Y289	6.93429	7	27	7
70	B:B:W297	8.815	4	27	8
71	B:B:M325	4.5025	4	37	5
72	B:B:W332	11.7529	7	21	9
73	B:B:D333	9.835	4	17	9
74	B:B:K337	9.688	5	17	6
75	B:B:W339	9.098	5	17	9
76	L:L:?1	8.84375	8	1	0
77	M:M:?1	9.75375	8	3	0
78	R:R:I49	5.4875	4	0	6
79	R:R:F55	6.372	5	1	9
80	R:R:V57	7.17	4	1	6
81	R:R:H58	6.968	5	1	8
82	R:R:K72	9.395	4	1	4
83	R:R:E73	5.168	5	1	2
84	R:R:K74	7.41714	7	1	5
85	R:R:H77	7.995	4	1	6
86	R:R:R78	8.40167	6	1	4
87	R:R:E80	6.15167	6	1	8
88	R:R:L95	5.0175	4	0	7
89	R:R:I99	5.4425	4	0	5
90	R:R:L101	5.2525	4	0	9
91	R:R:R104	4.25	4	0	5
92	R:R:D107	7.8325	4	1	9
93	R:R:C109	6.675	4	1	7
94	R:R:D112	8.7375	4	2	4
95	R:R:L116	5.9425	4	2	5
96	R:R:F122	6.26	4	39	5
97	R:R:S157	7.1425	4	1	5
98	R:R:S159	6.3025	4	1	9
99	R:R:V161	3.6425	4	0	4
100	R:R:M164	7.57	4	2	5
101	R:R:L171	5.295	4	0	5
102	R:R:P175	4.42	4	0	8
103	R:R:Q176	7.59	4	0	8
104	R:R:Y179	9.01	4	1	8
105	R:R:T182	5.8	4	1	8
106	R:R:L186	9.1925	4	40	8
107	R:R:F194	7.054	5	0	7
108	R:R:F195	9.67	5	40	8
109	R:R:P200	6.51167	6	1	7
110	R:R:D202	6.84333	6	1	8
111	R:R:Q205	7.688	5	1	9
112	R:R:Q207	7.6525	4	1	4
113	R:R:W218	7.27286	7	15	9
114	R:R:Y220	5.772	5	0	9
115	R:R:Y230	8.2775	8	1	7
116	R:R:E264	6.6	4	0	3
117	R:R:F265	6.782	5	18	4
118	R:R:L272	5.675	4	9	8
119	R:R:V281	4.865	4	9	6
120	R:R:F284	5.94714	7	1	8
121	R:R:D289	6.68833	6	18	4
122	R:R:R292	7.785	4	18	1
123	R:R:L294	7.09	4	9	5
124	R:R:H305	10.7525	4	9	3
125	R:R:F306	8.548	5	9	7
126	R:R:F307	6.6475	4	15	7
127	R:R:W308	5.9	6	9	7
128	R:R:D312	6.9675	4	1	8
129	R:R:W314	4.68625	8	1	7
130	R:R:V327	6.928	5	9	3
131	R:R:P336	7.145	6	1	5
132	R:R:F348	7.34	5	1	7
133	R:R:R351	9.166	5	1	5
134	R:R:N359	6.745	4	1	7
135	R:R:W361	7.702	5	1	5
136	R:R:F362	8.41	4	1	5
137	R:R:F365	9.76667	6	1	6
138	R:R:N369	10.22	4	1	3
139	R:R:F370	10.748	5	1	8
140	R:R:I394	5.6175	4	1	5
141	R:R:Y400	5.5575	4	1	5
142	R:R:Q402	4.994	5	28	6
143	R:R:E403	7.8675	4	1	5
144	R:R:K405	7.7225	4	1	4
145	R:R:Q407	6.16	4	42	7
146	R:R:F408	6.305	4	1	7
147	R:R:H424	4.595	4	44	5
148	R:R:C428	4.7	5	44	7
149	R:R:Q445	5.3375	4	43	6
150	R:R:Y449	8.736	5	43	4
151	R:R:F455	6.23	5	0	9
152	R:R:N461	4.0775	4	42	5
153	R:R:N468	6.865	4	41	7
154	R:R:D470	10.6325	4	41	7
155	R:R:Y475	8.515	6	1	8
156	R:R:Q479	8.888	5	15	8
157	R:R:Y489	9.015	4	1	5
158	R:R:I492	5.2975	4	15	7
159	R:R:W495	6.53	5	1	5
160	R:R:W508	11.0225	4	15	8
161	R:R:P516	7.9575	4	15	8
162	R:R:R529	10.1175	4	46	6
163	R:R:Y550	13.6575	4	0	7
164	R:R:D563	6.1025	4	22	6
165	R:R:M564	8.8875	4	22	5
166	R:R:K580	4.0325	4	0	6
167	R:R:P591	3.895	4	0	8
168	R:R:T615	5.13333	6	0	9
169	R:R:I633	5.3225	4	0	9
170	R:R:Y637	6.728	5	0	8
171	R:R:I644	4.4475	4	0	8
172	R:R:P647	4.392	5	0	9
173	R:R:R655	6.685	4	0	8
174	R:R:F658	5.684	5	48	6
175	R:R:Y667	6.4775	4	0	6
176	R:R:T672	4.8775	4	6	7
177	R:R:R676	7.57286	7	6	8
178	R:R:R679	7.782	5	6	7
179	R:R:I680	4.64	5	6	9
180	R:R:F681	6.41143	7	6	9
181	R:R:Q683	7.975	4	0	5
182	R:R:P691	7.125	4	6	7
183	R:R:I694	4.93	5	6	7
184	R:R:T703	3.855	4	6	7
185	R:R:D721	4.38	5	50	6
186	R:R:L735	5.8225	4	47	6
187	R:R:R741	14.1775	4	47	5
188	R:R:V743	5.945	4	0	6
189	R:R:Y759	7.63	4	49	8
190	R:R:V777	6.775	4	6	8
191	R:R:F781	6.658	5	6	9
192	R:R:I787	5.815	4	0	9
193	R:R:Y792	6.35	5	5	9
194	R:R:F801	8.45	7	51	9
195	R:R:F805	12.88	5	0	8
196	R:R:Y838	6.16833	6	12	9
197	R:R:K841	4.8475	4	0	9
198	R:R:L846	4.6575	4	12	6
199	S:S:F55	7.2225	4	3	9
200	S:S:H58	5.616	5	4	8
201	S:S:K74	11.454	5	3	5
202	S:S:R78	8.78625	8	3	4
203	S:S:M82	4.855	4	3	8
204	S:S:I99	6.355	4	0	5
205	S:S:L101	5.566	5	0	9
206	S:S:D107	7.4325	4	4	9
207	S:S:C109	5.445	4	4	7
208	S:S:L116	4.8975	4	2	5
209	S:S:F122	5.0975	4	0	5
210	S:S:V151	5.18	4	53	4
211	S:S:S157	4.6525	4	3	5
212	S:S:V161	4.3475	4	0	4
213	S:S:M164	9.77	4	2	5
214	S:S:N167	4.848	5	2	5
215	S:S:I168	4.3975	4	2	5
216	S:S:R170	5.1725	4	0	5
217	S:S:Q176	5.834	5	2	8
218	S:S:Y179	8.0575	4	3	8
219	S:S:D185	5.405	4	2	4
220	S:S:L186	7.015	4	2	8
221	S:S:R191	9.876	5	2	5
222	S:S:Y192	8.726	5	2	5
223	S:S:F195	9.264	5	2	8
224	S:S:R197	7.602	5	2	9
225	S:S:P200	5.2675	4	0	7
226	S:S:D202	8.725	4	3	8
227	S:S:Y204	4.605	4	0	4
228	S:S:Q205	10.7175	4	3	9
229	S:S:Q207	7.1775	4	19	4
230	S:S:V210	4.425	4	0	6
231	S:S:D211	5.5425	4	19	5
232	S:S:R214	8.305	4	0	4
233	S:S:W218	9.974	5	0	9
234	S:S:Y220	5.75333	6	55	9
235	S:S:Y230	8.47	6	3	7
236	S:S:I256	4.938	5	24	5
237	S:S:F265	8.692	5	24	4
238	S:S:I269	2.51	4	0	4
239	S:S:L272	4.2725	4	23	8
240	S:S:V281	5.345	4	23	6
241	S:S:F284	6.3525	4	0	8
242	S:S:E287	8.16	4	0	3
243	S:S:D289	5.45	4	24	4
244	S:S:L294	5.01	4	0	5
245	S:S:H305	7.9575	4	0	3
246	S:S:F306	6.09167	6	23	7
247	S:S:W308	4.98	4	23	7
248	S:S:D312	9.925	4	3	8
249	S:S:W314	8.176	5	0	7
250	S:S:H323	10.25	4	0	1
251	S:S:E329	10.4825	4	56	5
252	S:S:P336	7.5275	4	0	5
253	S:S:F344	5.3875	4	0	8
254	S:S:R351	10.0075	4	0	5
255	S:S:R358	6.7275	4	0	4
256	S:S:N359	5.9775	4	4	7
257	S:S:W361	7.93	7	4	5
258	S:S:F362	6.69	4	4	5
259	S:S:E364	5.0175	4	4	5
260	S:S:W366	8.616	5	4	6
261	S:S:F370	11.0817	6	4	8
262	S:S:E392	10.7225	4	4	7
263	S:S:I394	5.3375	4	4	5
264	S:S:Q402	6.66	4	0	6
265	S:S:E403	7.155	6	3	5
266	S:S:K405	7.93667	6	3	4
267	S:S:F408	6.7025	4	0	7
268	S:S:M416	4.1925	4	0	6
269	S:S:Y449	6.19	4	0	4
270	S:S:I450	4.946	5	54	7
271	S:S:R451	5.865	4	0	6
272	S:S:F455	8.96	5	0	9
273	S:S:N461	2.82333	6	0	5
274	S:S:D470	7.245	4	2	7
275	S:S:Y475	8.62	5	0	8
276	S:S:Q479	5.3725	4	0	8
277	S:S:Y489	6.732	5	57	5
278	S:S:W495	6.428	5	19	5
279	S:S:L499	4.754	5	19	7
280	S:S:L501	4.945	4	19	7
281	S:S:Q525	6.526	5	58	1
282	S:S:Q549	4.795	4	59	7
283	S:S:Y550	7.27	4	60	7
284	S:S:C560	5.185	4	60	9
285	S:S:I576	8.3275	4	29	8
286	S:S:I599	3.19	4	0	6
287	S:S:R623	6.635	4	0	8
288	S:S:I633	3.548	5	62	9
289	S:S:Y637	5.02167	6	62	8
290	S:S:F641	4.615	4	0	7
291	S:S:T672	5.94	4	20	7
292	S:S:Q699	7.43	4	20	8
293	S:S:T703	3.1475	4	0	7
294	S:S:W717	7.455	4	0	8
295	S:S:F718	2.99	4	0	7
296	S:S:D721	4.5875	4	0	6
297	S:S:D731	8.295	4	29	6
298	S:S:K745	6.95	4	0	7
299	S:S:Y759	6.3775	4	0	8
300	S:S:M761	6.4275	4	0	6
301	S:S:V777	4.9125	4	0	8
302	S:S:E783	6.046	5	13	9
303	S:S:M791	4.6825	4	0	9
304	S:S:T793	5.4725	4	5	8
305	S:S:W798	8.6825	4	5	9
306	S:S:F801	7.2575	4	5	9
307	S:S:V826	3.5275	4	0	8
308	S:S:Y838	6.89571	7	13	9
309	S:S:K841	6.775	4	13	9
310	X:X:?1	8.068	10	5	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:M325	B:B:S67	14.1836	3.07	Yes	No	0	5	5
2	B:B:S67	B:B:T321	14.9284	9.59	No	No	0	5	7
3	B:B:T321	B:B:W63	15.673	13.34	No	No	0	7	7
4	B:B:L70	B:B:W63	17.1407	9.11	No	No	0	5	7
5	B:B:L70	B:B:W82	20.8569	5.69	No	Yes	0	5	9
6	B:B:I80	B:B:W82	33.4683	8.22	Yes	Yes	30	8	9
7	B:B:D76	B:B:K78	58.6831	8.3	No	No	0	9	8
8	B:B:D76	B:B:S74	55.719	8.83	No	No	0	9	9
9	B:B:H54	B:B:S74	54.2455	5.58	Yes	No	0	9	9
10	B:B:H54	B:B:I80	38.6577	5.3	Yes	Yes	0	9	8
11	B:B:K78	B:B:P94	61.626	10.04	No	No	0	8	5
12	B:B:I93	B:B:P94	62.3613	5.08	Yes	No	0	7	5
13	B:B:I93	B:B:L79	22.0198	4.28	Yes	No	0	7	7
14	B:B:L79	B:B:L95	22.2478	8.3	No	No	0	7	8
15	B:B:L95	B:B:V100	45.4404	7.45	No	No	0	8	9
16	B:B:S97	B:B:V100	68.8459	1.62	No	No	0	8	9
17	B:B:D118	B:B:S97	69.0447	8.83	No	No	0	9	8
18	B:B:D118	B:B:I120	69.2556	7	No	No	0	9	6
19	B:B:A140	B:B:I120	69.6864	1.62	No	No	0	5	6
20	B:B:A140	B:B:G141	69.9026	1.95	No	No	0	5	5
21	B:B:G141	B:B:Q176	70.1199	1.64	No	No	0	5	4
22	B:B:Q176	B:B:W169	70.3082	10.95	No	Yes	14	4	8
23	B:B:H142	B:B:W169	86.572	14.81	No	Yes	14	9	8
24	B:B:H142	B:B:S161	89.6575	12.55	No	No	0	9	9
25	B:B:D163	B:B:S161	90.4869	4.42	Yes	No	0	9	9
26	B:B:D163	B:B:G144	91.5197	5.03	Yes	No	0	9	8
27	B:B:G144	B:B:N119	91.7258	3.39	No	No	0	8	9
28	A:A:G183	B:B:N119	91.9316	5.09	No	No	0	8	9
29	A:A:G183	A:A:Q204	92.1374	6.58	No	Yes	0	8	9
30	A:A:I184	A:A:Q204	26.4934	4.12	No	Yes	10	8	9
31	A:A:I184	B:B:W99	26.5473	3.52	No	Yes	10	8	9
32	A:A:F199	B:B:W99	60.5147	18.04	Yes	Yes	10	6	9
33	A:A:F199	A:A:K197	100	8.69	Yes	Yes	10	6	7
34	A:A:E33	A:A:K197	99.6503	8.1	No	Yes	0	6	7
35	A:A:E33	A:A:K29	99.4974	2.7	No	No	0	6	2
36	B:B:I93	B:B:Y124	44.0721	7.25	Yes	Yes	0	7	6
37	B:B:L95	B:B:Y124	22.9808	3.52	No	Yes	0	8	6
38	B:B:C114	B:B:Y124	22.9806	5.38	No	Yes	0	8	6
39	B:B:C114	B:B:V100	23.2089	6.83	No	No	0	8	9
40	A:A:Q204	B:B:L117	30.5054	3.99	Yes	Yes	10	9	9
41	B:B:L117	B:B:W99	36.3201	4.56	Yes	Yes	10	9	9
42	A:A:Q204	A:A:W211	35.5461	4.38	Yes	Yes	0	9	9
43	A:A:F215	A:A:W211	33.0744	6.01	Yes	Yes	0	9	9
44	A:A:F199	A:A:F215	40.2361	7.5	Yes	Yes	10	6	9
45	A:A:K29	A:A:K32	99.4249	11.49	No	No	0	2	4
46	A:A:K32	R:R:S687	99.3523	3.06	No	No	0	4	4
47	R:R:Q683	R:R:S687	99.1333	7.22	Yes	No	0	5	4
48	A:A:N347	R:R:Q683	13.2309	3.96	No	Yes	0	7	5
49	A:A:N347	R:R:I680	13.1544	4.25	No	Yes	0	7	9
50	A:A:L348	R:R:I680	16.2463	4.28	Yes	Yes	6	8	9
51	A:A:L348	A:A:Y354	15.229	4.69	Yes	No	0	8	5
52	A:A:K345	A:A:Y354	14.8842	9.55	Yes	No	0	5	5
53	A:A:K345	A:A:Y320	12.9683	3.58	Yes	Yes	25	5	8
54	A:A:A338	A:A:Y320	12.2915	5.34	No	Yes	0	7	8
55	A:A:A338	A:A:F334	12.0548	4.16	No	Yes	0	7	4
56	A:A:F267	A:A:F334	11.3436	7.5	Yes	Yes	0	9	4
57	A:A:F215	A:A:L37	25.6692	7.31	Yes	No	0	9	9
58	A:A:L37	A:A:L39	16.0486	5.54	No	Yes	0	9	9
59	A:A:F223	A:A:L39	14.9769	10.96	No	Yes	0	9	9
60	B:B:L117	B:B:Y145	13.8047	3.52	Yes	Yes	0	9	8
61	B:B:M188	B:B:Y145	12.9127	10.78	No	Yes	0	8	8
62	A:A:I221	A:A:I264	12.016	5.89	No	Yes	0	7	6
63	A:A:F250	A:A:F307	16.2069	11.79	Yes	Yes	8	9	8
64	A:A:F307	A:A:M247	22.1509	6.22	Yes	No	0	8	6
65	A:A:M247	A:A:Y287	21.7804	7.18	No	Yes	0	6	8
66	R:R:P691	R:R:Q683	83.5838	15.79	Yes	Yes	0	7	5
67	R:R:P691	R:R:R679	81.3747	5.76	Yes	Yes	6	7	7
68	B:B:M188	B:B:N230	12.5008	5.61	No	No	0	8	9
69	B:B:D246	B:B:N230	12.4609	5.39	No	No	0	9	9
70	B:B:D246	B:B:G272	12.3461	5.03	No	No	0	9	4
71	B:B:C271	B:B:G272	12.2311	3.92	No	No	0	5	4
72	B:B:C271	B:B:Y289	12.0006	4.03	No	Yes	0	5	7
73	B:B:W297	B:B:Y289	10.5961	7.72	Yes	Yes	27	8	7
74	B:B:R49	G:G:E47	14.8963	11.63	No	No	0	7	3
75	B:B:N340	G:G:E47	11.9173	2.63	No	No	0	9	3
76	B:B:L51	B:B:W82	11.9242	12.53	Yes	Yes	0	9	9
77	B:B:L51	B:B:T87	10.422	4.42	Yes	No	0	9	5
78	B:B:I338	B:B:L51	11.9137	4.28	No	Yes	0	5	9
79	B:B:L336	B:B:L51	11.9054	6.92	No	Yes	0	7	9
80	B:B:I58	B:B:L336	12.6428	4.28	No	No	0	9	7
81	B:B:H54	B:B:I58	13.3836	11.93	Yes	No	0	9	9
82	B:B:L139	B:B:W169	17.4966	27.33	Yes	Yes	0	9	8
83	B:B:I123	B:B:L139	16.7173	4.28	Yes	Yes	0	6	9
84	B:B:I123	B:B:I171	12.6817	4.42	Yes	No	0	6	6
85	B:B:D170	B:B:T177	11.3	4.34	Yes	No	7	9	4
86	B:B:D170	B:B:N155	11.9511	5.39	Yes	No	7	9	3
87	R:R:N675	R:R:R679	87.8075	16.87	No	Yes	0	6	7
88	R:R:N675	R:R:Y770	87.7022	20.93	No	No	0	6	7
89	R:R:L671	R:R:Y770	87.4911	4.69	No	No	0	8	7
90	R:R:C767	R:R:L671	87.1732	6.35	No	No	0	8	8
91	R:R:C767	R:R:M791	80.14	4.86	No	No	0	8	9
92	R:R:M791	R:R:Y667	79.7881	5.99	No	Yes	0	9	6
93	R:R:M764	R:R:Y667	78.7232	3.59	No	Yes	0	8	6
94	R:R:C795	R:R:M764	78.6041	3.24	No	No	0	6	8
95	R:R:C795	R:R:L799	78.4847	3.17	No	No	0	6	6
96	R:R:L799	X:X:?1	78.3652	7.22	No	Yes	0	6	0
97	R:R:I802	X:X:?1	42.4577	5.32	No	Yes	0	7	0
98	R:R:F801	R:R:I802	42.2944	3.77	Yes	No	0	9	7
99	R:R:F801	R:R:S825	30.0926	7.93	Yes	No	0	9	8
100	R:R:S825	R:R:V797	29.9168	3.23	No	No	0	8	8
101	R:R:L828	R:R:V797	29.741	2.98	No	No	0	6	8
102	R:R:L594	R:R:L828	29.5649	2.77	No	No	0	4	6
103	R:R:L594	R:R:S827	29.3886	3	No	No	0	4	9
104	R:R:S827	R:R:T640	29.2122	4.8	No	No	0	9	7
105	R:R:T640	R:R:T823	28.3276	9.42	No	No	0	7	7
106	R:R:M643	R:R:T823	27.4387	3.01	No	No	0	7	7
107	R:R:M643	R:R:R655	27.2604	6.2	No	Yes	0	7	8
108	R:R:P647	R:R:R655	25.1075	7.21	Yes	Yes	0	9	8
109	R:R:K580	R:R:P647	23.8402	3.35	Yes	Yes	0	6	9
110	R:R:K580	R:R:L815	21.6483	7.05	Yes	No	0	6	6
111	R:R:L815	R:R:V743	21.2805	2.98	No	Yes	0	6	6
112	R:R:G742	R:R:V743	20.3582	1.84	No	Yes	0	7	6
113	R:R:G742	R:R:R741	20.1732	4.5	No	Yes	0	7	5
114	R:R:L735	R:R:R741	17.0998	8.5	Yes	Yes	47	6	5
115	R:R:L735	R:R:P566	15.1141	1.64	Yes	No	0	6	8
116	R:R:P566	R:R:Y550	14.9243	20.86	No	Yes	0	8	7
117	R:R:R570	R:R:Y550	12.2494	29.84	No	Yes	0	6	7
118	R:R:E528	R:R:R570	12.0571	10.47	No	No	0	5	6
119	R:R:E528	R:R:R529	11.479	9.3	No	Yes	0	5	6
120	R:R:P544	R:R:R529	10.3182	15.85	No	Yes	0	4	6
121	R:R:E543	R:R:P544	10.1242	6.29	No	No	0	4	4
122	R:R:C767	R:R:L670	12.2494	3.17	No	No	0	8	7
123	R:R:I787	R:R:L670	12.0571	11.42	Yes	No	0	9	7
124	R:R:E783	R:R:I787	11.479	6.83	No	Yes	0	9	9
125	R:R:E783	R:R:K841	11.0928	4.05	No	Yes	0	9	9
126	S:S:L828	X:X:?1	37.3183	4.13	No	Yes	5	6	0
127	R:R:Y792	S:S:L828	36.7783	5.86	Yes	No	5	9	6
128	R:R:Y792	S:S:T793	36.2711	3.75	Yes	Yes	5	9	8
129	R:R:F789	S:S:T793	24.5545	3.89	No	Yes	5	9	8
130	R:R:F789	S:S:F789	24.1816	13.93	No	No	5	9	9
131	S:S:F789	S:S:K785	24.0111	12.41	No	No	0	9	9
132	S:S:K785	S:S:P786	23.4662	5.02	No	No	0	9	5
133	S:S:E783	S:S:P786	23.2842	3.14	Yes	No	0	9	5
134	S:S:E783	S:S:K841	21.0128	9.45	Yes	Yes	13	9	9
135	S:S:K841	S:S:Y838	18.589	3.58	Yes	Yes	13	9	9
136	S:S:L629	S:S:Y838	16.242	5.86	No	Yes	0	8	9
137	S:S:L629	S:S:S666	16.0533	3	No	No	0	8	7
138	S:S:I633	S:S:S666	15.8645	3.1	Yes	No	0	9	7
139	S:S:I633	S:S:Y637	15.1009	3.63	Yes	Yes	62	9	8
140	S:S:S827	S:S:Y637	13.0114	5.09	No	Yes	0	9	8
141	S:S:S827	S:S:T640	12.2441	7.99	No	No	0	9	7
142	S:S:T640	S:S:T823	12.0519	4.71	No	No	0	7	7
143	S:S:M643	S:S:T823	11.8594	4.52	No	No	0	7	7
144	S:S:M643	S:S:R655	11.474	6.2	No	No	0	7	8
145	S:S:T790	S:S:T793	13.0114	3.14	No	Yes	0	9	8
146	S:S:M791	S:S:T790	12.8199	3.01	Yes	No	0	9	9
147	S:S:C767	S:S:M791	10.1198	6.48	No	Yes	0	8	9
148	B:B:I171	B:B:N155	12.4205	5.66	No	No	0	6	3
149	L:L:?1	R:R:Y230	13.2211	31.82	Yes	Yes	1	0	7
150	R:R:F284	R:R:Y230	37.534	4.13	Yes	Yes	1	8	7
151	R:R:F284	R:R:V235	47.3701	3.93	Yes	No	0	8	5
152	R:R:T223	R:R:V235	47.5251	4.76	No	No	0	5	5
153	R:R:I250	R:R:T223	47.6036	4.56	No	No	0	6	5
154	R:R:I239	R:R:I250	47.6468	5.89	No	No	0	4	6
155	R:R:I239	R:R:R243	47.6941	3.76	No	No	0	4	3
156	R:R:R243	S:S:R271	47.7894	15.99	No	No	0	3	3
157	S:S:R271	S:S:V254	47.9816	6.54	No	No	0	3	5
158	S:S:V224	S:S:V254	44.7513	4.81	No	No	0	5	5
159	S:S:I283	S:S:V224	40.9495	4.61	No	No	0	5	5
160	S:S:I283	S:S:W314	45.2707	5.87	No	Yes	0	5	7
161	S:S:P320	S:S:W314	47.0501	8.11	No	Yes	0	5	7
162	S:S:E287	S:S:P320	47.1958	9.43	Yes	No	0	3	5
163	S:S:E287	S:S:K74	21.1795	13.5	Yes	Yes	0	3	5
164	S:S:E287	S:S:S313	14.5141	4.31	Yes	No	0	3	6
165	S:S:E287	S:S:K317	11.6602	5.4	Yes	No	0	3	6
166	M:M:?1	S:S:S159	12.8717	3.82	Yes	No	3	0	9
167	M:M:?1	S:S:K405	11.1341	7.18	Yes	Yes	3	0	4
168	R:R:S159	R:R:S181	16.4037	6.52	Yes	No	0	9	8
169	L:L:?1	R:R:R78	13.4592	5.15	Yes	Yes	1	0	4
170	R:R:E403	R:R:R78	14.1627	6.98	Yes	Yes	1	5	4
171	R:R:F408	R:R:K405	13.356	6.2	Yes	Yes	1	7	4
172	R:R:F408	R:R:V198	16.9481	2.62	Yes	No	0	7	9
173	R:R:F465	R:R:V198	16.8157	2.62	No	No	0	8	9
174	R:R:F455	R:R:H418	16.3319	13.58	Yes	No	0	9	6
175	R:R:H418	R:R:L95	16.234	6.43	No	Yes	0	6	7
176	R:R:I89	R:R:L95	15.7009	5.71	No	Yes	0	9	7
177	R:R:I89	R:R:L101	15.5319	4.28	No	Yes	0	9	9
178	R:R:I49	R:R:L101	13.085	5.71	Yes	Yes	0	6	9
179	R:R:I49	R:R:L420	12.9543	5.71	Yes	No	0	6	8
180	R:R:L420	R:R:L446	12.9299	4.15	No	No	0	8	6
181	R:R:L446	R:R:P175	12.9064	6.57	No	Yes	0	6	8
182	R:R:F194	R:R:P175	12.7172	4.33	Yes	Yes	0	7	8
183	R:R:D193	R:R:F194	12.5475	9.55	No	Yes	0	6	7
184	R:R:D193	R:R:R170	12.5239	19.06	No	No	0	6	5
185	R:R:L171	R:R:R170	12.4813	4.86	Yes	No	0	5	5
186	R:R:L171	S:S:L116	11.867	4.15	Yes	Yes	0	5	5
187	R:R:S313	R:R:W314	23.3224	6.18	No	Yes	1	6	7
188	S:S:S159	S:S:S181	17.2692	4.89	No	No	0	9	8
189	S:S:S162	S:S:S181	11.2682	6.52	No	No	0	7	8
190	S:S:F195	S:S:L186	11.9995	13.4	Yes	Yes	2	8	8
191	R:R:A331	R:R:W314	16.6939	1.3	No	Yes	0	7	7
192	R:R:A331	R:R:W308	16.5286	1.3	No	Yes	0	7	7
193	R:R:F306	R:R:W308	12.0088	14.03	Yes	Yes	9	7	7
194	S:S:F408	S:S:K405	21.5404	4.96	Yes	Yes	0	7	4
195	S:S:F408	S:S:Q407	14.0278	8.2	Yes	No	0	7	7
196	R:R:S159	R:R:Y230	11.9346	6.36	Yes	Yes	1	9	7
197	R:R:S313	R:R:Y230	16.0375	3.82	No	Yes	1	6	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
M:M:?1	S:S:K74	10.76	3	Yes	Yes	0	5	0	1
M:M:?1	S:S:R78	10.3	3	Yes	Yes	0	4	0	1
M:M:?1	S:S:S159	3.82	3	Yes	No	0	9	0	1
M:M:?1	S:S:A180	5.35	3	Yes	No	0	6	0	1
M:M:?1	S:S:Y230	26.84	3	Yes	Yes	0	7	0	1
M:M:?1	S:S:S313	10.19	3	Yes	No	0	6	0	1
M:M:?1	S:S:K317	3.59	3	Yes	No	0	6	0	1
M:M:?1	S:S:K405	7.18	3	Yes	Yes	0	4	0	1
S:S:K71	S:S:K74	10.06	0	No	Yes	5	5	2	1
S:S:K74	S:S:R78	14.85	3	Yes	Yes	5	4	1	1
S:S:E287	S:S:K74	13.5	0	Yes	Yes	3	5	2	1
S:S:E403	S:S:K74	8.1	3	Yes	Yes	5	5	2	1
S:S:R78	S:S:S157	3.95	3	Yes	Yes	4	5	1	2
S:S:R78	S:S:Y179	9.26	3	Yes	Yes	4	8	1	2
S:S:A180	S:S:R78	4.15	3	No	Yes	6	4	1	1
S:S:E403	S:S:R78	13.96	3	Yes	Yes	5	4	2	1
S:S:K405	S:S:R78	9.9	3	Yes	Yes	4	4	1	1
S:S:R78	S:S:V409	3.92	3	Yes	No	4	7	1	2
S:S:S157	S:S:Y179	3.82	3	Yes	Yes	5	8	2	2
S:S:S159	S:S:S181	4.89	3	No	No	9	8	1	2
S:S:S159	S:S:Y230	5.09	3	No	Yes	9	7	1	1
S:S:V409	S:S:Y179	8.83	3	No	Yes	7	8	2	2
S:S:A180	S:S:K405	6.42	3	No	Yes	6	4	1	1
S:S:D202	S:S:Y230	6.9	3	Yes	Yes	8	7	2	1
S:S:G231	S:S:Y230	4.35	0	No	Yes	8	7	2	1
S:S:S311	S:S:Y230	3.82	0	No	Yes	8	7	2	1
S:S:S313	S:S:Y230	3.82	3	No	Yes	6	7	1	1
S:S:E287	S:S:S313	4.31	0	Yes	No	3	6	2	1
S:S:E287	S:S:K317	5.4	0	Yes	No	3	6	2	1
S:S:D312	S:S:K405	11.06	3	Yes	Yes	8	4	2	1
S:S:E403	S:S:K317	5.4	3	Yes	No	5	6	2	1
S:S:E403	S:S:K405	8.1	3	Yes	Yes	5	4	2	1
S:S:F408	S:S:K405	4.96	0	Yes	Yes	7	4	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
100.00	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
100.00	Single	6D35	Cholesterol	6D35-SMO-Cholesterol
100.00	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
100.00	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
100.00	Single	6UO8	SKF97541	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
100.00	Single	6UO9	SKF97541	6UO9-GABA_B1, GABA_B2-SKF97541
100.00	Single	6W2X	PubChem 5311042	6W2X-GABA_B1, GABA_B2-PubChem 5311042
100.00	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042
100.00	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042
100.00	Single	7C7Q	Baclofen	7C7Q-GABA_B1, GABA_B2-Baclofen-BHFF
100.00	Single	7C7S	CGP54626	7C7S-GABA_B1, GABA_B2-CGP54626
100.00	Single	7CUM	CGP54626	7CUM-GABA_B1, GABA_B2-CGP54626
100.00	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DGE	Quisqualate	7DGE-mGlu1; mGlu1-Quisqualate
100.00	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
100.00	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
100.00	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
100.00	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
100.00	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
100.00	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
100.00	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
100.00	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
100.00	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
100.00	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
100.00	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/β1/γ2
100.00	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/β1/γ2
100.00	Single	7EB2	Baclofen	7EB2-GABAB2; GABAB1-Baclofen-rac-BHFF-Gi1/β1/γ2
100.00	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
100.00	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
100.00	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
100.00	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
100.00	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
100.00	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
100.00	Single	7FIH	hCG	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
100.00	Single	7FII	hCG	7FII-LH-hCG-chim(NtGi1-Gs)/β1/γ2
100.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
100.00	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
100.00	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
100.00	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
100.00	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
100.00	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
100.00	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
100.00	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
100.00	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
100.00	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
100.00	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
100.00	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7T9N	M22 Fab	7T9N-TSH-M22 Fab-DPPC-Gs/β1/γ2
100.00	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
100.00	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
100.00	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
100.00	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
100.00	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
100.00	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
100.00	Single	7XW6	M22 Fab	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
100.00	Single	7XW7	K1-70	7XW7-TSH-K1-70
100.00	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
100.00	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
100.00	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
100.00	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
100.00	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
100.00	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
100.00	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
100.00	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
100.00	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
100.00	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
100.00	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
100.00	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
100.00	Single	8JD0	Glutamate	8JD0-mGlu2; mGlu3-Glutamate-NAM563
100.00	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
100.00	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
100.00	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
100.00	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
100.00	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-JNJ-40411813-Gi1/β1/γ2
100.00	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-JNJ-40411813-Gi1/β1/γ2
100.00	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
100.00	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
100.00	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
100.00	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
100.00	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-VU0364770-Gi3/β1/γ2
100.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
100.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
100.00	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine-chim(NtGi1-Gq)/β1/γ2
100.00	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
100.00	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
100.00	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
100.00	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
100.00	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
100.00	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
100.00	Single	8TQB	Ca; PAM VU6023326	8TQB-mGlu3; mGlu3-Ca; PAM VU6023326-Ca
100.00	Single	8TQB	Ca; PAM VU6023326	8TQB-mGlu3; mGlu3-Ca; PAM VU6023326-Ca
100.00	Single	8TR0	LY341495	8TR0-mGlu3; mGlu3-LY341495
100.00	Single	8TR0	LY341495	8TR0-mGlu3; mGlu3-LY341495
100.00	Single	8TR2	Ca; LY379268	8TR2-mGlu3; mGlu3-Ca; LY379268-Ca
100.00	Single	8TR2	Ca; LY379268	8TR2-mGlu3; mGlu3-Ca; LY379268-Ca
100.00	Single	8TRC	LY341495	8TRC-mGlu3; mGlu3-LY341495
100.00	Single	8TRC	LY341495	8TRC-mGlu3; mGlu3-LY341495
100.00	Single	8TRD	LY341495	8TRD-mGlu3; mGlu3-LY341495
100.00	Single	8TRD	LY341495	8TRD-mGlu3; mGlu3-LY341495
100.00	Single	8WG9	(2S)-2-amino-4-phosphonobutanoic acid	8WG9-mGlu4; mGlu2-(2S)-2-amino-4-phosphonobutanoic acid
100.00	Single	8WGB	Glutammate	8WGB-mGlu4; mGlu2-Glutammate-VU0155041-Gi3/β1/γ2
100.00	Single	8WGB	Glutammate	8WGB-mGlu4; mGlu2-Glutammate-VU0155041-Gi3/β1/γ2
100.00	Single	8WGC	LY379268	8WGC-mGlu4; mGlu2-LY379268
100.00	Single	8WGD	WAG; WA6	8WGD-mGlu4; mGlu2-WAG; WA6
100.00	Single	8WGD	WAG; WA6	8WGD-mGlu4; mGlu2-WAG; WA6
100.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
100.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
100.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
100.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
100.00	Single	8WVX	Norrin	8WVX-LGR4-Norrin
100.00	Single	8WVY	Norrin	8WVY-LGR4-Norrin
100.00	Single	8X0B	Quisqualate	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0B	Quisqualate	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0C	Quisqualate	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0C	Quisqualate	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0D	Quisqualate	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0D	Quisqualate	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0E	Quisqualate	8X0E-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0E	Quisqualate	8X0E-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0F	Quisqualate	8X0F-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0F	Quisqualate	8X0F-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0G	Quisqualate	8X0G-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0G	Quisqualate	8X0G-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0H	Quisqualate	8X0H-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0H	Quisqualate	8X0H-mGlu5; mGlu5-Quisqualate
100.00	Single	8XUM	R-spondin-2	8XUM-LGR4-R-spondin-2
100.00	Single	9ASB	Ca	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AVG	Ca	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
100.00	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
100.00	Single	9AVL	Ca	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
