psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:L12	A:A:T11	4.42	No	No	0	2	4
2	A:A:D16	A:A:L12	8.14	No	No	0	4	2
3	A:A:K17	A:A:L12	2.82	No	No	0	3	2
4	A:A:D16	A:A:S13	5.89	No	No	0	4	7
5	A:A:K24	A:A:V20	3.04	No	No	0	4	3
6	A:A:V20	B:B:N88	2.96	No	Yes	0	3	7
7	A:A:R22	B:B:H91	3.39	No	Yes	0	5	5
8	A:A:S23	B:B:N88	4.47	No	Yes	0	7	7
9	A:A:K28	A:A:M25	4.32	No	No	0	4	4
10	A:A:I26	A:A:L30	2.85	No	No	5	9	5
11	A:A:I26	B:B:K89	5.82	No	Yes	5	9	9
12	A:A:E27	B:B:K89	8.1	No	Yes	0	6	9
13	A:A:K32	A:A:Q29	4.07	No	No	0	4	4
14	A:A:D33	A:A:Q29	6.53	No	No	0	5	4
15	A:A:L30	B:B:K89	2.82	No	Yes	5	5	9
16	A:A:K34	A:A:Q31	4.07	Yes	No	0	4	4
17	A:A:D33	B:B:K78	5.53	No	No	0	5	8
18	A:A:K34	B:B:L55	5.64	Yes	No	0	4	6
19	A:A:K34	R:R:Q61	5.42	Yes	No	20	4	6
20	A:A:K34	R:R:Q64	2.71	Yes	No	20	4	8
21	A:A:Q35	R:R:T144	2.83	No	No	0	3	9
22	A:A:R42	A:A:Y37	12.35	No	No	0	9	4
23	A:A:Y37	B:B:L55	3.52	No	No	0	4	6
24	A:A:R38	R:R:Q64	21.03	No	No	0	4	8
25	A:A:R38	R:R:P140	2.88	No	No	0	4	7
26	A:A:R42	A:A:T40	3.88	No	No	0	9	7
27	A:A:H220	A:A:T40	6.85	No	No	0	7	7
28	A:A:H41	A:A:V217	2.77	Yes	No	22	6	5
29	A:A:F219	A:A:H41	4.53	Yes	Yes	22	8	6
30	A:A:H41	A:A:T242	4.11	Yes	No	0	6	8
31	A:A:H41	R:R:L137	5.14	Yes	No	0	6	7
32	A:A:F222	A:A:R42	3.21	No	No	0	7	9
33	A:A:F219	A:A:L43	4.87	Yes	No	0	8	7
34	A:A:I245	A:A:L43	2.85	No	No	0	7	7
35	A:A:L44	A:A:L46	5.54	No	Yes	23	9	8
36	A:A:F238	A:A:L44	10.96	Yes	No	0	9	9
37	A:A:I244	A:A:L44	4.28	No	No	23	8	9
38	A:A:K53	A:A:L45	5.64	No	No	0	9	8
39	A:A:D223	A:A:L45	4.07	No	No	0	9	8
40	A:A:I245	A:A:L45	2.85	No	No	0	7	8
41	A:A:I244	A:A:L46	2.85	No	Yes	23	8	8
42	A:A:F246	A:A:L46	3.65	No	Yes	0	9	8
43	A:A:D249	A:A:N50	9.42	No	No	0	9	9
44	A:A:D252	A:A:N50	4.04	No	No	24	8	9
45	A:A:N50	A:A:R265	9.64	No	Yes	24	9	9
46	A:A:S51	A:A:V247	6.46	No	No	0	9	7
47	A:A:K58	A:A:S54	3.06	No	No	0	9	9
48	A:A:S366	A:A:T55	7.99	No	No	0	9	9
49	A:A:I56	A:A:N292	4.25	No	Yes	0	7	9
50	A:A:R61	A:A:V57	3.92	No	No	0	8	7
51	A:A:M60	A:A:Q59	8.16	No	No	0	9	9
52	A:A:N371	A:A:Q59	3.96	Yes	No	0	9	9
53	A:A:F212	A:A:M60	4.98	Yes	No	0	9	9
54	A:A:F208	A:A:S205	3.96	No	No	0	5	7
55	A:A:G206	B:B:N119	5.09	No	Yes	0	8	9
56	A:A:I207	A:A:V224	3.07	No	No	0	9	9
57	A:A:I207	B:B:W99	3.52	No	Yes	0	9	9
58	A:A:D223	A:A:F208	4.78	No	No	0	9	5
59	A:A:F208	A:A:G225	4.52	No	No	0	5	9
60	A:A:E209	A:A:K211	12.15	No	No	21	9	4
61	A:A:E209	A:A:H220	9.85	No	No	21	9	7
62	A:A:E209	A:A:F222	11.66	No	No	0	9	7
63	A:A:M221	A:A:T210	3.01	No	No	0	8	7
64	A:A:H220	A:A:K211	14.41	No	No	21	7	4
65	A:A:F212	A:A:F219	10.72	Yes	Yes	0	9	8
66	A:A:F212	A:A:M221	3.73	Yes	No	0	9	8
67	A:A:A372	A:A:F212	2.77	No	Yes	0	8	9
68	A:A:N218	A:A:Q213	7.92	No	No	0	4	3
69	A:A:D215	A:A:V214	2.92	No	No	14	5	6
70	A:A:R373	A:A:V214	3.92	No	No	14	5	6
71	A:A:F376	A:A:V214	5.24	No	No	14	8	6
72	A:A:D215	A:A:R373	10.72	No	No	14	5	5
73	A:A:D215	A:A:F376	4.78	No	No	14	5	8
74	A:A:F219	A:A:V217	5.24	Yes	No	22	8	5
75	A:A:C379	A:A:F219	2.79	No	Yes	0	8	8
76	A:A:I245	A:A:M221	2.92	No	No	0	7	8
77	A:A:F222	B:B:W99	10.02	No	Yes	0	7	9
78	A:A:Q227	A:A:V224	2.87	Yes	No	0	9	9
79	A:A:V224	A:A:W234	7.36	No	Yes	0	9	9
80	A:A:Q227	B:B:L117	3.99	Yes	No	4	9	9
81	A:A:Q227	B:B:N119	3.96	Yes	Yes	0	9	9
82	A:A:Q227	B:B:Y145	4.51	Yes	Yes	4	9	8
83	A:A:E230	A:A:R228	9.3	No	No	0	9	9
84	A:A:R228	B:B:T164	5.17	No	No	0	9	6
85	A:A:R231	A:A:W234	6	No	Yes	0	9	9
86	A:A:D272	A:A:R231	10.72	No	No	0	8	9
87	A:A:K233	B:B:D186	4.15	Yes	Yes	4	9	9
88	A:A:K233	B:B:M188	4.32	Yes	No	4	9	8
89	A:A:K233	B:B:C204	4.85	Yes	Yes	4	9	7
90	A:A:K233	B:B:D228	5.53	Yes	Yes	4	9	9
91	A:A:I235	A:A:W234	3.52	No	Yes	0	9	9
92	A:A:F238	A:A:W234	3.01	Yes	Yes	0	9	9
93	A:A:W234	B:B:Y145	4.82	Yes	Yes	0	9	8
94	A:A:Q236	A:A:W281	8.76	No	Yes	0	8	5
95	A:A:C237	A:A:F238	2.79	No	Yes	0	8	9
96	A:A:C237	B:B:Y59	2.69	No	Yes	2	8	8
97	A:A:C237	B:B:Q75	6.1	No	Yes	2	8	9
98	A:A:F238	A:A:V241	3.93	Yes	No	0	9	9
99	A:A:F238	B:B:W99	9.02	Yes	Yes	0	9	9
100	A:A:D240	A:A:N239	5.39	No	No	2	6	8
101	A:A:N239	B:B:K57	5.6	No	Yes	2	8	9
102	A:A:N239	B:B:W332	4.52	No	Yes	2	8	9
103	A:A:D240	B:B:K57	5.53	No	Yes	2	6	9
104	A:A:I285	A:A:V241	3.07	No	No	0	7	9
105	A:A:I244	A:A:I285	2.94	No	No	0	8	7
106	A:A:D272	A:A:F246	8.36	No	No	0	8	9
107	A:A:F246	A:A:L289	3.65	No	No	0	9	9
108	A:A:N292	A:A:V247	2.96	Yes	No	0	9	7
109	A:A:F345	A:A:V248	6.55	Yes	No	0	8	7
110	A:A:D249	A:A:S251	7.36	No	No	0	9	9
111	A:A:D249	A:A:K293	17.97	No	No	0	9	9
112	A:A:D252	A:A:S251	2.94	No	No	0	8	9
113	A:A:D252	A:A:R265	5.96	No	Yes	24	8	9
114	A:A:K300	A:A:Y253	15.53	No	No	0	9	8
115	A:A:I308	A:A:Y253	13.3	No	No	0	7	8
116	A:A:Y253	A:A:Y311	7.94	No	No	0	8	6
117	A:A:E268	A:A:R265	6.98	No	Yes	0	9	9
118	A:A:F312	A:A:L266	3.65	No	No	0	8	8
119	A:A:I341	A:A:L266	2.85	No	No	0	8	8
120	A:A:L270	A:A:Q267	5.32	Yes	No	0	6	4
121	A:A:N271	A:A:Q267	5.28	No	No	0	5	4
122	A:A:E344	A:A:L270	3.98	No	Yes	0	5	6
123	A:A:F345	A:A:L270	9.74	Yes	Yes	0	8	6
124	A:A:I348	A:A:L270	2.85	No	Yes	0	4	6
125	A:A:F273	A:A:F345	5.36	No	Yes	0	9	8
126	A:A:F273	A:A:I348	6.28	No	No	0	9	4
127	A:A:C359	A:A:F273	2.79	No	No	0	5	9
128	A:A:K274	A:A:N278	4.2	No	No	0	5	8
129	A:A:I348	A:A:K274	4.36	No	No	0	4	5
130	A:A:N278	A:A:W277	5.65	No	Yes	25	8	6
131	A:A:V287	A:A:W277	3.68	No	Yes	0	6	6
132	A:A:S349	A:A:W277	3.71	No	Yes	0	7	6
133	A:A:S352	A:A:W277	4.94	No	Yes	25	5	6
134	A:A:H357	A:A:W277	20.1	No	Yes	0	7	6
135	A:A:N278	A:A:S352	5.96	No	No	25	8	5
136	A:A:L282	A:A:N279	10.98	No	No	0	9	8
137	A:A:R280	A:A:W281	16.99	No	Yes	0	5	5
138	A:A:R280	A:A:R283	5.33	No	No	0	5	3
139	A:A:W281	B:B:D290	4.47	Yes	Yes	2	5	6
140	A:A:W281	B:B:R314	9	Yes	Yes	2	5	8
141	A:A:R283	A:A:R356	6.4	No	No	0	3	2
142	A:A:R356	A:A:T284	7.76	No	No	0	2	4
143	A:A:I382	A:A:S286	7.74	No	No	0	6	8
144	A:A:D378	A:A:I288	11.2	Yes	No	0	7	9
145	A:A:L289	A:A:L291	2.77	No	No	0	9	8
146	A:A:F345	A:A:L289	4.87	Yes	No	0	8	9
147	A:A:F290	A:A:H362	5.66	No	No	0	9	9
148	A:A:F290	A:A:T364	11.67	No	Yes	0	9	9
149	A:A:F363	A:A:L291	3.65	Yes	No	0	5	8
150	A:A:K293	A:A:N292	4.2	No	Yes	0	9	9
151	A:A:N292	A:A:T364	4.39	Yes	Yes	0	9	9
152	A:A:N292	A:A:S366	7.45	Yes	No	0	9	9
153	A:A:K338	A:A:Q294	2.71	No	No	26	5	6
154	A:A:F363	A:A:Q294	9.37	Yes	No	26	5	6
155	A:A:D295	A:A:L296	2.71	No	No	0	9	6
156	A:A:D295	A:A:E299	3.9	No	No	0	9	6
157	A:A:L297	A:A:V334	2.98	No	Yes	0	8	4
158	A:A:K300	A:A:S306	9.18	No	No	0	9	7
159	A:A:D331	A:A:L302	5.43	Yes	No	0	4	2
160	A:A:K305	A:A:S306	3.06	No	No	0	3	7
161	A:A:E309	A:A:K307	9.45	No	No	0	4	6
162	A:A:F315	A:A:I308	7.54	No	No	0	6	7
163	A:A:D310	A:A:Y311	6.9	No	No	0	3	6
164	A:A:E314	A:A:P313	6.29	No	No	0	6	6
165	A:A:E314	A:A:R317	5.82	No	No	0	6	2
166	A:A:F315	A:A:R336	12.83	No	No	0	6	5
167	A:A:F315	A:A:F340	13.93	No	No	0	6	7
168	A:A:P321	A:A:Y318	5.56	No	No	0	5	6
169	A:A:F340	A:A:Y318	5.16	No	No	0	7	6
170	A:A:D343	A:A:Y318	9.2	No	No	0	3	6
171	A:A:P321	A:A:T320	3.5	No	No	0	5	1
172	A:A:R336	A:A:T320	3.88	No	No	0	5	1
173	A:A:A324	A:A:Y339	6.67	No	Yes	0	3	3
174	A:A:P326	A:A:T335	8.74	No	No	0	1	4
175	A:A:E327	A:A:P328	14.15	No	No	0	4	1
176	A:A:D331	A:A:P332	3.22	Yes	No	0	4	1
177	A:A:D331	A:A:R333	10.72	Yes	No	0	4	5
178	A:A:K338	A:A:Y339	3.58	No	Yes	0	5	3
179	A:A:F363	A:A:K338	12.41	Yes	No	26	5	5
180	A:A:R342	A:A:Y339	7.2	Yes	Yes	0	4	3
181	A:A:E344	A:A:F340	4.66	No	No	0	5	7
182	A:A:P361	A:A:R342	5.76	No	Yes	0	5	4
183	A:A:F363	A:A:R342	3.21	Yes	Yes	0	5	4
184	A:A:D343	A:A:R347	3.57	No	No	0	3	4
185	A:A:E344	A:A:R347	10.47	No	No	0	5	4
186	A:A:S349	A:A:T350	3.2	No	No	0	7	4
187	A:A:C359	A:A:S349	3.44	No	No	0	5	7
188	A:A:G355	A:A:Y358	2.9	No	Yes	0	2	4
189	A:A:Y358	A:A:Y360	2.98	Yes	Yes	15	4	8
190	A:A:R385	A:A:Y358	9.26	Yes	Yes	15	5	4
191	A:A:R389	A:A:Y358	3.09	No	Yes	0	4	4
192	A:A:Y358	R:R:L226	5.86	Yes	Yes	15	4	5
193	A:A:D378	A:A:Y360	8.05	Yes	Yes	0	7	8
194	A:A:I382	A:A:Y360	4.84	No	Yes	0	6	8
195	A:A:R385	A:A:Y360	6.17	Yes	Yes	15	5	8
196	A:A:H362	A:A:R374	6.77	No	Yes	0	9	4