100.00	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
100.00	Single	9AVL	Ca	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
100.00	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
100.00	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
100.00	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
100.00	Single	9C1P	Ca	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
100.00	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
100.00	Single	9C1P	Ca	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
100.00	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
100.00	Single	9C2F	Ca	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
100.00	Single	9C2F	Ca; Ca; Tryptophan; '54149; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
100.00	Single	9C2F	Ca	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
100.00	Single	9C2F	Ca; Ca; Tryptophan; '54149; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
100.00	Single	9II2	Glutamate	9II2-mGlu3; mGlu3-Glutamate-Arrestin2
100.00	Single	9II2	Glutamate	9II2-mGlu3; mGlu3-Glutamate-Arrestin2
100.00	Single	9II3	Glutamate	9II3-mGlu3; mGlu3-Glutamate-Arrestin2
100.00	Single	9II3	Glutamate	9II3-mGlu3; mGlu3-Glutamate-Arrestin2
100.00	Single	9KHH	Norrin	9KHH-LGR4-Norrin
100.00	Single	9S37	NB21	9S37-LGR4-NB21
100.00	Single	9UTB	Sucralose	9UTB-TAS1R2; TAS1R3-Sucralose
50.00	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
50.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
50.00	Single	9ASB	Ca	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
50.00	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
50.00	Single	9AVG	Ca	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
50.00	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
50.00	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
50.00	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
33.33	Single	7KNU	Calcitonin gene-related peptide-1	7KNU-CT Like-Calcitonin gene-related peptide-1-RAMP1
33.33	Single	7T9M	CS-17 Antibody	7T9M-TSH-CS-17 Antibody
25.00	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
25.00	Single	7FIG	hCG	7FIG-LH-hCG-chim(NtGi1L-Gs)/β1/γ2
25.00	Single	7UTZ	TR1402	7UTZ-TSH-TR1402-DPPC-Gs/β1/γ2
25.00	Single	7XW5	TSH	7XW5-TSH-TSH-ML109-Gs/β1/γ2
25.00	Single	7ZI0	Cholesterol	7ZI0-SMO-SAG-Cholesterol
20.00	Single	5L7D	Cholesterol	5L7D-SMO-Cholesterol
20.00	Single	7T9I	TSH	7T9I-TSH-TSH-Gs/β1/γ2
20.00	Single	8HS2	Fab046	8HS2-GPR20-Fab046
20.00	Single	8I2G	Glycoprotein hormones alpha chain	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
20.00	Single	8X9S	5alpha-DHT	8X9S-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
20.00	Single	9IV2	5alpha-DHT	9IV2-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
16.67	Single	6XBM	5LWE	6XBM-SMO-5LWE-Gi1/β1/γ2
16.67	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Gi1/β1/γ2
16.67	Consensus	p2y_off	Orthosteric Ligand	p2y1_off
14.29	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
14.29	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
14.29	Single	8JEF	(3S)-3-hydroxyoctanoic acid	8JEF-HCA₃-(3S)-3-hydroxyoctanoic acid-Gi1/β1/γ2
14.29	Single	8JPS	CCL7	8JPS-ACKR1-CCL7
14.29	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
14.29	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
12.50	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
12.50	Single	6LI0	C17	6LI0-GPR52-C17
12.50	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/β1/γ2
12.50	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/β1/γ2
12.50	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab
12.50	Single	9B9Y	7DY	9B9Y-CB₁-7DY
12.50	Single	9E7R	GB88	9E7R-PAR2-GB88-chim(NtGi1L-Gs-CtGq)/β1/γ2
11.11	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
11.11	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
11.11	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
11.11	Single	5U09	Taranabant	5U09-CB₁-Taranabant
11.11	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/β1/γ2
11.11	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
11.11	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/β1/γ2
11.11	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
11.11	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
11.11	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/β1/γ2
11.11	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/β1/γ2
11.11	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/β1/γ2
11.11	Single	8HMP	C17	8HMP-GPR52-C17-Gs/β1/γ2
11.11	Single	8U4S	REGN7663-Fab	8U4S-CXCR4-REGN7663-Fab
11.11	Single	8U4T	REGN7663-Fab	8U4T-CXCR4-REGN7663-Fab
11.11	Single	8XXX	CXCL6	8XXX-CXCR2-CXCL6-Go/β1/γ2
11.11	Single	8YYW	Alpha-ketoglutarate	8YYW-Oxoglutarate-α-ketoglutarate-α-ketoglutarate-chim(Gi1-CtGq)/β1/γ2
11.11	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
11.11	Consensus	ccr6_on_gp	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
11.11	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
11.11	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
11.11	Consensus	p2y1_on	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
11.11	Consensus	s1p1_off	Orthosteric Ligand	3V2W-S1P₁-PubChem 51892645
10.00	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
10.00	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
10.00	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2
10.00	Single	7UTZ	DPPC	7UTZ-TSH-TR1402-DPPC-Gs/β1/γ2
10.00	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
10.00	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
10.00	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
10.00	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	9BA0	A1AKN	9BA0-CB₁-A1AKN
10.00	Single	9K0K	UTP	9K0K-P2Y₄-UTP-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	9K0X	ATP	9K0X-P2Y₂-ATP-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	9K20	ATP	9K20-P2Y₂-ATP-chim(NtGi1-Go)/β1/γ2
10.00	Single	9M2F	Neuropeptide FF	9M2F-NPFF1-Neuropeptide FF-Gi1/β1/γ2
10.00	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
10.00	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
10.00	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
10.00	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
10.00	Consensus	p2y1_on_gp	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
9.09	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
9.09	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
9.09	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
9.09	Single	6D27	CAY10471	6D27-DP₂-CAY10471
9.09	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/β1/γ2
9.09	Single	6XBM	5LWE	6XBM-SMO-5LWE-Gi1/β1/γ2
9.09	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
9.09	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
9.09	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/β1/γ2
9.09	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
9.09	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
9.09	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
9.09	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/β1/γ2
9.09	Single	7VIF	S-FTY720-P	7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2
9.09	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
9.09	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
9.09	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
9.09	Single	9IVG	GLP-1 (Truncated)	9IVG-GLP-1-GLP-1 (Truncated)-chim(NtGi1-Gs)/β1/γ2
9.09	Consensus	cxcr1_on_gp	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
9.09	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off paf_off lpl_off prostanoid_off leukotriene_off
9.09	Consensus	nucleotide_offon	Orthosteric Ligand	nucleotide_off nucleotide_on
9.09	Consensus	nucleotide_offon_gp	Orthosteric Ligand	nucleotide_on_gp nucleotide_off
8.33	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
8.33	Single	5C1M	BU72	5C1M-μ-BU72
8.33	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
8.33	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
8.33	Single	7BB7	AVP	7BB7-V₂-AVP-Gs/β1/γ2
8.33	Single	7C4S	S1P	7C4S-S1P₃-S1P
8.33	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/β1/γ2
8.33	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/β1/γ2
8.33	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
8.33	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/β1/γ2
8.33	Single	8ID4	Linoleic acid	8ID4-FFA4-Linoleic acid-Gi1/β1/γ2
8.33	Single	8YIC	SAR247799	8YIC-S1P₁-SAR247799-Gi1/β1/γ2
8.33	Single	8ZPT	PrRP20	8ZPT-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	8ZYT	Neurotensin peptide 8-13	8ZYT-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
8.33	Single	9B9Z	A1AKO	9B9Z-CB₁-A1AKO
8.33	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
8.33	Consensus	cxcr2_on_gp	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
8.33	Consensus	lpa1_on	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
8.33	Consensus	lpa1_on_gp	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
8.33	Consensus	s1p5_off	Orthosteric Ligand	7YXA-S1P₅-ONO-5430608
8.33	Consensus	s1p_off	Orthosteric Ligand	s1p1_off s1p5_off
7.69	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
7.69	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
7.69	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
7.69	Single	5V56	TC114	5V56-SMO-TC114
7.69	Single	5V57	TC114	5V57-SMO-TC114
7.69	Single	6OS1	TRV026	6OS1-AT₁-TRV026
7.69	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
7.69	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/β1/γ2
7.69	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
7.69	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
7.69	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/β1/γ1
7.69	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/β1/γ1
7.69	Single	7R0C	AVP	7R0C-V₂-AVP-Arrestin2
7.69	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
7.69	Single	7T9N	DPPC	7T9N-TSH-M22 Fab-DPPC-Gs/β1/γ2
7.69	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/β1/γ2
7.69	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/β1/γ2
7.69	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/β1/γ2
7.69	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/β1/γ2
7.69	Single	8E0G	BU72	8E0G-μ-BU72
7.69	Single	8FMZ	Neurotensin/Neuromedin-N	8FMZ-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.69	Single	8FN1	Neurotensin/Neuromedin-N	8FN1-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi1-Go)/β1/γ2
7.69	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/β1/γ2
7.69	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
7.69	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
7.69	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
7.69	Single	8JBG	Neurokinin-B	8JBG-NK₃-Neurokinin-B-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	8JZP	C5A anaphylatoxin	8JZP-C5a₁-C5A anaphylatoxin-Go/β1/γ2
7.69	Single	8WJX	ADP	8WJX-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
7.69	Single	8XX7	CXCL5	8XX7-CXCR2-CXCL5-Go/β1/γ2
7.69	Single	9AST	Lymphotactin	9AST-XCR1-Lymphotactin-Gi1/β1/γ2
7.69	Single	9IZG	NKP	9IZG-LPA₁-NKP-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Consensus	class-a_off	Orthosteric Ligand	sensory_off alicarboxylic_off amine_off lipid_off nucleotide_off peptide_off protein_off
7.69	Consensus	gi_lpa	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
7.69	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
7.69	Consensus	lpa_on_gp	Orthosteric Ligand	lpa1_on_gp
7.69	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Consensus	neurotensin_on	Orthosteric Ligand	nts1_on
7.69	Consensus	nts1_on	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
7.69	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
7.69	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
7.69	Consensus	s1p5_on_gp	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
7.14	Single	4GRV	Neurotensin-(8-13)	4GRV-NTS₁-Neurotensin-(8-13)
7.14	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
7.14	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
7.14	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
7.14	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
7.14	Single	6OS2	TRV026	6OS2-AT₁-TRV026
7.14	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/β1/γ2
7.14	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/β1/γ2
7.14	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
7.14	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
7.14	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
7.14	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
7.14	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
7.14	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
7.14	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Single	8JPB	Neurotensin-(8-13)	8JPB-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
7.14	Single	8JPC	Neurotensin-(8-13)	8JPC-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
7.14	Single	8T3Q	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3Q-FFA4-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.14	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/β1/γ2
7.14	Single	8XQJ	JN241	8XQJ-Apelin-JN241
7.14	Single	8XWA	CXCL1	8XWA-CXCR2-CXCL1
7.14	Single	8XWM	CXCL6	8XWM-CXCR2-CXCL6
7.14	Single	8XWS	CXCL5	8XWS-CXCR2-CXCL5
7.14	Single	8XX3	CXCL3	8XX3-CXCR2-CXCL3-Go/β1/γ2
7.14	Single	9IZH	LPA	9IZH-LPA₁-LPA-chim(NtGi2-G13)/β1/γ2
7.14	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
7.14	Consensus	ccr8_on	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
7.14	Consensus	cxcr_on	Orthosteric Ligand	cxcr3_on cxcr4_on cxcr1_on cxcr2_on
7.14	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_ffa gi_leukotriene gi_lpa gi_s1p
7.14	Consensus	gi_neurotensin	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
7.14	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
7.14	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
7.14	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
7.14	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
7.14	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
7.14	Consensus	mop_on	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
7.14	Consensus	mop_on_gp	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
7.14	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Consensus	neurotensin_on_gp	Orthosteric Ligand	nts1_on_gp
7.14	Consensus	nts1_on_gp	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
7.14	Consensus	s1p1_on	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
7.14	Consensus	s1p1_on_gp	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
7.14	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
6.67	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
6.67	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
6.67	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
6.67	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
6.67	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
6.67	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
6.67	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
6.67	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
6.67	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
6.67	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/β1/γ2
6.67	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/β1/γ2
6.67	Single	8FN0	Neurotensin/Neuromedin-N	8FN0-NTS₁-Neurotensin/Neuromedin-N-SBI-553-chim(NtGi1-Go)/β1/γ2
6.67	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
6.67	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-SBI-553
6.67	Single	8K4O	CXCL1	8K4O-KSHV-CXCL1-Gi1/β1/γ1
6.67	Single	8XVU	CXCL2	8XVU-CXCR2-CXCL2
6.67	Single	8XWF	CXCL3	8XWF-CXCR2-CXCL3
6.67	Single	8XWV	CXCL1	8XWV-CXCR2-CXCL1-Go/β1/γ2
6.67	Single	8XXH	CXCL2	8XXH-CXCR2-CXCL2-Go/β1/γ2
6.67	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
6.67	Single	9C0K	Exendin-4	9C0K-GLP-1-Exendin-4-Gs/β1/γ2
6.67	Single	9GE3	Lysophosphatidylinositol	9GE3-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
6.67	Single	9IZF	NKP	9IZF-LPA₁-NKP-Gi1/β1/γ2
6.67	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
6.67	Consensus	gi_s1p	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7EW3-S1P₃-S1P-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EW1-S1P₅-Siponimod-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
6.67	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
6.25	Single	5VBL	Apelin mimetic peptide agonist	5VBL-Apelin-Apelin mimetic peptide agonist
6.25	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
6.25	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
6.25	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
6.25	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/β1/γ2
6.25	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/β1/γ2
6.25	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
6.25	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
6.25	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
6.25	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/β1/γ2
6.25	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
6.25	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
6.25	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs
6.25	Single	8XQJ	JN241	8XQJ-Apelin-JN241
6.25	Single	8XX6	CXCL8	8XX6-CXCR2-CXCL8-Go/β1/γ2
6.25	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
6.25	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II 3OE0-CXCR4-CVX15 3OE6-CXCR4-IT1t
6.25	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
6.25	Consensus	s1p_on	Orthosteric Ligand	s1p1_on s1p3_on s1p5_on
6.25	Consensus	s1p_on_gp	Orthosteric Ligand	s1p1_on_gp s1p3_on_gp s1p5_on_gp
5.88	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
5.88	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
5.88	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/β1/γ2
5.88	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/β1/γ1
5.88	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
5.88	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
5.88	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
5.88	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
5.88	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
5.88	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
5.88	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
5.88	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Gi1/β1/γ2
5.88	Single	8WZ2	Orexigenic Neuropeptide QRFP	8WZ2-QRFP-Orexigenic Neuropeptide QRFP-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.88	Single	8XFT	R-spondin-2	8XFT-LGR4-R-spondin-2-ZNRF3
5.88	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
5.88	Single	8XWN	CXCL8	8XWN-CXCR2-CXCL8
5.88	Single	8Y69	R-spondin-2	8Y69-LGR4-R-spondin-2-ZNRF3
5.88	Single	8YWF	Retatrutide	8YWF-GLP-1-Retatrutide-chim(NtGi1-Gs)/β1/γ2
5.88	Single	9BUE	Cagrilintide	9BUE-CT-Cagrilintide-Gs/β1/γ2
5.88	Single	9L3Y	Retinoic acid receptor responder protein 2	9L3Y-CML2-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
5.88	Consensus	ccr1_on	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
5.88	Consensus	ccr1_on_gp	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
5.88	Consensus	chemokine_on	Orthosteric Ligand	ccr_on cxcr_on
5.88	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
5.88	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
5.88	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
5.88	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
5.88	Consensus	lpl_on_gp	Orthosteric Ligand	s1p_on_gp lpa_on_gp
5.88	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
5.88	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
5.56	Single	6DO1	Angiotensin-like peptide S1I8	6DO1-AT₁-Angiotensin-like peptide S1I8
5.56	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
5.56	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
5.56	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
5.56	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
5.56	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/β1/γ2
5.56	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/β1/γ2
5.56	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
5.56	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
5.56	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
5.56	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
5.56	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
5.56	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/β1/γ2
5.56	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
5.56	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/β1/γ2
5.56	Single	8Z7J	Agonistic antibody	8Z7J-Apelin-Agonistic antibody-Gi1/β1/γ2
5.56	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
5.56	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
5.56	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
5.56	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
5.56	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
5.26	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
5.26	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
5.26	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
5.26	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/β1/γ2; RAMP2
5.26	Single	7O7F	6P4-CCL5	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1
5.26	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
5.26	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
5.26	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
5.26	Single	8K6N	Pro-neuropeptide-Y	8K6N-Y₂-Pro-neuropeptide-Y-Gi2/β1/γ1
5.26	Single	8WKZ	SBL-MC-31	8WKZ-MC₄-SBL-MC-31
5.26	Single	8WVU	R-spondin-1	8WVU-LGR4-R-spondin-1-RNF43
5.26	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/β1/γ2
5.26	Single	8Y69	R-spondin-2	8Y69-LGR4-R-spondin-2-ZNRF3
5.26	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
5.26	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
5.26	Single	9M1O	Morphine-Modulating Neuropeptide B	9M1O-NPFF2-Morphine-Modulating Neuropeptide B-Gi1/β1/γ2
5.26	Single	9U4W	Gonadoliberin-1	9U4W-GnRH₁-Gonadoliberin-1-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.26	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
5.26	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
5.26	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
5.26	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
5.26	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
5.26	Consensus	ccr_on	Orthosteric Ligand	ccr6_on ccr8_on ccr2_on ccr1_on ccr5_on
5.26	Consensus	class-b1_class-b2_cons_on	Orthosteric Ligand	class-b1_on class-b2_on
5.26	Consensus	class-b1_class-b2_cons_on_gp	Orthosteric Ligand	class-b1_on_gp class-b2_on_gp
5.26	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
5.26	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
5.26	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
5.26	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
5.00	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
5.00	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/β1/γ2
5.00	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
5.00	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
5.00	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
5.00	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
5.00	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
5.00	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
5.00	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
5.00	Single	7YON	Peptide-YY(3-36)	7YON-Y₂-Peptide-YY(3-36)-Gi1/β1/γ2
5.00	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
5.00	Single	8XFP	R-spondin-2	8XFP-LGR4-R-spondin-2-ZNRF3
5.00	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/β1/γ2
5.00	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
5.00	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ2
5.00	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
5.00	Single	9BLC	Cagrilintide backbone (non-acylated)	9BLC-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
5.00	Single	9BUD	Cagrilintide	9BUD-CT-Cagrilintide-Gs/β1/γ2
5.00	Single	9EBO	GLP-1 (ACPC18)	9EBO-GLP-1-GLP-1 (ACPC18)-Gs/β1/γ2
5.00	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
5.00	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
5.00	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
5.00	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
5.00	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
5.00	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
5.00	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
5.00	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
5.00	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
5.00	Consensus	protein_offon	Orthosteric Ligand	protein_off protein_on
5.00	Consensus	protein_offon_gp	Orthosteric Ligand	protein_on_gp protein_off
5.00	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
5.00	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
5.00	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
5.00	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
5.00	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
5.00	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
4.76	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
4.76	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
4.76	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
4.76	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
4.76	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
4.76	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/β1/γ2
4.76	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
4.76	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
4.76	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
4.76	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
4.76	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.76	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
4.76	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
4.76	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
4.76	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
4.76	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/β1/γ2
4.76	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
4.76	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/β1/γ2
4.76	Single	8XQE	Apelin-13	8XQE-Apelin-Apelin-13-Gi1/β1/γ2
4.76	Single	8XVH	Endothelin-1	8XVH-ET_B-Endothelin-1-chim(Gs-CtGq)/β1/γ2
4.76	Single	8XVI	Endothelin-1	8XVI-ET_A-Endothelin-1-chim(Gs-CtGq)/β1/γ2
4.76	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	9JFY	hNPSF	9JFY-NPFF2-hNPSF-Gi1/β1/γ2
4.76	Consensus	calcitonin_on	Orthosteric Ligand	ctlike_on
4.76	Consensus	ccr_on_gp	Orthosteric Ligand	ccr6_on_gp ccr8_on_gp ccr2_on_gp ccr1_on_gp ccr5_on_gp
4.76	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
4.76	Consensus	chemokine_on_gp	Orthosteric Ligand	ccr_on_gp cxcr_on_gp
4.76	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
4.76	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
4.76	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2 6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
4.76	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
4.76	Consensus	pac_on	Orthosteric Ligand	pac1_on
4.76	Consensus	vpac1_on	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
4.76	Consensus	vpac_on	Orthosteric Ligand	vpac1_on vpac2_on
4.55	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
4.55	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
4.55	Single	6FJ3	PTH	6FJ3-PTH1-PTH
4.55	Single	6NBF	Long-Acting PTH Analog	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
4.55	Single	6NBI	Long-Acting PTH Analog	6NBI-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
4.55	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
4.55	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
4.55	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
4.55	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
4.55	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
4.55	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ2
4.55	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
4.55	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
4.55	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
4.55	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
4.55	Single	9BLB	Cagrilintide backbone (non-acylated)	9BLB-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
4.55	Single	9BLW	Cagrilintide backbone (non-acylated)	9BLW-CT (AMY1)-Cagrilintide backbone (non-acylated)-Gs/β1/γ2; RAMP1
4.55	Single	9BP3	Cagrilintide	9BP3-CT (AMY1)-Cagrilintide-Gs/β1/γ2; RAMP1
4.55	Single	9BUB	Cagrilintide	9BUB-CT-Cagrilintide-Gs/β1/γ2
4.55	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
4.55	Consensus	calcitonin_on_gp	Orthosteric Ligand	ctlike_on_gp
4.55	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
4.55	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
4.55	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
4.55	Consensus	crf2_on_gp	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
4.55	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
4.55	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
4.55	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
4.55	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
4.55	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
4.55	Consensus	pac1_on	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
4.55	Consensus	pac1_on_gp	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
4.55	Consensus	pac_on_gp	Orthosteric Ligand	pac1_on_gp
4.55	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
4.55	Consensus	vpac1_on_gp	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
4.55	Consensus	vpac_on_gp	Orthosteric Ligand	vpac1_on_gp vpac2_on_gp
4.35	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
4.35	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
4.35	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
4.35	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
4.35	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
4.35	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
4.35	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
4.35	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2
4.35	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
4.35	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
4.35	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
4.35	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
4.35	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.35	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
4.35	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
4.35	Single	8XFS	R-spondin-2	8XFS-LGR4-R-spondin-2-ZNRF3
4.35	Single	8ZH8	QRF-Amide	8ZH8-QRFP-QRF-Amide-Gq/β1/γ1
4.35	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
4.35	Single	9BUC	Cagrilintide	9BUC-CT-Cagrilintide-Gs/β1/γ2
4.35	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
4.35	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
4.35	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
4.35	Consensus	glp2_on_gp	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
4.35	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
4.35	Consensus	glp_on_gp	Orthosteric Ligand	glp1_on_gp glp2_on_gp
4.35	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
4.35	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.35	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.35	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
4.35	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
4.17	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/β1/γ2
4.17	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
4.17	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
4.17	Single	6NBH	Long-Acting PTH Analog	6NBH-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
4.17	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
4.17	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
4.17	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
4.17	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
4.17	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
4.17	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
4.17	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
4.17	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
4.17	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
4.17	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
4.17	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
4.17	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
4.17	Single	9BQ3	Cagrilintide	9BQ3-CT (AMY2)-Cagrilintide-Gs/β1/γ2; RAMP2
4.17	Single	9BTW	Cagrilintide	9BTW-CT (AMY3)-Cagrilintide-Gs/β1/γ2; RAMP3
4.17	Single	9BYO	Exendin-3	9BYO-GLP-1-Exendin-3-Gs/β1/γ2
4.17	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
4.17	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
4.17	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
4.17	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
4.17	Consensus	ctlike_on_gp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
4.17	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
4.17	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
4.17	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
4.17	Consensus	pth1_on	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
4.17	Consensus	vip-pacap_on	Orthosteric Ligand	vpac_on pac_on
4.17	Consensus	vip-pacap_on_gp	Orthosteric Ligand	vpac_on_gp pac_on_gp
4.17	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
4.17	Consensus	vpac2_on_gp	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
4.00	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
4.00	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
4.00	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
4.00	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-LSN3556672-chim(NtGi1-Gs)/β1/γ2
4.00	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
4.00	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/β1/γ2
4.00	Consensus	ccr5_on_gp	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
4.00	Consensus	class-a_class-b1_cons_on	Orthosteric Ligand	class-a_on class-b1_on
4.00	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.00	Consensus	gip_on	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
4.00	Consensus	gip_on_gp	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
4.00	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
4.00	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
3.85	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/β1/γ1
3.85	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
3.85	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
3.85	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
3.85	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
3.85	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
3.85	Single	8FLU	Long-Acting PTH	8FLU-PTH1-Long-Acting PTH-Gs/β1/γ2
3.85	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT (AMY1)-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
3.85	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
3.85	Consensus	glp1_on	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
3.85	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
3.85	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
3.70	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
3.70	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
3.70	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
3.70	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
3.70	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
3.70	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
3.70	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
3.70	Consensus	crf_on_gp	Orthosteric Ligand	crf2_on_gp crf1_on_gp
3.70	Consensus	glp1_on_gp	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
3.70	Consensus	pth1_on_gp	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
3.57	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
3.57	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
3.57	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
3.57	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/β1/γ2
3.57	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
3.57	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
3.57	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
3.57	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
3.57	Consensus	class-a_class-b1_cons_on_gp	Orthosteric Ligand	class-a_on_gp class-b1_on_gp
3.57	Consensus	glucagon_on	Orthosteric Ligand	glp_on gluc_on secretin_on gip_on
3.57	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
3.45	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
3.45	Consensus	gluc_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
3.45	Consensus	glucagon_on_gp	Orthosteric Ligand	glp_on_gp gluc_on_gp secretin_on_gp gip_on_gp
3.45	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
3.33	Consensus	gluc_on_gp	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
3.33	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
3.33	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
3.23	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
3.23	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on vip-pacap_on pth_on crf_on calcitonin_on
3.23	Consensus	pth2_on_gp	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
3.12	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
3.03	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
3.03	Consensus	pth_on_gp	Orthosteric Ligand	pth1_on_gp pth2_on_gp
2.86	Consensus	class-b1_on_gp	Orthosteric Ligand	glucagon_on_gp vip-pacap_on_gp pth_on_gp crf_on_gp calcitonin_on_gp
2.78	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:I796	R:R:Y792	13.3	5	No	Yes	8	9	2	2
R:R:Y792	S:S:L828	5.86	5	Yes	No	9	6	2	1
R:R:I796	S:S:L828	4.28	5	No	No	8	6	2	1
R:R:L799	X:X:?1	7.22	0	No	Yes	6	0	1	0
R:R:F801	R:R:I802	3.77	51	Yes	No	9	7	2	1
R:R:I802	X:X:?1	5.32	0	No	Yes	7	0	1	0
R:R:P803	X:X:?1	17.14	0	No	Yes	9	0	1	0
S:S:L590	S:S:P591	4.93	0	No	No	4	8	1	2
S:S:L590	X:X:?1	8.25	0	No	Yes	4	0	1	0
S:S:P591	S:S:V824	5.3	0	No	No	8	7	2	1
S:S:F801	S:S:W798	10.02	5	Yes	Yes	9	9	2	2
S:S:S825	S:S:W798	4.94	5	No	Yes	8	9	1	2
S:S:F801	S:S:S825	7.93	5	Yes	No	9	8	2	1
S:S:I804	S:S:T821	9.12	5	No	No	7	8	1	1
S:S:I804	X:X:?1	5.32	5	No	Yes	7	0	1	0
S:S:T821	X:X:?1	4.4	5	No	Yes	8	0	1	0
S:S:V824	X:X:?1	18.88	0	No	Yes	7	0	1	0
S:S:S825	X:X:?1	6.72	5	No	Yes	8	0	1	0
S:S:L828	X:X:?1	4.13	5	No	Yes	6	0	1	0
S:S:T820	X:X:?1	3.3	0	No	Yes	8	0	1	0
R:R:A800	S:S:I804	3.25	0	No	No	7	7	2	1
R:R:C795	R:R:L799	3.17	0	No	No	6	6	2	1
S:S:I817	S:S:T820	3.04	0	No	No	5	8	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
53.33	Single	8JD5	JNJ-40411813; ADX88178	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
27.78	Single	8XQT	Cholesterol	8XQT-TAS2R14-Cholesterol-Gi1/β1/γ1
18.18	Single	8XQL	Cholesterol	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
15.38	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
14.29	Single	8XQN	Cholesterol	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
14.29	Single	8XQS	Cholesterol	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
13.79	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
13.04	Single	8XQO	Cholesterol	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
12.50	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/β1/γ2
12.50	Single	9L3Z	LRH7-C2	9L3Z-CML1-LRH7-C2
12.00	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
11.76	Consensus	histamine_on	Orthosteric Ligand	h1_on h2_on h3_on h4_on
11.76	Consensus	histamine_on_gp	Orthosteric Ligand	h1_on_gp h2_on_gp h3_on_gp h4_on_gp
11.11	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/β1/γ2
11.11	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
11.11	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
11.11	Single	8Y01	Retinal	8Y01-Opsin1MW-Retinal-Gi1/β1/γ2
11.11	Single	8Y53	MK5046	8Y53-BB₃-MK5046-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
11.11	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
10.71	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
10.71	Consensus	calcitonin_on	Orthosteric Ligand	ctlike_on
10.53	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
10.53	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
10.53	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
10.53	Single	4U16	N-Methyl-Scopolamine	4U16-M₃-N-Methyl-Scopolamine
10.53	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
10.53	Single	5YC8	N-Methyl-Scopolamine	5YC8-M₂-N-Methyl-Scopolamine
10.53	Single	5ZK8	N-Methyl-Scopolamine	5ZK8-M₂-N-Methyl-Scopolamine
10.53	Single	5ZKC	N-Methyl-Scopolamine	5ZKC-M₂-N-Methyl-Scopolamine
10.53	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/β1/γ2
10.53	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
10.53	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
10.53	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
10.53	Single	8X9T	AP503	8X9T-ADGRD1-AP503-chim(NtGi1-Gs)/β1/γ2
10.53	Single	8YN8	Proxyfan	8YN8-H₃-Proxyfan-Go/β1/γ2
10.53	Single	9JEA	Atropine	9JEA-M₁-Atropine
10.53	Consensus	cck_off	Orthosteric Ligand	ccka_off
10.53	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
10.53	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
10.34	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
10.34	Consensus	calcitonin_on_gp	Orthosteric Ligand	ctlike_on_gp
10.34	Consensus	crf2_on_gp	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
10.00	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
10.00	Single	5ZK3	3-quinuclidinyl-benzilate	5ZK3-M₂-3-quinuclidinyl-benzilate
10.00	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/β1/γ1
10.00	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
10.00	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
10.00	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
10.00	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
10.00	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
10.00	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/β1/γ2
10.00	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2
10.00	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/β1/γ2
10.00	Single	8J18	(3R)-3-Hydroxydodecanoic acid	8J18-GPR84-(3R)-3-Hydroxydodecanoic acid-Gi1/β1/γ2
10.00	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/β1/γ2
10.00	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
10.00	Single	8XQP	Cholesterol	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
10.00	Consensus	adgrg2_on	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
10.00	Consensus	adgrg2_on_gp	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
10.00	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
10.00	Consensus	m2_off	Orthosteric Ligand	5ZKC-M₂-N-Methyl-Scopolamine 5ZK3-M₂-3-quinuclidinyl-benzilate 5ZKB-M₂-AF-DX 384
10.00	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
10.00	Consensus	m3_on_gp	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
9.76	Consensus	class-b1_on_gp	Orthosteric Ligand	glucagon_on_gp vip-pacap_on_gp pth_on_gp crf_on_gp calcitonin_on_gp
9.68	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/β1/γ2
9.68	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
9.68	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
9.68	Single	9BTW	Cagrilintide	9BTW-CT (AMY3)-Cagrilintide-Gs/β1/γ2; RAMP3
9.52	Single	2YDV	NECA	2YDV-A_2A-NECA
9.52	Single	3UON	3-quinuclidinyl-benzilate	3UON-M₂-3-quinuclidinyl-benzilate
9.52	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
9.52	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
9.52	Single	5G53	NECA	5G53-A_2A-NECA-Gs
9.52	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
9.52	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
9.52	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
9.52	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
9.52	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/β1/γ2
9.52	Single	7T9N	DPPC	7T9N-TSH-M22 Fab-DPPC-Gs/β1/γ2
9.52	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
9.52	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2
9.52	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
9.52	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
9.52	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
9.52	Single	9AS9	RS130-180	9AS9-5-HT_2A-RS130-180
9.52	Single	9ASA	RS130-180	9ASA-5-HT_2A-RS130-180-chim(NtGi1-Gs-CtGq)/β1/γ2
9.52	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-Methyl-Scopolamine 5ZHP-M₃-PubChem 134828589
9.52	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
9.52	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
9.52	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
9.52	Consensus	npy_off	Orthosteric Ligand	npy1_off npy2_off
9.38	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2
9.38	Consensus	crf1_on	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
9.09	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
9.09	Single	7EPE	NAM563	7EPE-mGlu2; mGlu2-NAM563
9.09	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
9.09	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2
9.09	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/β1/γ2
9.09	Single	8W8R	AA-14	8W8R-GPR101-AA-14-chim(NtGi1-Gs)/β1/γ2
9.09	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT (AMY1)-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
9.09	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_muscarinic gi_adrenergic gi_dopamine gi_histamine
9.09	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
8.82	Consensus	crf1_on_gp	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
8.82	Consensus	crf_on_gp	Orthosteric Ligand	crf2_on_gp crf1_on_gp
8.70	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/β1/γ2
8.70	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2
8.70	Single	8E9Y	Clozapine-N-oxide	8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
8.70	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
8.70	Single	8J19	LY237	8J19-GPR84-LY237-Gi1/β1/γ2
8.57	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
8.33	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
8.33	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
8.33	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
8.33	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
8.00	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
8.00	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
8.00	Single	8WDT	photoNECA	8WDT-A_2A-photoNECA
8.00	Single	9BUE	Cagrilintide	9BUE-CT-Cagrilintide-Gs/β1/γ2
7.89	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on vip-pacap_on pth_on crf_on calcitonin_on
7.69	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
7.69	Single	8WCB	Cyclohexylammonium Ion	8WCB-TA1-Cyclohexylammonium Ion-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Consensus	cckb_on	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
7.41	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
7.41	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
7.41	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
7.41	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
7.41	Single	9B54	A1AIW	9B54-CB₁-A1AIW-Gi1/β1/γ2
7.41	Consensus	cckb_on_gp	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
7.41	Consensus	nmur2_on	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
7.41	Consensus	nmur2_on_gp	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Single	7KH0	AVP	7KH0-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
7.14	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2
7.14	Single	7XKD	Beta-Hydroxyandrosterone	7XKD-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
7.14	Single	7XKE	Beta-Hydroxyandrosterone	7XKE-ADGRG2-β-Hydroxyandrosterone-chim(NtGi1-Gs)/β1/γ2
7.14	Single	8X9S	5alpha-DHT	8X9S-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
7.14	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
7.14	Single	9BLC	Cagrilintide backbone (non-acylated)	9BLC-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
7.14	Single	9EBO	GLP-1 (ACPC18)	9EBO-GLP-1-GLP-1 (ACPC18)-Gs/β1/γ2
7.14	Consensus	neuromedin-u_on	Orthosteric Ligand	nmur1_on nmur2_on
6.90	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
6.90	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
6.90	Consensus	neuromedin-u_on_gp	Orthosteric Ligand	nmur1_on_gp nmur2_on_gp
6.67	Single	6FJ3	PTH	6FJ3-PTH1-PTH
6.67	Single	6OY9	All-trans-Retinal	6OY9-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
6.67	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
6.67	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
6.67	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
6.67	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
6.67	Single	8Y02	Retinal	8Y02-OPN1SW-Retinal-Gi1/β1/γ2
6.67	Single	9BLW	Cagrilintide backbone (non-acylated)	9BLW-CT (AMY1)-Cagrilintide backbone (non-acylated)-Gs/β1/γ2; RAMP1
6.67	Single	9CHU	Noradrenaline	9CHU-β₂-Noradrenaline
6.67	Consensus	gs_histamine	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
6.67	Consensus	h2_on	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
6.67	Consensus	pac1_on	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
6.67	Consensus	pac1_on_gp	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
6.45	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
6.45	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
6.45	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
6.45	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
6.45	Single	8FEG	(DNCP)-Beta-Naloxamine	8FEG-κ-(DNCP)-β-Naloxamine-Gi1/β1/γ2
6.45	Single	9BUC	Cagrilintide	9BUC-CT-Cagrilintide-Gs/β1/γ2
6.25	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
6.25	Single	3UZA	GTPL9236	3UZA-A_2A-GTPL9236
6.25	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
6.25	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/β1/γ2
6.25	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
6.25	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
6.25	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
6.25	Single	8DPI	Lorcaserin	8DPI-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
6.25	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
6.25	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/β1/γ2
6.25	Single	8ITF	DMCHA	8ITF-TA9-DMCHA-chim(NtGi1-Gs)/β1/γ2
6.25	Single	8IW7	2-Phenylethylamine	8IW7-TA9-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
6.25	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/β1/γ2
6.25	Single	8POK	Histamine	8POK-H₂-Histamine-Gs/β1/γ2
6.25	Single	8RQL	Flufenamic acid	8RQL-TAS2R14-Flufenamic acid-Flufenamic acid-chim(NtGi1-Gt3)/β1/γ2