197	A:A:D378	A:A:H362	8.82	Yes	No	0	7	9
198	A:A:N371	A:A:T364	2.92	Yes	Yes	13	9	9
199	A:A:R374	A:A:T364	6.47	Yes	Yes	13	4	9
200	A:A:C365	A:A:D368	7.78	No	No	0	8	9
201	A:A:D368	A:A:N371	4.04	No	Yes	13	9	9
202	A:A:D368	A:A:R374	4.76	No	Yes	13	9	4
203	A:A:E370	A:A:R373	6.98	No	No	0	4	5
204	A:A:N371	A:A:R374	3.62	Yes	Yes	13	9	4
205	A:A:F376	R:R:L137	4.87	No	No	0	8	7
206	A:A:Q384	A:A:R380	3.5	Yes	No	27	6	7
207	A:A:R380	R:R:P136	7.21	No	No	27	7	9
208	A:A:I383	R:R:P136	3.39	No	No	0	8	9
209	A:A:Q384	R:R:P136	4.74	Yes	No	27	6	9
210	A:A:Q384	R:R:Q222	5.12	Yes	No	0	6	8
211	A:A:R385	R:R:Q222	11.68	Yes	No	0	5	8
212	A:A:R385	R:R:L226	6.07	Yes	Yes	15	5	5
213	A:A:L388	A:A:L393	2.77	No	Yes	0	8	8
214	A:A:L388	R:R:I133	4.28	No	No	0	8	8
215	A:A:L394	A:A:R389	4.86	No	No	0	8	4
216	A:A:Q390	R:R:K459	5.42	No	No	0	4	5
217	A:A:Q390	R:R:T460	4.25	No	No	0	4	8
218	A:A:Y391	R:R:R129	12.35	No	Yes	0	4	9
219	A:A:Y391	R:R:H458	7.62	No	Yes	0	4	9
220	A:A:E392	R:R:M457	2.71	No	No	0	6	8
221	A:A:E392	R:R:K462	4.05	No	No	0	6	8
222	A:A:L393	R:R:V215	2.98	Yes	No	0	8	9
223	A:A:L393	R:R:A397	3.15	Yes	No	0	8	8
224	A:A:L393	R:R:I401	2.85	Yes	No	0	8	9
225	A:A:L394	R:R:L226	4.15	No	Yes	0	8	5
226	B:B:L7	B:B:Q6	6.65	Yes	No	0	8	1
227	B:B:L7	G:G:A12	3.15	Yes	No	0	8	5
228	B:B:Q9	B:B:R8	4.67	No	No	0	3	3
229	B:B:E10	G:G:K20	2.7	No	No	0	8	6
230	B:B:L14	G:G:L19	2.77	No	Yes	0	8	9
231	B:B:L14	G:G:K20	8.46	No	No	0	8	6
232	B:B:K15	G:G:L19	2.82	No	Yes	0	6	9
233	B:B:N16	B:B:R19	13.26	No	No	0	1	4
234	B:B:I18	B:B:R22	5.01	No	No	0	7	6
235	B:B:I18	G:G:A23	3.25	No	No	0	7	8
236	B:B:A21	G:G:R27	2.77	No	Yes	0	4	8
237	B:B:D258	B:B:R22	7.15	Yes	No	0	7	6
238	B:B:R22	G:G:R27	3.2	No	Yes	0	6	8
239	B:B:A26	B:B:Q259	4.55	No	No	0	3	6
240	B:B:A28	B:B:D27	3.09	No	No	0	4	8
241	B:B:D27	G:G:K29	11.06	No	No	0	8	4
242	B:B:D27	G:G:S31	8.83	No	No	0	8	9
243	B:B:Q32	B:B:T29	9.92	No	No	0	1	3
244	B:B:L30	B:B:T34	4.42	Yes	No	0	5	5
245	B:B:L261	B:B:L30	4.15	No	Yes	0	5	5
246	B:B:L30	B:B:M262	4.24	Yes	Yes	0	5	4
247	B:B:L30	G:G:A34	4.73	Yes	No	0	5	6
248	B:B:M262	B:B:S31	3.07	Yes	No	0	4	1
249	B:B:I37	B:B:T34	3.04	No	No	0	2	5
250	B:B:L300	B:B:T34	4.42	Yes	No	0	6	5
251	B:B:N35	B:B:N36	2.72	No	No	0	1	1
252	B:B:I37	G:G:M38	2.92	No	No	0	2	4
253	B:B:D38	B:B:P39	4.83	No	No	0	1	1
254	B:B:R283	B:B:V40	7.85	No	Yes	16	9	3
255	B:B:D298	B:B:V40	7.3	Yes	Yes	16	9	3
256	B:B:V40	G:G:L51	2.98	Yes	Yes	0	3	6
257	B:B:I43	B:B:M45	2.92	No	No	0	3	4
258	B:B:M45	B:B:W339	3.49	No	Yes	0	4	9
259	B:B:M45	G:G:L50	2.83	No	No	0	4	9
260	B:B:R46	B:B:R48	7.46	No	No	0	5	7
261	B:B:T47	B:B:W339	7.28	No	Yes	0	3	9
262	B:B:N340	B:B:R48	9.64	No	No	0	9	7
263	B:B:I338	B:B:R49	5.01	No	No	0	5	7
264	B:B:R52	B:B:T50	3.88	No	No	0	7	3
265	B:B:K337	B:B:T50	4.5	Yes	No	0	6	3
266	B:B:L51	B:B:W82	9.11	No	Yes	5	9	9
267	B:B:L336	B:B:L51	5.54	Yes	No	5	7	9
268	B:B:F335	B:B:R52	8.55	No	No	0	4	7
269	B:B:H54	B:B:I58	5.3	Yes	No	0	9	9
270	B:B:H54	B:B:S72	6.97	Yes	No	5	9	9
271	B:B:H54	B:B:S74	12.55	Yes	No	0	9	9
272	B:B:H54	B:B:I80	10.61	Yes	No	5	9	8
273	B:B:H54	B:B:W82	3.17	Yes	Yes	5	9	9
274	B:B:D76	B:B:L55	14.93	Yes	No	0	9	6
275	B:B:K57	B:B:Y59	4.78	Yes	Yes	2	9	8
276	B:B:K57	B:B:Q75	6.78	Yes	Yes	2	9	9
277	B:B:K57	B:B:W332	13.92	Yes	Yes	2	9	9
278	B:B:I58	B:B:L336	2.85	No	Yes	0	9	7
279	B:B:Q75	B:B:Y59	11.27	Yes	Yes	2	9	8
280	B:B:M101	B:B:Y59	3.59	No	Yes	0	9	8
281	B:B:W332	B:B:Y59	3.86	Yes	Yes	2	9	8
282	B:B:C317	B:B:M61	4.86	No	No	0	7	6
283	B:B:A328	B:B:M61	3.22	No	No	0	5	6
284	B:B:H62	B:B:R150	12.41	No	No	0	6	6
285	B:B:L70	B:B:W63	6.83	No	Yes	0	5	7
286	B:B:S84	B:B:W63	6.18	No	Yes	0	5	7
287	B:B:T321	B:B:W63	3.64	No	Yes	0	7	7
288	B:B:A328	B:B:W63	3.89	No	Yes	0	5	7
289	B:B:G64	B:B:Y105	4.35	No	Yes	0	5	6
290	B:B:D66	B:B:R68	3.57	No	No	0	8	5
291	B:B:D66	B:B:L69	5.43	No	No	0	8	5
292	B:B:S67	B:B:T321	4.8	No	No	30	5	7
293	B:B:D323	B:B:S67	4.42	No	No	30	7	5
294	B:B:D83	B:B:R68	14.29	No	No	0	8	5
295	B:B:R68	B:B:Y85	21.61	No	No	0	5	4
296	B:B:D83	B:B:L69	4.07	No	No	0	8	5
297	B:B:L70	B:B:W82	4.56	No	Yes	0	5	9
298	B:B:I81	B:B:V71	3.07	No	No	0	7	8
299	B:B:S72	B:B:W82	6.18	No	Yes	5	9	9
300	B:B:L336	B:B:S72	3	Yes	No	5	7	9
301	B:B:A73	B:B:V100	3.39	No	No	0	9	9
302	B:B:A73	B:B:C103	3.61	No	No	0	9	8
303	B:B:D76	B:B:S74	7.36	Yes	No	0	9	9
304	B:B:Q75	B:B:W99	5.48	Yes	Yes	0	9	9
305	B:B:D76	B:B:G77	3.35	Yes	No	0	9	8
306	B:B:D76	B:B:K78	6.91	Yes	No	0	9	8
307	B:B:K78	B:B:P94	3.35	No	No	0	8	5
308	B:B:I93	B:B:L79	4.28	No	No	0	7	7
309	B:B:L79	B:B:L95	2.77	No	Yes	17	7	8
310	B:B:C114	B:B:L79	3.17	No	No	17	8	7
311	B:B:I80	B:B:W82	15.27	No	Yes	5	8	9
312	B:B:H91	B:B:I81	5.3	Yes	No	0	5	7
313	B:B:I81	B:B:L126	2.85	No	No	0	7	5
314	B:B:K89	B:B:W82	9.28	Yes	Yes	5	9	9
315	B:B:L336	B:B:W82	3.42	Yes	Yes	5	7	9
316	B:B:D83	B:B:T86	7.23	No	No	0	8	6
317	B:B:I338	B:B:S84	3.1	No	No	0	5	5
318	B:B:S84	G:G:F61	3.96	No	Yes	0	5	8
319	B:B:Y85	G:G:P60	12.52	No	No	31	4	9
320	B:B:Y85	G:G:F61	6.19	No	Yes	31	4	8
321	B:B:N88	B:B:T86	7.31	Yes	No	0	7	6
322	B:B:H91	B:B:V90	5.54	Yes	No	0	5	5
323	B:B:H91	B:B:V133	5.54	Yes	No	0	5	4
324	B:B:I93	B:B:P94	3.39	No	No	0	7	5
325	B:B:I93	B:B:V133	4.61	No	No	0	7	4
326	B:B:L95	B:B:V100	4.47	Yes	No	0	8	9
327	B:B:C114	B:B:L95	3.17	No	Yes	17	8	8
328	B:B:L95	B:B:Y124	5.86	Yes	Yes	17	8	6
329	B:B:E138	B:B:R96	4.65	No	No	0	6	6
330	B:B:D118	B:B:S97	8.83	No	No	0	9	8
331	B:B:L117	B:B:W99	5.69	No	Yes	0	9	9
332	B:B:G116	B:B:M101	3.49	No	No	0	9	9
333	B:B:M101	B:B:Y145	3.59	No	Yes	0	9	8
334	B:B:C149	B:B:T102	3.38	No	No	0	8	8
335	B:B:G109	B:B:Y105	4.35	No	Yes	0	5	6
336	B:B:F151	B:B:P107	2.89	No	No	0	9	6
337	B:B:N110	B:B:S108	7.45	No	No	32	4	6
338	B:B:D154	B:B:S108	4.42	No	No	32	6	6
339	B:B:K127	B:B:N110	9.79	No	No	0	4	4
340	B:B:D154	B:B:N110	4.04	No	No	32	6	4
341	B:B:I123	B:B:Y111	3.63	Yes	No	0	6	4
342	B:B:N125	B:B:Y111	12.79	No	No	0	4	4
343	B:B:D154	B:B:Y111	9.2	No	No	0	6	4
344	B:B:L126	B:B:V112	2.98	No	No	0	5	8
345	B:B:C114	B:B:Y124	5.38	No	Yes	17	8	6
346	B:B:L117	B:B:Y145	3.52	No	Yes	4	9	8
347	B:B:D118	B:B:I120	8.4	No	No	0	9	6
348	B:B:G144	B:B:N119	5.09	No	Yes	0	8	9
349	B:B:E138	B:B:I120	5.47	No	No	0	6	6
350	B:B:C121	B:B:L139	3.17	No	Yes	0	8	9
351	B:B:S122	B:B:Y124	5.09	No	Yes	0	8	6
352	B:B:E138	B:B:S122	4.31	No	No	0	6	8
353	B:B:I123	B:B:S136	3.1	Yes	No	0	6	4
354	B:B:I123	B:B:R137	3.76	Yes	No	33	6	5
355	B:B:I123	B:B:L139	4.28	Yes	Yes	0	6	9
356	B:B:I123	B:B:I171	4.42	Yes	No	33	6	6
357	B:B:V135	B:B:Y124	5.05	No	Yes	0	4	6
358	B:B:N125	B:B:T128	5.85	No	Yes	0	4	3
359	B:B:L126	B:B:V133	2.98	No	No	0	5	4
360	B:B:E130	B:B:T128	4.23	No	Yes	18	3	3
361	B:B:N132	B:B:T128	2.92	No	Yes	18	3	3
362	B:B:R134	B:B:T128	6.47	No	Yes	18	3	3
363	B:B:E130	B:B:N132	5.26	No	No	18	3	3
364	B:B:E130	B:B:R134	6.98	No	No	18	3	3
365	B:B:I171	B:B:R137	3.76	No	No	33	6	5
366	B:B:L139	B:B:W169	11.39	Yes	Yes	0	9	8
367	B:B:H142	B:B:L146	5.14	Yes	No	6	9	7
368	B:B:H142	B:B:T159	5.48	Yes	No	6	9	9
369	B:B:H142	B:B:S161	13.95	Yes	No	6	9	9
370	B:B:D163	B:B:H142	5.04	Yes	Yes	6	9	9
371	B:B:H142	B:B:T165	2.74	Yes	No	6	9	7
372	B:B:A167	B:B:H142	2.93	No	Yes	6	4	9
373	B:B:H142	B:B:W169	4.23	Yes	Yes	6	9	8
374	B:B:D163	B:B:T143	5.78	Yes	No	0	9	5
375	B:B:G162	B:B:Y145	5.79	No	Yes	0	9	8
376	B:B:D186	B:B:Y145	6.9	Yes	Yes	4	9	8
377	B:B:L146	B:B:T159	4.42	No	No	6	7	9
378	B:B:S147	B:B:S160	3.26	No	No	0	9	6
379	B:B:C148	B:B:R150	2.79	No	No	0	6	6
380	B:B:C148	B:B:L190	3.17	No	No	0	6	5
381	B:B:F151	B:B:I171	3.77	No	No	0	9	6
382	B:B:D153	B:B:L152	6.79	No	No	0	5	3
383	B:B:L152	B:B:L192	4.15	No	No	0	3	5
384	B:B:L152	B:B:T196	4.42	No	No	0	3	1
385	B:B:D153	B:B:Q156	13.05	No	No	0	5	5
386	B:B:D170	B:B:N155	4.04	No	No	0	9	3
387	B:B:E172	B:B:N155	5.26	No	No	0	6	3
388	B:B:I157	B:B:W169	3.52	No	Yes	0	7	8
389	B:B:L190	B:B:V158	2.98	No	No	3	5	5
390	B:B:F199	B:B:V158	3.93	Yes	No	3	9	5
391	B:B:T159	B:B:W169	8.49	No	Yes	6	9	8
392	B:B:S160	B:B:V187	6.46	No	No	0	6	9
393	B:B:G162	B:B:S161	3.71	No	No	0	9	9