6.25	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
6.25	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
6.25	Single	8WC9	ZH8651	8WC9-TA1-ZH8651-chim(NtGi1-Gs-CtGq)/β1/γ2
6.25	Single	8X9U	Metenolone	8X9U-ADGRD1-Metenolone-chim(NtGi1-Gs)/β1/γ2
6.25	Single	8Y6W	4-CMTB	8Y6W-FFA2-TUG-1375-4-CMTB-Gi1/β1/γ2
6.25	Single	8YN9	Histamine	8YN9-H₄-Histamine-Gi1/β1/γ2
6.25	Single	8YUU	Histamine	8YUU-H₃-Histamine-Gi1/β1/γ1
6.25	Single	9BQ3	Cagrilintide	9BQ3-CT (AMY2)-Cagrilintide-Gs/β1/γ2; RAMP2
6.25	Single	9LRC	Histamine	9LRC-H₄-Histamine
6.25	Single	9LRE	Histamine	9LRE-H₄-Histamine-Gi1/β1/γ2
6.25	Consensus	h2_on_gp	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
6.25	Consensus	h3_on	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
6.25	Consensus	h3_on_gp	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
6.25	Consensus	pth1_on	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
6.25	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
6.25	Consensus	vpac2_on_gp	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
6.06	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-LSN3556672-chim(NtGi1-Gs)/β1/γ2
6.06	Single	8ZJE	TAK-448	8ZJE-Kiss1-TAK-448-chim(NtGi1-Gq)/β1/γ1
5.88	Single	1U19	11-cis-Retinal	1U19-Rhodopsin-11-cis-Retinal
5.88	Single	2G87	All-trans-Retinal	2G87-Rhodopsin-All-trans-Retinal
5.88	Single	2I35	11-cis-Retinal	2I35-Rhodopsin-11-cis-Retinal
5.88	Single	3AYM	All-trans-Retinal	3AYM-Rhodopsin-All-trans-Retinal
5.88	Single	3PBL	Eticlopride	3PBL-D₃-Eticlopride
5.88	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
5.88	Single	6TP4	ACT-462206	6TP4-OX₁-ACT-462206
5.88	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
5.88	Single	7DFL	Histamine	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
5.88	Single	7E2Y	Serotonin	7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2
5.88	Single	7LD3	MIPS521	7LD3-A₁-Adenosine-MIPS521-Gi2/β1/γ2
5.88	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
5.88	Single	7UL2	SR48692	7UL2-NTS₁-SR48692-Na
5.88	Single	7XKF	Beta-Hydroxyandrosterone	7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
5.88	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/β1/γ2
5.88	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
5.88	Single	7XTB	Serotonin	7XTB-5-HT₆-Serotonin-Gs/β1/γ2
5.88	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	7YS6	Serotonin	7YS6-5-HT₆-Serotonin-chim(NtGi1-Gs)/β1/γ2
5.88	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
5.88	Single	8DPF	Lorcaserin	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.88	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/β1/γ2
5.88	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
5.88	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
5.88	Single	8GGY	Constrained Epinephrine	8GGY-β₂-Constrained Epinephrine
5.88	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/β1/γ2
5.88	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/β1/γ2
5.88	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2
5.88	Single	8YKD	Dehydroepiandrosterone	8YKD-ADGRG2-Dehydroepiandrosterone-chim(NtGi1-Gs)/β1/γ2
5.88	Single	8YN2	Histamine	8YN2-H₁-Histamine-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.88	Single	8YN4	Histamine	8YN4-H₂-Histamine-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.88	Single	8YN5	Histamine	8YN5-H₃-Histamine-Gi1/β1/γ2
5.88	Single	8YN6	Imetit	8YN6-H₃-Imetit-Gi1/β1/γ2
5.88	Single	8YN7	Immethridine	8YN7-H₃-Immethridine-Go/β1/γ2
5.88	Single	8ZSV	RO5263397	8ZSV-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
5.88	Single	9AS2	DMT	9AS2-5-HT_2A-DMT-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	9AS7	Psilocin	9AS7-5-HT_2A-Psilocin
5.88	Single	9EPR	Retinal	9EPR-Rhodopsin-Retinal-Gi1/β1/γ2
5.88	Single	9IJE	Epinephrine	9IJE-β₃-Epinephrine-chim(NtGi1-Gs)/β1/γ2
5.88	Single	9IXJ	Histamine	9IXJ-H₂-Histamine-Gs/β1/γ2
5.88	Consensus	5ht4_on	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
5.88	Consensus	5ht4_on_gp	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
5.88	Consensus	adgrg_on	Orthosteric Ligand	adgrg2_on adgrg4_on
5.88	Consensus	adgrg_on_gp	Orthosteric Ligand	adgrg2_on_gp adgrg4_on_gp
5.88	Consensus	d3_off	Orthosteric Ligand	3PBL-D₃-Eticlopride
5.88	Consensus	h1_on	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
5.88	Consensus	h4_on	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
5.88	Consensus	neurotensin_off	Orthosteric Ligand	nts1_off
5.88	Consensus	nts1_off	Orthosteric Ligand	7UL2-NTS₁-SR48692-Na
5.71	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
5.71	Consensus	pth1_on_gp	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
5.56	Single	2PED	9-cis-Retinal	2PED-Rhodopsin-9-cis-Retinal
5.56	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
5.56	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
5.56	Single	3VG9	ZM-241385	3VG9-A_2A-ZM-241385-Antibody
5.56	Single	3VGA	ZM-241385	3VGA-A_2A-ZM-241385-Antibody
5.56	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
5.56	Single	5K2D	ZM-241385	5K2D-A_2A-ZM-241385-Na
5.56	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
5.56	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
5.56	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
5.56	Single	5U09	Taranabant	5U09-CB₁-Taranabant
5.56	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/β1/γ2
5.56	Single	6JZH	ZM-241385	6JZH-A_2A-ZM-241385-Na
5.56	Single	6KUY	PubChem 145704643	6KUY-α_2a-PubChem 145704643
5.56	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
5.56	Single	6NWE	Octyl-Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
5.56	Single	6OBA	S-Alprenolol	6OBA-β₂-S-Alprenolol-GTPL11074
5.56	Single	6PS7	ZM-241385	6PS7-A_2A-ZM-241385-Na
5.56	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
5.56	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
5.56	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
5.56	Single	7DHR	Isoprenaline	7DHR-β₂-Isoprenaline-Gs/β1/γ2
5.56	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/β1/γ2
5.56	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
5.56	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
5.56	Single	7LJD	Dopamine	7LJD-D₁-Dopamine-Mevidalen-Gs/β1/γ1
5.56	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
5.56	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
5.56	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
5.56	Single	7SRS	LSD	7SRS-5-HT_2B-LSD-Arrestin2
5.56	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2
5.56	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
5.56	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
5.56	Single	7T96	Acetylcholine	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
5.56	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
5.56	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/β1/γ2
5.56	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/β1/γ2
5.56	Single	7X2F	Dopamine	7X2F-D₁-Dopamine-Mevidalen-Gs/β1/γ2
5.56	Single	7X5H	5-CT	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2
5.56	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/β1/γ2
5.56	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/β1/γ2
5.56	Single	7YM8	Oxymetazoline	7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)
5.56	Single	7YMH	Norepinephrine	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)
5.56	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
5.56	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
5.56	Single	8FYX	Buspirone	8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1
5.56	Single	8GGA	Constrained Epinephrine	8GGA-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8GGR	Constrained Epinephrine	8GGR-β₂-Constrained Epinephrine
5.56	Single	8GH0	Constrained Epinephrine	8GH0-β₂-Constrained Epinephrine
5.56	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/β1/γ2
5.56	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/β1/γ2
5.56	Single	8IW4	Spermidine	8IW4-TA9-Spermidine-chim(NtGi1-Gs)/β1/γ2
5.56	Single	8IWE	Spermidine	8IWE-TA9-Spermidine
5.56	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2
5.56	Single	8TZQ	L-Dopamine	8TZQ-D₂-L-Dopamine-Go/β1/γ2
5.56	Single	8UNS	Constrained Epinephrine	8UNS-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8UNT	Constrained Epinephrine	8UNT-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8UNX	Constrained Epinephrine	8UNX-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8WC3	SEP-363856	8WC3-TA1-SEP-363856-chim(NtGi1-Gs)/β1/γ2
5.56	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
5.56	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
5.56	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
5.56	Single	8Y0H	VUF11418	8Y0H-CXCR3-VUF11418
5.56	Single	8Y0N	VUF11418	8Y0N-CXCR3-VUF11418-Go/β1/γ2
5.56	Single	8YNA	Immepip	8YNA-H₄-Immepip-Gi1/β1/γ2
5.56	Single	8YUT	Amthamine	8YUT-H₂-Amthamine-Gs/β1/γ2
5.56	Single	8YUV	Immepip	8YUV-H₃-Immepip-Gi1/β1/γ2
5.56	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
5.56	Single	9CLW	4-CMTB	9CLW-FFA2-TUG-1375-4-CMTB-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.56	Single	9EBH	Adenosine	9EBH-A_3A-Adenosine-Gi1/β1/γ2
5.56	Single	9EEA	Adenosine	9EEA-A_2A-Adenosine-Gs/β1/γ2
5.56	Single	9H2X	A1IR1	9H2X-A_2A-A1IR1-Na
5.56	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.56	Single	9KPE	SA0	9KPE-TAS2R16-SA0-Gi1/β1/γ2
5.56	Single	9LRB	Histamine	9LRB-H₁-Histamine-Gs/β1/γ2
5.56	Single	9MQJ	Isoquinuclidine	9MQJ-μ-Isoquinuclidine
5.56	Consensus	5ht1e_on	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
5.56	Consensus	5ht_on	Orthosteric Ligand	5ht1_on 5ht2_on 5ht4_on 5ht5_on 5ht6_on 5ht7_on
5.56	Consensus	alpha2_off	Orthosteric Ligand	alpha2c_off
5.56	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
5.56	Consensus	gq_histamine	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
5.56	Consensus	gs_5ht	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2 7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2 7XT8-5-HT₄-Serotonin-Gs/β1/γ2
5.56	Consensus	h1_on_gp	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
5.56	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
5.56	Consensus	m2_on_gp	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
5.56	Consensus	rhodopsin_off	Orthosteric Ligand	1U19-Rhodopsin-11-cis-Retinal 2PED-Rhodopsin-9-cis-Retinal 5TE5-Rhodopsin-20-Methanoretinal
5.26	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
5.26	Single	3REY	XAC	3REY-A_2A-XAC
5.26	Single	3RZE	Cidoxepin	3RZE-H₁-Cidoxepin
5.26	Single	3UZC	4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol	3UZC-A_2A-4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol
5.26	Single	4LDO	L-Epinephrine	4LDO-β₂-L-Epinephrine
5.26	Single	4MQT	Iperoxo	4MQT-M₂-Iperoxo-LY2119620
5.26	Single	5IU4	ZM-241385	5IU4-A_2A-ZM-241385-Na
5.26	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
5.26	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
5.26	Single	5JTB	ZM-241385	5JTB-A_2A-ZM-241385
5.26	Single	5K2B	ZM-241385	5K2B-A_2A-ZM-241385-Na
5.26	Single	5K2C	ZM-241385	5K2C-A_2A-ZM-241385-Na
5.26	Single	5NLX	ZM-241385	5NLX-A_2A-ZM-241385-Na
5.26	Single	5NM4	ZM-241385	5NM4-A_2A-ZM-241385-Na
5.26	Single	5TE3	Octyl-Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl-β-D-Glucopyranoside
5.26	Single	5UVI	ZM-241385	5UVI-A_2A-ZM-241385
5.26	Single	6A94	Zotepine	6A94-5-HT_2A-Zotepine
5.26	Single	6AQF	ZM-241385	6AQF-A_2A-ZM-241385
5.26	Single	6FFI	MMPEP	6FFI-mGlu₅-MMPEP
5.26	Single	6IQL	L745870	6IQL-D₄-L745870
5.26	Single	6K41	Dexmedetomidine	6K41-α_2b-Dexmedetomidine-Go/β1/γ2
5.26	Single	6KUX	RS-79948	6KUX-α_2a-RS-79948
5.26	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
5.26	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
5.26	Single	6PS0	S-Carazolol	6PS0-β₂-S-Carazolol
5.26	Single	6PS4	ICI118-551	6PS4-β₂-ICI118-551
5.26	Single	6PS5	S-Propranolol	6PS5-β₂-S-Propranolol
5.26	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
5.26	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
5.26	Single	6TPG	EMPA	6TPG-OX₂-EMPA
5.26	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
5.26	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
5.26	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
5.26	Single	6ZDV	Chromone 5d	6ZDV-A_2A-Chromone 5d-Na
5.26	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
5.26	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/β1/γ2
5.26	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/β1/γ2
5.26	Single	7CMU	Pramipexole	7CMU-D₃-Pramipexole-Gi1/β1/γ2
5.26	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/β1/γ2
5.26	Single	7DHI	Salbutamol	7DHI-β₂-Salbutamol-Gs/β1/γ2
5.26	Single	7E33	BRL-54443	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2
5.26	Single	7EJ8	Brimonidine	7EJ8-α_2a-Brimonidine-Go/β1/γ2
5.26	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/β1/γ2
5.26	Single	7F24	Dopamine	7F24-D₁-Dopamine-GDP-Gs/β1/γ2
5.26	Single	7RAN	PubChem 164575847	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	7T32	ZM-241385	7T32-A_2A-ZM-241385
5.26	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-LY2119620-chim(NtGi1-Go)/β1/γ2
5.26	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/β1/γ2
5.26	Single	7UM7	Methylergometrine	7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
5.26	Single	7UTZ	DPPC	7UTZ-TSH-TR1402-DPPC-Gs/β1/γ2
5.26	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
5.26	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
5.26	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/β1/γ2
5.26	Single	8FCZ	11-cis-Retinal	8FCZ-Rhodopsin-11-cis-Retinal
5.26	Single	8GE1	Constrained Epinephrine	8GE1-β₂-Constrained Epinephrine-Gs/β1/γ2
5.26	Single	8GE4	Constrained Epinephrine	8GE4-β₂-Constrained Epinephrine-Gs/β1/γ2
5.26	Single	8GE6	Constrained Epinephrine	8GE6-β₂-Constrained Epinephrine-Gs/β1/γ2
5.26	Single	8GE7	Constrained Epinephrine	8GE7-β₂-Constrained Epinephrine-Gs/β1/γ2
5.26	Single	8GE8	Constrained Epinephrine	8GE8-β₂-Constrained Epinephrine-Gs/β1/γ2
5.26	Single	8GEA	Constrained Epinephrine	8GEA-β₂-Constrained Epinephrine-Gs/β1/γ2
5.26	Single	8GED	Constrained Epinephrine	8GED-β₂-Constrained Epinephrine-Gs/β1/γ2
5.26	Single	8GEF	Constrained Epinephrine	8GEF-β₂-Constrained Epinephrine-Gs/β1/γ2
5.26	Single	8GG5	Constrained Epinephrine	8GG5-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8GG7	Constrained Epinephrine	8GG7-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8GG8	Constrained Epinephrine	8GG8-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8GGL	Constrained Epinephrine	8GGL-β₂-Constrained Epinephrine
5.26	Single	8GGM	Constrained Epinephrine	8GGM-β₂-Constrained Epinephrine
5.26	Single	8GGP	Constrained Epinephrine	8GGP-β₂-Constrained Epinephrine
5.26	Single	8GGQ	Constrained Epinephrine	8GGQ-β₂-Constrained Epinephrine
5.26	Single	8GGS	Constrained Epinephrine	8GGS-β₂-Constrained Epinephrine
5.26	Single	8GGT	Constrained Epinephrine	8GGT-β₂-Constrained Epinephrine
5.26	Single	8GGV	Constrained Epinephrine	8GGV-β₂-Constrained Epinephrine
5.26	Single	8GGX	Constrained Epinephrine	8GGX-β₂-Constrained Epinephrine
5.26	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/β1/γ2
5.26	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/β1/γ2
5.26	Single	8JLN	T1AM	8JLN-TA1-T1AM-Gs/β1/γ2
5.26	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/β1/γ2
5.26	Single	8JSP	Ulotaront	8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2
5.26	Single	8PM2	DMCH	8PM2-TA7-DMCH-Gs/β1/γ2
5.26	Single	8RQQ	ZM-241385	8RQQ-A_2A-ZM-241385-Na
5.26	Single	8THK	A61603	8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	8THL	Epinephrine	8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	8U02	L-Dopamine	8U02-D₂-L-Dopamine-Go/β1/γ2
5.26	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/β1/γ2
5.26	Single	8UNL	Constrained Epinephrine	8UNL-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8UNM	Constrained Epinephrine	8UNM-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8UNO	Constrained Epinephrine	8UNO-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8UNW	Constrained Epinephrine	8UNW-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8UO1	Constrained Epinephrine	8UO1-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
5.26	Single	8V6U	PubChem 171392456	8V6U-5-HT_2A-PubChem 171392456-chim(NtGi2-Gs-CtGq)/β1/γ2
5.26	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/β1/γ2
5.26	Single	8W8B	SEP-363856	8W8B-5-HT_1A-SEP-363856-Gi1/β1/γ2
5.26	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
5.26	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
5.26	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	8YN3	Histamine	8YN3-H₂-Histamine-Gs/β1/γ2
5.26	Single	8ZMG	Pimavanserin	8ZMG-5-HT_2A-Pimavanserin
5.26	Single	9ARX	Serotonin	9ARX-5-HT_2A-Serotonin
5.26	Single	9AS3	LSD	9AS3-5-HT_2A-LSD
5.26	Single	9AS4	LSD	9AS4-5-HT_2A-LSD-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	9AS5	Mescaline	9AS5-5-HT_2A-Mescaline
5.26	Single	9AS6	Mescaline	9AS6-5-HT_2A-Mescaline-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
5.26	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	9BA0	A1AKN	9BA0-CB₁-A1AKN
5.26	Single	9CBL	Epinephrine	9CBL-α_2a-Epinephrine-Gi1/β1/γ2
5.26	Single	9DQJ	EP-3945	9DQJ-MRGPRD-EP-3945-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	9EPQ	11,20-Ethanoretinal	9EPQ-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
5.26	Single	9JKQ	METH	9JKQ-TA1-METH-Gs/β1/γ2
5.26	Single	9MQI	Isoquinuclidine	9MQI-μ-Isoquinuclidine
5.26	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6A93-5-HT_2A-Risperidone 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 8JT8-5-HT_2A-(R)-IHCH-7179
5.26	Consensus	5ht_on_gp	Orthosteric Ligand	5ht1_on_gp 5ht2_on_gp 5ht4_on_gp 5ht5_on_gp 5ht6_on_gp 5ht7_on_gp
5.26	Consensus	a2_off	Orthosteric Ligand	a2a_off
5.26	Consensus	a2a_off	Orthosteric Ligand	3RFM-A_2A-Caffeine 8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-2-118 8PWN-A_2A-Theophylline 5IU4-A_2A-ZM-241385-Na 5OLZ-A_2A-PubChem 135566609-Na 6GT3-A_2A-Imaradenant-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PSB-36-Na 5IU7-A_2A-Q27456346-Na 5OLH-A_2A-Vipadenant-Na 5OLO-A_2A-Tozadenant-Na 6ZDR-A_2A-HMS1413f12-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5IU8-A_2A-Q27456347-Na 5IUB-A_2A-Q27456344-Na 6ZDV-A_2A-Chromone 5d-Na 5IUA-A_2A-Q27456348-Na 8A2P-A_2A-LUAA47070-Na
5.26	Consensus	alpha1_on	Orthosteric Ligand	alpha1a_on
5.26	Consensus	alpha1_on_gp	Orthosteric Ligand	alpha1a_on_gp
5.26	Consensus	alpha1a_on	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2
5.26	Consensus	alpha1a_on_gp	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2
5.26	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
5.26	Consensus	d3_on	Orthosteric Ligand	7CMV-D₃-PD128907-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2
5.26	Consensus	d3_on_gp	Orthosteric Ligand	7CMV-D₃-PD128907-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2
5.26	Consensus	gluc_on_gp	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
5.26	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
5.26	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-C-35 5DHH-NOP-SB-612111
5.26	Consensus	opsins_off	Orthosteric Ligand	rhodopsin_off
5.26	Consensus	sensory_off	Orthosteric Ligand	opsins_off
5.00	Single	1HZX	11-cis-Retinal	1HZX-Rhodopsin-11-cis-Retinal
5.00	Single	2VT4	Cyanopindolol	2VT4-β₁-Cyanopindolol
5.00	Single	2Y01	Dobutamine	2Y01-β₁-Dobutamine
5.00	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
5.00	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
5.00	Single	2YCY	Cyanopindolol	2YCY-β₁-Cyanopindolol
5.00	Single	3EML	ZM-241385	3EML-A_2A-ZM-241385
5.00	Single	3NY8	ICI118-551	3NY8-β₂-ICI118-551
5.00	Single	3NYA	S-Alprenolol	3NYA-β₂-S-Alprenolol
5.00	Single	3ZPQ	4-(piperazin-1- yl)-1H-indole	3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na
5.00	Single	3ZPR	4-methyl-2-(piperazin-1-yl)	3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
5.00	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
5.00	Single	4EIY	ZM-241385	4EIY-A_2A-ZM-241385-Na
5.00	Single	4GBR	S-Carazolol	4GBR-β₂-S-Carazolol
5.00	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl β-D-Glucopyranoside-Gt(CT)
5.00	Single	5DHG	C-35	5DHG-NOP-C-35
5.00	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
5.00	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
5.00	Single	5K2A	ZM-241385	5K2A-A_2A-ZM-241385-Na
5.00	Single	5OLG	ZM-241385	5OLG-A_2A-ZM-241385-Na
5.00	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
5.00	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
5.00	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
5.00	Single	5UEN	DU172	5UEN-A₁-DU172
5.00	Single	5UIG	Cmpd-1	5UIG-A_2A-Cmpd-1
5.00	Single	5VRA	ZM-241385	5VRA-A_2A-ZM-241385-Na
5.00	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
5.00	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
5.00	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
5.00	Single	6GPS	MK0812	6GPS-CCR2-MK0812
5.00	Single	6H7M	Salbutamol	6H7M-β₁-Salbutamol
5.00	Single	6K42	Dexmedetomidine	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
5.00	Single	6LPJ	ZM-241385	6LPJ-A_2A-ZM-241385-Na
5.00	Single	6LPK	ZM-241385	6LPK-A_2A-ZM-241385-Na
5.00	Single	6PRZ	S-Alprenolol	6PRZ-β₂-S-Alprenolol
5.00	Single	6PS1	Timolol	6PS1-β₂-Timolol
5.00	Single	6PS2	S-Alprenolol	6PS2-β₂-S-Alprenolol
5.00	Single	6S0L	ZM-241385	6S0L-A_2A-ZM-241385
5.00	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
5.00	Single	7BTS	L-Epinephrine	7BTS-β₁-L-Epinephrine
5.00	Single	7BU6	L-Norepinephrine	7BU6-β₁-L-Norepinephrine
5.00	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/β1/γ2
5.00	Single	7E32	Serotonin	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
5.00	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
5.00	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/β1/γ2
5.00	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/β1/γ2
5.00	Single	7LJC	SKF-81297	7LJC-D₁-SKF-81297-Mevidalen-Gs/β1/γ2
5.00	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
5.00	Single	7RBT	LSN3556672	7RBT-GIP-Tirzepatide-LSN3556672-chim(NtGi1-Gs)/β1/γ2
5.00	Single	7S0G	Isoprenaline	7S0G-β₁-Isoprenaline-chim(Gi1-CtGs)/β1/γ2
5.00	Single	7T2G	Mitragynine Pseudoindoxyl	7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2
5.00	Single	7UM5	5-CT	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/β1/γ2
5.00	Single	7UM6	Lisuride	7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2
5.00	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/β1/γ2
5.00	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/β1/γ1
5.00	Single	7WC7	Lisuride	7WC7-5-HT_2A-Lisuride
5.00	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
5.00	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
5.00	Single	7XJH	Isoproterenol	7XJH-β₃-Isoproterenol-Gs/β1/γ2
5.00	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/β1/γ2
5.00	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
5.00	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
5.00	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
5.00	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2
5.00	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/β1/γ2
5.00	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
5.00	Single	8FY8	5-MeO-DMT	8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1
5.00	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/β1/γ2
5.00	Single	8GE3	Constrained Epinephrine	8GE3-β₂-Constrained Epinephrine-Gs/β1/γ2
5.00	Single	8GE9	Constrained Epinephrine	8GE9-β₂-Constrained Epinephrine-Gs/β1/γ2
5.00	Single	8GEC	Constrained Epinephrine	8GEC-β₂-Constrained Epinephrine-Gs/β1/γ2
5.00	Single	8GEE	Constrained Epinephrine	8GEE-β₂-Constrained Epinephrine-Gs/β1/γ2
5.00	Single	8GEH	Constrained Epinephrine	8GEH-β₂-Constrained Epinephrine-Gs/β1/γ2
5.00	Single	8GFV	Constrained Epinephrine	8GFV-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8GFW	Constrained Epinephrine	8GFW-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8GFX	Constrained Epinephrine	8GFX-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8GFZ	Constrained Epinephrine	8GFZ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8GG0	Constrained Epinephrine	8GG0-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8GG1	Constrained Epinephrine	8GG1-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8GG3	Constrained Epinephrine	8GG3-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8GG4	Constrained Epinephrine	8GG4-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8GG6	Constrained Epinephrine	8GG6-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8GG9	Constrained Epinephrine	8GG9-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8GGI	Constrained Epinephrine	8GGI-β₂-Constrained Epinephrine
5.00	Single	8GGJ	Constrained Epinephrine	8GGJ-β₂-Constrained Epinephrine
5.00	Single	8GGK	Constrained Epinephrine	8GGK-β₂-Constrained Epinephrine
5.00	Single	8GGN	Constrained Epinephrine	8GGN-β₂-Constrained Epinephrine
5.00	Single	8GGO	Constrained Epinephrine	8GGO-β₂-Constrained Epinephrine
5.00	Single	8GGU	Constrained Epinephrine	8GGU-β₂-Constrained Epinephrine
5.00	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/β1/γ2
5.00	Single	8JD0	NAM563	8JD0-mGlu2; mGlu3-Glutamate-NAM563
5.00	Single	8JJO	Alprenolol	8JJO-β₂-Alprenolol
5.00	Single	8JLJ	T1AM	8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2
5.00	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/β1/γ2
5.00	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
5.00	Single	8JXR	LSD	8JXR-D₁-LSD
5.00	Single	8PJK	ST171	8PJK-5-HT_1A-ST171-Gi1/β1/γ1
5.00	Single	8T1W	CVN424	8T1W-GPR6-CVN424
5.00	Single	8UGY	Mianserin	8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1
5.00	Single	8UH3	Setiptiline	8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
5.00	Single	8UNQ	Constrained Epinephrine	8UNQ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8UNR	Constrained Epinephrine	8UNR-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8UNU	Constrained Epinephrine	8UNU-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8UNV	Constrained Epinephrine	8UNV-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8UNY	Constrained Epinephrine	8UNY-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8UNZ	Constrained Epinephrine	8UNZ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8UO2	Constrained Epinephrine	8UO2-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.00	Single	8UWL	Lisuride	8UWL-5-HT_2A-Lisuride-chim(NtGi2-Gs-CtGq)/β1/γ2
5.00	Single	8VVG	GB18	8VVG-κ-GB18-Gi1/β1/γ2
5.00	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2
5.00	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
5.00	Single	8WC7	ZH8667	8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2
5.00	Single	8X63	Mepyramine	8X63-H₁-Mepyramine
5.00	Single	8X64	Desloratadine	8X64-H₁-Desloratadine
5.00	Single	8XVK	Ambrisentan	8XVK-ET_A-Ambrisentan
5.00	Single	8ZQE	GPR15L(C11)	8ZQE-GPR15-GPR15L(C11)-Gi1/β1/γ1
5.00	Single	8ZSS	RO5263397	8ZSS-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
5.00	Single	9AS1	DMT	9AS1-5-HT_2A-DMT
5.00	Single	9BQJ	RO76	9BQJ-μ-RO76-Gi1/β1/γ2
5.00	Single	9CBM	Dexmedetomidine	9CBM-α_2a-Dexmedetomidine-Gi1/β1/γ2
5.00	Single	9CHX	S-Carazolol	9CHX-β₂-S-Carazolol
5.00	Single	9D61	JDTic	9D61-κ-JDTic-Gi1/β1/γ2
5.00	Single	9H37	A1IR0	9H37-A_2A-A1IR0-Na
5.00	Single	9PLN	N-(5-methylnaphthalen-1-yl)pyridin-4-amine	9PLN-α_2a-N-(5-methylnaphthalen-1-yl)pyridin-4-amine
5.00	Single	9PLO	N-(5-methylnaphthalen-1-yl)pyridin-4-amine	9PLO-α_2a-N-(5-methylnaphthalen-1-yl)pyridin-4-amine-Go/β1/γ2
5.00	Single	9PQD	(6m)-1-methyl-6-(1,2,5,6-tetrahydropyridin-3-yl)-1h-indole	9PQD-α_2a-(6m)-1-methyl-6-(1,2,5,6-tetrahydropyridin-3-yl)-1h-indole
5.00	Consensus	5ht1d_on	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
5.00	Consensus	5ht1d_on_gp	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
5.00	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide
5.00	Consensus	5ht5_on	Orthosteric Ligand	5ht5a_on
5.00	Consensus	5ht5a_on	Orthosteric Ligand	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
5.00	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
5.00	Consensus	5ht6_on_gp	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
5.00	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2
5.00	Consensus	5ht7_on_gp	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2
5.00	Consensus	adrenergic_on	Orthosteric Ligand	alpha_on beta_on
5.00	Consensus	alpha2_on	Orthosteric Ligand	alpha2b_on
5.00	Consensus	alpha2_on_gp	Orthosteric Ligand	alpha2b_on_gp
5.00	Consensus	alpha2b_on	Orthosteric Ligand	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
5.00	Consensus	alpha2b_on_gp	Orthosteric Ligand	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
5.00	Consensus	alpha_on	Orthosteric Ligand	alpha1_on alpha2_on
5.00	Consensus	ccr2_off	Orthosteric Ligand	6GPS-CCR2-MK0812
5.00	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
5.00	Consensus	dopamine_off	Orthosteric Ligand	d2_off d3_off
5.00	Consensus	dopamine_on	Orthosteric Ligand	d2_on d1_on d3_on d4_on d5_on
5.00	Consensus	dopamine_on_gp	Orthosteric Ligand	d2_on_gp d1_on_gp d3_on_gp d4_on_gp d5_on_gp
5.00	Consensus	gi_histamine	Orthosteric Ligand	8JXX-H₄-Clobenpropit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8YUU-H₃-Histamine-Gi1/β1/γ1 8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2
5.00	Consensus	gq_amine	Orthosteric Ligand	gq_muscarinic gq_histamine
5.00	Consensus	gs_trace-amine	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/β1/γ2 8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2 8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
5.00	Consensus	histamine_off	Orthosteric Ligand	h1_off
5.00	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
5.00	Consensus	muscarinic_on_gp	Orthosteric Ligand	m2_on_gp m3_on_gp m4_on_gp m1_on_gp
4.88	Consensus	pth_on_gp	Orthosteric Ligand	pth1_on_gp pth2_on_gp
4.76	Single	2RH1	S-Carazolol	2RH1-β₂-S-Carazolol
4.76	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
4.76	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
4.76	Single	2YCW	S-Carazolol	2YCW-β₁-S-Carazolol
4.76	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
4.76	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
4.76	Single	4WW3	All-trans-Retinal	4WW3-Rhodopsin-All-trans-Retinal
4.76	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
4.76	Single	5C1M	BU72	5C1M-μ-BU72
4.76	Single	5D6L	S-Carazolol	5D6L-β₂-S-Carazolol
4.76	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
4.76	Single	5JQH	S-Carazolol	5JQH-β₂-S-Carazolol
4.76	Single	5NM2	ZM-241385	5NM2-A_2A-ZM-241385-Na
4.76	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
4.76	Single	5T1A	BMS-681	5T1A-CCR2-BMS-681-PubChem 12093170
4.76	Single	5TVN	LSD	5TVN-5-HT_2B-LSD
4.76	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
4.76	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
4.76	Single	5WQC	EMPA	5WQC-OX₂-EMPA
4.76	Single	5X7D	S-Carazolol	5X7D-β₂-S-Carazolol-Cmpd-15
4.76	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
4.76	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
4.76	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
4.76	Single	6E67	BI167107	6E67-β₂-BI167107-Gs(CT)
4.76	Single	6GPX	MK0812	6GPX-CCR2-MK0812
4.76	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
4.76	Single	6KUW	PubChem 57213234	6KUW-α_2c-PubChem 57213234
4.76	Single	6LPL	ZM-241385	6LPL-A_2A-ZM-241385-Na
4.76	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
4.76	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
4.76	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
4.76	Single	6PS3	S-Carvedilol	6PS3-β₂-S-Carvedilol
4.76	Single	6PS6	Timolol	6PS6-β₂-Timolol
4.76	Single	6S0Q	ZM-241385	6S0Q-A_2A-ZM-241385
4.76	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
4.76	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
4.76	Single	6WQA	ZM-241385	6WQA-A_2A-ZM-241385-Na
4.76	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
4.76	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
4.76	Single	7BVQ	S-Carazolol	7BVQ-β₁-S-Carazolol
4.76	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
4.76	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/β1/γ2
4.76	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
4.76	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
4.76	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-MIPS521-Gi2/β1/γ2
4.76	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
4.76	Single	7RM5	ZM-241385	7RM5-A_2A-ZM-241385-Na
4.76	Single	7S0F	Isoprenaline	7S0F-β₁-Isoprenaline-Gi1/β1/γ2
4.76	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/β1/γ2
4.76	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
4.76	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/β1/γ2
4.76	Single	7W41	PD176252	7W41-BB₂-PD176252
4.76	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
4.76	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/β1/γ2
4.76	Single	7XK9	Constrained Isoproterenol	7XK9-β₂-Constrained Isoproterenol-Na
4.76	Single	7XKA	Constrained Epinephrine	7XKA-β₂-Constrained Epinephrine
4.76	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
4.76	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/β1/γ2
4.76	Single	8FYN	ZM-241385	8FYN-A_2A-ZM-241385-Na
4.76	Single	8GDZ	Constrained Epinephrine	8GDZ-β₂-Constrained Epinephrine-Gs/β1/γ2
4.76	Single	8GEB	Constrained Epinephrine	8GEB-β₂-Constrained Epinephrine-Gs/β1/γ2
4.76	Single	8GEG	Constrained Epinephrine	8GEG-β₂-Constrained Epinephrine-Gs/β1/γ2
4.76	Single	8GFY	Constrained Epinephrine	8GFY-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
4.76	Single	8GG2	Constrained Epinephrine	8GG2-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
4.76	Single	8GGB	Constrained Epinephrine	8GGB-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
4.76	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
4.76	Single	8JXS	PF-6142	8JXS-D₁-PF-6142
4.76	Single	8QOT	Nanobody-E	8QOT-μ-Nanobody-E
4.76	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
4.76	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
4.76	Single	8UNN	Constrained Epinephrine	8UNN-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
4.76	Single	8UNP	Constrained Epinephrine	8UNP-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
4.76	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
4.76	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
4.76	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
4.76	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
4.76	Single	8YNS	SNAP-94847	8YNS-MCH1-SNAP-94847
4.76	Single	8ZMF	A1L10	8ZMF-5-HT_2C-A1L10
4.76	Single	8ZVZ	BW245C	8ZVZ-DP₁-BW245C-Gs/β1/γ2
4.76	Single	8ZYT	Neurotensin peptide 8-13	8ZYT-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
4.76	Single	9ARY	Serotonin	9ARY-5-HT_2A-Serotonin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	9ARZ	2-bromo-LSD	9ARZ-5-HT_2A-2-bromo-LSD
4.76	Single	9B9Z	A1AKO	9B9Z-CB₁-A1AKO
4.76	Single	9DQH	EP-2825	9DQH-MRGPRD-EP-2825-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	9DYD	Asenapine	9DYD-5-HT_1A-Asenapine-Go/β1/γ2
4.76	Single	9DYF	Asenapine	9DYF-5-HT_1A-Asenapine-Gi1/β1/γ2
4.76	Single	9EE8	Adenosine	9EE8-A_2A-Adenosine-Gs/β1/γ2
4.76	Single	9F33	FOB02-04A	9F33-D₃-FOB02-04A-Go/β1/γ2
4.76	Single	9F34	FOB02-04A	9F34-D₃-FOB02-04A-Go/β1/γ2
4.76	Single	9I52	A1IZU	9I52-D₁-A1IZU-Gs/β1/γ2
4.76	Single	9K07	DSO-5a	9K07-BB₃-DSO-5a-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.76	Single	9KPF	SA0	9KPF-TAS2R16-SA0-Gi1/β1/γ2
4.76	Single	9MQK	Isoquinuclidine	9MQK-κ-Isoquinuclidine
4.76	Consensus	5ht1_on	Orthosteric Ligand	5ht1a_on 5ht1d_on 5ht1e_on 5ht1f_on
4.76	Consensus	5ht1_on_gp	Orthosteric Ligand	5ht1a_on_gp 5ht1d_on_gp 5ht1e_on_gp 5ht1f_on_gp
4.76	Consensus	5ht1e_on_gp	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
4.76	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
4.76	Consensus	5ht5_on_gp	Orthosteric Ligand	5ht5a_on_gp
4.76	Consensus	5ht5a_on_gp	Orthosteric Ligand	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
4.76	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
4.76	Consensus	adrenergic_off	Orthosteric Ligand	alpha_off beta_off
4.76	Consensus	adrenergic_on_gp	Orthosteric Ligand	alpha_on_gp beta_on_gp
4.76	Consensus	alpha2c_off	Orthosteric Ligand	6KUW-α_2c-PubChem 57213234
4.76	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
4.76	Consensus	alpha_on_gp	Orthosteric Ligand	alpha1_on_gp alpha2_on_gp
4.76	Consensus	amine_off	Orthosteric Ligand	5ht_off adrenergic_off dopamine_off histamine_off muscarinic_off
4.76	Consensus	amine_offon	Orthosteric Ligand	amine_off amine_on
4.76	Consensus	amine_offon_gp	Orthosteric Ligand	amine_on_gp amine_off
4.76	Consensus	amine_on	Orthosteric Ligand	5ht_on adrenergic_on dopamine_on histamine_on muscarinic_on trace-amine_on
4.76	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
4.76	Consensus	beta2_off	Orthosteric Ligand	2RH1-β₂-S-Carazolol 6PS3-β₂-S-Carvedilol 6PS5-β₂-S-Propranolol 3D4S-β₂-Timolol 3NY8-β₂-ICI118-551 3NY9-β₂-ICI118-551 6PRZ-β₂-S-Alprenolol
4.76	Consensus	beta_off	Orthosteric Ligand	beta1_off beta2_off
4.76	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
4.76	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
4.76	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
4.76	Consensus	d4_on	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
4.76	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
4.76	Consensus	ep_off	Orthosteric Ligand	ep4_off
4.76	Consensus	gi_adrenergic	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
4.76	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
4.76	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_trace-amine
4.76	Consensus	h1_off	Orthosteric Ligand	8X63-H₁-Mepyramine 3RZE-H₁-Cidoxepin 8X5Y-H₁-Astemizole
4.76	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
4.76	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.76	Consensus	trace-amine_on	Orthosteric Ligand	ta1_on
4.55	Single	3P0G	BI167107	3P0G-β₂-BI167107
4.55	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
4.55	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/β1/γ2
4.55	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
4.55	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
4.55	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
4.55	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
4.55	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
4.55	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
4.55	Single	5D5A	S-Carazolol	5D5A-β₂-S-Carazolol
4.55	Single	5D5B	S-Carazolol	5D5B-β₂-S-Carazolol
4.55	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
4.55	Single	5XRA	AM11542	5XRA-CB₁-AM11542
4.55	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/β1/γ2
4.55	Single	6E59	L-760735	6E59-NK₁-L-760735
4.55	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
4.55	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
4.55	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
4.55	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
4.55	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
4.55	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
4.55	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/β1/γ2
4.55	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
4.55	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
4.55	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
4.55	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
4.55	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
4.55	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/β1/γ2
4.55	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2
4.55	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/β1/γ2
4.55	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
4.55	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/β1/γ2
4.55	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/β1/γ2
4.55	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/β1/γ2
4.55	Single	7P2L	4YI	7P2L-mGlu₅-4YI
4.55	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
4.55	Single	7R0C	AVP	7R0C-V₂-AVP-Arrestin2
4.55	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/β1/γ2
4.55	Single	7W6P	N-pyridin-4-ylisoquinolin-4-amine	7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2
4.55	Single	7W7E	PubChem 164946676	7W7E-α_2a-PubChem 164946676-Go/β1/γ2
4.55	Single	7WV9	CP55940	7WV9-CB₁-CP55940-ZCZ011-Gi2/β1/γ2
4.55	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2
4.55	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/β1/γ2
4.55	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/β1/γ2
4.55	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/β1/γ2
4.55	Single	8E0G	BU72	8E0G-μ-BU72
4.55	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/β1/γ2
4.55	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/β1/γ2
4.55	Single	8FMZ	Neurotensin/Neuromedin-N	8FMZ-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.55	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
4.55	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/β1/γ2
4.55	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
4.55	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/β1/γ2
4.55	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
4.55	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
4.55	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	8JD5	JNJ-40411813; ADX88178	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
4.55	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/β1/γ2
4.55	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2
4.55	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/β1/γ2
4.55	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/β1/γ2
4.55	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/β1/γ2
4.55	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
4.55	Single	8VVE	norBNI	8VVE-κ-norBNI-Gi1/β1/γ2
4.55	Single	8VVF	JDTic	8VVF-κ-JDTic-Gi1/β1/γ2
4.55	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/β1/γ2
4.55	Single	8XVL	Zibotentan	8XVL-ET_A-Zibotentan
4.55	Single	8XZI	CMF-019	8XZI-Apelin-CMF-019-Gi1/β1/γ2
4.55	Single	8Y73	Peptide	8Y73-μ-Peptide-MPAM-15-Gi1/β1/γ2
4.55	Single	8ZW0	PGD2	8ZW0-DP₁-PGD2-Gs/β1/γ2
4.55	Single	9BJK	Naloxone	9BJK-μ-Naloxone-NAM
4.55	Single	9I54	A1IZV	9I54-D₁-A1IZV-Gs/β1/γ2
4.55	Single	9IJD	Carazolol	9IJD-β₃-Carazolol-chim(NtGi1-Gs)/β1/γ2
4.55	Single	9JMC	DS-3801b	9JMC-Motilin-DS-3801b-chim(Gs-CtGq)/β1/γ2
4.55	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
4.55	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
4.55	Consensus	5ht_off	Orthosteric Ligand	5ht2_off 5ht1_off
4.55	Consensus	a2_on	Orthosteric Ligand	a2b_on
4.55	Consensus	a2_on_gp	Orthosteric Ligand	a2b_on_gp
4.55	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
4.55	Consensus	a2b_on_gp	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
4.55	Consensus	amine_on_gp	Orthosteric Ligand	5ht_on_gp adrenergic_on_gp dopamine_on_gp histamine_on_gp muscarinic_on_gp trace-amine_on_gp
4.55	Consensus	beta1_off	Orthosteric Ligand	2VT4-β₁-Cyanopindolol 2YCW-β₁-S-Carazolol 2YCZ-β₁-Iodocyanopindolol 5A8E-β₁-7-Methylcyanopindolol-Na 3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na 3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
4.55	Consensus	beta2_on	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2
4.55	Consensus	beta2_on_gp	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2
4.55	Consensus	d1_on_gp	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
4.55	Consensus	d4_on_gp	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
4.55	Consensus	d5_on_gp	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
4.55	Consensus	gi_5ht	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8W8B-5-HT_1A-SEP-363856-Gi1/β1/γ2 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E32-5-HT_1D-Serotonin-Gi1/β1/γ2 7XTA-5-HT₄-Serotonin-Gi1/β1/γ2 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2
4.55	Consensus	gi_dopamine	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 7CMV-D₃-PD128907-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2
4.55	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
4.55	Consensus	gs_adrenergic	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2 7JJO-β₁-Isoprenaline-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2 8DCR-β₁-Dobutamine-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7DH5-β₃-Mirabegron-Gs/β1/γ2
4.55	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2
4.55	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
4.55	Consensus	h4_on_gp	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
4.55	Consensus	m1_on_gp	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
4.55	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Consensus	nk2_on_gp	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
4.55	Consensus	ta1_on_gp	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.55	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
4.55	Consensus	trace-amine_on_gp	Orthosteric Ligand	ta1_on_gp
4.35	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
4.35	Single	3D4S	Timolol	3D4S-β₂-Timolol
4.35	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
4.35	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
4.35	Single	4LDE	BI167107	4LDE-β₂-BI167107
4.35	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
4.35	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
4.35	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
4.35	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
4.35	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
4.35	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
4.35	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
4.35	Single	6H7N	S-Xamoterol	6H7N-β₁-S-Xamoterol
4.35	Single	6H7O	Cyanopindolol	6H7O-β₁-Cyanopindolol
4.35	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
4.35	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
4.35	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/β1/γ2
4.35	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/β1/γ2
4.35	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
4.35	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/β1/γ2
4.35	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
4.35	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
4.35	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
4.35	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
4.35	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
4.35	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
4.35	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/β1/γ2
4.35	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
4.35	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/β1/γ2
4.35	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
4.35	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
4.35	Single	8FYE	4-F,5-MeO-PyrT	8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1
4.35	Single	8FYT	LSD	8FYT-5-HT_1A-LSD-Gi1/β1/γ1
4.35	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/β1/γ2
4.35	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
4.35	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
4.35	Single	8JWY	2-118	8JWY-A_2A-2-118
4.35	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
4.35	Single	8W1V	PubChem 171716265	8W1V-β₂-PubChem 171716265
4.35	Single	9AU0	BW245C	9AU0-DP₁-BW245C-Gs/β1/γ2
4.35	Single	9BJK	NAM	9BJK-μ-Naloxone-NAM
4.35	Single	9EBI	Piclidenoson	9EBI-A_3A-Piclidenoson-chim(NtGi1L-Gs-CtGi1)/β1/γ2
4.35	Single	9GL2	Befiradol	9GL2-5-HT_1A-Befiradol-Gs/β1/γ2
4.35	Single	9M4Q	Doxazosin	9M4Q-Alpha1A-Doxazosin
4.35	Single	9MQL	Isoquinuclidine	9MQL-κ-Isoquinuclidine
4.35	Consensus	5ht1a_on	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
4.35	Consensus	5ht1a_on_gp	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
4.35	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
4.35	Consensus	5ht1f_on_gp	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
4.35	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off
4.35	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin
4.35	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
4.35	Consensus	beta3_on_gp	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
4.35	Consensus	beta_on	Orthosteric Ligand	beta1_on beta2_on beta3_on
4.35	Consensus	beta_on_gp	Orthosteric Ligand	beta1_on_gp beta2_on_gp beta3_on_gp
4.35	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
4.35	Consensus	d2_on_gp	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
4.35	Consensus	gi_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2 7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
4.35	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
4.35	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
4.35	Consensus	m4_on_gp	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
4.35	Consensus	mop_on	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
4.35	Consensus	mop_on_gp	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
4.35	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
4.35	Consensus	nk1_off	Orthosteric Ligand	6HLP-NK₁-Netupitant 6HLO-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
4.35	Consensus	opioid_off	Orthosteric Ligand	mop_off nop_off dop_off kop_off
4.35	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
4.17	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
4.17	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
4.17	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
4.17	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
4.17	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
4.17	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
4.17	Single	5X93	K-8794	5X93-ET_B-K-8794
4.17	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
4.17	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
4.17	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/β1/γ2
4.17	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
4.17	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
4.17	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
4.17	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
4.17	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
4.17	Single	7EZC	UKA	7EZC-A_2A-UKA
4.17	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
4.17	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2
4.17	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2
4.17	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.17	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
4.17	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