394	B:B:D163	B:B:S161	8.83	Yes	No	6	9	9
395	B:B:D163	B:B:T165	11.56	Yes	No	6	9	7
396	B:B:T165	B:B:T181	3.14	No	No	0	7	2
397	B:B:C166	B:B:F180	4.19	No	Yes	0	8	7
398	B:B:A167	B:B:W169	3.89	No	Yes	6	4	8
399	B:B:A167	B:B:Q176	4.55	No	No	6	4	4
400	B:B:L168	B:B:T177	4.42	No	No	3	6	4
401	B:B:L168	B:B:T178	5.9	No	No	3	6	4
402	B:B:Q176	B:B:W169	12.05	No	Yes	6	4	8
403	B:B:D170	B:B:T173	5.78	No	No	0	9	5
404	B:B:D170	B:B:T177	4.34	No	No	0	9	4
405	B:B:E172	B:B:T173	2.82	No	No	0	6	5
406	B:B:Q176	B:B:T179	8.5	No	No	0	4	4
407	B:B:T177	B:B:T178	4.71	No	No	3	4	4
408	B:B:F180	B:B:T178	6.49	Yes	No	3	7	4
409	B:B:F180	B:B:F199	9.65	Yes	Yes	3	7	9
410	B:B:F180	B:B:W211	14.03	Yes	Yes	3	7	8
411	B:B:F180	B:B:G216	3.01	Yes	No	0	7	4
412	B:B:G182	B:B:T181	3.64	No	No	0	6	2
413	B:B:H183	B:B:V187	4.15	Yes	No	3	9	9
414	B:B:H183	B:B:S201	5.58	Yes	Yes	3	9	9
415	B:B:A203	B:B:H183	8.78	No	Yes	0	8	9
416	B:B:H183	B:B:S207	2.79	Yes	No	0	9	5
417	B:B:H183	B:B:K209	14.41	Yes	Yes	3	9	6
418	B:B:G185	B:B:T184	3.64	No	No	0	5	3
419	B:B:D205	B:B:T184	2.89	No	No	0	9	3
420	B:B:D186	B:B:M188	4.16	Yes	No	4	9	8
421	B:B:C204	B:B:D186	6.22	Yes	Yes	4	7	9
422	B:B:S201	B:B:V187	3.23	Yes	No	3	9	9
423	B:B:C204	B:B:M188	3.24	Yes	No	4	7	8
424	B:B:I232	B:B:S189	3.1	Yes	No	0	8	7
425	B:B:F199	B:B:L190	3.65	Yes	No	3	9	5
426	B:B:S191	B:B:V200	4.85	No	Yes	1	8	6
427	B:B:I232	B:B:S191	3.1	Yes	No	1	8	8
428	B:B:F234	B:B:S191	3.96	Yes	No	1	5	8
429	B:B:A193	B:B:D195	3.09	No	No	0	4	5
430	B:B:A193	B:B:L198	3.15	No	Yes	0	4	3
431	B:B:A193	B:B:F234	4.16	No	Yes	0	4	5
432	B:B:D195	B:B:P194	3.22	No	No	0	5	4
433	B:B:G238	B:B:P194	4.06	No	No	0	7	4
434	B:B:D195	B:B:R197	15.48	No	No	0	5	5
435	B:B:L198	B:B:R197	4.86	Yes	No	0	3	5
436	B:B:R197	B:B:R214	3.2	No	No	0	5	9
437	B:B:L198	B:B:L210	5.54	Yes	No	0	3	5
438	B:B:D212	B:B:L198	2.71	No	Yes	0	9	3
439	B:B:F199	B:B:W211	15.03	Yes	Yes	3	9	8
440	B:B:L210	B:B:V200	2.98	No	Yes	0	5	6
441	B:B:I232	B:B:V200	3.07	Yes	Yes	1	8	6
442	B:B:F234	B:B:V200	5.24	Yes	Yes	1	5	6
443	B:B:G202	B:B:S201	3.71	No	Yes	0	6	9
444	B:B:S201	B:B:W211	7.41	Yes	Yes	3	9	8
445	B:B:A203	B:B:D205	3.09	No	No	0	8	9
446	B:B:C204	B:B:D228	6.22	Yes	Yes	4	7	9
447	B:B:D205	B:B:S207	7.36	No	No	0	9	5
448	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
449	B:B:K209	B:B:W211	5.8	Yes	Yes	3	6	8
450	B:B:C218	B:B:K209	4.85	No	Yes	3	5	6
451	B:B:K209	B:B:T221	12.01	Yes	No	0	6	7
452	B:B:L210	B:B:R219	7.29	No	No	0	5	5
453	B:B:C218	B:B:W211	5.22	No	Yes	3	5	8
454	B:B:D212	B:B:E215	7.8	No	No	0	9	3
455	B:B:D212	B:B:R219	11.91	No	No	0	9	5
456	B:B:E215	B:B:M217	6.77	No	No	0	3	3
457	B:B:M217	B:B:R219	4.96	No	No	0	3	5
458	B:B:C218	G:G:Q18	4.58	No	No	0	5	9
459	B:B:F222	B:B:Q220	7.03	Yes	No	1	8	7
460	B:B:D258	B:B:Q220	13.05	Yes	No	1	7	7
461	B:B:Q220	G:G:I25	5.49	No	No	1	7	2
462	B:B:T221	G:G:E22	8.47	No	No	0	7	9
463	B:B:F222	B:B:F241	8.57	Yes	Yes	1	8	6
464	B:B:F222	B:B:F253	6.43	Yes	Yes	1	8	6
465	B:B:D258	B:B:F222	4.78	Yes	Yes	1	7	8
466	B:B:H225	B:B:I229	3.98	Yes	No	1	9	7
467	B:B:H225	B:B:T243	5.48	Yes	Yes	1	9	8
468	B:B:H225	B:B:S245	12.55	Yes	No	1	9	9
469	B:B:D247	B:B:H225	7.56	Yes	Yes	1	9	9
470	B:B:H225	B:B:T249	2.74	Yes	Yes	1	9	6
471	B:B:H225	B:B:R251	12.41	Yes	Yes	1	9	8
472	B:B:D228	B:B:S227	4.42	Yes	No	4	9	6
473	B:B:D246	B:B:S227	2.94	No	No	4	9	6
474	B:B:D228	B:B:D246	9.31	Yes	No	4	9	9
475	B:B:I229	B:B:T243	3.04	No	Yes	1	7	8
476	B:B:D246	B:B:N230	8.08	No	No	0	9	9
477	B:B:A231	B:B:V276	3.39	No	No	0	5	6
478	B:B:F241	B:B:I232	3.77	Yes	Yes	1	6	8
479	B:B:I232	B:B:T243	4.56	Yes	Yes	1	8	8
480	B:B:F235	B:B:P236	7.22	Yes	Yes	8	6	7
481	B:B:F235	B:B:N237	7.25	Yes	No	8	6	5
482	B:B:F235	B:B:F278	6.43	Yes	Yes	8	6	7
483	B:B:F235	B:B:G282	4.52	Yes	No	8	6	9
484	B:B:F235	G:G:L37	3.65	Yes	No	0	6	7
485	B:B:F235	G:G:Y40	4.13	Yes	Yes	8	6	6
486	B:B:F235	G:G:C41	2.79	Yes	No	0	6	7
487	B:B:F278	B:B:P236	2.89	Yes	Yes	8	7	7
488	B:B:G282	B:B:P236	4.06	No	Yes	8	9	7
489	B:B:P236	G:G:Y40	4.17	Yes	Yes	8	7	6
490	B:B:N237	B:B:N239	12.26	No	No	0	5	2
491	B:B:N237	G:G:Y40	8.14	No	Yes	8	5	6
492	B:B:N239	B:B:R256	12.05	No	No	0	2	9
493	B:B:F241	B:B:F253	10.72	Yes	Yes	1	6	6
494	B:B:A242	B:B:F278	2.77	No	Yes	0	4	7
495	B:B:G244	B:B:T243	3.64	No	Yes	0	5	8
496	B:B:F253	B:B:T243	3.89	Yes	Yes	1	6	8
497	B:B:G244	B:B:I273	3.53	No	No	0	5	6
498	B:B:D247	B:B:S245	10.31	Yes	No	1	9	9
499	B:B:D247	B:B:T249	5.78	Yes	Yes	1	9	6
500	B:B:R251	B:B:T249	5.17	Yes	Yes	1	8	6
501	B:B:S265	B:B:T249	4.8	No	Yes	0	2	6
502	B:B:C250	B:B:Y264	4.03	No	Yes	0	8	5
503	B:B:C250	B:B:I273	4.91	No	No	0	8	6
504	B:B:F253	B:B:R251	3.21	Yes	Yes	1	6	8
505	B:B:E260	B:B:R251	12.79	No	Yes	1	6	8
506	B:B:R251	B:B:T263	10.35	Yes	No	1	8	1
507	B:B:L252	B:B:L261	5.54	No	No	0	7	5
508	B:B:L252	B:B:Y264	3.52	No	Yes	0	7	5
509	B:B:E260	B:B:F253	4.66	No	Yes	1	6	6
510	B:B:A257	B:B:D254	4.63	No	Yes	0	7	9
511	B:B:D254	B:B:L261	13.57	Yes	No	0	9	5
512	B:B:R256	G:G:I28	6.26	No	No	0	9	4
513	B:B:R256	G:G:D36	4.76	No	No	0	9	5
514	B:B:D258	G:G:I25	4.2	Yes	No	1	7	2
515	B:B:Q259	G:G:V30	2.87	No	No	0	6	8
516	B:B:E260	B:B:T263	4.23	No	No	1	6	1
517	B:B:M262	B:B:Y264	9.58	Yes	Yes	0	4	5
518	B:B:A302	B:B:M262	4.83	No	Yes	0	2	4
519	B:B:L285	B:B:Y264	4.69	No	Yes	0	6	5
520	B:B:W297	B:B:Y264	5.79	No	Yes	0	8	5
521	B:B:H266	B:B:N268	8.93	No	No	0	4	4
522	B:B:H266	B:B:R304	16.93	No	No	0	4	5
523	B:B:I269	B:B:Y289	3.63	No	Yes	0	4	7
524	B:B:C271	B:B:Y289	4.03	Yes	Yes	2	5	7
525	B:B:C271	B:B:D290	3.11	Yes	Yes	2	5	6
526	B:B:C271	B:B:D291	6.22	Yes	No	2	5	8
527	B:B:I273	B:B:Y289	10.88	No	Yes	0	6	7
528	B:B:S275	B:B:T274	3.2	No	No	0	8	8
529	B:B:D290	B:B:T274	2.89	Yes	No	2	6	8
530	B:B:R314	B:B:T274	3.88	Yes	No	2	8	8
531	B:B:L318	B:B:S275	3	No	No	0	6	8
532	B:B:L318	B:B:S277	3	No	No	0	6	5
533	B:B:S277	B:B:V320	4.85	No	No	0	5	7
534	B:B:F278	B:B:L285	4.87	Yes	No	0	7	6
535	B:B:S279	G:G:D48	4.42	No	No	0	9	9
536	B:B:G324	B:B:K280	3.49	No	No	0	9	1
537	B:B:S281	G:G:D48	10.31	No	No	0	9	9
538	B:B:D298	B:B:R283	11.91	Yes	No	16	9	9
539	B:B:L300	B:B:R283	13.36	Yes	No	16	6	9
540	B:B:L284	B:B:V296	4.47	No	No	0	5	5
541	B:B:L284	G:G:L51	4.15	No	Yes	0	5	6
542	B:B:L286	B:B:V296	5.96	No	No	0	7	5
543	B:B:L286	B:B:L318	2.77	No	No	0	7	6
544	B:B:A287	B:B:Y289	4	No	Yes	0	6	7
545	B:B:D291	B:B:Y289	3.45	No	Yes	2	8	7
546	B:B:N295	B:B:Y289	5.81	No	Yes	2	6	7
547	B:B:W297	B:B:Y289	2.89	No	Yes	2	8	7
548	B:B:D290	B:B:R314	8.34	Yes	Yes	2	6	8
549	B:B:D291	B:B:N293	4.04	No	No	0	8	5
550	B:B:N293	B:B:V307	2.96	No	No	0	5	3
551	B:B:C294	B:B:L308	9.52	No	No	0	5	7
552	B:B:N295	B:B:W297	5.65	No	No	2	6	8
553	B:B:N295	B:B:R304	7.23	No	No	0	6	5
554	B:B:D298	B:B:L300	2.71	Yes	Yes	16	9	6
555	B:B:D298	B:B:K301	5.53	Yes	No	0	9	5
556	B:B:L300	G:G:C41	6.35	Yes	No	0	6	7
557	B:B:L308	B:B:W339	20.5	No	Yes	0	7	9
558	B:B:G310	B:B:K337	3.49	No	Yes	0	5	6
559	B:B:H311	B:B:V315	4.15	Yes	No	10	9	7
560	B:B:H311	B:B:T329	5.48	Yes	No	10	9	8
561	B:B:H311	B:B:S331	16.74	Yes	No	10	9	9
562	B:B:D333	B:B:H311	5.04	No	Yes	10	9	9
563	B:B:H311	B:B:K337	6.55	Yes	Yes	0	9	6
564	B:B:D312	R:R:K59	5.53	No	No	0	5	7
565	B:B:N313	B:B:W332	5.65	No	Yes	0	7	9
566	B:B:R314	B:B:W332	12	Yes	Yes	2	8	9
567	B:B:T329	B:B:V315	3.17	No	No	10	8	7
568	B:B:S331	B:B:V315	3.23	No	No	10	9	7
569	B:B:S316	B:B:W332	4.94	No	Yes	0	9	9
570	B:B:V320	B:B:V327	3.21	No	No	0	7	6
571	B:B:D323	B:B:T321	4.34	No	No	30	7	7
572	B:B:D323	B:B:M325	8.32	No	No	0	7	5
573	B:B:M325	G:G:P49	6.71	No	No	0	5	7
574	B:B:A326	G:G:F61	4.16	No	Yes	0	7	8
575	B:B:V327	B:B:W339	3.68	No	Yes	0	6	9
576	B:B:T329	B:B:W339	4.85	No	Yes	0	8	9
577	B:B:D333	B:B:S331	7.36	No	No	10	9	9
578	B:B:D333	B:B:F335	5.97	No	No	0	9	4
579	B:B:K337	B:B:W339	6.96	Yes	Yes	0	6	9
580	B:B:N340	G:G:N59	4.09	No	No	0	9	9
581	B:B:N340	G:G:F61	6.04	No	Yes	0	9	8
582	R:R:L28	R:R:P94	6.57	Yes	Yes	11	4	5
583	R:R:L28	R:R:W97	3.42	Yes	Yes	11	4	9
584	R:R:H30	R:R:T437	5.48	No	No	0	5	6
585	R:R:L181	R:R:R34	6.07	No	No	0	4	6