4.17	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
4.17	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/β1/γ2
4.17	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
4.17	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.17	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/β1/γ2
4.17	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/β1/γ2
4.17	Single	8FN0	Neurotensin/Neuromedin-N	8FN0-NTS₁-Neurotensin/Neuromedin-N-SBI-553-chim(NtGi1-Go)/β1/γ2
4.17	Single	8ID8	TUG-891	8ID8-FFA4-TUG-891-Gi1/β1/γ2
4.17	Single	8S2T	Isoprenaline	8S2T-β₁-Isoprenaline-chim(NtGi1-Gs)/β1/γ2
4.17	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.17	Single	9AS0	2-bromo-LSD	9AS0-5-HT_2A-2-bromo-LSD-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Single	9C0K	Exendin-4	9C0K-GLP-1-Exendin-4-Gs/β1/γ2
4.17	Single	9CGJ	C6-Quino	9CGJ-δ-C6-Quino-Gi1/β1/γ2
4.17	Single	9DYE	Buspirone	9DYE-5-HT_1A-Buspirone-Go/β1/γ2
4.17	Single	9IZF	NKP	9IZF-LPA₁-NKP-Gi1/β1/γ2
4.17	Single	9M54	Neuropeptide VF	9M54-NPFF2-Neuropeptide VF-Gi1/β1/γ2
4.17	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
4.17	Consensus	beta1_on	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
4.17	Consensus	beta1_on_gp	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
4.17	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
4.17	Consensus	cck_on_gp	Orthosteric Ligand	ccka_on_gp cckb_on_gp
4.17	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
4.17	Consensus	ccka_on_gp	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
4.17	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
4.17	Consensus	endothelin_off	Orthosteric Ligand	etb_off
4.17	Consensus	etb_off	Orthosteric Ligand	5X93-ET_B-K-8794 5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500
4.17	Consensus	kop_on_gp	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
4.17	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
4.00	Single	3NY9	ICI118-551	3NY9-β₂-ICI118-551
4.00	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
4.00	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
4.00	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/β1/γ2
4.00	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
4.00	Single	6PT3	DPI-287	6PT3-δ-DPI-287
4.00	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
4.00	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2
4.00	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
4.00	Single	7XY6	BAY 60-6583	7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
4.00	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2
4.00	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
4.00	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2
4.00	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs
4.00	Single	8X3L	XWD	8X3L-CB₂-XWD-Gi1/β1/γ2
4.00	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
4.00	Single	8Y72	Peptide	8Y72-μ-Peptide-BMS-986122-Gi1/β1/γ2
4.00	Single	9CGK	C5-Quino	9CGK-δ-C5-Quino-Gi1/β1/γ2
4.00	Single	9JF4	PD168368	9JF4-BB₁-PD168368
4.00	Single	9M0R	Neuropeptide VF	9M0R-NPFF1-Neuropeptide VF-Gi1/β1/γ2
4.00	Single	9MD1	Buspirone	9MD1-5-HT_1A-Buspirone-Gz/β1/γ2
4.00	Single	9V2N	Macimorelin	9V2N-Ghrelin-Macimorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
4.00	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
4.00	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
4.00	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
4.00	Consensus	nmur1_on	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
4.00	Consensus	sst2_on	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
4.00	Consensus	sst2_on_gp	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
3.85	Single	4AMJ	S-Carvedilol	4AMJ-β₁-S-Carvedilol
3.85	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
3.85	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
3.85	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
3.85	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/β1/γ1
3.85	Single	7QA8	Peptide	7QA8-STE2-Peptide
3.85	Single	7QA8	Peptide	7QA8-STE2-Peptide
3.85	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
3.85	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2
3.85	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/β1/γ2
3.85	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/β1/γ2
3.85	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/β1/γ2
3.85	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/β1/γ2
3.85	Single	8FYL	Vilazodone	8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
3.85	Single	8G59	TUG-891	8G59-FFA4-TUG-891-chim(Gi1-CtGq)/β1/γ2
3.85	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
3.85	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
3.85	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
3.85	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
3.85	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
3.85	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
3.85	Single	8PKM	Befiradol	8PKM-5-HT_1A-Befiradol-Gi1/β1/γ1
3.85	Single	8YWF	Retatrutide	8YWF-GLP-1-Retatrutide-chim(NtGi1-Gs)/β1/γ2
3.85	Single	8ZCJ	Pasireotide	8ZCJ-SST5-Pasireotide-Gi1/β1/γ1
3.85	Single	8ZSP	LSD	8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
3.85	Single	9BKJ	Cholecystokinin-8	9BKJ-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Single	9M4T	Silodosin	9M4T-Alpha1A-Silodosin
3.85	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
3.85	Consensus	mop_off	Orthosteric Ligand	4DKL-μ-β-Funaltrexamine 8QOT-μ-Nanobody-E 7UL4-μ-Alvimopan
3.85	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Consensus	nmur1_on_gp	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
3.85	Consensus	nop_on_gp	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
3.85	Consensus	somatostatin_off	Orthosteric Ligand	sst2_off
3.70	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
3.70	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
3.70	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
3.70	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/β1/γ2
3.70	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
3.70	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
3.70	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/β1/γ2
3.70	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
3.70	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
3.70	Consensus	dop_on_gp	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
3.70	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
3.70	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
3.70	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
3.70	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
3.70	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
3.57	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/β1/γ2
3.57	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
3.57	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.57	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
3.57	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/β1/γ2
3.57	Single	8K6N	Pro-neuropeptide-Y	8K6N-Y₂-Pro-neuropeptide-Y-Gi2/β1/γ1
3.57	Single	8XGU	TAK448	8XGU-Kiss1-TAK448-Gi1/β1/γ2
3.57	Single	9B5Y	Long-Acting PTH	9B5Y-PTH1-Long-Acting PTH-chim(NtGi1-Gq)/β1/γ2
3.57	Single	9M1O	Morphine-Modulating Neuropeptide B	9M1O-NPFF2-Morphine-Modulating Neuropeptide B-Gi1/β1/γ2
3.57	Single	9U4W	Gonadoliberin-1	9U4W-GnRH₁-Gonadoliberin-1-chim(NtGi1L-Gs-CtGq)/β1/γ2
3.57	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
3.57	Consensus	class-b1_class-b2_cons_on	Orthosteric Ligand	class-b1_on class-b2_on
3.57	Consensus	class-b1_class-b2_cons_on_gp	Orthosteric Ligand	class-b1_on_gp class-b2_on_gp
3.57	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
3.57	Consensus	gi_somatostatin	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
3.57	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
3.57	Consensus	gs_class-a	Orthosteric Ligand	gs_peptide gs_nucleotide gs_amine
3.45	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/β1/γ2
3.45	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
3.45	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
3.45	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
3.45	Single	7T10	Somatostatin-14	7T10-SST2-Somatostatin-14-Gi3/β1/γ2
3.45	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
3.45	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/β1/γ2
3.45	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2
3.45	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
3.45	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
3.45	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
3.45	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
3.45	Single	8WST	Pro-MCH	8WST-MCH2-Pro-MCH-chim(NtGi1L-Gs-CtGq)/β1/γ2
3.45	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
3.45	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ2
3.45	Single	9BKK	Cholecystokinin-8	9BKK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
3.45	Single	9BUD	Cagrilintide	9BUD-CT-Cagrilintide-Gs/β1/γ2
3.45	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
3.45	Consensus	fpr2-alx_on_gp	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
3.45	Consensus	mc5_on_gp	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
3.45	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
3.33	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
3.33	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
3.33	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
3.33	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
3.33	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
3.33	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
3.33	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
3.33	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
3.33	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
3.33	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
3.33	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.33	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/β1/γ2
3.33	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/β1/γ2
3.33	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
3.33	Single	8XGO	TAK448	8XGO-Kiss1-TAK448-chim(NtGi1-Gq)/β1/γ2
3.33	Single	9JFY	hNPSF	9JFY-NPFF2-hNPSF-Gi1/β1/γ2
3.33	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
3.33	Consensus	pac_on	Orthosteric Ligand	pac1_on
3.33	Consensus	vpac1_on	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
3.33	Consensus	vpac_on	Orthosteric Ligand	vpac1_on vpac2_on
3.23	Single	6NBF	Long-Acting PTH Analog	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
3.23	Single	6NBI	Long-Acting PTH Analog	6NBI-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
3.23	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/β1/γ2
3.23	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/β1/γ2
3.23	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ2
3.23	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
3.23	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/β1/γ2
3.23	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
3.23	Single	9BLB	Cagrilintide backbone (non-acylated)	9BLB-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
3.23	Single	9BP3	Cagrilintide	9BP3-CT (AMY1)-Cagrilintide-Gs/β1/γ2; RAMP1
3.23	Single	9BUB	Cagrilintide	9BUB-CT-Cagrilintide-Gs/β1/γ2
3.23	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
3.23	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
3.23	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
3.23	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
3.23	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
3.23	Consensus	npy4_on_gp	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
3.23	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
3.23	Consensus	pac_on_gp	Orthosteric Ligand	pac1_on_gp
3.23	Consensus	secretin_on	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
3.23	Consensus	vpac1_on_gp	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
3.23	Consensus	vpac_on_gp	Orthosteric Ligand	vpac1_on_gp vpac2_on_gp
3.12	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
3.12	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/β1/γ2
3.12	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
3.12	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2
3.12	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
3.12	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
3.12	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2
3.12	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
3.12	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
3.12	Single	8W8W	Alpha-MSH	8W8W-MC₃-α-MSH-Ca-Gs/β1/γ2
3.12	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
3.12	Single	9KDF	RES-701-3	9KDF-ET_B-RES-701-3
3.12	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
3.12	Consensus	glp2_on_gp	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
3.12	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
3.12	Consensus	glp_on_gp	Orthosteric Ligand	glp1_on_gp glp2_on_gp
3.12	Consensus	secretin_on_gp	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
3.03	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
3.03	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
3.03	Single	6NBH	Long-Acting PTH Analog	6NBH-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
3.03	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
3.03	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
3.03	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
3.03	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
3.03	Single	7VGX	Neuropeptide-Y	7VGX-Y₁-Neuropeptide-Y-Gi1/β1/γ2
3.03	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
3.03	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
3.03	Single	8Y52	BA1	8Y52-BB₃-BA1-chim(NtGi1-Gs-CtGq)/β1/γ2
3.03	Single	9BYO	Exendin-3	9BYO-GLP-1-Exendin-3-Gs/β1/γ2
3.03	Consensus	ctlike_on_gp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
3.03	Consensus	etb_on	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
3.03	Consensus	vip-pacap_on	Orthosteric Ligand	vpac_on pac_on
3.03	Consensus	vip-pacap_on_gp	Orthosteric Ligand	vpac_on_gp pac_on_gp
2.94	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
2.94	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
2.94	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
2.94	Consensus	bb2_on_gp	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
2.94	Consensus	bombesin_on	Orthosteric Ligand	bb2_on
2.94	Consensus	bombesin_on_gp	Orthosteric Ligand	bb2_on_gp
2.94	Consensus	class-a_class-b1_cons_on	Orthosteric Ligand	class-a_on class-b1_on
2.94	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
2.94	Consensus	gip_on	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
2.94	Consensus	gip_on_gp	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
2.94	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
2.86	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/β1/γ1
2.86	Single	8FLU	Long-Acting PTH	8FLU-PTH1-Long-Acting PTH-Gs/β1/γ2
2.86	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/β1/γ2
2.86	Consensus	etb_on_gp	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
2.86	Consensus	glp1_on	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
2.78	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
2.78	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
2.78	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
2.78	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
2.78	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
2.78	Consensus	glp1_on_gp	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
2.70	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
2.70	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
2.70	Consensus	class-a_class-b1_cons_on_gp	Orthosteric Ligand	class-a_on_gp class-b1_on_gp
2.70	Consensus	glucagon_on	Orthosteric Ligand	glp_on gluc_on secretin_on gip_on
2.70	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
2.63	Consensus	gluc_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
2.63	Consensus	glucagon_on_gp	Orthosteric Ligand	glp_on_gp gluc_on_gp secretin_on_gp gip_on_gp
2.63	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
2.56	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
2.50	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
2.50	Consensus	pth2_on_gp	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
2.38	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:K74	4.78	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:R78	5.15	1	Yes	Yes	0	4	0	1
L:L:?1	R:R:S159	8.91	1	Yes	Yes	0	9	0	1
L:L:?1	R:R:T182	5	1	Yes	Yes	0	8	0	1
L:L:?1	R:R:Y230	31.82	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:S313	3.82	1	Yes	No	0	6	0	1
L:L:?1	R:R:K405	8.37	1	Yes	Yes	0	4	0	1
R:R:K74	R:R:P56	8.36	1	Yes	No	5	5	1	2
R:R:P56	R:R:S157	7.13	1	No	Yes	5	5	2	2
R:R:K71	R:R:K74	15.8	1	No	Yes	5	5	2	1
R:R:K74	R:R:R78	9.9	1	Yes	Yes	5	4	1	1
R:R:K74	R:R:S157	4.59	1	Yes	Yes	5	5	1	2
R:R:E287	R:R:K74	6.75	0	No	Yes	3	5	2	1
R:R:R78	R:R:S157	9.22	1	Yes	Yes	4	5	1	2
R:R:R78	R:R:Y179	9.26	1	Yes	Yes	4	8	1	2
R:R:E403	R:R:R78	6.98	1	Yes	Yes	5	4	2	1
R:R:K405	R:R:R78	9.9	1	Yes	Yes	4	4	1	1
R:R:S157	R:R:Y179	7.63	1	Yes	Yes	5	8	2	2
R:R:S159	R:R:S181	6.52	1	Yes	No	9	8	1	2
R:R:S159	R:R:Y230	6.36	1	Yes	Yes	9	7	1	1
R:R:A180	R:R:K405	6.42	0	No	Yes	6	4	2	1
R:R:D202	R:R:T182	8.67	1	Yes	Yes	8	8	2	1
R:R:T182	R:R:Y230	3.75	1	Yes	Yes	8	7	1	1
R:R:D312	R:R:T182	5.78	1	Yes	Yes	8	8	2	1
R:R:D202	R:R:Y230	6.9	1	Yes	Yes	8	7	2	1
R:R:D202	R:R:F284	3.58	1	Yes	Yes	8	8	2	2
R:R:G231	R:R:Y230	4.35	0	No	Yes	8	7	2	1
R:R:F284	R:R:Y230	4.13	1	Yes	Yes	8	7	2	1
R:R:S311	R:R:Y230	5.09	1	No	Yes	8	7	2	1
R:R:S313	R:R:Y230	3.82	1	No	Yes	6	7	1	1
R:R:F284	R:R:S311	13.21	1	Yes	No	8	8	2	2
R:R:S313	R:R:W314	6.18	1	No	Yes	6	7	1	2
R:R:F408	R:R:K405	6.2	1	Yes	Yes	7	4	2	1
R:R:A183	R:R:S159	3.42	0	No	Yes	7	9	2	1
L:L:?1	R:R:G158	2.9	1	Yes	No	0	4	0	1
R:R:G75	R:R:K74	1.74	0	No	Yes	5	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
100.00	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
100.00	Single	6D35	Cholesterol	6D35-SMO-Cholesterol
100.00	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
100.00	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
100.00	Single	6UO8	SKF97541	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
100.00	Single	6UO9	SKF97541	6UO9-GABA_B1, GABA_B2-SKF97541
100.00	Single	6W2X	PubChem 5311042	6W2X-GABA_B1, GABA_B2-PubChem 5311042
100.00	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042
100.00	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042
100.00	Single	7C7Q	Baclofen	7C7Q-GABA_B1, GABA_B2-Baclofen-BHFF
100.00	Single	7C7S	CGP54626	7C7S-GABA_B1, GABA_B2-CGP54626
100.00	Single	7CUM	CGP54626	7CUM-GABA_B1, GABA_B2-CGP54626
100.00	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DGE	Quisqualate	7DGE-mGlu1; mGlu1-Quisqualate
100.00	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
100.00	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
100.00	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
100.00	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
100.00	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
100.00	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
100.00	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
100.00	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
100.00	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
100.00	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
100.00	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/β1/γ2
100.00	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/β1/γ2
100.00	Single	7EB2	Baclofen	7EB2-GABAB2; GABAB1-Baclofen-rac-BHFF-Gi1/β1/γ2
100.00	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
100.00	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
100.00	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
100.00	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
100.00	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
100.00	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
100.00	Single	7FIH	hCG	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
100.00	Single	7FII	hCG	7FII-LH-hCG-chim(NtGi1-Gs)/β1/γ2
100.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
100.00	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
100.00	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
100.00	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
100.00	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
100.00	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
100.00	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
100.00	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
100.00	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
100.00	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
100.00	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
100.00	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7T9N	M22 Fab	7T9N-TSH-M22 Fab-DPPC-Gs/β1/γ2
100.00	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
100.00	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
100.00	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
100.00	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
100.00	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
100.00	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
100.00	Single	7XW6	M22 Fab	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
100.00	Single	7XW7	K1-70	7XW7-TSH-K1-70
100.00	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
100.00	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
100.00	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
100.00	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
100.00	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
100.00	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
100.00	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
100.00	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
100.00	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
100.00	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
100.00	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
100.00	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
100.00	Single	8JD0	Glutamate	8JD0-mGlu2; mGlu3-Glutamate-NAM563
100.00	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
100.00	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
100.00	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
100.00	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
100.00	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-JNJ-40411813-Gi1/β1/γ2
100.00	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-JNJ-40411813-Gi1/β1/γ2
100.00	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
100.00	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
100.00	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
100.00	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
100.00	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-VU0364770-Gi3/β1/γ2
100.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
100.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
100.00	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine-chim(NtGi1-Gq)/β1/γ2
100.00	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
100.00	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
100.00	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
100.00	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
100.00	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
100.00	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
100.00	Single	8TQB	Ca; PAM VU6023326	8TQB-mGlu3; mGlu3-Ca; PAM VU6023326-Ca
100.00	Single	8TQB	Ca; PAM VU6023326	8TQB-mGlu3; mGlu3-Ca; PAM VU6023326-Ca
100.00	Single	8TR0	LY341495	8TR0-mGlu3; mGlu3-LY341495
100.00	Single	8TR0	LY341495	8TR0-mGlu3; mGlu3-LY341495
100.00	Single	8TR2	Ca; LY379268	8TR2-mGlu3; mGlu3-Ca; LY379268-Ca
100.00	Single	8TR2	Ca; LY379268	8TR2-mGlu3; mGlu3-Ca; LY379268-Ca
100.00	Single	8TRC	LY341495	8TRC-mGlu3; mGlu3-LY341495
100.00	Single	8TRC	LY341495	8TRC-mGlu3; mGlu3-LY341495
100.00	Single	8TRD	LY341495	8TRD-mGlu3; mGlu3-LY341495
100.00	Single	8TRD	LY341495	8TRD-mGlu3; mGlu3-LY341495
100.00	Single	8WG9	(2S)-2-amino-4-phosphonobutanoic acid	8WG9-mGlu4; mGlu2-(2S)-2-amino-4-phosphonobutanoic acid
100.00	Single	8WGB	Glutammate	8WGB-mGlu4; mGlu2-Glutammate-VU0155041-Gi3/β1/γ2
100.00	Single	8WGB	Glutammate	8WGB-mGlu4; mGlu2-Glutammate-VU0155041-Gi3/β1/γ2
100.00	Single	8WGC	LY379268	8WGC-mGlu4; mGlu2-LY379268
100.00	Single	8WGD	WAG; WA6	8WGD-mGlu4; mGlu2-WAG; WA6
100.00	Single	8WGD	WAG; WA6	8WGD-mGlu4; mGlu2-WAG; WA6
100.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
100.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
100.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
100.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
100.00	Single	8WVX	Norrin	8WVX-LGR4-Norrin
100.00	Single	8WVY	Norrin	8WVY-LGR4-Norrin
100.00	Single	8X0B	Quisqualate	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0B	Quisqualate	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0C	Quisqualate	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0C	Quisqualate	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0D	Quisqualate	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0D	Quisqualate	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0E	Quisqualate	8X0E-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0E	Quisqualate	8X0E-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0F	Quisqualate	8X0F-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0F	Quisqualate	8X0F-mGlu5; mGlu5-Quisqualate-VU0424465