586	R:R:R34	R:R:T437	6.47	No	No	12	6	6
587	R:R:R34	R:R:W441	4	No	Yes	12	6	8
588	R:R:S35	R:R:S92	6.52	No	No	0	6	7
589	R:R:V37	R:R:W441	9.81	Yes	Yes	12	5	8
590	R:R:V37	W:W:?1	4.97	Yes	No	12	5	0
591	R:R:F444	R:R:L38	4.87	No	No	0	8	7
592	R:R:F41	R:R:L445	6.09	No	No	0	7	6
593	R:R:L42	R:R:S45	3	No	No	34	8	8
594	R:R:I81	R:R:L42	7.14	No	No	34	8	8
595	R:R:I81	R:R:S45	4.64	No	No	34	8	8
596	R:R:C448	R:R:S45	5.16	No	No	0	7	8
597	R:R:F46	R:R:L78	4.87	No	No	0	6	8
598	R:R:L74	R:R:N49	2.75	No	Yes	0	9	9
599	R:R:D77	R:R:N49	2.69	Yes	Yes	0	9	9
600	R:R:L78	R:R:N49	5.49	No	Yes	0	8	9
601	R:R:N49	R:R:P451	8.15	Yes	No	0	9	9
602	R:R:L52	R:R:L74	5.54	No	No	0	9	9
603	R:R:A53	R:R:L74	4.73	No	No	0	7	9
604	R:R:I465	R:R:V55	6.14	Yes	No	0	8	9
605	R:R:M468	R:R:V55	3.04	No	No	0	7	9
606	R:R:L56	R:R:N67	6.87	Yes	No	0	8	9
607	R:R:I70	R:R:L56	2.85	No	Yes	0	8	8
608	R:R:F71	R:R:L56	3.65	No	Yes	0	8	8
609	R:R:I461	R:R:L56	2.85	Yes	Yes	0	8	8
610	R:R:P60	R:R:Q57	3.16	No	No	0	7	5
611	R:R:F71	R:R:Q57	3.51	No	No	0	8	5
612	R:R:E464	R:R:K59	13.5	No	No	0	8	7
613	R:R:Q61	R:R:Q64	5.12	No	No	20	6	8
614	R:R:L62	R:R:L63	2.77	No	Yes	0	9	8
615	R:R:E464	R:R:L62	5.3	No	No	0	8	9
616	R:R:L63	R:R:T66	4.42	Yes	No	0	8	8
617	R:R:L63	R:R:N67	5.49	Yes	No	0	8	9
618	R:R:H458	R:R:L63	3.86	Yes	Yes	28	9	8
619	R:R:I461	R:R:L63	2.85	Yes	Yes	28	8	8
620	R:R:Q145	R:R:V65	4.3	No	No	0	5	7
621	R:R:D128	R:R:T66	4.34	No	No	0	9	8
622	R:R:N67	R:R:R68	4.82	No	No	0	9	8
623	R:R:R68	R:R:Y149	4.12	No	No	0	8	5
624	R:R:F69	R:R:V124	7.87	Yes	No	0	8	8
625	R:R:F71	R:R:V75	3.93	No	No	0	8	7
626	R:R:N72	R:R:T121	7.31	No	No	0	9	8
627	R:R:L152	R:R:N72	6.87	No	No	0	9	9
628	R:R:N72	R:R:W156	9.04	No	No	0	9	9
629	R:R:L73	R:R:T121	2.95	Yes	No	0	9	8
630	R:R:I122	R:R:L73	2.85	No	Yes	9	9	9
631	R:R:H450	R:R:L73	5.14	Yes	Yes	9	9	9
632	R:R:L73	R:R:Y454	4.69	Yes	Yes	9	9	9
633	R:R:D77	R:R:T76	4.34	Yes	No	0	9	9
634	R:R:C447	R:R:D77	3.11	No	Yes	0	9	9
635	R:R:D77	R:R:H450	6.3	Yes	Yes	0	9	9
636	R:R:F114	R:R:L79	6.09	Yes	No	0	7	7
637	R:R:Q80	R:R:T111	2.83	No	No	0	8	9
638	R:R:F114	R:R:Q80	9.37	Yes	No	0	7	8
639	R:R:C447	R:R:Q80	3.05	No	No	0	9	8
640	R:R:C447	R:R:I81	6.55	No	No	0	9	8
641	R:R:L83	R:R:S82	6.01	No	No	0	6	4
642	R:R:T111	R:R:V84	4.76	No	No	0	9	9
643	R:R:P94	R:R:V93	3.53	Yes	No	11	5	6
644	R:R:L95	R:R:V93	7.45	No	No	11	5	6
645	R:R:L95	R:R:P94	4.93	No	Yes	11	5	5
646	R:R:P94	R:R:W97	4.05	Yes	Yes	11	5	9
647	R:R:F96	W:W:?2	24.36	No	No	0	4	0
648	R:R:A180	R:R:W97	3.89	No	Yes	0	3	9
649	R:R:F175	R:R:L99	9.74	No	No	0	5	7
650	R:R:N100	W:W:?2	13.73	No	No	0	8	0
651	R:R:F103	W:W:?2	10.15	No	No	0	5	0
652	R:R:C104	R:R:C182	7.28	No	No	0	9	9
653	R:R:H112	R:R:V108	5.54	No	No	0	8	7
654	R:R:A173	R:R:V108	3.39	No	No	0	5	7
655	R:R:M184	R:R:V108	3.04	No	No	0	7	7
656	R:R:P166	R:R:S109	3.56	No	No	0	8	8
657	R:R:F114	R:R:L110	4.87	Yes	No	0	7	6
658	R:R:H112	R:R:Y415	5.44	No	No	0	8	9
659	R:R:L113	R:R:S163	9.01	No	No	0	8	8
660	R:R:A115	R:R:F200	2.77	No	Yes	0	8	8
661	R:R:F116	R:R:Q162	5.86	No	Yes	0	9	8
662	R:R:F116	R:R:F200	13.93	No	Yes	0	9	8
663	R:R:A117	R:R:W156	3.89	No	No	0	8	9
664	R:R:Q446	R:R:S118	5.78	No	No	9	9	9
665	R:R:H450	R:R:S118	2.79	Yes	No	9	9	9
666	R:R:N120	R:R:V119	2.96	Yes	No	0	8	9
667	R:R:P204	R:R:V119	3.53	Yes	No	0	9	9
668	R:R:N120	R:R:T155	2.92	Yes	No	0	8	8
669	R:R:N120	R:R:V158	2.96	Yes	No	36	8	5
670	R:R:N120	R:R:Q162	3.96	Yes	Yes	36	8	8
671	R:R:H450	R:R:I122	5.3	Yes	No	9	9	9
672	R:R:I122	R:R:Y454	8.46	No	Yes	9	9	9
673	R:R:P204	R:R:V123	3.53	Yes	No	0	9	7
674	R:R:D128	R:R:Y139	5.75	No	Yes	35	9	9
675	R:R:D128	R:R:M143	4.16	No	No	35	9	8
676	R:R:R129	R:R:Y212	5.14	Yes	No	0	9	9
677	R:R:R129	R:R:Y454	5.14	Yes	Yes	0	9	9
678	R:R:I134	R:R:Y130	3.63	Yes	No	37	8	9
679	R:R:C211	R:R:Y130	5.38	No	No	0	8	9
680	R:R:V214	R:R:Y130	3.79	No	No	37	6	9
681	R:R:K142	R:R:L131	5.64	No	No	0	7	6
682	R:R:S132	R:R:Y139	7.63	No	Yes	0	8	9
683	R:R:I133	R:R:I134	2.94	No	Yes	0	8	8
684	R:R:I133	R:R:V215	6.14	No	No	0	8	9
685	R:R:H135	R:R:I134	7.95	No	Yes	0	7	8
686	R:R:I134	R:R:V214	3.07	Yes	No	37	8	6
687	R:R:K142	R:R:S138	3.06	No	No	0	7	6
688	R:R:P140	R:R:Y139	4.17	No	Yes	0	7	9
689	R:R:M143	R:R:Y139	9.58	No	Yes	35	8	9
690	R:R:L150	R:R:R146	3.64	No	No	0	4	6
691	R:R:G148	R:R:L151	3.42	No	No	0	8	8
692	R:R:Q162	R:R:V158	7.16	Yes	No	36	8	5
693	R:R:Q162	R:R:S199	5.78	Yes	No	0	8	6
694	R:R:P165	R:R:T164	3.5	Yes	No	0	8	7
695	R:R:T164	R:R:Y168	4.99	No	No	0	7	6
696	R:R:P165	R:R:P166	5.84	Yes	No	19	8	8
697	R:R:P165	R:R:W170	6.76	Yes	Yes	19	8	7
698	R:R:P165	R:R:Y192	4.17	Yes	Yes	19	8	8
699	R:R:P166	R:R:Y192	8.34	No	Yes	19	8	8
700	R:R:L167	R:R:Y168	3.52	No	No	0	8	6
701	R:R:S191	R:R:W170	6.18	No	Yes	0	6	7
702	R:R:W170	R:R:Y192	2.89	Yes	Yes	19	7	8
703	R:R:G171	R:R:S189	3.71	No	No	0	7	7
704	R:R:I185	R:R:Q172	4.12	No	No	0	8	6
705	R:R:A188	R:R:Q172	3.03	No	No	0	5	6
706	R:R:C182	R:R:F175	6.98	No	No	0	9	5
707	R:R:D176	R:R:N179	5.39	No	Yes	0	4	4
708	R:R:N179	R:R:R178	9.64	Yes	No	38	4	3
709	R:R:Q433	R:R:R178	14.02	No	No	38	3	3
710	R:R:N179	R:R:Q433	9.24	Yes	No	38	4	3
711	R:R:I436	R:R:N179	7.08	No	Yes	0	6	4
712	R:R:I440	R:R:L181	2.85	No	No	0	7	4
713	R:R:M184	R:R:Y192	3.59	No	Yes	0	7	8
714	R:R:T193	R:R:W186	12.13	No	Yes	0	8	7
715	R:R:S196	R:R:W186	4.94	No	Yes	0	8	7
716	R:R:W186	R:R:Y415	5.79	Yes	No	0	7	9
717	R:R:A419	R:R:W186	10.37	No	Yes	0	8	7
718	R:R:V197	R:R:V420	4.81	No	No	0	7	7
719	R:R:F200	R:R:L412	4.87	Yes	No	0	8	9
720	R:R:C416	R:R:F200	4.19	No	Yes	0	8	8
721	R:R:C416	R:R:I201	4.91	No	No	0	8	8
722	R:R:I203	R:R:P204	3.39	No	Yes	0	7	9
723	R:R:P204	R:R:Y408	4.17	Yes	No	0	9	9
724	R:R:L205	R:R:V409	2.98	Yes	No	0	7	7
725	R:R:I405	R:R:M208	2.92	No	No	0	8	9
726	R:R:I401	R:R:Y212	6.04	No	No	0	9	9
727	R:R:I404	R:R:Y212	3.63	No	No	0	9	9
728	R:R:S213	R:R:V214	3.23	No	No	0	4	6
729	R:R:F216	R:R:R220	3.21	No	No	0	7	7
730	R:R:L225	R:R:R221	4.86	No	No	0	5	7
731	R:R:H223	R:R:Y227	9.8	No	No	0	6	5
732	R:R:I403	R:R:K399	4.36	No	No	0	8	7
733	R:R:F402	R:R:F406	4.29	No	No	0	7	6
734	R:R:I403	R:R:M457	2.92	No	No	0	8	8
735	R:R:I449	R:R:S407	3.1	No	No	0	7	7
736	R:R:L410	R:R:L442	2.77	No	No	0	5	9
737	R:R:Q446	R:R:S411	2.89	No	No	0	9	8
738	R:R:G413	R:R:P414	4.06	No	No	0	7	9
739	R:R:I439	R:R:P414	3.39	No	No	0	7	9
740	R:R:L442	R:R:P414	3.28	No	No	0	9	9
741	R:R:F443	R:R:Y415	12.38	No	No	0	8	9
742	R:R:L418	R:R:V427	4.47	No	Yes	0	7	5
743	R:R:I439	R:R:L418	5.71	No	No	0	7	7
744	R:R:L421	R:R:V425	2.98	No	No	0	6	7
745	R:R:V423	R:R:W424	19.61	No	No	0	7	6
746	R:R:D426	R:R:V427	2.92	No	Yes	7	4	5
747	R:R:D426	R:R:E428	15.59	No	No	7	4	4
748	R:R:E428	R:R:V427	4.28	No	Yes	7	4	5
749	R:R:V427	R:R:V431	4.81	Yes	Yes	7	5	6
750	R:R:P432	R:R:V431	3.53	No	Yes	7	6	6
751	R:R:V431	R:R:V435	3.21	Yes	No	7	6	5
752	R:R:P432	R:R:W434	9.46	No	No	7	6	4
753	R:R:P432	R:R:V435	5.3	No	No	7	6	5
754	R:R:V435	R:R:W434	8.58	No	No	7	5	4
755	R:R:T437	R:R:W441	4.85	No	Yes	12	6	8
756	R:R:I438	R:R:L442	2.85	No	No	0	6	9
757	R:R:W441	W:W:?1	15.19	Yes	No	12	8	0
758	R:R:I449	R:R:L445	2.85	No	No	0	7	6
759	R:R:H450	R:R:Q446	11.13	Yes	No	9	9	9
760	R:R:Y452	R:R:Y456	7.94	No	Yes	0	7	8
761	R:R:V453	R:R:Y454	10.09	No	Yes	0	9	9
762	R:R:K462	R:R:Y456	4.78	No	Yes	29	8	8
763	R:R:Q466	R:R:Y456	4.51	No	Yes	29	7	8
764	R:R:H458	R:R:T460	9.58	Yes	No	0	9	8
765	R:R:H458	R:R:I461	5.3	Yes	Yes	28	9	8
766	R:R:I461	R:R:I465	2.94	Yes	Yes	0	8	8
767	R:R:K462	R:R:Q466	5.42	No	No	29	8	7
768	R:R:D467	R:R:K463	4.15	No	No	0	6	6
769	R:R:F472	R:R:F473	13.93	No	No	0	1	4
770	G:G:N5	G:G:T6	4.39	No	No	0	4	3
771	G:G:I9	G:G:T6	7.6	No	No	0	2	3
772	G:G:M21	G:G:Q18	4.08	No	No	0	1	9
773	G:G:E22	G:G:Q18	7.65	No	No	0	9	9
774	G:G:I25	G:G:R27	8.77	No	Yes	0	2	8
775	G:G:I28	G:G:K32	5.82	No	No	0	4	5
776	G:G:H44	G:G:Y40	8.71	No	Yes	0	6	6
777	G:G:A43	G:G:H44	2.93	No	No	0	4	6
778	G:G:E47	G:G:H44	7.39	No	No	0	3	6
779	G:G:D48	G:G:L51	10.86	No	Yes	0	9	6
780	G:G:P49	G:G:V54	3.53	No	No	0	7	6
781	G:G:L51	G:G:T52	4.42	Yes	No	0	6	4
782	G:G:P55	G:G:V54	5.3	No	No	0	5	6
783	G:G:N59	G:G:V54	4.43	No	No	0	9	6
784	G:G:E58	G:G:P55	6.29	No	No	0	5	5
785	G:G:E58	G:G:S57	7.19	No	No	0	5	6
786	G:G:F61	G:G:P60	5.78	Yes	No	31	8	9
787	A:A:L388	A:A:Q384	2.66	No	Yes	0	8	6
788	A:A:H387	A:A:I383	2.65	No	No	0	8	8
789	R:R:F200	R:R:S196	2.64	Yes	No	0	8	8
790	B:B:F199	B:B:V213	2.62	Yes	No	0	9	4
791	R:R:F41	R:R:V37	2.62	No	Yes	0	7	5
792	R:R:F69	R:R:V65	2.62	Yes	No	0	8	7
793	R:R:F69	R:R:V125	2.62	Yes	No	0	8	9
794	R:R:R129	R:R:V125	2.62	Yes	No	0	9	9
795	A:A:D381	R:R:Q222	2.61	No	No	0	8	8
796	B:B:D247	B:B:E226	2.6	Yes	No	0	9	3
797	B:B:R49	B:B:T87	2.59	No	No	0	7	5
798	R:R:F175	R:R:T91	2.59	No	No	0	5	7
799	R:R:F443	R:R:T111	2.59	No	No	0	8	9
800	R:R:R147	R:R:T144	2.59	No	No	0	8	9
801	B:B:S147	B:B:Y145	2.54	No	Yes	0	9	8
802	B:B:V71	B:B:Y105	2.52	No	Yes	0	8	6
803	B:B:V112	B:B:Y105	2.52	No	Yes	0	8	6
804	A:A:I62	A:A:R61	2.51	No	No	0	9	8
805	A:A:I276	A:A:R231	2.51	No	No	0	8	9
806	A:A:F345	A:A:I341	2.51	Yes	No	0	8	8
807	R:R:F46	R:R:I50	2.51	No	No	0	6	6
808	R:R:F216	R:R:I401	2.51	No	No	0	7	9
809	A:A:T335	A:A:Y339	2.5	No	Yes	0	4	3
810	A:A:K307	A:A:R333	2.48	No	No	0	6	5
811	R:R:M468	R:R:R58	2.48	No	No	0	7	7
812	R:R:S189	R:R:W170	2.47	No	Yes	0	7	7
813	B:B:F222	B:B:L255	2.44	Yes	No	1	8	6
814	B:B:F234	B:B:L255	2.44	Yes	No	1	5	6
815	B:B:F241	B:B:L255	2.44	Yes	No	1	6	6
816	R:R:F96	R:R:L95	2.44	No	No	0	4	5
817	R:R:F103	R:R:L99	2.44	No	No	0	5	7
818	R:R:F114	R:R:L113	2.44	Yes	No	0	7	8
819	R:R:F406	R:R:L410	2.44	No	No	0	6	5
820	R:R:F473	R:R:L469	2.44	No	No	0	4	8
821	A:A:L346	A:A:R342	2.43	No	Yes	0	4	4
822	B:B:L7	G:G:R13	2.43	Yes	No	0	8	6
823	B:B:L192	B:B:R150	2.43	No	No	0	5	6
824	R:R:I465	R:R:Y456	2.42	Yes	Yes	0	8	8
825	G:G:N59	G:G:R62	2.41	No	No	0	9	7
826	R:R:M208	R:R:Y408	2.39	No	No	0	9	9
827	A:A:R228	B:B:D186	2.38	No	Yes	0	9	9
828	R:R:L226	R:R:Y227	2.34	Yes	No	0	5	5
829	A:A:N254	A:A:Y311	2.33	No	No	0	9	6
830	R:R:L38	R:R:W441	2.28	No	Yes	0	7	8
831	R:R:L107	R:R:W87	2.28	No	No	0	7	6
832	R:R:L195	R:R:W170	2.28	No	Yes	0	6	7
833	A:A:N279	A:A:W281	2.26	No	Yes	0	8	5
834	B:B:G115	B:B:G116	2.11	No	No	0	9	9
835	B:B:G324	G:G:P49	2.03	No	No	0	9	7
836	B:B:C271	B:B:G272	1.96	Yes	No	0	5	4
837	B:B:C317	B:B:G330	1.96	No	No	0	7	5
838	A:A:A303	A:A:G304	1.95	No	No	0	5	5
839	B:B:A106	B:B:G109	1.95	No	No	0	6	5
840	B:B:A140	B:B:G141	1.95	No	No	0	5	5
841	B:B:A309	B:B:G310	1.95	No	No	0	3	5
842	A:A:A39	R:R:P140	1.87	No	No	0	5	7
843	R:R:A85	R:R:P86	1.87	No	No	0	8	9
844	A:A:G52	A:A:S51	1.86	No	No	0	9	9
845	A:A:G52	A:A:S366	1.86	No	No	0	9	9
846	A:A:G353	A:A:S352	1.86	No	No	0	4	5
847	B:B:G77	B:B:S98	1.86	No	No	0	8	8
848	B:B:G288	B:B:S275	1.86	No	No	0	7	8
849	B:B:G319	B:B:S277	1.86	No	No	0	5	5
850	R:R:G31	R:R:S92	1.86	No	No	0	5	7
851	B:B:G244	B:B:V276	1.84	No	No	0	5	6
852	B:B:G306	B:B:V296	1.84	No	No	0	4	5
853	R:R:G48	R:R:V47	1.84	No	No	0	9	5
854	B:B:G115	B:B:T102	1.82	No	No	0	9	8
855	B:B:A60	B:B:C103	1.81	No	No	0	7	8
856	B:B:A104	B:B:C149	1.81	No	No	0	7	8
857	B:B:A113	B:B:C149	1.81	No	No	0	9	8
858	R:R:A398	R:R:C395	1.81	No	No	0	8	7
859	R:R:A117	R:R:A159	1.79	No	No	0	8	9
860	R:R:A219	R:R:A397	1.79	No	No	0	8	8
861	R:R:P190	R:R:S189	1.78	No	No	0	4	7
862	R:R:G154	R:R:I157	1.76	No	No	0	4	5
863	R:R:G413	R:R:I201	1.76	No	No	0	7	8
864	R:R:G455	R:R:I461	1.76	No	Yes	0	8	8
865	A:A:P326	A:A:T325	1.75	No	No	0	1	2
866	B:B:P107	B:B:T65	1.75	No	No	0	6	1
867	G:G:P53	G:G:T52	1.75	No	No	0	8	4
868	B:B:G53	B:B:K89	1.74	No	Yes	0	9	9
869	A:A:G47	A:A:L46	1.71	No	Yes	0	9	8
870	B:B:A56	B:B:S74	1.71	No	No	0	7	9
871	B:B:G174	B:B:L139	1.71	No	Yes	0	4	9
872	B:B:C233	B:B:V276	1.71	No	No	0	3	6
873	R:R:C211	R:R:V127	1.71	No	No	0	8	7
874	R:R:C416	R:R:V197	1.71	No	No	0	8	7
875	R:R:C211	R:R:V207	1.71	No	No	0	8	7
876	A:A:A269	A:A:V248	1.7	No	No	0	9	7
877	A:A:A298	A:A:V334	1.7	No	Yes	0	4	4
878	A:A:A337	A:A:V301	1.7	No	No	0	8	7
879	B:B:A11	G:G:V16	1.7	No	No	0	5	7
880	B:B:A305	B:B:V40	1.7	No	Yes	0	4	3
881	B:B:A257	G:G:V30	1.7	No	No	0	7	8
882	A:A:D354	A:A:G353	1.68	No	No	0	3	4
883	A:A:D354	A:A:G355	1.68	No	No	0	3	2
884	R:R:A173	R:R:T105	1.68	No	No	0	5	7
885	A:A:C379	A:A:I375	1.64	No	No	0	8	9
886	R:R:G171	R:R:Q172	1.64	No	No	0	7	6
887	R:R:S138	R:R:S141	1.63	No	No	0	6	5
888	A:A:I26	B:B:A92	1.62	No	No	0	9	6
889	A:A:A243	A:A:I288	1.62	No	No	0	8	9
890	A:A:A243	A:A:I382	1.62	No	No	0	8	6
891	A:A:A337	A:A:I308	1.62	No	No	0	8	7
892	B:B:A28	B:B:I33	1.62	No	No	0	4	3
893	B:B:I33	G:G:A34	1.62	No	No	0	3	6
894	B:B:A140	B:B:I120	1.62	No	No	0	5	6
895	B:B:A248	B:B:I269	1.62	No	No	0	5	4
896	R:R:S126	R:R:V127	1.62	No	No	0	9	7
897	R:R:S126	R:R:V207	1.62	No	No	0	9	7
898	R:R:A218	R:R:I134	1.62	No	Yes	0	7	8
899	R:R:S407	R:R:V453	1.62	No	No	0	7	9
900	A:A:S54	A:A:T55	1.6	No	No	0	9	9
901	B:B:S31	B:B:T29	1.6	No	No	0	1	3
902	B:B:S207	B:B:T223	1.6	No	No	0	5	2
903	R:R:V39	R:R:V89	1.6	No	No	0	5	8
904	R:R:V47	R:R:V51	1.6	No	No	0	5	8
905	A:A:T55	A:A:V367	1.59	No	No	0	9	9
906	A:A:T210	A:A:V57	1.59	No	No	0	7	7
907	A:A:T335	A:A:V334	1.59	No	Yes	0	4	4
908	R:R:G31	R:R:H30	1.59	No	No	0	5	5
909	B:B:A11	G:G:L19	1.58	No	Yes	0	5	9
910	R:R:A85	R:R:L42	1.58	No	No	0	8	8
911	A:A:T204	B:B:T143	1.57	No	No	0	9	5
912	A:A:A19	B:B:N88	1.56	No	Yes	0	4	7
913	A:A:A226	B:B:N119	1.56	No	Yes	0	9	9
914	G:G:A23	G:G:N24	1.56	No	No	0	8	1
915	B:B:A240	B:B:D254	1.54	No	Yes	0	6	9
916	B:B:D254	G:G:A33	1.54	Yes	No	0	9	7
917	R:R:I33	R:R:V37	1.54	No	Yes	0	4	5
918	R:R:I465	R:R:V51	1.54	Yes	No	0	8	8
919	R:R:I203	R:R:V198	1.54	No	No	0	7	7
920	R:R:I206	R:R:V202	1.54	No	No	0	4	6
921	R:R:I404	R:R:V400	1.54	No	No	0	9	8
922	R:R:I436	R:R:V431	1.54	No	Yes	0	6	6
923	B:B:Q17	G:G:A23	1.52	No	No	0	4	8
924	R:R:I32	R:R:T36	1.52	No	No	0	5	4
925	R:R:I160	R:R:T164	1.52	No	No	0	5	7
926	B:B:F253	B:B:G224	1.51	Yes	No	0	6	6
927	R:R:F69	R:R:G148	1.51	Yes	No	0	8	8
928	A:A:L291	A:A:S250	1.5	No	No	0	8	6
929	A:A:L296	A:A:S251	1.5	No	No	0	6	9
930	R:R:L28	R:R:S92	1.5	Yes	No	0	4	7
931	B:B:L7	G:G:V16	1.49	Yes	No	0	8	7
932	R:R:L38	R:R:V88	1.49	No	No	0	7	8
933	R:R:L107	R:R:V84	1.49	No	No	0	7	9
934	R:R:L421	R:R:V427	1.49	No	Yes	0	6	5
935	B:B:D322	B:B:S67	1.47	No	No	0	1	5
936	R:R:I209	R:R:I405	1.47	No	No	39	6	8
937	A:A:N218	A:A:T40	1.46	No	No	0	4	7
938	A:A:D331	A:A:V334	1.46	Yes	Yes	0	4	4
939	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
940	R:R:G154	R:R:Y153	1.45	No	No	0	4	5
941	R:R:G169	R:R:Y168	1.45	No	No	0	8	6
942	A:A:F312	A:A:P313	1.44	No	No	0	8	6
943	B:B:I18	G:G:L19	1.43	No	Yes	0	7	9
944	R:R:I32	R:R:L28	1.43	No	Yes	0	5	4
945	R:R:I50	R:R:L54	1.43	No	No	0	6	5
946	R:R:I157	R:R:L161	1.43	No	No	0	5	5
947	R:R:I201	R:R:L205	1.43	No	Yes	0	8	7
948	R:R:I209	R:R:L205	1.43	No	Yes	39	6	7
949	R:R:I405	R:R:L205	1.43	No	Yes	39	8	7
950	R:R:I465	R:R:L469	1.43	Yes	No	0	8	8
951	B:B:Q175	B:B:T173	1.42	No	No	0	4	5
952	A:A:R232	B:B:C204	1.39	No	Yes	0	8	7
953	B:B:C25	G:G:R27	1.39	No	Yes	0	3	8
954	B:B:H54	B:B:S334	1.39	Yes	No	0	9	4
955	B:B:A299	B:B:F278	1.39	No	Yes	0	5	7
956	A:A:A48	A:A:R265	1.38	No	Yes	0	8	9
957	A:A:A316	A:A:R336	1.38	No	No	0	2	5
958	B:B:I37	G:G:E42	1.37	No	No	0	2	1
959	A:A:K216	A:A:Q213	1.36	No	No	0	4	3
960	A:A:D378	A:A:N377	1.35	Yes	No	0	7	4
961	B:B:D267	B:B:N268	1.35	No	No	0	3	4
962	R:R:P98	R:R:W97	1.35	No	Yes	0	4	9
963	R:R:H135	R:R:L131	1.29	No	No	0	7	6
964	R:R:R146	R:R:T144	1.29	No	No	0	6	9
965	B:B:E12	B:B:Q9	1.27	No	No	0	4	3
966	R:R:V425	R:R:W424	1.23	No	No	0	7	6
967	R:R:F114	R:R:L83	1.22	Yes	No	0	7	6
968	B:B:F292	B:B:N313	1.21	No	No	0	4	7
969	A:A:D49	A:A:R265	1.19	No	Yes	0	8	9
970	A:A:D381	R:R:R221	1.19	No	No	0	8	7
971	A:A:Q59	A:A:Y63	1.13	No	No	0	9	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:K34	4.46	4	20	4
2	A:A:H41	4.1375	4	22	6
3	A:A:L46	3.4375	4	23	8
4	A:A:F212	5.55	4	0	9
5	A:A:F219	5.63	5	22	8
6	A:A:Q227	3.8325	4	4	9
7	A:A:K233	4.7125	4	4	9
8	A:A:W234	4.942	5	0	9
9	A:A:F238	5.942	5	0	9
10	A:A:R265	5.03	5	24	9
11	A:A:L270	5.4725	4	0	6
12	A:A:W277	7.616	5	25	6