100.00	Single	8X0G	Quisqualate	8X0G-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0G	Quisqualate	8X0G-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0H	Quisqualate	8X0H-mGlu5; mGlu5-Quisqualate
100.00	Single	8X0H	Quisqualate	8X0H-mGlu5; mGlu5-Quisqualate
100.00	Single	8XUM	R-spondin-2	8XUM-LGR4-R-spondin-2
100.00	Single	9ASB	Ca	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AVG	Ca	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
100.00	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
100.00	Single	9AVL	Ca	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
100.00	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
100.00	Single	9AVL	Ca	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
100.00	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
100.00	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
100.00	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
100.00	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
100.00	Single	9C1P	Ca	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
100.00	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
100.00	Single	9C1P	Ca	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
100.00	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
100.00	Single	9C2F	Ca	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
100.00	Single	9C2F	Ca; Ca; Tryptophan; '54149; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
100.00	Single	9C2F	Ca	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
100.00	Single	9C2F	Ca; Ca; Tryptophan; '54149; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
100.00	Single	9II2	Glutamate	9II2-mGlu3; mGlu3-Glutamate-Arrestin2
100.00	Single	9II2	Glutamate	9II2-mGlu3; mGlu3-Glutamate-Arrestin2
100.00	Single	9II3	Glutamate	9II3-mGlu3; mGlu3-Glutamate-Arrestin2
100.00	Single	9II3	Glutamate	9II3-mGlu3; mGlu3-Glutamate-Arrestin2
100.00	Single	9KHH	Norrin	9KHH-LGR4-Norrin
100.00	Single	9S37	NB21	9S37-LGR4-NB21
100.00	Single	9UTB	Sucralose	9UTB-TAS1R2; TAS1R3-Sucralose
50.00	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
50.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
50.00	Single	9ASB	Ca	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
50.00	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
50.00	Single	9AVG	Ca	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
50.00	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
50.00	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
50.00	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
33.33	Single	7KNU	Calcitonin gene-related peptide-1	7KNU-CT Like-Calcitonin gene-related peptide-1-RAMP1
33.33	Single	7T9M	CS-17 Antibody	7T9M-TSH-CS-17 Antibody
25.00	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
25.00	Single	7FIG	hCG	7FIG-LH-hCG-chim(NtGi1L-Gs)/β1/γ2
25.00	Single	7UTZ	TR1402	7UTZ-TSH-TR1402-DPPC-Gs/β1/γ2
25.00	Single	7XW5	TSH	7XW5-TSH-TSH-ML109-Gs/β1/γ2
25.00	Single	7ZI0	Cholesterol	7ZI0-SMO-SAG-Cholesterol
20.00	Single	5L7D	Cholesterol	5L7D-SMO-Cholesterol
20.00	Single	7T9I	TSH	7T9I-TSH-TSH-Gs/β1/γ2
20.00	Single	8HS2	Fab046	8HS2-GPR20-Fab046
20.00	Single	8I2G	Glycoprotein hormones alpha chain	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
20.00	Single	8X9S	5alpha-DHT	8X9S-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
20.00	Single	9IV2	5alpha-DHT	9IV2-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
16.67	Single	6XBM	5LWE	6XBM-SMO-5LWE-Gi1/β1/γ2
16.67	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Gi1/β1/γ2
16.67	Consensus	p2y_off	Orthosteric Ligand	p2y1_off
14.29	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
14.29	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
14.29	Single	8JEF	(3S)-3-hydroxyoctanoic acid	8JEF-HCA₃-(3S)-3-hydroxyoctanoic acid-Gi1/β1/γ2
14.29	Single	8JPS	CCL7	8JPS-ACKR1-CCL7
14.29	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
14.29	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
12.50	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
12.50	Single	6LI0	C17	6LI0-GPR52-C17
12.50	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/β1/γ2
12.50	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/β1/γ2
12.50	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab
12.50	Single	9B9Y	7DY	9B9Y-CB₁-7DY
12.50	Single	9E7R	GB88	9E7R-PAR2-GB88-chim(NtGi1L-Gs-CtGq)/β1/γ2
11.11	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
11.11	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
11.11	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
11.11	Single	5U09	Taranabant	5U09-CB₁-Taranabant
11.11	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/β1/γ2
11.11	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
11.11	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/β1/γ2
11.11	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
11.11	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
11.11	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/β1/γ2
11.11	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/β1/γ2
11.11	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/β1/γ2
11.11	Single	8HMP	C17	8HMP-GPR52-C17-Gs/β1/γ2
11.11	Single	8U4S	REGN7663-Fab	8U4S-CXCR4-REGN7663-Fab
11.11	Single	8U4T	REGN7663-Fab	8U4T-CXCR4-REGN7663-Fab
11.11	Single	8XXX	CXCL6	8XXX-CXCR2-CXCL6-Go/β1/γ2
11.11	Single	8YYW	Alpha-ketoglutarate	8YYW-Oxoglutarate-α-ketoglutarate-α-ketoglutarate-chim(Gi1-CtGq)/β1/γ2
11.11	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
11.11	Consensus	ccr6_on_gp	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
11.11	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
11.11	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
11.11	Consensus	p2y1_on	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
11.11	Consensus	s1p1_off	Orthosteric Ligand	3V2W-S1P₁-PubChem 51892645
10.00	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
10.00	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
10.00	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2
10.00	Single	7UTZ	DPPC	7UTZ-TSH-TR1402-DPPC-Gs/β1/γ2
10.00	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
10.00	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
10.00	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
10.00	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	9BA0	A1AKN	9BA0-CB₁-A1AKN
10.00	Single	9K0K	UTP	9K0K-P2Y₄-UTP-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	9K0X	ATP	9K0X-P2Y₂-ATP-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	9K20	ATP	9K20-P2Y₂-ATP-chim(NtGi1-Go)/β1/γ2
10.00	Single	9M2F	Neuropeptide FF	9M2F-NPFF1-Neuropeptide FF-Gi1/β1/γ2
10.00	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
10.00	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
10.00	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
10.00	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
10.00	Consensus	p2y1_on_gp	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
9.09	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
9.09	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
9.09	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
9.09	Single	6D27	CAY10471	6D27-DP₂-CAY10471
9.09	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/β1/γ2
9.09	Single	6XBM	5LWE	6XBM-SMO-5LWE-Gi1/β1/γ2
9.09	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
9.09	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
9.09	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/β1/γ2
9.09	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
9.09	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
9.09	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
9.09	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/β1/γ2
9.09	Single	7VIF	S-FTY720-P	7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2
9.09	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
9.09	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
9.09	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
9.09	Single	9IVG	GLP-1 (Truncated)	9IVG-GLP-1-GLP-1 (Truncated)-chim(NtGi1-Gs)/β1/γ2
9.09	Consensus	cxcr1_on_gp	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
9.09	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off paf_off lpl_off prostanoid_off leukotriene_off
9.09	Consensus	nucleotide_offon	Orthosteric Ligand	nucleotide_off nucleotide_on
9.09	Consensus	nucleotide_offon_gp	Orthosteric Ligand	nucleotide_on_gp nucleotide_off
8.33	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
8.33	Single	5C1M	BU72	5C1M-μ-BU72
8.33	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
8.33	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
8.33	Single	7BB7	AVP	7BB7-V₂-AVP-Gs/β1/γ2
8.33	Single	7C4S	S1P	7C4S-S1P₃-S1P
8.33	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/β1/γ2
8.33	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/β1/γ2
8.33	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
8.33	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/β1/γ2
8.33	Single	8ID4	Linoleic acid	8ID4-FFA4-Linoleic acid-Gi1/β1/γ2
8.33	Single	8YIC	SAR247799	8YIC-S1P₁-SAR247799-Gi1/β1/γ2
8.33	Single	8ZPT	PrRP20	8ZPT-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	8ZYT	Neurotensin peptide 8-13	8ZYT-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
8.33	Single	9B9Z	A1AKO	9B9Z-CB₁-A1AKO
8.33	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
8.33	Consensus	cxcr2_on_gp	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
8.33	Consensus	lpa1_on	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
8.33	Consensus	lpa1_on_gp	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
8.33	Consensus	s1p5_off	Orthosteric Ligand	7YXA-S1P₅-ONO-5430608
8.33	Consensus	s1p_off	Orthosteric Ligand	s1p1_off s1p5_off
7.69	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
7.69	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
7.69	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
7.69	Single	5V56	TC114	5V56-SMO-TC114
7.69	Single	5V57	TC114	5V57-SMO-TC114
7.69	Single	6OS1	TRV026	6OS1-AT₁-TRV026
7.69	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
7.69	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/β1/γ2
7.69	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
7.69	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
7.69	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/β1/γ1
7.69	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/β1/γ1
7.69	Single	7R0C	AVP	7R0C-V₂-AVP-Arrestin2
7.69	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
7.69	Single	7T9N	DPPC	7T9N-TSH-M22 Fab-DPPC-Gs/β1/γ2
7.69	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/β1/γ2
7.69	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/β1/γ2
7.69	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/β1/γ2
7.69	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/β1/γ2
7.69	Single	8E0G	BU72	8E0G-μ-BU72
7.69	Single	8FMZ	Neurotensin/Neuromedin-N	8FMZ-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.69	Single	8FN1	Neurotensin/Neuromedin-N	8FN1-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi1-Go)/β1/γ2
7.69	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/β1/γ2
7.69	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
7.69	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
7.69	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
7.69	Single	8JBG	Neurokinin-B	8JBG-NK₃-Neurokinin-B-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	8JZP	C5A anaphylatoxin	8JZP-C5a₁-C5A anaphylatoxin-Go/β1/γ2
7.69	Single	8WJX	ADP	8WJX-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
7.69	Single	8XX7	CXCL5	8XX7-CXCR2-CXCL5-Go/β1/γ2
7.69	Single	9AST	Lymphotactin	9AST-XCR1-Lymphotactin-Gi1/β1/γ2
7.69	Single	9IZG	NKP	9IZG-LPA₁-NKP-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Consensus	class-a_off	Orthosteric Ligand	sensory_off alicarboxylic_off amine_off lipid_off nucleotide_off peptide_off protein_off
7.69	Consensus	gi_lpa	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
7.69	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
7.69	Consensus	lpa_on_gp	Orthosteric Ligand	lpa1_on_gp
7.69	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Consensus	neurotensin_on	Orthosteric Ligand	nts1_on
7.69	Consensus	nts1_on	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
7.69	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
7.69	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
7.69	Consensus	s1p5_on_gp	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
7.14	Single	4GRV	Neurotensin-(8-13)	4GRV-NTS₁-Neurotensin-(8-13)
7.14	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
7.14	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
7.14	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
7.14	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
7.14	Single	6OS2	TRV026	6OS2-AT₁-TRV026
7.14	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/β1/γ2
7.14	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/β1/γ2
7.14	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
7.14	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
7.14	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
7.14	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
7.14	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
7.14	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
7.14	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Single	8JPB	Neurotensin-(8-13)	8JPB-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
7.14	Single	8JPC	Neurotensin-(8-13)	8JPC-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
7.14	Single	8T3Q	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3Q-FFA4-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.14	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/β1/γ2
7.14	Single	8XQJ	JN241	8XQJ-Apelin-JN241
7.14	Single	8XWA	CXCL1	8XWA-CXCR2-CXCL1
7.14	Single	8XWM	CXCL6	8XWM-CXCR2-CXCL6
7.14	Single	8XWS	CXCL5	8XWS-CXCR2-CXCL5
7.14	Single	8XX3	CXCL3	8XX3-CXCR2-CXCL3-Go/β1/γ2
7.14	Single	9IZH	LPA	9IZH-LPA₁-LPA-chim(NtGi2-G13)/β1/γ2
7.14	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
7.14	Consensus	ccr8_on	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
7.14	Consensus	cxcr_on	Orthosteric Ligand	cxcr3_on cxcr4_on cxcr1_on cxcr2_on
7.14	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_ffa gi_leukotriene gi_lpa gi_s1p
7.14	Consensus	gi_neurotensin	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
7.14	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
7.14	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
7.14	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
7.14	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
7.14	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
7.14	Consensus	mop_on	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
7.14	Consensus	mop_on_gp	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
7.14	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Consensus	neurotensin_on_gp	Orthosteric Ligand	nts1_on_gp
7.14	Consensus	nts1_on_gp	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
7.14	Consensus	s1p1_on	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
7.14	Consensus	s1p1_on_gp	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
7.14	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
6.67	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
6.67	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
6.67	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
6.67	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
6.67	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
6.67	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
6.67	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
6.67	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
6.67	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
6.67	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/β1/γ2
6.67	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/β1/γ2
6.67	Single	8FN0	Neurotensin/Neuromedin-N	8FN0-NTS₁-Neurotensin/Neuromedin-N-SBI-553-chim(NtGi1-Go)/β1/γ2
6.67	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
6.67	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-SBI-553
6.67	Single	8K4O	CXCL1	8K4O-KSHV-CXCL1-Gi1/β1/γ1
6.67	Single	8XVU	CXCL2	8XVU-CXCR2-CXCL2
6.67	Single	8XWF	CXCL3	8XWF-CXCR2-CXCL3
6.67	Single	8XWV	CXCL1	8XWV-CXCR2-CXCL1-Go/β1/γ2
6.67	Single	8XXH	CXCL2	8XXH-CXCR2-CXCL2-Go/β1/γ2
6.67	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
6.67	Single	9C0K	Exendin-4	9C0K-GLP-1-Exendin-4-Gs/β1/γ2
6.67	Single	9GE3	Lysophosphatidylinositol	9GE3-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
6.67	Single	9IZF	NKP	9IZF-LPA₁-NKP-Gi1/β1/γ2
6.67	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
6.67	Consensus	gi_s1p	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7EW3-S1P₃-S1P-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EW1-S1P₅-Siponimod-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
6.67	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
6.25	Single	5VBL	Apelin mimetic peptide agonist	5VBL-Apelin-Apelin mimetic peptide agonist
6.25	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
6.25	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
6.25	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
6.25	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/β1/γ2
6.25	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/β1/γ2
6.25	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
6.25	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
6.25	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
6.25	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/β1/γ2
6.25	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
6.25	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
6.25	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs
6.25	Single	8XQJ	JN241	8XQJ-Apelin-JN241
6.25	Single	8XX6	CXCL8	8XX6-CXCR2-CXCL8-Go/β1/γ2
6.25	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
6.25	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II 3OE0-CXCR4-CVX15 3OE6-CXCR4-IT1t
6.25	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
6.25	Consensus	s1p_on	Orthosteric Ligand	s1p1_on s1p3_on s1p5_on
6.25	Consensus	s1p_on_gp	Orthosteric Ligand	s1p1_on_gp s1p3_on_gp s1p5_on_gp
5.88	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
5.88	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
5.88	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/β1/γ2
5.88	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/β1/γ1
5.88	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
5.88	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
5.88	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
5.88	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
5.88	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
5.88	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
5.88	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
5.88	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Gi1/β1/γ2
5.88	Single	8WZ2	Orexigenic Neuropeptide QRFP	8WZ2-QRFP-Orexigenic Neuropeptide QRFP-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.88	Single	8XFT	R-spondin-2	8XFT-LGR4-R-spondin-2-ZNRF3
5.88	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
5.88	Single	8XWN	CXCL8	8XWN-CXCR2-CXCL8
5.88	Single	8Y69	R-spondin-2	8Y69-LGR4-R-spondin-2-ZNRF3
5.88	Single	8YWF	Retatrutide	8YWF-GLP-1-Retatrutide-chim(NtGi1-Gs)/β1/γ2
5.88	Single	9BUE	Cagrilintide	9BUE-CT-Cagrilintide-Gs/β1/γ2
5.88	Single	9L3Y	Retinoic acid receptor responder protein 2	9L3Y-CML2-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
5.88	Consensus	ccr1_on	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
5.88	Consensus	ccr1_on_gp	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
5.88	Consensus	chemokine_on	Orthosteric Ligand	ccr_on cxcr_on
5.88	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
5.88	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
5.88	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
5.88	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
5.88	Consensus	lpl_on_gp	Orthosteric Ligand	s1p_on_gp lpa_on_gp
5.88	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
5.88	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
5.56	Single	6DO1	Angiotensin-like peptide S1I8	6DO1-AT₁-Angiotensin-like peptide S1I8
5.56	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
5.56	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
5.56	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
5.56	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
5.56	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/β1/γ2
5.56	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/β1/γ2
5.56	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
5.56	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
5.56	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
5.56	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
5.56	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
5.56	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/β1/γ2
5.56	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
5.56	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/β1/γ2
5.56	Single	8Z7J	Agonistic antibody	8Z7J-Apelin-Agonistic antibody-Gi1/β1/γ2
5.56	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
5.56	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
5.56	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
5.56	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
5.56	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
5.26	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
5.26	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
5.26	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
5.26	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/β1/γ2; RAMP2
5.26	Single	7O7F	6P4-CCL5	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1
5.26	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
5.26	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
5.26	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
5.26	Single	8K6N	Pro-neuropeptide-Y	8K6N-Y₂-Pro-neuropeptide-Y-Gi2/β1/γ1
5.26	Single	8WKZ	SBL-MC-31	8WKZ-MC₄-SBL-MC-31
5.26	Single	8WVU	R-spondin-1	8WVU-LGR4-R-spondin-1-RNF43
5.26	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/β1/γ2
5.26	Single	8Y69	R-spondin-2	8Y69-LGR4-R-spondin-2-ZNRF3
5.26	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
5.26	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
5.26	Single	9M1O	Morphine-Modulating Neuropeptide B	9M1O-NPFF2-Morphine-Modulating Neuropeptide B-Gi1/β1/γ2
5.26	Single	9U4W	Gonadoliberin-1	9U4W-GnRH₁-Gonadoliberin-1-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.26	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
5.26	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
5.26	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
5.26	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
5.26	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
5.26	Consensus	ccr_on	Orthosteric Ligand	ccr6_on ccr8_on ccr2_on ccr1_on ccr5_on
5.26	Consensus	class-b1_class-b2_cons_on	Orthosteric Ligand	class-b1_on class-b2_on
5.26	Consensus	class-b1_class-b2_cons_on_gp	Orthosteric Ligand	class-b1_on_gp class-b2_on_gp
5.26	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
5.26	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
5.26	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
5.26	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
5.00	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
5.00	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/β1/γ2
5.00	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
5.00	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
5.00	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
5.00	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
5.00	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
5.00	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
5.00	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
5.00	Single	7YON	Peptide-YY(3-36)	7YON-Y₂-Peptide-YY(3-36)-Gi1/β1/γ2
5.00	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
5.00	Single	8XFP	R-spondin-2	8XFP-LGR4-R-spondin-2-ZNRF3
5.00	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/β1/γ2
5.00	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
5.00	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ2
5.00	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
5.00	Single	9BLC	Cagrilintide backbone (non-acylated)	9BLC-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
5.00	Single	9BUD	Cagrilintide	9BUD-CT-Cagrilintide-Gs/β1/γ2
5.00	Single	9EBO	GLP-1 (ACPC18)	9EBO-GLP-1-GLP-1 (ACPC18)-Gs/β1/γ2
5.00	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
5.00	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
5.00	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
5.00	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