13	A:A:W281	8.296	5	2	5
14	A:A:N292	4.65	5	0	9
15	A:A:D331	5.2075	4	0	4
16	A:A:V334	1.9325	4	0	4
17	A:A:Y339	4.9875	4	0	3
18	A:A:R342	4.65	4	0	4
19	A:A:F345	5.806	5	0	8
20	A:A:Y358	4.818	5	15	4
21	A:A:Y360	5.51	4	15	8
22	A:A:F363	7.16	4	26	5
23	A:A:T364	6.3625	4	13	9
24	A:A:N371	3.635	4	13	9
25	A:A:R374	5.405	4	13	4
26	A:A:D378	7.355	4	0	7
27	A:A:Q384	4.005	4	27	6
28	A:A:R385	8.295	4	15	5
29	A:A:L393	2.9375	4	0	8
30	B:B:L7	3.43	4	0	8
31	B:B:L30	4.385	4	0	5
32	B:B:V40	4.9575	4	16	3
33	B:B:H54	6.665	6	5	9
34	B:B:K57	7.322	5	2	9
35	B:B:Y59	5.238	5	2	8
36	B:B:W63	5.135	4	0	7
37	B:B:Q75	7.4075	4	2	9
38	B:B:D76	8.1375	4	0	9
39	B:B:W82	7.28429	7	5	9
40	B:B:N88	4.075	4	0	7
41	B:B:K89	5.552	5	5	9
42	B:B:H91	4.9425	4	0	5
43	B:B:L95	4.0675	4	17	8
44	B:B:W99	6.746	5	0	9
45	B:B:Y105	3.435	4	0	6
46	B:B:N119	3.925	4	0	9
47	B:B:I123	3.838	5	33	6
48	B:B:Y124	5.345	4	17	6
49	B:B:T128	4.8675	4	18	3
50	B:B:L139	5.1375	4	0	9
51	B:B:H142	5.64429	7	6	9
52	B:B:Y145	4.52429	7	4	8
53	B:B:D163	7.8025	4	6	9
54	B:B:W169	7.26167	6	6	8
55	B:B:F180	7.474	5	3	7
56	B:B:H183	7.142	5	3	9
57	B:B:D186	4.762	5	4	9
58	B:B:L198	4.065	4	0	3
59	B:B:F199	6.976	5	3	9
60	B:B:V200	4.035	4	1	6
61	B:B:S201	4.9825	4	3	9
62	B:B:C204	4.384	5	4	7
63	B:B:K209	9.2675	4	3	6
64	B:B:W211	9.498	5	3	8
65	B:B:F222	5.85	5	1	8
66	B:B:H225	6.59714	7	1	9
67	B:B:D228	6.37	4	4	9
68	B:B:I232	3.52	5	1	8
69	B:B:F234	3.95	4	1	5
70	B:B:F235	5.14143	7	8	6
71	B:B:P236	4.585	4	8	7
72	B:B:F241	5.654	5	1	6
73	B:B:T243	4.122	5	1	8
74	B:B:D247	6.5625	4	1	9
75	B:B:T249	4.6225	4	1	6
76	B:B:R251	8.786	5	1	8
77	B:B:F253	5.07	6	1	6
78	B:B:D254	5.32	4	0	9
79	B:B:D258	7.295	4	1	7
80	B:B:M262	5.43	4	0	4
81	B:B:Y264	5.522	5	0	5
82	B:B:C271	3.83	4	2	5
83	B:B:F278	3.67	5	8	7
84	B:B:Y289	4.95571	7	2	7
85	B:B:D290	4.7025	4	2	6
86	B:B:D298	6.8625	4	16	9
87	B:B:L300	6.71	4	16	6
88	B:B:H311	7.592	5	10	9
89	B:B:R314	8.305	4	2	8
90	B:B:W332	7.48167	6	2	9
91	B:B:L336	3.7025	4	5	7
92	B:B:K337	5.375	4	0	6
93	B:B:W339	7.79333	6	0	9
94	R:R:L28	3.23	4	11	4
95	R:R:V37	4.735	4	12	5
96	R:R:N49	4.77	4	0	9
97	R:R:L56	4.055	4	0	8
98	R:R:L63	3.878	5	28	8
99	R:R:F69	3.655	4	0	8
100	R:R:L73	3.9075	4	9	9
101	R:R:D77	4.11	4	0	9
102	R:R:P94	4.77	4	11	5
103	R:R:W97	3.1775	4	11	9
104	R:R:F114	4.798	5	0	7
105	R:R:N120	3.2	4	36	8
106	R:R:R129	6.3125	4	0	9
107	R:R:I134	3.842	5	37	8
108	R:R:Y139	6.7825	4	35	9
109	R:R:Q162	5.69	4	36	8
110	R:R:P165	5.0675	4	19	8
111	R:R:W170	4.116	5	19	7
112	R:R:N179	7.8375	4	38	4
113	R:R:W186	8.3075	4	0	7
114	R:R:Y192	4.7475	4	19	8
115	R:R:F200	5.68	5	0	8
116	R:R:P204	3.655	4	0	9
117	R:R:L205	1.8175	4	39	7
118	R:R:L226	4.605	4	15	5
119	R:R:V427	3.594	5	7	5
120	R:R:V431	3.2725	4	7	6
121	R:R:W441	7.226	5	12	8
122	R:R:H450	6.132	5	9	9
123	R:R:Y454	7.095	4	9	9
124	R:R:Y456	4.9125	4	29	8
125	R:R:H458	6.59	4	28	9
126	R:R:I461	3.14	5	28	8
127	R:R:I465	2.894	5	0	8
128	G:G:L19	2.15	4	0	9
129	G:G:R27	4.0325	4	0	8
130	G:G:Y40	6.2875	4	8	6
131	G:G:L51	5.6025	4	0	6
132	G:G:F61	5.226	5	31	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:S84	B:B:W63	10.6563	6.18	No	Yes	0	5	7
2	B:B:L70	B:B:W63	16.9993	6.83	No	Yes	0	5	7
3	B:B:L70	B:B:W82	17.3632	4.56	No	Yes	0	5	9
4	B:B:H54	B:B:W82	20.5598	3.17	Yes	Yes	5	9	9
5	B:B:H54	B:B:S74	23.1209	12.55	Yes	No	0	9	9
6	B:B:D76	B:B:S74	23.828	7.36	Yes	No	0	9	9
7	B:B:D76	B:B:K78	17.7407	6.91	Yes	No	0	9	8
8	B:B:K78	B:B:P94	16.2829	3.35	No	No	0	8	5
9	B:B:I93	B:B:P94	15.9169	3.39	No	No	0	7	5
10	B:B:D76	B:B:L55	40.7171	14.93	Yes	No	0	9	6
11	A:A:K34	B:B:L55	80.3478	5.64	Yes	No	0	4	6
12	A:A:K34	R:R:Q64	79.923	2.71	Yes	No	20	4	8
13	A:A:Y37	B:B:L55	87.1064	3.52	No	No	0	4	6
14	A:A:R42	A:A:Y37	87.25	12.35	No	No	0	9	4
15	A:A:R38	R:R:Q64	79.9791	21.03	No	No	0	4	8
16	A:A:R38	R:R:P140	79.8873	2.88	No	No	0	4	7
17	A:A:F212	A:A:M60	16.2965	4.98	Yes	No	0	9	9
18	A:A:M60	A:A:Q59	16.8494	8.16	No	No	0	9	9
19	A:A:N371	A:A:Q59	17.9533	3.96	Yes	No	0	9	9
20	A:A:N371	A:A:R374	18.2344	3.62	Yes	Yes	13	9	4
21	A:A:H362	A:A:R374	33.1365	6.77	No	Yes	0	9	4
22	A:A:D378	A:A:H362	47.4685	8.82	Yes	No	0	7	9
23	A:A:D378	A:A:Y360	49.0159	8.05	Yes	Yes	0	7	8
24	A:A:R385	A:A:Y360	13.833	6.17	Yes	Yes	15	5	8
25	A:A:R385	R:R:Q222	42.1091	11.68	Yes	No	0	5	8
26	A:A:Q384	R:R:Q222	40.987	5.12	Yes	No	0	6	8
27	A:A:L388	A:A:Q384	39.6056	2.66	No	Yes	0	8	6
28	A:A:L388	A:A:L393	34.6631	2.77	No	Yes	0	8	8
29	A:A:L393	R:R:I401	37.3677	2.85	Yes	No	0	8	9
30	R:R:I401	R:R:Y212	37.9857	6.04	No	No	0	9	9
31	R:R:R129	R:R:Y212	38.6165	5.14	Yes	No	0	9	9
32	A:A:Y391	R:R:R129	74.5385	12.35	No	Yes	0	4	9
33	A:A:Y391	R:R:H458	74.5916	7.62	No	Yes	0	4	9
34	R:R:H458	R:R:L63	71.1701	3.86	Yes	Yes	28	9	8
35	R:R:L63	R:R:T66	79.2551	4.42	Yes	No	0	8	8
36	R:R:D128	R:R:T66	79.3435	4.34	No	No	0	9	8
37	R:R:D128	R:R:Y139	79.2848	5.75	No	Yes	35	9	9
38	R:R:P140	R:R:Y139	79.7043	4.17	No	Yes	0	7	9
39	A:A:F222	A:A:R42	87.6678	3.21	No	No	0	7	9
40	A:A:F222	B:B:W99	88.4136	10.02	No	Yes	0	7	9
41	A:A:F238	A:A:L44	40.3199	10.96	Yes	No	0	9	9
42	A:A:L44	A:A:L46	39.963	5.54	No	Yes	23	9	8
43	A:A:F246	A:A:L46	40.2193	3.65	No	Yes	0	9	8
44	A:A:D249	A:A:K293	13.4395	17.97	No	No	0	9	9
45	A:A:K293	A:A:N292	14.5555	4.2	No	Yes	0	9	9
46	A:A:N292	A:A:T364	25.6826	4.39	Yes	Yes	0	9	9
47	A:A:F290	A:A:T364	13.2728	11.67	No	Yes	0	9	9
48	A:A:F290	A:A:H362	13.8072	5.66	No	No	0	9	9
49	A:A:R374	A:A:T364	13.2768	6.47	Yes	Yes	13	4	9
50	B:B:L117	B:B:W99	17.6779	5.69	No	Yes	0	9	9
51	B:B:L117	B:B:Y145	16.7506	3.52	No	Yes	4	9	8
52	A:A:R231	A:A:W234	20.1206	6	No	Yes	0	9	9
53	A:A:D272	A:A:R231	19.7928	10.72	No	No	0	8	9
54	B:B:Q75	B:B:W99	64.0806	5.48	Yes	Yes	0	9	9
55	B:B:K57	B:B:Q75	32.1877	6.78	Yes	Yes	2	9	9
56	B:B:K57	B:B:W332	30.9556	13.92	Yes	Yes	2	9	9
57	B:B:R314	B:B:W332	100	12	Yes	Yes	2	8	9
58	B:B:Q75	B:B:Y59	32.0187	11.27	Yes	Yes	2	9	8
59	B:B:W332	B:B:Y59	70.7681	3.86	Yes	Yes	2	9	8
60	A:A:C237	A:A:F238	33.1526	2.79	No	Yes	0	8	9
61	A:A:F246	A:A:L289	60.0055	3.65	No	No	0	9	9
62	A:A:F345	A:A:L289	68.6587	4.87	Yes	No	0	8	9
63	A:A:F345	A:A:L270	26.0825	9.74	Yes	Yes	0	8	6
64	A:A:I348	A:A:L270	25.4209	2.85	No	Yes	0	4	6
65	A:A:F273	A:A:I348	22.1464	6.28	No	No	0	9	4
66	A:A:F273	A:A:F345	44.649	5.36	No	Yes	0	9	8
67	A:A:C359	A:A:F273	22.6623	2.79	No	No	0	5	9
68	A:A:I348	A:A:K274	47.3082	4.36	No	No	0	4	5
69	A:A:K274	A:A:N278	47.1086	4.2	No	No	0	5	8
70	A:A:C359	A:A:S349	22.622	3.44	No	No	0	5	7
71	A:A:S349	A:A:W277	22.542	3.71	No	Yes	0	7	6
72	A:A:N278	A:A:S352	46.885	5.96	No	No	25	8	5
73	A:A:S352	A:A:W277	22.4632	4.94	No	Yes	25	5	6
74	B:B:D290	B:B:R314	73.1229	8.34	Yes	Yes	2	6	8
75	A:A:L289	A:A:L291	20.4702	2.77	No	No	0	9	8
76	A:A:F363	A:A:L291	19.3535	3.65	Yes	No	0	5	8
77	A:A:T335	A:A:Y339	13.6939	2.5	No	Yes	0	4	3
78	A:A:T335	A:A:V334	10.2786	1.59	No	Yes	0	4	4
79	A:A:D354	A:A:G355	68.2534	1.68	No	No	0	3	2
80	A:A:D354	A:A:G353	68.6175	1.68	No	No	0	3	4
81	A:A:G353	A:A:S352	68.9823	1.86	No	No	0	4	5
82	A:A:R385	A:A:Y358	28.0798	9.26	Yes	Yes	15	5	4
83	A:A:G355	A:A:Y358	67.8914	2.9	No	Yes	0	2	4
84	B:B:C271	B:B:D290	74.4549	3.11	Yes	Yes	2	5	6
85	B:B:C271	B:B:Y289	72.0638	4.03	Yes	Yes	2	5	7
86	B:B:I273	B:B:Y289	42.4354	10.88	No	Yes	0	6	7
87	B:B:G244	B:B:I273	43.2479	3.53	No	No	0	5	6
88	B:B:G244	B:B:T243	41.2593	3.64	No	Yes	0	5	8
89	B:B:F253	B:B:T243	20.9958	3.89	Yes	Yes	1	6	8
90	B:B:F222	B:B:F253	16.4216	6.43	Yes	Yes	1	8	6
91	B:B:D258	B:B:F222	12.8978	4.78	Yes	Yes	1	7	8
92	B:B:D258	B:B:R22	10.2261	7.15	Yes	No	0	7	6
93	B:B:W297	B:B:Y289	25.6626	2.89	No	Yes	2	8	7
94	B:B:W297	B:B:Y264	25.2694	5.79	No	Yes	0	8	5
95	B:B:R314	B:B:T274	22.7241	3.88	Yes	No	2	8	8
96	B:B:S275	B:B:T274	23.728	3.2	No	No	0	8	8
97	B:B:L318	B:B:S275	22.6986	3	No	No	0	6	8
98	B:B:L318	B:B:S277	15.3104	3	No	No	0	6	5
99	B:B:S277	B:B:V320	14.2326	4.85	No	No	0	5	7
100	B:B:V320	B:B:V327	13.6927	3.21	No	No	0	7	6
101	B:B:V327	B:B:W339	13.1523	3.68	No	Yes	0	6	9
102	B:B:M101	B:B:Y145	10.2795	3.59	No	Yes	0	9	8
103	B:B:S147	B:B:Y145	18.9551	2.54	No	Yes	0	9	8
104	B:B:S147	B:B:S160	18.5828	3.26	No	No	0	9	6
105	B:B:S160	B:B:V187	18.2099	6.46	No	No	0	6	9
106	B:B:S201	B:B:V187	11.6321	3.23	Yes	No	3	9	9
107	B:B:S201	B:B:W211	10.9517	7.41	Yes	Yes	3	9	8
108	B:B:I93	B:B:L79	10.3549	4.28	No	No	0	7	7
109	B:B:G162	B:B:Y145	15.9603	5.79	No	Yes	0	9	8
110	B:B:G162	B:B:S161	15.5831	3.71	No	No	0	9	9
111	B:B:H142	B:B:S161	12.866	13.95	Yes	No	6	9	9
112	B:B:I232	B:B:T243	14.7342	4.56	Yes	Yes	1	8	8
113	B:B:L285	B:B:Y264	12.5203	4.69	No	Yes	0	6	5
114	B:B:F278	B:B:L285	12.0032	4.87	Yes	No	0	7	6
115	R:R:R129	R:R:Y454	90.8902	5.14	Yes	Yes	0	9	9
116	R:R:V453	R:R:Y454	15.2874	10.09	No	Yes	0	9	9
117	R:R:S407	R:R:V453	14.8963	1.62	No	No	0	7	9
118	R:R:I449	R:R:S407	14.5046	3.1	No	No	0	7	7
119	R:R:I449	R:R:L445	14.1123	2.85	No	No	0	7	6
120	R:R:F41	R:R:L445	13.7194	6.09	No	No	0	7	6
121	R:R:F41	R:R:V37	13.3259	2.62	No	Yes	0	7	5
122	R:R:V37	R:R:W441	12.1326	9.81	Yes	Yes	12	5	8
123	R:R:L73	R:R:Y454	41.4211	4.69	Yes	Yes	9	9	9
124	R:R:H450	R:R:L73	39.2666	5.14	Yes	Yes	9	9	9
125	R:R:D77	R:R:H450	75.7112	6.3	Yes	Yes	0	9	9
126	R:R:C447	R:R:D77	68.47	3.11	No	Yes	0	9	9
127	R:R:I122	R:R:Y454	39.3671	8.46	No	Yes	9	9	9
128	R:R:H450	R:R:I122	39.0591	5.3	Yes	No	9	9	9
129	R:R:C447	R:R:Q80	63.8237	3.05	No	No	0	9	8
130	R:R:Q80	R:R:T111	58.4774	2.83	No	No	0	8	9
131	R:R:F443	R:R:T111	55.7891	2.59	No	No	0	8	9
132	R:R:F443	R:R:Y415	55.1156	12.38	No	No	0	8	9
133	R:R:H112	R:R:Y415	16.4362	5.44	No	No	0	8	9
134	R:R:H112	R:R:V108	15.7285	5.54	No	No	0	8	7
135	R:R:M184	R:R:V108	13.6009	3.04	No	No	0	7	7
136	R:R:M184	R:R:Y192	12.8905	3.59	No	Yes	0	7	8
137	R:R:W186	R:R:Y415	38.7716	5.79	Yes	No	0	7	9
138	R:R:S196	R:R:W186	36.704	4.94	No	Yes	0	8	7
139	R:R:F200	R:R:S196	36.0136	2.64	Yes	No	0	8	8
140	R:R:I133	R:R:I134	10.683	2.94	No	Yes	0	8	8
141	R:R:C416	R:R:F200	25.5275	4.19	No	Yes	0	8	8
142	R:R:C416	R:R:I201	23.4299	4.91	No	No	0	8	8
143	R:R:G413	R:R:I201	18.5568	1.76	No	No	0	7	8
144	R:R:G413	R:R:P414	17.8506	4.06	No	No	0	7	9
145	R:R:I439	R:R:P414	13.6009	3.39	No	No	0	7	9
146	R:R:I439	R:R:L418	12.8905	5.71	No	No	0	7	7
147	R:R:L418	R:R:V427	12.1795	4.47	No	Yes	0	7	5
148	A:A:Y358	A:A:Y360	37.3017	2.98	Yes	Yes	15	4	8
149	A:A:D272	A:A:F246	19.6337	8.36	No	No	0	8	9
150	A:A:W234	B:B:Y145	18.7879	4.82	Yes	Yes	0	9	8
151	A:A:C237	B:B:Y59	32.3271	2.69	No	Yes	2	8	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:R34	R:R:T437	6.47	12	No	No	6	6	2	2
R:R:R34	R:R:W441	4	12	No	Yes	6	8	2	1
R:R:V37	R:R:W441	9.81	12	Yes	Yes	5	8	1	1
R:R:V37	W:W:?1	4.97	12	Yes	No	5	0	1	0
R:R:T437	R:R:W441	4.85	12	No	Yes	6	8	2	1
R:R:W441	W:W:?1	15.19	12	Yes	No	8	0	1	0
R:R:F41	R:R:V37	2.62	0	No	Yes	7	5	2	1
R:R:L38	R:R:W441	2.28	0	No	Yes	7	8	2	1
R:R:I33	R:R:V37	1.54	0	No	Yes	4	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
50.00	Single	8W8S	AA-14	8W8S-GPR101-AA-14
28.57	Single	7F61	Cholesterol	7F61-H₃-PF-03654746-Cholesterol
28.57	Consensus	h3_on_allo	Other Ligand	7F61-H₃-PF-03654746-Cholesterol
16.67	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
16.67	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
16.67	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
16.67	Consensus	ep_off	Orthosteric Ligand	ep4_off
11.11	Single	7XP6	Strychnine	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
11.11	Consensus	class-t_on	Orthosteric Ligand	taste2_on
11.11	Consensus	gs_class-t	Orthosteric Ligand	gs_taste
11.11	Consensus	gs_taste	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
11.11	Consensus	taste2_on	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
10.00	Single	5U09	Taranabant	5U09-CB₁-Taranabant
9.09	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
9.09	Single	8JD6	N-(3-chlorophenyl)pyridine-2-carboxamide	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
9.09	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
9.09	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/&β;1/&γ;2
9.09	Consensus	cb1_off	Orthosteric Ligand	5TGZ-CB₁-AM6538 5U09-CB₁-Taranabant
8.33	Single	2Y01	Dobutamine	2Y01-β₁-Dobutamine
8.33	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
8.33	Single	6IIV	Daltroban	6IIV-TP-Daltroban
8.33	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off leuko_off lpl_off paf_off prostanoid_off
8.33	Consensus	prostanoid_off	Orthosteric Ligand	ep_off tp_off dp_off
8.33	Consensus	tp_off	Orthosteric Ligand	6IIV-TP-Daltroban 6IIU-TP-Ramatroban
7.69	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
7.69	Single	4JKV	Taladegib (LY2940680)	4JKV-SMO-Taladegib (LY2940680)
7.69	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
7.69	Single	6GPX	MK0812	6GPX-CCR2-MK0812
7.69	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
7.69	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/&β;1/&γ;2
7.69	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
7.69	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2
7.69	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/&β;1/&γ;2
7.69	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
7.69	Consensus	ccr2_off_allo	Other Ligand	5T1A-CCR2-PubChem 68764898; PubChem 12093170 6GPX-CCR2-MK0812
7.69	Consensus	ep3_on	Orthosteric Ligand	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
7.14	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
7.14	Single	5V56	TC114	5V56-SMO-TC114
7.14	Single	5V57	TC114	5V57-SMO-TC114
7.14	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
7.14	Single	7R0C	Acyclovir triphosphate	7R0C-V₂-Acyclovir triphosphate-Arrestin2
7.14	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
7.14	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7.14	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
7.14	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/&β;1/&γ;2
7.14	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
6.67	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
6.67	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
6.67	Single	6H7N	(S)-Xamoterol	6H7N-β₁-(S)-Xamoterol
6.67	Single	6IIU	Ramatroban	6IIU-TP-Ramatroban
6.67	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1
6.67	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2
6.67	Consensus	beta1_on	Orthosteric Ligand	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
6.67	Consensus	cannabinoid_off	Orthosteric Ligand	cb1_off cb2_off
6.67	Consensus	ep_on	Orthosteric Ligand	ep4_on ep2_on ep3_on
6.67	Consensus	gi_prostanoid	Orthosteric Ligand	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2 8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
6.67	Consensus	prostanoid_on	Orthosteric Ligand	ep_on fpa_on
6.25	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
6.25	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/&β;1/&γ;2
6.25	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2
6.25	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
6.25	Single	8XJO	U46619	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.25	Consensus	ep2_on	Orthosteric Ligand	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
6.25	Consensus	ep4_on	Orthosteric Ligand	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2
6.25	Consensus	fpa_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.25	Consensus	gs_lipid	Orthosteric Ligand	gs_ffa gs_prostanoid
6.25	Consensus	gs_prostanoid	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2 7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.25	Consensus	ot_on	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
5.88	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.88	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.88	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.88	Consensus	go_vasopressin	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