5.00	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
5.00	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
5.00	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
5.00	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
5.00	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
5.00	Consensus	protein_offon	Orthosteric Ligand	protein_off protein_on
5.00	Consensus	protein_offon_gp	Orthosteric Ligand	protein_on_gp protein_off
5.00	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
5.00	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
5.00	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
5.00	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
5.00	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
5.00	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
4.76	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
4.76	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
4.76	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
4.76	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
4.76	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
4.76	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/β1/γ2
4.76	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
4.76	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
4.76	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
4.76	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
4.76	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.76	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
4.76	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
4.76	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
4.76	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
4.76	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/β1/γ2
4.76	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
4.76	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/β1/γ2
4.76	Single	8XQE	Apelin-13	8XQE-Apelin-Apelin-13-Gi1/β1/γ2
4.76	Single	8XVH	Endothelin-1	8XVH-ET_B-Endothelin-1-chim(Gs-CtGq)/β1/γ2
4.76	Single	8XVI	Endothelin-1	8XVI-ET_A-Endothelin-1-chim(Gs-CtGq)/β1/γ2
4.76	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	9JFY	hNPSF	9JFY-NPFF2-hNPSF-Gi1/β1/γ2
4.76	Consensus	calcitonin_on	Orthosteric Ligand	ctlike_on
4.76	Consensus	ccr_on_gp	Orthosteric Ligand	ccr6_on_gp ccr8_on_gp ccr2_on_gp ccr1_on_gp ccr5_on_gp
4.76	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
4.76	Consensus	chemokine_on_gp	Orthosteric Ligand	ccr_on_gp cxcr_on_gp
4.76	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
4.76	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
4.76	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2 6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
4.76	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
4.76	Consensus	pac_on	Orthosteric Ligand	pac1_on
4.76	Consensus	vpac1_on	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
4.76	Consensus	vpac_on	Orthosteric Ligand	vpac1_on vpac2_on
4.55	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
4.55	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
4.55	Single	6FJ3	PTH	6FJ3-PTH1-PTH
4.55	Single	6NBF	Long-Acting PTH Analog	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
4.55	Single	6NBI	Long-Acting PTH Analog	6NBI-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
4.55	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
4.55	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
4.55	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
4.55	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
4.55	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
4.55	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ2
4.55	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
4.55	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
4.55	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
4.55	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
4.55	Single	9BLB	Cagrilintide backbone (non-acylated)	9BLB-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
4.55	Single	9BLW	Cagrilintide backbone (non-acylated)	9BLW-CT (AMY1)-Cagrilintide backbone (non-acylated)-Gs/β1/γ2; RAMP1
4.55	Single	9BP3	Cagrilintide	9BP3-CT (AMY1)-Cagrilintide-Gs/β1/γ2; RAMP1
4.55	Single	9BUB	Cagrilintide	9BUB-CT-Cagrilintide-Gs/β1/γ2
4.55	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
4.55	Consensus	calcitonin_on_gp	Orthosteric Ligand	ctlike_on_gp
4.55	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
4.55	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
4.55	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
4.55	Consensus	crf2_on_gp	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
4.55	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
4.55	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
4.55	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
4.55	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
4.55	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
4.55	Consensus	pac1_on	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
4.55	Consensus	pac1_on_gp	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
4.55	Consensus	pac_on_gp	Orthosteric Ligand	pac1_on_gp
4.55	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
4.55	Consensus	vpac1_on_gp	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
4.55	Consensus	vpac_on_gp	Orthosteric Ligand	vpac1_on_gp vpac2_on_gp
4.35	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
4.35	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
4.35	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
4.35	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
4.35	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
4.35	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
4.35	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
4.35	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2
4.35	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
4.35	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
4.35	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
4.35	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
4.35	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.35	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
4.35	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
4.35	Single	8XFS	R-spondin-2	8XFS-LGR4-R-spondin-2-ZNRF3
4.35	Single	8ZH8	QRF-Amide	8ZH8-QRFP-QRF-Amide-Gq/β1/γ1
4.35	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
4.35	Single	9BUC	Cagrilintide	9BUC-CT-Cagrilintide-Gs/β1/γ2
4.35	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
4.35	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
4.35	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
4.35	Consensus	glp2_on_gp	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
4.35	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
4.35	Consensus	glp_on_gp	Orthosteric Ligand	glp1_on_gp glp2_on_gp
4.35	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
4.35	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.35	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.35	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
4.35	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
4.17	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/β1/γ2
4.17	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
4.17	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
4.17	Single	6NBH	Long-Acting PTH Analog	6NBH-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
4.17	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
4.17	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
4.17	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
4.17	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
4.17	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
4.17	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
4.17	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
4.17	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
4.17	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
4.17	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
4.17	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
4.17	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
4.17	Single	9BQ3	Cagrilintide	9BQ3-CT (AMY2)-Cagrilintide-Gs/β1/γ2; RAMP2
4.17	Single	9BTW	Cagrilintide	9BTW-CT (AMY3)-Cagrilintide-Gs/β1/γ2; RAMP3
4.17	Single	9BYO	Exendin-3	9BYO-GLP-1-Exendin-3-Gs/β1/γ2
4.17	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
4.17	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
4.17	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
4.17	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
4.17	Consensus	ctlike_on_gp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
4.17	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
4.17	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
4.17	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
4.17	Consensus	pth1_on	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
4.17	Consensus	vip-pacap_on	Orthosteric Ligand	vpac_on pac_on
4.17	Consensus	vip-pacap_on_gp	Orthosteric Ligand	vpac_on_gp pac_on_gp
4.17	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
4.17	Consensus	vpac2_on_gp	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
4.00	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
4.00	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
4.00	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
4.00	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-LSN3556672-chim(NtGi1-Gs)/β1/γ2
4.00	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
4.00	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/β1/γ2
4.00	Consensus	ccr5_on_gp	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
4.00	Consensus	class-a_class-b1_cons_on	Orthosteric Ligand	class-a_on class-b1_on
4.00	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
4.00	Consensus	gip_on	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
4.00	Consensus	gip_on_gp	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
4.00	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
4.00	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
3.85	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/β1/γ1
3.85	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
3.85	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
3.85	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
3.85	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
3.85	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
3.85	Single	8FLU	Long-Acting PTH	8FLU-PTH1-Long-Acting PTH-Gs/β1/γ2
3.85	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT (AMY1)-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
3.85	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
3.85	Consensus	glp1_on	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
3.85	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
3.85	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
3.70	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
3.70	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
3.70	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
3.70	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
3.70	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
3.70	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
3.70	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
3.70	Consensus	crf_on_gp	Orthosteric Ligand	crf2_on_gp crf1_on_gp
3.70	Consensus	glp1_on_gp	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
3.70	Consensus	pth1_on_gp	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
3.57	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
3.57	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
3.57	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
3.57	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/β1/γ2
3.57	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
3.57	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
3.57	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
3.57	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
3.57	Consensus	class-a_class-b1_cons_on_gp	Orthosteric Ligand	class-a_on_gp class-b1_on_gp
3.57	Consensus	glucagon_on	Orthosteric Ligand	glp_on gluc_on secretin_on gip_on
3.57	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
3.45	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
3.45	Consensus	gluc_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
3.45	Consensus	glucagon_on_gp	Orthosteric Ligand	glp_on_gp gluc_on_gp secretin_on_gp gip_on_gp
3.45	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
3.33	Consensus	gluc_on_gp	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
3.33	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
3.33	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
3.23	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
3.23	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on vip-pacap_on pth_on crf_on calcitonin_on
3.23	Consensus	pth2_on_gp	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
3.12	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
3.03	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
3.03	Consensus	pth_on_gp	Orthosteric Ligand	pth1_on_gp pth2_on_gp
2.86	Consensus	class-b1_on_gp	Orthosteric Ligand	glucagon_on_gp vip-pacap_on_gp pth_on_gp crf_on_gp calcitonin_on_gp
2.78	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1

PDB Summary
PDB	8JD6
Class	C
SubFamily	Aminoacid
Type	Metabotropic Glutamate
SubType	mGlu4; mGlu4
Species	Homo Sapiens
Ligand	Phosphoserine
Other Ligand(s)	VU0364770
Protein Partners	Gi3/Beta1/Gamma2
PDB Resolution	3.4
Date	2023-06-21
D.O.I.	doi.org/10.1038/s41422-023-00830-2

Net Summary
I_min	3.52
Number of Linked Nodes	2012
Number of Links	2287
Number of Hubs	310
Number of Links mediated by Hubs	1158
Number of Communities	62
Number of Nodes involved in Communities	400
Number of Links involved in Communities	542

Path Summary
Number Of Nodes in MetaPath	198
Number Of Links MetaPath	197
Number of Shortest Paths	2976959
Length Of Smallest Path	3
Average Path Length	35.4058
Length of Longest Path	102
Minimum Path Strength	1.095
Average Path Strength	6.76477
Maximum Path Strength	25.35
Minimum Path Correlation	0.7
Average Path Correlation	0.998422
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.57143
Average % Of Corr. Nodes	73.4749
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	39.7542
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • GDP binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • cation binding • metal ion binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • cellular process • cell division • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • regulation of molecular function • regulation of adenylate cyclase activity
Gene Ontology	Biological Process	• cellular process • cell division • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • regulation of molecular function • regulation of adenylate cyclase activity • regulation of catalytic activity • negative regulation of molecular function • negative regulation of catalytic activity • negative regulation of adenylate cyclase activity • positive regulation of autophagy • catabolic process • macroautophagy • autophagy • positive regulation of biological process • regulation of catabolic process • regulation of autophagy • positive regulation of catabolic process • positive regulation of metabolic process • regulation of macroautophagy • metabolic process • positive regulation of macroautophagy • process utilizing autophagic mechanism • regulation of metabolic process • positive regulation of cellular process • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • nucleoside phosphate metabolic process • ribose phosphate metabolic process • purine nucleoside triphosphate metabolic process • GTP metabolic process • carbohydrate derivative metabolic process • primary metabolic process • nucleotide metabolic process • purine-containing compound metabolic process • nucleobase-containing compound metabolic process • purine nucleotide metabolic process • ribonucleotide metabolic process • organophosphate metabolic process • nucleobase-containing small molecule metabolic process • purine ribonucleoside triphosphate metabolic process • phosphate-containing compound metabolic process • small molecule metabolic process • nucleoside triphosphate metabolic process • purine ribonucleotide metabolic process • phosphorus metabolic process • midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle
Gene Ontology	Cellular Component	• midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytoplasm • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • glutamate receptor activity • G protein-coupled glutamate receptor activity • molecular transducer activity • adenylate cyclase inhibiting G protein-coupled glutamate receptor activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • positive regulation of cell communication • positive regulation of signal transduction • positive regulation of biological process • regulation of signal transduction • positive regulation of response to stimulus • regulation of intracellular signal transduction • positive regulation of cellular process • regulation of signaling • positive regulation of MAPK cascade • positive regulation of intracellular signal transduction • regulation of MAPK cascade • regulation of response to stimulus • MAPK cascade • regulation of cell communication • positive regulation of signaling • cell surface receptor signaling pathway • glutamate receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway • G protein-coupled glutamate receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • trans-synaptic signaling • anterograde trans-synaptic signaling • chemical synaptic transmission • cellular localization • neurotransmitter secretion • transport • secretion • export from cell • neurotransmitter transport • establishment of localization • localization • signal release from synapse • secretion by cell • signal release • establishment of localization in cell • neuron apoptotic process • regulation of apoptotic process • regulation of programmed cell death • cell death • apoptotic process • programmed cell death • regulation of neuron apoptotic process • modulation of chemical synaptic transmission • synaptic transmission, glutamatergic • regulation of synaptic transmission, glutamatergic • regulation of trans-synaptic signaling • cytoplasmic vesicle • intracellular vesicle • presynapse
SCOP2	Domain Identifier	• Ras-like P-loop GTPases
SCOP2	Family Identifier	• Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	SEP
PDB Residues	L:L:?1 M:M:?1
Environment Details	Open EMBL-EBI Page
Code	SEP
Name	Dexfosfoserine
Synonyms	PHOSPHONOSERINE
Identifier
Formula	C3 H8 N O6 P
Molecular Weight	185.072
SMILES
PubChem	68841
Formal Charge	0
Total Atoms	19
Total Chiral Atoms	1
Total Bonds	18
Total Aromatic Bonds	0


Code	BK0
PDB Residues	X:X:?1
Environment Details	Open EMBL-EBI Page
Code	BK0
Name	N-(3-chlorophenyl)pyridine-2-carboxamide
Synonyms
Identifier
Formula	C12 H9 Cl N2 O
Molecular Weight	232.666
SMILES
PubChem	836002
Formal Charge	0
Total Atoms	25
Total Chiral Atoms	0
Total Bonds	26
Total Aromatic Bonds	12


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P08754
Sequence	>8JD6_Chain_A S A E D K A A V E R S K M I D R N L R E D G E K A A K E V K L L L L G A G E S G K N T I V K Q M K I I G I V E T H F T D K D L Y F K M F D V G A Q R S E R K K W I H C F E G V T A I I F C V A L S D Y D L V L A E D E E M N R M H A S M K L F D S I C N N K W F T E T S I I L F L N K K D L F E E K I K R S P L T I C Y P E Y T G S N T Y E E A A A Y I Q C Q F E D L N R R K D T K E I Y T H F T C S T D T K N V Q F V F D A V T D V I I K N N L K E C G L Y Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>8JD6_Chain_B V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>8JD6_Chain_G K V S K A A A D L M A Y C E A H A K E Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q14833
Sequence	>8JD6_Chain_R N S I R I D G D I T L G G L F P V H G R G S E G K P C G E L K K E K G I H R L E A M L F A L D R I N N D P D L L P N I T L G A R I L D T C S R D T H A L E Q S L T F V Q A L I E R V V G V I G A S G S S V S I M V A N I L R L F K I P Q I S Y A S T A P D L S D N S R Y D F F S R V V P S D T Y Q A Q A M V D I V R A L K W N Y V S T V A S E G S Y G E S G V E A F I Q K S R E D G G V C I A Q S V K I P R E P K A G E F D K I I R R L L E T S N A R A V I I F A N E D D I R R V L E A A R R A N Q T G H F F W M G S D S W G S K I A P V L H L E E V A E G A V T I L P K R M S V R G F D R Y F S S R T L D N N R R N I W F A E F W E D N F H C K L V K K C T N R E R I G Q D S A Y E Q E G K V Q F V I D A V Y A M G H A L H A M H R D L C P G R V G L C P R M D P V D G T Q L L K Y I R N V N F S G I A G N P V T F N E N G D A P G R Y D I Y Q Y Q L R A E Y K V I G S W T D H L H L R I E R M H W L P R S I C S L P C Q P G E R K K T V K G M P C C W H C E P C T G Y Q Y Q V D R Y T C K T C P Y D M R P T E N R T G C R P I P I I K L E W G S P W A V L P L F L A V V G I A A T L F V V I T F V R Y N D T P I V K A S G R E L S Y V L L A G I F L C Y A T T F L M I A E P D L G T C S L R R I F L G L G M S I S Y A A L L T K T N R I Y R I F E Q G K R S V S A P R F I S P A S Q L A I T F S L I S L Q L L G I C V W F V V D P S H S V V D F Q D Q R T L D P R F A R G V L K C D I S D L S L I C L L G Y S M L L M V T C T V Y A I K T R G V P E T F N E A K P I G F T M Y T T C I V W L A F I P I F F G T S Q S A D K L Y I Q T T T L T V S V S L S A S V S L G M L Y M P K V Y I I L F H P E Q N V Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	S
Protein	Receptor
UniProt	Q14833
Sequence	>8JD6_Chain_S N S I R I D G D I T L G G L F P V H G R G S E G K P C G E L K K E K G I H R L E A M L F A L D R I N N D P D L L P N I T L G A R I L D T C S R D T H A L E Q S L T F V Q A L E R V V G V I G A S G S S V S I M V A N I L R L F K I P Q I S Y A S T A P D L S D N S R Y D F F S R V V P S D T Y Q A Q A M V D I V R A L K W N Y V S T V A S E G S Y G E S G V E A F I Q K S R E D G G V C I A Q S V K I P R E P K A G E F D K I I R R L L E T S N A R A V I I F A N E D D I R R V L E A A R R A N Q T G H F F W M G S D S W G S K I A P V L H L E E V A E G A V T I L P K R M S V R G F D R Y F S S R T L D N N R R N I W F A E F W E D N F H C K K K C T N R E R I G Q D S A Y E Q E G K V Q F V I D A V Y A M G H A L H A M H R D L C P G R V G L C P R M D P V D G T Q L L K Y I R N V N F S G I A G N P V T F N E N G D A P G R Y D I Y Q Y Q L R N D S A E Y K V I G S W T D H L H L R I E R M H W L P R S I C S L P C Q P G E R K K T V K G M P C C W H C E P C T G Y Q Y Q V D R Y T C K T C P Y D M R P T E N R T G C R P I P I I K L E W G S P W A V L P L F L A V V G I A A T L F V V I T F V R Y N D T P I V K A S G R E L S Y V L L A G I F L C Y A T T F L M I A E P D L G T C S L R R I F L G L G M S I S Y A A L L T K T N R I Y R I F E Q R F I S P A S Q L A I T F S L I S L Q L L G I C V W F V V D P S H S V V D F Q D Q R T L D P R F A R G V L K C D I S D L S L I C L L G Y S M L L M V T C T V Y A I K T R G V P E T F N E A K P I G F T M Y T T C I V W L A F I P I F F G T S Q S A D K L Y I Q T T T L T V S V S L S A S V S L G M L Y M P K V Y I I L F H Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8JD6	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu4	Homo sapiens	Phosphoserine	VU0364770	Gi3/β1/γ2	3.4	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	8JD6 (No Gprot)	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu4	Homo sapiens	Phosphoserine	VU0364770		3.4	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	8WGB	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	Glutammate	VU0155041	Gi3/β1/γ2	3.7	2024-10-30	doi.org/10.1038/s41467-024-54744-7
	8WGB (No Gprot)	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	Glutammate	VU0155041		3.7	2024-10-30	doi.org/10.1038/s41467-024-54744-7
	8JD5	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu4	Homo sapiens	Glutamate	JNJ-40411813; ADX88178	Gi1/β1/γ2	3.6	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	8JD5 (No Gprot)	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu4	Homo sapiens	Glutamate	JNJ-40411813; ADX88178		3.6	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	8JD4	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu4	Homo sapiens	Glutamate	-	-	2.9	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	8WG9	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	(2S)-2-amino-4-phosphonobutanoic acid	-	-	4.46	2024-11-27	doi.org/10.1038/s41467-024-54744-7
	8WGC	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	LY379268	-	-	5.95	2024-11-27	doi.org/10.1038/s41467-024-54744-7
	8WGD	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	WAG; WA6	-	-	4.45	2024-11-27	doi.org/10.1038/s41467-024-54744-7
	7E9H	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu4	Homo sapiens	Phosphoserine	-	Gi3/β1/γ2	4	2021-06-23	doi.org/10.1038/s41586-021-03495-2
	7E9H (No Gprot)	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu4	Homo sapiens	Phosphoserine	-		4	2021-06-23	doi.org/10.1038/s41586-021-03495-2

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8JD6.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.