5.56	Single	4AMJ	(S)-Carvedilol	4AMJ-β₁-(S)-Carvedilol
5.56	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
5.56	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
5.56	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
5.26	Consensus	vasopressin-ot_on	Orthosteric Ligand	ot_on v2_on
4.76	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
4.76	Consensus	bk2_on	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
4.76	Consensus	class-d_on	Orthosteric Ligand	ste2_on
4.76	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
4.76	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
4.76	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
4.55	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2
4.55	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
4.55	Single	7KH0	Acyclovir triphosphate	7KH0-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
4.55	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
4.55	Consensus	bk1_on	Orthosteric Ligand	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.55	Consensus	gs_bradykinin	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.35	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
4.35	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on bk1_on
4.35	Consensus	class-d_on	Orthosteric Ligand	ste2_on
4.35	Consensus	gs_vasopressin-ot	Orthosteric Ligand	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
4.17	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
4.17	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.17	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
4.17	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
4.00	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:F96	W:W:?2	24.36	No	No	4	0	1	0
R:R:N100	W:W:?2	13.73	No	No	8	0	1	0
R:R:F103	W:W:?2	10.15	No	No	5	0	1	0
R:R:F96	R:R:L95	2.44	No	No	4	5	1	2
R:R:F103	R:R:L99	2.44	No	No	5	7	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
66.67	Single	8W8S	AA-14	8W8S-GPR101-AA-14
16.67	Single	8TLM	Anti-murine CCR8 antibody	8TLM-CCR8-Anti-murine CCR8 antibody
16.67	Consensus	ccr8_off	Orthosteric Ligand	8TLM-CCR8-Anti-murine CCR8 antibody
9.09	Single	4XNV	BPTU	4XNV-P2Y₁-BPTU
7.69	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
6.90	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
6.67	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
6.67	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
6.25	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
6.25	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.25	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
6.25	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/&β;1/&γ;2
6.25	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
5.88	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
5.88	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
5.88	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
5.88	Consensus	gs_galanin	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
5.26	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
5.26	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin 8HN1-Alpha1A-Toxin AdTx1
5.00	Single	8IOC	Gamma-MSH	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
5.00	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off alpha1b_off
4.76	Single	7F4D	Alpha-MSH	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2
4.76	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
4.76	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
4.55	Single	7DW9	Acyclovir triphosphate	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
4.55	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
4.35	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
4.35	Consensus	gs_melanocortin	Orthosteric Ligand	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2 7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2
4.35	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
4.17	Consensus	gi_neuromedin	Orthosteric Ligand	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
4.00	Single	7F53	Alpha-MSH	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2
4.00	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
3.57	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
3.57	Consensus	melanocortin_on	Orthosteric Ligand	mc2_on mc1_on mc3_on mc4_on mc5_on
3.45	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
2.78	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1

PDB Summary
PDB	8W8R
Class	A
SubFamily	Orphan
Type	A orphans
SubType	GPR101
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	AA-14
Protein Partners	chim(NtGi1-Gs)/Beta1/Gamma2
PDB Resolution	3.3
Date	2024-01-03
D.O.I.	10.1038/s41589-023-01456-6

Net Summary
I_min	2.69
Number of Linked Nodes	846
Number of Links	971
Number of Hubs	132
Number of Links mediated by Hubs	493
Number of Communities	39
Number of Nodes involved in Communities	199
Number of Links involved in Communities	258

Path Summary
Number Of Nodes in MetaPath	152
Number Of Links MetaPath	151
Number of Shortest Paths	781704
Length Of Smallest Path	3
Average Path Length	28.6446
Length of Longest Path	59
Minimum Path Strength	1.285
Average Path Strength	5.6454
Maximum Path Strength	19.045
Minimum Path Correlation	0.7
Average Path Correlation	0.976598
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.94118
Average % Of Corr. Nodes	45.8413
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	42.6469
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	U7D
PDB Residues	W:W:?1 W:W:?2
Environment Details	Open EMBL-EBI Page
Code	U7D
Name	1-(4-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]thiourea
Synonyms	CHEMBL2134995
Identifier	1-(4-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]thiourea
Formula	C14 H12 F3 N3 S
Molecular Weight	311.325
SMILES	Cc1ccnc(c1)NC(=S)Nc2cccc(c2)C(F)(F)F
PubChem	848971
Formal Charge	0
Total Atoms	33
Total Chiral Atoms	0
Total Bonds	34
Total Aromatic Bonds	12


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63092
Sequence	>8W8R_Chain_A T L S A E D K A A V E R S K M I E K Q L Q K D K Q V Y R A T H R L L L L G A D N S G K S T I V K Q M R I Y V K T S G I F E T K F Q V D K V N F H M F D V G A Q R D E R R K W I Q C F N D V T A I I F V V D S S D Y N R L Q E A L N D F K S I W N N R W L R T I S V I L F L N K Q D L L A E K V L A G K S K I E D Y F P E F A R Y T T P E D A T P E P G E D P R V T R A K Y F I R D E F L R I S T A S G D G R H Y C Y P H F T C S V D T E N A R R I F N D C R D I I Q R M H L R Q Y E L L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>8W8R_Chain_B Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q96P66
Sequence	>8W8R_Chain_R L A H G I I R S T V L V I F L A A S F V G N I V L A L V L Q R K P Q L L Q V T N R F I F N L L V T D L L Q I S L V A P W V V A T S V P L F W P L N S H F C T A L V S L T H L F A F A S V N T I V V V S V D R Y L S I I H P L S Y P S K M T Q R R G Y L L L Y G T W I V A I L Q S T P P L Y G W G Q A A F D E R N A L C S M I W G A S P S Y T I L S V V S F I V I P L I V M I A C Y S V V F C A A R R Q H A L L Y N C K A A K V I F I I I F S Y V L S L G P Y C F L A V L A V W V D V E T Q V P Q W V I T I I I W L F F L Q C C I H P Y V Y G Y M H K T I K K E I Q D M L K K F F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>8W8R_Chain_G N T A S I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8W8Q	A	Orphan	A orphans	GPR101	Homo sapiens	-	-	Gs/&β;1/&γ;2	2.89	2024-01-03	10.1038/s41589-023-01456-6
	8W8R	A	Orphan	A orphans	GPR101	Homo sapiens	-	AA-14	chim(NtGi1-Gs)/&β;1/&γ;2	3.3	2024-01-03	10.1038/s41589-023-01456-6
	8W8S	A	Orphan	A orphans	GPR101	Homo sapiens	-	AA-14	-	3.3	2024-01-03	10.1038/s41589-023-01456-6

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